CN102247656A - Novel light-emitting diode (LED) phototherapy health-care device - Google Patents
Novel light-emitting diode (LED) phototherapy health-care device Download PDFInfo
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- CN102247656A CN102247656A CN2011100862141A CN201110086214A CN102247656A CN 102247656 A CN102247656 A CN 102247656A CN 2011100862141 A CN2011100862141 A CN 2011100862141A CN 201110086214 A CN201110086214 A CN 201110086214A CN 102247656 A CN102247656 A CN 102247656A
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Abstract
The invention relates to a novel light-emitting diode (LED) phototherapy health-care device. The novel LED phototherapy health-care device comprises a shell, a central control module, a keystroke module and a display module, wherein the central control module is installed inside the shell and is connected with the keystroke module and the display module, both of which are embedded on the shell; the central control module is connected with a controlled terminal of a power supply control module; an input terminal of the power supply control module is connected with mains supply; an output end of the power supply control module is connected with multiple sockets embedded on the shell; and a plug inserted in each socket is connected with an LED module embedded on a substrate through cables. In the novel LED phototherapy health-care device provided by the invention, a host is connected with multiple LED modules on the substrate, so that the single treatment function of the conventional equipment is solved; and the novel LED phototherapy health-care device can be used for the treatment of multiple diseases and different treatment stages of one disease, has good integral treatment effect, and is multifunctional medical treatment and prevention health-care equipment used clinically in hospitals and households in communities.
Description
Technical field
The invention belongs to phototherapy health care facility field, especially a kind of New LED phototherapy protection device.
Background technology
Scientific research proves, certain frequency, the LED light of intensity to human exposure after, can produce positive biological medical effect, promote the microcirculation of human body, improve immune vigor, and can strengthen the oxygen carrying capacity of blood rbc, so people have invented various phototherapy apparatus, its general structure is: comprise housing, central control module, light emission module, key-press module and display module, central control module be installed in the housing and with housing on the key-press module of institute's setting-in be connected with display module, central control module connects the controlled terminal of power supply control module, the input of power supply control module connects civil power, the outfan of power supply control module connects an end of light emission module, and the other end of light emission module connects the outer phototherapy probe that is provided with of housing by optical fiber or cable.
In the said structure, light emission module is arranged in the housing, and its light frequency of launching is fixed, and the user must buy more therapeutic equipment and satisfy different needs.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, a kind of New LED phototherapy protection device simple in structure, with low cost is provided.
The technical scheme that the present invention takes is:
A kind of New LED phototherapy protection device, comprise housing, central control module, key-press module and display module, central control module be installed in the housing and with housing on the key-press module of institute's setting-in be connected with display module, central control module connects the controlled terminal of power supply control module, the input of power supply control module connects civil power, it is characterized in that: the outfan of described power supply control module connects a plurality of sockets that are inlaid on the housing, and the plug of plug-in mounting all connects the LED module of institute's setting-in on the substrate in each socket by cable.
And, described LED module comprises a plurality of LED lamp pearls and drive circuit module, drive circuit module is inlaid in the substrate, a plurality of LED lamp pearls are installed in the surface of drive circuit module with the matrix arrangement mode, and upper end and substrate surface outside or each LED lamp pearl that substrate is stretched out in the upper end of each LED lamp pearl are in same horizontal plane.
And the wavelength of light that described LED lamp pearl sends is 800～900nm.
And the wavelength of light that described LED lamp pearl sends is 610～650nm.
And the wavelength of light that described LED lamp pearl sends is 420～470nm.
And described substrate is that elastomeric material is made.
Advantage of the present invention and good effect are:
1. be provided with a plurality of substrates in this therapy equipment, the LED module all is installed on each substrate, each LED module adopts the LED lamp pearl of different wave length, has realized that an equipment possesses different treatment functions.
2. in this therapy equipment, substrate is made by elastomeric material, and drive circuit module is also made by flexible PCB, but the two free bend can make the LED module be fitted in the different parts of human body, and is user-friendly.
3. in this therapy equipment, substrate connects socket on the housing by plug, simple operation, and when not using, the user can will deposit in the whole income packing of substrate easily, not the side of occupation of land.
4. in this therapy equipment; wavelength is that the LED light of 610～650nm and 800～900nm can stimulate the human vas endotheliocyte to produce nitric oxide; nitric oxide can play effects such as blood vessel dilating, antiplatelet aggregation, the transmission of participation nerve signal and mediation immunoreation; nitric oxide has protective effect to many organ cells simultaneously; the LED light of 420～470nm has played antiinflammatory and germ-resistant effect; as seen the LED module of various wavelength is used in combination; can effectively improve therapeutic effect, help the rehabilitation of human body.
