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CN103830591A - Traditional Chinese medicine formula for treating stroke and post-traumatic brain syndrome and preparation method of traditional Chinese medicine - Google Patents

Traditional Chinese medicine formula for treating stroke and post-traumatic brain syndrome and preparation method of traditional Chinese medicine Download PDF

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Publication number
CN103830591A
CN103830591A CN201410101309.XA CN201410101309A CN103830591A CN 103830591 A CN103830591 A CN 103830591A CN 201410101309 A CN201410101309 A CN 201410101309A CN 103830591 A CN103830591 A CN 103830591A
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weight portions
parts
chinese medicine
radix
traditional chinese
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徐增良
张秀苇
张建美
杨青
张立志
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JIAOZHOU PEOPLE'S TRADITIONAL CHINESE MEDICINE HOSPITAL
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JIAOZHOU PEOPLE'S TRADITIONAL CHINESE MEDICINE HOSPITAL
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Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine formula for treating stroke and post-traumatic brain syndrome and a preparation method of the traditional Chinese medicine. According to formula, the traditional Chinese medicine comprises the following components in parts by weight: 195 parts of astragalus, 97.5 parts of red peony root, 97.5 parts of angelica sinensis, 97.5 parts of fried peach seed, 97.5 parts of earthworm, 39 parts of safflower, 65 parts of rhizoma chuanxiong, 195 parts of red sage root, 130 parts of suberect spatholobus stem, 78 parts of medicinal cyathula root and 78 parts of gastrodia tuber. The formula is capable of treating both symptoms and root causes and realizing one-time mass production and is good in symptomatic treatment effect and simple in manufacturing; patent medicine preparations are convenient to carry and take.

Description

A kind of Chinese medicine formula and preparation method for the treatment of apoplexy and cerebral trauma sequela
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine formula and preparation method for the treatment of apoplexy and cerebral trauma sequela.
Background technology
Apoplexy sequela and cerebral trauma sequela many because of after Acute Stroke or cerebral trauma cause disorder of QI and blood, the obstructed hemiplegia causing of blood stasis due to qi deficiency venation, headache, aphasia, facial hemiparalysis or lower limb fistula are useless etc.
Particularly post-traumatic syndrome of traumatic sequela, patient's symptom is varied, main have headache, dizzy, insomnia, dreaminess, attention can not concentrate, forgetful, can not tolerate noise, tinnitus, dim eyesight, paces shakiness, tired, unable, inappetence, personality changes, remain passive and pessimistic, depressed joyless, neck is ached etc., therefore can infer that the organic disease of it and brain may have nothing to do.Pathogenesis for this disease it be unclear that, and most scholars think the result of cerebral vessels dyskinesia.This disease still lacks specific short.
And the existing treatment by Chinese herbs method unsatisfactory curative effect of apoplexy sequela, and the fried time is longer, and bothersome effort, carries inconvenience, can not disposablely produce in enormous quantities.Traumatic sequela is at present without special therapeutic method, and the western medicine time is long, somewhat expensive, and also long-time application can cause the important organ infringements such as Drug Liver and kidney.We think to 200 routine postcerebrotraumatic syndrome patient dialectical Analyses: though primary disease cause because of wound, real be seven emotions in terror due to.In addition, in the time of injury of head, ailment said due to cold or exposure is the criminal of going up in an opponent's defence, and the clear key of disturbance causes primary disease.Head wound often causes the frightened great fear of patient, " excessive fear leading to sinking of kidney-QI ", and part of the body cavity above the diaphragm housing the heart and lungs mechanism of qi obturation is not smooth, causes sun clearly to sink; " excessive fright leading to disturbance of QI " all gas is therefore lacked of proper care, and body normal physiological activity is suffered momentary upset, and internal organs, the mechanism of qi defended of battalion are unordered in a jumble, thereby produces that headache, dizzy, fatigue and weakness, spirit are uneasy, cardio palmus shape.Moreover, head wound, blood stagnation is in brain, qi and blood stagnation; Or the ailment said due to cold or exposure criminal of going up in an opponent's defence, all can cause headache, dizziness.Finally, fear impairing kidney, but, more makes all disease migrations difficult under kidney essense.
Summary of the invention
The object of the invention is to provide for overcoming above-mentioned technical problem Chinese medicine formula and the preparation method of a kind of eutherapeutic treatment apoplexy and cerebral trauma sequela.
for achieving the above object, the present invention adopts following technical scheme:
Treat a Chinese medicine formula for apoplexy and cerebral trauma sequela, comprise following component by weight:
The Radix Astragali 195 weight portions, Radix Paeoniae Rubra 97.5 weight portions, Radix Angelicae Sinensis 97.5 weight portions, Semen Persicae (stir-fry) 97.5 weight portions, Pheretima 97.5 weight portions, Flos Carthami 39 weight portions, Rhizoma Chuanxiong 65 weight portions, Radix Salviae Miltiorrhizae 195 weight portions, Caulis Spatholobi 130 weight portions, Radix Cyathulae 78 weight portions, Rhizoma Gastrodiae 78 weight portions.
The preparation method of the Chinese medicine formula of described treatment apoplexy and cerebral trauma sequela, comprises the following steps:
(1) above ten a herbs, wash quickly, 60 ℃ of oven dry;
(2) get the Radix Astragali, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Semen Persicae, Pheretima, Flos Carthami, Rhizoma Chuanxiong, Radix Cyathulae, Rhizoma Gastrodiae powder and be broken into fine powder, cross No. five sieves (80 order), mix for subsequent use;
(3) get Radix Salviae Miltiorrhizae, Caulis Spatholobi two taste medicines, are ground into 50 order coarse powder, soak 1 hour, decoct twice.1.5 hours for the first time, 1 hour for the second time, collecting decoction, filtered, and filtrate is concentrated, adds refined honey appropriate, stirs evenly, and obtains concentrated solution for subsequent use;
(4) get the fine powder in step 2, with the concentrated liquid flooding ball in step 3, dry powder capping, 60 ℃ of oven dry, ethane via epoxyethane sterilizing, places 7~10 days, obtains described Chinese medicine formula.
We's syndrome of controlling, hemiplegia, is by due to blood stasis due to qi deficiency.Hemiplegia differential diagnosis in tcm is apoplexy.Liver main air is main store blood again, likes fluent and row catharsis, " institute of heresy gathers, and its gas must be empty ", qi being the governor of blood, assertive evidence apoplexy and hemiplegia, one belong to insufficiency of primordial QI in pathogen it, two to belong to the stagnant meridians of the liver blood stasis of blood not smooth, blood stasis due to qi deficiency is sent out as hemiplegia.Control inrigorating qi and promoting blood circulation to be method.Unit's deficiency of vital energy, therefore side is main by Radix Astragali tonification vigour; Blood stasis belongs to liver, controls wind and first controls blood, therefore compatibility Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Persicae, Radix Paeoniae Rubra, Flos Carthami enter liver, eliminating blood stasis and promoting blood circulation, soothing the liver dispeling the wind; Add Pheretima to invigorate blood circulation and the meridian dredging.Become altogether the agent of collaterals.
We's treating both the principal and secondary aspects of a disease, symptomatic treatment is strong, makes simply, can disposablely produce in enormous quantities, and patent medicine preparation carries taking convenience.
 
