CN110456093A - A kind of slide carousel, apparatus for automatically loading and pathological section scanner - Google Patents
A kind of slide carousel, apparatus for automatically loading and pathological section scanner Download PDFInfo
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- CN110456093A CN110456093A CN201910750892.XA CN201910750892A CN110456093A CN 110456093 A CN110456093 A CN 110456093A CN 201910750892 A CN201910750892 A CN 201910750892A CN 110456093 A CN110456093 A CN 110456093A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/0092—Scheduling
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
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- General Health & Medical Sciences (AREA)
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Abstract
The present invention relates to medical instruments fields, specifically further relate to a kind of slide carousel, apparatus for automatically loading and pathological section scanner.Slide carousel, including X-axis elevating mechanism, Y-axis elevating mechanism, Z-axis lifting mechanism；X-axis elevating mechanism packaged type in Z-direction connects Z axis bracket, the side of the Z axis bracket is connected with Z-axis lifting mechanism, packaged type connects scanning sensor on the Z-axis lifting mechanism, and the upper surface of the scanning sensor is connected with one group of Y-axis elevating mechanism.Using glass slide apparatus for automatically loading of the invention, it can be achieved that a vast capacity loads, it is not necessarily to the frequent loading and unloading of operator and complete monitoring, the time is saved and improves scan efficiency；Transmission device of the invention can realize while pick and place, and improve clamping efficiency, reduce the waiting time between piece and piece, while the setting control of chucking power can be done in effective travel, and can monitor that whether there is or not clip to glass slide and prevent from clipping broken glass slide energy-efficient.
Description
Technical field
The present invention relates to medical instruments fields, specifically further relate to a kind of slide carousel, apparatus for automatically loading and
Pathological section scanner.
Background technique
Pathologic finding is the Pathomorphology method for the pathological change being used to check in biological organs, tissue or cell.For
Inquire into organ, the lysis that tissue or cell are occurred, the method that certain Pathomorphology inspection can be used checks their institutes
The lesion of generation inquires into lesion Producing reason, pathogenesis, the occurrence and development process of lesion, finally makes pathological diagnosis.Disease
Morphologic inspection method is managed, the pathological change of gross specimen is looked first at, then cuts a certain size pathological tissues, with disease
Pathological section is made in reason Histological method, further checks lesion with microscope.
In view of when carrying out slice scanner, the objective table of micro optical system needs certain free travel, institute
It is arranged at the side of optical microscope system with slice handling system in the prior art, avoids interfering loading when being sliced scanning
The movement of platform；And when being sliced handling, slice handling system is moved to apart from the closer position of objective table load station or loading
Platform moves to its free travel dimension close to the endpoint of slice handling system side, and transport mechanism is mostly purely mechanic dress
It sets, position is inaccurate for transmission, speed is slow, the problems such as piece, card, fragmentation are easy to appear in transmit process.Secondly, the prior art
In pathological section scanner its be sliced handling system maximum capacity be 400, it is a piece of slice handling plus scanning time be
Be within 1.2 minutes it is cracking, then continuous scans through of 400 slices almost needs 8 hours, this is also pathologist
The daily work hours.In practical operation, in order to improve recall ratio and pertinency factor, each tissue sample of patient needs to be made into ten
Several or even tens slices, the slice that daily ten a few to tens of tissue samples are made into may just reach 400, some big
Hospital or special tumour hospital, this slice capacity are still unable to meet demand.
Summary of the invention
In order to solve the above technical problems, the first aspect of the invention provides a kind of slide carousel, packet
Include X-axis elevating mechanism, Y-axis elevating mechanism, Z-axis lifting mechanism；X-axis elevating mechanism packaged type in Z-direction connects Z
Bracing strut, the side of the Z axis bracket are connected with Z-axis lifting mechanism, and packaged type connection scanning passes on the Z-axis lifting mechanism
Sensor, the upper surface of the scanning sensor are connected with one group of Y-axis elevating mechanism.
As a kind of perferred technical scheme, one group of electronic Qu Pian mechanism is connected between one group of Y-axis elevating mechanism.
As a kind of perferred technical scheme, the bottom of the Z axis bracket is connected with the mobile wire casing of X-axis, and the X-axis is mobile
Wire casing can move that Z axis bracket is driven to be moved on X-axis elevating mechanism；Z axis shifting is connected at the top of the Z axis bracket
Moving-wire slot, the mobile wire casing of the Z axis can move that scanning sensor is driven to be moved on Z-axis lifting mechanism.
