CN111514075B

CN111514075B - Sunscreen composition and application thereof

Info

Publication number: CN111514075B
Application number: CN202010497122.1A
Authority: CN
Inventors: 郝姗姗; 肖艳皎; 岳玉荣; 钟敏; 韩雅慧
Original assignee: Beijing Silian Pharmaceutical Industry Co ltd
Current assignee: Beijing Silian Pharmaceutical Industry Co ltd
Priority date: 2020-06-03
Filing date: 2020-06-03
Publication date: 2022-12-13
Anticipated expiration: 2040-06-03
Also published as: CN111514075A

Abstract

The invention relates to the technical field of daily chemical products, and discloses a sunscreen composition and application thereof. The sunscreen composition comprises a cistanche extract, a sage seed extract and a turmeric root extract. According to the invention, three traditional Chinese medicine functional components of a cistanche extract, a sage seed extract and a turmeric root extract are selected, so that the traditional Chinese medicine-containing sunscreen composition with more remarkable sunscreen effect and whitening, moisturizing and anti-wrinkle effects is obtained. On the basis, the madecassoside, the tocopherol and the shea butter are added to synergistically enhance the effects of various aspects. The composition can be matched with an auxiliary agent in the field of daily chemical products to prepare daily chemical products integrating sun protection, whitening, moisture retention and wrinkle resistance, meets the increasingly diversified requirements of consumers, and has wide application prospects.

Description

Sunscreen composition and application thereof

Technical Field

The invention relates to the technical field of daily chemical products, and particularly relates to a sunscreen composition and application thereof.

Background

As early as 20 years ago, developed countries such as europe and the united states began to be aware of the effects of radiation on the skin. Sunlight is an indispensable substance for life and growth of everything in the world, and proper ultraviolet radiation is beneficial to human health. Not only can accelerate blood circulation and help to synthesize vitamin D to promote the absorption of calcium ions, but also can calm people. However, excessive ultraviolet light can cause various skin injuries and harm human bodies.

Ultraviolet rays in sunlight are classified into short-wave (UVC, 180-280 nm), medium-wave (UVB, 280-320 nm) and long-wave (UVA, 320-400 nm) ultraviolet rays. Wherein UVC is almost completely absorbed while passing through the ozone layer and only UVB, UVA reach the ground. Ultraviolet radiation can cause various biological effects to the skin, mainly showing four aspects. (1) Sunburn reaction: including sunburn caused by UVB and tanning reactions caused by UVA and UVB. (2) Immunosuppressive action: UVA and UVB trigger immune suppression reaction within a certain time. (3) Photo-aging action: chronic uv irradiation causes the skin to react chronically, mainly manifested as photoaging, in which UVA plays an important role. Photoaged skin appears as rough, loose, atrophic, deeper and thicker wrinkles, visible irregular pigmentation, telangiectasia, and the like. (4) The light-induced cancer effect is as follows: UVA, UVB in the sunlight are important causative factors of pigmented and non-pigmented skin cancers.

Therefore, people need to pay attention to sun protection in daily life, wear protective clothes and caps and use sun-protection products for external use to strengthen light protection, so that the damage to the human body is reduced as much as possible. In recent 20 years, various sunscreens have been developed and added to cosmetics to achieve a protective effect to delay the intensity of sunlight on the skin. At present, sunscreen agents in the sunscreen cosmetics in the market, including chemical sunscreen agents and physical sunscreen agents, have certain irritation, so that the application of the sunscreen agents is limited. The traditional Chinese medicine sun-screening agent has high safety and the characteristics of skin care, whitening and anti-aging, and has wide development prospect.

Cistanche deserticola is a plant of Orobanchaceae, and is sweet and salty in taste, warm in nature, and enters kidney and large intestine meridians. Has the effects of tonifying kidney, supporting yang, and loosening bowel to relieve constipation. In fact, the medicine is not only a good medicine for tonifying the kidney and relaxing the bowels, but also a commonly used product for preserving health, resisting aging and beautifying. Records of the old on the aspects of health preservation and beauty treatment of the cistanche deserticola mainly include: the health care product has the effects of losing weight after long-time taking, moistening the five internal organs, growing muscle, benefiting marrow, nourishing the skin, prolonging life, treating female metrorrhagia, tonifying yang, resisting twice daily, greatly tonifying, replenishing vital essence and eliminating rancidity, blackening the face, resisting fatigue and the like.

