CN102525593B - Clamp control unit and clamp unit matched with same - Google Patents
Clamp control unit and clamp unit matched with same Download PDFInfo
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- CN102525593B CN102525593B CN201210018324.9A CN201210018324A CN102525593B CN 102525593 B CN102525593 B CN 102525593B CN 201210018324 A CN201210018324 A CN 201210018324A CN 102525593 B CN102525593 B CN 102525593B
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- clip
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- clamping limb
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/122—Clamps or clips, e.g. for the umbilical cord
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/128—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips
- A61B17/1285—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips for minimally invasive surgery
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Clamps And Clips (AREA)
Abstract
The invention discloses a clamp control unit and a clamp unit matched with the same. The clamp control unit comprises an outer sheath tube, a spiral sheath tube and an operation screw which are successively in sleeve connection from the outside to the inside, wherein the spiral sheath tube has a close end and a far end, more than one section of through groove is arranged at the far end along the circumferential direction, the outer sheath tube and the operation screw can both axially move along the spiral sheath tube, a clamp arm is arranged at the far end of the operation screw, the clamp arm can elastically open in a natural state, and the clamp arm can close when affected by radial constrains. The clamp control unit and the clamp unit matched with the clamp control unit have the advantages that the clamp control unit can control movement and rotation of a clamp and is accurate and reliable in control, the clamp unit is ideal in clamping effect, and the clamp can be opened again when is closed.
Description
Technical field
The present invention relates to a kind of to digestive tract hemorrhage disease carry out stopping blooding process or vascular, tissue etc. are closed, the device of fixing process, particularly relate to a kind of induction system coordinating Endoscope-assisted pipeline and there is flexible insertion sections accordingly, arrive digestive tract hemorrhage disease adjacent tissue and the clip control unit of clipping hemostasis operation carried out to pathological tissues and is mated the clip unit of use.
Background technology
At present, the clip induction system that known cooperation Endoscope-assisted pipeline uses can be divided into reusable and single use two kinds of devices, it all can realize the expanding-contracting action of operation silk in helical sheath pipe, and some induction systems can also realize the spinning movement of operation silk in helical sheath pipe.What some products adopted when being disconnected from induction system by clip is break process, and what also have some products to adopt is some other disrupted configuration.Though clip can close by Resolution Clip as Boston company after opening again, the induction system of this product is disposable equipment, and can not realize the spinfunction of clip, at cost, functionally there is significant limitation.Consider that doctor may occur the situation that clamping effect is undesirable in the process of clamping disease tissue, can reopen after clip closes is a very practical function.
Summary of the invention
The technical problem to be solved in the present invention is that existing reusable clip induction system can not ensure that rear Reclosable opened by clip.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of clip control unit, comprises the outer sheath, helical sheath pipe and the operation silk that are socketed in turn from outside to inside; Helical sheath pipe has near-end and far-end, and its far-end is along the circumferential direction provided with the rotation groove of more than a section; Outer sheath and operation silk all can moving axially along helical sheath pipe; The far-end of operation silk is provided with clamping limb, and clamping limb in its natural state elasticity is opened, and closes when clamping limb is subject to radial constraint.
When operation silk moves axially along helical sheath pipe, can clamp and drive clip unit flexible, rotate, the protrusions match rotated on groove and clip unit fin is set, during angle when needing rotating clamp subelement to stretch out, projection and the clamping of rotation groove, helical sheath pipe and clip unit temporarily reach axial location, are conducive to ensureing stability when rotating, and improve the precision of rotation process; When the angle needed for clip unit reaches control objectives time, by moving outer sheath to the far-end of helical sheath pipe, and making it cover rotation groove, clip unit can be made to depart from axial location state with rotation groove, now push-and-pull operation silk, can drive clip unit to move.The present invention can the open mode of accurate adjustment clip unit as required, as long as and operation silk be not also separated with clip unit, the clip under open mode can be regained at any time, make it to come back in sleeve pipe, i.e. closure state.
