CN112051406A

CN112051406A - Chemiluminescent immunoassay device

Info

Publication number: CN112051406A
Application number: CN202010696802.6A
Authority: CN
Inventors: 马杰; 陈有顺; 陆卓; 李雪; 陈林林; 谭福登
Original assignee: Shenzhen Rayto Life And Analytical Sciences Co ltd
Current assignee: Shenzhen Rayto Life And Analytical Sciences Co ltd
Priority date: 2020-07-20
Filing date: 2020-07-20
Publication date: 2020-12-08
Anticipated expiration: 2040-07-20
Also published as: CN112051406B

Abstract

The application belongs to the technical field of chemiluminescence immunoassay, and provides chemiluminescence immunoassay equipment which comprises a first rack, a sampling system, an incubation system and a cleaning system, wherein the sampling system, the incubation system and the cleaning system are arranged on the first rack; the incubation system comprises a blending gripper assembly, a sample disc and an incubation disc, wherein the sample disc is provided with a plurality of sample adding positions, the incubation disc is internally provided with a plurality of incubation positions, and the blending gripper assembly is used for blending reaction cups at the sample adding positions and transferring the reaction cups to the incubation positions; the cleaning system comprises a cleaning gripper assembly, a substrate assembly, a first cleaning assembly and a second cleaning assembly, wherein the first cleaning assembly and the second cleaning assembly can clean and separate reaction cups, the first cleaning assembly and the second cleaning assembly respectively comprise a plurality of cleaning positions, and the cleaning gripper assembly is used for transferring the reaction cups to the cleaning positions and transferring the reaction cups, which are cleaned and separated from the first cleaning assembly, to the sample adding positions. Through the application, the test of a plurality of test samples can be completed only by starting once, and the test speed can not be reduced.

Description

Chemiluminescent immunoassay device

Technical Field

The application belongs to the technical field of chemiluminescence immunoassay, and particularly relates to chemiluminescence immunoassay equipment.

Background

Chemiluminescence immunoassay has the advantages of high sensitivity, strong specificity, wide linear range, high automation degree and the like, and becomes a main means of clinical diagnosis. Most of the chemiluminescence immunoassay devices in the current market have low testing speed, and particularly, the testing speed of the whole machine is reduced when a sample reagent needs to be cleaned in two steps.

Disclosure of Invention

An object of the embodiment of the application is to provide a material platform to solve the technical problem that the test speed of chemiluminescence analytical equipment is low in the prior art.

In order to achieve the purpose, the technical scheme adopted by the application on one hand is as follows: the chemiluminescence immunoassay device comprises a first frame, a sampling system, an incubation system and a cleaning system, wherein the sampling system, the incubation system and the cleaning system are arranged on the first frame;

the incubation system comprises a blending gripper assembly, a sample disc and an incubation disc, wherein a plurality of sample adding positions for placing reaction cups are arranged on the sample disc, the sampling system is used for injecting samples and/or reagents into the reaction cups positioned on the sample adding positions, a plurality of incubation positions are arranged in the incubation disc, and the blending gripper assembly is used for transferring the reaction cups injected with the samples and/or the reagents on the sample adding positions to the incubation positions for incubation after blending operation;

the cleaning system comprises a cleaning gripper assembly, a substrate assembly, a first cleaning assembly and a second cleaning assembly, wherein the first cleaning assembly and the second cleaning assembly are arranged on the first rack and can clean and separate reaction cups, the first cleaning assembly and the second cleaning assembly respectively comprise a plurality of cleaning positions, the cleaning gripper assembly is used for transferring the reaction cups positioned at the incubation positions to the cleaning positions and transferring the reaction cups cleaned and separated on the first cleaning assembly to the sample adding position, and the substrate assembly is used for filling substrates into the reaction cups cleaned and separated on the second cleaning assembly.

Optionally, the incubation system further includes a first base and a first cover plate, the first base and the first cover plate enclose to form a first installation chamber, and the sample tray and the incubation tray are coaxially and independently rotatably disposed in the first installation chamber; set up on the first apron and shift hole and charge-in hole, shift to correspond and expose at least one the application of sample position and at least one incubate the position, the charge-in hole corresponds and exposes at least one the application of sample position, sampling system passes through the charge-in hole is to pouring into sample and/or reagent in the reaction cup, mixing tongs subassembly is close to shift the hole set up in on the first apron and still be used for with shift the hole and expose reaction cup on the application of sample position shift after carrying out the mixing operation to shift the hole and expose the position of incubating.

Optionally, cleaning system still includes the washing dish, wash the tongs subassembly with the substrate subassembly set up in wash the dish upside, first wash the subassembly with the second wash the subassembly all including set up in having in the washing dish and being a plurality of that the annular was arranged wash the position wash the pot, set up in wash the dish upside be used for right it carries out the mixing subassembly of solid-liquid mixing to wash the reaction cup in the position, set up in wash on the dish be used for the magnetic separation subassembly of adsorption separation reaction cup solid-liquid and set up in be used for on the washing dish annotate liquid, imbibition and abluent imbibition liquid subassembly to the reaction cup.

Optionally, the optical detection system is arranged on the first rack and comprises a light measuring disc, a light measuring gripper assembly and a signal acquisition and processing assembly, wherein a cup placing position is arranged in the light measuring disc, the light measuring gripper assembly is used for transferring a reaction cup filled with a substrate to the cup placing position, and the signal acquisition and processing assembly is used for acquiring and processing an optical signal sent by a sample in the reaction cup on the cup placing position.

Optionally, still be provided with the position of losing the cup in the first frame, optics detecting system still including set up in survey the last waste liquid subassembly that inhales of optical disc, survey correspond on the optical disc inhale the waste liquid subassembly and be provided with and inhale the waste liquid hole, it can be relative to be provided with in the optical disc first frame pivoted rotation portion, have in the rotation portion put the cup position, rotation portion drives the reaction cup in proper order and docks in with the photometry position that signal acquisition processing assembly corresponds, with inhale waste liquid hole correspond inhale waste liquid position and during the photometry position, supply respectively signal acquisition processing assembly gathers the optical signal that the interior sample of reaction cup sent, supplies inhale the interior liquid of waste liquid subassembly absorption reaction cup and supply photometry tongs subassembly will imbibition reaction cup move extremely lose the cup position.