Through research in recent 30 years, the phenylethanoid glycosides in the cistanche deserticola extract are proved to have obvious antioxidation, can remove various free radicals such as superoxide radical, hydroxyl free radical and the like, and improve the activity of antioxidant enzymes in organisms. The phenylethanoid glycosides have been shown to inhibit tyrosinase activity and have skin whitening effects.

Meanwhile, the phenylethanoid glycoside has a conjugated system in a molecular structure, has a good absorption effect on ultraviolet rays and can better prevent and relieve the damage of ultraviolet radiation to the skin, which is reported by documents and patents.

The sun-screening product containing the cistanche extracts prepared in the prior art is mainly prepared from the single cistanche extracts, is single in functional component and insufficient in efficacy, needs to be added with high content of the cistanche extracts to achieve the effect, is high in cost, is deep in color, and is difficult to meet the current requirements of consumers on multi-effect sun-screening products.

Patent application CN105125430A discloses a group of preparations with sunscreen and repair of skin damage by uv rays consisting of five natural antioxidant ingredients of coenzyme Q10, lipoic acid, glycyrrhizic acid, vitamin E and vitamin C. The preparation can also be added with plant sunscreen agent, such as Ginseng radix, radix astragali, scutellariae radix, aloe, cistanchis herba, rhizoma Kaempferiae, curcuma rhizome, and extracts and effective components of these Chinese medicinal materials. Said invention discloses that cistanche deserticola can be used for sun-screening preparation, but it can be seen from its embodiment that cistanche deserticola is not really utilized, and it finally uses the combination of coenzyme Q10, lipoic acid, glycyrrhizic acid, vitamin E and vitamin C. However, the combination of the preparation is chemical components, the skin nourishing effect is poor, and coenzyme Q10 which is one of the key components is unstable, easy to discolor and difficult to control the quality.

Disclosure of Invention

In view of the above, the present invention provides a sunscreen composition, which has a more significant sunscreen effect, and has a higher SPF value and PFA value;

another object of the present invention is to provide a sunscreen composition, which has more significant moisturizing, anti-wrinkle and whitening effects;

another object of the present invention is to provide a sunscreen composition, which can synergistically enhance the effect of physical or chemical sunscreen agents, reduce the kinds and amounts of sunscreen agents, and improve the safety of sunscreen cosmetics;

another object of the present invention is to provide the use of the above sunscreen composition in the preparation of related daily chemical products (e.g. sunscreen, whitening, moisturizing, anti-wrinkle).

In order to achieve the above purpose, the invention provides the following technical scheme:

a sunscreen composition comprises Cistanchis herba extract, herba Salvia officinalis seed extract and Curcuma rhizome extract. The main effective component of the cistanche deserticola extract is total glucosides of cistanche deserticola; the main effective component of the sage seed extract is carnosol which is a characteristic component of sage; the main effective component of the turmeric root extract is curcumin;

the cistanche extract, the sage seed extract and the turmeric root extract are preferably alcohol extracts, and more preferably ethanol extracts; wherein the ethanol is preferably 1-100% ethanol, more preferably 40-100% ethanol, and specifically can be 40% ethanol, 50% ethanol, 60% ethanol, 70% ethanol, 80% ethanol, 90% ethanol or anhydrous ethanol.

The composition is scientifically proportioned and comprises 30-70 parts of cistanche extract, 10-40 parts of turmeric root extract and 10-40 parts of sage seed extract by weight, so that the composition achieves a remarkable sunscreen effect through synergism, has the effects of moisturizing, resisting wrinkles and whitening, and can improve the effectiveness of sunscreen cosmetics.

In a specific embodiment of the invention, the cistanche salsa extract is 30 parts, 50 parts or 70 parts by weight; the weight part of the turmeric root extract is 10 parts, 25 parts or 40 parts; the weight parts of the sage seed extract are 10 parts, 25 parts or 40 parts;

specifically, the present invention provides the following sunscreen compositions:

(1) 50 parts of cistanche extract, 25 parts of turmeric root extract and 25 parts of sage seed extract;

(2) 30 parts of cistanche deserticola extract, 10 parts of turmeric root extract and 10 parts of salvia officinalis seed extract;

(3) 70 parts of cistanche deserticola extract, 40 parts of turmeric root extract and 40 parts of sage seed extract;

preferably, the sunscreen composition further comprises 0.3-0.8 weight parts of tocopherol, 0.5-5 weight parts of madecassoside and 10-40 weight parts of shea butter, and the effects of the sunscreen composition are further improved by further adding madecassoside, tocopherol and shea butter.

