CN114018907A - Detection device of integrated detection test paper and use method thereof - Google Patents
Detection device of integrated detection test paper and use method thereof Download PDFInfo
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- CN114018907A CN114018907A CN202111292703.2A CN202111292703A CN114018907A CN 114018907 A CN114018907 A CN 114018907A CN 202111292703 A CN202111292703 A CN 202111292703A CN 114018907 A CN114018907 A CN 114018907A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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Abstract
The utility model provides a detection apparatus for test paper integrates, which comprises an outer shell, the displacement regulator, the shower head, the cavity, the shell is the cylinder type, the cavity is used for holding the shower head, the displacement regulator, discoid test paper integrates, wherein, the displacement regulator includes the rack, the gear, the knob, the tooth axle, the pivot, the draw-in groove, the pivot sets up in the center of cavity, rack and gear set up respectively in the shell wall, tooth axle one end connection gear, tooth axle other end connection pivot, the shower head passes through bayonet socket and draw-in groove connection, when implementing the operation, the shower head revolutes the rotatory operation of axle, make sample or reagent spray discoid test paper's reagent piece that integrates, accomplish discoid test paper's detection that integrates.
Description
Technical Field
The invention relates to a medical detection technology, in particular to a detection method, a detection device and a detection system of integrated detection test paper.
Background
The test paper detection is a common medical detection technology, wherein hundreds of small-size reagent blocks are integrated on one test paper strip by an integrated detection test paper, and hundreds of indexes can be detected by using a small amount of samples once.
Conventional methods for detecting a test strip, such as dipping the test strip into a specimen, dropping the specimen onto a test strip with a dropper, or coating the specimen onto the test strip, are not suitable for integrated test strips. The reasons include: (1) the reagent blocks of the integrated test paper are unevenly soaked, part of the reagent blocks are excessively soaked to cause interference among the reagent blocks and sample waste, and part of the reagent blocks are insufficiently soaked or omitted to cause inaccurate results or missed test; (2) the size of the integrated detection test paper reagent block is small, and if part of the reagent block is in a color reaction process and a reagent needs to be added, the precise operation and implementation difficulty is high; (3) when the color reaction of the integrated test paper reagent block has special requirements on temperature and humidity, the temperature and humidity can not be adjusted; (4) in the detection process, the biological pollution caused by aerosol cannot be controlled.
In view of this, we design a transparent closed detection device for the detection of integrated test paper, preset the operation procedure, the operation under the visual magnifier, will detect sample or reagent with the reagent piece that the droplet mode subregion sprayed integrated test paper, realize accurate infiltration and integrate each reagent piece of test paper, simultaneously, not extravagant sample and reagent, the temperature of configuration, humidity control assembly provide the temperature and humidity environment that adapt to, and then reach and simplify the operation degree of difficulty, control aerosol pollution, accurate detection and practice thrift sample and reagent effect.
Disclosure of Invention
The invention aims to provide a detection method, a device and a system of integrated detection test paper, which are characterized in that according to a preset program, a magnifying glass is operated under the visual effect, a detection sample or a reagent is sprayed to reagent blocks of the integrated detection test paper in a micro-droplet mode in a partition mode, the sample and the reagent are not wasted while each reagent block of the integrated detection test paper is accurately infiltrated, and the effects of simplifying operation difficulty, accurately detecting and saving the sample and the reagent are further achieved.
The invention adopts the following technical scheme.
The invention provides a detection method of integrated detection test paper, which comprises the following steps.
(1) The method comprises the steps of collecting and preprocessing a specimen to obtain a detection sample, wherein the detection sample is in a liquid state, and the amount of the detection sample is not less than the minimum infiltration amount of the integrated detection test paper and not more than the maximum infiltration amount of the integrated detection test paper.
(2) The method comprises the steps of spraying a sample, transferring the detection sample to an injector, connecting the injector with a spraying and coloring reaction device, placing the integrated detection test paper into the spraying and coloring reaction device, pushing the injector according to a set spraying program in times, enabling the detection sample in the injector to form sample micro-droplets through a spray header, infiltrating part of reagent blocks of the integrated detection test paper by the sample micro-droplets, moving the spray header, pushing the injector again, infiltrating other reagent blocks of the integrated detection test paper by the sample micro-droplets until the sample micro-droplets infiltrate all the reagent blocks of the integrated detection test paper.
