CN111643631A

CN111643631A - A health-preserving medicinal preparation and its processing method

Info

Publication number: CN111643631A
Application number: CN202010718655.8A
Authority: CN
Inventors: 罗骥燊
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-07-23
Filing date: 2020-07-23
Publication date: 2020-09-11

Abstract

The invention belongs to the field of medicines, and particularly relates to a health-preserving pharmaceutical preparation which comprises the following components in parts by weight: 15-30 parts of ginseng, 20-50 parts of lily, 10-40 parts of fructus amomi and 15-30 parts of liquorice. The invention also relates to a processing method of the health-preserving medicinal preparation, which comprises the following steps: (1) respectively pulverizing Ginseng radix and fructus Amomi, and sieving with 400 mesh sieve to obtain Ginseng radix powder and fructus Amomi powder; (2) decocting Bulbus Lilii and Glycyrrhrizae radix in water to obtain decoction; (3) concentrating the medicinal juice obtained in the step (2) into an extract, adding the ginseng powder and the fructus amomi powder obtained in the step (1), uniformly mixing, and drying at low temperature to obtain the granular medicine, namely the health-preserving medicinal preparation. The health-preserving medicinal preparation obtained by the scheme is suitable for long-term dietary therapy conditioning of people with tumor postoperative radiotherapy and chemotherapy, diabetes type II, chronic cough and asthma, long-term stay-up sub-health syndrome, chronic gastritis, gastric ulcer, alcoholism and alcoholic liver.

Description

A health-preserving medicinal preparation and its processing method

Technical Field

The invention belongs to the field of medicines, and particularly relates to a health preserving pharmaceutical preparation and a processing method thereof.

Background

The aging degree of the national social population is getting more and more serious, and various chronic diseases are gradually increased under the influence of a plurality of factors such as diet, unhealthy life style, high-tension mental stress, long-term heavy physical energy overdraft, environmental pollution and the like. Therefore, some health preserving medicines or health products are gradually receiving attention. The existing health-care products in the market comprise: brain platinum for improving human sleep and regulating intestinal function; dongpeng special drink and red cattle for supplementing energy and resisting fatigue of human body; wanglaoji, Jiaduobao and Zhengzheng for clearing heat and purging fire; pine pollen capsule for improving immunity.

However, the health-care products are only suitable for daily eating by people and do not have specific curative effects on certain diseases, so that research and development of an innovative health-care product which is both disease-free and disease-treated is needed.

The technology is a six-generation health-preserving empirical prescription of traditional Chinese medicine based on the theory of 'simultaneous treatment of different diseases' of traditional Chinese medicine, and the essential reasons of the human body harmony diseases are that vital qi is insufficient, pathogenic qi can dry, and spleen and lung functions are weak, so that qi and blood disorder is caused, the congenital exhaustion of kidney-yin and kidney-yang cannot be timely supplemented, and heart and liver are affected, and even five viscera are damaged. Only natural ecological medicine-food homologous materials integrating the spiritual activities of heaven and earth and the lusterless days and months are adopted to fundamentally supplement yin-yang imbalance of the organism, promote the organism to return to the five internal organs to generate mutually and achieve the state of balancing qi, blood and yin and yang.

The health product of the technology has effective body conditioning effect on people who suffer from tumor postoperative radiotherapy and chemotherapy, diabetes type II, chronic cough and asthma, long-term stay up sub-health syndrome (drowsiness and hypodynamia, dry mouth, aphtha, inappetence, facial acne, color spots, dry skin and pruritus, female menstrual disorder, male alopecia, sexual hypofunction and the like), chronic gastritis, gastric ulcer, alcoholism and alcoholic liver, relieves health injury caused by chronic diseases, improves the happy life quality of people, and realizes healthy Chinese targets.

Disclosure of Invention

The invention aims to provide a health-preserving pharmaceutical preparation which has accurate indication by syndrome differentiation, simple and reasonable formula, clinical application for more than one hundred years and effective prescription proved by full and deep research of modern pharmacology, and has the functions of supplementing qi, nourishing yin, promoting the production of body fluid, strengthening spleen and resolving dampness.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows: a health preserving pharmaceutical preparation is composed of the following components in parts by weight: 15-30 parts of ginseng, 20-50 parts of lily, 10-40 parts of fructus amomi and 15-30 parts of liquorice.

By adopting the technical scheme of the invention, ginseng has the effects of tonifying qi, promoting the production of body fluid, quenching thirst, tonifying spleen and lung, controlling the deficiency of qi of the five internal organs, tonifying the conservative spirit of the six internal organs, producing blood with sweet and warm properties to tonify the ginseng, promoting the growth of yin and blood, strengthening the body resistance and tonifying qi and blood; the lily is sweet in taste and slightly cold, can clear heat in upper jiao, enters heart and lung to moisten lung and relieve cough, clears heart and soothes nerves and is mutually reinforced with ginseng as the ministerial drugs; fructus amomi is pungent in flavor and warm in property, enters the channels of the spleen and the stomach, and the spleen, the lung and the kidney are grown mutually, so that the fructus amomi is capable of tonifying the lung and the kidney, regulating primordial qi, activating qi, regulating the middle warmer, resolving dampness of alcohol food, activating the spleen, nourishing the stomach and assisting the acquired health and transportation of all things; the liquorice is sweet in taste and neutral in nature, and is used for removing cold and heat pathogenic qi of internal organs of the heart, the spleen and the stomach, relieving healthy qi, nourishing yin and blood, strengthening bones and muscles, tonifying spleen and stomach and growing muscles, moistening lung and strengthening strength, treating sore pain of incised wound and harmonizing and detoxifying. The Chinese medicinal composition has the effects of invigorating qi and blood and balancing yin and yang. The acquired resources can nourish the congenital roots, and the effects of losing weight and prolonging life are achieved for a long time. The health tea is suitable for patients with radiotherapy and chemotherapy period after tumor operation, diabetes type II, chronic cough and asthma, long-term sub-health syndrome, chronic gastritis, gastric ulcer, alcoholism and alcoholic liver. It is indicated for chronic deficiency of both qi and yin, qi deficiency and blood stasis, deficiency of both spleen and lung, deficiency of both heart and spleen, and disharmony between spleen and stomach.

The invention also aims to provide a processing method of the health-preserving medicinal preparation.

In order to achieve the purpose, the invention adopts the technical scheme that: a processing method of the health-preserving medicinal preparation comprises the following steps:

(1) respectively pulverizing Ginseng radix and fructus Amomi, and sieving with 400 mesh sieve to obtain Ginseng radix powder and fructus Amomi powder;

(2) decocting Bulbus Lilii and Glycyrrhrizae radix in water to obtain decoction;

(3) concentrating the medicinal juice obtained in the step (2) into an extract, adding the ginseng powder and the fructus amomi powder obtained in the step (1), uniformly mixing, and drying at low temperature to obtain the granular medicine, namely the health-preserving medicinal preparation.

