CN1187115A - Endovascular stent - Google Patents
Endovascular stent Download PDFInfo
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- CN1187115A CN1187115A CN96194653A CN96194653A CN1187115A CN 1187115 A CN1187115 A CN 1187115A CN 96194653 A CN96194653 A CN 96194653A CN 96194653 A CN96194653 A CN 96194653A CN 1187115 A CN1187115 A CN 1187115A
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Abstract
An endovascular transplanting plate fixed mould, is made into component structure, including a slender pillar and a plurality of basic tubular components connected on the pillars along the vertica sequence order. Each component cooperates with the pillar to form a closed ring structure, and the components align as a sequence to form a basically cage-shaped tubular structures. Each small outline in which components can reduce the diameter and be easily to pass through the cavity channel is expanded to an expansion diameter capable of jointing with the inner surface of the cavity. The transplanting plate fixed mould of the component structure can be tailored to particular specifications of specific patients. The components are made by flat twist-shaped wires, and then winding into cylinder-shaped, whose free end is connected at the pillars. The components such as airbags can expand from small outline to expansion configuration. In the expansion process, can wipe off the inner surface of the cavity and smooth the tip points and the edges. The quality of the pillars of the transplanting plate fixed mould is significantly greater than the quality of the individual components, which allows the pillars easy to be observed in the X-ray or fluorescence. The component structure allows the extensive changes of the characteristics of transplanting plate fixed moulds, including vertical flexibility, and radial expansion characteristics.
Description
Background of invention
Many medical approaches relate to settles intraluminal prosthesis or can be by settling intraluminal prosthesis as a supplement, and this intraluminal prosthesis is commonly referred to stent (stent), and they can be implanted in an individual intracavity, in other natural lane as blood vessel or patient body.This type of stent is made a tubular basically configuration usually, and can be expanded to a major diameter from a less diameter (low profile).In its low profile configuration, stent can utilize carrying device to advance to the position of waiting to settle this stent by body cavity in inner chamber.Can make stent be expanded to a bigger diameter then, so that engage the inwall of body cavity securely.Remove carrying device then, the stent of transplanting is stayed in the position.By this way, stent can be used to stay open a blood vessel or other natural conduit, and the latter's function may be owing to pathological changes occurring or wound suffers damage.
In enlarging the medical approaches of using stent, wear chamber angioplasty (PTA) with percutaneous and especially to wear chamber coronary angioplasty (PTCA) relevant with percutaneous.PTA and PCTA relate to by the patient artery insertion and operate a dilating catheter, so that the expanded balloon of conduit is placed in the part (narrow) of being obstructed of blood vessel.Force air bag at the part intramedullary expansion that is obstructed then, so that part of blood vessel dilating makes restoration of blood flow pass through blood vessel thus.In the significant complex situations that may cause owing to this kind angioplasty, under considerable occasion, be obstructed again in the position of expansion.By a stent being placed on the position that was subjected to treatment in the blood vessel, may reduce this kind narrow tendency of stenosis again.Therefore, many stents have been proposed and have developed.
United States Patent (USP) 4,800, disclose a kind of like this stent among 882 (Gianturco), wherein formed a tubular stent with an independent continuous metal silk, this tinsel bends to along the tortuous configuration in the plane of the longitudinal extension that will become the stent axis.Can reel the shifting ground around this axis along circumference then, to form a columnar basically surface and this tubular configuration.The stent of Xing Chenging can be considered to form a plurality of C shape sections along the circumference bending like this, each C shape section is connected on its adjacent section at back-flexing portion place, makes each crooked section extend along the opposite circumferencial direction of the curved section that is adjacent.Therefore, C shape curved section does not form closed circumferential loop wire.Prosthese in installing around the air bag of delivery catheter makes stent center on the airbag fold of expansion to its low profile configuration more then.After being installed in stent on the air bag like this, make conduit and stent advance to stenosis, make airbag inflation, so that make stent radially plastically be expanded to preliminary dimension at this place by patient's blood vessel.The C shape configuration of the curved section of stent inevitably and does not stop the resistance of stent to warp-wise pressure with meeting the requirements, and this warp-wise pressure may occur in tremulous pulse carrying out postangioplasty.The radially resistance that increases shrinking by thick (slightly) degree that increases the silk of making stent is a kind of unsafty solution, because this inevitable requirement increases the thickness of stent, this will make the cross section of body cavity narrow down.In addition, the discontinuous hydrodynamics that may tend to disturb in the side surface that forms by stent by the mobile blood of blood vessel, this may induce turbulent flow conversely, finally produces embolus, thrombosis and other serious complex situations.
