CN115634194A - Carbomer gynecological lotion and preparation method thereof - Google Patents
Carbomer gynecological lotion and preparation method thereof Download PDFInfo
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- CN115634194A CN115634194A CN202211287713.1A CN202211287713A CN115634194A CN 115634194 A CN115634194 A CN 115634194A CN 202211287713 A CN202211287713 A CN 202211287713A CN 115634194 A CN115634194 A CN 115634194A
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- carbomer
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- gynecological lotion
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention discloses carbomer gynecological lotion and a preparation method thereof, wherein the carbomer gynecological lotion comprises the following components in parts by mass: 5-9% of carbomer solution, 1-3% of triethanolamine, 2-6% of glycerol, 1-3% of vitamin E acetate and the balance of purified water. The carbomer gynecological lotion can provide a moist-healing environment for a patient affected part to promote wound healing, low-molecular glycoprotein endogenous interferon is induced to be generated by erosion tissue cells through carbomer high-molecular materials in the lotion, and the lotion has the advantages of antivirus, immunity regulation, inflammation diminishing, healing promotion, better cross-linking property, quicker drug release, more lasting slow release and better linearity, breaks through the limitation of traditional medicines for treating cervical erosion, overcomes the defects that antibacterial or non-antibacterial medicines singly prevent infection or singly promote healing and cannot realize synergistic effect, and improves nursing and treating effects on gynecological diseases.
Description
Technical Field
The invention relates to the technical field of gynecological lotion, and particularly relates to carbomer gynecological lotion and a preparation method thereof.
Background
Gynecological diseases are diseases commonly encountered in the married and fertile women in the same will, and seriously affect the health of the women in the same will. In the prior art, various treatment means including oral medicines and operations (including laser and cryotherapy) exist, but the treatment means are limited by the side effects of the medicines and the operations and the problems of indications, and the treatment means are mostly used for hospital prescription treatment. On the other hand, the key to gynecological diseases is the daily prevention and maintenance.
The gynecological lotion is one of important liquid medicines for daily nursing and treatment of gynecological diseases, is represented as a water solution, and can effectively relieve symptoms such as pruritus, pain, abnormal leucorrhea, pudendum odor and the like caused by vaginitis and cervicitis. Wherein the composition also comprises bacterial vaginitis, trichomonas vaginitis, mixed vaginitis, gonococcal infection and chronic cervicitis; has antiinflammatory, antibacterial, and antipruritic effects. Has obvious inhibiting effect on the growth of pathogenic microorganisms such as staphylococcus aureus, escherichia coli, gonococcus, candida albicans, fungi, saccharomycetes and the like.
In the prior art, most of common gynecological lotion in the market today has low cross-linking property, short slow release time, large treatment limitation and single drug effect, and only can achieve one effect of preventing infection or promoting healing, and cannot achieve synergistic effect, so that the nursing and treatment effects on gynecological diseases are low, and the use requirements cannot be met.
Disclosure of Invention
The invention aims to provide carbomer gynecological lotion and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: carbomer gynecological lotion comprises the following components in parts by weight: 5-9% of carbomer solution, 1-3% of triethanolamine, 2-6% of glycerol, 1-3% of vitamin E acetate and the balance of purified water.
Preferably, the carbomer gynecological lotion further comprises a pH regulator, so that the pH value of the carbomer gynecological lotion is regulated to be 4.0-4.5.
Preferably, the PH adjusting agent is citric acid.
Preferably, the carbomer gynecological lotion is applied to bacterial vaginosis and vulvovaginal candidiasis (vulvovaginal candidiasis) and symptoms of pruritus, pain, abnormal leucorrhea and pudendum odor caused by the bacterial vaginosis and the vulvovaginal candidiasis.
A preparation method of carbomer gynecological lotion comprises the following steps:
pouring constant-temperature purified water into a stirring pot, then sequentially adding a carbomer solution, triethanolamine, glycerol and vitamin E acetate, and fully stirring to obtain a mixed solution;
and step two, adding a proper amount of pH regulator into the mixed solution obtained in the step one, fully stirring again to adjust the pH value of the mixed solution to be 4.0-4.5, simultaneously obtaining uniformly stirred mixed solution, and filling the mixed solution into a packaged liquid storage bottle to obtain the carbomer gynecological lotion.
Preferably, in said first step, the temperature in the stirred tank is maintained at a further 60 ℃ to 75 ℃.
Preferably, the stirring speed of the stirring pot is 600r/min-1000r/min, and the stirring time is 20-40min.
The invention has the technical effects and advantages that:
the carbomer gynecological lotion can provide a moisturizing environment for patients to promote wound healing, low-molecular glycoprotein endogenous interferon is induced to be generated by erosion histiocytes through carbomer high-molecular materials in the lotion, and the lotion has the advantages of antivirus, immunity regulation, inflammation diminishing, healing promotion, better crosslinking property, quicker drug release, more lasting slow release and better linearity, breaks through the limitation of traditional medicines for treating cervical erosion, overcomes the defects that antibacterial or non-antibacterial medicines singly prevent infection or singly promote healing and cannot realize synergistic effect, and improves nursing and treating effects on gynecological diseases.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides carbomer gynecological lotion which comprises the following components in parts by weight: 5-9% of carbomer solution, 1-3% of triethanolamine, 2-6% of glycerol, 1-3% of vitamin E acetate and the balance of purified water;
the carbomer gynecological lotion also comprises a pH regulator which is used for regulating the pH value of the carbomer gynecological lotion to 4.0-4.5 and citric acid;
carbomer gynecological lotion is applied to bacterial vaginosis, vulvovaginal candidiasis (vulvovaginal candidiasis) and symptoms of pruritus, pain, abnormal leucorrhea and pudendum odor caused by the bacterial vaginosis, the vulvovaginal candidiasis and the vulvovaginal candidiasis;
the gynecological lotion is suitable for patients with cervicitis, vaginitis and cervical erosion symptoms, and can promote healing of wound surface of cervical erosion, bacterial vaginitis, candidal vaginitis, mycotic vaginitis, and I/II degree cervical erosion, improve vaginal atrophy and vaginal dryness, and increase vaginal elasticity;
wherein the storage environment is required to be stored in a cool and dry place while keeping the place sealed and protected from light, and women during menstruation need to stop using the sanitary towel.
