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CN112595821A - Biological capsule solubility detection device that can contrast - Google Patents

Biological capsule solubility detection device that can contrast Download PDF

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Publication number
CN112595821A
CN112595821A CN202011330042.3A CN202011330042A CN112595821A CN 112595821 A CN112595821 A CN 112595821A CN 202011330042 A CN202011330042 A CN 202011330042A CN 112595821 A CN112595821 A CN 112595821A
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China
Prior art keywords
assembly
solubility
frame
rod
guide rail
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Granted
Application number
CN202011330042.3A
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Chinese (zh)
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CN112595821B (en
Inventor
高贱英
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Hubei Guangren Medicament Co ltd
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Individual
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention relates to a detection device, in particular to a biological capsule solubility detection device capable of carrying out comparison. The technical problems to be solved by the invention are as follows: the biological capsule solubility detection device is simple in operation and capable of visually detecting the solubility of a biological capsule and performing comparison. A comparative biological capsule solubility testing device, comprising: a support frame; the water storage frames are arranged on two sides of the support frame; the fixing frame is arranged on the supporting frame; the driving assembly is arranged on the supporting frame; the stirring assembly is arranged between the water storage frame and the driving assembly; and the placing assembly is arranged on the fixed frame. According to the invention, the solubility contrast detection of the biological capsules is carried out in the water storage frame, and the water in the water storage frame is stirred by the driving component and the stirring component, so that the dissolution of substances in the biological capsules is accelerated, and the solubility contrast detection of the biological capsules is accelerated.

