CN103478152A - Fenamidone-containing sterilization composition - Google Patents
Fenamidone-containing sterilization composition Download PDFInfo
- Publication number
- CN103478152A CN103478152A CN201210196078.6A CN201210196078A CN103478152A CN 103478152 A CN103478152 A CN 103478152A CN 201210196078 A CN201210196078 A CN 201210196078A CN 103478152 A CN103478152 A CN 103478152A
- Authority
- CN
- China
- Prior art keywords
- fenamidone
- active component
- weight ratio
- test
- propamocarb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000005774 Fenamidone Substances 0.000 title claims abstract description 96
- LMVPQMGRYSRMIW-KRWDZBQOSA-N fenamidone Chemical compound O=C([C@@](C)(N=C1SC)C=2C=CC=CC=2)N1NC1=CC=CC=C1 LMVPQMGRYSRMIW-KRWDZBQOSA-N 0.000 title claims abstract description 96
- 239000000203 mixture Substances 0.000 title claims abstract description 43
- 230000001954 sterilising effect Effects 0.000 title abstract 2
- 238000004659 sterilization and disinfection Methods 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 claims abstract description 38
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 38
- WZZLDXDUQPOXNW-UHFFFAOYSA-N propamocarb Chemical compound CCCOC(=O)NCCCN(C)C WZZLDXDUQPOXNW-UHFFFAOYSA-N 0.000 claims abstract description 25
- 239000005821 Propamocarb Substances 0.000 claims abstract description 24
- LDVVMCZRFWMZSG-OLQVQODUSA-N (3ar,7as)-2-(trichloromethylsulfanyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)Cl)C(=O)[C@H]21 LDVVMCZRFWMZSG-OLQVQODUSA-N 0.000 claims abstract description 23
- 239000005745 Captan Substances 0.000 claims abstract description 23
- 229940117949 captan Drugs 0.000 claims abstract description 23
- 239000005797 Iprovalicarb Substances 0.000 claims abstract description 22
- NWUWYYSKZYIQAE-ZBFHGGJFSA-N L-(R)-iprovalicarb Chemical compound CC(C)OC(=O)N[C@@H](C(C)C)C(=O)N[C@H](C)C1=CC=C(C)C=C1 NWUWYYSKZYIQAE-ZBFHGGJFSA-N 0.000 claims abstract description 22
- 150000003839 salts Chemical class 0.000 claims abstract description 20
- 241000233679 Peronosporaceae Species 0.000 claims description 28
- JHXVRRJXCDAINK-UHFFFAOYSA-N NC(=O)N.N#CC#N Chemical compound NC(=O)N.N#CC#N JHXVRRJXCDAINK-UHFFFAOYSA-N 0.000 claims description 20
- 239000000375 suspending agent Substances 0.000 claims description 20
- 230000000844 anti-bacterial effect Effects 0.000 claims description 18
- 241000233629 Phytophthora parasitica Species 0.000 claims description 14
- 239000000839 emulsion Substances 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 11
- 206010027146 Melanoderma Diseases 0.000 claims description 10
- 241000233614 Phytophthora Species 0.000 claims description 10
- 239000003094 microcapsule Substances 0.000 claims description 10
- 238000009736 wetting Methods 0.000 claims description 10
- 241000221785 Erysiphales Species 0.000 claims description 9
- 239000000725 suspension Substances 0.000 claims description 8
- 239000004530 micro-emulsion Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 206010039509 Scab Diseases 0.000 claims description 5
- 230000035613 defoliation Effects 0.000 claims description 5
- 239000011347 resin Substances 0.000 claims description 5
- 229920005989 resin Polymers 0.000 claims description 5
- 241000607479 Yersinia pestis Species 0.000 claims description 2
- 230000002195 synergetic effect Effects 0.000 abstract description 25
- 230000000694 effects Effects 0.000 abstract description 5
- 239000005747 Chlorothalonil Substances 0.000 abstract description 4
- CRQQGFGUEAVUIL-UHFFFAOYSA-N chlorothalonil Chemical compound ClC1=C(Cl)C(C#N)=C(Cl)C(C#N)=C1Cl CRQQGFGUEAVUIL-UHFFFAOYSA-N 0.000 abstract description 4
- 150000001875 compounds Chemical class 0.000 abstract description 3
- XERJKGMBORTKEO-VZUCSPMQSA-N (1e)-2-(ethylcarbamoylamino)-n-methoxy-2-oxoethanimidoyl cyanide Chemical compound CCNC(=O)NC(=O)C(\C#N)=N\OC XERJKGMBORTKEO-VZUCSPMQSA-N 0.000 abstract description 2
- 239000005756 Cymoxanil Substances 0.000 abstract description 2
- 230000003628 erosive effect Effects 0.000 abstract description 2
- 238000001228 spectrum Methods 0.000 abstract description 2
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 50
- 239000002131 composite material Substances 0.000 description 46
- 239000003814 drug Substances 0.000 description 36
- 230000003449 preventive effect Effects 0.000 description 31
- 239000000575 pesticide Substances 0.000 description 20
- 239000012071 phase Substances 0.000 description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
- 239000013530 defoamer Substances 0.000 description 12
- 239000002270 dispersing agent Substances 0.000 description 12
- 240000008067 Cucumis sativus Species 0.000 description 11
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 11
- 239000008367 deionised water Substances 0.000 description 10
- 229910021641 deionized water Inorganic materials 0.000 description 10
