CN111772776A - Radio frequency and chemical integrated ablation device - Google Patents
Radio frequency and chemical integrated ablation device Download PDFInfo
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- CN111772776A CN111772776A CN202010686972.6A CN202010686972A CN111772776A CN 111772776 A CN111772776 A CN 111772776A CN 202010686972 A CN202010686972 A CN 202010686972A CN 111772776 A CN111772776 A CN 111772776A
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- 239000000126 substance Substances 0.000 title claims abstract description 129
- 238000002679 ablation Methods 0.000 title claims abstract description 112
- 238000007674 radiofrequency ablation Methods 0.000 claims abstract description 122
- 238000002347 injection Methods 0.000 claims abstract description 72
- 239000007924 injection Substances 0.000 claims abstract description 72
- 230000005540 biological transmission Effects 0.000 claims abstract description 62
- 238000001816 cooling Methods 0.000 claims abstract description 18
- 230000010354 integration Effects 0.000 claims abstract description 8
- 239000010410 layer Substances 0.000 claims description 37
- 239000000110 cooling liquid Substances 0.000 claims description 32
- 239000007788 liquid Substances 0.000 claims description 22
- 238000002955 isolation Methods 0.000 claims description 19
- 239000011247 coating layer Substances 0.000 claims description 16
- 239000012530 fluid Substances 0.000 claims description 15
- 229940126585 therapeutic drug Drugs 0.000 claims 2
- 238000011282 treatment Methods 0.000 abstract description 12
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- 238000002844 melting Methods 0.000 abstract description 3
- 230000008018 melting Effects 0.000 abstract description 3
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 3
- 239000002826 coolant Substances 0.000 description 5
- 239000002246 antineoplastic agent Substances 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 229940044683 chemotherapy drug Drugs 0.000 description 3
- 239000012809 cooling fluid Substances 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 239000013043 chemical agent Substances 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
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- 238000007789 sealing Methods 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010028851 Necrosis Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000011298 ablation treatment Methods 0.000 description 1
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- 230000037431 insertion Effects 0.000 description 1
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/06—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating caused by chemical reaction, e.g. moxaburners
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00994—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound
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Abstract
The invention discloses a radio frequency and chemical integrated ablation device, which comprises a transmission catheter, wherein a near-end interface for connecting a radio frequency ablation controller or/and a chemical ablation injector is arranged at the near end of the transmission catheter, a radio frequency ablation electrode for radio frequency ablation and an injection head for chemical ablation are arranged at the far end of the transmission catheter, an electric connector for connecting the radio frequency ablation controller and the radio frequency ablation electrode is arranged in the transmission catheter, a hollow pipe for connecting the chemical ablation injector and the injection head is also arranged in the transmission catheter, and the transmission catheter and the hollow pipe are integrated. Through the ablation device that this integration combines, can realize carrying out radio frequency ablation and chemical ablation simultaneously, also can carry out radio frequency ablation and chemical ablation by the timesharing, can also carry out treatments such as cooling, disinfection at the ablation in-process, be favorable to melting the improvement and the promotion of effect, can also reduce cost and treatment risk.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a radio frequency and chemical integrated ablation device.
Background
The radio frequency ablation is an interventional technique of delivering a radio frequency ablation catheter to a specific position through a blood vessel, and releasing radio frequency current to cause coagulation necrosis of local nerves and tissues of the specific position so as to block a conduction bundle or an origin point. Because the radio frequency current has the advantages of small damage range and no harm to organisms, the radio frequency current is widely applied to treating arrhythmia, hypertension, diabetes, cancer tumor and the like.
Under the condition of the prior art, the treatment effect of single radiofrequency ablation is not ideal for some complicated disease focus parts, and further chemical ablation is often needed for treatment. However, under the current conditions, the two ablation treatment processes need to be performed separately, and need to enter the blood vessel of the human body through the catheter respectively, and when the lesion is reached, obviously, the method not only brings treatment pain to the patient, but also can enhance treatment cost and treatment risk. Therefore, there is a need to develop a study that combines radiofrequency ablation with chemical ablation.
Disclosure of Invention
The invention mainly solves the technical problem of providing a radio frequency and chemical integrated ablation device, and solves the problems that integrated equipment is lacked in the prior art, and radio frequency ablation and chemical ablation can only be independently and separately carried out.