The difficulty of above-mentioned device is that also when conduit advanced to deployed position by patient's blood vessel, this device was protected seldom the air bag of delivery catheter.When stent and delivery catheter advanced, quite our configuration opened of stent made air bag expose blood vessel wall.Those walls may have the duricrust of atherosclerosis plaque, and these duricrusts may be irregular and sharp keen.Therefore, when stent advanced through duricrust generation place, air bag may be punctured or damage.When air bag expanded subsequently, this may cause balloon rupture, and patient is produced danger.
The difficulty that above-mentioned device produces is that also the structure of its individual thread makes it be difficult for the accurately concrete patient's blood vessel anatomical features or the pathological condition of coupling arrangement stent.In fact, structure only is suitable for the full-length manufacturing.When the full-length of stent was mated patient's anatomical features unsatisfactoryly, the doctor must make great efforts to select one or more in those full-lengths.It is a kind of compromise just leaving nothing to be desired.
Another shortcoming of above-mentioned stent design and other stent with fastened configuration design equally (for example sees EP335, disclosed stent in 341) is near interior prosthese must be placed in the blood vessel arm time, interior prosthese is implanted into one of arm may hinders and flow into another arm.
It is also important that the time is determined between transplanting stage and afterwards for the position of interior prosthese and location.The stent of above-mentioned Gianturco is to be made by an independent elongated silk, it may be difficult to (if being not impossible words) under fluorescence or X ray as seen.
Catalogue of the present invention provide a kind of improved endovascular stent that can overcome above-mentioned shortcoming.
Summary of the invention
According to the present invention, make a kind of stent with the assembly module form, comprise that an elongated pillar becomes vertical sequence to be connected tubular basically assembly module on this pillar with a plurality of.Each assembly and stanchions form a cage structure closely, make these assemblies along sequence alignment, to form a tubular-shaped structures of cage shape basically.Each assembly is made with silk, and is easy to expand into from the low profile configuration of diameter reduction the diameter of an expansion that can engage with the surface of internal cavity of blood vessel or other body cavity.These assemblies can be along single installations of supporting wire and are fixed in succession, and settle with selected interval along supporting wire.
In another aspect of this invention, each independent tube assembly is made with the silk of a tortuous configuration, and this complications configuration is formed the fine filaments section that ground, end connects by the shorter section end of a plurality of quilts.This indentation silk is wound into the columnar basically configuration of assembly, and its free end is connected on the pillar.The elongated sections of each assembly is orientated along its length along pillar basically, and forms the track of closed crooked loop wire along lateral cross section.When assembly was in its low profile configuration, its elongated section was settled closely adjacently and parallel to each other basically each other and is parallel to pillar.
In another aspect of this invention; assembly can be along the pillar setting; make when being in a low profile configuration; its adjacent end can be arranged to closely adjacent each other; seal to form a circumferential of longitudinally extending continuously basically, to comprise and to protect air bag in the tubulose sequence that is contained in assembly.When the anatomical features of waiting to settle device allowed to use the continuous series of this class component, air bag can be protected on its whole length.
In another aspect of the present invention, assembly can make stent be easy to make the specific angiological anatomy feature that is fit to patient along pillar in selected location interval ground assembling.
In still another aspect of the invention, assembly makes vertical section of assembly clean the inner surface of body lumen wall from the configuration that low profile is expanded to expansion, thereby the cusp of blood vessel or edge are polished, and reduces the danger of balloon rupture thus.
In still another aspect of the invention, pillar is made into and has than the remarkable big quality of single component, makes that pillar can be easily with X ray or fluorescence observation.
In still another aspect of the invention, the pillar of coupling assembling can be believed to comprise supporting wire and a plurality of adapter that is arranged separately on the supporting wire, wherein adapter also be used for interconnection assembly silk the end and they are connected supporting wire.The zone that provides a quality to increase is provided adapter, can observe pillar with film radiography by this zone.
In still another aspect of the invention, can tubular separator be set between adapter on the supporting wire so that between assembly, form required interval, provide simultaneously one successive can be with the pillar of film radiography observation.
Catalogue of the present invention provide a kind of prosthese in assembly structure improved that embodies.
Another object of the present invention provides prosthese in a kind of assembly type, and prosthese can be easy to make selected configuration in this, is suitable for concrete patient's blood vessel anatomical features.
Another object of the present invention provides a kind of stent that is easy to film radiography observation.
Another purpose of the present invention provides a kind of structure of stent, wherein the obstruction of side direction arm can be reduced to minimum.
Another purpose of the present invention provides the stent that a kind of air bag can be expanded, and wherein when air bag being introduced in the blood vessel position, this stent provides the protection to air bag.