5. among the present invention, main frame connects the LED module on a plurality of substrates, solved the problem of legacy equipment treatment function singleness, the different treatment stages that can be used for multiple treatment of diseases and same disease, whole therapeutic effect is good, is multi-functional medical treatment, prevention and health care equipment that a kind of hospital clinical and community family use.
Description of drawings
Fig. 1 is a structural representation of the present invention;
Fig. 2 is a circuit block diagram;
Fig. 3 is the structural representation of substrate, drive circuit module and LED lamp pearl.
The specific embodiment
Below in conjunction with embodiment, the present invention is further described, and following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
A kind of New LED phototherapy protection device, shown in Fig. 1～3, comprise housing 10, central control module, key-press module 3 and display module 9, central control module be installed in the housing and with housing on the key-press module of institute's setting-in be connected with display module, central control module connects the controlled terminal of power supply control module, the input of power supply control module connects civil power, innovation of the present invention is: the outfan of power supply control module connects a plurality of sockets 8 that are inlaid on the housing, and the plug 6 of plug-in mounting all connects the LED module 2 of institute's setting-in on the substrate 1 in each socket by cable 5.
In the present embodiment, plug uses the bigger audio jack of diameter, can bear big electric current like this, and substrate adopts elastomeric material to make.The LED module comprises a plurality of LED lamp pearls 2 and drive circuit module 12, drive circuit module is inlaid in the substrate, a plurality of LED lamp pearls are installed in the surface of drive circuit module with the matrix arrangement mode, the outside that substrate is stretched out in the upper end of each LED lamp pearl, upper end of each LED lamp pearl and substrate surface are in same horizontal plane and also are fine certainly.Drive circuit module is a flexible PCB, but substrate and drive circuit module free bend, and pliability is good, can well be fitted in the surface of human body.
In order to realize different therapeutic purposes, the wavelength of light that LED lamp pearl on several substrates sends can be selected in 800～900nm scope, and the wavelength of light that the LED lamp pearl on several substrates sends can be selected in 610～650nm scope, and the wavelength of light that the LED lamp pearl on several substrates sends can be selected in 420～470nm scope, and optimal wavelength is at 890nm, 630 and the light of 465nm.
Wavelength is that the LED light of 630nm and 890nm can stimulate the human vas endotheliocyte to produce nitric oxide; nitric oxide production biological effect comprises that mainly blood vessel dilating, antiplatelet aggregation, participation nerve signal transmit, mediate immunoreation etc.; nitric oxide has protective effect to many organ cells simultaneously, and the LED light of 465nm mainly contains antiinflammatory, sterilization effects.
Among the present invention, main frame connects the LED module on a plurality of substrates, solved the problem of legacy equipment treatment function singleness, the different treatment stages that can be used for multiple treatment of diseases and same disease, whole therapeutic effect is good, is multi-functional medical treatment, prevention and health care equipment that a kind of hospital clinical and community family use.
Application Example 1:
630NM shines experiment
One, experimentation
1. endotheliocyte is cultivated: with body weight is the healthy white mouse of (180 scholar 20) g, and male and female are not limit, and get ventral aorta, with organize that Explant culture carries out endotheliocyte former be commissioned to train foster.
2. experiment grouping: take out the culture bottle that an endotheliocyte has grown up to sheet, digest the back and add the M199 culture medium 10ml that contains 10% hyclone, be diluted to 1X10 behind the counting
4The concentration of individual/100 μ l.Be inoculated into respectively in 3 48 well culture plates, every plate adds 24 holes, every hole 100 μ l, and per 6 holes are one group, totally 4 groups, wherein 1 group is matched group, adopts the simulated light photograph, remainingly is the illumination group.Put after the inoculation in people's incubator, treat that cell grows up to monolayer after, with the irradiation of the red laser of 3mw, be respectively irradiation 10min, 20min, 30min group, irradiation distance is 2cm, spot diameter is 1cm, shaven head is close to the culture plate lid during irradiation.
3. the collection of culture supernatant: after every group of irradiation finishes, add M199 culture medium 1ml, continue to cultivate.Get supernatant 0.9ml respectively at irradiation end back 15min, 30min, 1h, 3h, 6h, one 80 ℃ of preservations detect in batch, and (trypan blue dyeing) is counted to every hole living cells simultaneously.
4. the collection and treatment of SABC cell: by the cell that above-mentioned steps is handled, through digesting after, collect each cellular control unit, fix, embedding, the conventional section, use for SABC.
5.NO mensuration: NO detect to adopt enzyme process, and testing result is converted into per 10
5The amount of the secreted NO of individual cell.
Two, statistical analysis
Data are carried out variance analysis, adopt 11.0 editions statistical analysis softwares of SPSS to carry out statistical analysis.