Optionally, the sampling system comprises a sampling needle assembly, a reagent disk assembly and a reagent needle assembly, the sampling needle assembly is rotatably arranged on the first frame, a sampling position is arranged on the first frame, the sampling needle assembly is arranged between the sampling position and the incubation system and is used for collecting a sample on the sampling position and injecting the sample into a reaction cup, the reagent disk assembly is arranged close to the incubation system and is provided with a plurality of coaxially arranged annular reagent tube positions for placing reagent tubes, and the reagent needle assembly is arranged between the incubation system and the reagent disk assembly and is used for collecting reagents in the reagent tubes and injecting the reagents into the reaction cup.

Optionally, still including set up in advance a cup subassembly and rotatory tongs subassembly on first frame, advance a cup subassembly set up in hatching one side of keeping away from of system the reagent dish subassembly, rotatory tongs subassembly is located hatching system with advance between the cup subassembly, advance a cup subassembly including the cup position of advancing that loads the reaction cup, rotatory tongs subassembly rotatable set up in on the first frame and be used for with advance the reaction cup on the cup position and move to the application of sample position.

Optionally, the device further comprises a second rack connected with the first rack and a front end rail system arranged on the first rack, wherein a sample rack placing area, a sample rack recycling area and a scheduling component are arranged on the second rack, the sample rack placing area is used for storing a sample rack and is arranged on one side of the reagent disc assembly away from the incubation system, and the sample rack recycling area is used for recycling the sample rack and is arranged between the reagent disc assembly and the sample rack placing area;

front end rail system including advance kind rail set spare, become rail set spare and retrieve rail set spare, advance kind rail set spare be used for with in the sample frame places the district the sample frame transport to the sampling position, become rail set spare and be used for with the sample frame is followed advance kind rail set spare transport to retrieve the rail set spare, retrieve the rail set spare be used for with the sample frame transport to the cup mouth that returns of sample frame recovery district, the dispatch subassembly set up in it will to return the cup mouth be used for following the sample frame is followed transfer to on retrieving the rail set spare the sample frame recovery district.

Optionally, advance a kind track subassembly includes conventional track subassembly and emergency call track subassembly, correspond in the second frame emergency call track subassembly is provided with emergency call insertion component, the first end of conventional track subassembly with the first end of emergency call track subassembly all is provided with the sampling position, the second end of conventional track subassembly corresponds the sample frame is placed the play appearance mouth in district, be used for with in the sample frame is placed the district the sample frame transports to corresponding the sampling position, the second end of emergency call track subassembly corresponds the emergency call insertion component sets up and is used for with on the emergency call insertion component the sample frame transports to corresponding the sampling position, the orbital transfer component selectively removes to the first end of conventional track subassembly the first end of emergency call track subassembly with retrieve the first end of track subassembly.

Optionally, including second frame and a plurality of first frame, it is a plurality of first frame connects gradually, just the second frame is connected in a plurality of one side of frame, it is a plurality of between the first frame front end track subassembly corresponds, it can communicate adjacent two to become the rail subassembly on the first frame advance the sample track subassembly and connect adjacent two on the first frame retrieve the track subassembly.

The beneficial effect of this application lies in:

compared with the prior art, the chemiluminescence immunoassay device has the advantages that the chemiluminescence immunoassay device can be started up once to complete the test of a plurality of test samples through the plurality of sample adding positions and incubation positions, the samples do not need to be added in a stopping way, and the test speed of the whole device is improved; simultaneously this application embodiment including first washing subassembly and second washing subassembly, wash tongs subassembly can with the reaction cup after the fourth rank washing separation on the first washing subassembly is transferred to the application of sample position, wash the separation to the reaction cup through at least two sets of washing subassemblies, when the sample reagent in the reaction cup needs to carry out two-step washing, can get back to the application of sample position again after the washing separation and carry out reagent addition on next step, and can not influence the reaction cup on the second washing subassembly and carry out the operation of substrate filling on next step to can not reduce the test speed of complete machine.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise.

FIG. 1 is a schematic diagram of a first structure of a chemiluminescent immunoassay device provided by an embodiment of the present application;

FIG. 2 is a schematic diagram of a second structure of a chemiluminescent immunoassay device provided by an embodiment of the present application;

FIG. 3 is a schematic diagram of a third structure of a chemiluminescent immunoassay device provided by an embodiment of the present application;

FIG. 4 is a top view of a chemiluminescent immunoassay device as provided by the examples herein;

fig. 5 is a schematic structural diagram of an incubation system provided in an embodiment of the present application;

FIG. 6 is a schematic structural diagram of a cleaning system according to an embodiment of the present disclosure;

FIG. 7 is a schematic structural diagram of a blending assembly provided in an embodiment of the present application;

FIG. 8 is a schematic diagram of a liquid intake and injection assembly according to an embodiment of the present disclosure;

FIG. 9 is a schematic structural diagram of an optical inspection system according to an embodiment of the present disclosure;

FIG. 10 is a schematic view of a portion of a cup advancing assembly according to an embodiment of the present disclosure;

FIG. 11 is a schematic view of a portion of a chemiluminescent immunoassay device according to another embodiment of the present application;

FIG. 12 is a front view of a chemiluminescent immunoassay device provided in another embodiment of the present application;

fig. 13 is a test flow chart of the chemiluminescence immunoassay device provided in the embodiment of the present application.

Wherein, in the figures, the respective reference numerals:

the chemiluminescent immunoassay device 10, the first rack 100, the cup losing position 101, the sampling system 120, the sampling needle assembly 121, the reagent disk assembly 122, the reagent needle assembly 123, the sampling position 124, the incubation system 130, the mixing hand assembly 131, the sample disk 132, the incubation disk 133, the sample adding position 134, the incubation position 135, the transfer hole 136, the adding hole 137, the cleaning system 140, the cleaning hand assembly 141, the substrate assembly 142, the cleaning position 143, the cleaning disk 144, the mixing assembly 145, the mixing section 1451, the pipetting assembly 146, the pipetting section 1461, the optical detection system 150, the photometric disk 151, the photometric hand assembly 152, the signal acquisition and processing assembly 153, the pipetting waste liquid assembly 154, the cup feeding assembly 160, the cup feeding position 161, the reaction cup bin 162, the up-and-down transportation assembly 163, the chute 164, the rotating motor 165, the cup feeding disk 166, the rotating hand assembly 167, the sample feeding track assembly 171, the conventional track assembly 1711, the emergency track assembly 1712, the emergency track assembly 171, A track transfer assembly 172, a retrieval track assembly 173, a second rack 200, a sample rack placement section 210, a sample rack retrieval section 220, a scheduling assembly 230, an emergency insertion assembly 240, a sample rack 400, a control system 250, a scanning device 260, a reaction cup 300, a cascade block 500.

