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CN102225125B - Externally applied traditional Chinese medicine composite for treating joint pain caused by rheumatoid arthritis and preparation method thereof - Google Patents

Externally applied traditional Chinese medicine composite for treating joint pain caused by rheumatoid arthritis and preparation method thereof Download PDF

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CN102225125B
CN102225125B CN 201110166597 CN201110166597A CN102225125B CN 102225125 B CN102225125 B CN 102225125B CN 201110166597 CN201110166597 CN 201110166597 CN 201110166597 A CN201110166597 A CN 201110166597A CN 102225125 B CN102225125 B CN 102225125B
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medicine
medicinal liquid
radix aconiti
rheumatoid arthritis
ethanol
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马玉伟
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Abstract

The invention provides an externally applied traditional Chinese medicine composite, named liquor for activating blood circulation and rehabilitating bones, for treating the joint pain caused by rheumatoid arthritis and a preparation method thereof, wherein the medicine comprises the following components: frankincense, myrrh, processed radix aconiti, prepared radix aconiti agrestis, Japanese creeper, Chinese photinia leaf, red psychotria leaf, Chinese silkvine rootbark, caulis spatholobi, red flower, angelica dahurica, borneol powder and 60% alcohol. The medicine composite provided by the invention can safely and effectively treat the joint pain caused by rheumatoid arthritis and has the advantages of fast effect acting, short treatment course and high cure rate.