(3) The color reaction provides proper conditions of color reaction for a spraying and color reaction device, including temperature and humidity, and promotes the integrated test paper reagent block to generate substrate color reaction or mark color reaction, wherein in the color reaction process, a reagent adding procedure is the same as the step of spraying the sample.
(4) And (3) identification and interpretation, namely putting the integrated test paper with the color reaction into an identification and interpretation device, identifying and collecting the color reaction data of the dot matrix sites of the reagent blocks and the identification codes of the reagent blocks on the integrated test paper by a vision sensor of a display microcomputer of the identification and interpretation device, referring to the color reaction data of the reagent blocks, the negative contrast, the standard contrast and the sample pretreatment dilution ratio of the color reaction data of the reagent blocks, and obtaining the analysis result of the detected sample by using a specific algorithm.
Preferably, the spraying procedure includes a spraying dosage for pushing the injector each time, an interval for each displacement of the spraying device, and a total spraying dosage, for example, the length of the integrated test paper detection area is 50 mm, the width of the integrated test paper detection area is 8 mm, the integrated test paper detection area includes 100 reagent blocks in total of 4 rows and 25 columns, the spraying range of the spraying head of the spraying device is 10 mm by 8 mm each time, the total spraying dosage is 500 microliters of the test sample, and then the spraying procedure is as follows: the spraying dosage of each time of pushing the injector is 100 microlitres, the interval of each time of displacement of the spraying device is 10 millimeters, and 5 spraying operations are needed.
The invention provides a detection device of integrated detection test paper, which comprises a sample collection device, a sample pretreatment device, a spraying and color generation reaction device and an identification and interpretation device, wherein the spraying and color generation reaction device comprises a shell, a displacement regulator and a spray header, the shell comprises a cover, a cavity and an opening, the cover comprises a main body, a lens structure, a top groove and a side groove, the top groove is used for a connector to move along a long shaft, the side groove is used for a gear shaft to move along the long shaft, the cavity is used for accommodating the spray header, the displacement regulator and the integrated detection test paper, the opening is arranged at the bottom of the cavity and is used for placing the integrated detection test paper, the displacement regulator comprises a rack, a gear, a knob, a gear shaft and a clamping groove, the rack and the gear are respectively arranged in pairs on the shell wall, the gears are connected by the gear shaft, the middle section of the gear shaft is provided with the clamping groove, the tail end of the gear shaft on one side is provided with the knob, the knob sets up the scale, rotates scale of knob, drives the gear and removes along the rack, and the shower head that promotes the draw-in groove connection takes place a displacement unit, the shower head includes interface, surge chamber, micropore, bayonet socket, the syringe is connected to interface one end, and the surge chamber is connected to the other end, surge chamber side and bottom surface set up a plurality of micropores, and sample or reagent get into the surge chamber through the interface in the syringe, through the micropore blowout, discernment interpretation device includes lighting components, cartesian robot, end effector, lighting components includes visible light, infrared light, laser, ultraviolet ray, end effector is including showing microcomputer vision sensor, it gathers reagent piece dot matrix site reverberation or excitation light data and reagent piece data on the detection test paper to show microcomputer vision sensor discernment.
Preferably, the housing can be designed into a disc shape, a rotating shaft is arranged in the center of the chamber, the number of the rack and the gear of the displacement regulator is one, the rack and the gear are arranged on the periphery of the housing, one end of the rack is connected with the gear, the other end of the rack is connected with the rotating shaft, and during operation, the spray head rotates around the rotating shaft to spray a sample or a reagent.
Preferably, the chamber comprises a constant temperature component and a constant humidity component, and the constant temperature component and the constant humidity component are respectively used for adjusting the local temperature and humidity of the chamber according to the color reaction requirement.
Preferably, the spray header is divided into a plurality of specification types according to the length, the width and the pore diameter of the micropores, and the detection requirements of the integrated detection test paper are met.
Preferably, the specification and the size of the shell are customized according to the specification and the size of the integrated test paper.
Preferably, the displacement adjuster is dimensioned to be in accordance with the dimensions of the housing.
Preferably, the cover is made of transparent material, and the inner structure of the chamber can be seen through the cover.
