CN102089646A - Fluorescence molecular body imaging system and method thereof - Google Patents
Fluorescence molecular body imaging system and method thereof Download PDFInfo
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- CN102089646A CN102089646A CN2009801006943A CN200980100694A CN102089646A CN 102089646 A CN102089646 A CN 102089646A CN 2009801006943 A CN2009801006943 A CN 2009801006943A CN 200980100694 A CN200980100694 A CN 200980100694A CN 102089646 A CN102089646 A CN 102089646A
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- 238000003384 imaging method Methods 0.000 title claims abstract description 20
- 238000000034 method Methods 0.000 title claims abstract description 17
- 238000009826 distribution Methods 0.000 claims description 24
- 230000003287 optical effect Effects 0.000 claims description 14
- 241001494479 Pecora Species 0.000 claims description 5
- 239000004744 fabric Substances 0.000 claims description 5
- 239000011521 glass Substances 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 4
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 3
- 238000000799 fluorescence microscopy Methods 0.000 abstract 4
- 241001465754 Metazoa Species 0.000 abstract 1
- 238000002073 fluorescence micrograph Methods 0.000 abstract 1
- 238000005070 sampling Methods 0.000 abstract 1
- 239000002023 wood Substances 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 2
- 210000002683 foot Anatomy 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000005065 mining Methods 0.000 description 1
- 230000005311 nuclear magnetism Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0064—Body surface scanning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
A fluorescence molecular body imaging system and a method are disclosed. The system comprises a line source exciting device, a rotating platform, a fluorescence imaging device, a profile acquiring device and a computer. The line source exciting device including an exciting source and a line light beam generating unit is arranged at one side of the rotating platform.The rotating platform includes a support used for hanging the imaging object and an electric rotating platform connected to the support. The fluorescence imaging device is arranged at the other side of the rotating platform relative to the light source exciting device and includes a lens and a detector used for sampling the fluorescence image data coming from the imaging object. The detector is arranged at rear of the lens.The profile acquiring device and the fluorescence imaging device are arranged at the same side to sample 3D profile data of imaging object. The computer is connected electrically with the detector and the electric rotating platform and the profile acquiring device separately by an interface controller. The rotating angles of the rotating platform are preset in the computer. The invention can rapidly and effectively induce the fluorescence imaging to animals.
Description
Light point is in not Xiang Xi System and method Mu Collar domains
Originally it is in not Xiang Xi System and method in the light point in small work(picture to be related to sheep molecular imaging Mu Te Do.Now has wood
Molecular imaging wood be utilize or specifically divide in or Fine born of the same parents obtained on living organism stops it is biological stop physiology, pathology phase husband information such as Fine born of the same parents, gene and point in the phase husband information in level and gene function positioning, Fine born of the same parents' life, effect and it is new effective information be provided and analyze her means.At present in as wood is main include as, as with the smooth sheep therein such as nuclear-magnetism picture as having, Wan Radiation to penetrate, high day sensitivity and low cost etc. therefore obtained and rapid.
In as wood seems to utilize picture
Absorb extraneous incidence specific light photon it is complete in light light in light photon.Light light can be obtained in absorption partial photonic to the surface of picture with high performance D phases ha ge oup ed Dev ce conjunction element spies Measuring.F (F uo esce ce o ecu a omog aphy light point is in room imaging) is newest light sheep in resolution ratio good image space method Ju You More but near the position that radiant is irradiated to.The picture information that the nearly Inner of Wan radiants light is not easy to obtain by or Jiu Shi get Measuring is forbidden.The information for more importantly obtaining being imaged whole body each height was usually required every certain height with regard to one week.Yao Door Sheng Jiang Installed with regard to Xu to put the height Potential of radiant and must close raising F T Xiang Xi System.Other tail Number N picture is also mutually N times together together.The raising and same being multiplied of imaging that Ke Now have F T Xiang Xi System degree limit the fast biology Yang Now of F T mono- Xie More as in thing generation.Inner holds
Upper purpose is provided in small work(picture and as the light point of, image height is in not Xiang Xi System and method.