Description

A kind of external medicine composition for the treatment of the osteoarthrosis pain that rheumatoid causes and preparation method thereof
Technical field
Active bone health liquid) and preparation method thereof the present invention relates to a kind of external medicine composition for the treatment of the osteoarthrosis pain that rheumatoid causes (has another name called:.
Background technology
The osteoarthrosis pain that rheumatism, rheumatoid disease cause, cervical spondylosis, arthritis, gout etc., the traditional Chinese medical science is referred to as arthromyodynia, refers to human body flesh table, and meridians cause limbs because of the damp that is affected by the cold; catch cold; contract a cold, pain is located in joints etc., miserable numbness is weighing, and moving obstacle is the disease of cardinal symptom, can't take care of oneself, serious the healthy of people that endangering.Its main pathogenesis is; QI and blood numbness resistance is obstructed, muscle arteries and veins joint lose in moisten support due to.Have clinically characteristics gradual and that repeatedly show effect.And traditional Therapeutic Method; As massaging, massage, acupuncture-moxibustion, physical therapys etc. can be alleviated for the moment pain.Doctor trained in Western medicine thinks that primary disease is the inflammation disease of the acute or chronic whole body connective tissue of a kind of outbreak repeatedly of causing after upper respiratory tract infection due to Hemolytic streptococcus, the most remarkable with heart and joint involvement, general adopt oral western medicine as, non-steroidal anti-inflammatory drugs and glucocorticoid and act on slowly antirheumatic Antipyretic is arranged, the gentle effect of separating the prevention arthritis of antiinflammatory, easily recurrence after drug withdrawal, and side effect is large, should not take for a long time.
In present existing technology, the western medical treatment primary disease is often with methods such as anti-inflammatory analgetic, hormone, sealing, ultraviolet radiation, traction, operations.Its shortcoming is to cure the symptoms, not the disease, and treatment time is long, weak curative effect, and expense is large, and surgical risk is high.The traditional Chinese medical science adopts Chinese medicine for oral administration, with methods such as relaxing muscles and tendons and activating QI and blood in the collateral, blood circulation promoting and blood stasis dispelling, and DeGrain, perhaps just clothes are effectively subsequently without effect, and curative effect is not lasting, and relapse rate is high.And Chinese medicine for oral administration is inconvenient, and some Chinese medicine has stimulation to stomach, produces bad side effect.
Summary of the invention
The objective of the invention is to overcome the prior art deficiency, the purpose of this invention is to provide a kind of external medicine composition (active bone health liquid) for the treatment of the osteoarthrosis pain that rheumatoid causes and preparation method thereof and provide, and instant effect, short treating period, Chinese medicine that cure rate is high.
For realizing purpose of the present invention, existing according to following technical scheme.This medicine is made by following raw material: be comprised of Olibanum, Myrrha, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, parthenocissus, Folium Photiniae (Folium Photiniae serrulatae), Folium et Cacumen Psychotriae Rubrae, Cortex Periplocae, Caulis Spatholobi, Flos Carthami, the Radix Angelicae Dahuricae, Borneolum Syntheticum powder, 60% ethanol (volume ratio).
Preferably component calculates by weight: pharmaceutical composition is comprised of Olibanum 10g, Myrrha 13g, Radix Aconiti Preparata 22g, Radix Aconiti Kusnezoffii Preparata 6g, parthenocissus 10g, Folium Photiniae (Folium Photiniae serrulatae) 13g, Folium et Cacumen Psychotriae Rubrae 7g, Cortex Periplocae 11g, Caulis Spatholobi 5g, Flos Carthami 7g, Radix Angelicae Dahuricae 3g, Borneolum Syntheticum powder 10g, 60% ethanol (volume ratio) 1000ml.
Perhaps: pharmaceutical composition is comprised of Olibanum 8g, Myrrha 10g, Radix Aconiti Preparata 20g, Radix Aconiti Kusnezoffii Preparata 8g, parthenocissus 7g, Folium Photiniae (Folium Photiniae serrulatae) 10g, Folium et Cacumen Psychotriae Rubrae 9g, Cortex Periplocae 12g, Caulis Spatholobi 6g, Flos Carthami 6g, Radix Angelicae Dahuricae 2g, Borneolum Syntheticum powder 12g, 60% ethanol (volume ratio) 1000ml.
The preparation technology of compositions of the present invention is:
1) decoct: above-mentioned all medicines that will not comprise Borneolum Syntheticum powder and 60% ethanol are put into marmite, add the decoction of hydrology fire by 1: 8 of medicine gross mass, boil rear 60 minutes, medicinal liquid is leached, by the medicine gross mass 1: 2 adds the decoction of hydrology fire again, boils rear 30 minutes, and medicinal liquid is leached;
2) above-mentioned medicinal liquid is reentered into decocts in clean earth pot to thick, moisture is removed in oven dry, makes the dry product medicine;
3) the dry product medicine is placed in container and adds 60% ethanol 1000ml, add Borneolum Syntheticum powder 10-12g, and mix homogeneously, bottling after sterilization.
Method of application: the used time is applied to medicinal liquid and spreads on the arthritis sore spot on gauze.Change dressings night every day 1 time.
Embodiment
Embodiment 1,
Pharmaceutical composition is comprised of Olibanum 10g, Myrrha 13g, Radix Aconiti Preparata 22g, Radix Aconiti Kusnezoffii Preparata 6g, parthenocissus 10g, Folium Photiniae (Folium Photiniae serrulatae) 13g, Folium et Cacumen Psychotriae Rubrae 7g, Cortex Periplocae 11g, Caulis Spatholobi 5g, Flos Carthami 7g, Radix Angelicae Dahuricae 3g, Borneolum Syntheticum powder 10g, 60% ethanol (volume ratio) 1000ml.
The preparation technology of described compositions is:
1) decoct: above-mentioned all medicines that will not comprise Borneolum Syntheticum powder and 60% ethanol are put into marmite, add the decoction of hydrology fire by 1: 8 of medicine gross mass, boil rear 60 minutes, medicinal liquid is leached, by the medicine gross mass 1: 2 adds the decoction of hydrology fire again, boils rear 30 minutes, and medicinal liquid is leached;
2) above-mentioned medicinal liquid is reentered into decocts in clean earth pot to thick, moisture is removed in oven dry, makes the dry product medicine;
3) the dry product medicine is placed in container and adds 60% ethanol 1000ml, add Borneolum Syntheticum powder 10g, and mix homogeneously, bottling after sterilization.Method of application: the used time is applied to medicinal liquid 20ml and spreads on the arthritis sore spot on gauze.Change dressings night every day 1 time.Every 7 days is a course for the treatment of, can cure after 4-5 the course for the treatment of.
Embodiment 2,
Pharmaceutical composition is comprised of Olibanum 8g, Myrrha 10g, Radix Aconiti Preparata 20g, Radix Aconiti Kusnezoffii Preparata 8g, parthenocissus 7g, Folium Photiniae (Folium Photiniae serrulatae) 10g, Folium et Cacumen Psychotriae Rubrae 9g, Cortex Periplocae 12g, Caulis Spatholobi 6g, Flos Carthami 6g, Radix Angelicae Dahuricae 2g, Borneolum Syntheticum powder 12g, 60% ethanol (volume ratio) 1000ml.
The preparation technology of compositions of the present invention is:
1) decoct: above-mentioned all medicines that will not comprise Borneolum Syntheticum powder and 60% ethanol are put into marmite, add the decoction of hydrology fire by 1: 8 of medicine gross mass, boil rear 60 minutes, medicinal liquid is leached, by the medicine gross mass 1: 2 adds the decoction of hydrology fire again, boils rear 30 minutes, and medicinal liquid is leached;
2) above-mentioned medicinal liquid is reentered into decocts in clean earth pot to thick, moisture is removed in oven dry, makes the dry product medicine;
3) the dry product medicine is placed in container and adds 60% ethanol 1000ml, add Borneolum Syntheticum powder 12g, and mix homogeneously, bottling after sterilization.Method of application: the used time is applied to the 20ml medicinal liquid and spreads on the arthritis sore spot on gauze.Change dressings night every day 1 time.Every 7 days is a course for the treatment of, can cure after 4-5 the course for the treatment of.
The clinical treatment treatment:
1, data is selected arthritis, arthralgia patient's 60 examples that the court's outpatient clinic rheumatism, rheumatoid cause, male 29 examples, female's 31 examples; 45~70 years old age.Not with antibiotic or cancer therapy drug, eliminating sickens for consciousness or psychological problem person selected case, and severe cardiac, brain, liver, kidney, blood, endocrine system disease is arranged and medicine is had allergies and allergic constitution person in 6 months.Be divided at random treatment and matched group, every group of 30 examples, 2 groups of ordinary circumstances have comparability.
2, Therapeutic Method treatment group: the 20ml medicinal liquid is applied to spreads on the arthritis sore spot on gauze, change dressings night every day 1 time.Every 7 days is a course for the treatment of.Matched group: 2) Radix Tripterygii Wilfordii tablet, treatment rheumatoid pain conventional medicine, Huangshi 999 Pharmaceutical Co., Ltd. produces, and each 2, every day 3 times, clothes after the meal.
Statistical procedures uses SPSS 10.0 softwares to carry out statistical analysis, and data represent with x ± s, relatively adopt variance analysis between group, and enumeration data adopts X 2Check, P<0.05 is for there being significant difference.
3. therapeutic effect compares (table 1)
Figure BSA00000521349900031
Conclusion: treatment group and matched group all can bring certain therapeutic effect, but after treating for 3 weeks, the treatment group matched group that is better than evident in efficacy has significant difference P<0.05.
Model case:
Every 7 days is a course for the treatment of, generally, can cure after 3-4 the course for the treatment of.Concrete case is as follows:
Case 1: Wu Yuanxia, the female, 68 years old, Linyi City city water conservancy bureau retired person suffered from rheumatoid arthritis for many years, and arthralgia is wiped and is cured after 4 courses for the treatment of with medicinal liquid of the present invention unbearably, follows up a case by regular visits to and has no recurrence in 1 year.
Case 2: Li Xuenian, the man, 71 years old, people from Fei County, Shandong suffered from rheumatoid arthritis for many years, and outstanding with lumbar vertebra, wiped with medicinal liquid of the present invention and namely cured after 4 courses for the treatment of, followed up a case by regular visits to and had no recurrence half a year.
Case 3: Xuan Lihua, the man, 58 years old, the Yishui, Shandong people suffered from projection of cervical vertebra for many years, and pain is obvious, wipes with medicinal liquid of the present invention and namely cures after 3 courses for the treatment of, follows up a case by regular visits to and has no recurrence half a year.
Case 4: Wang Jianguo, the man, 66 years old, the retirement veteran cadre of Luozhuang District regional planning agency suffered from prolapse of lumbar intervertebral disc more than 10 year, obstinate, wipe with medicinal liquid of the present invention after 4 courses for the treatment of pain disappear, follow up a case by regular visits to and had no recurrence in 1 year.