Preferably, the lens structure is for covering the main part transparent material local thickening forms the subassembly that has the magnifying lens function for observe the reagent piece dot matrix that integrates the test paper.
The invention provides a detection system of integrated detection test paper, which comprises the integrated detection test paper, a detection device of the integrated detection test paper, an identification interpretation algorithm, software and a cloud server.
Compared with the prior art, the invention has the beneficial effects.
(1) Spraying and be transparent enclosed construction with look reaction unit, see through the lid that has the magnifying lens function, can observe the integrated test paper reagent piece dot matrix of putting into, simultaneously, avoid the biological pollution that aerosol scatters and lead to in the testing process.
(2) Spray with be small and exquisite with the spray head structure of reaction unit that appears, reduce the sample loss that is infected with and leads to, the operation under the magnifying glass is visual, drenches the shower nozzle along with displacement regulator's propulsion, and sample subregion drips and drenches infiltration test paper, avoids test paper reagent piece to soak excessively, not enough or omit, improves sample utilization and detection accuracy nature.
(3) Before detection, the clinical specimen quantity required to be obtained can be accurately estimated according to the minimum infiltration quantity of the integrated detection test paper, so that the problems that the sample quantity is insufficient, secondary collection is required, or the obtained clinical specimen quantity is too much, and the waste of medical resources is caused are avoided.
(4) The spraying and coloring reaction device has the advantages of simple structure, cheap materials, easy customization and repeated use, and is beneficial to reducing the medical detection cost.
Drawings
In order to more clearly illustrate the embodiments or technical solutions in the prior art of the present invention, the drawings used in the description of the embodiments or prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained based on these drawings without inventive labor. Furthermore, these descriptions should not be construed as limiting the embodiments.
FIG. 1 is a flow chart of the integrated test strip.
FIG. 2 is a schematic view of the structure of the housing of the integrated test strip tester.
FIG. 3 is a schematic diagram of a displacement regulator of the integrated test strip tester.
FIG. 4 is a schematic view of a spray head structure of the integrated test strip detection device.
FIG. 5 is a schematic diagram of a disc-shaped housing of the integrated test strip tester.
FIG. 6 is a schematic diagram of a disc-shaped displacement adjuster of the integrated test strip tester.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present invention is further illustrated below with reference to specific examples. It is to be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention, which is to be given the full breadth of the appended claims and any and all equivalent modifications thereof which may occur to those skilled in the art upon reading the present specification.
It should be noted that the terms of directions such as up, down, left, right, front, back, side, far, near, and end of the present embodiment are only relative concepts or reference to the normal use status of the product, and should not be considered as limiting.
As shown in fig. 1-6, the embodiment of the invention discloses a detection method, a detection device and a detection system for an integrated test strip.
Referring to fig. 1, a flow 100 of an integrated test strip according to an embodiment of the present invention includes the following steps.
And 110, collecting a sample, wherein the sample collection amount is not less than the minimum amount required by the integrated test paper, the sample comprises a clinical sample and an environmental sample, the clinical sample comprises but is not limited to blood, urine, excrement, hydrothorax and ascites, cerebrospinal fluid, prostatic fluid, semen, leucorrhea, saliva, vomit, wound or body surface eluent, and the environmental sample comprises but is not limited to soil, water, animal tissue and plant tissue.
And 120, pretreating the sample, namely pretreating the sample collected in the step 110 to obtain a detection sample, wherein the detection sample is in a liquid state, and the amount of the detection sample is not less than the minimum infiltration amount of the integrated detection test paper, wherein blood is drawn from a vein or punctured from a tip to prepare blood plasma or blood plasma diluent, feces is prepared to prepare feces filtrate, and plant tissues and animal tissues are prepared to prepare eluent or tissue homogenate.
130, put into and integrate the test paper, will select integrate the test paper and put into the spraying and the reaction unit that appears that the specification matches, it is ascending to integrate the test paper detection zone, integrates that the blank part of test paper exposes outside spraying and the reaction unit that appears, conveniently puts into and takes out and integrates the test paper.