As a kind of perferred technical scheme, there are two one group of Y-axis elevating mechanisms, two Y-axis elevating mechanisms are side by side
Connection；There are two one group of electronic Qu Pian mechanisms, and two electronic Qu Pian mechanisms connect side by side；Described two Y-axis elevating mechanisms
Controlling two electronic Qu Pian mechanisms respectively can be moved in the Y-axis direction.
As a kind of perferred technical scheme, one end of the X-axis elevating mechanism and Z-axis lifting mechanism is respectively connected with electricity
Machine.
As a kind of perferred technical scheme, described two motors can control the mobile wire casing of X-axis and the mobile wire casing of Z axis respectively
It is mobile, so that control device can arbitrarily move in X-axis, Z-direction.
The second aspect of the invention provides a kind of glass slide apparatus for automatically loading, transmits dress including above-mentioned glass slide
It sets, the slide carousel can arbitrarily move in X-axis, Y-axis, Z-direction.
It as a kind of perferred technical scheme, further include slice box device, the slice box device is for holding slice；Institute
The slice to be scanned removal being sliced in box device can be scanned by stating slide carousel, again by scanned slice
It moves into slice box device.
As a preferred embodiment, the slice box device and slide carousel are mutually indepedent.
As a kind of perferred technical scheme, the slice box device uses multi-layer structure design, wherein the slice box
Four rows × 10 column slice box card slots are equipped in device altogether, 40 slice boxes can be at most placed, can at most be placed in each slice box
25 slices.
As a kind of perferred technical scheme, the slice box is placed in slice box device and can be detected, and uses
Traffic light system, green indicate to complete, and blue indicates ready, and red indicates abnormal.
The third aspect of the invention provides a kind of pathological section scanner, including above-mentioned glass slide loads automatically
It sets.
Compared with prior art, the invention has the following beneficial effects:
The present invention provides a kind of novel pathological section scanners can using glass slide apparatus for automatically loading of the invention
It realizes that a vast capacity loads, is not necessarily to the frequent loading and unloading of operator and complete monitoring, save the time and improve scan efficiency；Together
When transmission device of the invention of arranging in pairs or groups can realize while pick and place, improve clamping efficiency, reduce the waiting time between piece and piece, together
When the setting control of chucking power can be done in effective travel, and can monitor whether there is or not clipping to glass slide and prevent from clipping broken glass slide, also
It can accurately judge that each film magazine loads glass slide quantity, and be confirmed whether that the states such as lamination, oblique plug-in card occur, it is energy-efficient.
Detailed description of the invention
Illustrate technical solution of the present invention in order to clearer, attached drawing used in embodiment will be done simply below
It introduces, drawings discussed below is only some embodiments of the present invention, and those skilled in the art are said, is not paying creation
Property labour under the premise of, be also possible to obtain other drawings based on these drawings.
Fig. 1 is the perspective view of the slide carousel of embodiment 1；
Fig. 2 is the front view of the slide carousel of embodiment 1；
Fig. 3 is the right view of the slide carousel of embodiment 1；
Fig. 4 is the glass slide apparatus for automatically loading schematic diagram of embodiment 2；
Fig. 5 is the pathological section scanner schematic diagram of embodiment 3；
Number in figure is successively are as follows:
1, scanning sensor；2, Z-axis lifting mechanism；3, Y-axis elevating mechanism；4, X-axis elevating mechanism；5, electronic to take piece machine
Structure；6, Z axis bracket；7, motor；The mobile wire casing of 8-1, X-axis；The mobile wire casing of 8-2, Z axis；9, it is sliced box；10, it is sliced；11, image
Platform；12, camera.
Specific embodiment
The technical characteristic in present invention offer technical solution is done With reference to embodiment further clear, complete
Description.
The first aspect of the invention provides a kind of slide carousel, including X-axis elevating mechanism 4, Y-axis elevator
Structure 3, Z-axis lifting mechanism 2；The X-axis elevating mechanism 4 packaged type in Z-direction connects Z axis bracket 6, the Z axis bracket 6
Side be connected with Z-axis lifting mechanism 2, packaged type connects scanning sensor 1, scanning biography on the Z-axis lifting mechanism 2
The upper surface of sensor 1 is connected with one group of Y-axis elevating mechanism 3.