In order to solve the technical problems, one technical scheme adopted by the invention is to provide a radio frequency and chemical integrated ablation device, which comprises a transmission catheter, wherein a near-end interface for connecting a radio frequency ablation controller or/and a chemical ablation injector is arranged at the near end of the transmission catheter, a radio frequency ablation electrode for radio frequency ablation and an injection head for chemical ablation are arranged at the far end of the transmission catheter, an electric connector for connecting the radio frequency ablation controller and the radio frequency ablation electrode is arranged in the transmission catheter, a hollow tube for connecting the chemical ablation injector and the injection head is also arranged in the transmission catheter, and the transmission catheter and the hollow tube are integrated.
Preferably, the hollow pipe is arranged outside the transmission pipe, the outer layer of the transmission pipe is a coating layer, the electric connector is sealed inside the coating layer, and the surface of the coating layer is further combined with the surface of the outer layer of the hollow pipe into a whole, so that a double-pipe structure body is formed in which the outer surface of the transmission pipe and the outer surface of the hollow pipe are combined into a whole.
Preferably, the proximal interface comprises a radiofrequency ablation proximal interface for connecting the delivery catheter and a chemical ablation proximal interface for hermetically connecting the hollow tube.
Preferably, the hollow pipe is arranged inside the transmission conduit, the outer layer of the transmission conduit is a coating layer, the center of the hollow pipe is sleeved inside the coating layer, an isolation layer is arranged between the coating layer and the hollow pipe, and the electric connector is arranged on the isolation layer, so that an integrated structure body is formed in which the hollow pipe and the electric connector are sleeved inside the transmission conduit
Preferably, a medical liquid flow pipe is further arranged in the isolation layer, the medical liquid flow pipe extends to the radiofrequency ablation electrode, and the radiofrequency ablation electrode is provided with a flow guide hole and is communicated with the medical liquid flow pipe.
Preferably, still be provided with two piece at least coolant liquid flow pipes in the barrier layer, coolant liquid flow pipe extends to the radiofrequency ablation electrode, the inside or the medial surface of radiofrequency ablation electrode is provided with the cooling pipe network, the both ends of cooling pipe network are connected with two coolant liquid flow pipes respectively, constitute cooling circuit through two coolant liquid flow pipes and cooling pipe network from this, lower the temperature to the radiofrequency ablation electrode through pouring into the coolant liquid into cooling circuit.
Preferably, the radio frequency ablation electrode is a hollow cylinder, one end of the radio frequency ablation electrode is hermetically combined with the transmission catheter, the other end of the radio frequency ablation electrode is of an arc-shaped structure, and an injection hole is formed in the center of the arc; the injection head is arranged inside the radiofrequency ablation electrode, an expansion body is further arranged inside the injection head, and the expansion body can push the needle head of the injection head to be exposed out of the injection hole after being inflated.
Preferably, the proximal interface comprises a medical liquid input port which is correspondingly hermetically connected with a medical liquid flow pipe in the isolation layer, and the radio frequency ablation controller correspondingly comprises a medical liquid input body which is correspondingly inserted into the medical liquid input port and hermetically connected with the medical liquid input port.
Preferably, the near-end interface comprises a cooling liquid input port and a cooling liquid output port which are respectively and correspondingly hermetically connected with the two liquid flow pipes in the isolation layer, and the radio frequency ablation controller correspondingly comprises a cooling liquid input body and a cooling liquid output body which are respectively and correspondingly hermetically inserted and connected with the cooling liquid input port and the cooling liquid output port.
Preferably, the proximal interface comprises a chemical injection port and a gas injection port, a chemical pipeline and a gas pipeline are arranged in the hollow tube, the chemical injection port is hermetically connected with the chemical pipeline, the chemical ablation injector correspondingly comprises a chemical injection body, and the chemical injection body is inserted into the chemical injection port and then injects a chemotherapeutic drug into the chemical pipeline so as to inject a chemotherapeutic drug into the distal injection head; the gas injection port is hermetically connected with a gas pipeline, the gas pipeline is also communicated with the expansion body, the chemical ablation injector correspondingly comprises a gas injection body, and the gas injection body is inserted into the gas injection port and then injects gas into the gas pipeline so as to inject gas into the expansion body at the far end.