- 231100000820 toxicity test Toxicity 0.000 description 10
- 206010067482 No adverse event Diseases 0.000 description 9
- 230000002528 anti-freeze Effects 0.000 description 9
- 229940079593 drug Drugs 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 239000000080 wetting agent Substances 0.000 description 9
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 8
- 240000003768 Solanum lycopersicum Species 0.000 description 8
- 239000003995 emulsifying agent Substances 0.000 description 8
- 239000002904 solvent Substances 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 239000002562 thickening agent Substances 0.000 description 8
- 230000005764 inhibitory process Effects 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 5
- 238000009472 formulation Methods 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 241000223600 Alternaria Species 0.000 description 4
- 235000010149 Brassica rapa subsp chinensis Nutrition 0.000 description 4
- 235000000536 Brassica rapa subsp pekinensis Nutrition 0.000 description 4
- 241000499436 Brassica rapa subsp. pekinensis Species 0.000 description 4
- 244000183278 Nephelium litchi Species 0.000 description 4
- 241000209140 Triticum Species 0.000 description 4
- 235000021307 Triticum Nutrition 0.000 description 4
- 239000003905 agrochemical Substances 0.000 description 4
- -1 ethylamino- Chemical class 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 206010011732 Cyst Diseases 0.000 description 3
- 241000233622 Phytophthora infestans Species 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 230000010165 autogamy Effects 0.000 description 3
- 239000003899 bactericide agent Substances 0.000 description 3
- 238000000498 ball milling Methods 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 208000031513 cyst Diseases 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 229920002521 macromolecule Polymers 0.000 description 3
- 230000010534 mechanism of action Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 230000002538 fungal effect Effects 0.000 description 2
- 230000000855 fungicidal effect Effects 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 2
- 239000003002 pH adjusting agent Substances 0.000 description 2
- 238000010008 shearing Methods 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- PCCSBWNGDMYFCW-UHFFFAOYSA-N 5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione Chemical compound O=C1C(C)(C=2C=CC(OC=3C=CC=CC=3)=CC=2)OC(=O)N1NC1=CC=CC=C1 PCCSBWNGDMYFCW-UHFFFAOYSA-N 0.000 description 1
- 240000007087 Apium graveolens Species 0.000 description 1
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 description 1
- 235000010591 Appio Nutrition 0.000 description 1
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 240000008415 Lactuca sativa Species 0.000 description 1
- 235000003228 Lactuca sativa Nutrition 0.000 description 1
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 241000233654 Oomycetes Species 0.000 description 1
- MKIMSXGUTQTKJU-UHFFFAOYSA-N Propamocarb hydrochloride Chemical compound [Cl-].CCCOC(=O)NCCC[NH+](C)C MKIMSXGUTQTKJU-UHFFFAOYSA-N 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 239000010242 baoji Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003592 biomimetic effect Effects 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 235000018417 cysteine Nutrition 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 102000006602 glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 description 1
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 150000002460 imidazoles Chemical class 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000003161 proteinsynthetic effect Effects 0.000 description 1
- 229910052704 radon Inorganic materials 0.000 description 1
- SYUHGPGVQRZVTB-UHFFFAOYSA-N radon atom Chemical compound [Rn] SYUHGPGVQRZVTB-UHFFFAOYSA-N 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000004763 spore germination Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/34—Nitriles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A01N47/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing >N—S—C≡(Hal)3 groups
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention discloses a fenamidone-containing sterilization composition, which comprises an active component A and an active component B, wherein the active component A is selected from fenamidone, the active component B is any one compound selected from propamocarb or a salt thereof, cymoxanil, chlorothalonil, captan and iprovalicarb, and a weight ratio of the active component A to the active component B is 1:80-60:1. The composition provides high activities for a plurality of plant diseases of a plurality of crops, and has characteristics of significant synergistic effect, bacterial killing spectrum expanding, low use amount, rainfall erosion resistance, and significant synergy.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest containing Fenamidone.