The description of the drawings
With reference to accompanying drawing from following description above-mentioned and other purpose and the advantage that invention will be more fully understood, in the accompanying drawing:
Fig. 1 is arranged on the illustration figure of signal slightly of prosthese in of the present invention a kind of in the part of being obstructed of blood vessel, and prosthese is in the not expanded configuration of its low profile in this;
Fig. 2 is arranged on the illustration figure of signal slightly of the interior prosthese on the air bag, and this air bag expands and prosthese is expanded to bigger diameter;
Fig. 3 is the illustration figure of signal slightly of a pair of adjacent component of interior prosthese, and illustration connects on supporting wire;
Fig. 4 is arranged on the endovascular part diagrammatic side view that combines the stent of several modifications;
Fig. 5 is the illustration figure that is similar to Fig. 4, and its B-C post is with the plane graph illustration;
Fig. 6 is the section illustration figure of the post area seen along Fig. 4 center line VI-VI;
Fig. 6 A illustration is used for assembly is connected the view in transverse section of another embodiment of the connector ring on the supporting wire;
Fig. 7 is the schematic section of the device seen along Fig. 4 center line VII-VII;
Fig. 8 A-8C schematically illustrates the variation pattern when assembly assembly configuration when the low profile configuration is expanded to the configuration of expansion;
Fig. 9 is the part of a kind of stent that can be by the expansion of alternate mechanism of illustration schematically.
The description of illustrated embodiment
Each assembly 7 is made by silk 13, and its shape and configuration are made cylindrical side face 12 is radially expanded.In order to form assembly, can earlier silk 13 be made the tortuous configuration in plane, then the indentation silk is rolled into the loop wire configuration.The terminal 16 of indentation silk is a free end.The free end 16 of silk 13 can be interconnection, and be connected on the supporting wire 6 by adapter 9.The indentation of each assembly is arranged and can be regarded as and comprise a series of first elongated sections, these first elongated sections interlock with bending section and are connected by these bending sections, these bending sections can be curved (as circles), also can be made up of the short jointing 15 that is connected at bending point 17 places on the elongated sections 14.This track be settled and be formed to connection bending section between elongated section 14 can along the track of closed loop wire 8.Preferably, silk 13 make make bending section will be around imaginary closed loop wire 8 along periphery even interval so that make assembly 7 have uniform intensity in direction along crosscut supporting wire 6.
As schematically illustrative among Fig. 8, when assembly is in the not expanded configuration of its low profile, forming between the adjacent elongated sections 14 bending section 15,17 that connects makes angle [alpha] between the elongated sections 14 near zero degree, and when maximum extension position as Fig. 8 (C) as shown in of assembly expansion, this angle [alpha] is spent near 180.But, should be appreciated that in practice stent preferably should be expanded to and be no more than the configuration shown in Fig. 8 (b).Preferably, the angle [alpha] that forms between the adjacent elongated sections 14 should be at about 45 degree between about 85 degree.The configuration that comprises the connection bending section of bending point 17 can change, to change angle [alpha] or to change its bending section number along periphery around closed curve 8, thereby change the characteristic of assembly 7, comprise changing it, make that prosthese can further be repaired and make in this and meet the specific body cavity 3 that prosthese in this is transplanted into ideally the resistance of pressure loading radially.
Example as an illustration only can be made a stent and comprises the assembly made from the about 0.15 millimeter silk of diameter 7, has the about 1.8 millimeters elongated section 14 of length (being not included in the connection bending section between the adjacent sections 14).When the connection bending section between the adjacent elongated sections 14 was crooked glossily, they can have about 0.15 millimeter radius before expansion.Stent with above-mentioned size can expect can be expanded between about 2.5 to about 4.0 millimeters diameter and can overdistension, and this stent presents significant resistance to radially flattening, and this resistance is that the maximum radial pressure loading that is added on the stent of about 2.5 contractions to about 4.0 millimeters tremulous pulse is much bigger than expecting by the chamber diameter.
In a preferred embodiment, adapter 9 can be made and be installed on the longitudinal supporting silk 6, as by they are screwed in the silk 6 on.Adapter 9 preferably can comprise a ring, and this ring forms enough inner spaces to hold and to surround the free end 16 of silk 13 and can also be connected securely on the longitudinal supporting silk 6 encircling simultaneously.The free end 16 of ring adapter 9, silk can utilize nonvolatil distortion such as crimping to be connected securely with supporting wire 6, perhaps can be together fastened to each other by spot welding.Shown in Fig. 5 mid point 51, preferably adopt laser spot welding.When adopting the laser spot welding assembling, preferably the terminal part 16 with assembly 7 is welded in earlier on the ring 9, then will encircle 9 and be welded on the supporting wire 6.In some cases, may wish to change this stent, make that one or more assemblies (but being not the most last assembly) are not to be securely fixed on the supporting wire 6, and opposite, allow them certain free sliding degree to be arranged along supporting wire 6.This makes can finally adjust module position after this device being placed in the patient's blood vessel, do so if desired.