Detailed Description

In order to make the technical problems, technical solutions and advantageous effects to be solved by the present application clearer, the present application is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or be indirectly connected to the other element.

It will be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like, as used herein, refer to an orientation or positional relationship indicated in the drawings that is solely for the purpose of facilitating the description and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be considered as limiting the present application.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present application, "a plurality" means two or more unless specifically limited otherwise.

Referring to fig. 1 to 4, a chemiluminescent immunoassay device 10 provided for the application embodiment includes a first rack 100, a sampling system 120 disposed on the first rack 100, an incubation system 130, and a washing system 140;

the incubation system 130 comprises a blending gripper assembly 131, a sample tray 132 and an incubation tray 133, wherein the sample tray 132 is provided with a plurality of sample adding positions 134 for placing the reaction cups 300, the sampling system 120 is used for injecting samples and/or reagents into the reaction cups 300 positioned on the sample adding positions 134, the incubation tray 133 is provided with a plurality of incubation positions 135, and the blending gripper assembly 131 is used for blending the reaction cups 300 injected with the samples and/or the reagents on the sample adding positions 134 and transferring the reaction cups to the incubation positions 135 for incubation;

the cleaning system 140 comprises a cleaning gripper assembly 141, a substrate assembly 142, and a first cleaning assembly and a second cleaning assembly which are arranged on the first rack 100 and can clean and separate the reaction cups 300, wherein the first cleaning assembly and the second cleaning assembly respectively comprise a plurality of cleaning positions 143, the cleaning gripper assembly 141 is used for transferring the reaction cups 300 positioned at the incubation positions 135 to the cleaning positions 143 and transferring the reaction cups 300 cleaned and separated on the first cleaning assembly to the sample adding position 134, and the substrate assembly 142 is used for filling substrates into the reaction cups 300 cleaned and separated on the second cleaning assembly.

When the sample reagent in the reaction cup 300 only needs to be washed in one step (commonly called "one-step method"), the washing handle moves the reaction cup 300 from the incubation position 135 to the washing position 143 of the first washing component, and the substrate is filled at the substrate component 142 after being washed by the first washing component; when the sample reagent in the cuvette 300 needs to undergo two-step washing (commonly referred to as "two-step method"), the washing gripper moves the cuvette 300 from the incubation position 135 to the washing position 143 of the second washing unit, and returns to the loading position 134 after being washed by the second washing unit.

In the embodiment, the device can be started up for testing a plurality of test samples at one time through the plurality of sample adding positions 134 and the incubation positions 135, so that the testing speed of the whole device is improved; the 'one-step' reaction cup 300 and the 'two-step' reaction cup 300 are respectively cleaned by different cleaning components, and the two cleaning components are not interfered with each other, so that the 'two-step' reaction cup 300 cannot influence the subsequent processes of the 'one-step' reaction cup 300, and the testing speed of the whole machine cannot be reduced.

It is understood that the chemiluminescent immunoassay device 10 further comprises a control system 250 in control communication with the incubation system 130 and the washing system 140. The control system 250 controls the incubation system 130 and the washing system 140 to perform the above-mentioned operations.

In one embodiment, referring to fig. 5, the incubation system 130 further includes a first base and a first cover plate enclosing to form a first installation chamber, and the sample tray 132 and the incubation tray 133 are coaxially and independently rotatably disposed in the first installation chamber; the first cover plate is provided with a transfer hole 136 and a feeding hole 137, the transfer hole 136 correspondingly exposes at least one feeding position 134 and at least one incubation position 135, the feeding hole 137 correspondingly exposes at least one feeding position 134, the sampling system 120 injects a sample and/or a reagent into the reaction cup 300 through the feeding hole 137, and the mixing hand grip assembly 131 is arranged on the first cover plate close to the transfer hole 136 and is also used for mixing the reaction cup 300 on the feeding position 134 exposed by the transfer hole 136 and then transferring the reaction cup 300 to the incubation position 135 exposed by the transfer hole 136.

Wherein, the quantity of charge door 137 can be a plurality of, can set for according to actual demand. In one embodiment, the number of feed holes 137 is three, wherein one feed hole 137 is used for adding the sample, one feed hole 137 is used for adding the first reagent, and one feed hole 137 is used for adding the second reagent.

Wherein transfer well 136 is sized to expose at least one loading site 134 and at least one incubation site 135 simultaneously. And when the blending grip assembly 131 is blended, the at least one incubation position 135 exposed in the transfer hole 136 includes the incubation position 135 where the reaction cup 300 is not placed.

Wherein, the mixing hand grip assembly 131 is inserted into the transfer hole 136 to grip the reaction cup 300 on the sample loading position 134 for mixing, and then directly sends the reaction cup 300 to the incubation position 135 in the transfer hole 136.

It will be appreciated that incubation system 130 also includes a first drive mechanism that drives rotation of sample tray 132 and a second drive mechanism that drives rotation of incubation tray 133. The control system 250 is electrically connected to the first driving mechanism and the second driving mechanism, and controls the first driving mechanism and the second driving mechanism to work to drive the sample tray 132 and the incubation tray 133 to rotate by the command angle, respectively. The first driving mechanism and the second driving mechanism may be motors or combinations of motors and various transmission systems, which is not limited herein.

In a specific example, the sample tray 132 is located outside the incubation tray 133, the sample tray 132 includes a circle of sample application sites 134, the incubation tray 133 includes a plurality of circles of incubation sites 135, and it is mainly considered that the reaction cups 300 at the incubation sites 135 need to be incubated for a period of time, that is, the fluidity of the reaction cups 300 at the incubation sites 135 is smaller than that of the reaction cups 300 at the sample application sites 134, and the number of the incubation sites 135 is greater than that of the sample application sites in order not to decrease the testing speed.

The incubation system 130 may also include other structures, such as a temperature control component for controlling the incubation temperature, and is not limited herein.

In this embodiment, the sample tray 132 and the incubation tray 133 are integrated in the first mounting chamber, which is beneficial to reduce the size of the apparatus; simultaneously, will mix the tongs integration on first apron, further utilize equipment working face space, reduce the equipment size, be favorable to realizing the miniaturization of equipment, simultaneously, through sample dish 132 with hatch a set 133 coaxial arrangement, reduce the transport time of mixing tongs subassembly 131 for the test process.