The Radix Astragali: its sweet in the mouth, tepor; Return lung, spleen, liver, kidney channel.There is effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be mainly used in treating the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer.
Usage and dosage: decoction 10~30g.When heavy dose of, use 120g.
Special suggestion: table excess pathogen is contained, retention of dampness due to stagnation of QI, food stagnation is stagnated, carbuncle from the beginning of or burst after the excess syndrome such as pyretic toxicity Shang Sheng, and hyperactivity of YANG due to deficiency of YIN person, must prohibit and take this medicine.Anti-Rhizoma et radix veratri (Radix Rhizoma Veratri), fear Oletum Trogopterori, Radix Saposhnikoviae.
Radix Paeoniae Rubra: Radix Paeoniae Rubra bitter in the mouth, cool in nature, there is effect of blood stasis dispelling, pain relieving, removing heat from blood, detumescence.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.The Radix Paeoniae Rubra point excess-heat that can purify the blood, dissipating blood stasis blood is detained.Can only be used for blood system excess-heat, be good at promoting blood circulation to remove blood stasis.Control the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle.For epidemic febrile disease, heat enters nutrient blood, heating, crimson tongue, body and sends out macule, and bleeding due to blood-heat etc.
Radix Angelicae Sinensis: sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and pungent, thus again can promoting the circulation of blood, invigorating middle warmer has, in row, has benefit, is the key medicine in blood.Thereby it can be enriched blood, can invigorate blood circulation again, both can stimulate the menstrual flow, again can be active.All menoxenias, dysmenorrhea, blood deficiency amenorrhea, shallow complexion, weak anemia, metrorrhagia, postnatal blood stasis, example, through women's such as (when menstrual onsets, occur mouth and nose bleed) commonly encountered diseases, can be used angelica for treating. 
Semen Persicae: sweet flat, the bitter in the mouth of property, enters lung, liver, large intestine channel; There is blood stasis removing and clots absorbing, moisturize effect of laxation; Control amenorrhea, dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, traumatic injury, dryness of the intestine constipation.
Pheretima: cold in nature, salty in the mouth.Function: heat clearing away, suppressing the hyperactive liver, Zhichuan, dredging collateral.Return liver, stomach, lung, urinary bladder channel.Function heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, relieving asthma, diuresis, dredging collateral eliminating impediment.Cure mainly high heat agitation, infantile convulsion tic, dyspnea and cough due to lung-heat, accumulation of heat urine retention, arthralgia pain limb fiber crops, hemiplegia, and the card such as sore swollen toxin.Cure mainly height fanatical dry, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, hemiplegia etc.
Flos Carthami: warm in nature, acrid in the mouth, GUIXIN, Liver Channel, function promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.For dysmenorrhea, amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Main apoplexy enters brain headache, arthralgia due to cold, and clonic spasm of the muscle emergency, gold wound, married woman's blood closes loss of fecundity.Have blood-activating and qi-promoting, activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, menoxenia, amenorrhea, dysmenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.
Radix Salviae Miltiorrhizae: bitter in the mouth, micro-pungent, cold nature, the medicine of the heart, spleen, liver, kidney blood system; Cure mainly blood stasis head, breast, the side of body, abdomen pain, gather, menoxenia, dysmenorrhea amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, arthralgia, traumatic injury congestive edema, epidemic febrile disease is vexed, palpitation due to deficiency of blood, sore swollen toxin.
Caulis Spatholobi: meridian distribution of property and flavor: bitter, sweet, temperature.Return liver, kidney channel, red complexion enters blood, and matter profit row is loose; There is relaxing muscles and tendons to promote blood circulation, effect of nourishing blood for regulating menstruation; Cure mainly rheumatic arthralgia, numb hand and foot, quadriplegia, menoxenia, blockage of menstruation, dysmenorrhea, amenorrhea.