Fig. 6 is an embodiment of illustration ring 9 in more detail.As shown in the figure, ring 9 can be considered to have one can be smooth basically inner surface 9i and one can become round outer surface 9e so that more easily be fit to columnar basically blood vessel wall.But it is smooth or circular to should be appreciated that surfaces externally and internally 9i, 9e all can make.The cross section of another embodiment of Fig. 6 A illustration connector ring 9, wherein the wall of this ring is made and is limited an interior camber profile, and camber profile is corresponding to the profile of the free end 16 of supporting wire 6 and assembly 7 in this.The outer surface of this embodiment medium ring can have a parallel with it profile.
Above-mentioned structure can ad hoc assemble a stent, so that accurately meet the patient's who waits to settle stent particular anatomical features.Assembly can be located along supporting wire 6 on demand, and can fix with this configuration.Supporting wire can be selected and the vertically flexible of required degree is provided, and available flexible especially silk makes, so that device is placed in the quite not readily accessible body cavity easily.Adopt above-mentioned wherein stent that an independently structure of supporting wire 6 is arranged, can select the rigidity or the flexible degree of supporting wire, make it irrelevant with the silk of making tube assembly.Supporting wire 6 can highly flexible, so that the stent of its supporting is by narrow curved blood vessel, as coronary artery.
Be to be understood that, though currently preferred embodiment of the present invention comprises a metal support silk 6 (as stainless steel silk), assembly structure of the present invention also can be made a kind of like this stent, and supporting wire wherein can be used nonmetallic materials such as polymeric material, as nylon, make.Can select other in suitable description of materials aspect mechanical aspects and biology, comprise that those As time goes on can be at the material that is absorbed by the tissue of blood vessel wall aspect biology.Employing can bio-absorbable supporting wire 6, should select to make its desired mechanical property to keep time enough, so that assembly 7 can be embedded in the blood vessel wall securely.Therefore, assembly structure of the present invention provides material and the performance range that enlarges markedly to discrete component, and each element is selected to provide optimal results.
Connecting ring 9 special when its during around two end section, 16 assemblings of assembly 7 and supporting wire 6 its quality significantly greater than threads 13 the quality of making assembly.Therefore, the zone that comprises connecting ring 9 of pillar will present remarkable silk 13 radiopacities that presented greater than associated component.The radiopacity that enlarges markedly of join domain increased significantly implant during in the radiography control of prosthese 1.It also can make, and prosthese was subjected to radiographic X observation and need use ultrasonic method in the later time in this.The configuration of stent can be made tubular frame 10 to have high mechanical properties and simultaneously device expanded between its low profile and expanded configuration, but wherein the silk 13 of assembly 7 in the method on the normally used radiation level to the X ray substantially transparent.
Fig. 4-6 illustration another characteristics of the present invention wherein before ring being fixed on the supporting wire 6, can make stent 1 have to be arranged on the spacer (part) 50 between the paired ring 9 in succession.Spacer is preferably cylindrical shape and a centre bore is arranged, and can make spacer with silk 6 slips longitudinally on vertical silk 6 of beading mode by this centre bore.When a series of adapters 9 and spacer 50 be placed on the supporting wire 6, in succession the every pair of adapter or spacer can surround mutually.Length that can the predetermined isolated thing so that can accurately control two intervals between the assembly in succession, reduces simultaneously that supporting wire 6 is twisted or impaired danger.An additional result utilizing spacer 50 to obtain is that it makes stent can only utilize two least significant end adapters 9 that are securely fixed on the supporting wire 6 to assemble.In this embodiment, intermediary element (adapter 9 and spacer 50) will be held in place on supporting wire and can not separate.No matter be all adapters 9 or only adapter 9 of least significant end is fixed on the longitudinal supporting silk 6, intermediate spacer 50 does not need directly to be fixed on the silk 6, and can be held in place between its adjacent adapter 9 by its adjacent adapter 9 on the contrary.As the example of size, can be approximately long 1.10 millimeters, 0.30 millimeter of external diameter, about 0.075 millimeter of wall thickness with the cylindrical shape spacer that the device with above-mentioned size uses.
