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CN114762611A - Processing method of multiple dynamic parameters of body and application of processing method in ejection fraction - Google Patents

Processing method of multiple dynamic parameters of body and application of processing method in ejection fraction Download PDF

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CN114762611A
CN114762611A CN202110638976.1A CN202110638976A CN114762611A CN 114762611 A CN114762611 A CN 114762611A CN 202110638976 A CN202110638976 A CN 202110638976A CN 114762611 A CN114762611 A CN 114762611A
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尹立雪
常传礼
甘建红
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Chengdu Healson Technology Co ltd
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Abstract

The method for processing multiple dynamic parameters of the human body and the application of the method to ejection fraction acquire myoelectric, sound and M-ultrasonic signals by equipment which simultaneously acquires myoelectric signals, sound signals and M-ultrasonic images and comprehensively analyze the signals to obtain the accurate motion state of the human body. Particularly, by monitoring the electrocardiosignals, the cardiac ultrasonic images and the heartbeat sounds simultaneously and processing the electrocardiosignals, the cardiac ultrasonic images and the heartbeat sound signals to align time, the minimum distance and the maximum distance between the front wall and the rear wall of the left ventricle of the heart can be found in the cardiac ultrasonic images more accurately, and the minimum volume of contraction of the left ventricle of the heart and the maximum volume of the left ventricle of the heart during expansion are obtained through calculation so as to calculate the ejection fraction of the heart.

Description

肌体多动态参数的处理方法及在射血分数上的应用The processing method of multiple dynamic parameters of the body and its application in ejection fraction

技术领域technical field

本发明涉及到一种医疗设备及信号的处理方法及其应用。The present invention relates to a medical device, a signal processing method and its application.

背景技术Background technique

人体肌体(包括其它动物机体)在运动过程中,会通过大脑的指挥产生肌肉电,以下称肌电。肌电驳动人体肌体运动。心电也是肌电的一种,心电使心脏跳动。The human body (including other animal bodies) will generate muscle electricity through the command of the brain during exercise, hereinafter referred to as myoelectricity. Myoelectricity stimulates the movement of the human body. ECG is also a type of electromyography, which makes the heart beat.

现有技术可以很有效地监测到肌电的产生以及电量。通过肌电信号的强度记录下来。例如心电图,即可知道心电的波形。The current technology can effectively monitor the generation of myoelectricity and the amount of electricity. The intensity of the EMG signal was recorded. For example, an electrocardiogram, you can know the waveform of the electrocardiogram.

同时,通过超声图像,我们还可以知道人体肌肉的形态,位置。肌体在运动时,还产生声音,如骨骼接触的声音,心脏跳动的声音等。并且伴随人体运动时,上述肌电产生、肌肉形态变化、声音产生都是协同、相应该产生的。例如心脏的跳动,都是先产生心电,驱动心脏产生跳动的变化,然后心脏碰撞产生声音(心跳声)。At the same time, through ultrasound images, we can also know the shape and position of human muscles. When the body is in motion, it also produces sound, such as the sound of bone contact, the sound of the heart beating, etc. And when the human body moves, the above-mentioned myoelectric generation, muscle morphological changes, and sound generation are all synergistic and should be generated accordingly. For example, the beating of the heart first generates electrocardiogram, which drives the heart to produce changes in beating, and then the heart collides to produce sound (heartbeat sound).

现有的医疗设备能够分别监测到肌电、形态图像、声音,但目前却没有技术将三者同时监测,例如,现有的设备可以通过形态图像用于辅助针对射血分数进行分析。Existing medical equipment can monitor EMG, morphological images, and sound separately, but there is currently no technology to monitor the three at the same time. For example, existing equipment can use morphological images to assist in the analysis of ejection fraction.

射血分数指每搏输出量占心室舒张末期容积量(即心脏前负荷)的百分比,正常值为50-70%,可通过心脏彩超进行检查,是判断心力衰竭类型的重要指征之一。心室射血分数是指心室的每搏输出量占心室舒张末容积的比例。Ejection fraction refers to the percentage of stroke volume in the end-diastolic volume of the ventricle (ie, cardiac preload). The normal value is 50-70%. It can be checked by echocardiography and is one of the important indicators for judging the type of heart failure. The ventricular ejection fraction is the ratio of the stroke volume of the ventricle to the end-diastolic volume of the ventricle.

射血分数是一个容积比率指标,从容积的角度反映的心室的射血功能。Ejection fraction is a volume ratio indicator that reflects the ejection function of the ventricle in terms of volume.

但由于仅为医务人员提供图像信息,上述射血分数的分析,需要医务人员通过图像信息,然后通过自己在图像手动作标记进行测量,然后计算,获得射血分数,不便于快速提供医疗方案。However, since only image information is provided for medical personnel, the above analysis of ejection fraction requires medical personnel to measure the image information, and then mark by their own hand movements in the image, and then calculate to obtain the ejection fraction, which is inconvenient to provide medical solutions quickly.

因此,为了快速获得人体相关状态信息,也为了更好的辅助医务人员,并为了医疗设备对人体的监测信息的准确,我们有必要充分利用好人体运动时分别产生并监测到的肌电、形态图像、声音信息。Therefore, in order to quickly obtain the relevant state information of the human body, to better assist the medical staff, and for the accuracy of the monitoring information of the human body by medical equipment, it is necessary to make full use of the electromyography and morphology generated and monitored when the human body moves. image, sound information.

发明内容SUMMARY OF THE INVENTION

为了解决上述问题,本发明提供了一种收集机体多动态参数处理的方法以及该方法在心脏射血分数分析上的应用。In order to solve the above problems, the present invention provides a method for collecting multiple dynamic parameters of the body and the application of the method in the analysis of cardiac ejection fraction.

其中,提供了一种收集机体多动态参数处理的方法:Among them, a method for collecting multiple dynamic parameters of the body is provided:

采用同时具备超声信号采集功能、肌电信号采集功能、音频信号采集功能的三项中至少两项采集功能的采集装置,从同一机体上采集到超声信号、肌电信号、音频信号中的至少两种信号,并将采集到的信号同步显示在显示装置上;所述的同步为,各信号时实投射到显示装置上,并使投射到显示装置上各信号之间的时间差,等于采集到各信号的采集时间差。At least two of the ultrasonic signal, the electromyography signal, and the audio signal are collected from the same body by using a collection device with at least two collection functions of the ultrasonic signal collection function, the EMG signal collection function, and the audio signal collection function. The collected signals are displayed on the display device synchronously; the synchronization is that each signal is projected on the display device in real time, and the time difference between the signals projected on the display device is equal to the time difference between the signals projected on the display device The acquisition time difference of the signal.

所述的同步显示,具体方法为:The synchronous display, the specific method is:

S1:先获得超声信号、肌电信号、音频信号各自处理所需时长;得到其中的最大时长,然后将其余信号处理的时长与该最大时长对比,获得对比时长;所述的处理所需时长,是从采集到信号的采集时间,直至信号显示在显示装置上这一过程的所需时间。S1: first obtain the required duration for the respective processing of ultrasonic signals, myoelectric signals, and audio signals; obtain the maximum duration among them, then compare the duration of the remaining signal processing with this maximum duration, and obtain the contrast duration; the described processing required duration, It is the required time from the acquisition to the acquisition of the signal until the signal is displayed on the display device.

S2:将处理所需时长为最大时长的信号处理完成后,立即显示;S2: After processing the signal whose processing required duration is the maximum duration, it is displayed immediately;

将其余信号在处理完成,并经过了对比时长后,立即显示。The remaining signals are displayed immediately after the processing is completed and the comparison time has elapsed.

如上所述的一种收集机体多动态参数处理的方法,更进一步说明为:所述的超声信号为心脏M超影像信号;所述的肌电信号为心电QRS波信号、所述的音频信号为心音。The above-mentioned method for collecting multiple dynamic parameters of the body is further described as follows: the ultrasound signal is a cardiac M-ultrasound image signal; the electromyographic signal is an electrocardiogram QRS wave signal, the audio signal for the heart sound.

如上所述的一种收集机体多动态参数处理的方法,更进一步说明为:所述心电QRS波信号拥有最大时长;心电QRS波信号处理所需时长,与其余信号处理的时长之间的对比时长具体为:0.125S。The above-mentioned method for collecting multiple dynamic parameters of the body is further described as follows: the ECG QRS wave signal has a maximum duration; The specific comparison time is: 0.125S.

其中,提供了一种利用多动态参数处理获得心脏射血分数的方法:Among them, a method for obtaining cardiac ejection fraction using multi-dynamic parameter processing is provided:

将同一时间段并从同一机体中连续采集到的心电QRS波,以及,与心电同步发生的心脏形态变化的M超声影像,分布到同一时间轴上并对齐到同一起始时间点;Distribute the ECG QRS waves continuously collected from the same body during the same time period, and the M-ultrasound images of the cardiac morphological changes that occur synchronously with the ECG, and distribute them on the same time axis and align to the same starting time point;

在M超声影像中,在心电QRS波中的Q波、R波、S波之一产生后的第一特定时长后的时间点,获得M超声影像的第一纵向像素列,并在第一纵向像素列中找出左心室前壁内膜与左心室后壁内膜之间的间距的最小值;In the M ultrasound image, at a time point after a first specific time period after one of the Q wave, R wave, and S wave in the electrocardiographic QRS wave is generated, the first longitudinal pixel column of the M ultrasound image is obtained, and the first longitudinal pixel column is obtained at the first longitudinal direction. Find the minimum value of the distance between the intima of the anterior wall of the left ventricle and the intima of the posterior wall of the left ventricle in the pixel column;

在M超声影像中,在心电QRS波中的Q波、R波、S波之一产生后的第二特定时长后的时间点,获得M超声影像的第二纵向像素列,并在第二纵向像素列中找出左心室前壁内膜与左心室后壁内膜之间的间距的最大值;In the M ultrasound image, at a time point after a second specific time period after one of the Q wave, R wave, and S wave in the electrocardiographic QRS wave is generated, the second longitudinal pixel column of the M ultrasound image is obtained, and the second longitudinal pixel column is obtained at the second longitudinal direction. Find the maximum value of the distance between the intima of the anterior wall of the left ventricle and the intima of the posterior wall of the left ventricle in the pixel column;

并通过所述的最小值与最大值,计算出心脏射血分数。And through the minimum and maximum values, the cardiac ejection fraction is calculated.

如上所述的利用多动态参数处理获得心脏射血分数的方法,更进一步说明为:所述的对齐到同一起始时间点,具体为,采用上述权利要求1-4任意一项权利要求所述的方法,将采集到超声信号、肌电信号同步显示在显示装置上;使时实投射到显示装置上的超声信号、肌电信号的显示时间差,等于采集到信号的采集时间差。The above-mentioned method for obtaining cardiac ejection fraction by using multi-dynamic parameter processing is further described as: the alignment to the same starting time point, specifically, using the method described in any one of the above claims 1-4. method, the collected ultrasonic signals and EMG signals are displayed on the display device synchronously; the display time difference of the ultrasonic signals and EMG signals projected to the display device in real time is equal to the collection time difference of the collected signals.

如上所述的利用多动态参数处理获得心脏射血分数的方法,更进一步说明为:所述的心电QRS波,以及M超声影像是通过同时具有心电QRS波与M超声影像采集功能的设备采集到;The above-mentioned method for obtaining cardiac ejection fraction by using multi-dynamic parameter processing is further described as follows: the ECG QRS wave and the M-ultrasound image are obtained by a device having both the ECG QRS wave and the M-ultrasound image acquisition function. collected;

显示装置上设置有持续时间轴和实时状态轴。A continuous time axis and a real-time state axis are provided on the display device.