According to the scheme, the ginseng and the fructus amomi are pulverized and sieved to obtain the medicinal powder, compared with the traditional decocting mode, the effective ingredients in the medicine are reserved to the maximum extent, the loss of precious and fine medicinal materials is reduced, and the resources and the cost are saved; the effective components can be fully dissolved out by decocting the lily and the liquorice; the obtained health promotion medicinal preparation is suitable for long-term diet therapy conditioning of tumor postoperative radiotherapy and chemotherapy period, diabetes type II, chronic cough and asthma, long-term stay up sub-health syndrome, chronic gastritis, gastric ulcer, alcoholism and alcoholic liver.

Specifically, in the step (1), before the ginseng and the fructus amomi are crushed, washing and drying are carried out. After being washed and dried, the ginseng and the villous amomum fruit are respectively subjected to superfine grinding and sieving treatment, thereby being beneficial to keeping natural active ingredients and volatile oil ingredients without being damaged and lost, improving the human bioavailability of the active ingredients of the medicine, reducing the loss of precious and fine medicinal materials, saving resources and cost and improving the health-care food effect.

In the step (2), before the decoction in water, the lily and the liquorice are soaked in water for 2-4 hours, and the water adding amount is 4-6 times of the total mass of the lily and the liquorice. In the process of soaking the medicinal materials, water can be fully absorbed into the medicinal materials, so that the first time can shorten the decoction time, and the second time can ensure that water-soluble components in the medicinal materials can be fully dissolved out during decoction.

The earthen jar is used as a decocting container, water is not required to be added in the decocting process, and the medicinal materials are soaked and the water is added for decocting. In the decocting process, the decoction is decocted for 1-1.5 hours by slow fire, the decoction is stopped when the amount of the decoction is 10-20% of the amount of the added water for decoction, and the decoction is separated. The earthen jar fired by the traditional method for decocting the medicines can ensure that the medicines are heated uniformly during decoction, the decoction effect is better, and the effective components can be protected to the maximum extent. Decocting the decoction with slow fire: firstly, the rapid reduction of the solution amount caused by overhigh temperature and large water evaporation amount in the decoction process is prevented, and the dissolution rate of effective components in the medicine (volume quality) is reduced; secondly, the loss of volatile components in the medicine is less when the medicine is decocted by slow fire than when the medicine is decocted by high temperature, so that the effective components of the medicine can be retained to the maximum extent.

Wherein the decoction is water obtained by soaking. In the soaking process, when the medicine absorbs water, some soluble components in the medicine can be dissolved out, in order to avoid the loss of the effective components of the medicine, the soaking process can be directly carried out in a decocting container, the medicine is directly heated and decocted after being soaked, and the waste of the effective components caused by the repeated transfer of the medicine and the medicine juice is also avoided.

The decocting process is carried out twice, after the first decocting is finished and the decoction is separated out, 4-6 times of water by mass is added into the medicine residues, the decocting process is repeated, and the decoction separated out for the second decocting is mixed with the decoction obtained by the first decocting. Therefore, the effective components in the medicine can be fully dissolved out, meanwhile, the effective components of the rhizome type traditional Chinese medicinal materials can be fully dissolved out, the active components of the medicine can be protected to the maximum extent, and the content of the effective components of the medicine juice can be improved.

Mixing the decoction, boiling with strong fire, concentrating to obtain extract, adding superfine Ginseng radix powder and fructus Amomi powder, mixing, and vacuum drying at 50 deg.C to prevent destruction of effective bioactive components and loss of volatile effective components, which affect dietetic therapy effect. Finally, preparing the granular preparation, namely the health-preserving medicinal preparation product.

In the process of processing and preparing the health-preserving medicinal preparation, the solid preparation is obtained without adding excipients and flavoring agents. In order to adapt to the fast-paced life of modern people, the medicine juice is concentrated and mixed with superfine powder to obtain a solid preparation, and the solid preparation is easy to store and carry for a long time. The medicine juice is extracted and refined by a conventional water extraction and alcohol precipitation method or an alcohol extraction and water precipitation method in the field to obtain the effective active ingredients of the health-care medicine for supplementing qi, nourishing yin, promoting the production of body fluid, strengthening spleen and resolving dampness. The active ingredients can also be combined with pharmaceutically acceptable carriers or excipients and flavoring agents into various pharmaceutical dosage forms, such as oral liquid, paste, granules, etc.

Detailed Description

The technical solution of the present invention is further described below with reference to examples.

First, pharmacological research

(one) Ginseng radix

1 traditional medicine property

1.1 the properties, flavor and meridian tropism

Sweet, slightly bitter and warm in nature. It enters spleen and lung meridians.

1.2 functional mechanism:

1.2.1 invigorating spleen and benefiting lung

The related works are common in all generations. The treatise on the herb properties: ginseng is used for treating deficiency of five internal organs, fatigue, impairment of deficiency, emaciation, regurgitation, emesis, abdominal distention, and mental retention. Title of "medical enlightenment source": ginseng, radix Ginseng, for the treatment of insufficiency of spleen-stomach yang-qi, shortness of breath, scanty qi, and tonifying middle-jiao and slow-jiao … …, is called Ben Cao Jing Shu (herbal Jing Shu): "true qi is deficient in the interior, so it is cold in the stomach and intestines, but not cold in the case of vigorous qi returning to yang , … … regulates middle energizer, and spleen tonifies it, it regulates middle energizer automatically ".

1.2.2 promoting the production of body fluid to quench thirst

Zhang element in the "Yi Xue Yuan" (self-source of medicine) and "Zhen Zhu Sac" (Pearl bag) both the characters of ginseng for quenching thirst and promoting the production of body fluid are recorded. The "Ben Cao Jing Shu" (Ben Cao Jing Shu) discusses the mechanism of action of Ginseng in this respect from the relationship between qi and yin and fluid: for diabetes, the qi returning will produce body fluid, and the body fluid will self-stop thirst .

1.2.3 benefiting qi, nourishing blood, promoting blood circulation

The book materia medica Zheng (materia medica treatment) says: for ginseng, both qi deficiency and blood deficiency can tonify … … collapse of yin and blood, and this failure is … … after the burst has occurred, which is sweet and pure in taste, so it can tonify blood. Li Dongyuan in the theory of spleen and stomach, discussed the mechanism of blood generation of Ginseng based on the theory of generation of qi and blood: it is sweet and warm, and can produce blood, but not blood. B, marking: the middle energizer is the method of tonifying blood with the ginseng, and yang hyperactivity can generate yin and blood, while the middle energizer is the method of tonifying blood with the ginseng, and the blood cannot be generated by itself, so yang qi generation is required to generate the yang qi, yang growth is the method of yin growth, and blood is vigorous . The famous physicians' book clearly records the characters of ginseng for promoting blood circulation, breaking hard mass and keeping people forget.