Three, result
The influence of the internal skin cell secretion NO of HONGGUANG irradiation back 15min, each illumination group endotheliocyte secretion level is than matched group obviously raise (P＜0.01); Irradiation back 1h, the equal peaking of level of each experimental group secretion NO, wherein obvious with irradiation 30min group, descend gradually later on, 6h each experimental group secretion NO level in irradiation back sees Table 1 than matched group difference not statistically significant (P＞0.05).
Table 1: the influence of the internal skin cell secretion NO of different irradiation times (μ mol/L)
Compare with matched group in the irradiation back, NO improves 2.67 times.
Application Example 2:
890NM shines experiment
One, unit
The Second Hospital of Jilin Universtiy's department of endocrinology.
Object: 41 routine diabetes peripheral nerve pathological changes patients.. 41 routine patient's random digit methods are divided into matched group 15 example and 26 examples are organized in treatment, matched group man 7 examples, women 8 examples, mean age (63.62 ± 6.85) year, average course of disease (8.39 ± 3.50) year; Male 18 examples are organized in treatment, women 8 examples, year mean age (63.62 ± 6.16), average course of disease (7.73 ± 2.04) year.
Two, method
Therapeutic Method: matched group: accept Ginaton (gingko leaf preparation) intravenous drip treatment, 70mg/ time, 1 time/d, continuous 14d.Treatment group: accept identical Ginaton treatment with matched group (same dose, the course of treatment, injection system), carry out 890nm HONGGUANG intravascular brachytherapy simultaneously.The treatment pad of health-care appliance is positioned over diseased region skin (such as cacesthenic hands or foots such as numbness, pain), 4 treatment pads of most of placement, the Laser emission debugging power is at 420～480mW, and treatment time is 45min/ time, carry out altogether 1 course of treatment (every day one twice, totally 10 times).
Observation index and detection method: extract selected patients serum ,-20 ℃ of cold preservation nitric oxide to be measured and number of free radical.Two groups all in the end receive treatment for 1 time after, serum ,-20 ℃ of cold preservations are got in blood drawing.Treat to survey nitric oxide and number of free radical after specimen collection finishes.Determination of nitric oxide is with nitrate reductase method (test kit that bio-engineering research provides is built up in Nanjing), oxidation resistance is measured with anti-super oxygen and is produced ultra-oxygen anion free radical method of testing (test kit that bio-engineering research provides is built up in Nanjing), method is undertaken by test kit explanation that (illustrate: the change in value of free radical resisting ability can reflect the variation of number of free radical indirectly, be that the free radical resisting ability is big more, number of free radical is then more little, is inverse relation.For ease of understanding, according to circumstances the variation of free radical resisting ability is directly claimed the minimizing or the increase of number of free radical in the literary composition).
Three, result
The variation of serum levels of nitric oxide and number of free radical sees Table 2 before and after two groups of patient treatments.
Table 2: the variation of nitric oxide and number of free radical
Treat between preceding two groups of groups and compare, serum levels of nitric oxide and free radical level do not have significant difference (P＜0.05).
Compare between the two groups of groups in treatment back: the serum levels of nitric oxide of treatment group and free radical level are apparently higher than matched group, and difference has statistical significance (P＜0.05).
Compare with matched group in the irradiation back, NO improves 2.89 times, and the free radical resisting ability improves 1.77 times.
In sum, in two application examples, behind 630NM and the 890NM rayed human body, can effectively improve the content of NO in the blood.NO is an important cells messenger molecule of regulating systema cariovasculare functional, functions such as its antiplatelet, adjusting antiotasis are in cardiovascular disease, play an important role as in the developing of coronary heart disease, heart failure, atherosclerosis, thrombosis etc., by endotheliocyte and microenvironment be used for realizing protective effect to blood vessel; Pulmonary disease such as pulmonary hypertension, chronic cardiopulmonary disease, bronchial asthma, acute plateau pneumochysis also there is therapeutical effect; To blood sugar regulation, to improve diabetic nephropathy, diabetic peripheral neuropathy, diabetic cardiomyopathy etc. useful, researchs and proposes because of many, the active change of NO growing amount and nitric oxide synthetase is one of important mechanisms that causes chronic complicating diseases of diabetes; Promote repair in trauma, NO is one of key factor of wound healing, can promote the chemotactic of inflammatory cell during low concentration, and the irritation cell hypertrophy strengthens synthesizing and deposition of collagen, promotes new vessels to generate; Can reduce ischemical reperfusion injury and antitumor action is arranged.
Claims (6)
1. New LED phototherapy protection device, comprise housing, central control module, key-press module and display module, central control module be installed in the housing and with housing on the key-press module of institute's setting-in be connected with display module, central control module connects the controlled terminal of power supply control module, the input of power supply control module connects civil power, it is characterized in that: the outfan of described power supply control module connects a plurality of sockets that are inlaid on the housing, and the plug of plug-in mounting all connects the LED module of institute's setting-in on the substrate in each socket by cable.