Exemplarily, the blending gripper comprises a displacement driving mechanism, a displacement table connected with the displacement driving mechanism, and a third driving mechanism and a gripper mechanism which are arranged on the displacement table, wherein the third driving mechanism is connected with the gripper mechanism and drives the gripper mechanism to rotate, and the displacement driving mechanism drives the displacement table to move on a horizontal plane and a vertical plane. When the displacement driving mechanism drives the displacement table to move, the gripper mechanism and the third driving mechanism are driven to move to the position above the material adding position or the incubation position 135 exposed by the transfer hole 136, the gripper mechanism is switched between the opening state and the closing state to grip the reaction cup 300, and the third driving mechanism is used for driving the gripper mechanism to rotate the reaction cup 300 so as to complete the blending operation. The gripper mechanism can realize the driving of the switching of the working state through a mechanical transmission structure, for example, the gripper mechanism can comprise a plurality of grippers, one end of each gripper can be used for gripping the reaction cup 300, the other end of each gripper serves as a driving end, the middle part of each gripper can be hinged to a fixed part, the other ends of the plurality of grippers can be connected with the same driving part, the driving part moves along the vertical direction to drive one ends of the plurality of grippers to rotate, and the gripper mechanism can be switched between the opening state and the closing state.

The blending hand grip can also adopt other existing modes, and is not limited here.

In an optional embodiment, referring to fig. 6, the cleaning system 140 further includes a cleaning tray 144, the cleaning gripper assembly 141 and the substrate assembly 142 are disposed on the upper side of the cleaning tray 144, each of the first cleaning assembly and the second cleaning assembly includes a cleaning pan rotatably disposed in the cleaning tray 144 and having a plurality of cleaning positions 143 arranged in a ring shape, a blending assembly 145 disposed on the upper side of the cleaning tray 144 and used for blending solid and liquid in the reaction cups 300 on the cleaning positions 143, a magnetic separation assembly disposed on the cleaning tray 144 and used for adsorbing and separating solid and liquid in the reaction cups 300, and a liquid injection assembly 146 disposed on the cleaning tray 144 and used for injecting, absorbing and cleaning the reaction cups 300, and the cleaning pan of the first cleaning assembly and the cleaning pan of the second cleaning assembly can rotate relatively independently.

Wherein, and the washing pot of first washing subassembly and the washing pot coaxial and independent rotation setting of second washing subassembly.

Illustratively, the cleaning disc 144 includes a second base and a second cover plate, the second base and the second cover plate enclose to form a second mounting cavity, a first cleaning pot and a second cleaning pot which can rotate independently are coaxially disposed in the second mounting cavity, and a plurality of cleaning positions 143 are disposed on the first cleaning pot and the second cleaning pot. Liquid subassembly 146 is annotated to mixing subassembly 145 and imbibition installs on the second apron, and the magnetic separation subassembly is installed in the second installation cavity, washs the pot to correspond first washing pot and second and installs the magnetic separation subassembly respectively, and just corresponds a mixing subassembly 145 and a imbibition notes liquid subassembly 146 configuration and has a magnetic bead separation subassembly.

In one embodiment, referring to fig. 6, 7 and 8, the cleaning system 140 is a fourth-order cleaning system 140, and includes a first blending assembly, a first liquid-absorbing and injecting assembly, a second blending assembly and a second liquid-absorbing and injecting assembly, which are sequentially disposed, the first blending assembly and the second blending assembly include two sets of blending parts 1451, and each set of blending parts 1451 corresponds to a first blending part of the first cleaning assembly and a second blending part corresponding to the second cleaning assembly; first imbibition notes liquid subassembly and second imbibition notes liquid subassembly all include two sets of imbibitions notes liquid portion 1461, and every imbibition notes liquid portion 1461 of group all includes with correspond first imbibition notes liquid portion of wasing the subassembly and with correspond the second imbibition notes liquid portion that the second washs the subassembly and corresponds. The magnetic bead separation assembly includes a magnetic separation portion corresponding to the mixing portion 1451 and the liquid-suction liquid injection portion 1461, and the magnetic separation portion includes a first magnetic separation portion corresponding to the first cleaning assembly and a second magnetic separation portion corresponding to the second cleaning assembly. Wherein, one mixing part 1451, one liquid sucking and injecting part 1461 and one magnetic separation part form a group of cleaning groups and complete a cleaning stage for the reaction cup 300. The process of one cleaning stage comprises liquid injection, uniform mixing, magnetic bead separation and waste liquid absorption; thus, four cleaning sets can achieve four-step cleaning of the cuvette 300.

Each of the blending parts 1451 includes two blending ends, one of which corresponds to the first cleaning pot and the other of which corresponds to the second cleaning pot. Meanwhile, the liquid suction and injection part 1461 also comprises two needle ends, one needle end corresponds to the first cleaning pot, the other needle end corresponds to the second cleaning pot, and a needle tube is arranged at the needle tube end and used for injecting liquid into the reaction cup and absorbing the liquid in the reaction cup.

Further, the blending assembly 145 and the liquid absorbing and injecting assembly 146 are integrated on a mounting rack, and the specific structure can refer to the existing structure, which is not described herein.

In this embodiment, through the cleaning system, through two blending assemblies 145 and two imbibition liquid injection assemblies 146, the four-stage cleaning can be realized, and the cleaning system has the characteristic of compact structure.

In one embodiment, referring to fig. 1 to 4 and fig. 9, the chemiluminescent immunoassay device 10 further comprises an optical detection system 150 disposed on the first housing 100, the optical detection system 150 comprises a photometric disk 151, a photometric grip assembly 152 and a signal acquisition and processing assembly 153, a cup placing position is disposed in the photometric disk 151, the photometric grip assembly 152 is used for transferring the reaction cup 300 filled with the substrate to the cup placing position, and the signal acquisition and processing assembly 153 is used for acquiring and processing optical signals emitted by the sample in the reaction cup 300 on the cup placing position.

Wherein the optical detection system 150 is located at one side of the cleaning system 140.

As can be appreciated, referring to fig. 1-4, the control system 250 includes a host computer in signal communication with the signal acquisition and processing component 153, the host computer receiving and processing data sent by the signal acquisition and processing component 153 and generating test results.

