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CN102430040A - Medicine for treating diabetes - Google Patents

Medicine for treating diabetes Download PDF

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Publication number
CN102430040A
CN102430040A CN2011104543840A CN201110454384A CN102430040A CN 102430040 A CN102430040 A CN 102430040A CN 2011104543840 A CN2011104543840 A CN 2011104543840A CN 201110454384 A CN201110454384 A CN 201110454384A CN 102430040 A CN102430040 A CN 102430040A
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CN
China
Prior art keywords
radix
medicine
diabetes
treating diabetes
treatment
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Pending
Application number
CN2011104543840A
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Chinese (zh)
Inventor
马士奇
王六贵
吕建英
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Shanxi Zhendong Kaiyuan Pharmaceutical Co ltd
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Shanxi Zhendong Kaiyuan Pharmaceutical Co ltd
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Priority to CN2011104543840A priority Critical patent/CN102430040A/en
Publication of CN102430040A publication Critical patent/CN102430040A/en
Pending legal-status Critical Current

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Abstract

A medicine for treating diabetes is prepared by selecting rhizoma Dioscoreae, radix astragali, rhizoma anemarrhenae, endothelium corneum Gigeriae Galli, radix Puerariae, Trichosanthis radix, Corni fructus, and radix Adenophorae, cleaning with clear water, mixing, adding conventional adjuvants, and making into pharmaceutically acceptable dosage forms such as decoction, tablet, capsule, pill, oral liquid, injection, etc. by conventional method. The medicine has the effects of invigorating primordial qi, nourishing kidney yin, strengthening spleen and stomach, promoting the production of body fluid and quenching thirst, has good treatment effect on diabetes and has no toxic or side effect.