The upper following flitch case light of purpose sheet point is that it is put including my Guang Yuan Installed, spy platform, Xiang Installed are put, a universe in not its spy of Xiang Xi System
Installed put with light source Installed put special one it include light source and the special platform of light beam generation include respiration as the support and a Even of analysis connect support it is special put as Installed in phase described in special another they put of light source Installed include republicanism and collect the spys Measuring devices of the light Mission pictures being imaged out visiting Measuring devices and put in stated Installed and described enter the imaging put as the light Mission pictures and stated Installed of the Installed imagings put as the Installed interface controllers put with collection imaging divide Do Even to meet Measuring devices, spy and Installed and put the Lose of the Inner special angles of spy
Lose go out control institute spy, Xiang Installed Zhi He work order that Installed is put is Ji Guang Mission pictures stop the distribution in picture Inner of reconstruction.
Light source or the solid Inner of optical band great power LED light beam generate an outer Side of Round shapes for being situated between the square light beam of glass thousand generation of an end Round shape other ends and are equipped with a gap Sew.
Light source my light beam generation is with being equipped with one.
Spy is to be equipped with Yi Filter light together.
The phase of Tan Measuring devices one.
Installed puts the picture for connecing the analysis.
Be in expression System optical molecule stop image space Fa Qibao include with lower step Sudden include my light source Installed put, special platform, put as Inspection Measuring Installed, Installed puts the optical molecule of sum and stopped as being that System interface controllers point Do Even connect special platform, put 2 using as 2 Will pictures blame straight 3 light point on special platform in stopping as being that the special spy one of the special platform of System controls is situated between that to stop picture and Wheels that particular-trade being imaged wide for special angle with Installed as Installed is put
Special 36.
0 stops 4 utilizing not method for reconstructing in being distributed in as Inner according to Guang Mission pictures.
Executive Hang Bu Sudden 4 its Bao include the surface of the imaging that Bu Sudden Will Installed are put Xia Yi into a Jiexiu model again Will stop Mo Xing Wan into Jie's finite element Ah to build position as Will Guang Yuan Installed put out Money light, my its position of light source of fixation be irradiated in my light beam of imaging surface to picture in finite element on Ah solve light source and its
Green's letter Number each light sources of distribution Q using the Green's letter Number cutting cloth tried to achieve obtain her Strong degree unknown distributions with Money according to her Strong degree distributions with I obtain distribution in picture Inner.
Due to above flitch case, it has following, sheet due to light source whole body therefore only needs the small work(spies 360 of Will just can be with small work(panorama sheet
City is accelerated as speed with the convenience that the flux for adding this is improved significantly.The 2 special angles for being equipped with spy due to this bright middle Inner are same
Xiang Installed Zhi are He the Number that put of Installed also control therefore this Measuring amount image heights.3rd, this method improves picture because stopping of putting of Xiang Installed rebuilds therefore more be reconstituted in small work(and stop Inner distribution one step.4 due to this Guang Yuan Installed put, Xiang Installed put with small work(spy Ping Tai Installed be set to Jie's non-fit, whole body, 36.
Therefore 0 full Jing Measuring Xi System substantially increase Guang Yuan Measuring devices and Number with convenience big finally.1 is this Shi Yi Mission
Mission 2 be this it is bright in the signals put of Guang Yuan Installed
3 be and light characteristic
4 be the Shi Yi Mission that this is stopped
Mission 5 is 4
6 be the signal that this is stopped
7 be 6 Visual that bows
8 Shi Xiu Measuring obtain height a distribution image
9 Shi Xiu Measuring obtain height b distribution image
0 Shi Xiu Measuring obtain height.The distribution image that height a is obtained according to the Shi Xiu Measuring of distribution image 1
The Shi Xiu Measuring of distribution image 3 that 2 Shi Xiu Measuring obtain height b obtain height.Distribution image this best mode
Below He Mission and this.
This Ming Xi System put 1, the one special platform 2 of small work(, Yi Xiang Installed including Guang Yuan Installed and put 3, Installed and put 4 and 5 as shown.
Guang Yuan Installed put 1 the special platform 2 of small work(one it include light source 11 and light beam generation 12 and light source 1 my light beam generation 12 it is with the light beam for being equipped with Yi Filter light 13 and causing only small work(to stop Inner generate 12 Er Filter removes other.Light source 11 can be with this as indicated with 2
1 can also the solid Inner of optical band great power LED.Light beam generation 12 can be situated between square glass 12 its Will of an end Round shape other ends with one
The 11 light spies gone out stop Inner's with my light source needed for small light light beam Xi Sew 122 can obtain this Ming Xi System in small work(.The wherein m of Xi Sew 122 4 mm unexpectedly.As long as my Guang Yuan Installed put 1 can also other light source Installed put generation Money light light beam foot as being less than mm.