In a particular embodiment of the invention, tocopherol is present in an amount of 0.3, 0.5, 0.75 or 0.8 parts by weight; 0.5, 2.5, 3.75 or 5 parts of madecassoside; the shea butter accounts for 10 parts, 25 parts, 37.5 parts or 40 parts by weight;

specifically, the invention provides the following madecassoside, tocopherol and shea butter combinations:

(1) 0.5 part of tocopherol; 2.5 parts of madecassoside; 25 parts of shea butter;

(2) 0.75 part of tocopherol; the weight portion of the madecassoside is 3.75; 37.5 parts of shea butter;

(3) 0.8 part of tocopherol; 5 parts of madecassoside; 40 parts of shea butter;

(4) 0.3 part of tocopherol; 0.5 part of madecassoside; the shea butter accounts for 10 parts by weight;

preferably, the weight ratio of the total dosage of the cistanche extract, the sage seed extract and the turmeric root extract to the total dosage of the madecassoside, the tocopherol and the shea butter is controlled to be between 100 and 28 and 42, the effect is better, the weight ratio of the cistanche extract, the sage seed extract and the turmeric root extract is preferably 3 to 7.

In the sunscreen effect test of the sunscreen composition, the aloe extract, the vitamin C, the asiaticoside and other components commonly used in sunscreen compositions are adopted to replace the sage seed extract, the tocopherol and the madecassoside to form a comparative example to compare the sunscreen, whitening, moisturizing and anti-wrinkle aspects of the sunscreen composition with the composition disclosed by the invention, and the result shows that the sunscreen composition disclosed by the invention has better effect than each pair of proportions, and shows that the combination of the cistanche extract, the sage seed extract and the curcuma root extract can obtain good sunscreen effect. The sun-screening, whitening, anti-wrinkle and moisturizing effects of the composition are better than those of the non-added sun-screening composition by further adding the madecassoside, the tocopherol and the shea butter, and the effects of all aspects are further improved. Meanwhile, the related results also show that the excellent sunscreen effect can be obtained only by combining the cistanche extract, the sage seed extract and the turmeric root extract or further combining the cistanche extract, the sage seed extract and the turmeric root extract with the madecassoside, the tocopherol and the shea butter, and the effect is reduced due to the replacement of the components in the cistanche extract, the sage seed extract and the turmeric root extract.

Based on the technical effects, the invention provides the application of the sun-screening composition in preparing daily chemical products with one or more effects of sun screening, whitening, moisturizing and wrinkle resistance; the daily chemical product is preferably a cosmetic, such as cream, emulsion, water and the like for sunscreen, whitening, moisturizing and anti-wrinkle.

Depending on the application, the present invention provides a daily chemical product comprising the sunscreen composition of the present invention and an auxiliary agent which can be used in the daily chemical product.

Preferably, the auxiliary agent is one or more of a sunscreen agent, a skin conditioner, an emulsifier, a thickener, a chelating agent and a solvent.

Wherein the sunscreen agent is one or more selected from titanium dioxide, zinc oxide, ethylhexyl methoxycinnamate, butyl methoxydibenzoylmethane, 4-methylbenzylidene camphor, benzophenone-3, ethylhexyl salicylate, bis-ethylhexyloxyphenol methoxyphenyl triazine;

the skin conditioning agent is selected from one or more of isododecane, isohexadecane, cyclomethicone, squalane, caprylic/capric triglyceride, jojoba seed oil, sea buckthorn oil, dioctyl carbonate, cyclopentademethicone, PEG-10 dimethicone, C12-15 alcohol benzoate, ethylhexyl glycerol, octyldodecanol pivalate, butyl octanol salicylate, dipotassium glycyrrhizinate, p-hydroxyacetophenone, stearyl glycyrrhetinate, hydrolyzed hyaluronic acid, sodium hyaluronate, acetylated sodium hyaluronate, panthenol, allantoin and betaine;