The invention has the beneficial effects that: the invention discloses a radio frequency and chemical integrated ablation device, which comprises a transmission catheter, wherein a near-end interface for connecting a radio frequency ablation controller or/and a chemical ablation injector is arranged at the near end of the transmission catheter, a radio frequency ablation electrode for radio frequency ablation and an injection head for chemical ablation are arranged at the far end of the transmission catheter, an electric connector for connecting the radio frequency ablation controller and the radio frequency ablation electrode is arranged in the transmission catheter, a hollow pipe for connecting the chemical ablation injector and the injection head is also arranged in the transmission catheter, and the transmission catheter and the hollow pipe are integrated. Through the ablation device that this integration combines, can realize carrying out radio frequency ablation and chemical ablation simultaneously, also can carry out radio frequency ablation and chemical ablation by the timesharing, can also carry out treatments such as cooling, disinfection at the ablation in-process, be favorable to melting the improvement and the promotion of effect, can also reduce cost and treatment risk.
Drawings
FIG. 1 is a schematic view of a delivery catheter and hollow tube assembly according to one embodiment of the integrated RF and chemical ablation device of the present invention;
FIG. 2 is a schematic diagram of the RF ablation controller assembly of one embodiment of the RF and chemical integrated ablation device of the present invention;
fig. 3 is a schematic diagram of the chemical ablation controller of an embodiment of the rf and chemical integrated ablation device according to the present invention.
FIG. 4 is a schematic cross-sectional view of a delivery catheter and hollow tube of one embodiment of a radio frequency and chemical integrated ablation device in accordance with the invention;
FIG. 5 is a cross-sectional view of one embodiment of the RF and chemical combination ablation device of the present invention with the needle retracted within the injection head;
FIG. 6 is a cross-sectional view of a needle extending out of the injection head of one embodiment of the integrated radio frequency and chemical ablation device according to the invention;
FIG. 7 is a schematic cross-sectional view of an expansion body of an embodiment of the integrated RF and chemical ablation device of the present invention;
FIG. 8 is a schematic view of a proximal interface of an embodiment of the integrated RF and chemical ablation device in accordance with the present invention;
FIG. 9 is a schematic view of the delivery catheter and hollow tube of another embodiment of the integrated RF and chemical ablation device of the present invention;
FIG. 10 is a schematic cross-sectional view of a delivery catheter and hollow tube of another embodiment of a radio frequency and chemical integrated ablation device in accordance with the invention;
FIG. 11 is a cross-sectional view of a radio frequency ablation electrode of another embodiment of a radio frequency and chemical integrated ablation device according to the invention;
FIG. 12 is a schematic cross-sectional view of a radio frequency ablation electrode of another embodiment of a radio frequency and chemical integrated ablation device in accordance with the invention;
FIG. 13 is a schematic view of a proximal interface of another embodiment of a radio frequency and chemical integrated ablation device in accordance with the invention;
fig. 14 is a schematic diagram of the rf ablation controller of another embodiment of the rf and chemical integrated ablation device in accordance with the invention.
Detailed Description
In order to facilitate an understanding of the invention, the invention is described in more detail below with reference to the accompanying drawings and specific examples. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It is to be noted that, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
As shown in fig. 1 to 3, the radiofrequency and chemical integrated ablation device comprises a transmission catheter 1, a proximal interface 4 for connecting a radiofrequency ablation controller 2 or/and a chemical ablation injector 3 is arranged at the proximal end of the transmission catheter 1, and a radiofrequency ablation electrode 5 for radiofrequency ablation and an injection head 6 for chemical ablation are arranged at the distal end of the transmission catheter 1.
Referring to fig. 4, fig. 4 is a schematic cross-sectional view of the transfer duct 1 and the hollow tube 8. The transmission catheter 1 comprises an electric connector 7 which is connected with the radio frequency ablation controller 2 and the radio frequency ablation electrode 5. Also comprises a hollow tube 8 for connecting the chemical ablation injector 3 and the injection head 6, and the transmission catheter 1 and the hollow tube 8 are integrated.