140, spraying a sample, transferring the detection sample prepared in the step 120 to an injector, connecting the injector with the spraying and color-generating reaction device in the step 130, pushing the injector in times according to a preset spraying program, operating under the visual effect of a magnifier, forming sample micro-droplets by the detection sample in the injector through a spray header, infiltrating part of reagent blocks of the integrated detection test paper with the sample micro-droplets, moving the spray header, pushing the injector again, and infiltrating other reagent blocks of the integrated detection test paper with the sample micro-droplets; the spraying program calculates the spraying times through the size of the spray header, the spraying dosage each time, the displacement distance of the spray header each time and the total spraying dosage, allows a few reagent blocks to be sprayed in an overlapping mode, and avoids omission of the reagent blocks.
150, color reaction, spraying the test sample by the integrated test paper reagent block in the step 140, fully soaking, and then generating the color reaction, wherein the spraying and color reaction device in the step 130 provides proper conditions for the color reaction, and the method also comprises the following steps.
And 152, controlling the temperature, monitoring the internal temperature of the spraying and color-generating reaction device in real time, starting a temperature control component when necessary, keeping the optimal color-generating reaction temperature at 42 ℃, or adjusting the temperature to a specific appropriate temperature required by specific integrated test paper.
And 154, controlling the humidity, monitoring the humidity inside the spraying and color reaction device in real time, and starting a humidity control assembly when necessary to keep the optimal color reaction humidity.
156, adding reagent, and in the process of the substrate color reaction or the mark color reaction of the integrated test paper reagent block, adding the reagent, wherein the reagent adding procedure is the same as the spraying operation in the step 140.
And 160, identification and interpretation, namely taking the integrated test paper subjected to the color reaction in the step 150 out of the spraying and color reaction device, then putting the integrated test paper into an identification and interpretation device, and identifying and collecting the color reaction data of the dot matrix sites of the reagent blocks and the identification codes of the reagent blocks on the integrated test paper by a vision sensor of a display microcomputer of the identification and interpretation device.
170, analyzing the result, the data processor receives the data collected by the microcomputer vision sensor in the step 160, and the detection result of the sample is obtained by the specific algorithm according to the color reaction data of the reference reagent block, the negative control, the standard control and the sample pretreatment dilution ratio.
An embodiment of the present invention provides a device 200 for detecting an integrated test strip, which includes a sample collecting device, a sample preprocessing device, a spraying and coloring reaction device 210, and an identification and interpretation device, and referring to fig. 2, fig. 3, and fig. 4, it discloses a spraying and coloring reaction device 210 suitable for a strip-shaped integrated test strip 300.
The spraying and color reaction device 210 comprises a shell 211, a displacement regulator 212, a spraying head 213 and a chamber 214, wherein the shell 211 comprises a cover 211-1, a shell 211-2 and an opening 211-3, the cover 211-1 comprises a main body 211-1-1, a lens structure 211-1-2, a top groove 211-1-3 and a side groove 211-1-4, the top groove 211-1-3 is used for the interface 213-1 to move along a long axis, the side groove 211-1-4 is used for the gear shaft 212-4 to move along the long axis, the chamber 214 is used for accommodating the spraying head 213, the displacement regulator 212 and the integrated detection test paper 300, and the opening 211-3 is arranged on the right side of the bottom of the chamber 214 and is used for accommodating the long strip integrated detection test paper 300.
The displacement adjuster 212 comprises a rack 212-1, a gear 212-2, a knob 212-3, a gear shaft 212-4 and a clamping groove 212-5, wherein the rack 212-1 comprises a proximal rack 212-1A and a distal rack 212-1B, respectively, the gear 212-2 comprises a proximal gear 212-2A and a distal gear 212-2B, respectively, the proximal rack 212-1A and the proximal gear 212-2A are disposed in the chamber 214 and fixed on the proximal wall of the housing 211, the distal rack 212-1A and the distal gear 212-2A are disposed in the chamber 214 and fixed on the distal wall of the housing 211, the proximal gear 212-2A and the distal gear 212-2B are connected by the gear shaft 212-4, the clamping groove 212-5 is disposed in the middle section of the gear shaft 212-4, the clamping groove 212-5 is connected with the spray header 213 through a clamping opening 213-4, the clamping groove 212-5 can change positions on the gear shaft 212-4 according to requirements, wherein the tail end of the gear shaft 212-4 near the side extends out of the outer shell 211, the knob 212-3 is installed at the end of the gear shaft 212-4 extending out of the outer shell 211, scales are arranged on the knob 212-3, the knob 212-3 is rotated for one scale, the gear 212-2 is driven to move along the rack 212-1, and the spray header 213 connected with the clamping groove 212-5 is pushed to generate one displacement unit.