the emulsifier is one or more selected from PEG-100 stearate, glycerol stearate, potassium cetyl phosphate, cetostearyl alcohol, sorbitan sesquioleate, polyglycerol-6 polyricinoleate, aluminum stearate, polyhydroxystearic acid, stearic acid and sodium stearyl glutamate;

the thickening agent is selected from one or more than two of xanthan gum, carbomer, methyl methacrylate cross-linked polymer, polyester-5, polyacrylate cross-linked polymer-6, hydroxypropyl methyl cellulose stearyloxy ether, ammonium acryloyl dimethyl taurate/VP copolymer, aluminum oxide and silica;

the chelating agent is one or more than two of disodium EDTA, trisodium EDTA and tetrasodium EDTA;

the solvent is one or more than two of water, butanediol, 1, 2-hexanediol, tert-butanol, 1, 2-pentanediol and 1, 3-butanediol.

Preferably, the daily chemical product comprises the sun-screening composition, a sun-screening agent, a skin conditioning agent, an emulsifier, a thickening agent, a chelating agent and a solvent, wherein the parts by weight of the components are as follows:

further preferably, the weight parts of the components are as follows:

in a particular embodiment of the invention, the particular adjuvants are selected as in table 1 below:

TABLE 1

In addition, the invention also provides a preparation method of the daily chemical product, which comprises the steps of selecting an auxiliary agent to prepare a water phase and an oil phase, homogenizing and emulsifying the water phase and the oil phase, adding the sunscreen composition, and uniformly mixing to obtain the daily chemical product.

In the embodiment of the invention, the preparation process is specifically illustrated by taking the additives listed in table 1 as examples:

step 1, mixing, stirring and dissolving titanium dioxide, ethylhexyl methoxycinnamate, zinc oxide, ethylhexyl salicylate, C12-15 alcohol benzoate, caprylic/capric triglyceride, aluminum stearate, polyhydroxystearic acid, stearic acid and aluminum oxide in advance until the mixture is transparent, and heating the mixture to 85-90 ℃ to obtain an oil phase;

adding water, butanediol, 1, 2-hexanediol, 1, 2-pentanediol, sodium stearyl glutamate, silica, polyester-5, polyacrylate cross-linked polymer-6, hydroxypropyl methyl cellulose stearyl oxy ether, ammonium acryloyl dimethyl taurate/VP copolymer and EDTA disodium into an emulsifying machine, stirring and mixing uniformly, and heating to 85-90 ℃ to obtain a water phase;

step 2, pumping the oil phase into the water phase, homogenizing and emulsifying, homogenizing for 8-12 minutes, stirring and mixing uniformly, and preserving heat for 25-35min;

step 3, after homogenizing and emulsifying, cooling to 40-50 ℃, adding the cistanche extract, the turmeric root extract, the sage seed extract, the tocopherol, the madecassoside and the shea butter, and stirring and mixing uniformly;

and 4, slowly cooling to 33-37 ℃, filtering and discharging.

Compared with the non-added group, the daily chemical product added with the sunscreen composition can well and synergistically enhance the effect of a physical or chemical sunscreen agent, reduce the types and the using amount of the sunscreen agent and improve the safety of the sunscreen cosmetic.

According to the technical scheme, the traditional Chinese medicine-containing sun-screening composition with more remarkable sun-screening effect, whitening effect, moisturizing effect and anti-wrinkle effect is obtained by selecting three traditional Chinese medicine functional components of the cistanche extract, the sage seed extract and the turmeric root extract. On the basis, the madecassoside, the tocopherol and the shea butter are added to synergistically enhance the effects of various aspects. The composition can be matched with an auxiliary agent in the field of daily chemical products to prepare daily chemical products integrating sun protection, whitening, moisture retention and wrinkle resistance, meets the increasingly diversified requirements of consumers, and has wide application prospects.

Detailed Description

The invention discloses a sunscreen composition and application thereof, and can be realized by appropriately improving process parameters by referring to the content in the text by a person skilled in the art. It is expressly intended that all such similar substitutes and modifications which would be obvious to one skilled in the art are deemed to be included in the invention. While the compositions and uses of this invention have been described in terms of preferred embodiments, it will be apparent to those skilled in the art that the techniques of this invention may be practiced and used with modification, or with appropriate modification, and combinations of the compositions and uses described herein without departing from the spirit, scope, and spirit of the invention.

