Nothing Special   »   [go: up one dir, main page]

CN111380782A - Sensor alloy suspension wire and thrombelastogram instrument with same - Google Patents

Sensor alloy suspension wire and thrombelastogram instrument with same Download PDF

Info

Publication number
CN111380782A
CN111380782A CN201910442552.0A CN201910442552A CN111380782A CN 111380782 A CN111380782 A CN 111380782A CN 201910442552 A CN201910442552 A CN 201910442552A CN 111380782 A CN111380782 A CN 111380782A
Authority
CN
China
Prior art keywords
suspension wire
sensor
alloy suspension
alloy
wire
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201910442552.0A
Other languages
Chinese (zh)
Other versions
CN111380782B (en
Inventor
马玉坤
张娟丽
于婷
李伟甲
孟兵涛
赵晓培
杨会
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhengzhou Puwan Medical Technology Co ltd
Original Assignee
Zhengzhou Puwan Medical Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhengzhou Puwan Medical Technology Co ltd filed Critical Zhengzhou Puwan Medical Technology Co ltd
Priority to CN201910442552.0A priority Critical patent/CN111380782B/en
Publication of CN111380782A publication Critical patent/CN111380782A/en
Application granted granted Critical
Publication of CN111380782B publication Critical patent/CN111380782B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Strength Of Materials By Application Of Mechanical Stress (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Ropes Or Cables (AREA)

Abstract

The invention relates to a sensor alloy suspension wire and a thrombelastogram instrument with the same. The alloy suspension wire is a copper-nickel-zinc alloy wire with a circular groove structure in the middle, and has good elasticity, chemical resistance, fatigue resistance and stability. By means of the special performance of the alloy suspension wire, the accuracy and the stability of the detection result of the thromboelastogram instrument are ensured.