As a modification of the present invention scheme, described rotation groove has two sections, is along the circumferential direction symmetrical arranged along helical sheath pipe far-end, and the angle of offering of every section is 0-165 °.
For ensureing the stability of operating effect, operation silk comprises cable stock, and the far-end of this cable stock is branched into two laterally, forms a pair clamping limb, and every clamping limb includes the elastic arm proximally arriving far-end and connect in turn, extensible arm and connecting portion; The side of connecting portion is semicircle, and opposite side is provided with grooving, and grooving is symmetrical arranged along semicircular axis, and the cross sectional shape of grooving is isosceles right triangle.Because connecting portion is connected with the joint near-end of clip unit, connecting portion is designed to semicircle, can reduce joint length, namely reduce the total length of the clip unit be trapped in human body; Square through hole makes the annexation between clip unit and operation silk more stable, and during both guarantees connection status, operation silk can drive clip unit synchronous axial system; The cable stock of operation silk can be formed by rustless steel skein silk system, and clamping limb then can be made up of rustless steel.
For ensureing that outer sheath energy efficient solution is except clip unit and clip control unit axial location, the inner edge of aforementioned outer sheath far distance port is provided with fillet or chamfering.
Clip control unit with the use of a clip unit, comprise clip, joint and sleeve pipe; Described sleeve side walls is provided with a pair can the fin that inside contracts of elasticity, and be provided with projection outside fin, projection may be stuck in aforementioned rotation groove; The far-end of clip in its natural state elasticity is opened, and close when being subject to radial constraint, the near-end of clip is connected with joint far-end; Joint near-end can be connected with clamping limb, can clamp and drive joint rotation, movement when clamping limb closes; Casing pipe sleeve is connected on outside joint, and both two ends places are tight fit connection, and the position corresponding with fin is that gap is arranged.Projection outside fin snaps in and rotates in groove, can the relative position of twin fixed guide-vane sleeve pipe and helical sheath pipe in the axial direction, now, firmly pull operation silk, joint can be made to move forwards, backwards along quill, realize the folding of clip, namely when clip enters in sleeve pipe, namely close, when clip departs from sleeve pipe and when being positioned at helical sheath pipe, partially open, when clip departs from sleeve pipe and helical sheath pipe simultaneously, open completely; Sleeve pipe and joint are in two ends place tight fit connection, ensure that when projection snaps in rotation groove, when operation silk ribbon moves joint rotation, the all parts of clip unit can ensure synchronous rotary, and gap is set in the position that fin is corresponding, then for the fin of pressurized leaves enough extendable rooms, ensure after clip unit is rotated in place, outer sheath compressing projection, easier can remove the axial location relation between clip unit and clip control unit.
For projection when ensureing to need can easierly slip off in rotation groove, aforementioned projection comprises the cylindrical portion of bottom, the circular top part at top.
For the stability of reinforcement clamp subelement annexation, clip comprise connected in turn by near-end to far-end U-shaped connecting portion, elastic arm, extensible arm, organize clamping part; Joint comprise connected in turn to far-end by near-end afterbody, control part, near-end fixed part, small diameter part, far-end fixed part and clip Access Division; Clip Access Division is provided with projection, the U-shaped connecting portion clamping of projection and clip; Control part is square, near-end fixed part and far-end fixed part are cylindrical, near-end fixed part and tight fit connection between far-end fixed part and sleeve pipe, can the fin that inside contracts of elasticity on the corresponding sleeve pipe in small diameter part position, and the projection on fin can in completely interior retraction sleeve pipe.Projection and the U-shaped connecting portion clamping of clip, be convenient to the assembling of joint and clip; Small diameter part be designed to fin inside contract headspace, decrease resistance when operation silk pulls joint.
For improving the stability of the rear clip unit of assembling further, near-end fixed part and far-end fixed part also respectively establish a pair block, i.e. nearly block and block far away, two pairs of blocks all coordinate with sleeve interference.The effect of nearly block provides the signal that an assembling puts in place, and namely proximal end contacts nearly block and namely assembled; The effect of block far away is after clip obtains good clamp tissue effect, withstands the proximal edge of clamp sleeve, the trend preventing clip from distally skidding off from clamp sleeve and possibility.
