CN114787151A - 喹唑啉衍生物或其盐、或其药物组合物的用途 - Google Patents
喹唑啉衍生物或其盐、或其药物组合物的用途 Download PDFInfo
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- CN114787151A CN114787151A CN202080071551.0A CN202080071551A CN114787151A CN 114787151 A CN114787151 A CN 114787151A CN 202080071551 A CN202080071551 A CN 202080071551A CN 114787151 A CN114787151 A CN 114787151A
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Organic Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
一种喹唑啉衍生物或其可药用盐、或其固体药物组合物的用途，具体而言涉及式(I)所示的N6‑(1‑丙烯酰基氮杂环己烷‑4‑基)‑N4‑(3‑氯‑4‑氟苯基)‑7‑甲氧基喹唑啉‑4,6‑二胺或其可药用盐、或其固体药物组合物的用途。
Description
PCT国内申请，说明书已公开。
Claims (15)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2019110594719 | 2019-11-01 | ||
| CN201911059471 | 2019-11-01 | ||
| PCT/CN2020/125384 WO2021083347A1 (zh) | 2019-11-01 | 2020-10-30 | 喹唑啉衍生物或其盐、或其药物组合物的用途 |
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| Publication Number | Publication Date |
|---|---|
| CN114787151A true CN114787151A (zh) | 2022-07-22 |
| CN114787151B CN114787151B (zh) | 2024-04-16 |
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Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN114787151B (zh) |
| WO (1) | WO2021083347A1 (zh) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015043515A1 (zh) * | 2013-09-28 | 2015-04-02 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物及其制备方法 |
| WO2016150340A1 (zh) * | 2015-03-20 | 2016-09-29 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物的盐及其制备方法 |
| WO2018036539A1 (zh) * | 2016-08-25 | 2018-03-01 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物的盐的晶体 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA018716B1 (ru) * | 2007-10-29 | 2013-10-30 | Натко Фарма Лимитед | Новые 4-(тетразол-5-ил) хиназолиновые производные в качестве противораковых средств |
-
2020
- 2020-10-30 CN CN202080071551.0A patent/CN114787151B/zh active Active
- 2020-10-30 WO PCT/CN2020/125384 patent/WO2021083347A1/zh active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015043515A1 (zh) * | 2013-09-28 | 2015-04-02 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物及其制备方法 |
| WO2016150340A1 (zh) * | 2015-03-20 | 2016-09-29 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物的盐及其制备方法 |
| WO2018036539A1 (zh) * | 2016-08-25 | 2018-03-01 | 正大天晴药业集团股份有限公司 | 喹唑啉衍生物的盐的晶体 |
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| Publication number | Publication date |
|---|---|
| WO2021083347A1 (zh) | 2021-05-06 |
| CN114787151B (zh) | 2024-04-16 |
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