Description

Biological capsule solubility detection device that can contrast
Technical Field
The invention relates to a detection device, in particular to a biological capsule solubility detection device capable of carrying out comparison.
Background
Biocapsules are biocapsulations of cells, enzymes, drugs, magnetic materials, isotopes, absorbents, hemoglobin, and other materials.
When detecting the difference between the same kind of biological capsule, also can carry out the solubility to biological capsule and detect, the staff can open biological capsule, make the material of capsule the inside fall into the water storage frame that is equipped with water, thereby look over biological capsule's solubility, open another biological capsule of the same kind afterwards, make the material of capsule the inside fall into another water storage frame that is equipped with water, observe biological capsule's solubility once more and compare, can't comparatively audio-visual biological capsule's solubility detects like this, it is comparatively troublesome during the detection.
Therefore, it is necessary to design a comparative biocapsule solubility detecting apparatus which is simple in operation and can intuitively detect the solubility of the biocapsule.
Disclosure of Invention
In order to overcome the present solubility of carrying out biological capsule when detecting, can't comparatively audio-visual solubility of carrying out biological capsule detects, comparatively troublesome shortcoming during the detection, the technical problem that solves: the biological capsule solubility detection device is simple in operation and capable of visually detecting the solubility of a biological capsule and performing comparison.
The technical scheme is as follows: a comparative biological capsule solubility testing device, comprising: a support frame; the water storage frames are arranged on two sides of the support frame; the fixing frame is arranged on the supporting frame; the driving assembly is arranged on the supporting frame; the stirring assembly is arranged between the water storage frame and the driving assembly; and the placing assembly is arranged on the fixed frame.
Further, the driving assembly comprises: an electric motor mounted on the support frame; the rotating rods are rotatably arranged on two sides of the supporting frame; a spiral cylinder installed on the rotating rod; a rotating shaft installed on the electric motor; the belt pulley assembly is arranged between the rotating shaft and the rotating rod.
Further, the stirring subassembly includes: the gear ring is rotatably arranged on the water storage frame; the gear is arranged on the rotating rod, and the gear on the same side is meshed with the gear ring; the stirring pieces are arranged on the gear ring at intervals.
Further, the placing component comprises: the sliding rails are symmetrically arranged on two sides of the fixed frame; the sliding block is arranged on the sliding rail in a sliding manner; and the placing plate is arranged on the sliding block.
Further, still including compressing tightly the subassembly, compressing tightly the subassembly including: the supporting plate is arranged between the slide rails on the same side; the first guide rail is arranged on the support plate; the second guide rail is slidably arranged on the first guide rail; the connecting rods are arranged on two sides of the second guide rail in a sliding manner; the first spring is arranged between the connecting rod and the second guide rail; the fixed rod is arranged on the second guide rail and is in sliding fit with the first guide rail; the third guide rail is arranged on the placing plate, and the connecting rod is in sliding fit with the third guide rail; the pressing plate is arranged on the connecting rod; the first special-shaped rod is installed on the fixing rod and matched with the spiral cylinder on the same side.
Further, still include the pushing assembly, the pushing assembly includes: the connecting rods are arranged on two sides of the first guide rail; the wedge block is arranged on the connecting rod and matched with the connecting rod.
Further, still including going out liquid subassembly, it includes to go out liquid subassembly: the fixing plate is arranged on the supporting frame; the liquid outlet pipe is arranged between the water storage frames and is connected with the fixing plate; and the valve is arranged on the liquid outlet pipe.
Further, still including the vibration subassembly, the vibration subassembly includes: the cam is arranged on the rotating rod; the second special-shaped rod is arranged on the supporting plate in a sliding mode and matched with the cam on the same side; the second spring is arranged between the two sides of the second special-shaped rod and the supporting plate; the backing plate is installed on the second special-shaped rod, and the backing plate is matched with the placing plate.
The invention has the beneficial effects that: 1. according to the invention, the solubility contrast detection of the biological capsules is carried out in the water storage frame, and the water in the water storage frame is stirred by the driving component and the stirring component, so that the dissolution of substances in the biological capsules is accelerated, and the solubility contrast detection of the biological capsules is accelerated;
2. the driving assembly can also drive the compressing assembly to move and automatically open the biological capsule under the coordination of the pushing assembly, and simultaneously, the driving assembly can also drive the vibrating assembly to move so that substances in the biological capsule can quickly enter the water storage frame;
3. according to the invention, after the biological capsule solubility detection is finished, water in the water storage frame can be taken out for treatment through the liquid outlet assembly.
Drawings
Fig. 1 is a schematic perspective view of the present invention.
Fig. 2 is a schematic perspective view of the driving assembly of the present invention.
Fig. 3 is a schematic perspective view of the stirring assembly of the present invention.
Fig. 4 is a schematic perspective view of the placement module of the present invention.
Fig. 5 is a schematic perspective view of the compressing assembly of the present invention.
Fig. 6 is a schematic perspective view of the pushing assembly of the present invention.
Fig. 7 is a schematic perspective view of a liquid outlet assembly according to the present invention.
Fig. 8 is a schematic perspective view of the vibration assembly of the present invention.
Part names and serial numbers in the figure: 1: support frame, 2: water storage frame, 3: mount, 4: drive assembly, 41: electric motor, 42: turning rod, 43: helical cylinder, 44: rotating shaft, 45: pulley assembly, 5: stirring assembly, 51: ring gear, 52: gear, 53: stirring blade, 6: placement assembly, 61: slide rail, 62: slider, 63: placing plate, 7: pressing assembly, 71: support plate, 72: first guide rail, 73: second guide rail, 74: connecting rod, 75: first spring, 76: fixing rod, 77: third guide rail, 78: platen, 79: first profile bar, 8: pushing assembly, 81: connecting rod, 82: wedge block, 9: a liquid outlet assembly, 91: fixing plate, 92: drain pipe, 93: valve, 10: vibration assembly, 101: cam, 102: second profile bar, 103: second spring, 104: a backing plate.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The utility model provides a biological capsule solubility detection device that can contrast, as shown in fig. 1 to 4, including support frame 1, water storage frame 2, mount 3, drive assembly 4, stirring subassembly 5 and place subassembly 6, the support frame 1 upper portion left and right sides all has water storage frame 2 through the bolt rigid coupling, 1 upper portion of support frame is connected with mount 3, be equipped with drive assembly 4 on the support frame 1, be equipped with stirring subassembly 5 between water storage frame 2 and the drive assembly 4, be equipped with on the mount 3 and place subassembly 6.
When the solubility detection work of biological capsule is carried out to needs, add equivalent clear water in earlier to two water storage frame 2, place two biological capsules of the same race on placing subassembly 6 afterwards, and open biological capsule with placing subassembly 6 cooperation, make the material in the biological capsule fall into water storage frame 2, then alright control drive assembly 4 begins work, drive stirring subassembly 5 and move, stir in the water storage frame 2, alright contrast the detection to biological capsule's solubility this moment, detect the completion after, alright control drive assembly 4 stop work, and take out the water in the water storage frame 2 and handle.
Drive assembly 4 is including electric motor 41, bull stick 42, spiral drum 43, pivot 44 and belt pulley assembly 45, and 1 upper portion rear side of support frame has electric motor 41 through the bolt rigid coupling, and the equal rotary type in the 1 left and right sides of support frame is equipped with bull stick 42, and bull stick 42 middle part all is equipped with spiral drum 43, and electric motor 41 upper portion is connected with pivot 44, all is equipped with belt pulley assembly 45 between pivot 44 and the bull stick 42.
After the material in the biological capsule falls into water storage frame 2, alright control electric motor 41 begins work, and electric motor 41 can drive pivot 44 and rotate to drive bull stick 42 through pulley subassembly 45 and rotate, just can drive stirring subassembly 5 when bull stick 42 is rotatory and move, after the solubility of biological capsule detects the completion, alright control electric motor 41 stop work.
The stirring assembly 5 comprises a gear ring 51, a gear 52 and stirring blades 53, the gear ring 51 is rotatably arranged on the upper portion of the water storage frame 2, the gear 52 is connected to the upper portion of the rotating rod 42 in a key mode, the gear 52 and the gear ring 51 on the same side are meshed with each other, and six stirring blades 53 are uniformly arranged on the gear ring 51 at intervals.
When the bull stick 42 rotated, still can drive gear 52 rotatory, gear 52 is rotatory just can drive ring gear 51 and stirring piece 53 rotatory, just can stir water storage frame 2 inside when stirring piece 53 is rotatory, dissolves with higher speed the material in the biological capsule, and after the solubility of biological capsule detected the completion, the bull stick 42 stopped rotatory, and stirring subassembly 5 stop motion.
Place subassembly 6 including slide rail 61, slider 62 and place board 63, the equal bilateral symmetry in the left and right sides of mount 3 is equipped with slide rail 61, and slide rail 61 upper portion all is slidingtype to be equipped with slider 62, and slider 62 upper portion all is connected with places board 63.
When the solubility of biological capsule detects the work as the needs, place biological capsule on two close boards 63, fix biological capsule on placing board 63 afterwards manually to control and place board 63 and keep away from each other, thereby open biological capsule, make the material in biological capsule fall into water storage frame 2, afterwards take out the shell of biological capsule to handle can.
Example 2