Claims (1)

1. external medicine composition for the treatment of the osteoarthrosis pain that rheumatoid causes, it is characterized in that: described compositions is made by Olibanum 10g, Myrrha 13g, Radix Aconiti Preparata 22g, Radix Aconiti Kusnezoffii Preparata 6g, parthenocissus 10g, Folium Photiniae (Folium Photiniae serrulatae) 13g, Folium et Cacumen Psychotriae Rubrae 7g, Cortex Periplocae 11g, Caulis Spatholobi 5g, Flos Carthami 7g, Radix Angelicae Dahuricae 3g, Borneolum Syntheticum powder 10g, 60% ethanol 1000ml
The preparation technology of described compositions is:
1) decoct: above-mentioned all medicines that will not comprise Borneolum Syntheticum powder and 60% ethanol are put into marmite, add the decoction of hydrology fire by 1: 8 of medicine gross mass, boil rear 60 minutes, medicinal liquid is leached, by the medicine gross mass 1: 2 adds the decoction of hydrology fire again, boils rear 30 minutes, and medicinal liquid is leached;
2) above-mentioned medicinal liquid is reentered into decocts in clean earth pot to thick, moisture is removed in oven dry, makes the dry product medicine;
3) the dry product medicine is placed in container and adds 60% ethanol 1000ml, add Borneolum Syntheticum powder 10g, and mix homogeneously, bottling and get final product after sterilization.
CN 201110166597 2011-06-21 2011-06-21 Externally applied traditional Chinese medicine composite for treating joint pain caused by rheumatoid arthritis and preparation method thereof Active CN102225125B (en)

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CN104208205A (en) * 2014-09-13 2014-12-17 吕银兰 Dampness-eliminating and cold-dispelling medicinal liquor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1278446A (en) * 1999-06-18 2001-01-03 贺云青 Chinese medicinal composition for cerebrovascular disease, rheumatism and rheumatoid disease
CN1872322A (en) * 2006-04-21 2006-12-06 曾凡铜 A topical powder for the treatment of rheumatism and bony spur
CN101164604A (en) * 2007-06-11 2008-04-23 徐发成 Traditional Chinese medicine for treating arthrosis and preparing method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1278446A (en) * 1999-06-18 2001-01-03 贺云青 Chinese medicinal composition for cerebrovascular disease, rheumatism and rheumatoid disease
CN1872322A (en) * 2006-04-21 2006-12-06 曾凡铜 A topical powder for the treatment of rheumatism and bony spur
CN101164604A (en) * 2007-06-11 2008-04-23 徐发成 Traditional Chinese medicine for treating arthrosis and preparing method thereof

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