CN110200283A - A kind of curcumin composite particles electuary with anti-oxidation function - Google Patents
A kind of curcumin composite particles electuary with anti-oxidation function Download PDFInfo
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- CN110200283A CN110200283A CN201910612195.8A CN201910612195A CN110200283A CN 110200283 A CN110200283 A CN 110200283A CN 201910612195 A CN201910612195 A CN 201910612195A CN 110200283 A CN110200283 A CN 110200283A
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- extracting solution
- curcumin
- blueberry
- concentrate
- composite particles
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention belongs to field of health care food, are a kind of curcumin composite particles electuaries and preparation method thereof with anti-oxidation function.The composite particles electuary is through raw material screening, pick out the preparation that the raw material extracting solution with antioxidant activity carries out compound electuary, final curcumin extracting solution, Cordyceps militaris extracting solution, blueberry extracting solution, jujube extract, fructus lycii extracted solution, green tea extractive liquor, ethylmaltol, carboxymethyl cellulose sodium, citric acid, the xylitol chosen is deployed according to a certain percentage, using the manufactured composite particles electuary with anti-oxidation function after the processing of 3 D stereo granulating technique.The features such as composite particles electuary not only has a good anti-oxidation efficacy, and nutritive value also with higher, taste are sour-sweet moderate, easy to maintain, and aspect carries, brews rear bright color, solution stable homogeneous, no precipitating.
Description
Technical field
The present invention relates to technical field of health care food more particularly to a kind of curcumin composite particles with anti-oxidation function
The preparation method of electuary.
Background technique
With the development of the times, people enhance itself health care consciousness year by year.Research has shown that some external environments and
Factor can accelerate the generation of people's interior free yl, so as to cause a series of related disease.Vehicle exhaust, industrial exhaust gas
While leading to environmental pollution, but also the free radical of our human bodies increases.The use of the high-tech products such as mobile phone, computer, makes
We enjoy the convenience of science and technology on one side, and the moment is in a large amount of radiation when one side, these rays can accelerate the oxygen of cell
Change.In addition, some inappropriate life styles can also induce body to generate more free radicals, such as smoke, excessive drinking, stress
Excessive, grease intake is excessively.The increase of free radical can accelerate the aging of human body, so that body the feature of aging is occurred, such as skin
There is spot and wrinkle etc., on the other hand can also cause the degenerative diseases such as cardiovascular and cerebrovascular, hypertension.However, some anti-oxidant
Drug have many side effects, so extracted from natural products have oxidation resistant bioactive ingredients just become outstanding
It is important.
Curcumin is a kind of polyphenol separated from the rhizome of turmeric, with extensive bioactivity, such as antioxygen
Change, anticancer, anti-inflammatory and anti-diabetic activity.Through practical proof, curcumin has stronger free radical scavenging ability and anti-oxidant
Effect, is a kind of good Natural Antioxidants.However, curcumin property is unstable, light-exposed easy decomposition, therefore make
A curcumin particle electuary with anti-oxidation function can decompose caused by storing in transit to avoid curcumin, make it
Activity reduce, in addition, particle electuary have the advantages that it is easy to maintain, be convenient for carrying and can solve the above problems very well.
Summary of the invention
The curcumin composite particles electuary and its preparation side that the purpose of the present invention is to provide a kind of with anti-oxidation function
Method, to solve the problems mentioned in the above background technology.
The present invention is achieved through the following technical solutions:
Through raw material screening, the preparation that the raw material extracting solution with antioxidant activity carries out compound electuary is picked out, chooses curcumin
Extracting solution, Cordyceps militaris extracting solution, blueberry extracting solution, jujube extract, fructus lycii extracted solution, green tea extractive liquor, ethylmaltol, carboxylic
Methyl cellulose sodium, citric acid, xylitol manufactured anti-oxidant composite particles electuary after processing according to a certain percentage.
To achieve the above object, a kind of preparation method of anti-oxidant instant, at least includes the following steps
(1) fresh turmeric rhizome cleaned, be sliced, dried, crushed, it is spare to obtain curcuma powder for 40 meshes excessively.
(2) Cordyceps militaris, blueberry, jujube, fructus lycii, green tea are cleaned, crushed 40 meshes, it is spare.
(3) curcumin in turmeric, the anthocyanidin in blueberry are extracted using ultrasonic wave secondary solvent extraction, is mentioned
It is 1:10 ~ 1:20 that take condition, which be solid-liquid ratio, and concentration of alcohol is 70% ~ 90%, and ultrasonic time is 30min ~ 45min, ultrasonic function
Rate is 350w ~ 500w.
(4) Cordyceps militaris, jujube, polysaccharides, green tea polyphenols are extracted using water extraction, extraction conditions are solid-liquid ratio
1:15 ~ 1:20, Extracting temperature are 80 ~ 100 DEG C, 30 ~ 60min of extraction time.
(5) step (3), (4) are filtered obtained extracting solution and is carried out being concentrated into the 1/ of original volume respectively with Rotary Evaporators
10 ~ 1/12 is spare.
(6) the resulting concentrate curcumin of step (5) is extracted into concentrate 10% ~ 20%, Cordyceps militaris extract concentrate 10 ~
20%, blueberry extracts concentrate 5% ~ 15%, jujube concentrated extracting solution 5% ~ 10%, fructus lycii concentrated extracting solution 3% ~ 8%, green tea and is concentrated and mentions
It takes liquid 5% ~ 15% to be mixed, 0.5% ~ 1.0% citric acid, 0.1% ~ 0.2% carboxymethyl cellulose sodium, 0.15% ~ 0.2% sugarcane is then added
Sugar fatty acid ester, 0.001% ~ 0.002% ethylmaltol, 20% ~ 40% xylitol, be uniformly mixed.
(7) particle obtained by step (6) is dried, oven temperature is 60 DEG C ~ 70 DEG C, crosses 20 ~ 40 meshes.
The curcumin composite particles electuary of obtained anti-oxidation function, is claimed by the weight percent of composition of raw materials
Take each component, it is formulated, mix, be granulated, being drying to obtain.
These raw materials that the present invention chooses can serve oxidation resistant, and specific effect is as follows:
(1) turmeric: a kind of natural plants of the turmeric as integration of drinking and medicinal herbs, primary bioactive components are curcumin and volatilization
Oil.The effects of curcumin main antioxidant, reducing blood lipid, cholagogue, anticancer.Curcumin can directly remove free radical in vivo and in vitro
(ROS and RNS) and hydrogen peroxide.Compared with other polyphenol compounds (resveratrol and Quercetin), find curcumin clear
In terms of except ROS faster.
(2) Cordyceps militaris: also known as northern Chinese caterpillar Fungus, representative 4 kinds of main pharmacological components: cordycepin, cordycepic acid, cordyceps sinensis
Polysaccharide and SOD enzyme.And the medical value of the various bioactivators such as Cordyceps sinensis polysaccharide and SOD is the most significant.Cordyceps sinensis polysaccharide is one
The highly branched galactomannans of kind, it can promote the immune function of lymphocyte transformation and body, and enhancing body itself is anti-
The ability of cancer suppression cancer.SOD(superoxide dismutase) superoxide radical in body can be eliminated, there is anti-aging, anticancer to press down cancer
Effect.
(3) blueberry: blueberry contains extremely abundant flavonoids and polysaccharide compound, thus be otherwise known as " berry it
King ".Nutritional ingredient rich in Blueberry, having prevents cranial nerve aging, protection eyesight, heart tonifying, anticancer, softening blood
The functions such as manage, enhance the immune of the body.Wherein, since blueberry is rich in anthocyanidin, have effects that activate retina, view can be strengthened
Power prevents eyeball fatigue and is gazed at.It is also one of the five big healthy fruit that the World Food Programme is recommended.Blueberry is in addition to containing
Its main function of superoxide dismutase (SOD) also rich in is exclusively to remove biological oxidation outside anthocyanidin abundant
The ultra-oxygen anion free radical of middle generation is known as " the health care gold of 21 century ".
(4) jujube: also known as " jujube " its rich in protein, fat, carbohydrate, carrotene, B family vitamin, vitamin C,
The nutritional ingredients such as citrin and calcium, phosphorus, iron and cyclic adenosine monophosphate.Wherein ascorbic content comes out at the top in fruit,
Vitamin C contained in jujube is a kind of highly active reproducibility antioxidant, participates in intracorporal physiology oxygen reduction mistake
Journey prevents melanin chronic precipitating in vivo, can efficiently reduce the generation of pigment senile plaque.
(5) fructus lycii: fructus lycii contains carbohydrate, amino acid, microelement, a variety of nutrition such as alkaloids and inorganic salts at
Point.Polysaccharides can also prevent glycosuria urine disease from causing to all having antioxidant activity in the multiple organs of whole body by anti-oxidant
Renal dysfunction, furthermore it can also can act as oxidation resistant effect to muscle, pancreas, heart and Skin Cell.It is total yellow
Ketone is another kind of main oxidation-resistant active ingredient in fructus lycii, it, which can effectively remove super feeding ion and hydroxyl free radical, reduces rouge
Class molecule peroxidating.To sum up, fructus lycii can pass through the activity and water of removing various active oxygen radical, the anti-oxidant albumen of raising
It puts down, reduce the generation of biomolecule oxide to play oxidation resistant effect.
(6) green tea: tea polyphenols rich in, caffeine, lipopolysaccharides, theanine in green tea.Help to delay senescence, tea
Polyphenol has very strong inoxidizability and physiological activity, is the scavenger of human free radical.Research has shown that 1 milligram of tea polyphenols is removed
9 microgram superoxide dismutases are equivalent to the efficiency of the harmful excessive free radicals of people's human body, are much higher than other allied substances.
Tea polyphenols have blocking peroxidatic reaction of lipid, the effect of scavenging capacity enzyme.Through research confirm tea polyphenols antioxidant effect than
Vitamin E is 18 times strong.
Of the invention uses based on curcumin extracting solution, cordyceps sinensis extracting solution, blueberry extracting solution, jujube extract, fructus lycii
Supplemented by extracting solution, green tea extractive liquor, using electuary made from 3 D stereo granulating technique, which not only has good
The features such as good anti-oxidation efficacy, nutritive value also with higher, taste are sour-sweet moderate, easy to maintain, aspect carrying, after brewing
Bright color, solution stable homogeneous, no precipitating.
Specific embodiment
Further description of the technical solution of the present invention below, and however, it is not limited to this, and counter is to the technology of the present invention
Scheme is modified or is replaced on an equal basis, without departing from the spirit and scope of inventive technique scheme, should all cover of the invention
In protection scope.
Embodiment 1
This implementation provides a kind of curcumin composite particles electuary with anti-oxidation function, and procedure of processing is as follows:
(1) fresh turmeric rhizome cleaned, be sliced, dried, crushed, it is spare to obtain curcuma powder for 40 meshes excessively.
(2) Cordyceps militaris, blueberry, jujube, fructus lycii, green tea are cleaned, crushed 40 meshes, it is spare.
(3) curcumin in turmeric, the anthocyanidin in blueberry are extracted using ultrasonic wave secondary solvent extraction, is mentioned
It is 1:20 that take condition, which be solid-liquid ratio, concentration of alcohol 85%, ultrasonic time 40min, and 60 DEG C of ultrasonic temperature, ultrasonic power is
400w。
(4) Cordyceps militaris, jujube, polysaccharides, green tea polyphenols are extracted using water extraction, extraction conditions are solid-liquid ratio
1:15, Extracting temperature are 90 DEG C, extraction time 20min.
(5) step (3), (4) are filtered obtained extracting solution and is carried out being concentrated into the 1/ of original volume respectively with Rotary Evaporators
10 is spare.
(6) the resulting concentrate curcumin of step (5) is extracted into concentrate 15%, Cordyceps militaris extracts concentrate 15%, blueberry
It extracts concentrate 8%, jujube concentrated extracting solution 5%, fructus lycii concentrated extracting solution 3%, green tea concentrated extracting solution 10% to be mixed, then
Be added 0.5% citric acid, 0.15% carboxymethyl cellulose sodium, 0.15% sucrose fatty ester, 0.001% ethylmaltol, 40% wood
Sugar alcohol is uniformly mixed.
(7) particle obtained by step (6) is dried, oven temperature is 60 DEG C, crosses 20 meshes.
(8) every 10g is that a packet is packaged.
(9) 50mL can be used when eating, 60 DEG C of water is brewed.
Embodiment 2
This implementation provides a kind of curcumin composite particles electuary with anti-oxidation function, and procedure of processing is as follows:
(1) fresh turmeric rhizome cleaned, be sliced, dried, crushed, it is spare to obtain curcuma powder for 40 meshes excessively.
(2) Cordyceps militaris, blueberry, jujube, fructus lycii, green tea are cleaned, crushed 40 meshes, it is spare.
(3) curcumin in turmeric, the anthocyanidin in blueberry are extracted using ultrasonic wave secondary solvent extraction, is mentioned
It is 1:15, concentration of alcohol 80%, ultrasonic time 30min, ultrasonic power 400w that take condition, which be solid-liquid ratio,.
(4) Cordyceps militaris, jujube, polysaccharides, green tea polyphenols are extracted using water extraction, extraction conditions are solid-liquid ratio
1:15, Extracting temperature are 90 DEG C, extraction time 20min.
(5) step (3), (4) are filtered obtained extracting solution and is carried out being concentrated into the 1/ of original volume respectively with Rotary Evaporators
12 is spare.
(6) the resulting concentrate curcumin of step (5) is extracted into concentrate 20%, Cordyceps militaris extracts concentrate 20%, blueberry
It extracts concentrate 5%, jujube concentrated extracting solution 5%, fructus lycii concentrated extracting solution 3%, green tea concentrated extracting solution 5% to be mixed, then
Be added 0.5% citric acid, 0.12% carboxymethyl cellulose sodium, 0.20% sucrose fatty ester, 0.001% ethylmaltol, 40% wood
Sugar alcohol is uniformly mixed.
(7) particle obtained by step (6) is dried, oven temperature is 60 DEG C, crosses 20 meshes.
(8) every 10g is that a packet is packaged.
(9) 50mL can be used when eating, 60 DEG C of water is brewed.
Claims (3)
1. a kind of curcumin composite particles electuary with anti-oxidation function, according to the optimization formula of mass percent are as follows: turmeric
Element extracts concentrate 10% ~ 20%, Cordyceps militaris extracts concentrate 10 ~ 20%, blueberry extracts concentrate 5% ~ 15%, jujube concentration extraction
Liquid 5% ~ 10%, fructus lycii concentrated extracting solution 3% ~ 8%, green tea concentrated extracting solution 5% ~ 15% are mixed, and 0.5% ~ 1.0% lemon is then added
Lemon acid, 0.1% ~ 0.2% carboxymethyl cellulose sodium, 0.15% ~ 0.2% sucrose fatty ester, 0.001% ~ 0.002% ethylmaltol, 20%
~ 40% xylitol is uniformly mixed, is then granulated, is drying to obtain.
2. requiring a kind of curcumin composite particles electuary with anti-oxidation function according to right 1, procedure of processing is such as
Under:
(1) fresh turmeric rhizome cleaned, be sliced, dried, crushed, crossing 40 meshes, to obtain curcuma powder spare,
(2) Cordyceps militaris, blueberry, jujube, fructus lycii, green tea are cleaned, crushed 40 meshes, it is spare,
(3) curcumin in turmeric, the anthocyanidin in blueberry are extracted using ultrasonic wave secondary solvent extraction, extracts item
It is 1:20 that part, which is solid-liquid ratio, concentration of alcohol 85%, ultrasonic time 40min, 60 DEG C of ultrasonic temperature, ultrasonic power 400w,
(4) Cordyceps militaris, jujube, polysaccharides, green tea polyphenols are extracted using water extraction, extraction conditions are solid-liquid ratio 1:
15, Extracting temperature is 90 DEG C, extraction time 20min,
(5) by step (3), (4) filter obtained extracting solution respectively with Rotary Evaporators be concentrated into original volume it is 1/10 standby
With,
(6) the resulting concentrate curcumin of step (5) is extracted into concentrate 15%, Cordyceps militaris extracts concentrate 15%, blueberry extracts
Concentrate 8%, jujube concentrated extracting solution 5%, fructus lycii concentrated extracting solution 3%, green tea concentrated extracting solution 10% are mixed, and are then added
0.5% citric acid, 0.15% carboxymethyl cellulose sodium, 0.15% sucrose fatty ester, 0.001% ethylmaltol, 40% xylose
Alcohol is uniformly mixed, and sieving is granulated,
(7) particle obtained by step (6) being dried, oven temperature is 60 DEG C, 20 meshes are crossed,
(8) every 10g is that a packet is packaged,
(9) 50mL can be used when eating, 60 DEG C of water is brewed.
3. requiring a kind of curcumin composite particles electuary with anti-oxidation function according to right 1, procedure of processing is such as
Under:
(1) fresh turmeric rhizome cleaned, be sliced, dried, crushed, crossing 40 meshes, to obtain curcuma powder spare,
(2) Cordyceps militaris, blueberry, jujube, fructus lycii, green tea are cleaned, crushed 40 meshes, it is spare,
(3) curcumin in turmeric, the anthocyanidin in blueberry are extracted using ultrasonic wave secondary solvent extraction, extracts item
It is 1:15 that part, which is solid-liquid ratio, concentration of alcohol 80%, ultrasonic time 30min, ultrasonic power 400w,
(4) Cordyceps militaris, jujube, polysaccharides, green tea polyphenols are extracted using water extraction, extraction conditions are solid-liquid ratio 1:
15, Extracting temperature is 90 DEG C, extraction time 20min,
(5) by step (3), (4) filter obtained extracting solution respectively with Rotary Evaporators be concentrated into original volume it is 1/12 standby
With,
(6) the resulting concentrate curcumin of step (5) is extracted into concentrate 20%, Cordyceps militaris extracts concentrate 20%, blueberry extracts
Concentrate 5%, jujube concentrated extracting solution 5%, fructus lycii concentrated extracting solution 3%, green tea concentrated extracting solution 5% are mixed, and are then added
0.5% citric acid, 0.12% carboxymethyl cellulose sodium, 0.20% sucrose fatty ester, 0.001% ethylmaltol, 40% xylose
Alcohol is uniformly mixed,
(7) particle obtained by step (6) being dried, oven temperature is 60 DEG C, 20 meshes are crossed,
(8) every 10g is that a packet is packaged,
(9) 50mL can be used when eating, 60 DEG C of water is brewed.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5834044A (en) * | 1995-06-07 | 1998-11-10 | Mars, Incorporated | Method of making a health food product containing anti-oxidants |
| US20080268095A1 (en) * | 2007-04-20 | 2008-10-30 | Edmund Clemens Herzog | Dietary Supplement for the Compensation of Nutritional Deficiency |
| CN104997091A (en) * | 2015-06-17 | 2015-10-28 | 桂林丰润莱生物科技有限公司 | Cordyceps militaris instant solid beverage |
| CN106901089A (en) * | 2017-03-08 | 2017-06-30 | 广东食品药品职业学院 | A kind of health drink containing curcumin composition |
| CN108782870A (en) * | 2018-07-17 | 2018-11-13 | 佛山推启农业研究院（普通合伙） | A kind of anti-tumor healthcare tea and preparation method thereof |
-
2019
- 2019-07-08 CN CN201910612195.8A patent/CN110200283A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5834044A (en) * | 1995-06-07 | 1998-11-10 | Mars, Incorporated | Method of making a health food product containing anti-oxidants |
| US20080268095A1 (en) * | 2007-04-20 | 2008-10-30 | Edmund Clemens Herzog | Dietary Supplement for the Compensation of Nutritional Deficiency |
| CN104997091A (en) * | 2015-06-17 | 2015-10-28 | 桂林丰润莱生物科技有限公司 | Cordyceps militaris instant solid beverage |
| CN106901089A (en) * | 2017-03-08 | 2017-06-30 | 广东食品药品职业学院 | A kind of health drink containing curcumin composition |
| CN108782870A (en) * | 2018-07-17 | 2018-11-13 | 佛山推启农业研究院（普通合伙） | A kind of anti-tumor healthcare tea and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 孙鹏尧等: "响应面法优化超声波辅助提取姜黄素类化合物工艺及动力学分析", 《中国食品添加剂》 * |
| 徐青等: "蓝莓花青素的提取及分离研究进展", 《食品与生物技术学报》 * |
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