1.2.4 about the actions of Ginseng radix in removing heat due to its sweet and warm nature, discussion of Lidongyuan is first: ginseng, radix astragali and radix Glycyrrhizae are sweet and warm in nature, and are herbs for relieving high fever, purging yin fire, tonifying primordial qi and also for treating sore house holy.

2 modern pharmacological research

2.1 Effect on the Central nervous System

2.1.1 the regulating action on the excitation and inhibition of the central nervous system can not only improve the excitation process of the brain, but also improve the inhibition process, so that the inhibition tends to concentrate, the differentiation is more complete, and the excitation and inhibition processes are restored to balance.

2.1.2 enhancing the learning and memory function, the ginseng promotes the synthesis and release of acetylcholine in the central nervous system, increases the content of DA and NA in the brain, promotes the synthesis of RNA and protein in the brain, and improves the blood supply and oxygen supply of the brain, which is the pharmacological basis of ginseng intelligence development.

2.2 anti-ageing action

2.2.1 Life-prolonging action

The ginseng flower is used for breeding bees, so that the service life of the bees is obviously prolonged by 10-15 days. The ginseng injection of 15-16 mug/ml can obviously promote the in vitro culture of human embryo lung diploid SL₇The growth and proliferation capacity of the strain fibroblast and the service life of the cell can be prolonged; CLMR (clMR) for human embryo diploid fiber cell_-90、WI_-38The life of the cells in the test tube is obviously prolonged by carrying out subculture.

2.2.2 effects on anti-peroxidation of cells and scavenging free radicals

The maltitol contained in Ginseng radix can combine with free radicals in vivo, inhibit lipid peroxidation of ethanol in mouse liver, and reduce accumulation of age-increasing pigment and lipofuscin. Therefore, the cell peroxidation resisting and free radical scavenging effects of the ginseng are part of the anti-aging effects of the ginseng.

2.3 enhancing the adaptability of the body

2.3.1 Regulation of the entire organism

Ginsenoside can obviously improve CAMP level of yang deficiency animals, reduce CGMP level, and increase CAMP/CGMP ratio. The ginsenoside also has regulating effect on the integration function of endocrine system, which indicates that the ginseng has obvious regulating effect on the adaptability of organism.

2.3.2 anti-stress Effect

Can obviously improve⁶⁰Tolerance of CO-irradiated miceAnd has obvious protection effect on damage of adrenal gland function and immune function caused by long-term microwave irradiation of mice.

2.3.3 anti-fatigue Effect

Ginsenoside can increase the ability of brain cells in lower part of rat to bind cortisol by several times to several hundred times. The combination of brain cells and cortisol can improve the selection ability and discrimination ability of the body; the brain cells combine with ACTH to enhance the motor function and the arousal response of the brain, both of which can make the body generate temporary activity and comfort, thereby playing the role of anti-fatigue.

2.3.4 anti-mutational Effect

The ginseng polysaccharide has obvious inhibition effect on the increase of mouse bone marrow hyperphagia erythrocyte microsome due to chromosome aberration rate caused by X-ray irradiation and sister chromosome exchange caused by cyclophosphamide, the panaxadiol saponin can obviously reduce the aberration rate of male rat germ cell sperms, and the anti-mutation effect of ginseng is also one of mechanisms of prolonging the life of organisms.

2.4 Effect on immune function

2.4.1 enhancing phagocytic function of reticuloendothelial system, and restoring the inhibition of cyclophosphamide-induced leucopenia, macrophage phagocytic function, hemolysin formation and delayed allergy to normal level.

2.4.2 enhancing the immune function of cells, the ginsenoside Rd has obvious antagonism on spleen and thymus atrophy, T lymphocyte reduction and lymphocyte softening function reduction caused by prednisolone acetate. The panaxan and ginsenoside have certain protective effect on immunity damage caused by radioactive rays.

2.4.3 promoting the formation of specific antibody, ginseng has obvious enhancement effect on the generation of antigen-stimulated animal antibody, and ginseng and its extract ginsenoside are not only immunopotentiators, but also immunomodulators.

2.5 Effect on endocrine

2.5.1 Effect on protein and nucleic acid metabolism

Ginseng radix has effect in promoting synthesis of brain protein RNA and DNA, and ginsenoside Rg₁Can not be atThe low concentration or the high concentration can increase the protein content in the brain of the mouse.

2.5.2 Effect on sugar metabolism

The panaxan A, B, C, D, E, U, T, S, O separated from Ginseng radix is effective in lowering blood sugar, wherein panaxan U has strongest effect. The acidic polypeptide composed of adenosine and 14 amino acids in ginseng root can resist the action of adrenalin, ACTH and glucagon, enhance the effect of insulin on sugar metabolism and inhibit the action of insulin for converting glucose into fat.

2.5.3 hypolipidemic Effect

The blood fat reducing function of ginseng is related to that ginseng can promote lipid metabolism and influence synthesis, decomposition, transformation and excretion of cholesterol and lipoprotein in blood.

2.6 antitumor Effect

2.6.1 cancer suppressing action

The ginseng contains various saponins, polysaccharides and volatile oil, which have anti-tumor effect. Ginsenoside for treating mouse sarcoma S of Morris hepatoma generation 25 mouse₁₈₀ginsenoside-Rh₂For promyelocytic leukemia HL-60 tumor strain, Morris tumor strain, mouse spontaneous melanoma, cervical cancer Hela cell, ginseng stem and leaf total saponin gastric tumor cell, and sarcoma S₁₈₀Etc. all have different degrees of inhibitory effect. After long-term administration of Ginseng radix Rubri (processed product of Ginseng radix) extract, it has different degrees of inhibiting effect on carcinogenesis of chemical substances such as urethane, N-methyl-N-nitroso-N-nitro-arc, and aflatoxin, so that carcinogenesis rate of above substances is reduced significantly, and growth of above substances can be inhibited.

2.6.2 synergistic synergism on antitumor Agents

Ginseng radix has antitumor, anticancer effects, and is also synergist of antitumor drug, and Ginseng radix extract can enhance Fe-gabur anticancer effect, and Fe-gabur can be used together with Ginseng radix extract to significantly improve survival rate of mouse, and is used for S of mouse₁₈₀The growth of sarcoma is also inhibited. Ginseng radix and cyclophosphamide are used together to produce obvious antitumor synergistic effect.

2.6.3 relieving side effects of anticancer drugs

The ginsenoside preparation has effect in relieving toxicity of anticancer drugs. The cephalotaxone, homoharringtonine and adriamycin are anticancer drugs with bone marrow and heart inhibiting effect. The compound preparation containing ginsenoside, oleanolic acid, anisole, small cephalotaxine and homoharringtonine has obvious treatment effect on leukemia and obviously weakens the toxic reaction of cephalotaxine on heart and hematopoietic organs. After the ginseng preparation is taken by a patient with tumor, the damage symptom of the chemotherapy drug to the organism can be obviously relieved, the bone marrow inhibition can be relieved, and the symptom can be relieved.