For strengthening the clamping effect of clip, organize occlusion place of clamping part far-end in dentation described in clip, and when clip closes, the dentation place of two occlusions place engage each other.After clip is closed, organizes intermeshing dentation place on clamping part can better clamp disease tissue, prevent clip from tissue landing.
For making extensible arm have good closure effect, elastic arm is arc-shaped, and two sections of circular arcs are tangent; Elastic arm and extensible arm, U-shaped connecting portion are all tangent in junction.This design, when ensureing that clip closes, extensible arm can close in the longitudinal direction simultaneously, and elastic arm can be smooth is drawn in sleeve pipe, and resistance when pulling is little.
Resist the ability of flexible deformation in the longitudinal direction for strengthening clip, clip cross section is V-shape Huo and stamps out a reinforcement along on the length direction of clip center line.
For ease of the assembling of whole clip unit, the wide near-end of elastic arm far-end is narrow, and the narrow near-end of extensible arm far-end is wide, and both all reach respective Breadth Maximum in joint, and U-shaped connecting portion width is less than the narrowest place of elastic arm.
Advantage of the present invention is: clip control unit can control clip and move, rotates, and it controls accurately reliable; Clip unit clamping effect desirable, and clip closed after can reopen.
accompanying drawing illustrates:
Fig. 1 is the structural representation (pushing status) of the present invention when using.
Fig. 2 is the structural representation (axial location state) of the present invention when using.
Fig. 3 is the structural representation (release state) of the present invention when using.
Fig. 4 is the structural representation (disengaged position) of the present invention when using.
Fig. 5 is the structural representation (state that clamping limb opens naturally) that the present invention operates silk.
Fig. 6 is the structural representation (state of the stressed elastic closure of clamping limb) that the present invention operates silk.
Fig. 7 is the structural representation of helical sheath pipe in clip control unit.
Fig. 8 is the structural representation of clip in clip unit.
Fig. 9 is the structural representation of clip unit center tap.
Figure 10 is the structural representation (released state) of clip unit middle sleeve.
Figure 11 is the structural representation (assembled state) of clip unit middle sleeve.
Figure 12 is the structural representation of clip unit.
detailed description of the invention:
Below in conjunction with accompanying drawing, the present invention will be further described.
As Figure 1-4, the present invention includes clip unit and clip control unit 10.
Described clip control unit 10 comprises the outer sheath 70, helical sheath pipe 60 and the operation silk 20 that are socketed in turn from outside to inside; Helical sheath pipe 60 has near-end and far-end, and its far-end is along the circumferential direction provided with and rotates groove 62a; Outer sheath 70 and operation silk 20 all can move axially along helical sheath pipe 60; The far-end of operation silk 20 is provided with clamping limb, and clamping limb is opened in elasticity in its natural state, is closure state when clamping limb is subject to radial constraint.
Described clip unit comprises clip 30, joint 40 and sleeve pipe 50; Described sleeve pipe 50 sidewall is provided with a pair can the fin 51a that inside contracts of elasticity, and be provided with projection 51b outside fin, projection 51b may be stuck in aforementioned rotation groove 62a; The far-end of clip 30 is opened in elasticity in its natural state, and be closure state when being subject to radial constraint, the near-end of clip 30 is connected with joint 40 far-end; Can clamp when clamping limb closes 40 near-end and drive joint 40 to rotate; Sleeve pipe 50 is socketed on joint 40 outer wall, and both two ends places are tight fit connection, and the position corresponding with fin 51a is that gap is arranged, when operation silk 20 drives joint 40 to rotate, and sleeve pipe 50, joint 40 synchronous rotary; Pull operation silk 20, makes clip 30 move back and forth in the internal diameter of sleeve pipe 50 by joint 40.