In order to ensure the comparability of the test, if not stated, the other test conditions are consistent except for the proper differences of the groups, such as the external environment of the test, the source and quality of the raw materials, the obtaining method of the extract, the preparation process and the like.

The cistanche extract, the sage seed extract and the turmeric root extract can be obtained by extracting according to the following methods:

cistanche deserticola extract: extracting with 20 times of 40% ethanol under reflux for 1 time and 2 hr, concentrating the extractive solution under reduced pressure until no ethanol smell exists, and drying the concentrated solution at 60 deg.C to obtain Cistanchis herba extract.

Sage seed extract: extracting with 25 times of 50% ethanol under reflux for 3 times (1 hr each time), concentrating the extractive solution under reduced pressure until ethanol smell disappears, and drying the concentrated solution at 60 deg.C to obtain herba Salvia officinalis seed extract.

Turmeric root extract: extracting with 10 times of anhydrous ethanol under reflux for 1 time for 1.5 hr, concentrating the extractive solution under reduced pressure until no ethanol smell exists, and drying the concentrated solution at 60 deg.C to obtain Curcuma rhizome extract.

The sunscreen composition and the application thereof provided by the present invention are further described below.

Example 1: the sunscreen composition of the invention

1. Formulation(s)

TABLE 2

2. Comparative example

Comparative example 1: compared with formula 5, the aloe extract is used to replace the sage seed extract with the same dosage.

Comparative example 2: compared with formula 1, the aloe extract is used to replace the sage seed extract, and the asiaticoside is used to replace madecassoside, and the dosage is unchanged.

Comparative example 3: compared with formula 1, the aloe extract is used to replace the sage seed extract, and the vitamin C is used to replace the tocopherol, and the dosage is unchanged.

Wherein the aloe extract is prepared by ultrasonic extracting with 30 times of 50% ethanol for 30min, and filtering. Concentrating the extractive solution under reduced pressure until no ethanol smell exists, and drying the concentrated solution at 60 deg.C to obtain Aloe extract.

Example 2: comparative test of sun-screening and whitening, moisturizing and anti-wrinkle effects

1. Test for sunscreen Effect

Preparing a blank emulsion comprising an oil phase: 3 parts of cetostearyl alcohol, 2 parts of glyceryl stearate, 6.5 parts of white oil and 0.1 part of propyl hydroxybenzoate; water phase: 0.1 part of xanthan gum, 1.5 parts of potassium lauryl phosphate, 5 parts of glycerol, 0.15 part of methylparaben and 81.65 parts of water.

Formulations 1-5 of example 1 and comparative examples 1-3 were selected, and 98 parts of the blank emulsion were added to 2 parts of the test composition. The sunscreen effect of the product is tested according to the sunscreen cosmetic sun protection index test method (human body method) in technical Specification for cosmetic safety (2015 edition), and the test method is as follows:

sun Protection Factor (SPF): also known as the solar protection factor, indicates how high the sunscreen product can exert the sunscreen effect. The larger the SPF value, the better the sunscreen effect. It is determined based on the lowest erythemal dose (MED) of the skin. When the sunscreen is used, the minimum erythema dose of the skin increases, and the sun protection factor SPF of the sunscreen is:

the SPF index is useful for evaluating the protection against UVB.

Long-wave ultraviolet protection index (PFA value) of sunscreen cosmetic: also known as the UVA protection index. UVA in sunlight strikes the skin, primarily producing the physiological effects of skin darkening, measured as the minimum amount of sustained darkening (MPPD). MPPD is the minimum ultraviolet irradiation dose or the minimum irradiation time required for 2-4h after irradiation to produce slight blackening on the skin at the whole irradiation site.