On the basis of embodiment 1, as shown in fig. 1, 5, 6, 7 and 8, the pressing device 7 further includes a pressing assembly 7, the pressing assembly 7 includes a supporting plate 71, a first guide rail 72, a second guide rail 73, a connecting rod 74, a first spring 75, a fixing rod 76, a third guide rail 77, a pressing plate 78 and a first special-shaped rod 79, the supporting plate 71 is fixedly connected between the slide rails 61 on the same side through bolts, the first guide rail 72 is fixedly connected to the rear side of the upper portion of the supporting plate 71 through bolts, the second guide rail 73 is slidably arranged on the first guide rail 72, the connecting rod 74 is slidably arranged on both left and right sides of the second guide rail 73, the first spring 75 is connected between the connecting rod 74 and the second guide rail 73, the fixing rod 76 is connected to the middle portion of the second guide rail 73, the fixing rod 76 is slidably engaged with the first guide rail 72, the third guide rail 77 is fixedly connected to the outer side of the placing plate 63 through bolts, the inner sides of the connecting rods 74 are connected with pressing plates 78, the fixing rods 76 are connected with first special-shaped rods 79, and the first special-shaped rods 79 are matched with the spiral cylinders 43 on the same side.
When the rotating rod 42 rotates, the spiral cylinder 43 is driven to rotate, so that the first special-shaped rod 79, the fixed rod 76, the second guide rail 73, the connecting rod 74, the first spring 75 and the pressing plate 78 move downwards, the pressing plate 78 moves downwards to press the biological capsule, then the connecting rod 74 can be controlled to move towards the outer side of the second guide rail 73, at the moment, the first spring 75 is stretched, when the connecting rod 74 moves, the third guide rail 77, the pressing plate 78, the placing plate 63 and the sliding block 62 are also driven to move, so that the biological capsule is opened, when the substance in the biological capsule falls into the water storage frame 2, the connecting rod 74 is released, at the moment, the first spring 75 automatically resets, and drives the connecting rod 74, the third guide rail 77, the pressing plate 78, the placing plate 63 and the sliding block 62 to move, then the spiral cylinder 43 can be driven by the electric motor 41 to rotate reversely, so that the whole pressing, the shells of the biocapsules on the resting plate 63 can then be taken out for processing, thus eliminating the need for the user to manually open the biocapsules.
Still including pushing assembly 8, pushing assembly 8 is including connecting rod 81 and wedge 82, and the first guide rail 72 middle part left and right sides all is connected with connecting rod 81, and the connecting rod 81 outer end all is connected with wedge 82, and wedge 82 cooperates with connecting rod 74.
When the connecting rod 74 moves downwards to a certain degree, the connecting rod 74 can be in contact with the wedge block 82, under the action of the wedge block 82, the connecting rod 74 moves towards the outer side of the second guide rail 73, after the connecting rod 74 moves upwards, the connecting rod is not in contact with the wedge block 82 any more, and the connecting rod is automatically reset under the action of the first spring 75, so that a user does not need to manually pull the connecting rod 74 to move.
Still including going out liquid subassembly 9, go out liquid subassembly 9 including fixed plate 91, drain pipe 92 and valve 93, the middle part of 1 front side of support frame is connected with fixed plate 91, is connected with drain pipe 92 between 2 lower parts of water storage frame, and drain pipe 92 is connected with fixed plate 91, is connected with valve 93 on the drain pipe 92.
After the biological capsule solubility detection is completed, the valve 93 can be opened, so that the water in the water storage frame 2 flows out through the liquid outlet pipe 92 for treatment, and after the water in the water storage frame 2 completely flows out, the valve 93 is closed.
Still including vibration subassembly 10, vibration subassembly 10 is including cam 101, second deformed bar 102, second spring 103 and backing plate 104, bull stick 42 upper portion all is connected with cam 101, all slidingtype is equipped with second deformed bar 102 on the backup pad 71, second deformed bar 102 and the cooperation of the cam 101 of homonymy, be connected with second spring 103 between the second deformed bar 102 left and right sides and the backup pad 71, second deformed bar 102 front side is connected with backing plate 104, backing plate 104 and the cooperation of placing board 63.
When the rotating rod 42 rotates, the cam 101 is driven to rotate, after the cam 101 rotates to be in contact with the second special-shaped rod 102, the second special-shaped rod 102 and the backing plate 104 are driven to move towards the rear side, the second spring 103 is compressed at the moment, and after the cam 101 rotates to be not in contact with the second special-shaped rod 102, the second spring 103 resets to drive the second special-shaped rod 102 and the backing plate 104 to reset, so that the backing plate 104 is in contact with the placing plate 63, the placing plate 63 shakes, and the substances in the biological capsule fall into the water storage frame 2.
While the present invention has been described with reference to exemplary embodiments, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. The scope of the following claims is to be accorded the broadest interpretation so as to encompass all such modifications and equivalent structures and functions.