Radix Cyathulae: sweet, micro-hardship, property are put down, and dispel the wind, and dampness removing, stimulates the menstrual flow, and invigorates blood circulation.Dispelling the wind and dampness pathogens lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea, lump in the abdomen.For amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.
Rhizoma Gastrodiae: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Rhizoma Gastrodiae conventional with treatment apoplectic hemiplegia, hands and feet caused by paralysis, mouthful glances tiltedly, the disease such as numb limbs and tense tendons, bones and muscles pain, rheumatic arthritis, brain overwork, neurasthenia, insomnia, headache, dizziness, spasm of the limbs, blood fat reducing, blood pressure lowering, alzheimer disease, Parkinson's disease.Have aid yang qi, strong body prolong life, long cloudy fertile strong, mend five kinds of strain and seven kinds of impairment, the effect such as have one's ideas straightened out of promoting blood circulation.
The specific embodiment
Below, in conjunction with example, substantive distinguishing features of the present invention and advantage are further described, but the present invention is not limited to listed embodiment.
Embodiment
Treat a Chinese medicine formula for apoplexy and cerebral trauma sequela, comprise following component by weight:
The Radix Astragali 195 weight portions, Radix Paeoniae Rubra 97.5 weight portions, Radix Angelicae Sinensis 97.5 weight portions, Semen Persicae (stir-fry) 97.5 weight portions, Pheretima 97.5 weight portions, Flos Carthami 39 weight portions, Rhizoma Chuanxiong 65 weight portions, Radix Salviae Miltiorrhizae 195 weight portions, Caulis Spatholobi 130 weight portions, Radix Cyathulae 78 weight portions, Rhizoma Gastrodiae 78 weight portions.
The preparation method of the Chinese medicine formula of described treatment apoplexy and cerebral trauma sequela, comprises the following steps:
(1) above ten a herbs, wash quickly, 60 ℃ of oven dry;
(2) get the Radix Astragali, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Semen Persicae, Pheretima, Flos Carthami, Rhizoma Chuanxiong, Radix Cyathulae, Rhizoma Gastrodiae powder and be broken into fine powder, cross No. five sieves (80 order), mix for subsequent use;
(3) get Radix Salviae Miltiorrhizae, Caulis Spatholobi two taste medicines, are ground into 50 order coarse powder, soak 1 hour, decoct twice.1.5 hours for the first time, one hour for the second time, collecting decoction, filtered, and filtrate is concentrated, adds refined honey appropriate, stirs evenly, and obtains concentrated solution for subsequent use;
(4) get the fine powder in step 2, with the concentrated liquid flooding ball in step 3, dry powder capping, 60 ℃ of oven dry, ethane via epoxyethane sterilizing, places 7~10 days, obtains described Chinese medicine formula, after the assay was approved, and subpackage, 60 weight portion/bottles.
Usage and dosage: each serving with 6~9 weight portions, every day 3 times, 4 weeks is a course for the treatment of, and anemia of pregnant woman is cautious use of.
Clinical data
Give the present invention to 200 routine cerebrovascular sequelae and 200 routine postcerebrotraumatic syndrome patients and treat 4 weeks, contrast (cerebrovascular sequelae is taken BUYANG HUANWU TANG, postcerebrotraumatic syndrome oral western medicine piracetam) is evident in efficacy.Referring to table 1, table 2.
The curative effect for the treatment of cerebrovascular sequelae the present invention and BUYANG HUANWU TANG is relatively in table 1
Group Cure Effectively Do not heal Aggregate efficiency
Treatment group 200 examples (the present invention) 143 42 15 92.5%
Matched group 200 examples (BUYANG HUANWU TANG) 120 25 55 72.5%
Table 1
There were significant differences for 0.01, two group of statistical procedures P <.
The curative effect for the treatment of postcerebrotraumatic syndrome the present invention and piracetam is relatively in table 2
Group Cure Effectively Do not heal Aggregate efficiency
Treatment group 200 examples (the present invention) 30 133 37 81.5%
Matched group 200 examples (piracetam group) 20 121 49 70.5%
Table 2
Statistical procedures x2=6.634, there were significant differences for 0.01, two group of P <.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (2)