In a practical embodiment, referring to fig. 9, the first rack 100 is further provided with a cup losing position 101, the optical detection system 150 further includes a waste liquid absorbing assembly 154 disposed on the optical disc 151, a waste liquid absorbing hole is disposed on the optical disc 151 corresponding to the waste liquid absorbing assembly 154, a rotating portion capable of rotating relative to the first rack 100 is disposed in the optical disc 151, and the rotating portion has a cup releasing position, and the rotating portion sequentially drives the reaction cup 300 to stop at the light measuring position corresponding to the signal collecting and processing assembly 153, the waste liquid absorbing position corresponding to the waste liquid absorbing hole, and the light measuring position, so as to respectively allow the signal collecting and processing assembly 153 to collect an optical signal emitted by a sample in the reaction cup 300, allow the waste liquid absorbing assembly 154 to absorb liquid in the reaction cup 300, and allow the light measuring gripper assembly 152 to transfer the reaction cup 300 after liquid absorption to the cup losing position 101.

In a specific example, the light measuring disk 151 includes a third base and a third cover plate, the third base and the third cover plate enclose to form a third installation chamber, the rotating portion is disposed in the third chamber, and the light collecting end of the signal collecting and processing assembly 153 is disposed in the third chamber. The waste liquid absorbing assembly 154 is located on the third cover plate, the light measuring position is a light measuring hole position arranged on the third cover plate and is close to the light measuring gripper assembly 152, and the light measuring gripper assembly 152 picks the reaction cup 300 and then places the reaction cup on the cup placing position through the light measuring hole position. The waste liquid absorbing level is a waste liquid absorbing hole disposed on the third cover plate, and the waste liquid absorbing component 154 absorbs the liquid in the reaction cup 300 in the third chamber by passing through the waste liquid absorbing hole.

Wherein, snatch reaction cup 300 and send to putting the cup position through photometry tongs subassembly 152, the signal acquisition and processing assembly can be realized through prior art to preventing reaction cup 300 on the cup position from carrying out the photometry, and it is not repeated here. Waste liquid suction assembly 154 may also be implemented by any conventional technique and will not be described in detail herein.

Further, referring to fig. 4, a waste cup bin for collecting waste reaction cups 300 is provided below the first rack 100 corresponding to the cup discarding position 101.

In another embodiment, referring to fig. 2 and 4, the sampling system 120 includes a sampling needle assembly 121 rotatably disposed on the first rack 100, a reagent disk assembly 122 and a reagent needle assembly 123, the first rack 100 is disposed with a sampling site 124, the sampling needle assembly 121 is disposed between the sampling site 124 and the incubation system 130 and is used for sampling a sample on the sampling site 124 and injecting the sample into the reaction cup 300, the reagent disk assembly 122 is disposed near the incubation system 130 and has a plurality of coaxially disposed annular reagent tube sites for placing reagent tubes, and the reagent needle assembly 123 is disposed between the incubation system 130 and the reagent disk assembly 122 and is used for sampling reagents in the reagent tubes and injecting the reagents into the reaction cup 300.

Wherein, each annular reagent pipe position includes that a plurality of reagent pipe positions and a plurality of reagent pipe positions are the annular setting. The test of a plurality of sample reagents can be completed simultaneously by arranging a plurality of reagent tube positions on the reagent tray, the test is not required to be interrupted due to the fact that the reagents are used up, and the test speed is reduced.

In a practical embodiment, the number of the reagent needle assemblies 123 may be multiple, the number of the sample addition sites 134 is multiple, and each reagent needle assembly 123 correspondingly adds a reagent to the cuvette 300 at one sample addition site 134, so as to satisfy the situation that multiple reagents need to be added, and accelerate the test speed.

In one embodiment, reagent needle assembly 123 rests in a first fixed position corresponding to sample loading position 134 and a second fixed position corresponding to a reagent tube position. Correspondingly, the reagent disk assembly 122 comprises at least one rotating disk, when a plurality of rotating disks are provided, the plurality of rotating disks are coaxially and independently rotatably arranged, one rotating disk corresponds to one reagent needle assembly 123, an annular reagent tube position is arranged on the rotating disk, and the rotating disk drives the reagent tube on the rotating disk to move to a second fixed position corresponding to the reagent needle assembly 123 when rotating.

In one possible embodiment, the reagent disk assembly 122 includes a fourth base and a fourth cover, the rotary disk is rotatably disposed in the fourth base, the fourth cover covers the fourth base, and a fifth driving mechanism for driving the rotary disk to rotate is disposed below the fourth base. In other embodiments, the reagent disk assembly 122 may also include other structures, which are not described in detail herein.

In one possible embodiment, the reagent needle assembly 123 and the sampling needle assembly 121 each include a rotating base rotatably disposed on the first frame 100, a lifting assembly disposed on the rotating base, and a needle tube disposed on the lifting assembly, wherein the rotating base drives the needle tube assembly to rotate, and the lifting assembly drives the needle tube assembly to move up and down so that the needle tube assembly can be inserted into the tube to absorb liquid or be inserted into the tube to inject liquid. Referring to the prior art, in other embodiments, the reagent disk assembly 122 and the sampling needle assembly 121 may further include other structures, which are not described herein.

In another embodiment, referring to fig. 2, 3 and 4, the chemiluminescent immunoassay device 10 further comprises a cup feeding assembly 160 and a rotary gripper assembly 167 disposed on the first rack 100, wherein the cup feeding assembly 160 is disposed on a side of the incubation system 130 away from the reagent disk assembly 122, the rotary gripper assembly 167 is disposed between the incubation system 130 and the cup feeding assembly 160, the cup feeding assembly 160 comprises a cup feeding position 161 loaded with the reaction cup 300, and the rotary gripper assembly 167 is rotatably disposed on the first rack 100 and is used for moving the reaction cup 300 on the cup feeding position 161 to the sample feeding position 134. The layout enables the equipment to be compact in structure and is beneficial to accelerating the testing speed.

Referring to fig. 10, the cup feeding assembly 160 includes a reaction cup bin 162, an upper and lower conveying assembly 163, a chute 164 and a cup feeding tray 166, the reaction cup bin 162 is disposed on the first frame 100, the upper and lower conveying assembly 163 is disposed on the reaction cup bin 162 and is used for conveying the reaction cups 300 at the bottom of the reaction cup bin 162 to an upper outlet of the reaction cup bin 162, a first end of the chute 164 is disposed at the outlet, the other end of the chute 164 is correspondingly provided with the cup feeding tray 166, the cup feeding tray 166 is provided with a cup feeding position 161, and the chute 164 is used for sliding the reaction cups 300 at the outlet to the cup feeding position 161 along the chute 164. Wherein, the bottom of the reaction cup storehouse 162 stores the reaction cup 300, the outlet of the reaction cup storehouse 162 is higher than the cup entering position 161, and the reaction cup 300 slides to the cup entering position 161 along the chute 164 after reaching the outlet.