The spray head 213 comprises an interface 213-1, a buffer chamber 213-2, micropores 213-3 and a bayonet 213-4, the upper end of the interface 213-1 is connected with a syringe, the lower end of the interface 213-1 is communicated with the buffer chamber 213-2, the side surface and the bottom surface of the buffer chamber 213-2 are provided with a plurality of micropores 213-3, and a sample or a reagent in the syringe enters the buffer chamber 213-2 through the interface 213-1 and is sprayed out through the micropores 213-3.
When in use, the length and the width of the detection area of the integrated test paper 300 are determined by referring to the technical standard of the integrated test paper 300, preparing a sample amount between the minimum sample amount and the maximum sample amount of the completely-soaked reagent blocks, selecting a matched spraying and color-generating reaction device 210 and a spraying head 213, opening a cover 211-1, installing the spraying head 213, closing the cover 211-1, placing a strip-shaped integrated test paper 300 from an opening 211-3, enabling a detection area of the integrated test paper 300 to face upwards, exposing a blank area of a part of the integrated test paper 300 outside the opening 211-3, rotating a knob 212-3, moving the spraying head 213 to the leftmost side, and adjusting the spraying head 213 to face the left part of the detection area of the integrated test paper 300 through a lens structure 211-1-2 of the cover 211-1 by rotating the knob 212-3; calculating the times of pushing the injection, the dosage of each injection and the moving distance of the spray header 213 each time; the injector pumps in a sample, injects a certain amount of sample, rotates the knob 212-3, the spray header 213 moves a certain distance, injects a certain amount of sample again until the injection of the sample is completed, and observes that all reagent blocks of the integrated test paper 300 are fully soaked through the lens structure 211-1-2 of the cover 211-1; referring to the technical standard of the integrated test paper 300, the suitable environmental temperature and humidity of the integrated test paper 300 are determined, and the temperature and humidity control assembly is started to adjust according to the real-time monitored environmental temperature and humidity in the cavity 214; referring to the technical operation flow of the integrated test strip 300, a reagent to be added is loaded into an injector and coupled to the shower head 213 to add the reagent, if necessary.
Referring to fig. 5 and 6, a spraying and color reaction device 210 suitable for a disc-shaped integrated test strip 300 is disclosed.
The spraying and color-generating reaction device 210 comprises a shell 211, a displacement regulator 212, a spray header 213 and a chamber 214, wherein the shell 211 is cylindrical and comprises a cover 211-1 and a shell 211-2, the cover 211-1 comprises a main body 211-1-1, a lens structure 211-1-2, a top groove 211-1-3 and a side groove 211-1-4, the top groove 211-1-3 is used for the interface 213-1 to move along a long axis, the side groove 211-1-4 is used for the gear shaft 212-4 to move along the long axis, and the chamber 214 is used for accommodating the spray header 213, the displacement regulator 212, a rotating shaft 212-6 and the disc-shaped integrated test paper 300.
The displacement adjuster 212 comprises a rack 212-1, a gear 212-2, a knob 212-3, a gear shaft 212-4, a rotating shaft 212-6 and a clamping groove 212-5, wherein the rack 212-1 and the gear 212-2 surround and are fixed on the wall of the cover 211-1, the gear 212-2 and the rotating shaft 212-6 are connected by the gear shaft 212-4, the clamping groove 212-5 is arranged at the middle section of the gear shaft 212-4, the clamping groove 212-5 is connected with the shower head 213 through the clamping groove 213-4, wherein the tail end of the gear shaft 212-4 extends out of the main body 211-1-1 and is provided with the knob 212-3, the knob 212-3 is provided with scales, and the gear 212-2 is driven to move along the rack 212-1 by rotating the knob 212-3 by one scale, the spray header 213 coupled to the card slot 212-5 is pushed to generate a displacement unit, and when the operation is performed, the spray header 213 rotates around the rotating shaft 212-6 to spray a sample or a reagent to the disk-shaped integrated test paper 300 reagent block.