Use procedure is as follows:
First, the clip unit assembled pushed in helical sheath pipe 60, operation silk 20 drives clip unit to move to the far-end of helical sheath pipe 60.
Then, along with the clip unit projection 51b be distally pushed on sleeve pipe 50 snap in rotate in groove 62a time, sleeve pipe 50 and helical sheath pipe 60 axial location, now, clip unit and clip control unit 10 realize axial location, operation silk 20 needs swivel joint 40 according to operation, gets final product the angle of accurate adjustment clip; Now pulling joint 40 as operated silk 20, clip 30 being pulled in the internal diameter of sleeve pipe 50, the closed action of clip 30 can be completed; Now promoting clip 30 as operated silk 20, clip 30 being released from the internal diameter of sleeve pipe 50, clip 30 can be made to reopen; Aforementioned three modes of operation can select operation as required.
After clip 30 clamps disease tissue, the projection 51b on outside the fin 51a on sleeve pipe 50 is pressed by outer sheath 70, the axial location of decannulation 50 and helical sheath pipe 60 can be separated, aforementioned outer sheath 70 can be made up of the material such as plastics or resin, preferably on the inner edge of outer sheath 70 far distance port, be provided with fillet or chamfering, to slip over projection 51b more easily and to apply radial force to it.
Now, proximally retract helical sheath pipe 60 and outer sheath 70, come out from the internal diameter of helical sheath pipe 60 by the clamping limb of operation silk 20 far-end, clamping limb elasticity will be opened because losing radial constraint, makes clip unit depart from clip control unit 10.
As seen in figs. 5-6, operation silk 20 comprises cable stock 21, and the far-end of this cable stock 21 is branched into two laterally, forms a pair clamping limb, and wherein, every clamping limb includes the elastic arm 22 proximally arriving far-end and connect in turn, extensible arm 23 and connecting portion 24.Clamping limb presents open mode under naturally unconfined condition; The side of connecting portion 24 is semicircle, and opposite side is provided with grooving 25, and grooving 25 is symmetrical arranged along semicircular axis, and the cross sectional shape of grooving 25 is isosceles right triangle.When clamping limb is subject to radial restraining forces, the occlusal surface of the stressed closed formation copper coin shape of meeting, the foursquare through hole of occlusal surface center is docked by two groovings 25 and forms, the shape of this through hole and the form fit of previous clips unit and clamping limb junction.Connecting portion is designed to semicircle, the length of clip unit can be reduced, namely reduce the total length of the clip unit be trapped in human body; Square through hole makes the annexation between clip unit and operation silk 20 more stable, and during both guarantees connection status, operation silk 20 can drive clip unit synchronous axial system; The cable stock 21 of operation silk 20 can be formed by rustless steel skein silk system, and clamping limb then can be made up of rustless steel.
As shown in Figure 7, the far-end of helical sheath pipe 60 comprises spiral pitch of the laps 61 and distal tube 62.Spiral pitch of the laps 61 can be formed by flat stainless steel silk coiling, and distal tube 62 is processed by rustless steel, and is circumferentially with rotation groove 62a along it.
As illustrated in figs. 8-12, clip 30 comprise connected in turn by near-end to far-end U-shaped connecting portion 31, elastic arm 32, extensible arm 33, organize clamping part 34;
Described occlusion place organizing clamping part 34 far-end is dentation, and when clip 30 closes, the dentation place of two occlusions place engages each other; This organizes intermeshing dentation place on clamping part 34 can better clamp disease tissue, prevents clip 30 from tissue landing after making clip 30 closed;
Elastic arm 32 is in arc-shaped, and two sections of circular arcs are tangent, make extensible arm 33 have good closure effect;
Elastic arm 32 and extensible arm 33, U-shaped connecting portion 31 are all tangent in junction, and when ensureing that clip 30 closes with this, extensible arm 33 can close in the longitudinal direction simultaneously, and elastic arm 32 can be smooth is drawn in sleeve pipe 50, and resistance when pulling is little; Clip 30 can by metal, as rustless steel plate is stamped to form, its cross section is V-shape, this cross sectional shape strengthens the rigidity of clip, enhance the ability that it resists flexible deformation in the longitudinal direction, in addition, also along the length direction of clip center line stamping out a reinforcement, can reach equally and strengthening the effect that it resists flexible deformation's ability in the longitudinal direction;
The narrow near-end of extensible arm 33 far-end is wide, and the wide near-end of elastic arm 32 far-end is narrow; , both all reach respective maximum wide in joint, U-shaped connecting portion 31 width is less than the narrowest place of elastic arm 32; The assembling of whole clip unit is convenient in this design; U-shaped connecting portion 31 is connected with the distal projection 45 of joint 40.