The spacer 50 of circular cross-section can be configured to the rounded outer surface 9e substantial alignment with adjacent connecting ring 9, as shown in Figure 6.Spacer 50 can protrude from outside the inner surface 9i of adapter 9, as shown in Fig. 4 and Fig. 6 in maintenance on the edge.When using with adapter 9 as shown in Fig. 6 A, the outer surface of spacer can form the continuation of outer bend profile in the stage casing of adapter 9.
Use another advantage of spacer 50 to be, with the part that ring extends of passing through of ring and silk, this configuration forms one and presents the pillar of successive elongated quality basically, and its radiopacity is significantly greater than indentation silk 13.
All elements of device should be with compatible and material that can not form micro cell is made, and this micro cell makes arbitrary part of device produce electrochemical corrosion after may be in the device implantable intravascular.Longitudinal supporting silk 6, silk 13 and adapter 9 should have same chemical constituent.The preferential exemplary materials that adopts comprises following various material in the prosthese in making: annealed rustless steel, titanium alloy, golden nickel alloy, nichrome and titanium chrome alloy.
Can handle and be shaped supporting wire 6 and assembly 7, changing its mechanical property and functional character independently of one another, thereby obtain to be suitable for to handle the required configuration of concrete patient's anatomical features.For example, the silk 13 that the forms assembly heat treatment of can annealing is with the ductility of control silk.
One of feature of the present invention is tube assembly 7 is protected the air bag of the balloon catheter 4 that uses in the instrumentation of interior prosthese 1 a mode.When device is installed on the folding catheter air bag and is in the low profile that be fit to transmit during the stage, elongated sections 14 will be in very near state, and will be substantially parallel and apart very near around the side face of air bag.In addition, one tube assembly can longitudinally be arranged in closely, and makes air bag longitudinally also to be subjected to protecting fully along side face in stent.Be directed and after navigating to deployed position at device and conduit 4, the expansion of device makes elongated sections 14 11 stretch and be expanded to body cavity 3 along side face along wall, to clean wall 13 and the surface roughness that may exist polished, particularly comprise sharp keen or hard zone is polished, otherwise these zones may be damaged air bag and may cause the air bag puncture.When the section 14 of assembly was cleaned the wall 11 of passage 3, they produced a significant shear action.
In the example shown in the Figure 4 and 5, the tube assembly of least significant end is configured to opposite configuration.As shown in the figure, the first left tube assembly 7p of this example is reverse, makes the opposite end of the terminal part 16 sensing devices of silk 13, promptly points to adjacent spacer 50.This reverse configuration has reduced the crack that sharp keen edge may still expose or end connector is interior may face toward the danger that blood flow presents.Such crack may be because in the face of blood flow and by the blood embedding, and may cause the development of local thrombus, and this may cause the restenosis of body cavity.
Fig. 7 is another remodeling of illustration schematically, wherein settles one second supporting wire 6 on the radially opposite of first supporting wire 6.Increase by one second supporting wire and can make stent more firm, provide second simultaneously the opaque pillar of radiation height, thus the location of stent during being more convenient for checking.Second supporting wire 6 ' supporting wire 6 is connected on each assembly as the first.For hold second supporting wire 6 ', assembly 7 is formed by two indentation silks, every indentation silk is provided with around the longitudinal axis 2 of stent, to form the part of imaginary cylinderical surface 12.The element segment of each part bending comprises two free ends 16, and each free end is suitable for being loaded in its corresponding adapter 9.
If desired, the silk that is embedded in the stent can apply one deck protective material such as carbon or anticoagulative substance such as heparin.
In another kind can alternate embodiment, stent can be made and can expand by other method, for example makes assembly 7 with a kind of marmem such as nitinol.Stent can be installed electrical impedance heater 5, induces the thermal control expansion of marmem assembly to produce enough heats.A kind of like this device is illustrated schematically among Fig. 9.
Should be appreciated that above-mentioned explanation of the present invention is only predetermined as it illustrate, the skilled person of this technology obviously can make other embodiment, modification and equivalence and not depart from its principle it.
Claims (64)
1. interior prosthese that body cavity is used comprises:
An elongated supporting wire;
A plurality of assemblies are bearing on the supporting wire along the position of supporting wire in order, and each assembly is fixed on the assembly by one and the adapter that is connected on the supporting wire is connected on the supporting wire;
Each assembly forms the circumferential annulus of a closure, and assembly is arranged on the supporting wire, forms one and is essentially tubular configuration;
Assembly is made and can be positioned at endoceliac configuration of radially shrinking from one and be expanded to the configuration of radially having expanded.
2. the interior prosthese described in claim 1 also comprises a spacer on the supporting wire that is installed between at least one pair of assembly.
