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CN103238636A - Environment-friendly special air conditioner disinfectant and preparation method thereof - Google Patents

Environment-friendly special air conditioner disinfectant and preparation method thereof Download PDF

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Publication number
CN103238636A
CN103238636A CN2013101971605A CN201310197160A CN103238636A CN 103238636 A CN103238636 A CN 103238636A CN 2013101971605 A CN2013101971605 A CN 2013101971605A CN 201310197160 A CN201310197160 A CN 201310197160A CN 103238636 A CN103238636 A CN 103238636A
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China
Prior art keywords
weight portion
polihexanide
synergist
disinfectant
environment
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Pending
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CN2013101971605A
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Chinese (zh)
Inventor
张润梅
邸诗雨
苏林东
赵胜美
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XI'AN YIWEI PUTAI INDUSTRY TRADE Co Ltd
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XI'AN YIWEI PUTAI INDUSTRY TRADE Co Ltd
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Priority to CN2013101971605A priority Critical patent/CN103238636A/en
Publication of CN103238636A publication Critical patent/CN103238636A/en
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Abstract

The invention relates to an environment-friendly special air conditioner disinfectant and a preparation method thereof. The existing disinfectant products used for disinfecting and sterilizing air conditioners are traditional disinfectant, which has large irritative odor and is liable to pollute the indoor environment, and the products have strong antibacterial ability while weak disinfection and sterilization ability to fail to meet the cleaning and sterilizing regulation demands of air conditioner ventilating systems. The preparation method comprises the following steps: adding a synergist (triclosan) in ethanol, and fully stirring the synergist in a sealed condition to completely dissolve the same; adding a mixture of polihexanide and synergist or polihexanide in water to completely dissolve the same; and adding peppermint essential oil in the mixture, and uniformly stirring the mixture to obtain the target product. The synergist (triclosan) adopted in the invention can be used for effectively overcoming the defects of strong antibacterial ability and weak disinfection and sterilization ability of polihexanide, greatly improving the disinfection and sterilization ability of polihexanide, reducing the dosage of polihexanide, lowering the production cost and keeping the environmental friendliness of polihexanide.