Joint 40 can by resin casting, joint 40 comprise connected in turn to far-end by near-end afterbody 41, control part 42, near-end fixed part 43, small diameter part 44, far-end fixed part 48 and clip Access Division 49; Control part 42 is square, and when it closes with operation silk 20 far-end clamping limb, the square through hole that grooving 25 is formed agrees with, and this design convenient operation silk 20 drives joint 40 to rotate, and then drives clip 30 to rotate; Near-end fixed part 43 and far-end fixed part 48 are cylindrical, near-end fixed part 43 and tight fit connection between far-end fixed part 48 and sleeve pipe 50, can the fin 51a that inside contracts of elasticity on the corresponding sleeve pipe 50 in small diameter part 44 position, when fin 51a inside contracts completely, projection 51b top and sleeve pipe 50 contact internal walls, clip Access Division 49 is provided with protruding 45, protruding 45 can with U-shaped connecting portion 31 clamping of clip 30.Mainly in order to give, the fin 51a's of sleeve pipe 50 inside contract headspace for the design of small diameter part 44, also can reduce resistance when to pull joint 40 in sleeve pipe 50 internal diameter in addition.
In addition, near-end fixed part 43 and far-end fixed part 48 also respectively establish a pair block, i.e. nearly block 46 and block far away 47.The effect of nearly block 46 provides the signal that an assembling puts in place, and namely namely the nearly block 46 of sleeve pipe 50 proximal contact has been assembled; The effect of block 47 far away is after clip 30 obtains good clamp tissue effect, withstands the proximal edge of clamp sleeve, the trend preventing clip 30 from distally skidding off from clamp sleeve 50 and possibility.
Sleeve pipe 50 comprises casing main body 51 and sleeve pipe small cap 52, and casing main body 51 is by the firm resin casting with suitable elasticity; Be positioned at sleeve pipe 50 when the elastic arm 32 of clip 30 is all or part of, clip 30 is namely all closed; Because sleeve pipe small cap 52 will coordinate with clip 30, material requires it has certain rigidity, therefore can be made up of firm metals such as rustless steels; Casing main body 51 reaches molding by corresponding multidiameter with the interference fit of shoulder hole with sleeve pipe small cap 52 and is connected, being provided with in casing main body 51 periphery when being stressed for a pair can the fin 51a that inside contracts of elasticity, the periphery of fin 51a also forms two projection 51b, the thickness of fin 51a distally proximally convergent, this design is to reduce space shared when fin inside contracts.Projection 51b comprises the cylindrical section of root and the circular top part on top, when by the cylindrical section embedded rotating groove 62b of projection 51b time, can the relative position of completely locating sleeve 50 and helical sheath pipe 60 vertically.The height of projection 51b is greater than the wall thickness of helical sheath pipe 60, when by epitheca 70 push projection 51b, the cylindrical section of projection 51b can be made to be pressed into completely in the internal diameter of helical sheath pipe 60.The circular top part of further pull operation silk 20, projection 51b will slip in sheath bore along the inward flange rotating groove 62a, separate the axial location of decannulation 50 and helical sheath pipe 60.In addition, preferably can reduce the wall thickness of distal tube 62 in helical sheath pipe 60 further, the operation that the circular top part of projection 51b can be made like this to slip in helical sheath pipe 60 internal diameter is more reliable.In addition, because two sections of rotation groove 62a are incoherent, therefore clip unit can not rotate freely in the scope of 360 °, in most situation, when rotation angle range reaches 165 ° × 2=330 °, can meet operation demand.