Further, the cup feeding assembly 160 further comprises a rotating motor 165, a plurality of cup feeding positions 161 arranged along a circular array are arranged on the cup feeding tray 166, and the rotating motor 165 drives the cup feeding tray 166 to rotate and can suspend to a preset position. When the cup feeding tray 166 rotates and hovers to a preset position, the cup feeding position 161 corresponds to the other end of the chute 164 to receive the reaction cup 300 sliding down from the chute 164.

It is understood that the upper and lower conveying assemblies 163 may include a motor and a lifting platform driven by the motor through a belt, and the lifting platform carries the reaction cup, or refer to other structures as long as the reaction cup 300 can be conveyed from the lower portion of the reaction cup warehouse 162 to the upper portion of the reaction cup warehouse 162, and the description thereof is omitted.

In a possible embodiment, referring to fig. 2 and 4, the chemiluminescent immunoassay device 10 further comprises a second rack 200 connected to the first rack 100 and a front rail system disposed on the first rack 100, the second rack 200 is provided with a sample rack placing area 210, a sample rack recovery area 220 and a dispatching component 230, the sample rack placing area 210 is used for storing the sample rack 400 and is disposed on one side of the reagent disk component 122 away from the incubation system 130, the sample rack recovery area 220 is used for recovering the sample rack 400 and is located between the reagent disk component 122 and the sample rack placing area 210;

the front end track system comprises a sample introduction track assembly 171, a track transfer assembly 172 and a recovery track assembly 173, wherein the sample introduction track assembly 171 is used for conveying the sample rack 400 in the sample rack placement area 210 to the sampling position 124, the track transfer assembly 172 is used for conveying the sample rack 400 from the sample introduction track assembly 171 to the recovery track assembly 173, the recovery track assembly 173 is used for conveying the sample rack 400 to a cup returning opening of the sample rack recovery area 220, and the scheduling assembly 230 is arranged on the cup returning opening and used for conveying the sample rack 400 from the recovery track assembly 173 to the sample rack recovery area 220.

The sample injection track assembly 171 and the recovery track assembly 173 may be used for conveying the sample rack 400 thereon by belt conveying, sprocket conveying, and the like, which is not limited herein.

Wherein a plurality of sample tubes may be stored in the sample holder 400.

The embodiment can support automatic sample loading and automatic sample unloading, and the sample quantity is stored greatly, thereby being beneficial to improving the overall testing speed and the processing capacity of the equipment.

In one example, the track transfer assembly 172 includes a track transfer, a sixth drive mechanism that drives the track transfer to move in a first direction that is parallel to the transport direction of the feed track assembly and the recovery track assembly 173, and a seventh drive mechanism that drives the track transfer to move in a second direction that is directed from the first end of the feed track assembly to the first end of the recovery track assembly 173 to transport the sample rack 400 from the feed track assembly to the recovery track assembly 173. The sixth drive mechanism may be a belt conveyor mechanism and the seventh drive mechanism may be a linear motor.

It is understood that the tracking assembly 172 may also include other structures, and is not limited thereto.

As an example, the dispatching assembly 230 includes a dispatching robot that grabs the sample rack 400 and transports the sample rack 400 to a designated location, and in other embodiments, the dispatching assembly 230 may include other structures as well, without limitation.

By the present embodiment, it is possible to realize the automatic feeding of the sample rack 400 and the automatic recovery of the sample rack 400 by the chemiluminescent immunoassay device. The sample rack placing area 210 and the sample rack recovery area 220 can both be used for placing a plurality of sample racks 400, which is helpful for realizing the simultaneous test of a plurality of samples.

In one embodiment, referring to fig. 2 and 4, the sample injection track assembly 171 comprises a conventional track assembly 1711 and an emergency track assembly 1712, an emergency insertion assembly 240 is disposed on the second rack 200 corresponding to the emergency track assembly 1712, a sampling site 124 is disposed on each of a first end of the conventional track assembly 1711 and a first end of the emergency track assembly 1712, a second end of the conventional track assembly 1711 corresponds to the sample outlet of the sample rack placement area 210 for transporting the sample rack 400 in the sample rack placement area 210 to the first sampling site, a second end of the emergency track assembly 1712 corresponds to the emergency insertion assembly 240 for transporting the sample rack 400 on the emergency insertion assembly 240 to the second sampling site, and the track transfer assembly 172 is selectively movable to the first end of the conventional track assembly 1711, the first end of the emergency track assembly 1712, and the first end of the recovery track assembly 173.

In the present embodiment, two sample rack 400 conveying rails are provided, which can satisfy the conventional test and the emergency test.

The emergency track assembly 1712 and the conventional track assembly 1711 may transport the sample rack 400 thereon by means of belt conveying, sprocket conveying, and the like, which is not limited herein.

Illustratively, the emergency insertion assembly 240 includes a slide rail disposed on the second rack 200 and a slot slidably disposed on the slide rail for receiving the sample rack 400 requiring emergency testing, the slot being extractable and insertable along the slide rail. When the presence of a sample rack 400 within the slot is detected, the dispatch robot transports the sample rack 400 onto the emergency track assembly 1712. In other embodiments, emergency insert assembly 240 may also include other structures, which are not described in detail herein.

Further, referring to fig. 2, 3 and 4, a scanning device 260 is disposed at the sample outlet of the sample rack placement area 210, the scanning device 260 is connected to the control system 250, and the scanning device 260 is configured to scan information of sample tubes on the sample rack 400, so that the control system 250 correspondingly stores the test results of the sample tubes with the information of the sample tubes. For example, the dispatching robot may grab the sample rack 400 and sequentially pass the sample tubes on the sample rack 400 through the scanning device 260 in a certain direction, so that the information of the sample tubes on the sample tubes is acquired by the scanning device 260. Similarly, the sample tube information on the sample rack 400 on the emergency insertion assembly 240 may be scanned.

The arrangement of the scanning device 260 is helpful for realizing the automatic matching of the test result and the test sample, and the intelligence of the equipment is improved.