3. the interior prosthese described in claim 1 is characterized in that, the join domain between assembly and the supporting wire has a quality that its radiopacity is bigger than distensible assembly.
One kind as in claim 2 or 3 each described in prosthese, it is characterized in that the quality of spacer is bigger than assembly, thereby present the radiopacity bigger than assembly.
5. the interior prosthese described in claim 1 is characterized in that, each tube assembly is made by a zigzag silk, and this has a plurality of with the short elongated sections that bending section interlocks that is connected.
6. the interior prosthese described in claim 5 is characterized in that, this zigzag silk has the free terminal portion that is fixed on the adapter, so that zigzag assembly is fixed in its closed circumferential loop wire configuration.
7. the interior prosthese described in claim 6 is characterized in that, this adapter comprises a hole that holds supporting wire, can slide at supporting wire upper edge supporting wire by this hole connector.
8. the interior prosthese described in claim 6 is characterized in that, this adapter comprises a ring, and this ring is suitable for each free terminal and the supporting wire around its associated component.
9. the interior prosthese described in claim 1 or 8 is characterized in that, assembly, adapter and supporting wire are connected with one of crimping or both associating with spot welding.
10. the interior prosthese described in claim 1 is characterized in that, crooked shape is made on the surface radially outward of adapter, so that meet consistent with the curved shape of blood vessel wall.
11. the interior prosthese described in claim 2 is characterized in that the outer surface of spacer is crooked, so that make it meet consistent with the curved shape of body lumen wall.
12. interior prosthese described in claim 11, it is characterized in that, the profile on the surface of the outside exposure of spacer corresponds essentially to the profile that presents to outer surface of its adjacent adapter, presents a smooth basically and successive surface that is suitable for pressing and meeting the body cavity profile thus.
13. the interior prosthese described in claim 1 is characterized in that, described assembly forms the interconnected cage shape of a flexible backbone longitudinally tubular-shaped structures.
14. the interior prosthese described in claim 5 is characterized in that adjacent elongated sections interconnects by arc-shaped bend portion.
15. the interior prosthese described in claim 5 is characterized in that, adjacent elongated sections is by short section and will to lack the bending point that section is connected on the elongated sections interconnection.
16. the interior prosthese described in claim 5 is characterized in that, these bending sections are arranged in along the track of closed loop wire basically equably circumferentially.
17. the interior prosthese described in claim 1 also comprises second a vertical silk that is connected on the assembly and is arranged essentially parallel to described first supporting wire extension.
18. the interior prosthese described in claim 1 is characterized in that at least one assembly or supporting wire have the ductility that is different from another.
19. the interior prosthese described in claim 1 is characterized in that, the assembly, supporting wire and adapter are made with a kind of fully similar material, corrode in the joint portion of these elements avoiding.
20. the interior prosthese described in claim 19 is characterized in that, assembly is made with following a kind of material: annealed rustless steel, titanium alloy, nickel billon, nichrome and titanium chrome alloy.
21. the interior prosthese described in claim 1 is characterized in that interior prosthese scribbles one deck protective material.
22. the interior prosthese described in claim 21 is characterized in that this protective material comprises carbon.
23. the interior prosthese described in claim 1 is characterized in that interior prosthese scribbles medicine.
24. the interior prosthese described in claim 23 is characterized in that this medicine comprises a kind of anticoagulant.
25. the interior prosthese described in claim 6 is characterized in that the end assembly of interior prosthese is fixed on the supporting wire with its free terminal orientation respect to one another.
26. the interior prosthese described in claim 1 is characterized in that assembly is made between expansionary phase and can be out of shape non-resiliently.
27. the interior prosthese described in claim 1, its size can be packed into when being in the low profile configuration in people's the coronary artery, and can be expanded to wall coronarius at intra-arterial and engage.
28. an endoceliac interior prosthese that is placed in the people comprises:
In recognizing prosthese by be configured to form one basically a plurality of elements of tubular configuration make, all elements are made by same material, and interconnectionly do not have the place, joint portion that causes corrosive performance forming.
29. the interior prosthese described in claim 28 is characterized in that these joint portions are formed by one of crimping and spot welding or both.
30. the interior prosthese described in claim 29 is characterized in that described spot welding comprises laser weld.
31. an endovascular stent comprises:
Assembly on a plurality of spaced position that are connected pillar along a pillar, this pillar have significantly the quality greater than assembly, thus this pillar aspect radiography than assembly more significantly as seen.
32. the stent described in claim 31 is characterized in that, all structural details of this stent are made with same material, and wherein the relative mass of element is the function of its size.