如上所述的利用多动态参数处理获得心脏射血分数的方法,更进一步说明为:第一特定时长与第二特定时长的计算方法为:分析若干个经二值化处理的M超声影像,标出左心室前壁内膜与左心室后壁内膜之间的间距的最小值出现的时间,并计算出在Q波、R波、S波之一出现的时间与最小值出现的时间的时差,得到第一特定时长;The above-mentioned method for obtaining cardiac ejection fraction using multi-dynamic parameter processing is further described as follows: the calculation method of the first specific time period and the second specific time period is: analyzing a plurality of binarized M ultrasound images, marking Calculate the time when the minimum value of the distance between the anterior intima of the left ventricle and the intima of the posterior wall of the left ventricle appears, and calculate the time difference between the time when one of the Q wave, R wave, and S wave appears and the time when the minimum value appears. , get the first specific duration;

并计算出在Q波、R波、S波之一出现的时间与最大值出现的时间的时差,得到第二特定时长。And calculate the time difference between the time when one of the Q wave, the R wave, and the S wave appears and the time when the maximum value appears, to obtain a second specific time length.

如上所述的利用多动态参数处理获得心脏射血分数的方法,更进一步说明为:获得左心室前壁内膜与左心室后壁内膜之间的间距的最小值与最大值后,通过以下计算公式EF=(EDV-ES)*100%计算出心脏射血分数,其中EF为心脏射血分数,EDV是心脏左心室前后壁内膜最大距离时心脏左心室的最大容积;ES心脏左心室前后壁内膜最小距离时心脏左心室的最小容积;The above-mentioned method for obtaining cardiac ejection fraction by using multi-dynamic parameter processing is further described as follows: after obtaining the minimum and maximum values of the distance between the intima of the anterior wall of the left ventricle and the intima of the posterior wall of the left ventricle, the following steps are used: The calculation formula EF=(EDV-ES)*100% calculates the cardiac ejection fraction, where EF is the cardiac ejection fraction, EDV is the maximum volume of the left ventricle of the heart at the maximum distance between the anterior and posterior intima of the left ventricle of the heart; ES left ventricle of the heart The minimum volume of the left ventricle of the heart at the minimum distance between the anterior and posterior intima;

其中,通过心脏左心室前后壁内膜最小距离,计算出心脏左心室的最大容积;通过心脏左心室前后壁内膜最大距离,计算出心脏左心室最大容积。Among them, the maximum volume of the left ventricle of the heart is calculated through the minimum distance between the anterior and posterior intima of the left ventricle of the heart;

如上所述的利用多动态参数处理获得心脏射血分数的方法,更进一步说明为:M超声影像由:平行于时间轴的横向像素行,垂直于时间轴的纵向像素行组成。The above-mentioned method for obtaining cardiac ejection fraction using multi-dynamic parameter processing is further described as follows: the M-ultrasound image is composed of horizontal pixel rows parallel to the time axis and vertical pixel rows perpendicular to the time axis.

本发明的有益效果:Beneficial effects of the present invention:

通过本发明可以准确获得心脏跳动过程当中,左心室前后壁最大间距与最小间距,从而可以自动获得心脏的射血分数。The invention can accurately obtain the maximum distance and the minimum distance between the anterior and posterior walls of the left ventricle during the beating of the heart, so that the ejection fraction of the heart can be automatically obtained.

通过连续的获得左心室,前后壁最大间距最大间距,可以动态地知道心脏的射血分数的平均值与当前值;以及心脏的射血分数的最大值与最小值。By continuously obtaining the left ventricle, the maximum distance between the anterior and posterior walls, the average and current values of the cardiac ejection fraction, as well as the maximum and minimum values of the cardiac ejection fraction can be dynamically known.

附图说明Description of drawings

图1是示例一中,实现同一装置分别采集到超声图像信息,心跳声、心电的多功能采集装置结构图。FIG. 1 is a structural diagram of a multifunctional acquisition device for realizing the acquisition of ultrasound image information, heartbeat sound, and electrocardiogram by the same device in Example 1.

图2是示例一、示例二中介绍的,多功能采集装置控制原理示意图。FIG. 2 is a schematic diagram of the control principle of the multi-function acquisition device introduced in Example 1 and Example 2.

图3是示例二中,实现同一装置分别采集到超声图像信息,心跳声、心电的多功能采集装置结构图。FIG. 3 is a structural diagram of a multifunctional acquisition device for realizing the acquisition of ultrasound image information, heartbeat sound, and electrocardiogram by the same device in Example 2.

图4是示例三中,采集并处理超声图像信息的采集装置控制原理示意图。FIG. 4 is a schematic diagram of the control principle of the acquisition device for acquiring and processing ultrasound image information in Example 3. FIG.

图5是示例三中,采集并处理超声图像信息的采集装置结构图。FIG. 5 is a structural diagram of an acquisition device for acquiring and processing ultrasound image information in Example 3. FIG.

图6是本发明同步显示具体方法示意图。FIG. 6 is a schematic diagram of a specific method for synchronous display according to the present invention.

具体实施方式Detailed ways

本发明设备及方法主要用于人体,本发明的机体主要指人体,当然,也可以适用于除人体以外的其它动物。以下所述的“人体”是用语习惯的代指。The apparatus and method of the present invention are mainly used for the human body, and the body of the present invention mainly refers to the human body. Of course, it can also be applied to other animals besides the human body. The "human body" described below is a term used to refer to.

本发明的实现,最好是以软件代码的形式实现,将本发明的步骤编辑为软件代码,安装于具有计算功能的计算机,例如,以软件代码的形式,安装于智能手机、平板电脑中,该手机、平板电脑具有能识别和读取M型超声心动图像的功能。The realization of the present invention is preferably realized in the form of software codes, the steps of the present invention are edited into software codes, and installed in a computer with computing functions, for example, in the form of software codes, installed in smart phones, tablet computers, The mobile phone and tablet computer have the function of recognizing and reading M-mode echocardiography images.

本领域普通技术人员可以意识到,结合本文中所公开的实施例描述的各示例算法步骤,能够以电子硬件、或者计算机软件和电子硬件的结合来实现。这些功能究竟以硬件还是软件方式来执行,取决于技术方案的特定应用和设计约束条件。专业技术人员可以对每个特定的应用来使用不同方法来实现所描述的功能,但是这种实现不应认为超出本发明的范围。Those of ordinary skill in the art can realize that each example algorithm step described in conjunction with the embodiments disclosed herein can be implemented in electronic hardware, or a combination of computer software and electronic hardware. Whether these functions are performed in hardware or software depends on the specific application and design constraints of the technical solution. Skilled artisans may implement the described functionality using different methods for each particular application, but such implementations should not be considered beyond the scope of the present invention.

本发明的实现,是通过具有相关硬件的计算机中安装相应的计算机程序来完成,所述的计算机程序可存储于一计算机可读存储介质中,该计算机程序在被处理器执行时,可实现所需的各种步骤。其中,所述计算机程序包括计算机程序代码,所述计算机程序代码可以为源代码形式、对象代码形式、可执行文件或某些中间形式等。所述计算机可读介质可以包括:能够携带所述计算机程序代码的任何实体或装置、记录介质、U盘、移动硬盘、磁碟、光盘、计算机存储器、只读存储器(ROM,Read-Only Memory)、随机存取存储器(RAM,RandomAccess Memory)、电载波信号、电信信号以及软件分发介质等。需要说明的是,所述计算机可读介质包含的内容可以根据司法管辖区内立法和专利实践的要求进行适当的增减,例如在某些司法管辖区,根据立法和专利实践,计算机可读介质不包括是电载波信号和电信信号。The implementation of the present invention is accomplished by installing a corresponding computer program in a computer with relevant hardware, the computer program can be stored in a computer-readable storage medium, and when the computer program is executed by the processor, it can realize the various steps required. Wherein, the computer program includes computer program code, and the computer program code may be in the form of source code, object code, executable file or some intermediate form, and the like. The computer-readable medium may include: any entity or device capable of carrying the computer program code, a recording medium, a U disk, a removable hard disk, a magnetic disk, an optical disk, a computer memory, a read-only memory (ROM, Read-Only Memory) , Random Access Memory (RAM, RandomAccess Memory), electric carrier signal, telecommunication signal and software distribution medium, etc. It should be noted that the content contained in the computer-readable media may be appropriately increased or decreased according to the requirements of legislation and patent practice in the jurisdiction, for example, in some jurisdictions, according to legislation and patent practice, the computer-readable media Excluded are electrical carrier signals and telecommunication signals.

在本发明的计算机,主要的硬件构成仍然包含如下几个主要部分:中央处理器、内存、芯片组、I/O总线、I/O设备、电源、机箱和相关软件,相关软件是指至于能将M型超声心动图(M-mode echocardiography,M-echo)图像投入到显示屏上的软件,当然M型超声心动图也可以不以图像形式显示,而是由计算机后台自行对图像进行处理和计算,最终只在显示器上呈现计算结果。In the computer of the present invention, the main hardware structure still includes the following main parts: central processing unit, memory, chipset, I/O bus, I/O equipment, power supply, chassis and related software, related software refers to the ability to The software that puts the M-mode echocardiography (M-echo) image on the display screen, of course, the M-mode echocardiogram can also not be displayed in the form of images, but the computer background processes and processes the images by itself. calculation, and finally only the calculation result is displayed on the display.

示例一:Example one:

通过设置有超声信号发射及采集的探头、设置有声音采集头、肌电采集电极的多功能采集装置,采集人体的肌体信息。分别采集到超声图像信息,声音信息、肌电信息。具体为,通过设置有超声信号发射及采集的探头、设置有声音采集头、心电采集电极的多功能采集装置,采集人体的心脏跳动信息,分别采集到心脏超声图像信息,心跳声、心电。The body information of the human body is collected through a multi-functional collecting device provided with a probe for transmitting and collecting ultrasonic signals, a sound collecting head and an electromyographic collecting electrode. Ultrasound image information, sound information and electromyography information are collected respectively. Specifically, the heartbeat information of the human body is collected through a multi-functional collection device provided with a probe for transmitting and collecting ultrasonic signals, a sound collection head, and an ECG collection electrode, and the cardiac ultrasound image information, heartbeat sound, ECG, and ECG are respectively collected. .

参考以下装置,可以实现同一装置分别采集到超声图像信息,心跳声、心电。Referring to the following devices, the same device can separately collect ultrasound image information, heartbeat sound, and electrocardiogram.

参考图1,本实施例提供多功能听诊器,包括设备主体5,设备主体5上设有单阵元超声探头2,所述设备主体5上设有心电传感器,设备主体5下端设有充电接口;设备主体5内设有用于控制设备主体5工作、与移动客户终端交互传送数据的控制电路板,以及为整个听诊器主体供电的电源模块,充电接口分别与电源模块连接,电源模块包括可充电电池。Referring to FIG. 1 , the present embodiment provides a multifunctional stethoscope, including a device main body 5 , a single-array element ultrasonic probe 2 is arranged on the device main body 5 , an ECG sensor is arranged on the device main body 5 , and a charging interface is arranged at the lower end of the device main body 5 ; The device main body 5 is provided with a control circuit board for controlling the operation of the device main body 5, interactively transmitting data with the mobile client terminal, and a power supply module for supplying power to the entire stethoscope main body. The charging interfaces are respectively connected to the power supply modules, and the power supply modules include rechargeable batteries.

将单阵元超声探头2和心电传感器集成到一个设备主体5上,使该探头能够实现超声和心电的功能。The single-array element ultrasound probe 2 and the ECG sensor are integrated into a device body 5, so that the probe can realize the functions of ultrasound and ECG.