Claims (3)
1. a clip control unit, is characterized in that: comprise the outer sheath, helical sheath pipe and the operation silk that are socketed in turn from outside to inside;
Helical sheath pipe has near-end and far-end, and its far-end is along the circumferential direction provided with the rotation groove of more than a section;
Outer sheath and operation silk all can moving axially along helical sheath pipe;
The far-end of operation silk is provided with clamping limb, and clamping limb in its natural state elasticity is opened, and closes when clamping limb is subject to radial constraint;
Operation silk comprises cable stock, the far-end of this cable stock is branched into two laterally, form a pair clamping limb, described clamping limb is not for grasping tissue, but for the joint of grip clamp, every clamping limb includes the elastic arm proximally arriving far-end and connect in turn, extensible arm and connecting portion; The side of connecting portion is semicircle, and opposite side is provided with grooving, and grooving is symmetrical arranged along semicircular axis, and the cross sectional shape of grooving is isosceles right triangle.
2. clip control unit according to claim 1, is characterized in that: described rotation groove has two sections, is along the circumferential direction symmetrical arranged along helical sheath pipe far-end, and the angle of offering of every section is 0-165 °.
3. clip control unit according to claim 1 and 2, is characterized in that: the inner edge of aforementioned outer sheath far distance port is provided with fillet or chamfering.
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CN201210018324.9A CN102525593B (en) | 2012-01-20 | 2012-01-20 | Clamp control unit and clamp unit matched with same |
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CN201210018324.9A CN102525593B (en) | 2012-01-20 | 2012-01-20 | Clamp control unit and clamp unit matched with same |
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CN102525593A CN102525593A (en) | 2012-07-04 |
CN102525593B true CN102525593B (en) | 2015-02-25 |
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Cited By (1)
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WO2018057515A1 (en) * | 2016-09-22 | 2018-03-29 | Boston Scientific Limited | Multiple opening/closing of reloadable clip |
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WO2016190190A1 (en) * | 2015-05-27 | 2016-12-01 | オリンパス株式会社 | Device for endoscope |
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CN110051398A (en) * | 2019-04-18 | 2019-07-26 | 浙江朗特医疗科技有限公司 | Dual locking tissue folder with limiting and protecting device |
CA3130453C (en) | 2019-06-19 | 2024-02-13 | Boston Scientific Scimed, Inc. | Hemostasis clip reduced length deployment mechanism |
CN110464410B (en) * | 2019-07-03 | 2024-05-10 | 安瑞医疗器械(杭州)有限公司 | Clip device for endoscope and clamping part thereof |
CN111616768B (en) * | 2020-06-16 | 2024-10-11 | 苏州市倍咏医疗科技有限公司 | Multiple clamping device and operation method |
CN111658058B (en) * | 2020-06-29 | 2022-09-13 | 安瑞医疗器械(杭州)有限公司 | Clip device for use with endoscope and clip portion thereof |
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CN202477780U (en) * | 2012-01-20 | 2012-10-10 | 东南大学 | Clamp control unit and clamp unit matched with clamp control unit in use |
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CN102065780A (en) * | 2008-06-19 | 2011-05-18 | 波士顿科学塞默迪有限公司 | Hemostatic clipping devices and methods |
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CN202477780U (en) * | 2012-01-20 | 2012-10-10 | 东南大学 | Clamp control unit and clamp unit matched with clamp control unit in use |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2018057515A1 (en) * | 2016-09-22 | 2018-03-29 | Boston Scientific Limited | Multiple opening/closing of reloadable clip |
EP3884880A1 (en) * | 2016-09-22 | 2021-09-29 | Boston Scientific Limited | Multiple opening/closing of clip |
EP3884881A1 (en) * | 2016-09-22 | 2021-09-29 | Boston Scientific Limited | Multiple opening/closing of clip |
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