In fig. 4, the hollow pipe 8 is disposed outside the transmission pipe 1, the outer layer of the transmission pipe 1 is a coating layer 101, the electric connector 7 is enclosed inside the coating layer 101, and the surface of the coating layer 101 is also integrated with the surface of the outer layer of the hollow pipe 8, thereby forming a double-pipe structure in which the outer surface of the transmission pipe 1 and the outer surface of the hollow pipe 8 are integrated.
Inside the covering layer 101, the electric connector 7 includes two independent connection cables, a positive connection cable 71 and a negative connection cable 72. The two connecting cables are respectively connected with the positive and negative wiring terminals of the radiofrequency ablation electrode 5. The outer layer of at least one of the two connecting cables is wrapped by an insulating layer 9, so that the two connecting cables are prevented from being directly contacted with each other in the wrapping layer 101 to cause short circuit.
More preferably, the hard elastic metal strip 10 having an arc-surface shape is further provided inside the coating layer 101 and extends in the axial direction of the transmission duct 1, whereby the toughness and rigidity of the entire transmission duct 1 can be improved and the bending resistance can be enhanced.
Further preferably, an expansion body is further arranged in the injection head, the expansion body is hermetically connected with the hollow tube, and when no gas is injected into the expansion body through the hollow tube, the expansion body is in a contraction state and is not in contact with the outer surface of the radiofrequency ablation electrode. Thus, the heat generated when the RF ablation electrode performs RF ablation does not affect the expansion body. Preferably, when gas is injected into the expansion body, the expansion body expands forwards to extend and expose the injection head at the front end.
Specifically, fig. 5 and 6 are combined. Fig. 5 is a cross-sectional view of the needle retracted within the head and fig. 6 is a cross-sectional view of the needle extended out of the head. The hollow tube 8 is hermetically connected with the injection head 6. Inside the hollow tube 8, a chemical pipe 81 and a gas pipe 82 are provided. An expansion body 62 is also arranged in the injection head 6, and when no gas is injected into the expansion body 62 through the gas pipeline 82, the expansion body 62 is in a contraction state and is not in contact with the outer surface of the radio frequency ablation electrode 5. Thus, the heat generated when the RF ablation electrode 5 performs RF ablation does not affect the expansion body 62. Preferably, when gas is injected into inflatable body 62, inflatable body 62 expands forward and pushes needle 61 out of circular hole 66 of syringe head 6.
It can be seen that inflatable body 62 is held in place by a mounting bracket 64, which mounting bracket 64 is concave in cross-section and includes a bottom wall and side walls. The end of the expansion body 62 far away from the needle 61 is fixed on the bottom wall of the fixing frame 64, and the end close to the needle 61 is connected with the moving plate 63. The upper and lower sides of the moving plate 63 are provided with a projection 631, the side wall of the fixing frame 64 is correspondingly provided with a sliding slot 65, and the projection 631 is positioned in the sliding slot 65 and can slide in the sliding slot 65.
Preferably, referring to fig. 7, the expansion body 62 is circular in cross section and has a through hole 621 for the chemical conduit 81 to pass through, and the chemical conduit 81 also passes through the moving plate 63 and communicates with the needle 61 fixed on the moving plate 63.
The gas pipeline 82 is communicated with the expansion body 62, when the gas pipeline 82 is used for aerating the expansion body 62, the expansion body 62 expands in volume to push the moving plate 63 to move forwards, the needle 61 extends out of the injection head 6, and the chemical agent can be injected into the needle 61 through the chemical pipeline 81 to perform ablation. After chemical ablation, when the air duct 82 is exhausted, the volume of the expansion body 62 is reduced to pull the moving plate 63 to move backwards, and the needle 61 is retracted in the injection head 6.
As shown in fig. 8, it is further preferred that the proximal interface 4 comprises a radiofrequency ablation proximal interface for connecting the electrical connector 7 within the transmission catheter 1, the radiofrequency ablation proximal interface comprising a positive interface 41 and a negative interface 42. The radio frequency ablation proximal end interface is used for electrically connecting with the radio frequency ablation controller 2 in fig. 2. And a chemical ablation proximal interface for hermetically connecting the hollow tube 8, wherein the chemical ablation proximal interface comprises a chemical pipeline interface 43 and a gas pipeline interface 44, and is connected with the chemical ablation injector 3 through a chemical general interface 33 in fig. 3. The chemical ablation injector 3 includes a chemical injector 31 and a gas injector 32, which are respectively in communication with a chemical conduit interface 43 and a gas conduit interface 44.
It can be seen that the radio frequency ablation proximal interface and the chemical ablation proximal interface are two independent interfaces, and are respectively connected with the radio frequency ablation controller 2 and the chemical ablation injector 3. Therefore, the radio frequency ablation and the chemical ablation can be respectively and independently carried out, for example, the radio frequency ablation is carried out firstly, and then the chemical ablation is carried out, but the mode of respectively and independently carrying out the ablation does not need to take out the integrated channel connecting pipe, and under the condition that the transmission catheter and the hollow pipe are not taken out after being inserted into a human body along a blood vessel, the radio frequency ablation is carried out firstly and then the chemical ablation is carried out, or the chemical ablation is carried out firstly and then the radio frequency ablation is carried out. The two ablation modes can be simultaneously or synchronously carried out according to the treatment requirement, namely, the radiofrequency ablation and the chemical ablation are carried out simultaneously, so that the two modes can be synchronously carried out.
Preferably, as another embodiment of the present invention. Combine fig. 9 and 10. The hollow tube 8 is arranged inside the transmission conduit 1, the outer layer of the transmission conduit 1 is a coating layer 101, the hollow tube 8 is sleeved inside the coating layer 101, an isolation layer 11 is arranged between the coating layer 101 and the hollow tube 8, and the electric connector 7 is arranged on the isolation layer 11. This forms an integrated structure in which the hollow tube 8 and the electric connector 7 are fitted inside the transmission pipe 1. The isolation layer 11 here can be filled with a soft material.
Preferably, the electrical connector 7 comprises two separate connection cables, a positive connection cable 71 and a negative connection cable 72. The two connecting cables are respectively connected with the positive pole and the negative pole of the radio frequency ablation electrode 5.
Preferably, the isolating layer 11 is further provided with a hard elastic metal strip 10 in an arc shape and extends in the axial direction of the transmission duct 1, so that the toughness and rigidity of the entire transmission duct 1 can be improved and the bending resistance can be enhanced.
Preferably, in conjunction with fig. 11, fig. 11 is a cross-sectional view of the radiofrequency ablation electrode 5. The isolation layer 11 is also internally provided with a medical liquid flow pipe 12, the medical liquid flow pipe 12 extends to the radio frequency ablation electrode 5, the radio frequency ablation electrode 5 is provided with a flow guide hole 51 and is communicated with the medical liquid flow pipe 12, and the medical liquid flow pipe is used for injecting physiological saline or other liquid medicines for diminishing inflammation, sterilizing and resisting virus during radio frequency ablation. In fig. 9, the medical fluid flow tube 12 has two.
Preferably, in conjunction with fig. 12. Fig. 12 is a schematic cross-sectional view of the radio frequency ablation electrode 5. At least two cooling liquid flow pipes 13 are further arranged in the isolation layer 11, the cooling liquid flow pipes 13 extend to the radio frequency ablation electrode 5, a cooling pipe network 52 is arranged inside or on the inner side surface of the radio frequency ablation electrode 5, two ends (53 and 54) of the cooling pipe network 52 are respectively communicated with the two cooling liquid flow pipes 13, therefore, a cooling loop is formed by the two cooling liquid flow pipes 13 and the cooling pipe network 52, and cooling liquid is injected into the cooling liquid flow pipes 13 to cool the radio frequency ablation electrode 5.
Preferably, in fig. 11, the rf ablation electrode 5 is a hollow cylinder, one end of which is hermetically combined with the transmission catheter 1, and the other end of which is of an arc-shaped structure, and an injection hole 55 is formed in the center of the arc. The injection head 6 is arranged inside the radiofrequency ablation electrode 5, an expansion body 62 is further arranged inside the injection head 6, and after the expansion body 62 is inflated, a needle 61 of the injection head 6 can be pushed to expose out of the injection hole 55.
Specifically, in fig. 11, the front end of the injection head 6 is a planar structure, which is convenient for being installed in the radiofrequency ablation electrode 5. The radiofrequency ablation electrode 5 is in a hollow cylindrical shape, and a cavity 56 for accommodating the chemical ablation injection head 6 is arranged inside the radiofrequency ablation electrode 5. The cavity 56 extends from the center of the end of the radiofrequency ablation electrode 5 to the head of the radiofrequency ablation electrode 5, the head of the radiofrequency ablation electrode 5 is of an arc-shaped structure, an injection hole 55 is formed in the center of the arc, and the injection hole 55 is communicated with the cavity 56.
A chemical ablation injection head 6 is arranged in the cavity 56, a needle 61 for connecting with a chemical pipeline 81 and an expansion body 62 for connecting with a gas pipeline 82 are arranged in the chemical ablation injection head 6, and the needle 61 is also connected with the expansion body 62. When no gas is injected into the expansion body 62 through the gas conduit 82, the expansion body 62 is in a contracted state and does not contact the outer surface of the radiofrequency ablation electrode 5. Thus, the heat generated when the RF ablation electrode 5 performs RF ablation does not affect the expansion body 62. When gas is injected into the expansion body 62 through the gas pipeline 82, the expansion body 62 expands to push the needle 61 forward to extend out of the injection hole 55, and then chemical agent can be injected into the needle 61 through the chemical pipeline 81 for ablation. After chemical ablation, when the gas pipeline 82 is exhausted outwards, the volume of the expansion body 62 is reduced, and the needle 61 is pulled to be contracted in the radio frequency ablation electrode 5.
Preferably, expansion body 62 pushes needle 61 to expose injection hole 55 by moving plate 63, the principle of which is identical to that expressed in fig. 5 and 6 and will not be described herein.
Preferably, in the embodiment shown in fig. 1, the radiofrequency ablation electrode 5 is also provided with a diversion hole 51 and a cooling pipe network 52, and the delivery catheter 1 is correspondingly provided with a medical fluid flow pipe 12 and a cooling fluid flow pipe 13.
Preferably, as shown in fig. 13. The proximal interface 4 comprises two rf electrode terminals electrically connected to two independent connection cables in the isolation layer 11, respectively. The two radio frequency electrode ends are respectively arranged in two radio frequency electrode holes, namely a radio frequency positive electrode hole 41 and a radio frequency negative electrode hole 42.
As shown in fig. 14. The radiofrequency ablation controller 2 comprises two radiofrequency electrode columns which can be respectively inserted into the two radiofrequency electrode holes, namely a radiofrequency positive electrode column and a radiofrequency negative electrode column. Two rf electrode columns are provided on the rf bus interface 26.
Preferably, the two radiofrequency electrode columns and the corresponding radiofrequency electrode holes have different cross sections, thereby preventing misinsertion, for example, one radiofrequency electrode column and the corresponding radiofrequency electrode hole have a square cross section, and the other radiofrequency electrode column and the corresponding radiofrequency electrode hole have a circular cross section. Preferably, the radio frequency electrode hole is provided with a spring, so that the radio frequency electrode column is more tightly electrically connected with the radio frequency electrode end in the radio frequency electrode hole during plugging, and the reliability of electrical connection is ensured.
When the radio frequency ablation is carried out, the radio frequency ablation control body 21 in the radio frequency ablation controller 2 is electrically connected with the radio frequency electrode columns in the two radio frequency electrode holes, and the on-off and the current during the radio frequency ablation are controlled through the radio frequency ablation control body 21.
Preferably, the proximal port 4 further comprises a medical fluid inlet 45, which is in sealing connection with the medical fluid tube 12 in the isolation layer 11. Preferably, the rf ablation controller 2 includes a medical fluid input 22 inserted into the corresponding medical fluid input port 45, so that the medical fluid can be injected into the distal rf ablation electrode 5.
Preferably, the proximal port 4 further comprises a cooling fluid input port 46 and a cooling fluid output port 47, which are respectively and correspondingly connected with the two fluid flow pipes in the isolation layer 11 in a sealing manner. The radiofrequency ablation controller 2 correspondingly comprises a cooling liquid input 23 and a cooling liquid output 24, which are respectively inserted into a corresponding cooling liquid input port 46 and a corresponding cooling liquid output port 47. Therefore, cooling liquid can be continuously injected from the radio frequency ablation controller 2 to the radio frequency ablation electrode 5 at the far end, and the high temperature generated by the radio frequency ablation electrode 5 in the ablation process is reduced.
As can be seen from fig. 13, the proximal interface 4 is stepped, and includes a first step interface 401 and a second step interface 402. The radio frequency positive electrode hole 41, the radio frequency negative electrode hole 42, the medical liquid inlet 45, the cooling liquid inlet 46 and the cooling liquid outlet 47 are all arranged on the first ladder interface 401, and the first ladder interface 401 is correspondingly matched and connected with the radio frequency main interface 26 of the radio frequency ablation controller 2. The second step interface 402 is used to connect with the chemical ablation injector 3.
Preferably, fig. 3 and 13 are combined. The proximal port 4 includes a chemical injection port 43, and the chemical injection port 43 is hermetically connected to a chemical conduit 81 of the hollow tube 8. The chemical ablation injector 3 correspondingly includes a chemical injector 31, which upon insertion into the chemical injection port 43 can thereby inject the chemical conduit 81 and thus the distal injector 6 with the chemotherapeutic drug.
The proximal port 4 further comprises a gas injection port 44, and the chemical ablation injector 3 further comprises a gas injection body 32, which is inserted into the gas injection port 44 to inject gas into the gas conduit 82 and thus the distal inflation body 62. The chemical general interface 33 of the chemical ablation injector 3 is correspondingly connected with the second step interface 402.
Therefore, the near-end interface is a public interface and can be respectively connected with the radio frequency ablation controller and the chemical ablation injector, the near-end interface is further connected with the corresponding input bodies through the corresponding interfaces, the near-end interface and the chemical ablation injector are isolated and independent from each other, the near-end interface and the chemical ablation injector cannot be mixed up and inserted wrongly, and the near-end interface has a special interface and is connected with the special input bodies, so that the special function is realized. For example, in the case of a chemical ablation injector, the proximal interface has only one chemical injection port connected to the proximal interface in a matching manner, and the chemical injection port is disposed at a different position from the aforementioned cooling liquid input port, cooling liquid output port, medical liquid input port, rf electrode port, and the like, so that they do not affect each other and can be used separately and independently. Therefore, the radiofrequency ablation controller and the chemical ablation injector are used in a time-sharing manner, and the radiofrequency ablation controller is usually connected to perform radiofrequency ablation, the connection between the radiofrequency ablation controller and the near-end interface is released after the radiofrequency ablation controller and the near-end interface are connected, and then the chemical ablation injector and the near-end interface are connected to perform chemical ablation.
Therefore, the invention discloses a radio frequency and chemical integrated ablation device, which comprises a transmission catheter, wherein a near-end interface for connecting a radio frequency ablation controller or/and a chemical ablation injector is arranged at the near end of the transmission catheter, a radio frequency ablation electrode for radio frequency ablation and an injection head for chemical ablation are arranged at the far end of the transmission catheter, an electric connector for connecting the radio frequency ablation controller and the radio frequency ablation electrode is arranged in the transmission catheter, a hollow pipe for connecting the chemical ablation injector and the injection head is further arranged in the transmission catheter, and the transmission catheter and the hollow pipe are integrated. Through the ablation device that this integration combines, can realize carrying out radio frequency ablation and chemical ablation simultaneously, also can carry out radio frequency ablation and chemical ablation by the timesharing, can also carry out treatments such as cooling, disinfection at the ablation in-process, be favorable to melting the improvement and the promotion of effect, can also reduce cost and treatment risk.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all equivalent structural changes made by using the contents of the present specification and the drawings, or applied directly or indirectly to other related technical fields, are included in the scope of the present invention.
Claims (10)
1. The radio frequency and chemical integrated ablation device is characterized by comprising a transmission catheter, wherein a near-end interface used for being connected with a radio frequency ablation controller or/and a chemical ablation injector is arranged at the near end of the transmission catheter, a radio frequency ablation electrode used for radio frequency ablation and an injection head used for chemical ablation are arranged at the far end of the transmission catheter, an electric connector used for connecting the radio frequency ablation controller and the radio frequency ablation electrode is arranged in the transmission catheter, a hollow pipe used for connecting the chemical ablation injector and the injection head is further arranged in the transmission catheter, and the transmission catheter and the hollow pipe are integrated.
2. The rf and chemical integrated ablation device according to claim 1, wherein the hollow tube is disposed outside the transmission conduit, the outer layer of the transmission conduit is a covering layer, the electrical connector is enclosed inside the covering layer, and the surface of the covering layer is further integrated with the surface of the outer layer of the hollow tube, thereby forming a double-pipe structure in which the outer surface of the transmission conduit and the outer surface of the hollow tube are integrated.
3. The rf-and-chemi-integrated ablation device of claim 2, wherein the proximal port comprises an rf ablation proximal port for connecting to the delivery catheter and a chemical ablation proximal port for hermetically connecting to the hollow tube.
4. The radiofrequency and chemical integration ablation device as claimed in claim 1, wherein the hollow tube is disposed inside the transmission conduit, the outer layer of the transmission conduit is a coating layer, the center of the hollow tube is sleeved inside the coating layer, an isolation layer is disposed between the coating layer and the hollow tube, and the electrical connector is disposed on the isolation layer, thereby forming an integrated structure in which the hollow tube and the electrical connector are sleeved inside the transmission conduit.
5. The radiofrequency and chemical integration ablation device as claimed in claim 4, wherein a medical fluid flow tube is further disposed in the isolation layer, the medical fluid flow tube extends to the radiofrequency ablation electrode, and the radiofrequency ablation electrode is provided with a diversion hole and is communicated with the medical fluid flow tube.
6. The radiofrequency and chemical integration ablation device as claimed in claim 4, wherein at least two cooling liquid flow pipes are further arranged in the isolation layer, the cooling liquid flow pipes extend to the radiofrequency ablation electrode, a cooling pipe network is arranged inside or on the inner side surface of the radiofrequency ablation electrode, two ends of the cooling pipe network are respectively connected with the two cooling liquid flow pipes, a cooling loop is formed by the two cooling liquid flow pipes and the cooling pipe network, and cooling liquid is injected into the cooling loop to cool the radiofrequency ablation electrode.
7. The radio frequency and chemical integrated ablation device according to claim 4, wherein the radio frequency ablation electrode is a hollow cylinder, one end of the radio frequency ablation electrode is hermetically combined with the transmission catheter, the other end of the radio frequency ablation electrode is of an arc-shaped structure, and an injection hole is formed in the arc center of the radio frequency ablation electrode; the injection head is arranged inside the radiofrequency ablation electrode, an expansion body is further arranged inside the injection head, and the expansion body can push the needle head of the injection head to be exposed out of the injection hole after being inflated.
8. The rf and chemical integration ablation device according to claim 5, wherein the proximal port comprises a medical fluid inlet port corresponding to a sealed connection with a medical fluid flow tube in the isolation layer, and the rf ablation controller comprises a medical fluid inlet body corresponding to a sealed connection with a medical fluid inlet port.
9. The rf and chemical integration ablation device according to claim 6, wherein the proximal interface comprises a cooling liquid input port and a cooling liquid output port respectively corresponding to and hermetically connected with the two liquid flow tubes in the isolation layer, and the rf ablation controller correspondingly comprises a cooling liquid input body and a cooling liquid output body respectively corresponding to and hermetically inserted and connected with the cooling liquid input port and the cooling liquid output port.
10. The rf and chemical integrated ablation device according to claim 7, wherein the proximal interface comprises a chemical injection port and a gas injection port, a chemical conduit and a gas conduit are disposed in the hollow tube, the chemical injection port is hermetically connected to the chemical conduit, the chemical ablation injector correspondingly comprises a chemical injection body, and a chemical therapeutic drug is injected into the chemical conduit after being inserted into the chemical injection port, so that the distal injection head injects a chemical therapeutic drug; the gas injection port is hermetically connected with a gas pipeline, the gas pipeline is also communicated with the expansion body, the chemical ablation injector correspondingly comprises a gas injection body, and the gas injection body is inserted into the gas injection port and then injects gas into the gas pipeline so as to inject gas into the expansion body at the far end.
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| CN202010686972.6A CN111772776A (en) | 2020-07-16 | 2020-07-16 | Radio frequency and chemical integrated ablation device |
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| CN202010686972.6A CN111772776A (en) | 2020-07-16 | 2020-07-16 | Radio frequency and chemical integrated ablation device |
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