设备主体5上设有拾音器4,心电传感器为三导联心电电极,三导联心电电极由三个均匀布置在设备主体5前端面的心电电极3组成,单阵元超声探头2位于设备主体5前端面中部,拾音器4位于设备主体5前端面一侧。The device body 5 is provided with a pickup 4, the ECG sensor is a three-lead ECG electrode, and the three-lead ECG electrode is composed of three ECG electrodes 3 evenly arranged on the front end of the device body 5, and a single-array element ultrasonic probe 2 Located in the middle of the front end surface of the device body 5 , the pickup 4 is located on one side of the front end surface of the device body 5 .

通过拾音器4可以实现心音、胎心监测、呼吸音和肠鸣音的检测功能。在实际操作过程中,该听诊器的声音输出可以通过移动客户终端的扬声器,也可以通过与该听诊器连接的蓝牙耳机,同时将波形图显示在移动客户终端的显示器上。The detection function of heart sound, fetal heart rate monitoring, breathing sound and bowel sound can be realized through the pickup 4. During the actual operation, the sound output of the stethoscope can be through the speaker of the mobile client terminal, or through the Bluetooth headset connected with the stethoscope, and the waveform graph can be displayed on the display of the mobile client terminal at the same time.

设备主体5包括由上至下依次连接的上壳体6、主壳体7和下壳体,控制电路板位于主壳体7内部,设备主体5上端设有与其盖合的保护盖1,上壳体6表面设有能够将保护盖1内侧面卡住的卡齿601,上壳体6上面螺接有中空盖401,中空盖401内侧设有位于拾音器4上方的薄膜片402。The device main body 5 includes an upper casing 6, a main casing 7 and a lower casing which are connected in sequence from top to bottom. The control circuit board is located inside the main casing 7. The upper end of the device main body 5 is provided with a protective cover 1 covering it. The surface of the casing 6 is provided with teeth 601 that can clamp the inner side of the protective cover 1 , the upper casing 6 is screwed with a hollow cover 401 , and the inner side of the hollow cover 401 is provided with a membrane 402 located above the pickup 4 .

设备控制电路板以及心电传感器、单阵元超声探头2、拾音器4的结构组成见图2。The structure of the device control circuit board, the ECG sensor, the single-element ultrasonic probe 2, and the pickup 4 is shown in Figure 2.

设备主体5的外壳部分被分为上壳体6、主壳体7和下壳体,能够降低生产工艺难度,设备主体5上端的保护盖1与上壳体6盖合,在不使用时能够避免拾音器4、心电电极3和薄膜片402被异物污损。The shell part of the device body 5 is divided into an upper shell 6, a main shell 7 and a lower shell, which can reduce the difficulty of the production process. Avoid contamination of the pickup 4, the ECG electrodes 3 and the membrane sheet 402 by foreign objects.

控制电路板上设有主控芯片,用于处理单阵元超声探头2、心电传感器和拾音器4的检测数据,并将其转换生成为可读取的数值和曲线形式的数据;数据传输模块用于将主控芯片生成的数据传输给移动客户终端。闪存芯片FLASH,用于将主控芯片生成的数据全部储存起来,闪存芯片FLASH与主控芯片连接。There is a main control chip on the control circuit board, which is used to process the detection data of the single-element ultrasonic probe 2, the ECG sensor and the pickup 4, and convert it into readable data in the form of numerical values and curves; data transmission module It is used to transmit the data generated by the main control chip to the mobile client terminal. The flash memory chip FLASH is used to store all the data generated by the main control chip, and the flash memory chip FLASH is connected with the main control chip.

单阵元超声探头2通过超声通道与主控芯片连接,拾音器4和心电传感器通过复合通道与主控芯片连接,客户终端移动客户终端通过数据传输模块与主控芯片连接。The single-element ultrasonic probe 2 is connected to the main control chip through an ultrasonic channel, the pickup 4 and the ECG sensor are connected to the main control chip through a composite channel, and the mobile client terminal of the client terminal is connected to the main control chip through a data transmission module.

在本实施例中,多功能听诊器能同时采用单阵元超声探头采集到超声图像信息,拾音器4采集到心跳声、心电传感器采集到心电信息。同时三个采集头是同时且基本处于同一位置(例如人体左胸部的心脏处)采集到上述信息,因此,采集到的信息是实时的,是针对同一机体的。In this embodiment, the multi-functional stethoscope can simultaneously use the single-element ultrasonic probe to collect ultrasonic image information, the pickup 4 to collect the heartbeat sound, and the electrocardiogram sensor to collect the electrocardiogram information. At the same time, the three collecting heads collect the above-mentioned information at the same time and basically at the same position (for example, at the heart of the left chest of a human body). Therefore, the collected information is real-time and aimed at the same body.

示例二:Example two:

参考以下中国专利CN209695222U的装置,可以实现同一装置分别采集到超声图像信息,心跳声、心电。Referring to the device of the following Chinese patent CN209695222U, the same device can separately collect ultrasound image information, heartbeat sound, and electrocardiogram.

其结构包括,参考图2、图3:Its structure includes, with reference to Figure 2 and Figure 3:

1、单阵元超声探头,用于检测心脏的射血分数LVEF。心肺功能探头,包括用于检测心率ECG的心电传感器,心电传感器为三导联心电电极,呼吸频率传感器为电容式呼吸传感器。检测呼吸频率RR的呼吸频率传感器。单阵元超声探头通过超声通道与主控芯片连接,心肺功能探头上的心电传感器和呼吸频率传感器均通过复合通道与主控芯片连接,客户终端移动客户终端通过数据传输模块与主控芯片连接,单阵元超声探头和心肺功能探头均位于听诊器主体前端面,心电传感器和呼吸频率传感器并排固定为一体。单阵元超声探头包括:1. Single-element ultrasound probe, used to detect cardiac ejection fraction (LVEF). The cardiopulmonary function probe includes an ECG sensor for detecting heart rate ECG, the ECG sensor is a three-lead ECG electrode, and the respiration rate sensor is a capacitive respiration sensor. Respiratory rate sensor that detects respiratory rate RR. The single-element ultrasonic probe is connected to the main control chip through the ultrasonic channel, the ECG sensor and the respiratory rate sensor on the cardiopulmonary function probe are connected to the main control chip through the composite channel, and the mobile client terminal of the client terminal is connected to the main control chip through the data transmission module. , the single-array element ultrasound probe and the cardiopulmonary function probe are located on the front face of the stethoscope main body, and the ECG sensor and the respiratory rate sensor are fixed side by side as a whole. Single-element ultrasound probes include:

(1)超声换能器,单阵元超声探头包括用于向人体发射超声波并接收回波信号;(2)发射电路,用于控制超声换能器向人体发射超声波;(3)接收电路,用于接收超声换能器的回波信号;(4)接口电路,用于通过超声通道与听诊器主体中的主控芯片连接;(5)控制器,用于控制发射电路工作、检测接收电路中是否有回波信号以及储存回波信号。控制器包括发射控制模块、数据存储模块、接收控制模块和接口控制模块,发射控制模块通过发射控制总线与发射电路连接,数据存储模块与接收电路连接,接收电路通过接收控制总线与接收控制模块连接,接口控制模块与接口电路连接。(6)以及发射控制总线、接收开关电路和接收控制总线。(1) Ultrasonic transducer, the single-array element ultrasonic probe includes a device for transmitting ultrasonic waves to the human body and receiving echo signals; (2) a transmitting circuit for controlling the ultrasonic transducer to transmit ultrasonic waves to the human body; (3) a receiving circuit, It is used to receive the echo signal of the ultrasonic transducer; (4) the interface circuit is used to connect with the main control chip in the main body of the stethoscope through the ultrasonic channel; (5) the controller is used to control the operation of the transmitting circuit and detect the receiving circuit Whether there is an echo signal and store the echo signal. The controller includes a transmission control module, a data storage module, a reception control module and an interface control module. The transmission control module is connected to the transmission circuit through the transmission control bus, the data storage module is connected to the reception circuit, and the reception circuit is connected to the reception control module through the reception control bus. , the interface control module is connected with the interface circuit. (6) and transmit control bus, receive switch circuit and receive control bus.

2、主控芯片,参考图2,用于处理单阵元超声探头、心电传感器和呼吸频率传感器的检测数据,并将其转换生成为可读取的数值和曲线形式的数据。2. The main control chip, referring to Fig. 2, is used to process the detection data of the single-element ultrasonic probe, the ECG sensor and the respiratory rate sensor, and convert it into readable numerical value and data in the form of a curve.

3、数据传输模块,用于将主控芯片生成的数据传输给移动客户终端。3. The data transmission module is used to transmit the data generated by the main control chip to the mobile client terminal.

4、电源模块,用于为整个听诊器主体供电。4. The power module is used to supply power to the entire stethoscope body.

5、电源开关,用于打开或关闭电源模块的供电。5. The power switch is used to turn on or off the power supply of the power module.

6、用于将主控芯片生成的数据全部储存起来的闪存芯片FLASH,闪存芯片FLASH与主控芯片连接。6. The flash memory chip FLASH used to store all the data generated by the main control chip, and the flash memory chip FLASH is connected with the main control chip.

数据传输模块为USB接口和/或蓝牙模块。所述移动客户终端为手机终端。所述心肺功能探头不少于两个。所述听诊器主体为圆柱状。The data transmission module is a USB interface and/or a Bluetooth module. The mobile client terminal is a mobile phone terminal. There are no less than two cardiopulmonary function probes. The stethoscope body is cylindrical.

在实施过程中,将听诊器主体前端面压在病人需要听诊肺部和心脏部位,使听诊器主体前端面的单阵元超声探头、心电传感器和呼吸频率传感器均与听诊部位表面接触,主控芯片分别向单阵元探头、心电传感器和呼吸频率传感器发送进行检测的电信号,单阵元探头、心电传感器和呼吸频率传感器对所在身体部位进行探测并向主控芯片回传探测数据,主控芯片对单阵元探头、心电传感器和呼吸频率传感器回传的探测数据分别进行处理,以实时获取射血分数LVEF、心率ECG和呼吸频率RR的数值,并将连续获取的具体数值转换为曲线。主控芯片将获取射血分数LVEF、心率ECG和呼吸频率RR的数值以及相应的曲线,通过数据传输模块传送到移动客户端,医生在移动客户端上能够实时查看获取呼吸频率RR、心率ECG以及心脏的射血分数LVEF的具体数值。闪存芯片FLASH将主控芯片生成的数值和曲线全部存储起来,主控芯片可通过数据传输模块将闪存芯片FLASH中存储的数值和曲线传输到移动客户终端详细查看分析,能够防止听诊器主体在电源模块意外断电时检测数据丢失。During the implementation process, the front surface of the stethoscope body is pressed against the parts of the patient's lungs and heart that need to be auscultated, so that the single-array ultrasonic probe, ECG sensor and respiratory rate sensor on the front surface of the stethoscope body are in contact with the surface of the auscultation site, and the main control chip Send electrical signals for detection to the single-array element probe, ECG sensor, and respiratory rate sensor respectively. The single-array element probe, ECG sensor, and respiratory rate sensor detect the body part and return the detection data to the main control chip. The control chip processes the detection data returned by the single-array element probe, ECG sensor and respiratory rate sensor respectively to obtain the values of ejection fraction LVEF, heart rate ECG and respiratory rate RR in real time, and converts the continuously obtained specific values into curve. The main control chip will obtain the values of ejection fraction LVEF, heart rate ECG and respiratory rate RR and the corresponding curves, and transmit them to the mobile client through the data transmission module. The doctor can view and obtain the respiratory rate RR, heart rate ECG and The specific value of the cardiac ejection fraction LVEF. The flash memory chip FLASH stores all the values and curves generated by the main control chip. The main control chip can transmit the values and curves stored in the flash memory chip FLASH to the mobile client terminal for detailed viewing and analysis through the data transmission module. Detects data loss in the event of an unexpected power outage.