2.7 hypoglycemic action

Ginseng radix polypeptide, polysaccharide and saponin all have effects of lowering blood sugar. The ginseng polypeptide has the functions of reducing blood sugar, promoting glycogen decomposition, inhibiting synthesis of glycogen by lactic acid, activating activity of succinic acid dehydroacid (SDH) and CCH, and enhancing aerobic oxidation of sugar. The hypoglycemic effect of ginseng polysaccharide may be related to its activity in inhibiting lactic acid dehydrogen acid, succinic acid dehydrogen acid and cytochrome oxydic acid.

2.8 Effect on digestive System

2.8.1 enhancing the detoxifying power of the liver

The ginseng can shorten the anesthesia time of the ethanol to rabbits and dogs, so that the ethanol content in the blood of the rabbits is quickly reduced. The ginsenoside can resist the inhibiting effect of malonate on dehydrosuccinic acid, and the ginsenoside has effects of resisting and relieving liver injury, vascular wall connective tissue hyperplasia and increased transhistidine caused by carbon tetrachloride, and has effect of enhancing liver detoxification function. The action of the ginseng is related to that the ginseng can enhance the activity of alcohol dehydrogenase, succinate dehydrogenase, glutathione transferase, malate dehydrogenase and RNA polymerase in liver and enhance the oxidative phosphorylation process in liver cell microsome.

2.8.2 protective action against gastric mucosal Damage

The panaxaline polysaccharide component GRA-2 has inhibitory effect on gastric mucosa injury caused by hydrochloric acid or ethanol, with inhibition rates of 57.3% and 74.1%, respectively, and has certain protection effect on gastric mucosa.

(II) Glycyrrhiza uralensis

1 traditional medicine property

1.1 the properties, flavor and meridian tropism

Sweet in flavor and neutral in nature. It enters heart, spleen and stomach meridians.

1.2 mechanism of function

Li Shizhen reviewed the pharmacological discussion of the properties of Licorice root in Ben Cao gang mu by physicians of all generations, he summarized Licorice root indications: the five zang-organs and six fu-organs have the effects of strengthening muscles and bones, growing muscle, strengthening strength, treating carbuncle, removing toxic materials, reducing weight and prolonging life after long-term use. "Ben Cao Jing" (the book of materia Medica) … … unprocessed for purging fire and heat, cooked for dispelling exterior cold, relieving pharyngalgia, removing pathogenic heat, relieving healthy qi, nourishing yin and blood, invigorating spleen and stomach, and moistening lung ".

2 modern pharmacological research

2.1 Effect on digestive System

2.1.1 anti-gastric ulcer Effect

Glycyrrhizin and glycyrrhetinic acid derivative gastrinone (18-beta-glycyrrhetinic acid hemisuccinate disodium salt) have certain gastric ulcer resisting effect.

2.1.2 spasmolytic action

TM₁₀₀The flavone compounds such as isoliquiritigenin can also relieve BaCI₂And intestinal spasm caused by histamine and isoliquiritigenin also have strong spasmolytic effect on intestinal smooth muscle.

2.1.3 hepatoprotective effects

Oral administration of glycyrrhizic extract and licoflavone to carbon tetrachloride (CCI)₄) The induced liver injury of the rat has obvious protective effect, can obviously reduce the degree of degeneration and necrosis of liver tissues, and recovers the regeneration and synthesis functions of glycogen and ribonucleic acid in liver cells. The activities of serum glutamic acid alanine and lactic acid dehydrogen acid are obviously reduced, and the licorice flavonoids have protective effect on the liver injury of mice caused by ethanol, and obviously inhibit the increase of the content of malondialdehyde in liver tissues and the exhaustion of reductive glutathione. It is also thought that glycyrrhetinic acid has liver protecting effect and can antagonize cell lipid peroxidation and inhibit Ca²⁺And the flow into the cells.

2.2 Effect on immune System function

2.2.1 enhancement of nonspecific immune function

The glycyrrhizin is 25mg/kg, and can be administered by abdominal cavity, so as to obviously improve clearance index of mice to intravenous injection carbon granules, and can stimulate phagocytosis of macrophages at low concentration. Glycyrrhiza polysaccharide, glycyrrhizin UA, UB, UC also have obvious activating effect on reticuloendothelial system.

2.2.2 enhancement of specific immune function

Glycyrrhizic acid at a certain concentration can promote the production of polyclonal antibodies, and the increase of antibody production is related to the increase of IL-1 production. Glycyrrhizin also increases the levels of gamma interferon (γ -IFN) production by spleen cells induced by ComA. 100mg/kg of glycine oxalate can also be administered for 7 days to make mouse spleen Prostaglandin (PGE)₂) And a significant increase in the amount of CAMF. Rat lymphocytes can also obviously increase the secretion of PGE under the action of glycyrrhizin. The liquorice and the extract thereof have certain regulation effect on the body immunologic function.

2.2.3 antiallergic action

Glycyrrhizin can obviously inhibit passive skin allergic reaction of mice, antagonize histamine, L_XAnd slow-reacting substance contraction of isolated ileum rabbit and isolated tracheal smooth muscle of guinea pig. The antiallergic effect of liquorice is one of the main manifestations of corticoid-like effect. The effect and the ability to inhibit phosphatidic acid A₂Activity, thereby inhibiting PGE₂The CAMP concentration is increased, and the release of active substances such as histamine is prevented; reduction of tissue cell pair PGE₂Reactivity of active factors such as MIF (macrophage migration inhibitory factor) and the like, and inhibition of antibody production.

2.3 Effect on the Central nervous System

Glycyrrhetinic acid (125mg/kg) and paeoniflorin can induce sedative effect and hypnotic effect on mice. FM₁₀₀Has tranquilizing effect and also has effect in inhibiting convulsion caused by pentylenetetrazol. Glycyrrhetinic acid and glycyrrhizin have antipyretic effects of different degrees on heat-producing rat, mouse and rabbit.

2.4 Effect on the cardiovascular System

2.4.1 Effect on the Heart

The decoction of radix Glycyrrhizae can increase the amplitude of systole of Bufo siccus in vitro. The glycyrrhizin can excite the isolated heart of the toad and has obvious synergistic effect with epinephrine; it also has effect in resisting the inhibition of acetylcholine (Ach) and physostigmine on heart.

2.4.2 antiarrhythmic action

The radix Glycyrrhizae Preparata extract crude drug 1g/kg is administered intravenously, and has inhibitory effect on aconitine-induced ectopic rhythm and supraventricular arrhythmia, and the glycyrrhetinic acid 18- β has different degrees of inhibitory effects on chloroform-induced ventricular fibrillation of mouse and chloroform-induced supraventricular arrhythmia of rabbit, and can also make CaCI₂The time to the onset of induced supraventricular arrhythmias is significantly prolonged in rats.