In one embodiment, referring to fig. 11 and 12, the chemiluminescent immunoassay device 10 comprises a second rack 200 and a plurality of first racks 100, the plurality of first racks 100 are connected in sequence, the second rack 200 is connected to one side of the plurality of racks, front end rail assemblies among the plurality of first racks 100 correspond, and a rail changing assembly 172 can communicate with the sample feeding rail assemblies 171 on two adjacent first racks 100 and the recovery rail assemblies 173 on two adjacent first racks 100.

Through the embodiment, the plurality of first racks 100 can be connected, the test quantity of the whole equipment is expanded by multiple levels, and the test speed is further accelerated.

Illustratively, referring to fig. 11, the first racks 100 are connected to each other by a cascade connection block 500. One end of the cascade connection block 500 is fastened to one of the two adjacent first racks 100, and the other end is fastened to the other of the two adjacent first racks 100, thereby preventing the first racks 100 from being unsmooth in engagement.

Referring to fig. 2, 4 and 13, the test procedure of the chemiluminescent immunoassay device according to one embodiment of the present application is as follows: starting the analyzer, starting the whole analysis process by operating the computer, conveying the reaction cup 300 to the cup feeding position 161 at position d by the cup feeding assembly 160, placing the reaction cup 300 from the cup feeding position 161 at position d to the sample feeding position at position e by the rotating gripper assembly 167 along a preset movement track, conveying the reaction cup 300 to the sample feeding position 134 at position f and/or the sample feeding position 134 at position g by the rotating sample tray 132, sucking a reagent from the reagent tray by the reagent needle assembly 123 and injecting the reagent into the reaction cup 300, conveying the reaction cup 300 to the sample feeding position 134 at position c by the rotating sample tray 132, sucking a sample from the sample sampling position by the sampling needle assembly 121, conveying the reaction cup 300 to the sample feeding position 134 at position c along the preset movement track and injecting the sample into the reaction cup 300, conveying the reaction cup 300 to the sample feeding position 134 at position m by the rotating sample tray 132, conveying the reaction cup 300 to the incubation position 135 at position m by the blending gripper assembly 131, incubating for a period of time, the incubation disc 133 transports the reaction cup 300 to h, and the cleaning gripper assembly 141 grabs and transports the reaction cup 300 to i of the cleaning disc 144 along a preset motion track.

When the sample reagent in the reaction cup only needs to be cleaned in one step, the cleaning position 143 corresponding to the first cleaning component at the position i is arranged, when the sample reagent in the reaction cup needs to be cleaned in two steps, the cleaning grabbing component 141 grabs the reaction cup 300 along a preset motion track and conveys the reaction cup 300 to the cleaning position 143 corresponding to the second cleaning component at the position i of the cleaning disc 144, when the cleaning disc 144 rotates, the reaction cup 300 passes through the uniform mixing component 145, and the liquid suction and injection component 146 is uniformly mixed and cleaned;

on one hand, the cleaning disc 144 drives the reaction cup 300 of the first cleaning assembly to move to the position below the substrate assembly 142 to inject substrates for mixing, after mixing, the cleaning pot 24 rotates to convey the reaction cup 300 to the position j, the photometric gripper assembly 152 grabs the reaction cup 300 along a preset movement track and conveys the reaction cup 300 to the position k of the photometric disk 151 to perform photometry, after photometry is completed, the photometric disk 151 conveys the reaction cup 300 to the position l below the waste liquid suction assembly, after the waste liquid suction assembly 154 sucks liquid in the reaction cup 300, the photometric disk 151 conveys the reaction cup 300 back to the position k, and the photometric gripper assembly 151 grabs the reaction cup 300 to the cup losing position 101 to be lost into a waste cup bin. And displaying the test result by the computer, and finishing the whole test process.

On the other hand, the cleaning disc 144 drives the cuvette 300 of the first cleaning assembly to move back to the position i when rotating, the cleaning gripper assembly 141 grips the cuvette 300 from the cleaning position corresponding to the second cleaning assembly at the position i and conveys the cuvette to the sample loading position 134 at the position h along a preset movement track, the sample disc 132 rotates to convey the cuvette 300 to the sample loading position 134 at the position f and/or the sample loading position 134 at the position g, and the subsequent steps are executed.

The above description is only exemplary of the present application and should not be taken as limiting the present application, as any modification, equivalent replacement, or improvement made within the spirit and principle of the present application should be included in the protection scope of the present application.

Claims

1. A chemiluminescent immunoassay device comprising a first housing (100), a sampling system (120) disposed on the first housing (100), an incubation system (130), and a washing system (140);

the incubation system (130) comprises a blending hand grip assembly (131), a sample disc (132) and an incubation disc (133), wherein the sample disc (132) is provided with a plurality of sample adding positions (134) for placing reaction cups (300), the sampling system (120) is used for injecting samples and/or reagents into the reaction cups (300) positioned on the sample adding positions (134), the incubation disc (133) is provided with a plurality of incubation positions (135), and the blending hand grip assembly (131) is used for transferring the reaction cups (300) injected with the samples and/or the reagents on the sample adding positions (134) to the incubation positions (135) for incubation after blending operation;

the cleaning system (140) comprises a cleaning gripper assembly (141), a substrate assembly (142), and a first cleaning assembly and a second cleaning assembly which are arranged on the first frame (100) and can clean and separate the reaction cups (300), wherein the first cleaning assembly and the second cleaning assembly respectively comprise a plurality of cleaning positions (143), the cleaning gripper assembly (141) is used for transferring the reaction cups (300) positioned at the incubation positions (135) to the cleaning positions (143) and transferring the reaction cups (300) cleaned and separated on the first cleaning assembly to the sample adding position (134), and the substrate assembly (142) is used for adding substrates into the reaction cups (300) cleaned and separated on the second cleaning assembly.

2. The apparatus of claim 1, wherein the incubation system (130) further comprises a first base and a first cover enclosing a first mounting chamber, the sample tray (132) and the incubation tray (133) being coaxially and independently rotatably disposed within the first mounting chamber; set up on the first apron and shift hole (136) and loading hole (137), shift hole (136) and correspond and expose at least one loading position (134) and at least one incubate position (135), loading hole (137) correspond and expose at least one loading position (134), sampling system (120) pass through loading hole (137) pour into sample and/or reagent into reaction cup (300), mixing tongs subassembly (131) are close to shift hole (136) set up in on the first apron and still be used for with shift hole (136) expose reaction cup (300) on loading position (134) carry out the mixing operation after shift to shift hole (136) expose incubate position (135).

