CN102872078B - Application of Houttuynoid C in drugs for treating leukemia - Google Patents
Application of Houttuynoid C in drugs for treating leukemia Download PDFInfo
- Publication number
- CN102872078B CN102872078B CN 201210417571 CN201210417571A CN102872078B CN 102872078 B CN102872078 B CN 102872078B CN 201210417571 CN201210417571 CN 201210417571 CN 201210417571 A CN201210417571 A CN 201210417571A CN 102872078 B CN102872078 B CN 102872078B
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- Prior art keywords
- houttuynoid
- leukemia
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- drugs
- cell
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- 208000032839 leukemia Diseases 0.000 title claims abstract description 26
- 239000003814 drug Substances 0.000 title claims abstract description 16
- FCUIRBQXJWMGLZ-YLUJEXTNSA-N 2-(3-decanoyl-7-hydroxy-1-benzofuran-4-yl)-5,7-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one Chemical compound C=12C(C(=O)CCCCCCCCC)=COC2=C(O)C=CC=1C=1OC2=CC(O)=CC(O)=C2C(=O)C=1O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O FCUIRBQXJWMGLZ-YLUJEXTNSA-N 0.000 title abstract description 62
- 229940079593 drug Drugs 0.000 title abstract 7
- 150000001875 compounds Chemical class 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 11
- 229930190556 houttuynoid Natural products 0.000 claims description 4
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- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 20
- 230000000694 effects Effects 0.000 description 5
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- 208000009889 Herpes Simplex Diseases 0.000 description 4
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- 241000700584 Simplexvirus Species 0.000 description 4
- 230000003602 anti-herpes Effects 0.000 description 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 240000000691 Houttuynia cordata Species 0.000 description 3
- 235000013719 Houttuynia cordata Nutrition 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 229930003935 flavonoid Natural products 0.000 description 3
- 150000002215 flavonoids Chemical class 0.000 description 3
- 235000017173 flavonoids Nutrition 0.000 description 3
- 238000000684 flow cytometry Methods 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 239000013642 negative control Substances 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 206010000830 Acute leukaemia Diseases 0.000 description 2
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical group [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
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- 239000008280 blood Substances 0.000 description 2
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- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- KZDCMKVLEYCGQX-UDPGNSCCSA-N 2-(diethylamino)ethyl 4-aminobenzoate;(2s,5r,6r)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;hydrate Chemical compound O.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1.N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 KZDCMKVLEYCGQX-UDPGNSCCSA-N 0.000 description 1
- 208000036762 Acute promyelocytic leukaemia Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
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- 229920002472 Starch Polymers 0.000 description 1
- -1 Tetramethyl azo azoles salt Chemical class 0.000 description 1
- GLNADSQYFUSGOU-GPTZEZBUSA-J Trypan blue Chemical compound [Na+].[Na+].[Na+].[Na+].C1=C(S([O-])(=O)=O)C=C2C=C(S([O-])(=O)=O)C(/N=N/C3=CC=C(C=C3C)C=3C=C(C(=CC=3)\N=N\C=3C(=CC4=CC(=CC(N)=C4C=3O)S([O-])(=O)=O)S([O-])(=O)=O)C)=C(O)C2=C1N GLNADSQYFUSGOU-GPTZEZBUSA-J 0.000 description 1
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- 229940127219 anticoagulant drug Drugs 0.000 description 1
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- 210000001185 bone marrow Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
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- 238000000556 factor analysis Methods 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 description 1
- 229960001008 heparin sodium Drugs 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000005087 mononuclear cell Anatomy 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- MYFATKRONKHHQL-UHFFFAOYSA-N rhodamine 123 Chemical compound [Cl-].COC(=O)C1=CC=CC=C1C1=C2C=CC(=[NH2+])C=C2OC2=CC(N)=CC=C21 MYFATKRONKHHQL-UHFFFAOYSA-N 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210417571 CN102872078B (en) | 2012-10-27 | 2012-10-27 | Application of Houttuynoid C in drugs for treating leukemia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210417571 CN102872078B (en) | 2012-10-27 | 2012-10-27 | Application of Houttuynoid C in drugs for treating leukemia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102872078A CN102872078A (en) | 2013-01-16 |
| CN102872078B true CN102872078B (en) | 2013-07-17 |
Family
ID=47473749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210417571 Active CN102872078B (en) | 2012-10-27 | 2012-10-27 | Application of Houttuynoid C in drugs for treating leukemia |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102872078B (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2004069233A1 (en) * | 2003-02-04 | 2006-05-25 | 株式会社ヤクルト本社 | Breast cancer resistance protein inhibitor |
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2012
- 2012-10-27 CN CN 201210417571 patent/CN102872078B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN102872078A (en) | 2013-01-16 |
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Owner name: NANTONG SHIJIN INDUSTRY CO., LTD. Free format text: FORMER OWNER: WU JUNHUA Effective date: 20130828 |
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Free format text: CORRECT: ADDRESS; FROM: 210009 NANJING, JIANGSU PROVINCE TO: 226000 NANTONG, JIANGSU PROVINCE |
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Effective date of registration: 20130828 Address after: 226000 Century Avenue, Tongzhou Economic Development Zone, Jiangsu, China, No. 197, No. Patentee after: Nantong International Industrial Co.,Ltd. Address before: 210009 No. 22, Hankou Road, Gulou District, Jiangsu, Nanjing Patentee before: Wu Junhua |
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Effective date of registration: 20170401 Address after: 226300 Nantong high tech Zone, Jiangsu province Jinqiao West Road, No. 8, No. Patentee after: JIANGSU MEIZHONG MEDICAL TECHNOLOGY Co.,Ltd. Address before: 226000 Century Avenue, Tongzhou Economic Development Zone, Jiangsu, China, No. 197, No. Patentee before: Nantong International Industrial Co.,Ltd. |
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Effective date of registration: 20230720 Address after: 222, A2 Building, Jianghai Zhihui Park, 1188 New Century Avenue, Nantong Hi tech Industrial Development Zone, Jiangsu Province, 226000 Patentee after: Nantong San Intellectual Property Service Co.,Ltd. Address before: 226300 No.8, Jinqiao West Road, Nantong high tech Zone, Nantong City, Jiangsu Province Patentee before: JIANGSU MEIZHONG MEDICAL TECHNOLOGY Co.,Ltd. |