Description

A kind of medicine of treating diabetes
Technical field
The present invention relates to a kind of medicine of treating diabetes, especially relating to a kind of is the medicine of the treatment diabetes of crude drug preparation with Chinese medicine.
Background technology
Diabetes are to act on that body causes hypoinsulinism, insulin resistant etc. and a series of metabolism disorder syndromes such as the sugar that causes, protein, fat, power and water Xie Zhi by inherited genetic factors, immunologic function disorder, infected by microbes and toxin thereof, free radical toxin, Nervous and Mental Factors or the like various virulence factors; Be a kind of common pilosity, the disease that is difficult to effect a radical cure.Be main feature with the hyperglycemia clinically, and polyuria, polydipsia, polyphagia appear, performance such as become thin, i.e. " three-many-one-little " symptom, most of patients does not have uncomfortable symptom in early days; The blood glucose long time is higher during prescription on individual diagnosis, and different degrees of complications, like retinopathy, and the foot pathological changes; Diabetes and hypertension, cerebral infarction or injury of kidney are because modern life rhythm is accelerated; The obvious rejuvenation of falling ill, its body etiology unknown, but sickness rate obviously rises.
Now treatment of diabetes is mainly realized through the Western medicine blood sugar control, like oral administration of metformin and glibenclamide, insulin injection etc., but this type of Therapeutic Method has side effect or treatment inconvenience more, is not ideal Therapeutic Method.
Summary of the invention
The purpose of this invention is to provide a kind of is the medicine of the treatment diabetes of crude drug preparation with Chinese medicine, and this medicine is the principle treatment to rise vigour, nourishing kidney-yin, strengthening the spleen and stomach, promoting the production of body fluid to quench thirst, and therapeutic effect is good, and expense is low.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Rhizoma Dioscoreae 24~36 Radix Astragali 12~18 Rhizoma Anemarrhenaes 12~18
Endothelium Corneum Gigeriae Galli 4~8 Radix Puerariaes 4~6 Radix Trichosanthis 8~12
Fructus Corni 12~18 Radix Adenophorae (Radix Glehniae) 12~18.
Get the above-mentioned raw materials medicine, add conventional adjuvant, according to common process; Process various dosage forms such as pharmaceutically acceptable decoction, tablet, capsule, pill, oral liquid, injection, wherein said common process can be a water extraction, decocte with water 2-3 time; Amount of water is a conventional amount used, merges aqueous extract, the ethanol concentrate drying; According to common process, process various dosage forms; Also can process various dosage forms by other conventional method extractions, purification, vacuum drying.
The preferred dosage form of the present invention is a powder.
The concrete method for preparing of drug powder of the present invention is: said medicine by said parts by weight mix homogeneously, is ground into 100~120 purpose medicated powder, and sterilization makes the powder product.
In the prescription of the present invention, Rhizoma Dioscoreae is strengthened the spleen and stomach, the tonifying the lung tonifying YIN; The Radix Astragali tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration; Rhizoma Anemarrhenae promoting the production of body fluid to quench thirst is nourshing Yin and drynsessmoistening prescription; The Endothelium Corneum Gigeriae Galli invigorating the stomach and promoting digestion; The Radix Puerariae promoting the production of body fluid to quench thirst; The Radix Trichosanthis clearing away heat and promoting production of body fluid; The Fructus Corni liver and kidney tonifying, convergence solid three is born; Radix Adenophorae (Radix Glehniae) nourishing the stomach to promote the production of body fluid, all medicines share, and can play the effect that rises vigour, nourishing kidney-yin, strengthening the spleen and stomach, promoting the production of body fluid to quench thirst, and are remarkable to the treatment diabetes curative effect, and cheap.
For further investigating the clinical efficacy of drug treatment of diabetic of the present invention, select 63 routine diabeticss to carry out clinical observation on the therapeutic effect.
63 routine diabeticss are divided into 2 groups, and 30 people are organized in treatment, matched group 33 people, and all case diagnosis meet the diabetes diagnosis standard of WHO formulation in 1999; Clinical symptoms ten is venous plasma blood glucose >=11.0mmol/L immediately, or empty stomach venous plasma blood glucose >=7.0mmol/L, or 2 hours venous plasma blood glucose >=11.0mmol/L of oral glucose tolerance test.
Therapeutic Method: the treatment group is taken powder agent medicine of the present invention, every day 1 time, each 10g; The matched group oral administration of metformin, once-a-day, each 0.5g.
Before and after the treatment, treatment group and each parameter of the matched group patient chamber of experimentizing inspection, see table 1:
The variation of each parameter before and after table 1 diabetic therapy
Figure 975094DEST_PATH_IMAGE001
Criterion of therapeutical effect: formulate with reference to State Administration of Traditional Chinese Medicine's " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " />.Produce effects: symptom, sign disappear, and < 7.2mmol/>L, < 8.3mmol/>L, twenty-four-hour urine sugar is < 10.0g quantitatively for 2 hours after the meal blood glucose for fasting glucose.Effectively: treatment back symptom is obviously improved, and < 8.3mmol/>L, < 10mmolL, twenty-four-hour urine sugar is < 25.0g quantitatively for 2 hours after the meal blood glucose for fasting glucose.Invalid: treatment back symptom does not have obvious improvement, and blood glucose, glucose in urine descend and do not reach above-mentioned standard.
Two groups of case treatment back curative effect comparative results are seen table 2.
Table 2 liang group case treatment back curative effect relatively.
Group The example number Produce effects n (%) Effective n (%) Invalid n (%) Total effective rate n (%)
Matched group 33 11(33.3) 14(42.5) ?8(24.2) 25(75.8)
The treatment group 30 20(66.7) 6(20) 4(13.3) 26(86.7)
The specific embodiment
Embodiment 1
Get Rhizoma Dioscoreae 240g, Radix Astragali 120g, Rhizoma Anemarrhenae 120g, Endothelium Corneum Gigeriae Galli 40g, Radix Puerariae 40g, Radix Trichosanthis 80g, Fructus Corni 120g, Radix Adenophorae (Radix Glehniae) 180g mix homogeneously selected, that clear water is cleaned, be ground into 100~120 medicated powder, sterilization makes the powder product.
Embodiment 2
Get Rhizoma Dioscoreae 360g, Radix Astragali 180g, Rhizoma Anemarrhenae 180g, Endothelium Corneum Gigeriae Galli 80g, Radix Puerariae 60g, Radix Trichosanthis 120g, Fructus Corni 180g, Radix Adenophorae (Radix Glehniae) 180g mix homogeneously selected, that clear water is cleaned; Be ground into 100~120 medicated powder; Sterilization in incapsulating by conventional method, is processed capsule.