3. The apparatus according to claim 1, wherein the cleaning system (140) further comprises a cleaning tray (144), the cleaning gripper assembly (141) and the substrate assembly (142) are disposed on the upper side of the cleaning tray (144), the first cleaning assembly and the second cleaning assembly each comprise a cleaning pan rotatably disposed in the cleaning tray (144) and having a plurality of cleaning positions (143) arranged in a ring shape, a mixing assembly disposed on the upper side of the cleaning tray (144) and used for mixing solid and liquid in the reaction cups (300) on the cleaning positions (143), a magnetic separation assembly disposed on the cleaning tray (144) and used for adsorbing and separating solid and liquid in the reaction cups (300), and a liquid injection assembly disposed on the cleaning tray (144) and used for injecting, absorbing and cleaning the reaction cups (300).

4. The chemiluminescent immunoassay device according to any one of claims 1 to 3, further comprising an optical detection system (150) disposed on the first rack (100), wherein the optical detection system (150) comprises an optical measurement disc (151), an optical measurement hand grip assembly (152) and a signal acquisition and processing assembly (153), wherein a cup placing position is disposed in the optical measurement disc (151), the optical measurement hand grip assembly (152) is used for transferring the reaction cup (300) filled with the substrate to the cup placing position, and the signal acquisition and processing assembly (153) is used for acquiring and processing an optical signal emitted by a sample in the reaction cup (300) on the cup placing position.

5. The apparatus according to claim 4, wherein the first rack (100) further comprises a cup losing position (101), the optical detection system (150) further comprises a waste liquid absorbing assembly (154) disposed on the optical disc (151), the optical disc (151) further comprises a waste liquid absorbing hole disposed corresponding to the waste liquid absorbing assembly (154), the optical disc (151) further comprises a rotating portion rotatable with respect to the first rack (100), the rotating portion has the cup releasing position, and the rotating portion sequentially drives the reaction cup (300) to stop at the light measuring position corresponding to the signal collecting and processing assembly (153), the waste liquid absorbing position corresponding to the waste liquid absorbing hole, and the light measuring position, respectively, for the signal collecting and processing assembly (153) to collect the optical signal emitted by the sample in the reaction cup (300), for the waste liquid absorbing assembly (154) to absorb the liquid in the reaction cup (300), And the photometric gripper assembly (152) is used for transferring the reaction cup (300) after liquid absorption to the cup losing position (101).

6. The apparatus according to any of the claims 1 to 3, wherein the sampling system (120) comprises a sampling needle assembly (121), a reagent disk assembly (122) and a reagent needle assembly (123) rotatably arranged on the first rack (100), a sampling position (124) is arranged on the first frame (100), the sampling needle assembly (121) is arranged between the sampling position (124) and the incubation system (130) and is used for collecting a sample on the sampling position (124) and injecting the sample into a reaction cup (300), the reagent disk assembly (122) is disposed proximate to the incubation system (130) and has a plurality of coaxially disposed annular reagent tube sites for reagent tube placement, the reagent needle assembly (123) is disposed between the incubation system (130) and the reagent tray assembly (122) and is used to collect and inject reagents within the reagent tubes into a reaction cup (300).

7. The apparatus of claim 6, further comprising a cup feeding assembly (160) and a rotating gripper assembly (167) disposed on the first rack (100), wherein the cup feeding assembly (160) is disposed on a side of the incubation system (130) away from the reagent disk assembly (122), the rotating gripper assembly (167) is disposed between the incubation system (130) and the cup feeding assembly (160), the cup feeding assembly (160) comprises a cup feeding position (161) loaded with a reaction cup (300), and the rotating gripper assembly (167) is rotatably disposed on the first rack (100) and is used for transferring the reaction cup (300) on the cup feeding position (161) to the sample feeding position (134).

8. The apparatus of claim 7, further comprising a second rack (200) connected to the first rack (100) and a front end rail system disposed on the first rack (100), wherein the second rack (200) is provided with a sample rack placement area (210), a sample rack retrieval area (220) and a dispatching component (230), the sample rack placement area (210) is used for storing a sample rack (400) and is disposed on a side of the reagent disk assembly (122) away from the incubation system (130), the sample rack retrieval area (220) is used for retrieving the sample rack (400) and is disposed between the reagent disk assembly (122) and the sample rack placement area (210);

the front end track system comprises a sample feeding track assembly (171), a track changing assembly (172) and a recovery track assembly (173), wherein the sample feeding track assembly (171) is used for conveying the sample rack (400) in the sample rack placing area (210) to the sampling position (124), the track changing assembly (172) is used for conveying the sample rack (400) from the sample feeding track assembly (171) to the recovery track assembly (173), the recovery track assembly (173) is used for conveying the sample rack (400) to a cup returning opening of the sample rack recovery area (220), and the scheduling assembly (230) is arranged on the cup returning opening and is used for transferring the sample rack (400) from the recovery track assembly (173) to the sample rack recovery area (220).

9. The apparatus according to claim 8, wherein the sample injection track assembly (171) comprises a regular track assembly (1711) and an emergency track assembly (1712), the second rack (200) being provided with an emergency insertion assembly (240) corresponding to the emergency track assembly (1712), the regular track assembly (1711) being provided with the sampling sites (124) at a first end thereof and the emergency track assembly (1712) being provided with the sample outlets at a first end thereof, the regular track assembly (1711) being provided with the sample outlets at a second end thereof corresponding to the sample rack placement area (210) for transporting the sample racks (400) in the sample rack placement area (210) to the corresponding sampling sites (124), the emergency track assembly (1712) being provided with the sample outlets at a second end thereof corresponding to the emergency insertion assembly (240) for transporting the sample racks (400) on the emergency insertion assembly (240) to the corresponding sampling sites (124), the derailment assembly (172) is selectively movable to a first end of the normal track assembly (1711), a first end of the emergency track assembly (1712), and a first end of the recovery track assembly (173).

10. The apparatus according to claim 8, comprising a second rack (200) and a plurality of the first racks (100), wherein the plurality of the first racks (100) are connected in sequence, and the second rack (200) is connected to one side of the plurality of the racks, the front rail assemblies between the plurality of the first racks (100) correspond, and the rail transfer assembly (172) can communicate the sample rail assemblies (171) on two adjacent first racks (100) and the recovery rail assemblies (173) on two adjacent first racks (100).