Description

Sensor alloy suspension wire and thrombelastogram instrument with same
Technical Field
The invention belongs to the field of blood detection, and particularly relates to a sensor alloy suspension wire and a thromboelastogram instrument with the suspension wire.
Background
The thromboelastogram instrument is a blood coagulation function analyzer for real-time, dynamic and continuous monitoring of the whole process of platelet aggregation, blood coagulation, fibrinolysis and the like, and can be used for qualitative or quantitative analysis of the blood coagulation condition of a patient.
The principle of the thromboelastogram instrument for detecting the blood coagulation function is that a sensor probe is immersed in a blood sample, viscous force exists between the blood sample and the sensor probe, the viscous force changes along with changes of platelet aggregation, blood coagulation, fibrinolysis and the like, a sensor suspension wire generates torsional deformation under the action of the viscous force, the torsional deformation is detected by a detection unit and is converted into an electric signal to be fed back to a control system, the control system carries out operation after receiving the changed signal, and an operation result is displayed on a computer screen in the form of a curve graph and real-time data.
In the detection process, the stability of the relative motion between the blood sampling cup tray and the detection sensor plays a critical role. Because the tray of the blood sampling cup is used as a rotor, the detection sensor is used as a stator, the rotation angle range of the rotor is 4-5 degrees, and how to sharply and accurately identify the change of the viscous force of the blood sample in the angle range depends on the performance of a suspension wire which is the most precise part in the thrombelastography instrument.
The suspension wire is a conductor of viscous force between the sensor probe and blood, and the accuracy of data acquisition has very high dependence on the performance of the suspension wire. The suspension wire is a metal wire which is processed precisely, the material performance of the suspension wire is not only related to the difficulty and the precision of the processing process, but also related to the performance of a final product, and therefore the material selection of the suspension wire is particularly important.
The sensor suspension wire of the conventional thromboelastography instrument on the market is generally made of stainless steel and other materials, and the materials have the defects of difficult cutting, difficult fine grinding, easy deformation and the like when being processed into the sensor suspension wire with small diameter and high precision, so that the thromboelastography instrument is insensitive to detection, poor in accuracy and the like.
Disclosure of Invention
In view of the above, the present invention provides a sensor alloy suspension wire and a thromboelastography device having the same.
According to one aspect of the invention, a sensor alloy suspension wire is provided having good elasticity, chemical resistance, fatigue resistance, and stability.
As a general preferred scheme of one embodiment of the invention, the copper content in the sensor alloy suspension wire is 60-70%, the nickel content is 5-20%, and the zinc content is 15-30%;
as a more preferable scheme of one embodiment of the invention, the copper content in the sensor alloy suspension wire is 62-68%, the nickel content is 8-15%, and the zinc content is 21-28%;
as a more preferable scheme of one embodiment of the invention, the copper content in the sensor alloy suspension wire is 62.5-67.5%, the nickel content is 8.5-12.5%, and the zinc content is 23.5-26.5%;
as a most preferable scheme of one embodiment of the invention, the copper content in the sensor alloy suspension wire is 63.5-66.5%, the nickel content is 9.0-11.0%, and the zinc content is 24.5-25.5%;
as an embodiment of the invention, the sensor alloy suspension wire has a circular groove structure in the middle, and the diameter of the metal wire in the circular groove structure is about 0.2mm, so that under the action of small viscous force, large, uniform and stable deformation can be generated, and therefore, the slight change of the viscous force can be detected more sensitively.
The sensor alloy suspension wire provided by the embodiments of the invention has excellent mechanical property and strength, and can maintain good performance in different climatic environments; the corrosion resistance is high, and the coating can withstand the corrosion of common disinfectants and volatile medicaments; the wear resistance is good, and the operation life and the performance stability in the life span of the instrument are ensured; high elasticity, and ensures the sensitivity and accuracy of monitoring the blood coagulation process; the magnetic material is non-magnetic and is not interfered by other magnetic bodies and electromagnetic fields; the processing property is easy, and the precision requirement of the sensor suspension wire is ensured.
According to another aspect of the invention, there is provided a thromboelastography device having a sensor alloy suspension wire, comprising a sensor alloy suspension wire, a detection unit, a sensor probe and a cup tray, wherein: the sensor alloy suspension wire is fixed on the upper part of the detection unit; the tail part of the sensor alloy suspension wire is fixed with the sensor probe; the sensor alloy suspension wire and the sensor probe are positioned on the central axis of the detection unit; the blood sampling cup tray is fixed on the rotary table at the bottom of the detection unit and can rotate along with the rotary table; the sensor alloy suspension wire and the sensor probe are used as stators, the blood sampling cup tray is a rotor, and in the rotation process of the blood sampling cup tray, viscous force exists between the sensor probe and a blood sample in the blood sampling cup tray, and the viscous force can cause the electric signal of the detection unit to change so as to be detected and identified. By means of the special performance of the alloy suspension wire, the sensitivity, the accuracy and the stability of the detection of the thromboelastogram instrument are ensured.
Drawings
In the drawings, the same reference numerals refer to the same or similar parts or elements throughout the several figures unless otherwise specified. The figures are not necessarily drawn to scale. These drawings depict only some embodiments in accordance with the disclosure and are not therefore to be considered to limit the scope of the disclosure.
FIG. 1 is a schematic view of a sensor alloy suspension wire according to one embodiment of the present invention;
figure 2 is a schematic diagram of a thromboelastography device having a sensor alloy suspension wire according to one embodiment of the present invention.
Detailed description of the invention
In the following, only certain exemplary embodiments are briefly described. Those skilled in the art may modify the described embodiments in a variety of different ways without departing from the spirit or scope of the present invention. Accordingly, the drawings and description are to be regarded as illustrative in nature, and not as restrictive.
As shown in fig. 1, an embodiment of the present invention provides a sensor alloy suspension wire 1, where the sensor alloy suspension wire 1 is a cu-ni-zn alloy wire with a diameter of about 0.5mm, and a circular groove structure is formed on the cu-ni-zn alloy wire, and the diameter of the circular groove structure is about 0.2mm, and the circular groove enables the sensor alloy suspension wire 1 to deform greatly under a small viscous force, so that a small change in the viscous force can be detected more sensitively.
As shown in FIG. 2, one embodiment of the present invention provides a thromboelastogram device comprising a sensor alloy suspension wire, a detection unit, a sensor probe and a blood collection cup tray;
the sensor alloy suspension wire 1 is fixed on the upper part of the detection unit 2;
the sensor probe 2 is fixed at the tail part of the sensor alloy suspension wire 1;
the sensor alloy suspension wire 1 and the sensor probe 2 are positioned on the central axis of the detection unit 2;
the blood sampling cup tray 4 is fixed on a connecting rod of the rotary table of the detection unit 2 and can rotate along with the rotary table of the detection unit 2;
the sensor alloy suspension wire 1 and the sensor probe 2 are used as stators, and the blood sampling cup tray 4 is used as a rotor;
in the rotating process of the blood collecting cup tray 4, viscosity force is generated between a blood sample in the blood collecting cup tray 4 and the sensor probe 1, the viscosity force changes along with the rotation of the blood collecting cup tray 4, and the change can cause the electric signal of the detection unit 2 to change so as to be detected and identified.