Technical background
Fenamidone (fenamidone) molecular formula: C
17h
17n
3oS, chemical name: (S)-1-anilino--4-methyl-2-methyl mercapto-4-benzylimidazoline-5-ketone, the mechanism of action of Fenamidone and Famoxate and methoxy acrylic bactericide is similar, shift to suppress the breathing of line runic by state retardance electronics on former side of body level at hydrogenation olive ferment Q mono-cromoci radon, imidazoles bacterium cave (S)-enantiomer specific activity (R)-enantiomer is much higher.
Propamocarb (Propamocarb) chemical name: 3-(dimethylamino) propyl carbamic acid propyl ester, molecular formula: C
9h
21n
2o
2cl.The salt of Propamocarb can be propamocarb (Propamocarb hydrochloride), chemical name: propyl group-3-(dimethylamino) propyl carbamic acid hydrochloride.Propamocarb or its salt all have local systemic action, also can be used as impregnation process and seed protectant.
Frost urea cyanogen (Cymoxanil) chemical name: 2-cyano group-N-[(ethylamino-) carbonyl]-2-(methoxyl group imido grpup) acetamide, molecular formula: C
7h
10n
4o
3, there is contact and local systemic action, can suppress spore germination, effective to downy mildew of garpe, epidemic disease etc., mixed with protective fungicide to extend the lasting period.
Tpn (chlorothalonil) chemical name: daconil M (2,4,5,6-tetrachloro-1,3-benzene dicarbonitrile), molecular formula: C
8cl
4n
2.Tpn can with the fungal cell in glyceraldehyde 3-phosphate dehydro-genase in the combined with protein of cysteine, destroy the metabolism of cell and loss of life power.Its Main Function is the prevention fungal infection, there is no interior suction conduction, but at plant surface, good adhesivity is arranged, and is not subject to rain drop erosion, and the longer drug effect phase is arranged.
Captan (captan) chemical name: 3a, 4,7,7a-tetrahydrochysene-2-(trichloromethyl sulphur)-1H iso-indoles-1,3-(2H)-diketone, molecular formula: C
9h
8cl
3nO
2s.Captan can be prevented and treated the multiple diseases on fruit tree, vegetables, crop, also can be used as seed treatment or fills with root and prevent and treat stem wilt, damping off, black spot.Some kind to apple and pears has poisoning, influential to lettuce, celery, tomato seed.
Iprovalicarb (Iprovalicarb) chemical name: [2-methyl isophthalic acid-[1-(4-aminomethyl phenyl)-ethylamino formoxyl]-propyl group]-carbamyl isopropyl ester, molecular formula: C
18h
28n
2o
3.Iprovalicarb is the amino-acid ester analog derivative, has unique brand-new biomimetic features and makes its mechanism of action be different from the bactericide that other prevent and treat Oomycete.Its mechanism of action is act on fungal cell wall and protein synthetic, can suppress infecting and sprouting of spore, can suppress mycelial growth, causes its distortion, death simultaneously.There is good treatment and eradicant action for Peronosporaceae and the fungus-caused disease of Phytophthora.
In the real process of agricultural production, preventing and treating the problem that disease the most easily produces is the generation of disease drug resistance.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery is mutually composite by Fenamidone and Propamocarb or its salt, white urea cyanogen, tpn, captan, iprovalicarb, good synergistic effect is arranged within the specific limits, and relevant composite about Fenamidone and Propamocarb or its salt, white urea cyanogen, tpn, captan, iprovalicarb, there is not yet relevant report at present at home and abroad.
Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition containing Fenamidone.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition containing Fenamidone, contain active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from Fenamidone, active component B is selected from a kind of in Propamocarb or its salt, white urea cyanogen, tpn, captan, iprovalicarb, and the preferred weight ratio of active components A and active component B is 1 ︰ 60 ~ 40 ︰ 1; More preferably the weight ratio of Fenamidone and Propamocarb or its salt is 1 ︰ 35 ~ 5 ︰ 1, the weight ratio of Fenamidone and white urea cyanogen is 1 ︰ 30 ~ 20 ︰ 1, the weight ratio of Fenamidone and tpn is 1 ︰ 40 ~ 1 ︰ 1, the weight ratio of Fenamidone and captan is 1 ︰ 40 ~ 5 ︰ 1, and the weight ratio of Fenamidone and iprovalicarb is 1 ︰ 30 ~ 20 ︰ 1; The weight ratio that most preferably is Fenamidone and Propamocarb or its salt is 1 ︰ 20 ~ 1 ︰ 1, the weight ratio of Fenamidone and white urea cyanogen is 1 ︰ 10 ~ 10 ︰ 1, the weight ratio of Fenamidone and tpn is 1 ︰ 20 ~ 1 ︰ 1, the weight ratio of Fenamidone and captan is 1 ︰ 20 ~ 1 ︰ 1, and the weight ratio of Fenamidone and iprovalicarb is 1 ︰ 10 ~ 10 ︰ 1.
The described bactericidal composition containing Fenamidone is for the application of the disease of preventing and treating crop, and described crop comprises cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop.
The described bactericidal composition containing Fenamidone is for the application of the disease of preventing and treating crop, and described disease comprises downy mildew, late blight, early blight, black spot, mottled rot disease, damping off, balck shank, powdery mildew, spot defoliation, leaf spot, gray mold, leaf mold, anthracnose, scab, ring spot, resin disease, phytophthora root rot, damping off.
Amount of application when in the present composition, the content of active component depends on independent use, also depend on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target disease.Usually in composition, the weight percentage of active component is gross weight 1%～90%, is preferably 5%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1%～60% active substance by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～80% active substance by weight, is preferably 10%～80%.
At least contain a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water while being beneficial to use.Surface-active contents is 2%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, thickener or defoamer.According to different dosage form, in preparation, can also contain stabilizing agent known in those skilled in the art, antifreeze etc.
Bactericidal composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by processing method known in those skilled in the art preparation, is about to active component and after liquid flux or solid carrier mix, then adds surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
Bactericidal composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent, also can be made into aqua, soluble liquid, soluble powder.
When making wetting powder, composition comprises following component and content: active components A 1% ~ 60%, active component B 1% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
When making water dispersible granules, composition comprises following component and content: active components A 1% ~ 60%, active component B 1% ~ 80%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Comprise following component and content when composition is made suspending agent: active components A 1% ~ 50%, active component B 1% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Comprise following component and content when composition is made suspension emulsion: active components A 1% ~ 50%, active component B 1% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 0 ~ 20%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Comprise following component and content when composition is made microemulsion: active components A 1% ~ 50%, active component B1% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water add to 100%.
Comprise following component and content when composition is made aqueous emulsion: active components A 1% ~ 50%, active component B 1% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single dose; (2) the agricultural chemicals dosage reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) enlarged fungicidal spectrum, multiple diseases has been had to greater activity as downy mildew, late blight, early blight, black spot, mottled rot disease, damping off, balck shank, powdery mildew, spot defoliation, leaf spot, gray mold, leaf mold, anthracnose, scab, ring spot, resin disease, phytophthora root rot, damping off.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment all is weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 18 wetting powder
Fenamidone, active component B, dispersant, wetting agent, filler are mixed, mix in mixed cylinder, mix again after airslide disintegrating mill is pulverized, can be made into wetting powder product of the present invention.Specifically in Table 1.
Table 1 embodiment 1 ~ 18 each component and content
Embodiment 19 ~ 33 water dispersible granules
Fenamidone, active component B, dispersant, wetting agent, disintegrant, binding agent (can add and can not add), filler are obtained to the particle diameter of needs together through air-flow crushing, obtain the materials of granulating.By item quantitatively send in the fluidized bed granulation dryer through granulation and drying after, make water dispersible granules product of the present invention.Specifically in Table 2.