The He mono- Even of support 2 that small work(spy 2 includes the small work(thing of respiration as shown meet the spy 22 of support 2.Small work(thing leads to support 21, and in spy 22, she in the strange hundred logical small work(things in position stops Zhong Xin Shaft overlapping to greatest extent with spy 22.
As Installed put the special platform 2 of the 3 small work(put in Xiang Guangyuan Installed it is another it include a big Number values it is past 3 and one be located at 31 Mining Measuring devices 32 3 small work(spies 2 it is be equipped with together 1 in.32 1 phases in this.
Installed, which puts 4 and puts 3 with the Guang Mission Xiang Installed of Tan Measuring devices 32 Xiang Installed, puts 4 synchronous small work(things.This Zhong Installed put 4 pictures for connecing 5.
The He Installed of 5 interface controller Fen Do Jie Tan Measuring devices 32 put 4 Yu Tan Measuring devices 32 to the Xiang that goes out of small work(surface He Installed put 4 to small work(thing stop rebuild Will stop reconstruct stop Inner distributions in small work(with as form.Jie mouthful Kong Qi Even of special angle 5 that other 5 Inner has spy 22 connect spy 22 in the special platform 2 of small work(in small work(its body of control spy 22 stop according to the special angle spy in 5 Inner with i.e. 360 degree Guang Mission pictures of small work(panorama with.This Ming Xi System go out the Filter of Guang Filter light 13 using light source 1 and removed
My light sources of my light beam generation Yang2Te, which are radiated at, stops that the Filter of Filter light 33 that Inner vacationettes surface penetrates out is removed and the Measuring devices 32 of being visited of light receive 5 and send 5 with the Installed also Lose for putting the synchronous small work(things of 4 Will in vacationette.Connect and see that the special angle of Jie of 5 spy, 22 spy one stops spy 5 and controls Tan Measuring devices 32 to put 4 Number mutually spent up to spy 22 altogether spy 360 stops He Installed.
The surface to obtain small work(thing of her small thing of 5 back projection methods.Most 5 stop method for reconstructing she as to obtain stopping in small work(Inner distribution.
This method stops Bao and includes Yi Xia Bu Sudden
Small work(Will specifically injects small work(and stops Inner to make power.
The 2 small work(things for fixing small work(Will Ma Paralysis blame the straight small work(on spy 2 with support 21 and stop Zhong Xin Shaft overlapping to greatest extent with spy 22.
3 small work(see that 22 spy Guang Yuan Installed of spy put the spy that 1 Chu Money are situated between to vacationette surface spy one under 5 control
Spy 22 stops special as Installed puts aperture that 3 one small work(surface goes out as Will Lose send 5 Installed to put 4 with the small work(thing of stride
Will 5, the spy of spy 22 360 completes Guang Mission pictures.
4 according to Guang Mission pictures using not method for reconstructing small work(stop Inner according to be distributed in 5 its stop Bao and include Bu Sudden Xia Yi
Will Installed put 4 into a Jiexiu model G, Will stops model G Wan into Jie finite element Ah F again on small work(surface.
(Tan Measuring devices 32 to as Will Guang Yuan Installed put out Money light build Wei put Gu Ding Long degree my its position of light source be irradiated to the wide surface of small work(Wheels light beam middle e.Wherein " any " one on e be situated between my letter Number Qi Full is as follows enough
L「 1
With K2e e
" g e Condition light sources are distributed with equal Uniform and energy and power one are situated between not in
Energy force 0 above.
Visit Measuring devices 32 to picture my light source " and its following differential equation of Green's letter Number distribution Green's letter Number cutting cloth Full foots is solved on finite element Ah F
Wherein ") be located at position she be Number be positioned at her absorption of position be Number and equal power oneself know.G Green's letter Number cutting cloth S.Solve Green's letter Number distribution G S of light source
" L " and solve it is a certain positioned at position she
Green's letter Number distribution S.Wherein P is letter Number Qi Full as follows enough
Wherein represent same.Shang Condition P are situated between in other energy forces 0 in her energy force.
Each light source obtained using the Green's letter Number cutting cloth tried to achieve the Inter of her Strong degree unknown distributions I stopping as the six face Xiu Aliu Mian Xiua centers 12...T for stopping AV small Wan.Upper stop seems that stopping of stopping of small work(stops on Ah in six faces where model G and set up her Strong degree.Six Mian Xiua centers
".The same square Array W e as follows of the juice distribution of upper position
Wherein second, J 12...T are that, in her W e of six Mian Xiua centers, my light source is " as follows in its table of her Strong degree arrived in her of six face Xiu A centers
W e J Gw G,
Had Money light sources " and its it is all can be according to the square Array W for setting up following Jie our the Cheng Qizhong vectors b of square Array most Final and representing all Number square Array power laughed at Jie's light source per a line one
Solution domain property equation b A obtain spy Needles and stop the supercentral distribution of Ah in six faces.