Description

Environment-friendly type air-conditioning appropriative disinfector and preparation method thereof
Technical field
The present invention relates to a kind of disinfectant, be specifically related to a kind of environment-friendly type air-conditioning appropriative disinfector and preparation method thereof.
Background technology
Air-conditioning is after shelving for a long time or using for a long time, and it is inner to stop up dust, dirt and bacterium easily, produces strange taste, occurs that refrigeration descends, power consumption increases, degradation problems under the air output, and allows the people suffer from " air conditioner disease " easily.So-called air conditioner disease, a kind of air conditioner comprehensive disease due to referring to rest under the air conditioner surroundings for a long time, mainly show as symptoms such as uncomfortable in chest, dizzy, nauseating, weak, arthralgia, appetite decline, failure of memory, nasal obstruction, tinnitus, some is also with low-heat, and irregular menstruation may appear in the women.One big inducement of air conditioner disease is exactly " microorganism is caused a disease ", and this sick root that produces just is that thereby without cleaning in the gas that in air-conditioning blows out do not contain a large amount of bacteriums, fungi, cause respiratory disease for a long time by use or the long-time back of using for air-conditioning.
The disinfectant products that is used for the Air conditioner sterilizing sterilization at present is traditional disinfectant, and penetrating odor is bigger, pollutes indoor environment easily, and this series products antibacterial ability is strong, a little less than the disinfection ability, can not satisfy air conditioner ventilating system cleaning and sterilizing code requirement.
Summary of the invention
The purpose of this invention is to provide environment-friendly type air-conditioning appropriative disinfector of noresidue behind a kind of disinfection efficient height, the disinfection and preparation method thereof.
The technical solution adopted in the present invention is:
Environment-friendly type air-conditioning appropriative disinfector is characterized in that:
Component by following weight portion is made:
0.05-0.1 weight portion synergist trichlorine sand;
The 30-40 parts by weight of ethanol;
0.1-1 weight portion polihexanide;
0.01 weight portion peppermint essential oil;
The water of 59-70 weight portion.
The Matsubain in the last of the ten Heavenly stems that also includes the 0.15-0.5 weight portion in the prescription.
The preparation method of environment-friendly type air-conditioning appropriative disinfector is characterized in that:
Realized by following steps:
Step 1: the synergist trichlorine sand of 0.05-0.1 weight portion is added in the ethanol of 30-40 weight portion, and fully stirring is dissolved it fully under air-proof condition;
Step 2: with the polihexanide of 0.1-1 weight portion and 0.15-0.5 weight portion the last of the ten Heavenly stems Matsubain mixture or 0.1-1 weight portion polihexanide, add in the 59-70 weight parts water that measures to dissolving fully;
Step 3: step 1 gained solution is joined in the step 2 gained solution, adds the peppermint essential oil of 0.01 weight portion again, mix the purpose product.
The present invention has the following advantages:
The synergist trichlorine sand that uses among the present invention, overcome effectively that the polihexanide antibacterial ability is strong, the shortcoming of sterilization ability, significantly improved the disinfection ability of polihexanide, reduced the polihexanide usage amount, reduce production cost, kept the environment friendly of polihexanide, namely colourless, tasteless, non-volatile, do not contain, harmful substance poisonous to human body and environment, all kinds of material surfaces are disinfected free from corrosion advantage.The air-conditioning appropriative disinfector that the present invention makes, through 37 ℃ of samples of depositing 3 months, the rate of descent of its bactericidal active ingredient only is 0.8%.
Embodiment
The present invention will be described in detail below in conjunction with embodiment.
The preparation method of environment-friendly type air-conditioning appropriative disinfector involved in the present invention, realized by following steps:
Step 1: the synergist trichlorine sand of 0.05-0.1 weight portion is added in the ethanol of 30-40 weight portion, and fully stirring is dissolved it fully under air-proof condition;
Step 2: with the polihexanide of 0.1-1 weight portion and 0.15-0.5 weight portion the last of the ten Heavenly stems Matsubain mixture or 0.1-1 weight portion polihexanide, add in the 59-70 weight parts water that measures to dissolving fully;
Step 3: step 1 gained solution is joined in the step 2 gained solution, adds the peppermint essential oil of 0.01 weight portion again, mix the purpose product.
Embodiment 1:
Step 1: the synergist trichlorine sand of 0.05 weight portion is added in the ethanol of 30 weight portions, and fully stirring is dissolved it fully under air-proof condition;
Step 2: with 0.1 weight portion polihexanide, add in 59 weight parts waters that measure to dissolving fully;
Step 3: step 1 gained solution is joined in the step 2 gained solution, adds the peppermint essential oil of 0.01 weight portion again, mix the purpose product.
Embodiment 2:
Step 1: the synergist trichlorine sand of 0.06 weight portion is added in the ethanol of 33 weight portions, and fully stirring is dissolved it fully under air-proof condition;
Step 2: with 1 weight portion polihexanide, add in 63 parts of water that measure to dissolving fully;
Step 3: step 1 gained solution is joined in the step 2 gained solution, adds the peppermint essential oil of 0.01 weight portion again, mix the purpose product.
Embodiment 3:
Step 1: the synergist trichlorine sand of 0.08 weight portion is added in the ethanol of 36 weight portions, and fully stirring is dissolved it fully under air-proof condition;
Step 2: with the polihexanide of 0.1 weight portion and 0.15 weight portion the last of the ten Heavenly stems Matsubain mixture, add in 67 parts of water that measure to dissolving fully;
Step 3: step 1 gained solution is joined in the step 2 gained solution, adds the peppermint essential oil of 0.01 weight portion again, mix the purpose product.
Embodiment 4:
Step 1: the synergist trichlorine sand of 0.1 weight portion is added in the ethanol of 40 weight portions, and fully stirring is dissolved it fully under air-proof condition;
Step 2: with the polihexanide of 1 weight portion and 0.5 weight portion the last of the ten Heavenly stems Matsubain mixture, add in 70 parts of water that measure to dissolving fully;
Step 3: step 1 gained solution is joined in the step 2 gained solution, adds the peppermint essential oil of 0.01 weight portion again, mix the purpose product.