A preparation method of carbomer gynecological lotion comprises the following steps:
pouring constant-temperature purified water into a stirring pot, then sequentially adding a carbomer solution, triethanolamine, glycerol and vitamin E acetate, and fully stirring to obtain a mixed solution;
and step two, adding a proper amount of pH regulator into the mixed solution obtained in the step one, fully stirring again to adjust the pH value of the mixed solution to be 4.0-4.5, simultaneously obtaining uniformly stirred mixed solution, and filling the mixed solution into a packaged liquid storage bottle to obtain the carbomer gynecological lotion.
In the first step, the temperature in the stirring pot is maintained to be 60-75 ℃, the stirring speed of the stirring pot is 600-1000 r/min, and the stirring time is 20-40min.
Example 1
Sequentially adding 5g of carbomer solution, 1g of triethanolamine, 2g of glycerol, 1g of vitamin E acetate and 500ml of purified water into a stirring pot, and simultaneously keeping the temperature of the stirring pot at 60 ℃ and the rotating speed at 700r/min to fully stir the added materials to obtain a uniformly stirred mixed solution;
and then dripping citric acid into the mixed solution to be used as a pH regulator, adjusting the pH value of the mixed solution to 4.2 so as to obtain carbomer gynecological lotion, and finally filling the carbomer gynecological lotion into a medicine liquid bottle for packaging.
Example 2
Sequentially adding 8g of carbomer solution, 1.6g of triethanolamine, 4.6g of glycerol, 1.5g of vitamin E acetate and 1200ml of purified water into a stirring pot, and fully stirring the added materials while keeping the temperature of the stirring pot at 70 ℃ and the rotating speed at 900r/min to obtain a uniformly stirred mixed solution;
and then dripping citric acid into the mixed solution to be used as a pH regulator, adjusting the pH value of the mixed solution to 4.5 so as to obtain carbomer gynecological lotion, and finally filling the carbomer gynecological lotion into a medicine liquid bottle for packaging.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (7)
1. The carbomer gynecological lotion is characterized by comprising the following components in parts by mass: 5-9% of carbomer solution, 1-3% of triethanolamine, 2-6% of glycerol, 1-3% of vitamin E acetate and the balance of purified water.
2. The carbomer gynecological lotion of claim 1, wherein said carbomer gynecological lotion further comprises a PH adjusting agent for adjusting the PH of the carbomer gynecological lotion to a PH of 4.0 to 4.5.
3. The carbomer gynecological lotion as in claim 1, wherein the PH modifying agent is citric acid.
4. Carbomer gynecological lotion according to claim 1, characterized in that it is used in bacterial vaginosis and vulvovaginal candidiasis (vulvovaginal candidiasis) and the symptoms of itching, pain, abnormal leucorrhea, vulvar odor caused by the above conditions.
5. A method of preparing carbomer gynecological lotion according to any one of claims 1 to 3, characterized in that it comprises the following steps:
pouring constant-temperature purified water into a stirring pot, then sequentially adding a carbomer solution, triethanolamine, glycerol and vitamin E acetate, and fully stirring to obtain a mixed solution;
and step two, adding a proper amount of pH regulator into the mixed solution obtained in the step one, fully stirring again to adjust the pH value of the mixed solution to be 4.0-4.5, simultaneously obtaining uniformly stirred mixed solution, and filling the mixed solution into a packaged liquid storage bottle to obtain the carbomer gynecological lotion.
6. The method for preparing carbomer gynecological lotion according to claim 5, wherein in the first step, the temperature in the stirring kettle is maintained at 60 ℃ to 75 ℃.
7. The method for preparing carbomer gynecological lotion according to claim 5, wherein the stirring speed of the stirring kettle is 600r/min to 1000r/min and the stirring time is 20 to 40min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211287713.1A CN115634194A (en) | 2022-10-20 | 2022-10-20 | Carbomer gynecological lotion and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211287713.1A CN115634194A (en) | 2022-10-20 | 2022-10-20 | Carbomer gynecological lotion and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115634194A true CN115634194A (en) | 2023-01-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202211287713.1A Pending CN115634194A (en) | 2022-10-20 | 2022-10-20 | Carbomer gynecological lotion and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102764267A (en) * | 2011-05-06 | 2012-11-07 | 董未谦 | Carbomer cervical gel |
| CN102988410A (en) * | 2011-09-19 | 2013-03-27 | 娄飞 | Carbomer gel and preparation method thereof |
| WO2019020367A1 (en) * | 2017-07-27 | 2019-01-31 | Farma-Derma S.R.L. | Composition for the treatment of bacterial vaginosis |
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2022
- 2022-10-20 CN CN202211287713.1A patent/CN115634194A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102764267A (en) * | 2011-05-06 | 2012-11-07 | 董未谦 | Carbomer cervical gel |
| CN102988410A (en) * | 2011-09-19 | 2013-03-27 | 娄飞 | Carbomer gel and preparation method thereof |
| WO2019020367A1 (en) * | 2017-07-27 | 2019-01-31 | Farma-Derma S.R.L. | Composition for the treatment of bacterial vaginosis |
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