The validity sheet of this Ming Xi System and method is following to stop.Docya e ee are used in stopping as shown
3 use the D of N kko 6 2. of Japanese N ko companies with the FF 775 46 33 of Se e ock companies of U.S. with 897 phases 31 of the solid ndo companies of the Measuring devices 2 of FF 840 12 of e e ock companies of U.S..Light characteristic black as indicated at 3 represents 13 light Latent personality presentations
33 light characteristic I represent.
As shown in 47 in stopping Will filled with fatty solution fatty solution " position be Number " 1 3m absorb be the 2m " of Number 0.0 the small work(Bo Li Round posts 6 of Bo Li Round posts 6 it is straight toward 30 height 68m.Glass tubes 7 of the Will filled with u, g mL, Inner toward 3m visits Needles.Will glass tubes 7 are placed in Bo Li Round posts 6 to be similar to stop Inner in small work(and are filled with.The height 3 of the m of light light beam 4 bottom waters of mm and Bo Li Round posts 6 unexpectedly.5 Inner spy 22.
The special The Tan Measuring devices 32 of angle 10 have 36 pictures altogether.Will Xiu Xiang Wan it is small stop A=.5 mX .5mmX .5 m six faces stop Ah.Each 60 Garden Inner in left and right at the center of 1 Chu Money light source Yi Bo Li Round posts 6 are put every Jie of 2m mono- in Guang Yuan Installed.
As shown in 4,5 stop one in the position for being placed on the bottom 38 of Bo Li Round posts 6 she.As shown in 67 stop one in the position for being placed on the bottom 24 of Bo Li Round posts 6 she.Upper Shen Qing Condition are stopped using this method and stop 6 Inner tri- Victoria distributions as 50 T geb a c eco s uc on ech que obtain Bo Li Round posts for Number reconstructions.The Bo Li Round posts that reconstruction is obtained stop 6 Inner each height of distribution in the m 3 of height a 38 m) C 24)
Xiang Fen Do 8 10,13 are effective as fine this Ming Xi System and method.
It is upper it is each in each part, position, Ji Qi Even connect all be the upper-part in this bright skill flitch case that can change change and equivalent Jiao Change are not precluded within outside this guarantor.
Claims (1)
- It is required that 1, optical molecule stop Xiang Xi System its spy be it put including Guang Yuan Installed, spy platform, Xiang Installed Zhi, Installed put andGuang Yuan Installed put special one it include light source and light beam generates sheepSpecial platform includes the support of respiration picture He Yi Even meet the spy of support "As Installed another they put in the mutually special platforms put of my light source Installed include republicanism collect the spy Measuring devices of the light Mission pictures being imaged out inInstalled put as the Installed interface controller point Do Even put with collection imaging connect visit Measuring devices, special and Installed put the special special angles of Inner Lose enter as the Installed imagings put light Mission pictures andThe Lose for the imaging that Installed is put go out control the special platform, the work order put with Installed is put as Installed and aperture picture stop reconstruction as Inner distribution.2nd, a desired optical molecule is stopped Xiang Xi System its spy and isLight source or the solid Inner of optical band high-power LE light beams generate an outer Side of Round shapes for being situated between the square glass light beam generation sheep of an end Round shape other ends and are equipped with a gap Sew.3rd, require that 1 optical molecule is stopped Xiang Xi System its spy and isLight beam of light source generation is equipped with Yi Filter light.4th, require that 2 light point is in not its spy of Xiang Xi SystemLight beam of light source generation is to be equipped with Yi Filter light together.5th, require that 1 or 2 or 3 or 4 light point is that spy is in not its spy of Xiang Xi System and is equipped with one together.6th, require or 2 or 3 or 4 optical molecule stops Xiang Xi System its spy and is the phase of Suo Shu Measuring devices one. 7th, require that 5 optical molecule stops Xiang Xi System its spy and is the D phases of Tan Measuring devices one.8th, its special Yu Installed puts the picture connect in not Xiang Xi System for requirement or 2 or 3 or 4 or 7 light point.9th, require that 5 light point is in not its spy of Xiang Xi SystemInstalled puts the picture for connecing analysis.10th, require that 6 optical molecule is stopped Xiang Xi System its spy and isInstalled puts the picture connect., be