Table 2 embodiment 19 ~ 33 each component and content
Embodiment 34 ~ 50 suspending agents
Dispersant, wetting agent, thickener (can add and can not add), defoamer, antifreeze (can add and can not add) are mixed through high speed shear, add Fenamidone, active component B, supply surplus by deionized water, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent product of the present invention.Specifically in Table 3.
Table 3 embodiment 34 ~ 50 each component and content
Table 1 to Propamocarb in table 3 or its salt, white urea cyanogen, tpn, captan, iprovalicarb exchanged, can make novel formulation.
Embodiment 51 ~ 56 suspension emulsions
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), deionized water are mixed through high speed shear, add Fenamidone, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make the Fenamidone suspending agent, then by active component B, solvent (can add and can not add), emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make suspension emulsion product of the present invention.Specifically in Table 4.
Table 4 embodiment 51 ~ 56 each component and content
White urea cyanogen, tpn, captan, iprovalicarb in table 4 are exchanged, can make novel formulation.
Embodiment 57 ~ 68 aqueous emulsions
Fenamidone, active component B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, become the homogeneous water.Under high-speed stirred, water is added to oil phase, make aqueous emulsion product of the present invention.Specifically in Table 5.
Table 5 example 57 ~ 68 each component and content
Propamocarb in table 5 or its salt, white urea cyanogen, tpn, captan, iprovalicarb are exchanged, can make novel formulation.
Embodiment 69 ~ 71 microemulsions
Fenamidone, active component B are dissolved in the homogenizer that solvent is housed, emulsifier, antifreeze (can add and can not add), defoamer are joined in the homogenizer that above-mentioned solution is housed, give strong the mixing and homogenize after supplying surplus by deionized water, finally obtain the as clear as crystal microemulsion product of the present invention of outward appearance.Specifically in Table 6.
Table 6 embodiment 69 ~ 71 each component and content
Embodiment 72,73 microcapsule suspending agents
By Fenamidone, active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent, dispersant, defoamer, supply surplus by deionized water, bi-material reacts at oil-water interfaces, forms the macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in Table 7.
Table 7 embodiment 72,73 each component and content
Embodiment 74,75 microcapsule suspensions-suspending agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into even oil phase, oil phase is joined in the aqueous phase solution that contains emulsifier, pH adjusting agent under shearing condition, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add Fenamidone, in ball mill, ball milling is 2 ~ 3 hours, make diameter of particle all below 5 μ m, make suspending agent, then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, makes the finely disseminated microcapsule suspension of the present composition-suspending agent product.Specifically in Table 8.
Table 8 embodiment 74,75 each component and content
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect, on this basis, then carry out field trial.
Test method: after the effective inhibition concentration scope of each medicament is determined in prerun, medicament is established respectively 5 dosage by active constituent content and is processed, and establishes the clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament to the crop germ.Measure colony diameter by the right-angled intersection method after 72h, calculate and respectively process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into to probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, with method of least squares, tries to achieve virulence regression equation (y=a+bx), and calculates thus the EC of every kind of medicament
50value.Calculate the different proportioning synergy ratio (SR) of two medicaments according to the Wadley method, SR<0.5 is antagonism simultaneously, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and active component B shared ratio in combination;
A is Fenamidone; B selects a kind of in Propamocarb or its salt, white urea cyanogen, tpn, captan, iprovalicarb.
Application Example two:
For trying disease: tomato blight; Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation; Experimental scheme: effective inhibition concentration scope of determining Fenamidone and Propamocarb or the former medicine of its salt and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to tomato blight of table 9 Fenamidone and Propamocarb or its salt
As shown in Table 9, the proportioning of Fenamidone and Propamocarb or the composite control tomato blight of its salt is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of Fenamidone and Propamocarb or its salt during at 1 ︰ 35 ~ 5 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.20.The optimum ratio of finding Fenamidone and Propamocarb or its salt through test is 5:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:20,1:25,1:30,1:35, especially synergy ratio maximum when Fenamidone and Propamocarb or its salt weight ratio are 1:7, synergistic effect is the most obvious.