Claims (3)

1. A thromboelastography instrument comprises a sensor alloy suspension wire, wherein the sensor alloy suspension wire is made of copper-nickel-zinc alloy.
2. The sensor alloy suspension wire of claim 1, comprising 60% to 70% copper, 5% to 20% nickel, and 15% to 30% zinc.
3. The sensor alloy suspension wire of claim 1 having a circular slot configuration in the middle thereof.
CN201910442552.0A 2019-05-25 2019-05-25 Sensor alloy suspension wire and thromboelastography instrument with same Active CN111380782B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910442552.0A CN111380782B (en) 2019-05-25 2019-05-25 Sensor alloy suspension wire and thromboelastography instrument with same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910442552.0A CN111380782B (en) 2019-05-25 2019-05-25 Sensor alloy suspension wire and thromboelastography instrument with same

Publications (2)

Publication Number Publication Date
CN111380782A true CN111380782A (en) 2020-07-07
CN111380782B CN111380782B (en) 2023-07-28

Family

ID=71213355

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910442552.0A Active CN111380782B (en) 2019-05-25 2019-05-25 Sensor alloy suspension wire and thromboelastography instrument with same

Country Status (1)

Country Link
CN (1) CN111380782B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113848312A (en) * 2021-09-26 2021-12-28 恪宁科技(上海)有限公司 Suspension wire, thrombelastogram instrument with suspension wire and design method of suspension wire

Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1057497A (en) * 1996-08-20 1998-03-03 Togo Medikit Kk Puncture needle for catheter introduction
US6210312B1 (en) * 1997-05-20 2001-04-03 Advanced Cardiovascular Systems, Inc. Catheter and guide wire assembly for delivery of a radiation source
CN102286676A (en) * 2011-09-05 2011-12-21 铜陵森泰金属材料有限公司 High-strength zinc alloy
CN103335769A (en) * 2013-07-03 2013-10-02 中国科学院力学研究所 Weak force measuring device for electric thruster
CN203231843U (en) * 2013-05-08 2013-10-09 北京乐普医疗科技有限责任公司 Elastic torsion wire and micro-torsion sensor
CN203263364U (en) * 2013-03-19 2013-11-06 浙江中控研究院有限公司 Torsion detection overhanging wire and thrombelastogram instrument
CN203379185U (en) * 2013-06-04 2014-01-08 加奇生物科技(上海)有限公司 Intracranial thrombus removing device
CN104075964A (en) * 2014-07-15 2014-10-01 中国科学院苏州生物医学工程技术研究所 Viscosity and resilience detection device for blood
CN104198227A (en) * 2014-07-30 2014-12-10 北京工业大学 Catering source particulate matter and volatile organic compound sampling system
CN105441779A (en) * 2015-11-23 2016-03-30 芜湖楚江合金铜材有限公司 Firm and resilient high-performance copper alloy wire rod and preparation method thereof
CN205808994U (en) * 2016-07-20 2016-12-14 重庆鼎润医疗器械有限责任公司 Magnetic suspension thrombosis elasticity testing device
WO2017121288A1 (en) * 2016-01-11 2017-07-20 广州阳普医疗科技股份有限公司 Apparatus for measuring blood coagulation
CN107144424A (en) * 2017-06-22 2017-09-08 凌中鑫 The detection method and system of thrombelastogram instrument pendency silk stiffness factor
CN206490406U (en) * 2017-03-06 2017-09-12 朋友电力科技有限公司 Pre-hinged catenarian cable cleat
US20180172663A1 (en) * 2015-06-15 2018-06-21 Atantares Corp. A mems thrombelastograph/viscoelasticity analyzer
CN108350552A (en) * 2015-11-17 2018-07-31 威兰德-沃克公开股份有限公司 Pack fong and its application