The present invention uses the novel environment-friendly high molecular polymer, compound synergic agent, solubilizer and have the composite disinfectant that the composite complexing of Chinese herbal medicine extract of disinfective action forms, sterilization wide spectrum, efficient, nontoxic.As effective composition 200mg/L polihexanide effect 5min, staphylococcus aureus, pseudomonas aeruginosa, Escherichia coli are killed logarithm value all reach more than 5.0; Active ingredient 400mg/L polihexanide to the oidiomycetic logarithm value of killing of white greater than 5.0.Acute oral toxicity test after the mouse contamination, poisoning symptom and death do not occur, male and female its mouse oral LD50>5000mg/kg body weight, the nontoxic level in the true border of this disinfectant.Rabbit skin irritant test, disinfectant is 0 to skin irritatin reaction integral mean value, shows that this disinfectant is to the true border of rabbit skin nonirritant.Cumulative toxicity test, administration 20 days, death does not appear in mouse, cumulative coefficient k>5, disinfectant is no cumulative toxicity.The skin allergic reaction test, experimental group cavy sensitization rate is 0%, does not see skin allergic reaction, illustrates that this disinfectant does not have sensitization.Experiment shows: this disinfectant is compared with traditional skin antiseptic, and effectively working concentration is low, good stability, and nontoxic, non-stimulated, no mutagenesis, no cumulative toxicity does not cause allergy.
Performance Detection process and the experimental data of the air-conditioning appropriative disinfector that the present invention is prepared:
For understanding the Disinfection Effect of air-conditioning appropriative disinfector, carried out experimental observation, the result is as follows:
1 method
1.1 the test preparation of bacteria suspension
Staphylococcus aureus (ATCC 6538), Escherichia coli 8099, pseudomonas aeruginosa (ATCC 15442) and the fresh slant culture of Candida albicans (ATCC 10231) 24hr are washed and are diluted to bacteria suspension with dilution, with the dilution of opposing doubly of 3% bSA solution, make the test bacteria suspension.
1.2 neutralizer is selected test
6 groups if (table 1).L group asepsis growth or bacterium number are far fewer than the 2nd group, and when the 2nd group of bacterium number surpassed 50cfu/ml, the 3rd, 4,5 group of bacterium number differed and be no more than 15%, the 6 group of asepsis growth, show that selected neutralizer and concentration thereof are suitable.
1.3 suspension quantitative disinfecting test
During test, each disinfectant is mixed with the thimerosal of 1.25 times of experimental concentration with aseptic hard water.3% bovine serum albumin(BSA) is added bacterium liquid, make that albuminous percent by volume is 50% in the bacteria suspension, lm bacterium liquid is added in the 4ml thimerosal, as experimental group, replace thimerosal with dilution, add people's bacteria suspension, as positive control, the sampling of effect certain hour, neutralization, the inoculation plate is cultivated, the counting bacterium colony calculates and kills logarithm value.
2.1 neutralizer result of the test
Test shows that with the neutralizer that contains 6g/L sodium thiosulfate, 2.5g/L sodium sulphite, 7g/L lecithin, 5g/L tween composition, effectively the disinfectant of neutralization test concentration all reaches institute's provisioning request (table 1).
Table l air-conditioning appropriative disinfector neutralization test result
Figure 2013101971605100002DEST_PATH_IMAGE002
2.2 bactericidal effect
Test shows, by synergist and (polihexanide+last of the ten Heavenly stems Matsubain) and the composite air-conditioning appropriative disinfector of peppermint essential oil, acts on 1min, staphylococcus aureus, pseudomonas aeruginosa, Escherichia coli killed logarithm value all reach more than 5.00; Effect 3min kills logarithm value greater than 5.00 to what white was read coccus.By synergist and polihexanide and the composite air-conditioning appropriative disinfector of peppermint essential oil, effect 3min, to staphylococcus aureus, pseudomonas aeruginosa, the colibacillary logarithm value of killing greater than 5.00; The oidiomycetic logarithm value of killing of the effect white of 5min is greater than 5.00.By synergist and the last of the ten Heavenly stems Matsubain and the composite air-conditioning appropriative disinfector of peppermint essential oil, effect 5min, staphylococcus aureus, pseudomonas aeruginosa, the colibacillary logarithm value of killing are reached more than 5.00, pseudomonas aeruginosa, Escherichia coli are killed logarithm value reach more than 4.00; Effect 5min only reaches more than 3.00 the oidiomycetic logarithm value of killing of white.The result shows: by the composite air-conditioning appropriative disinfector of synergist and (polihexanide+last of the ten Heavenly stems Matsubain) and peppermint essential oil prescription and by the composite air-conditioning appropriative disinfector of synergist and polihexanide and peppermint essential oil prescription, all staphylococcus aureus, pseudomonas aeruginosa, Escherichia coli and Candida albicans are all had good bactericidal action, and the former is better than the latter.All meet Ministry of Public Health's disinfection technology standard (table 2).
Table 2 air-conditioning appropriative disinfector is to the killing effect of microorganism
The present invention's " synergist and (polihexanide+last of the ten Heavenly stems Matsubain)+peppermint essential oil " prescription is detected according to the regulation in Ministry of Public Health's " disinfection technology standard " through Disease Control and Prevention Center toxicity chamber:
(1) acute oral toxicity test after the mouse contamination, poisoning symptom and death do not occur, male and female its mouse oral LD50>5000mg/kg body weight, the nontoxic level in the true border of this disinfectant.
(2) rabbit skin irritant test, disinfectant is 0 to skin irritatin reaction integral mean value, shows that this disinfectant is to the true border of rabbit skin nonirritant.
(3) cumulative toxicity test, administration 20 days, death does not appear in mouse, cumulative coefficient k>5, disinfectant is no cumulative toxicity.
(4) skin allergic reaction test, experimental group cavy sensitization rate is 0%, does not see skin allergic reaction, illustrates that this disinfectant does not have sensitization.
It is cited that content of the present invention is not limited to embodiment, and the conversion of any equivalence that those of ordinary skills take technical solution of the present invention by reading specification of the present invention is claim of the present invention and contains.