Application Example three:
For trying disease: downy mildew of crucifers; Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation; Experimental scheme: effective inhibition concentration scope of determining Fenamidone and the former medicine of white urea cyanogen and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to downy mildew of crucifers of table 10 Fenamidone and white urea cyanogen
As shown in Table 10, the composite proportioning of downy mildew of crucifers of preventing and treating of Fenamidone and white urea cyanogen is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of Fenamidone and white urea cyanogen during at 1 ︰ 30 ~ 20 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.25.The optimum ratio of finding Fenamidone and white urea cyanogen through test is 20:1,15:1,10:1,9:1,8:1,7:1,6:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30, especially synergy ratio maximum when Fenamidone and white urea cyanogen weight ratio are 2:3, synergistic effect is the most obvious.
Application Example four:
For trying disease: downy mildew of garpe; Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation; Experimental scheme: effective inhibition concentration scope of determining the former medicine of Fenamidone and tpn and the two different proportioning mixture through preliminary experiment.
The toxicity test result
Table 11 Fenamidone and the chlorothalonil compound toxicity test analysis of results table to downy mildew of garpe
As shown in Table 11, Fenamidone and chlorothalonil compound are prevented and treated the proportioning of downy mildew of garpe when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of Fenamidone and tpn during at 1 ︰ 40 ~ 1 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.25.The optimum ratio of finding Fenamidone and tpn through test is 1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30,1:35,1:40, especially synergy ratio maximum when Fenamidone and tpn weight ratio are 1:10, synergistic effect is the most obvious.
Application Example five:
For trying disease: potato late blight; Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation; Experimental scheme: effective inhibition concentration scope of determining the former medicine of Fenamidone and captan and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to potato late blight of table 12 Fenamidone and captan
As shown in Table 12, the composite proportioning of potato late blight of preventing and treating of Fenamidone and captan is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of Fenamidone and captan during at 1 ︰ 40 ~ 5 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.15.The optimum ratio of finding Fenamidone and captan through test is 5:1,4:1,3:1,2:1,1:1,1:2,2:5,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20,1:25,1:30,1:35,1:40, especially synergy ratio maximum when Fenamidone and captan weight ratio are 1:8, synergistic effect is the most obvious.
Application Example six:
For trying disease: cucumber downy mildew; Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation; Experimental scheme: effective inhibition concentration scope of determining the former medicine of Fenamidone and iprovalicarb and the two different proportioning mixture through preliminary experiment.
The toxicity test result
The composite analysis of results table of the toxicity test to cucumber downy mildew of table 13 Fenamidone and iprovalicarb
As shown in Table 13, the proportioning of the composite control cucumber downy mildew of Fenamidone and iprovalicarb is when 1 ︰ 80 ~ 60 ︰ 1, synergy ratio SR all is greater than 1.5, illustrate that both are mixed and all show synergistic effect in 1 ︰ 80 ~ 60 ︰ 1 scopes, when the proportioning of Fenamidone and iprovalicarb during at 1 ︰ 30 ~ 20 ︰ 1, synergistic effect is more outstanding, and synergy ratio all is greater than 2.20.Especially synergy ratio maximum when Fenamidone and iprovalicarb weight ratio are 2:3, synergistic effect is the most obvious.
Through test, find: after Fenamidone and active component B are composite, the control of downy mildew, late blight, early blight, black spot, mottled rot disease, damping off, the balck shank, powdery mildew, spot defoliation, leaf spot, gray mold, leaf mold, anthracnose, scab, ring spot, resin disease, phytophthora root rot, damping off is had to obvious synergistic effect, synergy ratio is all more than 1.50.
Test of pesticide effectiveness part
Test medicine is researched and developed, is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.Contrast medicament: 20% Fenamidone suspending agent (autogamy), 35% Propamocarb aqua (commercial), 25% white urea cyanogen wetting powder (autogamy), 75% tpn wetting powder (commercial), 50% captan wetting powder (commercial), 20% iprovalicarb wetting powder (autogamy).