Claims (2)

1. medicine of treating diabetes is that crude drug prepares by the Chinese medicine of following portions by weight:
Rhizoma Dioscoreae 24~36 Radix Astragali 12~18 Rhizoma Anemarrhenaes 12~18
Endothelium Corneum Gigeriae Galli 4~8 Radix Puerariaes 4~6 Radix Trichosanthis 8~12
Fructus Corni 12~18 Radix Adenophorae (Radix Glehniae) 12~18.
2. the medicine of treatment diabetes according to claim 1; It is characterized in that getting the above-mentioned raw materials medicine; Add conventional adjuvant,, process various dosage forms such as pharmaceutically acceptable decoction, tablet, capsule, pill, oral liquid, injection according to common process.
CN2011104543840A 2011-12-30 2011-12-30 Medicine for treating diabetes Pending CN102430040A (en)

Priority Applications (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108042684A (en) * 2018-01-25 2018-05-18 王茂全 A kind of Chinese medicine composition for treating diabetes B and preparation method thereof
CN111195326A (en) * 2018-11-19 2020-05-26 安顺玉龙医院 Preparation method of blood sugar-reducing and thirst-quenching powder

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101125173A (en) * 2007-09-07 2008-02-20 王慧林 Traditional Chinese medicine 'guiyuantangkang' for treating diabetes and its complication
CN101138369A (en) * 2006-09-06 2008-03-12 蔡如桂 Thirst-eliminating tea
CN101491629A (en) * 2008-01-21 2009-07-29 北京晨钟荣福科技有限公司 Medicine composition for treating diabetes and preparation method thereof
CN101947284A (en) * 2010-09-19 2011-01-19 蔡伦 Traditional Chinese medicinal composition for treating diabetes and preparation method thereof
CN102145120A (en) * 2011-03-31 2011-08-10 山东大学 A kind of traditional Chinese medicine composition suitable for preparing and treating type II diabetes

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101138369A (en) * 2006-09-06 2008-03-12 蔡如桂 Thirst-eliminating tea
CN101125173A (en) * 2007-09-07 2008-02-20 王慧林 Traditional Chinese medicine 'guiyuantangkang' for treating diabetes and its complication
CN101491629A (en) * 2008-01-21 2009-07-29 北京晨钟荣福科技有限公司 Medicine composition for treating diabetes and preparation method thereof
CN101947284A (en) * 2010-09-19 2011-01-19 蔡伦 Traditional Chinese medicinal composition for treating diabetes and preparation method thereof
CN102145120A (en) * 2011-03-31 2011-08-10 山东大学 A kind of traditional Chinese medicine composition suitable for preparing and treating type II diabetes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
《四川中医》 19830315 樊学成等 加味玉液汤治疗消渴证 , 第03期 *
张锡纯(清) 原著: "《医学衷中参西录》", 31 January 2007, article "【玉液汤】" *
樊学成等: "加味玉液汤治疗消渴证", 《四川中医》, no. 03, 15 March 1983 (1983-03-15) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108042684A (en) * 2018-01-25 2018-05-18 王茂全 A kind of Chinese medicine composition for treating diabetes B and preparation method thereof
CN111195326A (en) * 2018-11-19 2020-05-26 安顺玉龙医院 Preparation method of blood sugar-reducing and thirst-quenching powder

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Application publication date: 20120502