1. a Chinese medicine formula for the treatment of apoplexy and cerebral trauma sequela, is characterized in that, comprises following component by weight:
The Radix Astragali 195 weight portions, Radix Paeoniae Rubra 97.5 weight portions, Radix Angelicae Sinensis 97.5 weight portions, Semen Persicae (stir-fry) 97.5 weight portions, Pheretima 97.5 weight portions, Flos Carthami 39 weight portions, Rhizoma Chuanxiong 65 weight portions, Radix Salviae Miltiorrhizae 195 weight portions, Caulis Spatholobi 130 weight portions, Radix Cyathulae 78 weight portions, Rhizoma Gastrodiae 78 weight portions.
2. a preparation method for the treatment of the Chinese medicine formula of apoplexy and cerebral trauma sequela described in claim 1, is characterized in that, comprises the following steps:
(1) above ten a herbs, wash quickly, 60 ℃ of oven dry;
(2) get the Radix Astragali, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Semen Persicae, Pheretima, Flos Carthami, Rhizoma Chuanxiong, Radix Cyathulae, Rhizoma Gastrodiae powder and be broken into fine powder, cross No. five sieves (80 order), mix for subsequent use;
(3) get Radix Salviae Miltiorrhizae, Caulis Spatholobi two taste medicines, are ground into 50 order coarse powder, soak 1 hour, decoct twice; 1.5 hours for the first time, 1 hour for the second time, collecting decoction, filtered, and filtrate is concentrated, adds refined honey appropriate, stirs evenly, and obtains concentrated solution for subsequent use;
(4) get the fine powder in step 2, with the concentrated liquid flooding ball in step 3, dry powder capping, 60 ℃ of oven dry, ethane via epoxyethane sterilizing, places 7~10 days, obtains described Chinese medicine formula.
CN201410101309.XA 2014-03-19 2014-03-19 Traditional Chinese medicine formula for treating stroke and post-traumatic brain syndrome and preparation method of traditional Chinese medicine Pending CN103830591A (en)

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN104721594A (en) * 2015-04-07 2015-06-24 赵克俊 Traditional Chinese medicine for treating systemic brain trauma response syndrome
CN105770501A (en) * 2016-05-18 2016-07-20 高福源 Traditional Chinese medicine capsule for treating post-traumatic brain syndrome and preparation method of traditional Chinese medicine capsule
CN106822611A (en) * 2016-12-28 2017-06-13 华北理工大学 A kind of Chinese medicine composition for nursing postcerebrotraumatic syndrome and preparation method thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104721594A (en) * 2015-04-07 2015-06-24 赵克俊 Traditional Chinese medicine for treating systemic brain trauma response syndrome
CN104721594B (en) * 2015-04-07 2015-11-04 赵克俊 A kind of Chinese medicine for the treatment of cerebral trauma reaction syndrome
CN105770501A (en) * 2016-05-18 2016-07-20 高福源 Traditional Chinese medicine capsule for treating post-traumatic brain syndrome and preparation method of traditional Chinese medicine capsule
CN106822611A (en) * 2016-12-28 2017-06-13 华北理工大学 A kind of Chinese medicine composition for nursing postcerebrotraumatic syndrome and preparation method thereof

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Application publication date: 20140604