2. New LED phototherapy protection device according to claim 1, it is characterized in that: described LED module comprises a plurality of LED lamp pearls and drive circuit module, drive circuit module is inlaid in the substrate, a plurality of LED lamp pearls are installed in the surface of drive circuit module with the matrix arrangement mode, and it is identical with the substrate surface height that the upper end outside or each LED lamp pearl of substrate is stretched out in the upper end of each LED lamp pearl.
3. New LED phototherapy protection device according to claim 1 is characterized in that: the wavelength of light that described LED lamp pearl sends is 800～900nm.
4. New LED phototherapy protection device according to claim 1 is characterized in that: the wavelength of light that described LED lamp pearl sends is 610～650nm.
5. New LED phototherapy protection device according to claim 1 is characterized in that: the wavelength of light that described LED lamp pearl sends is 420～470nm.
6. according to any described New LED phototherapy protection device in the claim 1～5, it is characterized in that: described substrate is that elastomeric material is made.
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104784829A (en) * | 2015-04-30 | 2015-07-22 | 重庆邮电大学 | Intelligent multispectral physiotherapy device with electrocardiographic feedback control function |
| CN104922801A (en) * | 2014-03-18 | 2015-09-23 | 北京创盈光电科技有限公司 | Irradiation treatment LED instrument for neonatal jaundice |
| CN108136196A (en) * | 2015-07-28 | 2018-06-08 | 光子医疗设备公司 | For the system and method adjusted to nitric oxide production phototherapy |
| US10688315B2 (en) | 2015-07-28 | 2020-06-23 | Know Bio, Llc | Phototherapy devices for treatment of dermatological disorders of the scalp |
| US11147984B2 (en) | 2020-03-19 | 2021-10-19 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11654294B2 (en) | 2021-03-15 | 2023-05-23 | Know Bio, Llc | Intranasal illumination devices |
| US11975215B2 (en) | 2020-05-26 | 2024-05-07 | Know Bio, Llc | Devices and related methods for phototherapeutic treatment of skin |
| US11986666B2 (en) | 2020-03-19 | 2024-05-21 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US12011611B2 (en) | 2020-03-19 | 2024-06-18 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US12029914B2 (en) | 2015-07-28 | 2024-07-09 | Know Bio, Llc | Phototherapeutic light for treatment of pathogens |
| US12115384B2 (en) | 2021-03-15 | 2024-10-15 | Know Bio, Llc | Devices and methods for illuminating tissue to induce biological effects |
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| CN104922801A (en) * | 2014-03-18 | 2015-09-23 | 北京创盈光电科技有限公司 | Irradiation treatment LED instrument for neonatal jaundice |
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| US11524173B2 (en) | 2015-07-28 | 2022-12-13 | Know Bio, Llc | Systems and methods for phototherapeutic modulation of nitric oxide |
| US10569097B2 (en) | 2015-07-28 | 2020-02-25 | Photonmd, Inc. | Systems and methods for phototherapeutic modulation of nitric oxide |
| US10688315B2 (en) | 2015-07-28 | 2020-06-23 | Know Bio, Llc | Phototherapy devices for treatment of dermatological disorders of the scalp |
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| US12109429B2 (en) | 2015-07-28 | 2024-10-08 | Know Bio, Llc | Phototherapeutic light for treatment of pathogens |
| US11400309B2 (en) | 2015-07-28 | 2022-08-02 | Know Bio, Llc | Phototherapy devices for treatment of dermatological disorders of the scalp |
| CN108136196A (en) * | 2015-07-28 | 2018-06-08 | 光子医疗设备公司 | For the system and method adjusted to nitric oxide production phototherapy |
| US11617895B2 (en) | 2015-07-28 | 2023-04-04 | Know Bio, Llc | Systems and methods for phototherapeutic modulation of nitric oxide |
| US12029914B2 (en) | 2015-07-28 | 2024-07-09 | Know Bio, Llc | Phototherapeutic light for treatment of pathogens |
| US11986666B2 (en) | 2020-03-19 | 2024-05-21 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11752359B2 (en) | 2020-03-19 | 2023-09-12 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11684798B2 (en) | 2020-03-19 | 2023-06-27 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US12011611B2 (en) | 2020-03-19 | 2024-06-18 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11147984B2 (en) | 2020-03-19 | 2021-10-19 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11975215B2 (en) | 2020-05-26 | 2024-05-07 | Know Bio, Llc | Devices and related methods for phototherapeutic treatment of skin |
| US11654294B2 (en) | 2021-03-15 | 2023-05-23 | Know Bio, Llc | Intranasal illumination devices |
| US12115384B2 (en) | 2021-03-15 | 2024-10-15 | Know Bio, Llc | Devices and methods for illuminating tissue to induce biological effects |
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Application publication date: 20111123 |