2.4.3 hypolipidemic Effect

The blood lipid reducing effect of glycyrrhizin is related to administration dosage, and at the dosage of 2mg/kg, the blood plasma cholesterol content of the rabbit with ventricular atherosclerosis can be reduced, and the development of the arteriosclerosis of the aorta and the coronary artery can be prevented. When the dosage is 10mg/kg, the contents of cholesterol and triglyceride in the blood plasma of the experimental hyperlipoidemia rabbits can be obviously reduced. The dose was 40mg/kg, but not effective.

2.4.4 antiplatelet aggregation Effect

3-aromatic coumarin derivative GU-7 separated from Glycyrrhrizae radix has obvious effect in inhibiting platelet aggregation.

2.5 Effect on the respiratory System

2.5.1 antitussive effect

Licoflavone, Glycyrrhrizae radix extract and glycyrrhetinic acid all have obvious inhibiting effect on mouse cough caused by ammonia water and sulfur dioxide. Glycyrrhetinic acid with strongest effect and cholate contained in Glycyrrhrizae radix are injected subcutaneously at a dose of 1mg/kg, and have a cough suppression rate of 80%, and the antitussive effect is different from hydrocortisone and is generated through central nerve.

2.5.2 phlegm eliminating action

Licoflavone, Glycyrrhrizae radix extract and glycyrrhetinic acid not only have antitussive effect, but also have good expectorant effect, and Glycyrrhrizae radix can promote secretion of throat and bronchus, so that phlegm can be easily expectorated.

2.5.3 antiasthmatic action

Intraperitoneal injection of licorice decoction or licorice extract Lx₆₆The reduction of β -receptor reactivity and the reduction of β -receptor number caused by repeated application of isoproterenol can be prevented, which indicates that the liquorice has certain effect of relieving asthma.

2.6 detoxification action

2.6.1 detoxification of chemical substances

The glycyrrhiza extract and glycyrrhizin have obvious detoxification effect on the toxicity of substances such as strychnine, urethane, cocaine, arsenic phenoxide, ascending pump and the like. The liquorice decoction has the second detoxifying effect on the toxin of the printed defense, the caffeine, the acetylcholine, the pilocarpine, the nicotine and the barbital, and can effectively weaken the toxicity of the dichlorvos, so that the toxic and death percentage of mice is obviously reduced.

2.6.2 detoxification and potentiation

The glycyrrhizin, the anticancer drugs camptothecin and the agricillin have the functions of detoxification and synergism, and the glycyrrhizic acid monoammonium salt can obviously resist the toxicity of the camptothecin and enhance the antitumor effect. Is related to that licorice has corticoid-like action and improves the tolerance of the organism to toxicants, and also can obviously improve the liver cytochrome P_-450The content of (b) is related to the induction of detoxification of liver enzymes.

2.7 anti-inflammatory action

The anti-inflammatory effect of licorice is related to the effect of licorice on the biological oxidation process of cell and the reduction of sensitivity of cell to inflammatory reaction substance. The flavone component in Glycyrrhrizae radix can obviously inhibit the generation of 5-HETE, 12-diheTE, 12-HETE, etc. of arachidonic acid metabolite of leukocyte and platelet, inhibit the release of lysosome enzyme from leukocyte, increase CAMP concentration to prevent the release of histamine, etc., and inhibit the association of degranulation reaction.

2.8 antibacterial and antiviral action

2.8.1 antibacterial action

The licorice extract and sodium glycyrrhetate can inhibit staphylococcus aureus, tubercle bacillus, colibacillus, amoeba protozoon and trichomonad in vitro, 18- β sodium glycyrrhetate can inhibit staphylococcus aureus and bacillus subtilis G⁺Has obvious inhibition effect with bacillus.

2.8.2 antiviral action

Glycyrrhizin can inhibit the proliferation of more than 98% of AIDS virus at a concentration of 0.5 mg/ml; the glycyrrhiza polysaccharide has inhibitory effect on vesicular stomatitis virus, adenovirus type III, herpes simplex virus type I, vaccinia virus, etc., and can significantly inhibit the incidence of cytopathic effect, so that the cells cultured by the tissue are maintained.

2.9 other effects

2.9.1 Oxidation resistance

Licoflavone (FG) can obviously inhibit the increase of malondialdehyde in liver homogenate of mice when the dosage is 2.5-25 μ g/ml, and has obvious scavenging effect on alkaline dimethyl sulfoxide, oxygen free radicals generated by xanthine oxidase and oxygen free radicals and hydroxyl free radicals released by polyamine cells stimulated by PMA when the dosage is 0.265-26.5 μ g/ml or 2.58-258 μ g/ml.

2.9.2 antidiuretic action

Glycyrrhizin can significantly reduce urine volume in rats accompanied by Na⁺Decrease in discharge amount of (K)⁺The discharge amount of (2) is also reduced. After the adrenal gland of the rat is cut off, the glycyrrhizin can still enable Na⁺、K⁺The discharge amount is reduced. Glycyrrhetinic acid and its salt also have remarkable diuretic effect.

2.9.3 Effect on Estrogen

Glycyrrhizin and glycyrrhetinic acid can inhibit the growth of estrogen on uterus of immature animals, and the same effect can be obtained after adrenal gland and ovary are removed.

2.9.4 antitumor effect

Glycyrrhizin has obvious inhibition effect on rat precancerous lesion caused by diethylnitrosamine.

(III) Amomum fruit

1 traditional medicine property

1.1 the properties, flavor and meridian tropism

Pungent taste and warm nature. It enters spleen and stomach meridians.

1.2 mechanism of function

1.2.1 moving qi and regulating the middle warmer, stimulating appetite and promoting digestion.

The herbal books from Tang Dynasty all record the property of Sha ren to promote flow of qi, regulate the middle warmer, stimulate the appetite and promote digestion. For example, in materia Medica of drug property: "Xiaohua Gu and Zhi Cold-wind abdominal pain". Compendium of materia Medica: the traditional Chinese medicine has the effects of warming spleen and stomach, ascending qi and cough, playing the flavor of wine, regulating the middle warmer and promoting qi circulation and treating qi stagnation of spleen and stomach. Tonifying lung and spleen, nourishing stomach and kidney, regulating primordial qi, dredging qi, dispelling cold, relieving distension and fullness, and relieving dysphagia and emesis … … ".

1.2.2 warming spleen to stop diarrhea

Many books record the spleen-warming and diarrhea-checking functions of Sha ren, as in Kai Bao Ben Cao (materia Medica of Kai): it is indicated for dysentery with red and white discharge, abdominal pain due to deficiency. The herbal Zhenzhen: it is effective in treating dysentery with red and white color when entering large intestine. In a word, Sha ren is pungent in flavor, warm in property, resolve dampness, activate spleen and invigorate stomach, so it is mainly indicated for spleen, and it is indicated for deficiency-cold of spleen and stomach.