Claims (3)

1. environment-friendly type air-conditioning appropriative disinfector is characterized in that:
Component by following weight portion is made:
0.05-0.1 weight portion synergist trichlorine sand;
The 30-40 parts by weight of ethanol;
0.1-1 weight portion polihexanide;
0.01 weight portion peppermint essential oil;
The water of 59-70 weight portion.
2. environment-friendly type air-conditioning appropriative disinfector according to claim 1 is characterized in that:
The Matsubain in the last of the ten Heavenly stems that also includes the 0.15-0.5 weight portion in the prescription.
3. the preparation method of environment-friendly type air-conditioning appropriative disinfector is characterized in that:
Realized by following steps:
Step 1: the synergist trichlorine sand of 0.05-0.1 weight portion is added in the ethanol of 30-40 weight portion, and fully stirring is dissolved it fully under air-proof condition;
Step 2: with the polihexanide of 0.1-1 weight portion and 0.15-0.5 weight portion the last of the ten Heavenly stems Matsubain mixture or 0.1-1 weight portion polihexanide, add in the 59-70 weight parts water that measures to dissolving fully;
Step 3: step 1 gained solution is joined in the step 2 gained solution, adds the peppermint essential oil of 0.01 weight portion again, mix the purpose product.
CN2013101971605A 2013-05-24 2013-05-24 Environment-friendly special air conditioner disinfectant and preparation method thereof Pending CN103238636A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105309473A (en) * 2014-06-06 2016-02-10 上海番安机电安装工程有限公司 Disinfecting liquid for water curtain air coolers or central air conditioners
CN107603752B (en) * 2017-08-31 2021-03-23 广州净亮科技有限公司 Air conditioner cleaning agent with degerming effect

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101028530A (en) * 2006-02-27 2007-09-05 权力敏 Air antiseptic cleaner
CN101518658A (en) * 2009-04-01 2009-09-02 天津美真泰克化工有限公司 Effervescence preparation composition used for sanitary towel and preparation method and application thereof
CN101812383A (en) * 2010-05-20 2010-08-25 北京绿伞化学股份有限公司 Disinfecting detergent and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101028530A (en) * 2006-02-27 2007-09-05 权力敏 Air antiseptic cleaner
CN101518658A (en) * 2009-04-01 2009-09-02 天津美真泰克化工有限公司 Effervescence preparation composition used for sanitary towel and preparation method and application thereof
CN101812383A (en) * 2010-05-20 2010-08-25 北京绿伞化学股份有限公司 Disinfecting detergent and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105309473A (en) * 2014-06-06 2016-02-10 上海番安机电安装工程有限公司 Disinfecting liquid for water curtain air coolers or central air conditioners
CN107603752B (en) * 2017-08-31 2021-03-23 广州净亮科技有限公司 Air conditioner cleaning agent with degerming effect

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Application publication date: 20130814