During the use, refer to the technical standard of integrating test paper 300, confirm the detection zone length and the width of integrating test paper 300, the minimum sample size and the maximum sample size that the reagent piece was totally soaked, the preparation sample size is between the minimum sample size and the maximum sample size that the reagent piece was totally soaked, select the matching spray and look reaction unit 210 and shower head 213, open cover 211-1, put into integrating discoid test paper 300, install shower head 213, close cover 211-1, other operations integrate test paper 300 with rectangular form.
The embodiment of the invention provides a detection system of integrated test paper, which comprises integrated test paper 300, a detection device 200 of the integrated test paper, an identification and interpretation algorithm, software and a server, wherein the identification and interpretation algorithm obtains detection results of hundreds of reagent blocks of the integrated test paper 300 according to the technical standard of the integrated test paper 300, the graphic code of the integrated test paper 300, the chromogenic reaction data of the reagent blocks, blank contrast, negative contrast, positive standard contrast and the dose-effect relationship of chromogenic reaction, the software comprises a rectangular coordinate robot operation code, a microcomputer vision sensor operation code, an identification and interpretation algorithm code and a data safety code, and the server comprises a cloud server.
This application is intended to cover any variations, uses, or adaptations of the invention following, in general, the principles of the invention and including such departures from the present disclosure as come within known or customary practice within the art to which the invention pertains. It is intended that the specification and examples be considered as exemplary only, with a scope of the invention being limited only by the following claims.
Claims (10)
1. A detection device of integrated test paper is used for detecting the disc-shaped integrated test paper, the detection device comprises a sample collection device, a sample pretreatment device, a spraying and coloring reaction device and an identification and interpretation device, the spraying and coloring reaction device comprises a shell, a displacement regulator, a spraying head and a cavity, and is characterized in that,
the shell is cylindrical and comprises a cover and a shell;
the chamber is used for accommodating the spray header, the displacement regulator and the disc-shaped integrated test paper, the displacement regulator comprises a rack, a gear, a knob, a gear shaft, a rotating shaft and a clamping groove, the rotating shaft is arranged at the center of the chamber, the rack and the gear are respectively arranged on the wall of the shell, one end of the gear shaft is connected with the gear, the other end of the gear shaft is connected with the rotating shaft, the spray header is connected with the clamping groove through the bayonet, and during operation, the spray header rotates around the rotating shaft to operate, so that a sample or a reagent is sprayed to a reagent block of the disc-shaped integrated test paper.
2. The device for detecting an integrated test strip according to claim 1,
the cover comprises a main body, a lens structure, a top groove and a side groove, wherein the top groove is used for enabling an interface of the spray head to move circumferentially, and the side groove is used for enabling the displacement regulator to move circumferentially along the shell.
3. The device for detecting an integrated test strip according to claim 1,
the tail end of the gear shaft extends out of the shell, and the knob is installed.
4. The device for detecting an integrated test strip according to claims 1 and 3,
the knob is used for controlling the moving direction and speed of the spray header, scales are arranged on the knob, and the knob is rotated by one scale to drive the gear to move circumferentially along the rack and push the spray header connected with the clamping groove to generate a displacement unit.
5. The device for detecting an integrated test strip according to claim 1,
the bottom of cavity sets up the opening, the opening is used for putting into discoid test paper that integrates.
6. The device for detecting an integrated test strip according to claim 1,
the detection device comprises the spraying and color generation reaction devices with different specifications and is used for matching the disc-shaped integrated detection test paper with different technical standards.
7. The use method of the detection device of the integrated detection test paper is characterized by comprising the following steps,
step 1, collecting a specimen;
step 2, pretreating the sample, namely pretreating the sample collected in the step 1 to obtain a detection sample;
3, placing disc-shaped integrated test paper in the detection device, selecting a spraying and color generation reaction device matched with the disc-shaped integrated test paper, and connecting the spraying and color generation reaction device to the detection device;
step 4, spraying a sample, transferring the detection sample prepared in the step 2 to an injector, connecting the injector with the spraying and color-generating reaction device in the step 3, pushing the injector according to a preset spraying program, operating under the visual effect of a magnifier, forming sample droplets by the detection sample in the injector through a spray header, infiltrating the sample droplets into reagent blocks of the disc-shaped integrated detection test paper, adjusting a knob, moving the spray header, and pushing the injector again until the sample droplets infiltrate all the reagent blocks of the integrated detection test paper;
step 5, color reaction is carried out, and the color reaction is carried out after the reagent blocks of the disc-shaped integrated test paper are sprayed with the test sample and fully soaked in the step 4;
and 6, identifying and interpreting, namely taking the disc-shaped integrated test paper subjected to the color reaction in the step 5 out of the spraying and color reaction device, putting the disc-shaped integrated test paper into an identifying and interpreting device, and identifying and acquiring the color reaction data of the dot matrix sites of the reagent blocks and the identification codes of the reagent blocks of the disc-shaped integrated test paper by a visual sensor of a display microcomputer of the identifying and interpreting device to obtain the detection result of the sample.