Claims (8)

1. A comparable biological capsule solubility testing apparatus, comprising:
a support frame (1);
the water storage frames (2) are arranged on two sides of the support frame (1);
the fixing frame (3) is arranged on the supporting frame (1);
the driving assembly (4) is arranged on the support frame (1);
the stirring component (5) is arranged between the water storage frame (2) and the driving component (4);
the placing component (6) is arranged on the fixing frame (3).
2. A comparative biocapsule solubility detection apparatus as claimed in claim 1 wherein the drive assembly (4) comprises:
an electric motor (41) mounted on the support frame (1);
the rotating rods (42) are rotatably arranged on two sides of the support frame (1);
a spiral cylinder (43) mounted on the rotating rod (42);
a rotating shaft (44) mounted on the electric motor (41);
and the pulley assembly (45) is arranged between the rotating shaft (44) and the rotating rod (42).
3. A comparative biocapsule solubility test apparatus according to claim 2 wherein the agitation assembly (5) comprises:
the gear ring (51) is rotatably arranged on the water storage frame (2);
the gear (52) is arranged on the rotating rod (42), and the gear (52) on the same side is meshed with the gear ring (51);
and at least two stirring blades (53) are arranged on the gear ring (51) at uniform intervals.
4. A comparative biocapsule solubility testing apparatus as claimed in claim 3 wherein the positioning assembly (6) comprises:
the sliding rails (61) are symmetrically arranged on two sides of the fixed frame (3);
a slide block (62) which is slidably mounted on the slide rail (61);
a placing plate (63) mounted on the slider (62).
5. A comparative biocapsule solubility detection apparatus according to claim 4, further comprising a compacting assembly (7), the compacting assembly (7) comprising:
a support plate (71) mounted between the slide rails (61) on the same side;
a first rail (72) mounted on the support plate (71);
a second rail (73) slidably mounted on the first rail (72);
the connecting rods (74) are arranged on two sides of the second guide rail (73) in a sliding manner;
a first spring (75) installed between the connection rod (74) and the second guide rail (73);
the fixing rod (76) is arranged on the second guide rail (73), and the fixing rod (76) is in sliding fit with the first guide rail (72);
the third guide rail (77) is arranged on the placing plate (63), and the connecting rod (74) is in sliding fit with the third guide rail (77);
a pressure plate (78) mounted on the connecting rod (74);
and a first profile bar (79) mounted on the fixing bar (76), the first profile bar (79) being fitted with the spiral cylinder (43) on the same side.
6. A comparative biocapsule solubility detection apparatus according to claim 5, further comprising a pushing assembly (8), the pushing assembly (8) comprising:
connecting rods (81) mounted on both sides of the first guide rail (72);
the wedge block (82) is installed on the connecting rod (81), and the wedge block (82) is matched with the connecting rod (74).
7. A comparative biocapsule solubility detection apparatus according to claim 6, further comprising a tapping assembly (9), the tapping assembly (9) comprising:
a fixing plate (91) mounted on the support frame (1);
the liquid outlet pipe (92) is arranged between the water storage frames (2), and the liquid outlet pipe (92) is connected with the fixing plate (91);
and the valve (93) is arranged on the liquid outlet pipe (92).
8. The apparatus for detecting the solubility of a biocompatible capsule according to claim 7, further comprising a vibration assembly (10), wherein the vibration assembly (10) comprises:
a cam (101) mounted on the rotating rod (42);
the second special-shaped rod (102) is slidably mounted on the support plate (71), and the second special-shaped rod (102) is matched with the cam (101) on the same side;
a second spring (103) installed between both sides of the second profile rod (102) and the support plate (71);
and the backing plate (104) is installed on the second special-shaped rod (102), and the backing plate (104) is matched with the placing plate (63).
CN202011330042.3A 2020-11-24 2020-11-24 Biological capsule solubility detection device capable of conducting comparison Active CN112595821B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011330042.3A CN112595821B (en) 2020-11-24 2020-11-24 Biological capsule solubility detection device capable of conducting comparison

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Application Number Priority Date Filing Date Title
CN202011330042.3A CN112595821B (en) 2020-11-24 2020-11-24 Biological capsule solubility detection device capable of conducting comparison

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CN112595821A true CN112595821A (en) 2021-04-02
CN112595821B CN112595821B (en) 2023-11-10

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114451448A (en) * 2021-12-27 2022-05-10 广东亚北农副产品有限公司 Fruit vegetables freeze-drying is with processing dewatering equipment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN206114351U (en) * 2016-11-04 2017-04-19 胡海涛 Capsule medicine taking device for medicine test
CN209606277U (en) * 2019-01-28 2019-11-08 广东强基药业有限公司 A kind of gelatin hollow capsule processing dissolution detection device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN206114351U (en) * 2016-11-04 2017-04-19 胡海涛 Capsule medicine taking device for medicine test
CN209606277U (en) * 2019-01-28 2019-11-08 广东强基药业有限公司 A kind of gelatin hollow capsule processing dissolution detection device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114451448A (en) * 2021-12-27 2022-05-10 广东亚北农副产品有限公司 Fruit vegetables freeze-drying is with processing dewatering equipment
CN114451448B (en) * 2021-12-27 2024-02-09 广东亚北农副产品有限公司 Processing dewatering equipment for freeze-drying fruits and vegetables

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Effective date of registration: 20231016

Address after: 441300 No. 009 Shichang Road, Industrial Park, Guangshui City, Suizhou City, Hubei Province

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Applicant before: Gao Jianying

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