The test results are shown in table 3:

TABLE 3

Product number	Formulation 1	Formulation 2	Formulation 3	Formulation 4	Formulation 5	Comparative example 1	Comparative example 2	Comparative example 3
									SPF value	15.2	13.9	11.6	11.5	9.1	4.5	3.5	3.6
PFA value	4.5	3.9	3.5	3.4	2.7	2.2	2.0	2.0

2. Moisturizing, anti-wrinkle and whitening human body sensory evaluation

Formulations 1-5 of example 1 and comparative examples 1-3 were selected, and 98 parts of the blank emulsion were added to 2 parts of the test composition. 240 female volunteer subjects with healthy skin and no history of skin allergy were selected to participate in the trial, and all volunteer subjects were randomly divided into 8 groups of 30 subjects each. The tested samples are respectively tried by all groups of volunteer subjects for continuous use for one month, and after the trial, all the volunteer subjects self-evaluate the using effects of moisturizing, whitening and resisting wrinkles. According to the using effect, the score is between 0 and 9, the score is the best when 9 is used, and the score is the worst when 0 is used, and the average value is taken. The results of the experiment are shown in table 4:

TABLE 4

3. Conclusion

The effect of the formula 5 is superior to that of the comparative example 1, and the effect of combining the cistanche extract, the salvia seed extract and the turmeric root extract can obtain a good sunscreen effect. The effect of the formula 1-4 is better than that of the formula 5, which shows that the sun-screening effect of the composition is further improved by further adding the madecassoside, the tocopherol and the shea butter. Meanwhile, the effects of the formulas 1 to 4 are superior to those of the comparative examples 2 to 3, which shows that excellent sunscreen effect can be obtained only by combining the cistanche extract, the sage seed extract and the turmeric root extract with the madecassoside, the tocopherol and the shea butter, and the effect is reduced due to the replacement of the components in the extracts. The effect of the formula 1-2 is better than that of the formula 3-4, which shows that the weight ratio of the total dosage of the cistanche extract, the sage seed extract and the turmeric root extract to the total dosage of the madecassoside, the tocopherol and the shea butter is controlled between 100 and 28-42, so that better effect can be obtained. The effect of the formula 1 is better than that of the formula 2, and the weight ratio of the cistanche extract, the sage seed extract and the turmeric root extract is controlled to be 2. The result of human body sensory evaluation is the same as the trend of the sun-screening effect, and shows that the sun-screening composition provided by the invention has excellent sun-screening effect and also provides good moisturizing, anti-wrinkle and whitening effects.

Example 3: preparation of sun cream of daily chemical product

1. Formulation of

TABLE 5

2. Preparation method (if the formulation does not contain a certain component, the component is not added in the preparation process)

Step 1, mixing, stirring and dissolving titanium dioxide, ethylhexyl methoxycinnamate, zinc oxide, ethylhexyl salicylate, C12-15 alcohol benzoate, caprylic/capric triglyceride, aluminum stearate, polyhydroxystearic acid, stearic acid and aluminum oxide in advance until the mixture is transparent, and heating the mixture to 88 ℃ to obtain an oil phase;

adding water, butanediol, 1, 2-hexanediol, 1, 2-pentanediol, sodium stearyl glutamate, silica, polyester-5, polyacrylate cross-linked polymer-6, hydroxypropyl methyl cellulose stearyl oxy ether, ammonium acryloyl dimethyl taurate/VP copolymer and EDTA disodium into an emulsifying machine, stirring and mixing uniformly, and heating to 88 ℃ to obtain a water phase;

step 2, pumping the oil phase into the water phase, homogenizing and emulsifying, homogenizing for 10 minutes, stirring and mixing uniformly, and preserving heat for 30min;

step 3, after homogenizing and emulsifying, cooling to 45 ℃, adding the cistanche extract, the turmeric root extract, the sage seed extract, the tocopherol, the madecassoside and the shea butter, and stirring and mixing uniformly;

and 4, slowly cooling to 35 ℃, filtering and discharging.

3. Comparative example

Comparative example 4: in comparison with sunscreen 1, the composition of formulation 1 was replaced with the composition of comparative example 1 only, in the same amount.

Comparative example 5: in comparison with sunscreen 1, the composition of formulation 1 was replaced with the composition of comparative example 2 only, in the same amount.

Comparative example 6: compared with sunscreen 1, other conditions are the same as sunscreen 1 except that no sunscreen composition is added.