在使用上述CN209695222U的装置时,需要将呼吸频率传感器更改为示例一中的拾音器4,以实现本发明所需的心跳声采集功能。When using the device of CN209695222U, the respiratory rate sensor needs to be changed to the microphone 4 in Example 1, so as to realize the heartbeat sound collection function required by the present invention.

在本实施例中,多功能听诊器能同时采用单阵元超声探头采集到超声图像信息,拾音器采集到心跳声、心电传感器采集到心电信息。同时三个采集头是同时且基本处于同一位置(例如人体左胸部的心脏处)采集到上述信息,因此,采集到的信息是实时的,是针对同一机体的。In this embodiment, the multifunctional stethoscope can simultaneously use the single-array ultrasonic probe to collect ultrasonic image information, the pickup to collect the heartbeat sound, and the electrocardiographic sensor to collect the electrocardiographic information. At the same time, the three collecting heads collect the above-mentioned information at the same time and basically at the same position (for example, at the heart of the left chest of a human body). Therefore, the collected information is real-time and aimed at the same body.

示例三:Example three:

上述示例一、二中,均需要处理超声图像信息,采集超声图像信息,可以参考以下中国专利CN209751086U的装置,可以实现采集到超声图像信息,并处理超声图像信息。参考图4、图5。In the above examples 1 and 2, ultrasonic image information needs to be processed and ultrasonic image information is collected, and the device of the following Chinese patent CN209751086U can be referred to, which can collect ultrasonic image information and process ultrasonic image information. Refer to Figure 4 and Figure 5.

本实施例包括用于发出扫描波束的超声换能器,用于控制超声换能器发出扫描波束以及采集回波信号的数字控制处理芯片,用于向数字控制处理芯片发出控制指令和查看扫描图像的便携式控制终端,以及发射接收复用电路、发射接收切换电路、发射电路、接收电路、USB接口电路、低电源模块和超声仪壳体。This embodiment includes an ultrasonic transducer for sending out a scanning beam, a digital control processing chip for controlling the ultrasonic transducer to send out a scanning beam and collecting echo signals, for sending control instructions to the digital control processing chip and viewing the scanned image The portable control terminal, and transmit-receive multiplexing circuit, transmit-receive switching circuit, transmit circuit, receive circuit, USB interface circuit, low power module and ultrasound instrument shell.

所述发射接收切换电路、发射接收复用电路和超声换能器依次串联,发射电路和接收电路分别与发射接收切换电路连接,超声换能器、数字控制处理芯片、发射接收复用电路、发射接收切换电路、发射电路、接收电路和USB接口电路均封装在超声仪壳体中,超声换能器位于超声仪壳体前端,超声仪壳体前端面为耦合平面,USB接口电路位于超声仪壳体后端。The transmit-receive switching circuit, the transmit-receive multiplexing circuit and the ultrasonic transducer are connected in series in sequence, and the transmit circuit and the receive circuit are respectively connected with the transmit-receive switch circuit. The receiving switching circuit, the transmitting circuit, the receiving circuit and the USB interface circuit are all encapsulated in the ultrasonic instrument shell. The ultrasonic transducer is located at the front end of the ultrasonic instrument case. The front end of the ultrasonic instrument case is a coupling plane, and the USB interface circuit is located in the ultrasonic instrument case. rear end of the body.

所述低电源模块中设有:The low power module is provided with:

1、数字电源,用于为数字控制处理芯片、发射接收切换电路、发射电路和发射接收复用电路提供适配的电能,数字电源中设有用于保护其电压稳定的线性电压调节器,数字控制处理芯片、发射接收切换电路、发射电路和发射接收复用电路分别与数字电源连接;1. The digital power supply is used to provide suitable power for the digital control processing chip, the transmitting and receiving switching circuit, the transmitting circuit and the transmitting and receiving multiplexing circuit. The digital power supply is provided with a linear voltage regulator to protect its voltage stability, and the digital control The processing chip, the transmitting and receiving switching circuit, the transmitting circuit and the transmitting and receiving multiplexing circuit are respectively connected with the digital power supply;

2、模拟电源,用于为发射接收复用电路和接收电路提供适配的电能,模拟电源中设有用于保护其电压稳定的线性电压调节器,发射接收复用电路和接收电路分别与模拟电源连接;2. The analog power supply is used to provide suitable power for the transmitting and receiving multiplexing circuit and the receiving circuit. The analog power supply is provided with a linear voltage regulator to protect its voltage stability. The transmitting and receiving multiplexing circuit and the receiving circuit are respectively connected with the analog power supply. connect;

3、可调高压DC转换器,用于为发射电路提供适配的高电压,发射电路与可调高压DC转换器连接;3. The adjustable high-voltage DC converter is used to provide a suitable high voltage for the transmitting circuit, and the transmitting circuit is connected with the adjustable high-voltage DC converter;

4、过流保护器,用于限制提供给数字电源、模拟电源和可调高压DC转换器的电流强度,数字电源、模拟电源和可调高压DC转换器分别通过过流保护器与USB接口电路连接。4. The overcurrent protector is used to limit the current intensity provided to the digital power supply, the analog power supply and the adjustable high voltage DC converter. The digital power supply, the analog power supply and the adjustable high voltage DC converter pass through the overcurrent protector and the USB interface circuit respectively. connect.

超声仪壳体前端面为耦合平面,数字控制处理芯片中设有:The front surface of the ultrasonic instrument shell is a coupling plane, and the digital control processing chip is provided with:

1、发射波束控制模块,用于控制发射接收切换电路打开发射电路通道和关闭接收电路通道,以及控制超声换能器发出扫描波束,发射波束控制模块通过发射控制总线与发射电路连接。1. The transmit beam control module is used to control the transmit and receive switching circuit to open the transmit circuit channel and close the receive circuit channel, and to control the ultrasonic transducer to send out scanning beams. The transmit beam control module is connected to the transmit circuit through the transmit control bus.

2、接收控制模块,用于检测发射接收复用电路是否有回波信号,以及用于控制发射接收切换电路打开接收电路通道和关闭发射电路通道,发射接收切换电路和发射接收复用电路通过接收控制总线分别与接收控制模块连接。2. The receiving control module is used to detect whether there is an echo signal in the transmitting and receiving multiplexing circuit, and to control the transmitting and receiving switching circuit to open the receiving circuit channel and close the transmitting circuit channel, and the transmitting and receiving switching circuit and the transmitting and receiving multiplexing circuit pass through the receiving circuit. The control bus is respectively connected with the receiving control module.

3、数据处理模块,用于接收和采集回波信号,数据处理模块与接收电路连接;3. The data processing module is used to receive and collect echo signals, and the data processing module is connected to the receiving circuit;

4、接口控制模块,用于控制发射波束控制模块和接收控制模块交替运行,以及将数据处理模块采集的回波信号发送给便携式控制终端,发射波束控制模块和接收控制模块分别与接口控制模块连接,接口控制模块通过USB接口电路与便携式控制终端连接。4. The interface control module is used to control the alternate operation of the transmit beam control module and the receive control module, and to send the echo signals collected by the data processing module to the portable control terminal. The transmit beam control module and the receive control module are respectively connected to the interface control module , the interface control module is connected with the portable control terminal through the USB interface circuit.

数字控制处理芯片为FPGA可编程数字门阵列处理芯片。便携式控制终端为手机终端。The digital control processing chip is an FPGA programmable digital gate array processing chip. The portable control terminal is a mobile phone terminal.

在实施过程中,便携式控制终端通过USB接口电路为超声仪供电,数字电源能够为数字控制处理芯片、发射接收切换电路、发射电路和发射接收复用电路提供适配的电能,模拟电源能够为发射接收复用电路和接收电路提供适配的电能,可调高压DC转换器为发射电路提供适配的高电压,数字电源和模拟电源中均设有用于保护其电压稳定的线性电压调节器。In the implementation process, the portable control terminal supplies power to the ultrasound instrument through the USB interface circuit, the digital power supply can provide suitable power for the digital control processing chip, the transmit-receive switching circuit, the transmit circuit and the transmit-receive multiplexing circuit, and the analog power supply can provide power for the transmit and receive multiplexing circuits. The receiving multiplexing circuit and the receiving circuit provide suitable electrical energy, the adjustable high-voltage DC converter provides suitable high voltage for the transmitting circuit, and both the digital power supply and the analog power supply are provided with linear voltage regulators to protect their voltage stability.

通过便携式控制终端向超声仪发出进行扫描的指令,数字控制处理芯片通过发射电路控制发射接收切换电路打开发射电路通道和关闭接收电路通道,从而控制超声换能器发出扫描波束,超声换能器将获得的回波信号发送给发射接收复用电路。数字控制处理芯片检测到发射接收复用电路有回波信号时,数字控制处理芯片控制发射接收切换电路打开接收电路通道和关闭发射电路通道,回波信号依次通过发射接收切换电路和接收电路发送到数字控制处理芯片,数字控制处理芯片对回波信号进行采集,采集的回波信号依次通过USB接口电路发送到便携式控制终端,便携式控制终端对采集的回波信号进行处理获得超声图像并将其显示出来。Send an instruction to scan to the ultrasound machine through the portable control terminal, and the digital control processing chip controls the transmit-receive switching circuit to open the transmit circuit channel and close the receive circuit channel through the transmit circuit, thereby controlling the ultrasonic transducer to send out a scanning beam, and the ultrasonic transducer will The obtained echo signal is sent to the transmit-receive multiplexing circuit. When the digital control processing chip detects that the transmitting and receiving multiplexing circuit has an echo signal, the digital control processing chip controls the transmitting and receiving switching circuit to open the receiving circuit channel and close the transmitting circuit channel, and the echo signal is sent to the transmitting and receiving switching circuit and the receiving circuit in turn. The digital control processing chip collects the echo signals, and the collected echo signals are sequentially sent to the portable control terminal through the USB interface circuit, and the portable control terminal processes the collected echo signals to obtain ultrasonic images and display them come out.

便携式控制终端为超声仪供电的电压不超过5V、电流不超过1500mA,过流保护器限制便携式控制终端输入低电源模块的电压不超过500mA,数字电源能够输出3.3V、300mA以及1.2V、460mA两种适配电源,模拟电源能够输出3.3V、400mA的适配电源。The voltage of the portable control terminal to power the ultrasound instrument does not exceed 5V and the current does not exceed 1500mA. The overcurrent protector limits the voltage of the portable control terminal input to the low power module not to exceed 500mA. The digital power supply can output 3.3V, 300mA and 1.2V, 460mA. A kind of adaptable power supply, the analog power supply can output 3.3V, 400mA adaptable power supply.

由前述可知,超声仪都是采用便携式控制终端供电,超声仪中的低电源模块能够将便携式控制终端输入的电能转换为相适配的电能,因此能够满足超声仪小型化需求。It can be seen from the foregoing that the ultrasound instruments are powered by portable control terminals, and the low power module in the ultrasound instruments can convert the electric energy input by the portable control terminal into suitable electric energy, so it can meet the miniaturization requirements of the ultrasound instruments.

根据扫描的需要通过便携式控制终端向超声仪发出进行扫描的指令,凸阵扫描用于对人体腹部进行扫描,扫描用于对人体浅表部位进行扫描。发射波束控制模块通过发射电路控制发射接收切换电路打开发射电路通道和关闭接收电路通道,发射波束控制模块控制超声换能器发出扫描波束,超声换能器将获得的回波信号发送给发射接收复用电路。接收控制模块检测到发射接收复用电路有回波信号时,接收控制模块控制发射接收切换电路打开接收电路通道和关闭发射电路通道,回波信号依次通过发射接收切换电路和接收电路发送到数据处理模块,数据处理模块对回波信号进行采集,采集的回波信号依次通过接口控制模块和USB接口电路发送到便携式控制终端,便携式控制终端对采集的回波信号进行处理获得超声图像并将其显示出来。According to scanning requirements, a command for scanning is sent to the ultrasound machine through the portable control terminal, the convex array scanning is used to scan the abdomen of the human body, and the scanning is used to scan the superficial parts of the human body. The transmitting beam control module controls the transmitting and receiving switching circuit to open the transmitting circuit channel and close the receiving circuit channel through the transmitting circuit. The transmitting beam control module controls the ultrasonic transducer to send out a scanning beam, and the ultrasonic transducer sends the obtained echo signal to the transmitting and receiving complex. use circuit. When the receiving control module detects that there is an echo signal in the transmitting and receiving multiplexing circuit, the receiving control module controls the transmitting and receiving switching circuit to open the receiving circuit channel and close the transmitting circuit channel, and the echo signal is sent to the data processing through the transmitting and receiving switching circuit and the receiving circuit in turn. module, the data processing module collects the echo signals, and the collected echo signals are sequentially sent to the portable control terminal through the interface control module and the USB interface circuit, and the portable control terminal processes the collected echo signals to obtain ultrasonic images and display them come out.

便携式控制终端向超声仪发出进行扫描的指令后,发射波束控制模块控制超声换能器发出扫描波束,接口控制模块控制发射波束控制模块和接收控制模块交替运行,从而使该超声仪能够实现超声扫描功能。After the portable control terminal sends an instruction to scan to the ultrasound machine, the transmit beam control module controls the ultrasound transducer to send out scanning beams, and the interface control module controls the transmit beam control module and the receive control module to operate alternately, so that the ultrasound machine can realize ultrasound scanning. Function.

示例四:Example four:

利用多动态参数处理获得心脏射血分数的方法如下:The method of obtaining cardiac ejection fraction using multi-dynamic parameter processing is as follows:

1、采用示例一、二、三所提供的,同时具备超声信号采集功能、肌电信号采集功能的采集装置,从同一机体上采集到超声信号、肌电信号,并将采集到的信号同步显示在显示装置上。1. Using the acquisition device provided in Examples 1, 2, and 3, which has both ultrasonic signal acquisition functions and EMG signal acquisition functions, the ultrasonic signals and EMG signals are collected from the same body, and the collected signals are displayed synchronously on the display device.

这里的同一机体,是指人体或者是人体心脏。超声信号信息是M超心动图,肌电信息是心电信号,表现在心电QRS波心电图。由于心脏的跳动,是以心电激发的心脏进行收缩运动,因此,一个心电信息,对应一个心脏的周期跳动,又因此,心电信号与心脏周期跳动的对应同步的,这里的对应同步并非指同时进行,而是指相应地跟随进行。The same organism here refers to the human body or the human heart. The ultrasound signal information is M echocardiography, and the electromyographic information is an electrocardiogram signal, which is shown in the electrocardiogram QRS wave electrocardiogram. Since the beating of the heart is the contraction movement of the heart stimulated by the heart, therefore, one ECG information corresponds to the periodic beating of the heart, and therefore, the corresponding synchronization between the ECG signal and the cardiac cycle beating, the corresponding synchronization here is not It means to proceed simultaneously, but to follow accordingly.

2、上面步骤一中所述的同步显示,其方式为:将采集到的心电QRS波,与心电同步发生的心脏形态变化的M超声影像,分布到同一时间轴上并对齐到同一起始时间点。将采集到超声信号、肌电信号同步显示在显示装置上;使时实投射到显示装置上的超声信号、肌电信号的显示时间差,等于采集到信号的采集时间差。2. The synchronous display described in the above step 1 is as follows: the collected ECG QRS waves and the M-ultrasound images of the cardiac morphological changes that occur synchronously with the ECG are distributed on the same time axis and aligned together. start time point. The collected ultrasonic signals and EMG signals are displayed on the display device synchronously; the display time difference of the ultrasonic signals and EMG signals projected to the display device in real time is equal to the collection time difference of the collected signals.

具体如下:由于采集装置是采用同时具备超声信号采集功能、肌电信号采集功能的采集装置在同一机体上完成,而且是显示在同一显示装置(显示器)上,因此,采集装置的采集部位(参考图1,比如单阵元超声探头2、拾音器4,心电传感器/心电电极3)获得上述信号,由于人体的心跳是由心电激发,因此,在一个心跳周期内(心脏收缩初期到心脏舒张未期),先是产生心电信号,接下来产生心脏形态变化,因此采集装置的采集部位采集到的心电信号和心脏形态变化有一个时间差(因为先是有心电,随后才有心动/心脏形态变化),这个时间差要准确地反应在显示装置上,因此这个时间差要通过方法计算,并且相应如实地反应,使时实投射到显示装置上的超声信号、肌电信号的显示时间差,等于采集到信号的采集时间差。The details are as follows: Since the acquisition device is completed on the same body by using the acquisition device with both the ultrasonic signal acquisition function and the electromyographic signal acquisition function, and is displayed on the same display device (display), therefore, the acquisition part of the acquisition device (refer to Fig. 1, for example, single-array element ultrasonic probe 2, pickup 4, ECG sensor/electrode electrode 3) obtain the above-mentioned signals, because the human heartbeat is excited by ECG, therefore, within a heartbeat cycle (from the early stage of cardiac systole to the Before diastole), the ECG signal is generated first, and then the cardiac morphological change is generated. Therefore, there is a time difference between the ECG signal collected by the acquisition part of the acquisition device and the cardiac morphological change (because there is ECG first, and then there is cardiac/heart morphology. Change), this time difference should be accurately reflected on the display device, so this time difference should be calculated by the method, and correspondingly and faithfully respond, so that the real-time projection of the ultrasonic signal and the EMG signal on the display device The display time difference is equal to the collected data. The acquisition time difference of the signal.

3、在M超声影像中,在心电QRS波中的Q波、R波、S波之一产生后的第一特定时长后的时间点,获得M超声影像的第一纵向像素列,并在第一纵向像素列中找出左心室前壁内膜与左心室后壁内膜之间的间距的最小值。在M超声影像中,在心电QRS波中的Q波、R波、S波之一产生后的第二特定时长后的时间点,获得M超声影像的第一纵向像素列,并在第二纵向像素列中找出左心室前壁内膜与左心室后壁内膜之间的间距的最大值。3. In the M ultrasound image, at a time point after the first specific time period after one of the Q wave, R wave, and S wave in the QRS wave of the ECG is generated, the first longitudinal pixel column of the M ultrasound image is obtained, and in the first Find the minimum value of the distance between the intima of the anterior wall of the left ventricle and the intima of the posterior wall of the left ventricle in a longitudinal pixel column. In the M ultrasound image, at a time point after a second specific time period after one of the Q wave, R wave, and S wave in the QRS wave of the electrocardiogram is generated, the first longitudinal pixel column of the M ultrasound image is obtained, and the second longitudinal pixel column is obtained. Find the maximum value of the distance between the intima of the anterior wall of the left ventricle and the intima of the posterior wall of the left ventricle in the pixel column.

第一特定时长与第二特定时长的计算方法为:分析若干个经二值化处理的M超声影像,标出左心室前壁内膜与左心室后壁内膜之间的间距的最小值出现的时间,并计算出在Q波、R波、S波之一出现的时间与最小值出现的时间的时差,得到第一特定时长;并计算出在Q波、R波、S波之一出现的时间与最大值出现的时间的时差,得到第二特定时长。这里要考虑到不同的机体,心电周期可能不一样,以及一个周期内,各个波长略有区别。心电具有QRS波群,QRS波群内由Q波、R波、S波组成,例如,某一机体的心脏情况如下:在心电R波发生,经过第一特定时长0.40s后,心脏进入收缩期未端,达到最小容积,为快速射血期;在R波经过发生,并经过第二特定时长0.80s后,心脏进入舒张期末端,达到最大容积。这里是以R波的发生时间作为起算点,因为R波的特征点最为明显,也就是波峰值最大,最容易被识别。当然,也可以按其它Q波、S波、T波、P波作为时间起算点,这些波峰都是在一个心跳周期上,每一个心跳周期都有这些波,因此,以哪一个波峰作起算点并不重要。当以R波作为起算点:第一特定时长0.40s后,心脏进入收缩期未端,达到最小容积;并经过第二特定时长0.80s后,心脏进入舒张期末端,达到最大容积;以Q波作为起算点:Q波发生,经第一特定时长0.36s后,心脏进入收缩期未端,达到最小容积;并经过第二特定时长0.76s后,心脏进入舒张期末端,达到最大容积。最小容积和最大容积的影像将被超声捕捉,产生M超心动图。The calculation method of the first specific time period and the second specific time period is: analyze several M ultrasound images processed by binarization, and mark the occurrence of the minimum value of the distance between the intima of the anterior wall of the left ventricle and the intima of the posterior wall of the left ventricle. time, and calculate the time difference between the time when one of the Q wave, R wave, and S wave appears and the time when the minimum value appears, and obtain the first specific duration; and calculate the time when one of the Q wave, R wave, and S wave appears. The time difference between the time when the maximum value occurs and the time when the maximum value occurs, the second specific duration is obtained. It is necessary to take into account that different organisms may have different ECG cycles, and within a cycle, each wavelength is slightly different. ECG has QRS complex, which is composed of Q wave, R wave and S wave. For example, the heart of a certain body is as follows: after the occurrence of ECG R wave, after the first specific time period of 0.40s, the heart enters contraction At the end of the period, the minimum volume is reached, which is the rapid ejection period; after the R wave occurs, and after a second specific period of 0.80s, the heart enters the end of the diastolic period and reaches the maximum volume. Here, the occurrence time of the R wave is used as the starting point, because the characteristic point of the R wave is the most obvious, that is, the peak value of the wave is the largest, and it is easiest to identify. Of course, other Q waves, S waves, T waves, and P waves can also be used as the starting point. These peaks are all in one heartbeat cycle, and each heartbeat cycle has these waves. Therefore, which wave peak is used as the starting point it is not important. When the R wave is used as the starting point: after the first specific period of 0.40s, the heart enters the end of systole and reaches the minimum volume; and after the second specific period of 0.80s, the heart enters the end of diastole and reaches the maximum volume; the Q wave As a starting point: after the Q wave occurs, the heart enters the end of systole and reaches the minimum volume after the first specific period of 0.36s; and after the second specific period of 0.76s, the heart enters the end of diastole and reaches the maximum volume. The images of the smallest and largest volumes will be captured by ultrasound, producing an M echocardiogram.

通过所述的最小值与最大值,通过以下计算公式:Through the stated minimum and maximum values, through the following calculation formula:

EF=(EDV-ES)*100%计算出心脏射血分数,其中EF为心脏射血分数,EDV是心脏左心室前后壁内膜最大距离时心脏左心室的最大容积;ES心脏左心室前后壁内膜最小距离时心脏左心室的最小容积;EF=(EDV-ES)*100% to calculate the cardiac ejection fraction, where EF is the cardiac ejection fraction, EDV is the maximum volume of the left ventricle at the maximum distance between the anterior and posterior walls of the left ventricle of the heart; ES The minimum volume of the left ventricle of the heart at the minimum intimal distance;

其中,通过心脏左心室前后壁内膜最小距离,计算出心脏左心室的最大容积;通过心脏左心室前后壁内膜最大距离,计算出心脏左心室最大容积。Among them, the maximum volume of the left ventricle of the heart is calculated through the minimum distance between the anterior and posterior intima of the left ventricle of the heart;

本发明的M超声影像:M超声影像就是由若干密集的像素点构成的图像,把这些像素点矩阵排列,分为平行于时间轴的横向像素行,垂直于时间轴的纵向像素行组成,第一纵向像素列、第一纵向像素列均是很多纵向像素列中的一列。M-ultrasound image of the present invention: M-ultrasound image is an image composed of a number of dense pixel points. These pixel points are arranged in a matrix and divided into horizontal pixel rows parallel to the time axis and vertical pixel rows perpendicular to the time axis. Both a vertical pixel row and the first vertical pixel row are one of many vertical pixel rows.

在这个基础上,为了在一帧M超声影像中,找出左心室前壁内膜与左心室后壁内膜之间的间距的最小值与最大值,可以借助于心电QRS波群时间,与心脏收缩期未端及心脏舒张期未端的关系。On this basis, in order to find the minimum and maximum values of the distance between the left ventricular anterior intima and the left ventricular posterior intima in a frame of M ultrasound images, the ECG QRS complex time can be used to Relationship with the end of systole and end of diastole.

在借助这种关系时,满足于:各信号时实投射到显示装置上,并使投射到显示装置上各信号之间的时间差,等于采集到各信号的采集时间差;具体地,心电波群对应在一帧M超声影像中,并使心电和超声影像投射到显示装置时间差,等于心电信号和超声信号被传达到采集头上的采集时间差。例如:心电R波信号从机体产生,在第0s被示例一中的肌电采集电极采集到,而在R波信号从机体产生,经过第一特定时长0.40s后心脏进入收缩期未端,也就是说单阵元超声探头0.40s采集到心脏进入收缩期未端这一影像,从而超声影像与R波信号被采集到的时间,就有0.40s的采集时间差,也就是说采集时间差是0.40s。而自肌电采集电极采集到R波信号到投射到显示器上需要0.5s,自单阵元超声探头采集到采集心脏影像至影像被投射到显示器上只需要0.37s,若是将心电R波信号与超声影像信号直接投射,就会造成在显示器上看到的R波信号产生0.37s后心脏就进入收缩期未端。因此,这一时差是错误的,必须要把机体上心电与影像的实际时差反应到显示器上,以免计算错误。When relying on this relationship, it is satisfied that: each signal is projected on the display device in real time, and the time difference between the signals projected on the display device is equal to the acquisition time difference of the acquired signals; In one frame of M ultrasound image, the time difference between the electrocardiogram and the ultrasound image projected to the display device is equal to the acquisition time difference between the electrocardiogram signal and the ultrasound signal being transmitted to the acquisition head. For example, the ECG R-wave signal is generated from the body, and is collected by the EMG acquisition electrode in Example 1 at 0s, and when the R-wave signal is generated from the body, the heart enters the end of systole after the first specific time period of 0.40s. That is to say, the single-array element ultrasound probe collects the image of the heart entering the end of systole in 0.40s, so the time when the ultrasound image and the R-wave signal are collected, there is a 0.40s acquisition time difference, that is to say, the acquisition time difference is 0.40 s. However, it takes 0.5s to collect the R-wave signal from the EMG acquisition electrode and project it to the display. It only takes 0.37s to collect the cardiac image from the single-element ultrasound probe to the image is projected on the display. If the ECG R-wave signal is Direct projection with the ultrasound image signal will cause the R-wave signal seen on the monitor to generate 0.37s after the heart enters the end of systole. Therefore, this time difference is wrong, and the actual time difference between the ECG and the image on the body must be reflected on the monitor to avoid calculation errors.

在处理了采集时差与显示时差后,可以严格地按心电心电QRS波对应到超声影像中,寻找心脏进入舒张期末端(最大容积,或者叫做最大值),例如,在R波发生第一特定时长0.40后,对应到M超声影像上的相应这一列像素(第一纵向像素列),就是心脏的收缩期未端,达到最小容积、最小值。在R波发生第一特定时长0.80s后,对应到M超声影像上的相应这一列像素(第二纵向像素列),就是心脏的舒张期末端,也就是最大容积、最大值。After processing the acquisition time difference and the display time difference, the QRS wave of the ECG can be strictly mapped to the ultrasound image to find the end of the heart entering the diastolic phase (maximum volume, or the maximum value), for example, when the R wave occurs first After a specific time period of 0.40, the corresponding row of pixels (the first longitudinal pixel row) on the M ultrasound image is the end of the systole of the heart, reaching the minimum volume and the minimum value. After the R wave occurs for a first specific duration of 0.80s, the corresponding row of pixels (the second longitudinal pixel row) on the M ultrasound image is the end of the diastolic phase of the heart, that is, the maximum volume and the maximum value.

示例五:Example five:

示例四中提到的:把机体上心电与影像的实际时差反应到显示器上,以免计算错误,方法如下:As mentioned in Example 4: The actual time difference between the ECG and the image on the body is reflected on the display to avoid calculation errors. The method is as follows:

采用示例一、二、三所提供的,同时具备超声信号采集功能、肌电信号采集功能、音频信号采集功能的三项中至少两项采集功能的采集装置,从同一机体上采集到超声信号、肌电信号、音频信号中的至少两种信号,并将采集到的信号同步显示在显示装置上。Using the acquisition devices provided in Examples 1, 2, and 3, which simultaneously have at least two acquisition functions among the three functions of ultrasonic signal acquisition, EMG signal acquisition, and audio signal acquisition, the ultrasonic signals, At least two kinds of signals in the electromyography signal and the audio signal, and the collected signals are displayed on the display device synchronously.

显示装置上设置有持续时间轴和实时状态轴。本发明所指的时间轴,是投射到显示装置上的横向轴;实时状态轴也可以称为变化状态轴,实时状态轴为投入到显示装置上的纵向轴,时间轴和变化状态轴体现在显示装置上,可以看到信号的变化状态与时间的关系。A continuous time axis and a real-time state axis are provided on the display device. The time axis referred to in the present invention is the horizontal axis projected on the display device; the real-time state axis can also be called the changing state axis, the real-time state axis is the vertical axis that is put on the display device, and the time axis and the changing state axis are embodied in On the display device, you can see the relationship between the changing state of the signal and time.

在此处的同步显示为:各信号时实投射到显示装置上,并使投射到显示装置上各信号之间的时间差,等于采集到各信号的采集时间差。The synchronous display here is as follows: each signal is projected onto the display device in real time, and the time difference between the signals projected onto the display device is equal to the acquisition time difference of the acquired signals.

由于采集到超声信号、肌电信号、音频信号中,至少一个信号受处理电路影响使显示时间较其余信号滞后;因此受处理电路影响的信号的投放到显示装置上的时间,滞后于其余信号,具体地说,各种电子原器件的电路原因,以及软件对收集到的信息进行处理原因,导致信号采集致信号呈现有一个时间差,而且不同的信息源具有不同的时间差,例如:心跳声通过电路及软件处理即可非常快,超声图像也可以较快,但是心电信号从采集到呈现则相对较慢,约慢0.125S。因此,为了使呈现出的信息的一致性,需要对呈现的信息进行调整。也就是所述的“同步”。Due to the collected ultrasonic signal, EMG signal, and audio signal, at least one signal is affected by the processing circuit, so that the display time lags behind the rest of the signals; therefore, the time when the signal affected by the processing circuit is put on the display device lags behind the rest of the signals. Specifically, due to the circuit reasons of various electronic original devices and the reason why the software processes the collected information, there is a time difference between the signal acquisition and the signal presentation, and different information sources have different time differences, for example: the sound of the heartbeat passes through the circuit And software processing can be very fast, ultrasound images can also be fast, but the ECG signal is relatively slow from acquisition to presentation, about 0.125S. Therefore, in order to make the presented information consistent, the presented information needs to be adjusted. This is the so-called "synchronization".

同一电路以及同一软件对信号的处理所带来的延时时间是一致的,因此我们可以根据电路以及软件的特性,推算出电信号处理延迟的时间。更好的是通过软件与电路实际进行测试,测试得到软件和电路对该信号处理的所需时间。我们把这个时间记录下来。超声信号、心跳声音信号以及心电信号,三者处理步骤相同,并分别具有不同的所需处理时间。我们记录下超声信号,心跳声音,信号以及心电信号,三者各自所需的处理时间,得到心电信号处理时所需的时长最长,因此我们在呈现三个信号的时候,当心跳声音超声信号处理完毕之后,我们不立即进行呈现,而是延迟等待,等待心电信号的处理完成,等待的时间为提前记录下来的心电信号与其余两者(超声信号、声音信号)的延迟差值,当处理完毕声音信号以及超声图像信号之后,等待上述延迟差值,即可将声音信号以及超声信号呈现;在同一时刻,心电信号也处理完毕,也立即进行呈现;从而呈现出来的超声信号心,电信号以及声音信号为同步对齐时间(即采集状态)。The delay time brought by the same circuit and the same software for signal processing is consistent, so we can calculate the delay time of electrical signal processing according to the characteristics of the circuit and software. Even better is to actually test the software and the circuit to get the time required by the software and the circuit to process the signal. We record this time. The ultrasonic signal, the heartbeat sound signal and the electrocardiogram signal have the same processing steps and have different required processing times. We recorded the ultrasound signal, the heartbeat sound, the signal and the ECG signal. The processing time required for each of the three is the longest time required to process the ECG signal. Therefore, when we present the three signals, when the heartbeat sound After the ultrasound signal is processed, we do not present it immediately, but delay and wait until the processing of the ECG signal is completed. The waiting time is the delay difference between the ECG signal recorded in advance and the other two (ultrasound signal, sound signal). After the sound signal and the ultrasound image signal are processed, the sound signal and the ultrasound signal can be presented after waiting for the above delay difference; at the same time, the ECG signal is also processed and presented immediately; thus the presented ultrasound The signal heart, the electrical signal and the sound signal are synchronized and aligned in time (ie, the acquisition state).

同步显示具体方法为,参考图6:The specific method of synchronous display is, refer to Figure 6:

S1:先获得超声信号、肌电信号、音频信号各自处理所需时长,例如:超声信号处理时长为0.5s、肌电信号0.625s、音频信号0.5s;得到其中的最大时长为肌电信号0.625s,然后将其余信号处理的时长与该最大时长对比,用最大时长0.625减去音频信号(或超声)0.5s,获得对比时长0.125s;所述的处理所需时长,是从采集到信号的采集时间,直至信号显示在显示装置上这一过程的所需时间,例如:心电R波信号从机体产生,在第0s被示例一中的肌电采集电极采集到,到投射到显示器上需要0.625s。S1: First obtain the time required for the respective processing of the ultrasonic signal, the EMG signal, and the audio signal, for example: the ultrasonic signal processing time is 0.5s, the EMG signal is 0.625s, and the audio signal is 0.5s; the maximum time obtained is the EMG signal 0.625 s, and then compare the duration of the remaining signal processing with the maximum duration, subtract 0.5s of the audio signal (or ultrasound) from the maximum duration of 0.625, and obtain a comparison duration of 0.125s; the duration required for the processing is from the acquisition to the signal Acquisition time until the signal is displayed on the display device. For example, the ECG R-wave signal is generated from the body, and is collected by the EMG acquisition electrode in Example 1 at 0s, and it needs to be projected on the display. 0.625s.

S2:将处理所需时长为最大时长的信号处理完成后,立即显示;将其余信号在处理完成,并经过了对比时长后,立即显示。也就是说,将心电信号处理完成后,立即投到显示器上显示,投放到显示器上的延时就是0.625s,将其余信号在处理完成,并经过了对比时长0.125s后,立即显示,投放到显示器上的延时就是0.625s,因此投入到显示器上的时差(时延)相等。使显示器上看到的心电和影像的时差情况完成是真实的时差情况。S2: After the processing of the signal with the maximum duration required for processing is completed, it is displayed immediately; the remaining signals are displayed immediately after the processing is completed and the comparison time has passed. That is to say, after the ECG signal is processed, it will be displayed on the display immediately, and the delay of putting it on the display is 0.625s. After the processing of the rest of the signals is completed, and the comparison time has passed for 0.125s, it will be displayed immediately and put on the display. The delay to the display is 0.625s, so the time difference (delay) put into the display is equal. Make the time difference situation of the ECG and image seen on the monitor complete to be the real time difference situation.

超声信号为心脏M超影像信号;所述的肌电信号为心电QRS波信号、所述的音频信号为心音。The ultrasound signal is a cardiac M-ultrasound image signal; the electromyographic signal is an electrocardiographic QRS wave signal, and the audio signal is a heart sound.

示例六:Example six:

在示例四中所需的通过影像像素,计算得到心脏最小容积和最大容积的计算方法,可以参考以下本示例。For the calculation method of calculating the minimum volume and the maximum volume of the heart through the image pixels required in Example 4, please refer to the following example.

在心脏射血分数分析时,需要知道心脏收缩时心脏最小容积,以及心脏扩张时心脏最大容积。In the analysis of cardiac ejection fraction, it is necessary to know the minimum volume of the heart during systole and the maximum volume of the heart during expansion.

当采用设备软件自动识别的时候,由于设备软件不能很好地通过超声图像准确的识别心脏最大容积与最小容积,因此我们给设备软件注入心跳声音以及心电波形图,当设备软件获得心电波形图(以及心跳声音)后,从连续变化的心电波形图上,对应到对应的连续变化的超声图上,去寻找最恰当心脏前后壁距离的断面形状。例如:When the device software is used for automatic identification, since the device software cannot accurately identify the maximum volume and the minimum volume of the heart through the ultrasound image, we inject the heartbeat sound and the ECG waveform into the device software. When the device software obtains the ECG waveform After the image (and the heartbeat sound), from the continuously changing ECG waveform, corresponding to the corresponding continuously changing ultrasound image, to find the most appropriate cross-sectional shape of the distance between the anterior and posterior walls of the heart. E.g:

可以在心电R波后的0.04秒,对应到连续变化的超声图上,此断面为心脏左心室前后壁的最小值,也就是通过心电图可以明确,心脏前后壁距离的最小值一定是在该断面,由于该断面已经划定了一个极小的范围区域,因此可以通过图像识别在该极小的范围区域内极容易找出前后壁的距离。图像识别的方法可以多种方法:例如中国专利公开的CN201310125145.X提供的色块识别方法及装置,通过对需要识别的图像进行边缘检测,提取需要识别的图像中色块的轮廓来确定色块的形状,根据提取到的色块的轮廓计算色块的质心坐标来获取色块的位置,选取色块内的一个点所在位置的颜色来确定色块的颜色。因此其能够同时识别色块的形状、位置及颜色,从而能够更加全面的提取色块的信息。图像识别的方法可以多种方法:例如灰度识别。It can be 0.04 seconds after the ECG R wave, which corresponds to the continuously changing ultrasound image. This section is the minimum value of the anterior and posterior walls of the left ventricle of the heart. , since the section has delineated a very small area, it is very easy to find the distance between the front and rear walls in this very small area through image recognition. The method of image recognition can be various methods: for example, the color block identification method and device provided by CN201310125145.X disclosed by Chinese patent, by performing edge detection on the image to be recognized, extracting the contour of the color block in the image to be recognized to determine the color block The shape of the color block is calculated according to the contour of the extracted color block to obtain the position of the color block, and the color of a point in the color block is selected to determine the color of the color block. Therefore, it can identify the shape, position and color of the color block at the same time, so that the information of the color block can be extracted more comprehensively. The method of image recognition can be various methods: such as grayscale recognition.

图像识别的方法可以多种方法,例如可以采用中国专利CN202010409334.X一种肺部超声图像识别方法和系统中的部分方法。The method of image recognition can be various methods, for example, Chinese patent CN202010409334.X can be used for a lung ultrasound image recognition method and some methods in the system.

对有效区域图像分别进行灰度化和归一化处理后得到归一化灰度图像。A normalized grayscale image is obtained after graying and normalizing the image of the effective area respectively.

采用如下公式对有效区域图像进行灰度化:Use the following formula to grayscale the image in the effective area:

Gray=R*0.299+G*0.587+B*0.114,其中R、G、B分别为红色,绿色和蓝色分量。Gray=R*0.299+G*0.587+B*0.114, where R, G, and B are red, green and blue components, respectively.

将归一化灰度图像分别缩放成统一尺寸并形成待识别图像。The normalized grayscale images are respectively scaled to a uniform size and an image to be recognized is formed.

对归一化灰度图像进行缩放,缩放成统一尺寸例如大小为256*256的待测图像,优选的,采用双线性插值、三次样条插值或者Lanczos插值等方法对进行缩放。The normalized grayscale image is scaled to a uniform size, for example, an image to be tested with a size of 256*256. Preferably, bilinear interpolation, cubic spline interpolation, or Lanczos interpolation is used for scaling.

采用图形识别的方法找出了左心室前后壁的间距最小值,即可获得心脏收缩到最小时心脏容积,并用同样的方法找出左心室前后壁的最大值既可获得心脏扩张到最大时心脏的容积。在带入射血分数分析公式,即可得到射血分数。The minimum value of the distance between the anterior and posterior walls of the left ventricle can be found by the method of graphic recognition, and the heart volume can be obtained when the heart contracts to the minimum. volume. The ejection fraction can be obtained by taking the injected blood fraction analysis formula.

示例七:Example seven:

在示例四、六中所需的通过影像像素,计算得到心脏最小容积和最大容积的计算方法,可以参考以下本示例。For the calculation method of calculating the minimum volume and maximum volume of the heart through the image pixels required in Examples 4 and 6, you can refer to the following example.

一、要计算心脏最小容积和最大容积,需要在超声心动图上确定左室隔内膜边界与左室后壁内膜边界的方法。如下:1. To calculate the minimum and maximum cardiac volumes, a method for determining the intimal boundary of the left ventricular septum and the intimal boundary of the posterior wall of the left ventricle is required on echocardiography. as follows:

S1:从超声心动图上设置虚拟中心线,虚拟中心线大致位于在上边界至下边界相同距离;S1: Set a virtual centerline from the echocardiogram, and the virtual centerline is approximately at the same distance from the upper boundary to the lower boundary;

从虚拟中心线处,将超声心动图分别为:具有二尖瓣图像和左室隔内膜图像的超声心动图上图;以及具有左室后壁内膜边界的超声心动图下图;From the virtual centerline, the echocardiograms are: upper echocardiogram with mitral valve image and left ventricular septal endometrial image; and echocardiogram lower image with left ventricular posterior wall intima border;

S2:对超声心动图上图进行处理,获得左室隔膜边界。对超声心动图下图进行处理,获得左室后壁内膜边界。S2: The upper image of the echocardiogram is processed to obtain the border of the left ventricular septum. The echocardiogram below was processed to obtain the intimal border of the posterior left ventricular wall.

二、其中,对超声心动图上图进行处理,获得左室隔膜边界的方法是:2. Among them, the method of processing the upper image of the echocardiogram to obtain the boundary of the left ventricular septum is as follows:

S01:在具有二尖瓣图像和左室隔内膜图像的超声心动图上,确定左室隔内膜和二尖瓣的相邻区域的大致范围,方法为:S01: On an echocardiogram with images of the mitral valve and the intima of the left ventricular septum, determine the approximate extent of the intima of the left ventricle and the adjacent areas of the mitral valve by:

(1):在超声心动图上,以靠近二尖瓣一侧的连续边缘为超声心动图上边界,在上边界下方并距离上边界30个像素点处所在的像素行,设置为计算起点线:(1): On echocardiography, take the continuous edge close to the mitral valve side as the upper boundary of echocardiography, and set the pixel row below the upper boundary and 30 pixels away from the upper boundary as the calculation starting line :

(2):在计算起点线处,向下,统计平行于计算起点线的每一像素行中,黑色像素点所占百分比;(2): At the calculation starting point line, downward, count the percentage of black pixels in each pixel row parallel to the calculation starting point line;

(3):当获得的第一个至少具有35%黑色像素点的像素行,为大致范围的范围上边线;(3): When the first pixel row with at least 35% black pixels is obtained, it is the upper edge of the approximate range;

(4):按如下方法获取大致范围的范围下边线:(I)继续沿二尖瓣像素块域的范围上边线向下统计每一像素行中,黑色像素点所占百分比,当黑色像素点占所在像素行中比例最大时,所对应到的像素行是大致范围的范围下边线;(II)当获得多个像素行满足于上述条件(I)时,则最靠近范围上边线的第一个满足上述条件(I)的像素行,是大致范围的范围下边线。(4): Obtain the bottom line of the approximate range as follows: (1) Continue to count the percentage of black pixels in each pixel row along the top line of the mitral pixel block domain. When the proportion of the pixel row is the largest, the corresponding pixel row is the lower edge of the approximate range; (II) when a plurality of pixel rows are obtained that satisfy the above condition (I), then the first one closest to the upper edge of the range is obtained. A pixel row that satisfies the above condition (I) is the lower boundary line of the approximate range.

S02:在大致范围内,找到左室隔内膜和二尖瓣的相邻区域的像素块域,方法为,在大致范围内,由上边范围线向下边范围线逐行查找,并至少满足于如下查找条件:(I)在同一列像素点中,像素灰度值由上边范围线向下边范围线至少有十个像素点为递增;(II)查找到的第一个具有上述(I)特征的范围,为左室隔内膜和二尖瓣相邻区域像素块域。当满足于查找条件时,在查找到的左室隔内膜和二尖瓣相邻区域像素块域内,允许有且同时仅有以下情况之一,这种情况视为噪点:(I)有不多于2个像素点的灰度值相较于上一个像素点停止递增;(II)有1个像素点的灰度值相较于上一个像素点减少。S02: Within a rough range, find the pixel block domain of the adjacent regions of the left ventricular septum intima and the mitral valve, the method is: within the rough range, search line by line from the upper range line to the lower range line, and at least satisfy The search conditions are as follows: (I) In the same column of pixels, the gray value of the pixel increases by at least ten pixels from the upper range line to the lower range line; (II) The first one found has the above (I) characteristics The range is the pixel block domain of the left ventricular septal intima and the adjacent areas of the mitral valve. When the search conditions are satisfied, in the pixel block domain of the found adjacent regions of the left ventricular septum intima and the mitral valve, one and only one of the following situations is allowed, and this situation is regarded as noise: (I) There is no The gray value of more than 2 pixels stops increasing compared to the previous pixel; (II) the gray value of one pixel decreases compared to the previous pixel.

S03:将相邻区域的像素块域的灰度值设置为0;S03: Set the gray value of the pixel block domain of the adjacent area to 0;

S04:将包括有像素块域灰度值被设置为0的相邻区域的超声心动图进行二值化处理,获得相邻区域以及二尖瓣区域均被排除在左室隔内膜外的二值化超声心动图。S04: Perform binarization processing on the echocardiogram including the adjacent regions where the pixel block domain gray value is set to 0, and obtain the echocardiogram in which the adjacent region and the mitral valve region are both excluded from the left ventricular septal intima Valued echocardiography.

S05:在二值化超声心动图上划定感兴趣区域,感兴趣区域包括有全部的左室隔内膜边界图像;感兴趣区域的计算方法:在超声心动图上,以靠近二尖瓣一侧的连续边缘为超声心动图上边界,在上边界下方并距离上边界30个像素点处所在的像素行,设置为感兴趣区域的第一边界。按如下方法获取感兴趣区域第二边界:(I)继续感兴趣区域第一边界向下统计每一像素行中,黑色像素点所占百分比,当黑色像素点占所在像素行中比例最大时,所对应到的像素行是感兴趣区域第二边界;(II)当获得多个像素行满足于上述条件(I)时,则最靠近感兴趣区域第一边界的第一个满足上述条件(I)的像素行,是感兴趣区域第二边界。S05: Delineate the region of interest on the binarized echocardiogram, and the region of interest includes all the images of the left ventricular septal intima boundary; the calculation method of the region of interest: on the echocardiography, the region close to the mitral valve The continuous edge on the side is the upper boundary of the echocardiogram, and the pixel row below the upper boundary and 30 pixels away from the upper boundary is set as the first boundary of the region of interest. Obtain the second boundary of the region of interest as follows: (1) Continue to count down the first boundary of the region of interest and count down the percentage of black pixels in each pixel row. When the proportion of black pixels in the pixel row is the largest, The corresponding pixel row is the second boundary of the region of interest; (II) when a plurality of pixel rows are obtained that satisfies the above condition (I), the first one closest to the first boundary of the region of interest satisfies the above condition (I). ) is the second boundary of the region of interest.

在感兴趣区域第一边界与感兴趣区域第二边界之间,为感兴趣区域。The region of interest is between the first boundary of the region of interest and the second boundary of the region of interest.

S06:对感兴趣区域进行形态学开运算,使二值化后的超声心动图更加光滑;随后进行边缘检测,得到左室隔内膜边界;S06: Perform morphological opening operation on the region of interest to make the binarized echocardiogram smoother; then perform edge detection to obtain the left ventricular septal intima border;

S07:对得到的左室隔内膜边界进行闭运算,并使得到的左室隔内膜边界为连通域。也就是最后的左室隔内膜边界边界。S07: Perform a closing operation on the obtained left ventricular septal intima boundary, and make the obtained left ventricular septal intima boundary a connected domain. This is the final left ventricular septal endometrial border.

三、其中,对超声心动图下图进行处理,获得左室后壁内膜边界的方法是:3. Among them, the method for obtaining the intimal boundary of the posterior wall of the left ventricle by processing the following echocardiogram is as follows:

1:二值化超声图像;标定以靠近二尖瓣一侧的连续边缘为超声心动图上边界;上边界的相反侧的连续边缘为超声心动图下边界;1: Binarized ultrasound image; the continuous edge on the side close to the mitral valve is the upper boundary of echocardiography; the continuous edge on the opposite side of the upper boundary is the lower boundary of echocardiography;

从超声心动图上,在上边界至下边界相同距离为虚拟中线,在虚拟中线处开始,向下边界方向,以像素列为单位,统计每一列第一次出现白像素点的所在行位置;From the echocardiogram, the same distance from the upper boundary to the lower boundary is the virtual midline, starting at the virtual midline, and going down the boundary direction, in units of pixel columns, and counting the row position of the first white pixel in each column;

2:统计得到的数据中,第一次出现白像素点所在行,距离上边界超过45个像素点的,所在列为数据错误列;2: In the statistical data, if the row where the white pixel is located for the first time, and the distance from the upper boundary is more than 45 pixels, the column is the data error column;

3:用以下方法纠正所在列数据错误:3: Use the following methods to correct the data error in the column:

(1)将相邻的具有错误数据的列合并为一个错误区间;(2)将错误区间左侧相邻的正确数据列所在的第一次出现白像素点所在行设置为第一参照点,将错误区间右侧相邻的正确数据列所在的第一次出现白像素点所在行设置为第二参照点;直线连接第一参照点与第二参照点,直线即为错误区间的左室后壁内膜边界。(1) Merge adjacent columns with wrong data into one error interval; (2) Set the row where the white pixel point first appears where the adjacent correct data column on the left side of the error interval is located as the first reference point, Set the row of the first white pixel point where the correct data column adjacent to the right side of the error interval is located is set as the second reference point; a straight line connects the first reference point and the second reference point, and the straight line is the left ventricular posterior of the error interval. Intima border.

4:进行形态学开运算,使二值化后的超声心动图更加光滑;随后进行边缘检测,得到左室后壁内膜边界。4: Perform morphological opening operation to make the binarized echocardiogram smoother; then perform edge detection to obtain the intimal boundary of the posterior wall of the left ventricle.

5:对得到的左室后壁内膜边界进行闭运算,并使得到的左室后壁内膜边界为连通域。也就是左室后壁内膜边界。5: Perform a closed operation on the obtained posterior intima boundary of the left ventricle, and make the obtained posterior intima boundary of the left ventricle a connected domain. This is the intimal border of the posterior wall of the left ventricle.

获得左心室前壁内膜与左心室后壁内膜之间的间距的最小值与最大值后,通过以下计算公式:EF=(EDV-ES)*100%计算出心脏射血分数,其中EF为心脏射血分数,EDV是心脏左心室前后壁内膜最大距离时心脏左心室的最大容积;ES心脏左心室前后壁内膜最小距离时心脏左心室的最小容积;After obtaining the minimum and maximum values of the distance between the intima of the anterior wall of the left ventricle and the intima of the posterior wall of the left ventricle, the cardiac ejection fraction is calculated by the following formula: EF=(EDV-ES)*100%, where EF is the cardiac ejection fraction, EDV is the maximum volume of the left ventricle when the distance between the anterior and posterior intima of the left ventricle is the largest; ES is the smallest volume of the left ventricle when the distance between the anterior and posterior intima of the left ventricle is the smallest;

其中,通过心脏左心室前后壁内膜最小距离,计算出心脏左心室的最大容积;通过心脏左心室前后壁内膜最大距离,计算出心脏左心室最大容积。Among them, the maximum volume of the left ventricle of the heart is calculated through the minimum distance between the anterior and posterior intima of the left ventricle of the heart;

以上为实施本发明列举的各个实施例。在上述实施例中,对各个实施例的描述都各有侧重,某个实施例中没有详述或记载的部分,可以参见其它实施例的相关描述。The above are the various embodiments enumerated for implementing the present invention. In the foregoing embodiments, the description of each embodiment has its own emphasis. For parts that are not described or described in detail in a certain embodiment, reference may be made to the relevant descriptions of other embodiments.

以上所述实施例仅用以说明本发明的技术方案,而非对其限制;尽管参照前述实施例对本发明进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本发明各实施例技术方案的精神和范围,均应包含在本发明的保护范围之内。The above-mentioned embodiments are only used to illustrate the technical solutions of the present invention, but not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: it can still be used for the foregoing implementations. The technical solutions described in the examples are modified, or some technical features thereof are equivalently replaced; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present invention, and should be included in the within the protection scope of the present invention.

以上,仅为本发明的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,可轻易想到各种等效的修改或替换,这些修改或替换都应涵盖在本发明的保护范围之内。因此,本发明的保护范围应以权利要求的保护范围为准。The above are only specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art can easily think of various equivalent modifications or changes within the technical scope disclosed by the present invention. Replacement, these modifications or replacements should all be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention should be subject to the protection scope of the claims.

Claims (10)

1. A method for collecting multi-dynamic parameter processing of an organism is characterized in that an acquisition device which has at least two acquisition functions of an ultrasonic signal acquisition function, an electromyographic signal acquisition function and an audio signal acquisition function at the same time is adopted to acquire at least two signals of the ultrasonic signal, the electromyographic signal and the audio signal from the same organism and synchronously display the acquired signals on a display device; the synchronization is that all the signals are projected on the display device in real time, and the time difference between all the signals projected on the display device is equal to the acquisition time difference of all the signals.
2. The method for processing the collected multiple dynamic parameters of the machine body according to claim 1, wherein the synchronous display specifically comprises:
s1, acquiring the time length required by the respective processing of the ultrasonic signal, the electromyographic signal and the audio signal; obtaining the maximum duration, and then comparing the duration of the rest signal processing with the maximum duration to obtain the comparison duration; the time length required by the processing is the time required from the acquisition of the signals to the display of the signals on the display device.
S2, immediately displaying the signal with the time length required by processing as the maximum time length after the signal processing is finished;
and (4) finishing processing the rest signals, and immediately displaying after the contrast time.
3. The method for collecting processing of multiple dynamic parameters of human body according to claim 1, wherein said ultrasound signal is heart M ultrasound image signal; the electromyographic signal is an electrocardio QRS wave signal, and the audio signal is a heart sound.
4. The method of claim 3, wherein said ECG QRS wave signal has a maximum duration; the comparison duration between the duration required by processing the electrocardio QRS wave signals and the duration of the rest signal processing is specifically as follows: 0.125S.
5. A method for obtaining the cardiac ejection fraction by utilizing multi-dynamic parameter processing is characterized in that,
the method comprises the steps that electrocardio QRS waves which are continuously collected from the same organism in the same time period and M ultrasonic images of heart form changes which synchronously occur with electrocardio are distributed on the same time axis and aligned to the same initial time point;
in the M ultrasonic image, obtaining a first longitudinal pixel array of the M ultrasonic image at a time point after a first specific time length after one of Q wave, R wave and S wave in the electrocardio QRS wave is generated, and finding out the minimum value of the distance between the inner membrane of the front wall of the left ventricle and the inner membrane of the rear wall of the left ventricle in the first longitudinal pixel array;
in the M ultrasonic image, obtaining a second longitudinal pixel array of the M ultrasonic image at a time point after a second specific time length after one of Q wave, R wave and S wave in the electrocardio QRS wave is generated, and finding out the maximum value of the distance between the inner membrane of the front wall of the left ventricle and the inner membrane of the rear wall of the left ventricle in the second longitudinal pixel array;
and calculating the cardiac ejection fraction according to the minimum value and the maximum value.
6. The method for obtaining cardiac ejection fraction by multi-dynamic parameter processing according to claim 5, wherein the alignment is performed to the same starting time point, specifically, the method according to any one of claims 1 to 4 is used to synchronously display the collected ultrasonic signals and myoelectric signals on a display device; the display time difference of the ultrasonic signals and the myoelectric signals projected to the display device is equal to the acquisition time difference of the acquired signals.
7. The method of claim 5, wherein the cardiac QRS wave and the M-ultrasonic image are acquired by a device having both functions of acquiring cardiac QRS wave and M-ultrasonic image;
the display device is provided with a continuous time axis and a real-time state axis.
8. The method of claim 5, wherein the first specific duration and the second specific duration are calculated by: analyzing a plurality of M ultrasonic images subjected to binarization processing, marking the time of the minimum value of the interval between the inner membrane of the front wall of the left ventricle and the inner membrane of the rear wall of the left ventricle, and calculating the time difference between the time of the occurrence of one of Q wave, R wave and S wave and the time of the occurrence of the minimum value to obtain a first specific time length;
and calculating the time difference between the time of occurrence of one of the Q wave, the R wave and the S wave and the time of occurrence of the maximum value to obtain a second specific time length.
9. The method of claim 5, wherein after obtaining the minimum and maximum values of the distance between the anterior intima and the posterior intima of the left ventricle, the cardiac ejection fraction is calculated by the following calculation formula EF ═ EDV-ES (100%), where EF is the cardiac ejection fraction, and EDV is the maximum volume of the left ventricle of the heart at the maximum distance between the anterior and posterior intima of the left ventricle; minimum volume of the left ventricle of the heart at minimum distance of the anterior-posterior intima of the left ventricle of the ES heart;
wherein, the maximum volume of the left ventricle of the heart is calculated by the minimum distance between the front wall and the back wall of the left ventricle of the heart; and calculating the maximum volume of the left ventricle of the heart according to the maximum distance between the front wall and the back wall of the inner membrane of the left ventricle of the heart.
10. The method of obtaining cardiac ejection fraction using multi-dynamic parameter processing as claimed in claim 5, wherein the M ultrasound image is formed by: the horizontal pixel rows parallel to the time axis and the vertical pixel rows perpendicular to the time axis.
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