Application Example seven Fenamidones and active component B and the composite control tomato late blight test of pesticide effectiveness thereof
This test arrangement, at the Xian District, Shanxi Province suburban area, is investigated the tomato late blight state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 14 Fenamidone and active component B and the composite control tomato late blight test of pesticide effectiveness thereof
As can be seen from Table 14, after Fenamidone and active component B are composite, can effectively prevent and treat tomato late blight, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example eight Fenamidones and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This test arrangement, in the Jingyang County, Shaanxi Province, is investigated the cucumber downy mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 15 Fenamidone and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 15, after Fenamidone and active component B are composite, can effectively prevent and treat cucumber downy mildew, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example nine Fenamidones and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
This test arrangement, in Weinan City suburb, Shaanxi Province, is investigated the downy mildew of garpe state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 3 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 16 Fenamidone and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 16, after Fenamidone and active component B are composite, can effectively prevent and treat downy mildew of garpe, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten Fenamidones and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This test arrangement, in Weinan City Pucheng County, Shaanxi Province, is investigated the alternaria leaf spot of apple state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 17 Fenamidone and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 17, after Fenamidone and active component B are composite, can effectively prevent and treat alternaria leaf spot of apple, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long, and can treat apple anthracnose, ring spot, and after 14 days, control efficiency is up to more than 97%.In the test scope of medication, the target crop is had no adverse effects.
Application Example 11 Fenamidones and active component B and the composite control wheat powdery mildew test of pesticide effectiveness thereof
This test arrangement, at Shaanxi Province's Weinan City, is investigated the wheat powdery mildew state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 18 Fenamidone and active component B and the composite control wheat powdery mildew test of pesticide effectiveness thereof
As can be seen from Table 18, after Fenamidone and active component B are composite, can effectively prevent and treat wheat powdery mildew, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten diimidazole bacterium ketone and active component B and the composite downy mildew of crucifers test of pesticide effectiveness of preventing and treating thereof
This test arrangement, at the Xian District, Shanxi Province suburban area, is investigated the downy mildew of crucifers state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 19 Fenamidone and active component B and the composite downy mildew of crucifers test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 19, after Fenamidone and active component B are composite, can effectively prevent and treat downy mildew of crucifers, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example 13 Fenamidones and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
This test arrangement, in the Huilai county, Guangdong Province, is investigated the peronophythora litchi state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 20 Fenamidone and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
As can be seen from Table 20, after Fenamidone and active component B are composite, can effectively prevent and treat peronophythora litchi, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten tetramisol bacterium ketone and active component B and the composite control cucumber damping off test of pesticide effectiveness thereof
This test arrangement, in the Jingyang County, Shaanxi Province, is investigated the cucumber damping off state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 21 Fenamidone and active component B and the composite control cucumber damping off test of pesticide effectiveness thereof
As can be seen from Table 21, after Fenamidone and active component B are composite, can effectively prevent and treat the cucumber damping off, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example 15 Fenamidones and active component B and the composite control Chinese cabbage black spot test of pesticide effectiveness thereof
This test arrangement, in Qishan County, Baoji, Shaanxi province city, is investigated the Chinese cabbage black spot state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, once, dispenser is 2 times altogether in dispenser in every 7 days.Within after the last dispenser 7 days, 14 days, 30 days, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 22 Fenamidone and active component B and the composite control Chinese cabbage black spot test of pesticide effectiveness thereof
As can be seen from Table 22, after Fenamidone and active component B are composite, can effectively prevent and treat the Chinese cabbage black spot, control efficiency all is better than the preventive effect of single dose, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
After through different local throughout the country tests, draw, Fenamidone and Propamocarb or its salt, white urea cyanogen, tpn, captan, the composite rear preventive effect to Common Diseases such as the downy mildew on various crop, late blight, early blight, black spot, mottled rot disease, damping off, balck shank, powdery mildew, spot defoliation, leaf spot, gray mold, leaf mold, anthracnose, scab, ring spot, resin disease, phytophthora root rot, damping offs of iprovalicarb are all more than 95%, be better than the single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition containing Fenamidone, it is characterized in that containing active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from Fenamidone, and active component B is selected from a kind of in Propamocarb or its salt, white urea cyanogen, tpn, captan, iprovalicarb.
2. the bactericidal composition containing Fenamidone according to claim 1, it is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 60 ~ 40 ︰ 1.