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1057497A (en) * 1996-08-20 1998-03-03 Togo Medikit Kk Puncture needle for catheter introduction
US6210312B1 (en) * 1997-05-20 2001-04-03 Advanced Cardiovascular Systems, Inc. Catheter and guide wire assembly for delivery of a radiation source
CN102286676A (en) * 2011-09-05 2011-12-21 铜陵森泰金属材料有限公司 High-strength zinc alloy
CN203263364U (en) * 2013-03-19 2013-11-06 浙江中控研究院有限公司 Torsion detection overhanging wire and thrombelastogram instrument
CN203231843U (en) * 2013-05-08 2013-10-09 北京乐普医疗科技有限责任公司 Elastic torsion wire and micro-torsion sensor
CN203379185U (en) * 2013-06-04 2014-01-08 加奇生物科技(上海)有限公司 Intracranial thrombus removing device
CN103335769A (en) * 2013-07-03 2013-10-02 中国科学院力学研究所 Weak force measuring device for electric thruster
CN104075964A (en) * 2014-07-15 2014-10-01 中国科学院苏州生物医学工程技术研究所 Viscosity and resilience detection device for blood
CN104198227A (en) * 2014-07-30 2014-12-10 北京工业大学 Catering source particulate matter and volatile organic compound sampling system
US20180172663A1 (en) * 2015-06-15 2018-06-21 Atantares Corp. A mems thrombelastograph/viscoelasticity analyzer
CN108350552A (en) * 2015-11-17 2018-07-31 威兰德-沃克公开股份有限公司 Pack fong and its application
CN105441779A (en) * 2015-11-23 2016-03-30 芜湖楚江合金铜材有限公司 Firm and resilient high-performance copper alloy wire rod and preparation method thereof
WO2017121288A1 (en) * 2016-01-11 2017-07-20 广州阳普医疗科技股份有限公司 Apparatus for measuring blood coagulation
CN205808994U (en) * 2016-07-20 2016-12-14 重庆鼎润医疗器械有限责任公司 Magnetic suspension thrombosis elasticity testing device
CN206490406U (en) * 2017-03-06 2017-09-12 朋友电力科技有限公司 Pre-hinged catenarian cable cleat
CN107144424A (en) * 2017-06-22 2017-09-08 凌中鑫 The detection method and system of thrombelastogram instrument pendency silk stiffness factor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113848312A (en) * 2021-09-26 2021-12-28 恪宁科技(上海)有限公司 Suspension wire, thrombelastogram instrument with suspension wire and design method of suspension wire

Also Published As

Publication number Publication date
CN111380782B (en) 2023-07-28

Similar Documents

Publication Publication Date Title
US20230304849A1 (en) Apparatus for analysing the condition of a machine having a rotating part
JP5905212B2 (en) Apparatus and method for measuring prothrombin time or both prothrombin time and hematocrit by analyzing changes in reactance in specimen
CN105021519A (en) On-line atmospheric corrosion measuring device
CA2856005C (en) Device and method for determining fluid streaming potential
CN111380782A (en) Sensor alloy suspension wire and thrombelastogram instrument with same
Cai et al. Determination of Chinese Angelica honey adulterated with rice syrup by an electrochemical sensor and chemometrics
CN110500946A (en) A kind of rotary part rotation radian detection method based on three axle magnetometer
CN211426171U (en) Thrombelastogram instrument with sensor alloy suspension wire
CN103697845A (en) Method for accurately determining thickness of tobacco leaf sample
CN105388011A (en) Test apparatus for axial static rigidity of main shaft and using method thereof
CN101893544A (en) Surface wettability sensor
CN1773211A (en) Ultra-low temperature drift electric vortex vibrating/displacement sensor
Lan et al. The Influence of Blood Collection Tubes on Measurement of Cardiac Biomarkers.
CN2833506Y (en) Flange shoulder plane depth measurer
CN103760187A (en) Compressing model sample disc for dynamic thermal mechanical analyzer
CN113375545B (en) A detection method and detection device for the surface curvature of a metal material
CN211783386U (en) Novel diameter measuring probe for pipeline detector
CN201218770Y (en) Real-time monitoring device for rotation axis deflection
CN113671006A (en) Hydrogen ion selective membrane and preparation method thereof
CN202256091U (en) Piezoelectric quartz crystal sensor chip
CN208012499U (en) A kind of adjustable pressure exerting arrangement of gasket selection elasticity
CN201837327U (en) Micrometer for detecting dimension of annular inner bores
CN202956358U (en) PH detector
CN208818156U (en) A micron wire linearity detection measuring tool
CN207742142U (en) A kind of electrical resistance collection shrapnel in the online grain moisture content instrument of resistance-type

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant