CN114146014A - Compound menthyl nicotinate plant polysaccharide emulsifiable paste and preparation method thereof - Google Patents
Compound menthyl nicotinate plant polysaccharide emulsifiable paste and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a compound menthyl nicotinate plant polysaccharide emulsifiable paste which comprises the following raw materials in percentage by mass: 1.0-1.5% of menthyl nicotinate, 7-10% of lithospermum oil, 0.5-1.5% of pomegranate seed oil, 1.0-1.5% of argan oil, 2-5% of polysaccharide extract, 3-6% of traditional Chinese medicine extract, 11.5-12.5% of auxiliary agent and the balance of deionized water; the preparation method comprises the following steps: (1) weighing the raw materials; (2) preheating and melting menthyl nicotinate, lithospermum oil, pomegranate seed oil, argan oil and an auxiliary agent to obtain an oil phase; (3) adding the polysaccharide extract and the Chinese medicinal material extract into deionized water, and dissolving to obtain a water phase; (4) homogenizing and emulsifying the oil phase and the water phase, cooling to room temperature, standing, and packaging. The cream has the effects of resisting bacteria and inflammation, beautifying skin and resisting wrinkles, relieving pain and itching, and removing warts and scars, and can be widely applied to skin maintenance and treatment.
Description
Technical Field
The invention relates to the technical field of pharmaceutical and cosmetic formulations and preparation, in particular to innovation of a compound menthyl nicotinate plant polysaccharide emulsifiable paste formulation and research of a preparation method thereof.
Background
With the continuous progress of social economy and the abundance of material life, cosmetics called as 'beautiful economy' are expanded from simple quantity to structural optimization, and enjoying healthy and environment-friendly low-carbon life becomes a consensus of more and more consumers in China. Following the trend of environmental protection, natural and green skin care products are pursued in production and use, and environmental protection is a necessary development trend of the skin care product industry.
In recent years, pure natural products and organic products are sought after, which is a development hotspot of the skin care product market in the future and is also a key field for strengthening research and development of various skin care product enterprises. Especially, active products with added active skin microcirculation, natural Chinese herbal medicines and polysaccharide, which have the effects of beautifying and treating and have the similar medicine characteristics, gradually become the mainstream of the cosmetic market in recent years.
Therefore, the problem to be solved by those skilled in the art is how to provide a skin care product with excellent efficacy, practicality and multiple functions.
Disclosure of Invention
In view of the above, the invention aims to provide a compound menthyl nicotinate plant polysaccharide emulsifiable paste and a preparation method thereof, and provide a high-quality skin care product with excellent efficacy, practicability and multiple functions for consumers.
In order to achieve the purpose, the invention adopts the following technical scheme:
the compound menthyl nicotinate plant polysaccharide cream comprises the following raw materials in percentage by mass: 1.0-1.5% of menthyl nicotinate, 7-10% of lithospermum oil, 0.5-1.5% of pomegranate seed oil, 1.0-1.5% of argan oil, 2-5% of polysaccharide extract, 3-6% of traditional Chinese medicine extract, 11.5-12.5% of auxiliary agent and the balance of deionized water.
The application of cosmetology of pharmaceutical cosmetics is one of the Chinese medical external treatment methods. From the viewpoint of modern medicine, the skin-care product improves the microcirculation condition of the skin and enhances the vigorous disease resistance and repair capability of the skin through the transdermal absorption of the active ingredients so as to achieve the aim of delaying the skin aging.
The invention selects menthyl nicotinate as a first component, and takes lithospermum oil, pomegranate seed oil, argan oil, polysaccharide extract, lithospermum, pseudo-ginseng, honeysuckle, Japanese ampelopsis root, densefruit pittany root-bark, Chinese angelica, astragalus and other Chinese herbal medicine extracts as auxiliary components, so that the product has the effects of promoting blood circulation, relieving pain, dispelling wind, removing dampness, inhibiting bacterial growth, resisting inflammation, relieving pain, softening pimples, inhibiting scar hyperplasia, promoting skin blood circulation, increasing skin elasticity and inhibiting melanin generation.
The cream of the invention selects mild oil and auxiliary agent as matrix, so that the product has wider applicability and can be used by all ages, women and children.
In the present invention, menthyl nicotinate is an ester formed by the reaction of menthol and nicotinic acid, and the molecular formulaIs C16H23NO2It can be used as medicine for preventing and treating dermatosis and similar vitamin deficiency, has effects of dilating blood vessel, and treating peripheral nerve spasm and arteriosclerosis, so it has dispersing effect.
The compound menthyl nicotinate plant polysaccharide emulsifiable paste has the excellent performance that menthyl nicotinate is added in the formula, and the menthyl nicotinate is the ester of menthol and nicotinic acid and is a mint derivative.
Menthyl nicotinate is an ester, also a long-lasting, odorless cooling agent, with a slight mint odor that tastes little to no taste, but with a long-lasting, pleasant cooling effect, and is recognized as an excellent cooling agent with no adverse effects such as burning, stinging, and tingling. The menthyl nicotinate is an active ingredient in the compound menthyl nicotinate plant polysaccharide cream, is used for treating cellulites inflammation (a bacterial infection of skin wounds, when the bacterial infection invades the subcutaneous fat layer of the skin, because the arrangement mode of the subcutaneous fat is just like a honeycomb), activates skin microcirculation, and is an esterified substance for local inflammation diminishing and pain relieving.
A person lacking nicotinic acid will have a pellagra (also called pellagra). The menthyl nicotinate is ester, is mild in performance, tasteless and non-irritant, has better skin-friendly performance than nicotinic acid, has double effects of activating skin cells, quickly repairing skin injury, resisting wrinkles and beautifying skin, cooling mint, relieving pain and itching, and avoids the side effects of skin greasiness and discomfort, pore blockage and strong odor of mint and coolness and shortness in use of the niacin cream.
Mint is pungent in flavor and cool in nature. It enters lung and liver meridians. Has effects in dispelling pathogenic wind and heat, refreshing brain, relieving sore throat, promoting eruption, and relieving itching. Can also be used for measles and rubella, unsmooth eruption, skin pruritus and other symptoms; it can be used for external application to contract blood vessels of mucosa, and relieve pain and itching due to sensory nerve paralysis. The cool type product generally adopts mint as a cooling agent. But the volatility and the irritation of the mint are very high, so that the cooling effect is strong and short, and the special mint flavor can cover the due aroma of the paste.
The product has the effects of resisting pellagra, treating skin honeycomb tissue infection and repairing skin tissue injury by the nicotinic acid and also has the functions of promoting eruption and relieving itching by the mint due to the use of the menthyl nicotinate in the product. Also meets the requirement of cool and refreshing fragrance of the product.
Secondly, the oil extract of lithospermum erythrorhizon, namely lithospermum erythrorhizon oil, has the functions of cooling blood, activating blood circulation, detoxifying and promoting eruption in cream, and is used for treating skin diseases such as warm-toxicity macula, extremely toxic deficiency heat, purple black macula and the like of skin; radix Arnebiae has effects of clearing away heat and toxic materials, removing blood stasis, and relieving swelling, and can be used for treating acne.
The pomegranate seed oil has strong capabilities of eliminating free radicals of a human body and delaying senescence. The pomegranate seed oil can be added into cosmetics for whitening skin, removing wrinkle, and delaying aging. The pomegranate seed oil also contains various vitamins, can inhibit the growth of bacteria, and can effectively promote the metabolism of cells.
Argan oil, a substance extracted from argan nuts in argan, has been widely used in recent years, and is called liquid gold because of its excellent efficacy, although it is extracted from nuts and has a remarkable effect in long-term use. The argan nut oil contains a large amount of vitamin E and components such as fatty acid beneficial to skin, so that the argan nut oil can play a role in beautifying and protecting skin after being used on skin, the skin can be very smooth and fine after being used for a long time, toxic substances in pores can be eliminated, the skin is clean and bright, and the argan nut oil can effectively help the skin to play an anti-oxidation role.
Further, the polysaccharide extract is at least one of centella polysaccharide extract, tremella polysaccharide extract, bletilla striata extract, purslane speedwell polysaccharide extract and algal polysaccharide.
The further technical scheme has the beneficial effects that the selected polysaccharide can relieve stimulation, has the characteristics of moisturizing, resisting aging, repairing skin tissues, promoting skin blood circulation and resisting herpes, and is wide in applicability, rapid in itching relieving and high in safety.
Wherein the centella asiatica polysaccharide comprises asiaticoside as main ingredient, and can be used in cosmetics for promoting skin injury healing, and treating dermatosclerosis, ulcer, keloid, acne and fistula. Has certain curative effect on burns, scalds, chemicals, sunburn and the like.
Tremella polysaccharides are the main components of Tremella. The formula of the invention can repair skin, increase surface skin moisture, strengthen self-protection barrier of skin, activate epidermal cells of skin, keep skin tender and moist, repair skin damage caused by ultraviolet irradiation, thereby achieving the effects of eliminating wrinkles and keeping skin young.
The rhizoma bletilla polysaccharide has effects of whitening skin, removing speckle, sterilizing, diminishing inflammation, resisting wrinkle, and resisting aging.
The purslane polysaccharide has the functions of diminishing inflammation, sterilizing and repairing cells, and has certain curative effect on skin diseases such as acne, furuncle, carbuncle, mosquito bite, eczema, erysipelas and the like;
algal polysaccharide is an excellent emollient. The trehalose has good effects of moisturizing, whitening, eliminating acne, repairing body cell injury, and removing scars and spots. It not only can supply moisture, can lock moisture, prevents that moisture from losing. Secondly, the natural seaweed also has the function of controlling oil. The seaweed can increase skin firmness, regulate dry and oily skin, and make it as neutral as possible.
Further, the above Chinese medicinal material extract is at least one of Notoginseng radix extract, flos Lonicerae extract, radix Ampelopsis extract, cortex Dictamni Radicis extract, radix Angelicae sinensis extract and radix astragali extract.
The further beneficial effects of the adoption of the method are that the pseudo-ginseng has the functions of stopping bleeding, dissipating blood stasis, reducing swelling and relieving pain; improving and strengthening coronary microcirculation; anti-inflammatory and anti-fatigue; anti-tumor and analgesic effects; can be used for treating various internal and external hemorrhage, thoracico-abdominal pain, and traumatic injury with swelling and pain.
The Chinese herbal medicines such as honeysuckle, Japanese ampelopsis, cortex dictamni, angelica sinensis, astragalus mongholicus and the like have the effects of beautifying, fading freckles, color spots, scars left by acne and the like, preventing infection of skin bacteria, fungi and the like, preventing folliculitis, dermatitis, eczema and fungal dermatophytosis, resisting oxidation, improving blood microcirculation, delaying senescence, removing wrinkles and the like.
Further, the auxiliary agent is at least one of glyceryl stearate, polyoxyethylene lanolin alcohol ether, spermaceti, acetylated lanolin and auxiliary emulsifier.
The compound menthyl nicotinate plant polysaccharide emulsifiable paste has the functions of skin care and skin care of common emulsions, and is endowed with comprehensive excellent effects:
1. menthyl nicotinate can activate skin microcirculation, and prevent and treat cellulitis inflammation;
2. the tremella polysaccharide is tender and smooth, moistens the skin and eliminates wrinkles;
3. scar removal of centella asiatica polysaccharide promotes wound healing;
4. herba Portulacae polysaccharide has effects of repairing cell injury, resisting bacteria, relieving inflammation, and delaying aging;
5. the algal polysaccharide can eliminate acne, remove scars and spots;
6. the honeysuckle has the functions of maintaining beauty and keeping young, preventing skin bacterial and fungal infection, removing wrinkles and delaying senility;
7. the lithospermum has the effects of clearing away heat and toxic materials, promoting blood circulation, relieving swelling, promoting eruption and removing ecchymoses, and can be used for treating burn, scald, sore and other symptoms;
8. the Chinese herbal medicines such as the ampelopsis japonica, the cortex dictamni, the astragalus and the like have the synergistic effects of clearing heat and removing toxicity, and removing warts and scars.
The innovation points of the invention are as follows: the addition of menthyl nicotinate in the formula; the menthyl nicotinate plant polysaccharide cream is natural and combines usability and functionality by adding the plant polysaccharide cream and the Chinese herbal medicine extract; combining topical skin treatment and maintenance; can achieve the purposes of treating both principal and secondary aspect of disease, treating both internal and external aspects of human body or nourishing the internal and external aspects.
In view of the excellent effects of antisepsis, anti-inflammation, skin beautifying, wrinkle removing, pain easing, itching relieving, wart removing and scar removing of the compound menthyl nicotinate plant polysaccharide cream, the cream can be widely applied to skin maintenance and treatment; the cream is prepared from excellent matrix raw materials, has excellent skin affinity, is soft, tasteless, moist and non-irritant, is suitable for all groups including pregnant women, and can be used in a large area; it can also be used as hemorrhoid ointment for skin mucosa, and is suitable for external application for treating mild gynecological inflammation.
A preparation method of compound menthyl nicotinate plant polysaccharide cream specifically comprises the following steps:
(1) weighing the raw materials according to the mass percentage of the compound menthyl nicotinate plant polysaccharide emulsifiable paste;
(2) adding menthyl nicotinate, lithospermum oil, pomegranate seed oil, argan oil and an auxiliary agent into a preheating tank for preheating, starting stirring until the oil is completely melted when the oil is melted, and obtaining an oil phase;
(3) adding the polysaccharide extract and the Chinese medicinal material extract into deionized water, heating and stirring to dissolve completely to obtain water phase;
(4) pressing the oil phase and the water phase into a homogenizing emulsifier through a pipeline with a filter screen, starting stirring for homogenizing emulsification, then cooling to room temperature, standing and filling to obtain the compound menthyl nicotinate plant polysaccharide cream.
Further, in the step (2), the preheating temperature is 70-80 ℃.
Further, in the step (4), the stirring time is 2 hours; the standing time is 24 h.
In conclusion, compared with the prior art, the compound menthyl nicotinate plant polysaccharide cream has the following beneficial effects:
1. has the effects of resisting bacteria and diminishing inflammation, beautifying skin and resisting wrinkles, relieving pain and itching, and removing warts and scars, and can be widely applied to the maintenance and treatment of skin;
2. the cream is made of excellent substrate raw materials, has excellent skin affinity, is soft, tasteless, moist and non-irritant, is suitable for all groups including pregnant women, and can be used in a large area;
3. can be used as hemorrhoid ointment at skin mucosa, and is also suitable for external application for treating mild gynecological inflammation;
4. it is effective for resisting allergy and is suitable for sensitive skin.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The compound menthyl nicotinate plant polysaccharide cream comprises the following raw materials: 1.0g of menthyl nicotinate, 10g of lithospermum oil extracted from No. 11 white oil, 0.5g of pomegranate seed oil, 1.0g of argan oil, 2.5g of glyceryl stearate, 2g of polyoxyethylene lanonol ether, 5g of spermaceti, 2g of acetylated lanolin, 1.0g of auxiliary emulsifier, 0.5g of centella asiatica polysaccharide extracting solution, 1.0g of tremella polysaccharide extracting solution, 1.0g of bletilla striata extract, 1.0g of purslane polysaccharide extracting solution, 1.5g of algal polysaccharide, 3g of Chinese medicinal material extracts (pseudo-ginseng powder, honeysuckle, Japanese ampelopsis root, densefruit pittany root-bark, angelica and astragalus root) and 67.0g of deionized water;
the preparation method of the compound menthyl nicotinate plant polysaccharide cream specifically comprises the following steps:
(1) weighing the raw materials according to the mass of the compound menthyl nicotinate plant polysaccharide emulsifiable paste;
(2) adding menthyl nicotinate, 11 # white oil extracted arnebia oil, pomegranate seed oil, argan oil, glyceryl stearate, polyoxyethylene lanolin alcohol ether, spermaceti wax, acetylated lanolin and auxiliary emulsifier into a preheating tank, preheating at 75 ℃, starting stirring until the mixture is completely melted when the mixture is melted, and obtaining an oil phase;
(3) adding herba Centellae polysaccharide extractive solution, Tremella polysaccharide extractive solution, rhizoma Bletillae extract, herba Portulacae polysaccharide extractive solution, algal polysaccharide, and Chinese medicinal material extract (Notoginseng radix powder, flos Lonicerae, radix Ampelopsis, cortex Dictamni Radicis, radix Angelicae sinensis and radix astragali) into deionized water, heating and stirring to dissolve completely to obtain water phase;
(4) keeping the temperature of the oil phase and the water phase, pressing the oil phase and the water phase into a homogenizing emulsifier through a pipeline with a filter screen, starting stirring for homogenizing emulsification for 2h, then cooling to room temperature, standing for 24h, and filling to obtain the compound menthyl nicotinate plant polysaccharide emulsifiable paste.
Example 2
The compound menthyl nicotinate plant polysaccharide cream comprises the following raw materials: 1.5g of menthyl nicotinate, 8g of lithospermum oil extracted from No. 11 white oil, 1g of pomegranate seed oil, 1.5g of argan oil, 2.5g of glyceryl stearate, 2g of polyoxyethylene lanonol ether, 4g of spermaceti, 2g of acetylated lanolin, 1.0g of auxiliary emulsifier, 1.0g of centella polysaccharide extract, 2.0g of tremella polysaccharide extract, 1.5g of bletilla striata extract, 1.0g of purslane polysaccharide extract, 2g of algal polysaccharide, 4g of Chinese medicinal material extract (pseudo-ginseng powder, honeysuckle, Japanese ampelopsis root, dittany bark, angelica and astragalus root) and 65.0g of deionized water;
the preparation method of the compound menthyl nicotinate plant polysaccharide cream specifically comprises the following steps:
(1) weighing the raw materials according to the mass of the compound menthyl nicotinate plant polysaccharide emulsifiable paste;
(2) adding menthyl nicotinate, 11 # white oil extracted arnebia oil, pomegranate seed oil, argan oil, glyceryl stearate, polyoxyethylene lanolin alcohol ether, spermaceti wax, acetylated lanolin and auxiliary emulsifier into a preheating tank, preheating at 70 ℃, starting stirring until the mixture is completely melted when the mixture is melted, and obtaining an oil phase;
(3) adding herba Centellae polysaccharide extractive solution, Tremella polysaccharide extractive solution, rhizoma Bletillae extract, herba Portulacae polysaccharide extractive solution, algal polysaccharide, and Chinese medicinal material extract (Notoginseng radix powder, flos Lonicerae, radix Ampelopsis, cortex Dictamni Radicis, radix Angelicae sinensis and radix astragali) into deionized water, heating and stirring to dissolve completely to obtain water phase;
(4) keeping the temperature of the oil phase and the water phase, pressing the oil phase and the water phase into a homogenizing emulsifier through a pipeline with a filter screen, starting stirring for homogenizing emulsification for 2h, then cooling to room temperature, standing for 24h, and filling to obtain the compound menthyl nicotinate plant polysaccharide emulsifiable paste.
Example 3
The compound menthyl nicotinate plant polysaccharide cream comprises the following raw materials: 2.0g of menthyl nicotinate, 7g of lithospermum oil extracted from No. 11 white oil, 1.5g of pomegranate seed oil, 1.5g of argan oil, 2.0g of glyceryl stearate, 3g of polyoxyethylene lanonol ether, 4g of spermaceti, 2g of acetylated lanolin, 1.0g of auxiliary emulsifier (24.0 g of total amount of oil phase components), 1.0g of centella polysaccharide extract, 2.0g of tremella polysaccharide extract, 1.5g of bletilla extract, 1.0g of purslane polysaccharide extract, 2g of algal polysaccharide, 6g of Chinese medicinal material extract (pseudo-ginseng powder, honeysuckle flower, Japanese ampelopsis root, dittany bark, Chinese angelica and astragalus root) and 62.5g of deionized water;
the preparation method of the compound menthyl nicotinate plant polysaccharide cream specifically comprises the following steps:
(1) weighing the raw materials according to the mass of the compound menthyl nicotinate plant polysaccharide emulsifiable paste;
(2) adding menthyl nicotinate, 11 # white oil extracted arnebia oil, pomegranate seed oil, argan oil, glyceryl stearate, polyoxyethylene lanolin alcohol ether, spermaceti wax, acetylated lanolin and auxiliary emulsifier into a preheating tank, preheating at 80 ℃, starting stirring until the mixture is completely melted when the mixture is melted, and obtaining an oil phase;
(3) adding herba Centellae polysaccharide extractive solution, Tremella polysaccharide extractive solution, rhizoma Bletillae extract, herba Portulacae polysaccharide extractive solution, algal polysaccharide, and Chinese medicinal material extract (Notoginseng radix powder, flos Lonicerae, radix Ampelopsis, cortex Dictamni Radicis, radix Angelicae sinensis and radix astragali) into deionized water, heating and stirring to dissolve completely to obtain water phase;
(4) keeping the temperature of the oil phase and the water phase, pressing the oil phase and the water phase into a homogenizing emulsifier through a pipeline with a filter screen, starting stirring for homogenizing emulsification for 2h, then cooling to room temperature, standing for 24h, and filling to obtain the compound menthyl nicotinate plant polysaccharide emulsifiable paste.
Performance testing
1. Index testing
The compound menthyl nicotinate plant polysaccharide cream prepared in the embodiments 1-3 is taken, and the performance detection is carried out according to the QB/T1857-2013 cosmetic cream standard. The results are shown in Table 1.
TABLE 1 EXAMPLES 1-3 Compound Mentholum nicotinate plant polysaccharide cream index test results
As can be seen from Table 1, the compound menthyl nicotinate plant polysaccharide cream in the embodiments 1-3 of the invention is fine and smooth in cream body and easy to spread; herbal cooling aroma; the pale purple color imparted by arnebia oil; the temperature is 40 +/-1/24 h, and no oil-water separation phenomenon exists after the room temperature is recovered; no oil-water separation phenomenon after the room temperature is recovered at minus 10 +/-1/24 h.
The tests show that the product quality and performance of the compound menthyl nicotinate plant polysaccharide emulsifiable paste in the embodiments 1-3 of the invention can reach the standard requirements.
2. Human body test
The compound menthyl nicotinate plant polysaccharide creams prepared in the embodiments 1-3 are respectively taken and used in a mode of being applied to skin or affected parts.
The using method comprises the following steps: a little cream is taken and massaged outward from the center with finger-belly force until it is completely absorbed by the skin.
The results of use: the trial of multiple people in each age period shows that the reaction is good and the excellent effect is achieved.
The tests show that the compound menthyl nicotinate polysaccharide cream is prepared by using menthyl nicotinate as a main material and using pomegranate seed oil, polysaccharide, lithospermum and other Chinese herbal medicine extracting solutions as auxiliary materials, relates to two aspects of medicine compatibility and paste matrix formula in the theory of medicine, and belongs to two different technical fields. The compound menthyl nicotinate plant polysaccharide cream successfully plays a unique role in nourishing skin, promoting skin blood circulation, preventing skin aging, externally treating internal diseases and preventing and treating external diseases for consumers. The successful development of the method can create good economic and social benefits for enterprises while bringing good news to people.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (8)
1. The compound menthyl nicotinate plant polysaccharide cream is characterized by comprising the following raw materials in percentage by mass: 1.0-1.5% of menthyl nicotinate, 7-10% of lithospermum oil, 0.5-1.5% of pomegranate seed oil, 1.0-1.5% of argan oil, 2-5% of polysaccharide extract, 3-6% of traditional Chinese medicine extract, 11.5-12.5% of auxiliary agent and the balance of deionized water.
2. The compound menthyl nicotinate plant polysaccharide cream as claimed in claim 1, wherein the polysaccharide extract is at least one of centella asiatica polysaccharide extract, tremella polysaccharide extract, bletilla striata extract, purslane polysaccharide extract and algal polysaccharide.
3. The compound menthyl nicotinate plant polysaccharide cream as claimed in claim 1, wherein the Chinese herbal medicine extract is at least one of pseudo-ginseng extract, honeysuckle extract, ampelopsis japonica extract, cortex dictamni extract, angelica sinensis extract and astragalus membranaceus extract.
4. The compound menthyl nicotinate plant polysaccharide cream as claimed in claim 1, wherein the adjuvant is at least one of glyceryl stearate, polyoxyethylene lanolin alcohol ether, spermaceti wax, acetylated lanolin and auxiliary emulsifier.
5. The preparation method of the compound menthyl nicotinate plant polysaccharide cream is characterized by comprising the following steps:
(1) weighing the raw materials according to the mass percentage of the compound menthyl nicotinate plant polysaccharide cream of any one of claims 1 to 4;
(2) adding menthyl nicotinate, lithospermum oil, pomegranate seed oil, argan oil and an auxiliary agent into a preheating tank for preheating, starting stirring until the oil is completely melted when the oil is melted, and obtaining an oil phase;
(3) adding the polysaccharide extract and the Chinese medicinal material extract into deionized water, heating and stirring to dissolve completely to obtain water phase;
(4) pressing the oil phase and the water phase into a homogenizing emulsifier through a pipeline with a filter screen, starting stirring for homogenizing emulsification, then cooling to room temperature, standing and filling to obtain the compound menthyl nicotinate plant polysaccharide cream.
6. The preparation method of the compound menthyl nicotinate plant polysaccharide cream as claimed in claim 5, characterized in that in the step (2), the preheating temperature is 70-80 ℃.
7. The preparation method of the compound menthyl nicotinate plant polysaccharide cream as claimed in claim 5, characterized in that in the step (4), the stirring time is 2 h.
8. The preparation method of the compound menthyl nicotinate plant polysaccharide cream as claimed in claim 5, characterized in that in the step (4), the standing time is 24 h.
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| CN115227588A (en) * | 2022-08-05 | 2022-10-25 | 温州医科大学慈溪生物医药研究院 | Cream for preventing skin dark spots |
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| CN115227588A (en) * | 2022-08-05 | 2022-10-25 | 温州医科大学慈溪生物医药研究院 | Cream for preventing skin dark spots |
| CN115227588B (en) * | 2022-08-05 | 2023-10-31 | 温州医科大学慈溪生物医药研究院 | Cream for protecting skin from dark spots |
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