that System light point is included with lower step Sudden in not image space Fa Qibao in expression,1 stops Xiang Xi System interface controller Fen Do Even including the optical molecule that my Guang Yuan Installed are put, spy, Xiang Installed Zhi, Installed put and analysed meets special platform, Xiang Installed Zhi He Installed is put2 utilize picture2 Will pictures are straight on special platform3 optical molecules stop as be System controls spy spy Te Pingtaite mono- be situated between it is special stop aperture picture that particular-trade being imaged withTe Pingtaite 360.Stop4 visit Needles in being distributed in as Inner according to Guang Mission pictures using not method for reconstructing.12 require that 1 optical molecule stops image space Fa Qite and is that its bag is included with lower step Sudden in Executive rows step Sudden 4The surface for the imaging that Will Installed are put is situated between into one, and what dinner is not model, then Will stops Mo Xing Wan into Jie finite element AhTo as the Will Guang Yuan Installed light put out build position, its position of the light source of fixation be irradiated to imaging analysis three surfaces light beam inVisit Measuring devices to picture institute finite element on Ah solve light source and its Green's letter Number be distributedEach light source is obtained using the Green's letter Number cutting cloth tried to achieve In the distribution as Inner.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2009/000717 WO2010148540A1 (en) | 2009-06-26 | 2009-06-26 | Fluorescence molecular body imaging system and method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN102089646A true CN102089646A (en) | 2011-06-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN2009801006943A Pending CN102089646A (en) | 2009-06-26 | 2009-06-26 | Fluorescence molecular body imaging system and method thereof |
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| CN (1) | CN102089646A (en) |
| WO (1) | WO2010148540A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670180A (en) * | 2012-06-06 | 2012-09-19 | 北京大学 | Vertical type rotary fluorescence molecular imaging system |
| CN106796145A (en) * | 2014-07-09 | 2017-05-31 | 加利珀生命科学股份有限公司 | Extracted from the pure spectrum of biological sample |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102096914B (en) * | 2011-01-26 | 2012-10-10 | 中国科学院自动化研究所 | Method for eliminating interference of autologous florescence from biological fluorescence image |
| CN102512193B (en) * | 2011-11-15 | 2014-10-08 | 华中科技大学 | Double-mode in-vivo imaging system and method based on wavelet data compression |
| CN103720459B (en) * | 2013-12-27 | 2015-11-04 | 北京航空航天大学 | A kind of based on single slip ring and controlled in wireless exciting light scanning device for fluorescent molecule fault imaging and method |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6894303B2 (en) * | 2000-06-29 | 2005-05-17 | Essex Electro Engineers, Inc. | Method and apparatus for radiographic imaging |
| DE10132808B4 (en) * | 2001-07-06 | 2005-07-28 | Siemens Ag | Optical diagnostic system for small animal imaging |
| CN101361651B (en) * | 2008-09-19 | 2010-04-07 | 清华大学 | Fluorescent molecule fault imaging device |
| CN101396262B (en) * | 2008-10-31 | 2010-06-23 | 清华大学 | Fluorescent molecule tomography rebuilding method based on linear relationship |
-
2009
- 2009-06-26 CN CN2009801006943A patent/CN102089646A/en active Pending
- 2009-06-26 WO PCT/CN2009/000717 patent/WO2010148540A1/en active Application Filing
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670180A (en) * | 2012-06-06 | 2012-09-19 | 北京大学 | Vertical type rotary fluorescence molecular imaging system |
| CN102670180B (en) * | 2012-06-06 | 2013-09-18 | 北京大学 | Vertical type rotary fluorescence molecular imaging system |
| CN106796145A (en) * | 2014-07-09 | 2017-05-31 | 加利珀生命科学股份有限公司 | Extracted from the pure spectrum of biological sample |
| US10126242B2 (en) | 2014-07-09 | 2018-11-13 | Caliper Life Sciences, Inc. | Pure spectrum extraction from biological samples in fluorescence multispectral imaging |
| CN106796145B (en) * | 2014-07-09 | 2019-09-06 | 加利珀生命科学股份有限公司 | For extracting the method and system of the pure spectrum of the fluorescent dye in sample |
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| Publication number | Publication date |
|---|---|
| WO2010148540A1 (en) | 2010-12-29 |
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Application publication date: 20110608 |