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Application publication date: 20130116 Assignee: Jiangsu Yichuang Packaging Materials Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048413 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Jingxuan Textile Technology Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048319 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231127 Application publication date: 20130116 Assignee: Nantong Huanlian Textile Technology Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048315 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231127 Application publication date: 20130116 Assignee: Nantong Huase Space Textile Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048606 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Anergu New Material Technology Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048605 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Laiou Electronic Technology Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048604 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Yitong Intelligent Control Technology (Nantong) Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048603 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Ouchen Electronic Technology Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048602 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Laishang Electronic Technology Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048601 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Lingde Pharmaceutical Equipment Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048600 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Chujie Electronic Equipment Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048597 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Jiaerjie Labor Care Products Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048596 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: JIANGSU KANGFEITE POWER TECHNOLOGY Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048594 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Tuoerpu Surveying and Mapping Information Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048583 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong TongZhou Jinfeng Textile Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048582 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong Weiai Home Textile Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048563 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Qiju Textile Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048556 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong Juguang Trading Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048551 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong Chenghui Pharmacy Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048548 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong Tongzhou Kangxintang Drugstore Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048542 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong Tuanpinhui E-commerce Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048537 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong Koushun E-commerce Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048506 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong Tuoda Machinery Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048494 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Weizhi New Material Technology (Nantong) Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048487 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: NANTONG FEIHAI ELECTRONIC TECHNOLOGY CO.,LTD. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048483 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Haoshi new material technology Nantong Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048475 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: Nantong Steel Machinery Manufacturing Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048466 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231128 Application publication date: 20130116 Assignee: NANTONG YUQI METAL PRODUCTS Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048459 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: NANTONG KYLIN MACHINERY LTD. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048456 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: NANTONG LILIAN MACHINE TOOL MANUFACTURING CO.,LTD. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048450 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Yuma Electromechanical Manufacturing Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048446 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Dongdong Steel Structure Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048444 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Huaxin Price Evaluation Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048443 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Yaocheng mechanical equipment manufacturing Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048440 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 Application publication date: 20130116 Assignee: Nantong Xinxin Pharmaceutical Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048425 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231129 |
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Application publication date: 20130116 Assignee: Nantong Yijialai Woolen Knitting Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980049377 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: NANTONG BEITE PHARMACEUTICAL MACHINERY Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980049199 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: NANTONG HAIGUO MACHINERY Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980049196 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: Nantong Qiaojiang packaging materials Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980049191 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: Nantong Bairun Catering Management Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980049185 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: Nantong Nongchaoer Food Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048976 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: Xingren Tank Farm of Nantong Xinhai Liquefied Gas Service Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048969 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: NANTONG SHUANGHE FOOD Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048967 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: Jiangsu guanan electromechanical Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048961 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: Nantong Runyuan structural parts Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048952 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231203 Application publication date: 20130116 Assignee: Nantong Jinbao Machinery Manufacturing Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048947 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231202 Application publication date: 20130116 Assignee: Nantong Juntai motor vehicle testing Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048942 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231202 Application publication date: 20130116 Assignee: Honglei mechanical equipment (Nantong) Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048782 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231202 Application publication date: 20130116 Assignee: American Antelope Home Textile (Nantong) Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048774 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231202 Application publication date: 20130116 Assignee: Nantong Ansheng Textile Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048765 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231130 Application publication date: 20130116 Assignee: NANTONG YA TAI CANDLE ARTS & CRAFTS Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048764 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231130 Application publication date: 20130116 Assignee: Nantong Jianwei Metal Technology Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048759 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231202 Application publication date: 20130116 Assignee: JIANGSU YATAI FITNESS CO.,LTD. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980048748 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231202 |
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Application publication date: 20130116 Assignee: Nantong Zhili Machinery Technology Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2023980049698 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20231205 |
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Application publication date: 20130116 Assignee: JIANGSU HAOHAN INFORMATION TECHNOLOGY Co.,Ltd. Assignor: Nantong San Intellectual Property Service Co.,Ltd. Contract record no.: X2024980003183 Denomination of invention: The application of Houttuynoid C in the treatment of leukemia drugs Granted publication date: 20130717 License type: Common License Record date: 20240322 |
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