2 modern pharmacological research

2.1 Effect on the nervous System

Through intragastric administration, the disappearance and recovery of the righting reflex are regarded as the sleep time, and the fructus amomi is found to be capable of obviously shortening the sleep time of mice induced by the pentobarbital sodium. The amomum fruit and the indomethacin have obvious synergistic effect on the inhibition of the mouse central nervous system caused by the sodium pentobarbital.

2.2 Effect on digestive System

The fructus amomi has the effect of resisting stress ulcer of a mouse, can obviously increase gastric acid secretion activity and pepsin activity of the rat, and the fructus amomi leaf oil can prevent the formation of pyloric ligation ulcer of the rat, but the anti-ulcer effect of the fructus amomi leaf oil has no obvious relation with gastric acid secretion. The amomum fruit leaf oil also has obvious inhibiting effect on the movement of isolated ileum of rabbits and guinea pigs, has obvious relaxing effect on spastic contraction caused by barium chloride, acetylcholine and histamine phosphate, can completely block the isolated intestinal spasm of rabbits caused by barium chloride, and partially blocks the isolated intestinal spasm of rabbits caused by acetylcholine and histamine phosphate. After the fructus amomi is irrigated to a mouse for 40min, compared with a control group, the moving distance of the activated carbon in the gastrointestinal tract is obviously different, and the fructus amomi is proved to have the function of promoting gastrointestinal peristalsis.

2.3 Effect on platelet aggregation function

The fructus amomi suspension has obvious inhibiting effect on ADP-induced rabbit platelet aggregation, and the action time is prolonged along with the increase of the dosage. The fructus amomi suspension has obvious protective effect on the acute death of mice induced by arachidonic acid or a mixture of collagen and adrenaline.

2.4 Effect on the immune System

When PFC is measured by a polystyrene plate method, the fructus amomi has the effect of obviously inhibiting mouse antibody from forming cells.

2.5 Effect on the liver

The fructus Amomi water extract can increase liver coefficient of mouse, and homogenize liver cell factor P₄₅₀The content has no obvious influence.

(IV) Lily bulb

1 traditional medicine property

1.1 the properties, flavor and meridian tropism

Sweet and slightly cold. It enters heart and lung meridians.

1.2 mechanism of function

1.2.1 moistening lung to arrest cough, it is used for cough due to lung heat, cough due to overstrain, hemoptysis, chronic cough due to lung heat with bloody sputum, and combined with coltsfoot flower.

1.2.2 it has effects of clearing away heart-fire and tranquilizing mind, and can be used for treating absentmindedness, language, action, diet, sensory disturbance, bitter taste, and dark urine.

1.2.3 for lung pain, the lily bulb is singly used and cooked or steamed.

1.2.4 it is used for treating atrophic gastritis, and is prepared from Bulbus Lilii, radix Paeoniae alba, radix astragali, and radix Glycyrrhizae.

1.2.5 can be used for treating neurasthenia or climacteric syndrome, and is cooked with Bulbus Lilii and semen Ziziphi Spinosae.

[ Ezeria ] lily is sweet and moist, can tonify, moisten lung to arrest cough, clear heart fire and tranquilize mind. It is sweet in flavor and tonifying, cold in property and clearing heat, entering heart and lung meridians, so it has the actions of moistening lung to stop cough, clearing heart fire and tranquilizing. The product can be used as both medicine and food, has bitter and cold properties, and can be used for treating lung dryness, dry cough, cough with excessive consumption, hematemesis, and late stage of fever, vexation, palpitation, insomnia, dreaminess, and listlessness, and has effects of health promotion and life prolonging.

2 modern pharmacological research

2.1, components: bulbus Lilii contains hydrolyzed colchicine, starch, protein, fat, sugar, calcium, phosphorus, and iron.

2.2 pharmacological study: the decoction has effects in relieving mouse cough caused by ammonia water, relieving toad asthma caused by tissue ammonia, preventing leukopenia caused by cyclophosphamide, and inducing estrogen-like action.

Second, processing of health preserving medicinal preparation

A health preserving pharmaceutical preparation comprising: 20 parts of ginseng, 35 parts of lily, 25 parts of fructus amomi and 20 parts of liquorice.

The ginseng and the fructus amomi are washed by water, dried, respectively crushed into superfine powder and sieved by a 400-mesh sieve to obtain ginseng powder and fructus amomi powder for later use.

Soaking lily and licorice in water for 3 hr, with the water amount being 5 times of the total weight of lily and licorice; after soaking, using a traditional baked earthen jar as a decocting container, decocting for 1 hour by slow fire in the decocting process, stopping decocting when the amount of the decoction is 15% of the amount of the added water, separating out the decoction, adding water into the decoction dregs again for decocting, wherein the decocting condition is the same as that of the first decocting, and mixing the decoction obtained in the second decocting with the decoction obtained in the first decocting.

Concentrating the obtained medicinal juice to obtain extract, adding the obtained Ginseng radix powder and fructus Amomi powder, mixing, and vacuum drying at a temperature below 50 deg.C to obtain granule preparation.

Third, record of clinical treatment data of health preserving pharmaceutical preparation

The treatment data of the health preserving pharmaceutical preparation are shown in table 1.

TABLE 1 clinical treatment data for health preserving pharmaceutical preparations

The details of the situations before and after taking by a plurality of patients with the health-preserving medicinal preparation are listed as follows: (the product is a health preserving medicine granule preparation prepared by the scheme, 6g of the preparation is taken in each bag with warm water)

1. The tumor postoperative radiotherapy and chemotherapy period patients:

case 1: mr. prune, male, age 65. The disease is characterized in that the disease is cured in the east of living areas of a combined fertilization and chemical plant, the disease has a smoking history of more than 40 years, the disease is cured by white sticky plague after getting up in the morning for a long time, the outbreak of external infection continues to be expectorated continuously in the last ten days of 3 months in 2011, the disease is aggravated at night, blood streaks are contained in sputum in the morning, antiviral and antibacterial drugs are taken orally and are used together for treatment for two weeks, the symptoms are improved to some extent, the chest and the back are dull and oppressed, the fatigue, the dry mouth and the inappetence continue to appear, the department of hospital is transferred to the province, the middle lobe of the right lung and the upper lobe of the left lung respectively show irregular infiltration shadows, the adenocarcinoma is diagnosed by the examination. Patients are emaciation, poor sleep, dry sputum with little sputum, chest distress, palpitation, hypodynamia, spontaneous perspiration, dry mouth, only eating semifluid diet and unsmooth defecation. The health-preserving medicinal preparation is orally taken 2 hours after breakfast and supper, one bag is respectively taken with warm boiled water, the conscious sleep is improved after one week, the chest distress and palpitation are relieved, a little white phlegm, hypodynamia, spontaneous perspiration are improved, the mouth is dry, half bowl of soft rice can be eaten, the soft rice can be put down to a bed to brush teeth and wash faces, the people can walk at home slowly, and the defecating is smooth. After being taken continuously, the diseases disappear after one year, no tumor relapse is seen through lung CT double diagnosis, and the life is still healthy.