3. the bactericidal composition containing Fenamidone according to claim 2 is characterized in that:
The weight ratio of Fenamidone and Propamocarb or its salt is 1 ︰ 35 ~ 5 ︰ 1;
The weight ratio of Fenamidone and white urea cyanogen is 1 ︰ 30 ~ 20 ︰ 1;
The weight ratio of Fenamidone and tpn is 1 ︰ 40 ~ 1 ︰ 1;
The weight ratio of Fenamidone and captan is 1 ︰ 40 ~ 5 ︰ 1;
The weight ratio of Fenamidone and iprovalicarb is 1 ︰ 30 ~ 20 ︰ 1.
4. according to the described bactericidal composition containing Fenamidone of any one in claim 1-3, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, microemulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
5. the bactericidal composition containing Fenamidone according to claim 4, for preventing and treating the application of crop pest.
6. application according to claim 5 is characterized in that: described disease comprises downy mildew, late blight, early blight, black spot, mottled rot disease, damping off, balck shank, powdery mildew, spot defoliation, leaf spot, gray mold, leaf mold, anthracnose, scab, ring spot, resin disease, phytophthora root rot, damping off.
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| CN105265439A (en) * | 2014-07-02 | 2016-01-27 | 江苏龙灯化学有限公司 | Method for controlling plant pythium |
| CN108739838A (en) * | 2018-07-19 | 2018-11-06 | 广东广康生化科技股份有限公司 | A kind of efficient bactericidal composite containing folpet and Fenamidone |
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| CN1153454A (en) * | 1994-07-22 | 1997-07-02 | 罗纳-普朗克农业化学公司 | Fungicidal composition including 2-imidazoline-5-one |
| CN1731930A (en) * | 2002-12-06 | 2006-02-08 | 陶氏农业科学公司 | Synergistic compositions |
| CN101541173A (en) * | 2006-12-22 | 2009-09-23 | 拜尔农作物科学股份公司 | Pesticidal composition comprising fenamidone and an insecticide compound |
| WO2010069763A2 (en) * | 2008-12-16 | 2010-06-24 | Basf Se | Synergistic fungicidal mixtures |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1515153A (en) * | 1997-12-02 | 2004-07-28 | 罗纳-普朗克农业化学公司 | Fungicide composition containing 2-imidazoline-5-ketone |
| ATE282311T1 (en) * | 1999-01-29 | 2004-12-15 | Basf Ag | AQUEOUS SUSPENSION CONCENTRATE |
| DE19904081A1 (en) * | 1999-02-02 | 2000-08-03 | Bayer Ag | Fungicidal active ingredient combinations |
-
2012
- 2012-06-14 CN CN201610651764.6A patent/CN106259347A/en active Pending
- 2012-06-14 CN CN201210196078.6A patent/CN103478152B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1153454A (en) * | 1994-07-22 | 1997-07-02 | 罗纳-普朗克农业化学公司 | Fungicidal composition including 2-imidazoline-5-one |
| CN1731930A (en) * | 2002-12-06 | 2006-02-08 | 陶氏农业科学公司 | Synergistic compositions |
| CN101541173A (en) * | 2006-12-22 | 2009-09-23 | 拜尔农作物科学股份公司 | Pesticidal composition comprising fenamidone and an insecticide compound |
| WO2010069763A2 (en) * | 2008-12-16 | 2010-06-24 | Basf Se | Synergistic fungicidal mixtures |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105265439A (en) * | 2014-07-02 | 2016-01-27 | 江苏龙灯化学有限公司 | Method for controlling plant pythium |
| CN108184855A (en) * | 2014-07-02 | 2018-06-22 | 江苏龙灯化学有限公司 | A kind of method for preventing and kill off plant pythium spp |
| CN108739838A (en) * | 2018-07-19 | 2018-11-06 | 广东广康生化科技股份有限公司 | A kind of efficient bactericidal composite containing folpet and Fenamidone |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106259347A (en) | 2017-01-04 |
| CN103478152B (en) | 2017-02-15 |
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Address after: 715500 Pucheng high tech Industrial Development Zone, Weinan, Shaanxi Patentee after: SHAANXI MEIBANG PHARMACEUTICAL GROUP Co.,Ltd. Address before: 715500 Shaanxi Pucheng Weinan County agricultural base industrial park Patentee before: Shaanxi Meibang pesticide Co.,Ltd. |
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