Example 4: sunscreen effect test and human body skin patch test of sunscreen cream

1. Test for sunscreen Effect

Referring to the procedure of example 2, the results are shown in Table 6:

TABLE 6

Product numbering	Sunscreen cream 1	Sunscreen cream 2	Sunscreen cream 3	Sunscreen cream 4	Comparative example 4	Comparative example 5	Comparative example 6
								SPF value	45	30	35	34	22	23	20
PFA value	10.3	8.5	9.2	9.0	5.4	5.2	4.3

2. Patch test on human skin

210 volunteers meeting the enrollment criteria were selected for participation in the trial and randomized into 7 groups of 30 individuals each. 0.025g of the sample was taken by a syringe and placed in a chamber of a spot test tape, and the spot test tape with the sample placed therein was immediately stuck to the normal skin of the left forearm from the lower part thereof in the longitudinal direction while gently pressing the chamber one by one to expel air and uniformly distribute the test substances. The test site is marked for easy observation. The patch was applied every 24 hours and was then peeled off for a half hour before examination according to the grading standards. The patch test was performed 6 times in total, and on day 6 after completion of the skin application, additional examination was performed to observe delayed reactions. The data is compared by using the last check result; the criteria for the skin irritation test are shown in table 7:

TABLE 7

The results are shown in Table 8:

TABLE 8

3. Conclusion

The spot-pasting test results of the sun-screening creams 1 and 4 are better than those of the sun-screening creams 2 and 3 and the comparative examples 4 to 6, which shows that the sun-screening composition of the invention can improve the safety of sun-screening cosmetics. The effects of the sunscreen creams 1 and 4 are superior to that of the sunscreen cream 2, 2 sunscreen agents are added into the sunscreen creams 1 and 4, and 4 sunscreen agents are added into the sunscreen cream 2, so that on the premise that the total dosage of the three sunscreen creams is the same, the sunscreen cream added with the composition of the formula 1 can reduce the types of the sunscreen agents compared with the composition of the formula 5. The effect of the sunscreen cream 1 is better than that of the sunscreen cream 3, the dosage of the sunscreen agent in the sunscreen cream 1 is 6 parts, and the dosage of the sunscreen agent in the sunscreen cream 3 is 12 parts, which shows that the sunscreen cream using the composition of the formula 1 can reduce the dosage of the sunscreen agent compared with the composition of the formula 5, and the effect is better. Sunscreen 1 showed superior efficacy to sunscreen 4, indicating that the combination of formula 1 of the present invention with titanium dioxide and ethylhexyl methoxycinnamate showed the best efficacy.

In addition, the trends in the results of the tests conducted using the compositions of formulas 2-4 were the same as the trends in the results of the tests conducted using the composition of formula 1.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims

1. A sunscreen composition is characterized by comprising, by weight, 30-70 parts of cistanche deserticola extract, 10-40 parts of sage seed extract and 10-40 parts of turmeric root extract.

2. A sunscreen composition is characterized by comprising, by weight, 30-70 parts of cistanche extract, 10-40 parts of sage seed extract and 10-40 parts of turmeric root extract, wherein the cistanche extract, the sage seed extract, the turmeric root extract, tocopherol, madecassoside and shea butter are contained.

3. The sunscreen composition of claim 2 comprising, in parts by weight, 0.3 to 0.8 parts tocopherol, 0.5 to 5 parts madecassoside, and 10 to 40 parts shea butter.

4. The sunscreen composition of claim 3 wherein the ratio of total amounts of cistanche extract, sage seed extract, turmeric root extract to total amounts of tocopherol, madecassoside, shea butter is 100 to 42 by weight.

5. Use of a sunscreen composition according to any of claims 1 to 4 in the manufacture of a daily use chemical product having one or more of sunscreen, whitening, moisturizing and anti-wrinkle effects.

6. A daily chemical product comprising the sunscreen composition according to any one of claims 1 to 4 and an auxiliary agent used in the production of the daily chemical product.

7. The daily chemical product according to claim 6, wherein the auxiliary agent is one or more of a sunscreen agent, a skin conditioner, a solvent, a thickener, a chelating agent, and an emulsifier.

8. The method for producing a daily chemical product according to claim 6, wherein the auxiliary is selected to prepare an aqueous phase and an oil phase, the aqueous phase and the oil phase are homogenized and emulsified, and then the sunscreen composition according to any one of claims 1 to 4 is added and mixed uniformly to obtain the daily chemical product.