8. The use of the test device with integrated test strip of claim 7, wherein in step 5, the method further comprises spraying and providing the color reaction conditions with the color reaction device, wherein the conditions comprise proper temperature, proper humidity and reagent addition.
9. The use of the test device with integrated test strip of claim 7, further comprising a data processor for receiving data collected by the microcomputer vision sensor in step 6, and obtaining the test result of the sample by using a specific algorithm in combination with the data of color reaction of the reagent block of the disk-shaped integrated test strip.
10. The method of using the apparatus for detecting integrated test strips according to claim 9, further comprising, in step 6, cartesian robot operation, microcomputer vision sensor operation, and identification and interpretation operation for obtaining the detection results of hundreds of reagent blocks of the disk-shaped integrated test strip according to the quantitative and effective relationship among the disk-shaped integrated test strip technical standard, the integrated test strip graphic code, the reagent block coloration reaction data, the blank control, the negative control, the positive standard control, and the coloration reaction.
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| CN202111292703.2A CN114018907A (en) | 2020-11-15 | 2020-11-15 | Detection device of integrated detection test paper and use method thereof |
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| CN202111292703.2A CN114018907A (en) | 2020-11-15 | 2020-11-15 | Detection device of integrated detection test paper and use method thereof |
| CN202011324527.1A CN112505027B (en) | 2020-11-15 | 2020-11-15 | Detection method, device and system of integrated detection test paper |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPS59779B2 (en) * | 1977-01-20 | 1984-01-09 | 株式会社京都第一科学 | Analysis method for urine etc. |
| JPH0534291A (en) * | 1991-07-29 | 1993-02-09 | Nippon Steel Corp | Method and apparatus for analyzing minute amount of sulfur and phosphorus in metallic sample |
| CN2745070Y (en) * | 2004-11-24 | 2005-12-07 | 滕浩然 | Automatic urine analyzer |
| CN102455281B (en) * | 2011-03-23 | 2013-03-13 | 杨晓波 | High flux multipurpose liquid sample rapid photoelectric analyzer |
| CN204142700U (en) * | 2014-09-12 | 2015-02-04 | 龙国亮 | A kind of multi-joint drugs intelligent detecting instrument |
| CN104714035B (en) * | 2015-03-12 | 2017-03-15 | 罗阳 | A kind of high flux blood group system detection means and method |
| DE112015006935B4 (en) * | 2015-09-24 | 2020-12-10 | Xiamen Brana Design Co., Ltd. | Smart toilet for examining excrement |
| CN107199061B (en) * | 2017-05-28 | 2021-07-27 | 合肥赫博医疗器械有限责任公司 | Application method of multi-task full-automatic biochemical detection chip |
| CN108008139A (en) * | 2017-10-26 | 2018-05-08 | 厦门波耐模型设计有限责任公司 | A kind of intelligent automatic detection scheme of excreta and its implementation |
| CN107942044B (en) * | 2017-10-26 | 2020-04-14 | 厦门波耐模型设计有限责任公司 | Excrement detection test disc and manufacturing method thereof |
| CN210665508U (en) * | 2019-05-22 | 2020-06-02 | 济南百博生物技术股份有限公司 | Vaginal secretion detector |
-
2020
- 2020-11-15 CN CN202111292703.2A patent/CN114018907A/en not_active Withdrawn
- 2020-11-15 CN CN202011324527.1A patent/CN112505027B/en active Active
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| Publication number | Publication date |
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| CN112505027A (en) | 2021-03-16 |
| CN112505027B (en) | 2021-11-26 |
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