Case 2: old women, 51 years old, live in the province and the Living hall dormitory of Anhui Hui. In 10 months of 1989, the patient feels aversion to cold, is worried and irritative in the afternoon, has poor sleep, starts in the morning, is dry and bitter in mouth, has reduced meal volume and is reduced in weight because the left breast is distended and painful and the nipple is itchy and yellow brown liquid. Go to the outpatient department of mammary gland department in the institute of Security and medical science, confirm the diagnosis of the middle stage of breast cancer through the biopsy and discharge through the operation and chemotherapy. The patients have dull complexion, alopecia, marasmus, insomnia, and difficulty in eating rice water or batter, and have symptoms of stomach pain and distention, morning fatigue, nausea, emesis, dry mouth, poor drinking water, and asthenia. The product is administered with warm boiled water in the morning for one bag; A bag is drunk 2 hours after meal. Nausea in the morning after one week, and vomiting after meal. The thirst is improved, and the nausea is avoided after drinking 300 ml of warm boiled water before and after each meal, and people want to eat the cooked rice. After two weeks, the user can sleep for 3 hours at night after the sleep is improved, the discomfort of stomach dull pain and fullness is improved, and the user can walk slowly. After one month, the flour becomes moist and has better spirit, the stomach discomfort is greatly reduced after sleeping for about 5 hours, and one bowl of porridge and one egg in the morning are eaten separately; adding a bowl of soup and dish in half a bowl of rice at noon; and a small bowl of noodles at night. It is healthy up to now.

2. Diabetic type ii patients:

case 1: mr. Tang Dynasty, 47 years old, Yifei Forklift sales company stay outside manager, 6 months dizziness, palpitation, soreness and weakness of waist and knees, easy hunger, thirst, spontaneous perspiration, easy waking up at night can not fall asleep for more than two years, through the tests of blood test, electrocardio and B ultrasonic examination in the department of endocrinology of the department of medical university and institute of medical university, the diagnosis of diabetes type II and insulin insufficiency are confirmed, insulin and metformin are adopted for oral sugar control treatment for one year, the patient still feels tired and weak, has meals, exercise and frequent spontaneous perspiration at night, the patient has a dry mouth after morning and meals, the patient has a heavy drink, the patient is easy to starve, feel distending in the stomach, feeling the stomach, and feeling fullness after meals, the stomach is full of belching, the stool is dry and uneven, and turbid urine foams are many. The product is taken with warm boiled water 2 hours before breakfast and after dinner every day. Sleep is improved at night after one week, after a meal, stomach fullness and warm air are better, thirst is relieved, and fatigue, spontaneous perspiration and abnormal stool are better. After drinking for one year, all symptoms disappear.

Case 2: zhao women, 39 years old, get fat to the adult train conductor. In 2016, palpitation, chest distress in 5 months, poor sleep (about 3 hours), dysphoria, thirst, polydipsia, anorexia, tiredness, hypomenorrhea, and loose stool. The syndrome of diabetes mellitus ll type, deficiency of both heart and spleen and dysfunction of spleen and stomach are confirmed by the auxiliary hospital physical examination of Anhui Chinese medicine university. The oral liquid of metformin and radix astragali is administered for one year. Blood sugar control is unstable, the stomach is still distended and uncomfortable, fatigue, dry mouth and thick stool occur in the morning, sleep is still poor at night, tiredness occurs in the morning, and the menstrual flow is the same as before. The product is taken with warm boiled water in the morning and 2 hours after supper. After one week, people feel sleepy after 10 hours, if the people are not in a car, the people can sleep for about 4 hours at home, fatigue is relieved in the morning, dry mouth is relieved, and after lunch or dinner, stomach fullness and warm air are relieved, and stool consistency is improved. After one month, the patient feels moist, has a palpitation and chest distress improving effect, is good in sleep and fatigue, has a stomach fullness and discomfort, relieves the heat, has a large dry mouth, obviously improves appetite, has a soft, non-sticky and smooth stool shape, and slightly increases the menstrual flow by one day and is red. The blood sugar is stable in the morning and at night after being continuously drunk for one year, and all symptoms disappear.

3. Sub-health syndrome user:

case 1: song classmate, male, 24 years old, university of Chinese science and technology, biological system research student. In 8 months in 2019, the glasses are broken once when the user sleeps in the morning and goes to an experimental class, the root of the nose is scratched, and the test tube which is not taken stably falls and is broken once. The oral cavity is dry and the drinking is favored all day long, the mouth and tongue are sore and painful intermittently, the halitosis, the stomach dull pain is accompanied with burning sensation, the fullness and discomfort after eating are caused, the hair is washed and the hair loss is more before half a year, the white bits and the pruritus of the skin of the limbs and the back are generated before the spring festival for more than four months, and the improvement is realized only in summer. In life, breakfast is rarely eaten, people are hot and heavy in mouth, and sleep from early middle school to 1 o' clock at midnight. The health-preserving medicinal preparation is taken with warm boiled water for 2 hours after being taken with an empty stomach and in the morning. One week later, drowsiness, dry mouth, upset stomach, and appetite improvement. The symptoms disappear after the drinking for three months.

Case 2: korean female, 29 years old, Yili Si Geba entertainment city leading manager. In 2017, the patient is diagnosed with long-term fatigue, alopecia, dry mouth, repeated attack of aphtha, pain, skin dryness and pruritus in nearly two months and amenorrhea for three months. The patients have a dull complexion, chloasma on the forehead and the cheeks on the right cheeks, pale lips, pale and swollen tongue, white and dry fur, and deep, thready and rapid pulse. The health-preserving medicinal preparation is drunk in a bag with warm boiled water respectively in an empty stomach in the morning and 2 hours after supper, the conscious spirit is obviously improved after one week, and the skin is dry and the itch, the mouth is dry, and the mouth sore pain is relieved. The three-month re-diagnosis is continued to be drunk, the menstruation is recovered, and the rest symptoms disappear.

4. The patients with cough and asthma:

case 1: mr. Meng, 58 years old, was once a warehouse manager of the combined fertilizer and meat factory, and was responsible for the work of delivering and warehousing the cold storage food. Cough and asthma secondary to heatstroke in 6 months of 1986, white and sticky cough with little foam phlegm, palpitation, chest distress and discomfort, frequent occurrence in winter and spring, aggravation of cough and asthma at night, spontaneous perspiration, fatigue, hypodynamia, inappetence and dry stool. When the doctor is in the clinic, the back of the bow is in the consulting room, the face is yellow, the lips are dark purple, the tongue is pale, the tongue tip is petechia, the coating is thin and dry, and the pulse is deficient and unsmooth. The health-preserving medicinal preparation is taken with warm boiled water one bag each in morning on an empty stomach and hours after meals. One week later, the patient feels palpitation and chest distress is relieved, appetite is increased, and the mouth dryness and dry stool are improved. After drinking for a year, the cough and asthma time is obviously shortened in winter and spring today, little expectoration is easy to be expectorated, and the usual time is basically the same as that of a normal person.