33. one kind as any described stent in claim 31 or 32, it is characterized in that, this pillar comprises an elongated supporting wire and a plurality ofly is installed on the supporting wire and is connected adapter on the assembly.
34. the stent described in claim 33 comprises that also at least one is arranged on the spacer between pair of connectors on the supporting wire, is used for the parts that can expand that adapter is relevant with them and separates.
35. stent described in claim 2, it is characterized in that, each terminal unit firmly is connected on the supporting wire, and wherein at least one is not to be rigidly connected on the supporting wire in the adapter between the assembly endways, and the lengthwise position of described revocable adapter is by its adjacent spacer decision.
36. the carrying device of stent and use thereof, this assembly comprises:
A delivery catheter that has a distensible air bag at its far-end;
A stent, comprise an elongated supporting wire, a plurality ofly be bearing in assembly on the supporting wire with interval location along supporting wire, each assembly is fixed on the assembly by one and the adapter that is connected on the supporting wire is connected on the supporting wire, each assembly forms the circumferential loop wire of a closure, forming a tubular basically configuration, make and can be convenient in body cavity localized configuration of radially shrinking from one and be expanded to a configuration of radially having expanded by these assemblies on supporting wire for these arrangement of components;
At least some assemblies are set at close proximity each other longitudinally, to center on and the protection air bag.
37. a stent and the carrying device thereof described in claim 36 also comprises:
Each assembly of stent is made by an indentation silk, and this indentation silk has a plurality of elongated sections of interlocking with shorter bending section, and the elongated sections in each assembly longitudinally closely is adjacent to mutually settle with the protection relation that air bag is become to center on abreast.
A 38. stent and carrying device thereof described in claim 37, it is characterized in that, the elongated sections of stent is made like this, when airbag aeration makes the stent expansion, the elongated sections of stent will trail and clean the surface of internal cavity of blood vessel, so that the surface of internal cavity of tremulous pulse is smooth.
39. the interior prosthese that body cavity is used comprises:
An elongated supporting wire;
A plurality of assemblies that are arranged on the interval location place along supporting wire;
Be used for each assembly is connected to mechanism on the supporting wire;
Each assembly forms the circumferential loop wire of a closure, and these assemblies are arranged on the supporting wire, form a tubular basically configuration;
These assemblies are made and can be expanded to a configuration of having expanded from a low profile.
40. the interior prosthese described in claim 39 is characterized in that, these assemblies are made and can be expanded to the configuration that it has been expanded from its low profile non-resiliently.
41. make the method that a kind of endovascular stent is used, comprising for one kind:
An elongated supporting wire is provided;
A plurality of assemblies are provided, and each forms the circumferential loop wire of a closure;
An adapter is provided, is used for each assembly is connected supporting wire;
Adapter is connected on its relevant assembly;
Length along supporting wire links together assembly, supporting wire and adapter at selected interval location place.
42. the method described in claim 41 is characterized in that, step of connecting comprises an independent assembly and relevant adapter thereof is connected on the supporting wire simultaneously.
43. the method described in claim 41 is characterized in that, at first assembly is connected to form a sub-device on the adapter, then sub-device is connected on the supporting wire.
44. the method described in claim 41 also comprises:
Spacer is inserted on the supporting wire each between the adjacent adapter, thereby between adjacent adapter, forms at interval.
45. the method described in claim 42 is characterized in that these spacers have equal lengths basically.
46. the method described in claim 41 is characterized in that all supporting wires, assembly and adapter are all made by identical materials.
47. the method described in claim 46 is characterized in that, spacer is by making with the adapter identical materials.
48. the interior prosthese described in claim 5 is characterized in that, the connection bending section of these assemblies centers on closed loop wire basically equably along peripheral intervals.
49. the interior prosthese described in claim 1 also comprises one second longitudinal supporting silk.
50. the interior prosthese described in claim 5 is characterized in that, the silk that forms assembly is at least handled, and produces ductility to impel it.
51. the interior prosthese described in claim 1 is characterized in that adapter comprises a ring with inner surface and opposite outer, this outer surface is circular, is suitable for meeting the normal cylindrical wall of blood vessel.
52. the interior prosthese described in claim 51 is characterized in that the inner surface of this ring is smooth basically.
53. interior prosthese described in claim 51, also comprise a spacer element that is arranged on contiguous a connector on the supporting wire, the outer surface of this spacer element forms a circular contour, and the latter corresponds essentially to the profile that the outer surface by connector ring presents.