In a preferred embodiment, one group of electronic Qu Pian mechanism is connected between one group of Y-axis elevating mechanism 3
5。
In a preferred embodiment, the bottom of the Z axis bracket 6 is connected with the mobile wire casing 8-1 of X-axis, the X-axis
Mobile wire casing 8-1 can move that Z axis bracket 6 is driven to be moved on X-axis elevating mechanism 4；The top of the Z axis bracket 6
It is connected with the mobile wire casing 8-2 of Z axis, the mobile wire casing 8-2 of the Z axis can move that scanning is driven to sense on Z-axis lifting mechanism 2
Device 1 is moved.
In a preferred embodiment, there are two one group of Y-axis elevating mechanisms 3, two Y-axis elevating mechanisms 3 are simultaneously
Row's connection；There are two one group of electronic Qu Pian mechanisms 5, and two electronic Qu Pian mechanisms 5 connect side by side；Described two Y-axis liftings
Mechanism 3 controls two electronic Qu Pian mechanisms 5 respectively and can be moved in the Y-axis direction.
In a preferred embodiment, one end of the X-axis elevating mechanism 4 and Z-axis lifting mechanism 2 is respectively connected with electricity
Machine 7.
In a preferred embodiment, described two motors 7 can control the mobile wire casing 8-1 of X-axis respectively and Z axis is mobile
Wire casing 8-2 is mobile, so that control device can arbitrarily move in X-axis, Z-direction.
Slide carousel of the present invention allows rotary extension mobile by above structure, translation etc., accurate fixed
Certain point of the position into space carries out operation, and using two motors 7, control device is displaced to X-axis, Z axis respectively, and is passed through
Two Y-axis elevating mechanisms 3 control two electronic Qu Pian mechanisms 5 respectively while carry out slice 10 is removed and placed into operation, and lead to
The quantity of slice 10 in the monitoring judgement slice box 9 of sensor 1 is over-scanned, and is confirmed whether there are the states such as lamination, oblique plug-in card,
Traffic light system is transmitted information back to and used simultaneously, and green indicates to complete, and blue expression is ready, and red indicates abnormal.
The second aspect of the invention provides a kind of glass slide apparatus for automatically loading, transmits dress including above-mentioned glass slide
It sets, the slide carousel can arbitrarily move in X-axis, Y-axis, Z-direction.
It in a preferred embodiment, further include slice box device, the slice box device is for holding slice 10；
The removal of slice to be scanned 10 being sliced in box device can be scanned by the slide carousel, by scanned slice
10 move into again in slice box device.
In a preferred embodiment, the slice box device and slide carousel are mutually indepedent.
It is controlled in two 5 pairs of slice box devices of electronic Qu Pian mechanism arranged side by side in the present invention by slide carousel
Slice 10 carries out loading or unloading operation, while an electronic Qu Pian mechanism 5 takes out slice 10 wherein, another electronic Qu Pian mechanism
5 reappose scanned slice 10 in former slice 9 position of box, and are sliced in box device and at most carry 1000
Slice, more convenient than traditional single loading or unloading operation, carrying is more, more saving the time improves efficiency.
In a preferred embodiment, the slice box device uses multi-layer structure design, wherein the slice box
Four rows × 10 column slice box card slots are equipped in device altogether, 40 slice boxes 9 can be at most placed, can at most be put in each slice box 9
Set 25 slices 10.
In a preferred embodiment, the slice box 9 is placed in slice box device and can be detected, and uses
Traffic light system, green indicate to complete, and blue indicates ready, and red indicates abnormal.
The third aspect of the invention provides a kind of pathological section scanner, including above-mentioned glass slide loads automatically
It sets.
It in a preferred embodiment, further include camera 12 and image platform 11；The glass slide loads automatically
Set, camera 12, image platform 11 it is mutually indepedent；
Pathological section scanner of the present invention is by using above-mentioned glass slide apparatus for automatically loading, from slice box device
It takes out slice 10 and scanning of taking pictures is carried out by camera 12, browsed using 11 pairs of slices of image platform, analyze and reach to pathology
The judgement of form.
The present invention is specifically described below by embodiment, following embodiment is only used for the present invention and does further
Illustrate, can not be interpreted as the limitation that the present invention protects, professional and technical personnel in the field makes according to the content of foregoing invention
Nonessential correction and adjustment, still fall within the range of protection of the invention.
Embodiment 1
A kind of slide carousel, as shown in Figure 1, Figure 2, Figure 3 shows, including X-axis elevating mechanism 4, Y-axis elevating mechanism 3, Z
Axis elevating mechanism 2；The X-axis elevating mechanism 4 packaged type connection Z axis bracket 6 in Z-direction, the one of the Z axis bracket 6
Side is connected with Z-axis lifting mechanism 2, and packaged type connects scanning sensor 1, the scanning sensor on the Z-axis lifting mechanism 2
1 upper surface is connected with one group of Y-axis elevating mechanism 3；
One group of electronic Qu Pian mechanism 5 is connected between one group of Y-axis elevating mechanism 3；
The bottom of the Z axis bracket 6 is connected with the mobile wire casing 8-1 of X-axis, and the mobile wire casing 8-1 of the X-axis can be gone up and down in X-axis
It is mobile to drive Z axis bracket 6 to be moved in mechanism 4；The top of the Z axis bracket 6 is connected with the mobile wire casing 8-2 of Z axis, institute
Stating the mobile wire casing 8-2 of Z axis can move that scanning sensor 1 is driven to be moved on Z-axis lifting mechanism 2；
There are two one group of Y-axis elevating mechanisms 3, and two Y-axis elevating mechanisms 3 connect side by side；Described one group electronic to take piece
There are two mechanisms 5, and two electronic Qu Pian mechanisms 5 connect side by side；Described two Y-axis elevating mechanisms 3 control two respectively and electronic take
Piece mechanism 5 can be moved in the Y-axis direction；
One end of the X-axis elevating mechanism 4 and Z-axis lifting mechanism 2 is respectively connected with motor 7, and described two motors 7 can be distinguished
It is mobile to control X-axis mobile wire casing 8-1 and the mobile wire casing 8-2 of Z axis, so that control device can arbitrarily move in X-axis, Z-direction.
The slide carousel allows rotary extension mobile by above structure, and translation etc. is pin-pointed to sky
Between in certain point carry out operation, using two motors 7, control device is displaced to X-axis, Z axis respectively, and passes through two Y-axis
Elevating mechanism 3 controls two electronic Qu Pian mechanisms 5 respectively while carrying out the operation that is removed and placed into of slice 10, and is passed by scanning
The quantity of slice 10 in the monitoring judgement slice box 9 of sensor 1, and it is confirmed whether there are the states such as lamination, oblique plug-in card, while will letter
Breath is passed back and using traffic light system, and green indicates to complete, and blue indicates ready, and red indicates abnormal.
Embodiment 2
A kind of glass slide apparatus for automatically loading, as shown in figure 4, including the slide carousel of embodiment 1, the load glass
Piece transmission device can arbitrarily move in X-axis, Y-axis, Z-direction.
It further include slice box device, the slice box device is for holding slice 10；The slide carousel can incite somebody to action
The removal of slice to be scanned 10 in slice box device is scanned, and scanned slice 10 is moved into slice box device again
In；The slice box device and slide carousel are mutually indepedent；
The slice box device uses multi-layer structure design, wherein is equipped with four rows × 10 column in the slice box device altogether
It is sliced box card slot, 40 slice boxes can be at most placed, can at most place 25 slices in each slice box；
The slice box 9 is placed in slice box device and can be detected, and uses traffic light system, and green has indicated
At blue indicates ready, and red indicates abnormal.
Two electronic Qu Pian mechanisms 5 arranged side by side are controlled by slide carousel in the glass slide apparatus for automatically loading
Loading or unloading operation is carried out to the slice 10 in slice box device, while an electronic Qu Pian mechanism 5 takes out slice 10 wherein, separately
One electronic Qu Pian mechanism 5 reapposes scanned slice 10 in former slice 9 position of box, and is sliced box device
In at most carry 1000 slices, it is more convenient than traditional single loading or unloading operation, carrying is more, more save the time and improve effect
Rate.
Embodiment 3
A kind of pathological section scanner, as shown in figure 5, including glass slide apparatus for automatically loading as described in example 2；Also wrap
Include camera 12 and image platform 11；The glass slide apparatus for automatically loading, camera 12, image platform 11 are mutually indepedent；
The pathological section scanner takes out slice from slice box 9 by using above-mentioned glass slide apparatus for automatically loading
10 carry out scanning of taking pictures by camera 12, are browsed using image platform 11 to slice, analyze to reach and sentence to pathomorphism
It is disconnected.
Claims (10)
1. a kind of slide carousel, which is characterized in that including X-axis elevating mechanism, Y-axis elevating mechanism, Z-axis lifting mechanism；
X-axis elevating mechanism packaged type in Z-direction connects Z axis bracket, and the side of the Z axis bracket is connected with Z axis lifting
Mechanism, packaged type connects scanning sensor on the Z-axis lifting mechanism, and the upper surface of the scanning sensor is connected with one group
Y-axis elevating mechanism.
2. slide carousel as described in claim 1, which is characterized in that connected between one group of Y-axis elevating mechanism
There is one group of electronic Qu Pian mechanism.
3. slide carousel as claimed in claim 1 or 2, which is characterized in that the bottom of the Z axis bracket is connected with X
Axis moves wire casing, and the mobile wire casing of the X-axis can move that Z axis bracket is driven to be moved on X-axis elevating mechanism；The Z
The mobile wire casing of Z axis is connected at the top of bracing strut, the mobile wire casing of the Z axis can move to drive and sweep on Z-axis lifting mechanism
Sensor is retouched to be moved.
4. slide carousel as claimed in claim 3, which is characterized in that there are two one group of Y-axis elevating mechanisms, and two
A Y-axis elevating mechanism connects side by side；There are two one group of electronic Qu Pian mechanisms, and two electronic Qu Pian mechanisms connect side by side；Institute
Stating two Y-axis elevating mechanisms and controlling two electronic Qu Pian mechanisms respectively to be moved in the Y-axis direction.
5. slide carousel as claimed in claim 1 or 2, which is characterized in that the X-axis elevating mechanism and Z axis lifting
One end of mechanism is respectively connected with motor.
6. a kind of glass slide apparatus for automatically loading, which is characterized in that passed including glass slide of any of claims 1-5
Device is sent, the slide carousel can arbitrarily move in X-axis, Y-axis, Z-direction.
7. glass slide apparatus for automatically loading as claimed in claim 6, which is characterized in that it further include slice box device, it is described to cut
Piece box device is for holding slice；The slide carousel can sweep the slice to be scanned removal being sliced in box device
It retouches, scanned slice is moved into again in slice box device.
8. glass slide apparatus for automatically loading as claimed in claim 7, which is characterized in that the slice box device uses multilayer knot
Structure design, wherein four rows × 10 column slice box card slots are equipped in the slice box device altogether, can at most place 40 slice boxes,
25 slices can be at most placed in each slice box.
9. glass slide apparatus for automatically loading as claimed in claim 7, which is characterized in that it is box-packed that the slice box is placed in slice
It can be detected in setting, and use traffic light system, green indicates to complete, and blue indicates ready, and red indicates abnormal.
10. a kind of pathological section scanner, which is characterized in that filled automatically including glass slide as claim in any one of claims 6-9
It carries and sets.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910750892.XA CN110456093A (en) | 2019-08-14 | 2019-08-14 | A kind of slide carousel, apparatus for automatically loading and pathological section scanner |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910750892.XA CN110456093A (en) | 2019-08-14 | 2019-08-14 | A kind of slide carousel, apparatus for automatically loading and pathological section scanner |
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Cited By (5)
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| CN110926852A (en) * | 2019-11-18 | 2020-03-27 | 迪普派斯医疗科技(山东)有限公司 | Automatic film changing system and method for digital pathological section |
| CN113189099A (en) * | 2021-04-16 | 2021-07-30 | 杭州医派智能科技有限公司 | Pathological section scanner |
| CN113968408A (en) * | 2021-10-09 | 2022-01-25 | 中国人民解放军海军第九〇五医院 | Automated inspection specimen and/or pathological section transportation and storage system |
| CN115744253A (en) * | 2022-11-17 | 2023-03-07 | 深圳市锦瑞生物科技股份有限公司 | Grabbing device and equipment |
| CN117890183A (en) * | 2024-03-14 | 2024-04-16 | 济南中仁谊科医学检验实验室有限公司 | Paraffin section processing device |
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| CN117890183A (en) * | 2024-03-14 | 2024-04-16 | 济南中仁谊科医学检验实验室有限公司 | Paraffin section processing device |
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Application publication date: 20191115 |