Case 2: liu women, 41 years old, Anhui Jiatong tire company quality inspector. In 2013, the patient is cured by western medicine infusion treatment due to upper respiratory tract infection with fever and yellow sticky phlegm with chest distress and discomfort in 11 months. But the cough in the morning and at night is a few sounds, and a little white sticky phlegm is cough. Cough in 3 months in 2014 obviously increases the symptoms of chest distress with asthma, obvious feeling of gradual sweating of the back during cough, sweating at the head during eating, spontaneous sweating during sleeping, dry mouth and nose in the morning, and good appetite, hypodynamia and dry stool. The face is lusterless, the lips are pale white, the tongue is thin and dry, the coating is thin and dry, and the pulse is weak. The product is administered after breakfast and fasting in the morning and supper, and is taken with warm boiled water. After one week, the feeling of chest oppression is relieved, the mouth and the nasal cavity are moistened, the appetite is increased, the spirit is good, and the cough is reduced. The beverage can be drunk for one year. All symptoms disappear.

5. Patients with chronic gastritis and gastric ulcer:

case 1: pengsheng, 37 years old, Anhui Zhongqi group taxi company taxi drivers. Half of the iced watermelons are eaten after work in 9 months in 2012 because of hot weather, the hearts of the stomach occur after one week, nausea occurs when teeth are brushed in the morning, dull pain in the stomach gradually occurs, the hearts burn before meals, and the people feel distending pain and discomfort after meals, and the weight is reduced, tired and poor in sleep after one year. The patients have poor spirit, emaciation, yellow complexion, white and moist coating, and deep, slow and astringent pulse. The health-preserving medicinal preparation is taken with warm boiled water one bag each in morning on an empty stomach and hours after meals. One week later, the user does not feel tired when driving the toothbrush, and the nausea and heartburn of the toothbrush are relieved in the morning, so that the stomach is relieved from dull pain and fullness. After drinking for three months, all symptoms disappear.

Case 2: a lady, 26 years old, a joint-fatness, Shunfeng express company clerk. In 2018, the patient often can not eat the food on time due to busy business, and the patient is diagnosed with gastric ulcer by stomach spasm and pain accompanied by vomit due to sudden fatigue, secondary dizziness and black asphalt excrement hospitalization. The patients have pale complexion, pale lips, anemia, dry tongue with little body fluid, and weak and soft pulse. The health-preserving medicinal preparation is taken with warm boiled water one bag each in morning on an empty stomach and hours after meals. After one week, dizziness is improved, spirit is improved, and the patient can be healed after drinking for one month.

6. The patients who are drunk with alcoholic liver:

case 1: mr. Wang, 53 years old, Anhui electric company service department manager. In 2007, chronic cholecystitis, gastritis and alcoholic hepatitis can be detected in the first hospital in the mixed fertilizer market due to vague pain, hypodynamia, inappetence, dry mouth, bitter taste and insomnia on the right side in 6 months. The patients have a dark purple complexion, dry lips, halitosis, red tongue, thin yellow and dry coating, and deep and soft pulse. The health-preserving medicinal preparation is taken in a bag with warm boiled water in the morning and 2 hours after meals. After one week, the patient feels better sleep, and the patient suffers from hypodynamia, dull pain in the right upper abdomen, dry mouth and inappetence. After drinking for three months, all symptoms disappear.

Case 2: ginger women, 38 years old, Anhui Gujing tribute wine, and manager of the Ministry of the Fertilizer market. In the long-term drinking history in 7 months in 2018, chronic gastritis and alcoholic hepatitis are confirmed and diagnosed by the physical examination in the hospital 901 of the liberation army due to dizziness, memory decline, vision decline, dry eyes, astringency and pain, stomach distension, upset, inappetence and easy fatigue. In the clinic, there are lusterless complexion, chloasma on the left and right cheeks, pale purple lips, thin and red tongue with thin, yellow, dry and scanty saliva coating, and deep and deficient pulse. The health-preserving medicinal preparation is taken with warm boiled water for one bag in the morning and evening and hours after meal. After one week, the face turns moist, the stomach is noisy, the appetite is not improved, the dry mouth is relieved, and the spirit is improved. After drinking for three months, all symptoms disappear.

According to the clinical treatment data and records, the health-care medicinal preparation prepared and processed by the scheme is suitable for long-term dietary therapy conditioning of the crowd with tumor postoperative radiotherapy and chemotherapy, diabetes type II, chronic cough and asthma, long-term stay-up sub-health syndrome, chronic gastritis, gastric ulcer, alcoholism and alcoholic liver. The medicine has no side effect and no dependence, is a health-preserving health-care medicine which is taken by the majority of people for a long time and has no disease and no consideration for the disease.

Claims

1. A health preserving pharmaceutical preparation is characterized in that: the composition comprises the following components in parts by weight: 15-30 parts of ginseng, 20-50 parts of lily, 10-40 parts of fructus amomi and 15-30 parts of liquorice.

2. A method for processing the health preserving pharmaceutical formulation as claimed in claim 1, comprising the steps of:

3. The method for processing a health preserving pharmaceutical preparation according to claim 2, characterized in that: in the step (1), the ginseng and the fructus amomi are washed by water and dried before being crushed.

4. The method for processing a health preserving pharmaceutical preparation according to claim 2, characterized in that: in the step (2), before the decoction in water, the lily and the liquorice are soaked in water for 2-4 hours, and the water adding amount is 4-6 times of the total mass of the lily and the liquorice.

5. The method for processing a health preserving pharmaceutical preparation according to claim 2, characterized in that: in the step (2), the decoction water is water in the soaking process.

6. The method for processing a health preserving pharmaceutical preparation according to claim 2, characterized in that: in the step (2), a crock is used as a decocting container, slow fire is adopted for decocting for 1-1.5 hours in the decocting process, the decocting is stopped when the amount of the decoction is 10-20% of the amount of the added water in the decocting process, and the decoction is separated.

7. The method for processing a health preserving pharmaceutical preparation according to claim 2, characterized in that: in the step (2), the decoction process is carried out twice, after the first decoction is finished and the decoction is separated out, 4-6 times of water by mass is added into the medicine residues, the decoction process is repeated, and the decoction which is separated out for the second decoction is mixed with the decoction which is obtained by the first decoction.

8. The method for processing a health preserving pharmaceutical preparation according to claim 2, characterized in that: in the step (3), the low-temperature drying is vacuum drying in a low-temperature environment of less than 50 ℃.