54. the method that interior prosthese insertion body cavity is used comprises:
With the interior prosthese of conduit insertion that the air bag of a contraction is arranged, prosthese comprises the tube assembly that can expand of a sequence by a longitudinal supporting silk carrying in this;
This conduit and interior prosthese are inserted in the passage of live body;
Expand prosthese in this simultaneously and make the surface of the smooth body lumen wall of prosthese in this;
Continue expansion and be somebody's turn to do interior prosthese, prosthese combines securely with conduit wall in making.
55. a method that is used to insert prosthese in the blood vessel comprises:
Pre-determine the anatomical features of waiting to settle the blood vessel of prosthese in this;
Make an interior prosthese with reference to described fixed crown anatomical features with kit form then, method provides a longitudinal supporting silk and a plurality of tube assemblies that can radially expand is installed on the supporting wire, selects and settle these assemblies along supporting wire with being consistent with described definite anatomical features;
Interior prosthese is installed on the delivery catheter;
Make delivery catheter advance to predetermined installation position.
56. interior prosthese described in claim 1, it is characterized in that, at least with supporting wire on the bonded adapter of connector assembly be fixed on this supporting wire, at least one endways the adapter between the assembly be not fixed on the supporting wire, thereby at least one loose assembly is longitudinally slided along at least a portion supporting wire.
57. the interior prosthese described in claim 1 also comprises:
At least one can make assembly slide along at least a portion supporting wire with a bonded adapter of assembly that is connected on the supporting wire.
58. the interior prosthese described in claim 1 also comprises:
One second elongated supporting wire is parallel to the elongated supporting wire of mentioning for the first time and extends, and combines with at least some assemblies;
Each and the bonded assembly of second supporting wire divide section to form, they form closed circumferential loop wire together, each and the bonded section of second supporting wire are connected on second supporting wire by an adapter, and this adapter is fixed on the section and is connected on second supporting wire.
59. the interior prosthese described in claim 8 is characterized in that, the interior profile of ring is suitable for closely centering on and meeting basically the outline of free terminal and supporting wire.
60. the endovascular stent described in claim 31 also comprises at least one additional pillar, its quality is significantly greater than assembly, and this additional pillar is parallel to the pillar of mentioning for the first time and extends.
61. the interior prosthese described in claim 1 is characterized in that this elongated supporting wire is made by a kind of nonmetallic materials at least.
62. the interior prosthese described in claim 61 is characterized in that these nonmetallic materials comprise a kind of polymeric material.
63. the interior prosthese described in claim 62 is characterized in that this material comprises nylon.
64. the interior prosthese described in claim 62 is characterized in that, but the used material of elongated supporting wire comprises a kind of material of bio-absorbable.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96194653A CN1187115A (en) | 1995-06-08 | 1996-06-07 | Endovascular stent |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITB095A000292 | 1995-06-08 | ||
| ITB096A000202 | 1996-04-15 | ||
| ITB096A000201 | 1996-04-15 | ||
| CN96194653A CN1187115A (en) | 1995-06-08 | 1996-06-07 | Endovascular stent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1187115A true CN1187115A (en) | 1998-07-08 |
Family
ID=5128760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96194653A Pending CN1187115A (en) | 1995-06-08 | 1996-06-07 | Endovascular stent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1187115A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103607980A (en) * | 2011-04-29 | 2014-02-26 | 艾维希奥医学设备无限责任公司 | Endovascular prosthesis and delivery device |
| CN104768502A (en) * | 2012-11-12 | 2015-07-08 | 美敦力瓦斯科尔勒公司 | Helical stent with orthogonal end and method of forming stent |
| CN105816209A (en) * | 2015-01-22 | 2016-08-03 | 蛇牌股份公司 | Stent retractor/distractor |
| US11154287B2 (en) | 2016-09-30 | 2021-10-26 | Aesculap Ag | Retractor having a puzzle-type connection |
-
1996
- 1996-06-07 CN CN96194653A patent/CN1187115A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103607980A (en) * | 2011-04-29 | 2014-02-26 | 艾维希奥医学设备无限责任公司 | Endovascular prosthesis and delivery device |
| CN104768502A (en) * | 2012-11-12 | 2015-07-08 | 美敦力瓦斯科尔勒公司 | Helical stent with orthogonal end and method of forming stent |
| CN105816209A (en) * | 2015-01-22 | 2016-08-03 | 蛇牌股份公司 | Stent retractor/distractor |
| CN105816209B (en) * | 2015-01-22 | 2021-03-26 | 蛇牌股份公司 | Stent retractor/distractor |
| US11266392B2 (en) | 2015-01-22 | 2022-03-08 | Aesculap Ag | Stent retractor/distractor |
| US11154287B2 (en) | 2016-09-30 | 2021-10-26 | Aesculap Ag | Retractor having a puzzle-type connection |
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