CN101869225B - Feed additive for improving pregnancy rate of sows and preparation method thereof - Google Patents
Feed additive for improving pregnancy rate of sows and preparation method thereof Download PDFInfo
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- CN101869225B CN101869225B CN2010102009642A CN201010200964A CN101869225B CN 101869225 B CN101869225 B CN 101869225B CN 2010102009642 A CN2010102009642 A CN 2010102009642A CN 201010200964 A CN201010200964 A CN 201010200964A CN 101869225 B CN101869225 B CN 101869225B
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Abstract
The invention discloses a feed additive for improving the pregnancy rate of sows and a preparation method thereof. The feed additive consists of the following components in part by weight: 30 to 40 parts of Chinese taxillus twig, 20 to 30 parts of Chinese dodder seed, 5 to 8 parts of astragalus, 5 to 8 parts of malaytea scurfpea fruit, 0.5 part of vitamin A, 2 parts of vitamin E, 0.8 part of folic acid, and the balance of zeolite powder. After being mixed together, the Chinese taxillus twig, the Chinese dodder seed, the astragalus and the malaytea scurfpea fruit are subjected to cell-level fine crushing to make the grain diameter thereof to be 25 to 40 microns. As medicament effects of every component of the feed additive coordinate and interact, the feed additive has the advantages of maintaining health of the organisms of the sows, increasing the nidation of zygotes, reducing the stillbirth rate, increasing the number of born alive piglets and healthy piglets, and obviously increasing the pregnancy rate of thesows after application, along with low addition volume, good effect, no residue, and no toxic or side effects.
Description
Technical field
The present invention relates to a kind of feed addictive, particularly relate to a kind of Chinese herbal medicine composite feed additive that can improve pregnancy rate of sows.
Background technology
According to statistics, the numerous sow of China's ability was more than 4,900 ten thousand in 2009, ranked first in the world.But the reproductive performance of China sow is low, and the annual average childbirth tire number of domestic every sow is 1.7 tires, and the U.S. reaches 2.28 tires, and the North America is 2.42 tires, and Brazil is 2.5 tires, and Japan is 2.43 tires; Every provides weanling pig China only 17 sow year, and the U.S. is 20, and the North America is 23.26, and Brazil is 25.96, and Japan is 24.92; The piglet survival rate is also lower, and China is 84%, and the U.S. is 95%.The reproductive performance of sow receives the influence of many factors such as heredity, nutrition, environment, health status, and we think the key that improves pregnancy rate of sows, and except management factors, nutrition is most important factor.Want to improve the pregnancy rate of sow, we will prevent miscarriage from sow and start with, and by means of suitable technique and product, increase the sow number of eggs ovulated and produce the young number of living with raising ovum quality, reduction still birth rate, increase.
For this reason, part scholar changes the research thinking, sets about utilizing Chinese herbal medicine to improve pregnancy rate of sows, has obtained certain effect.Chinese herb feed additive has function such as promote growth, prevent disease, prevent miscarriage, use the back to the animals and animal product noresidue, have no side effect, be difficult for developing immunity to drugs.From the modern nutriology theory analysis, the contained alkaloid of Chinese herbal feed additive, polysaccharide, glucoside, volatile fatty acid, organic acid etc. all are bioactivators, to the sow breeding good action of having prevented miscarriage.There is the scholar to utilize Chinese herbal medicine to improve pregnancy rate of sows, though obtained certain effect, exists the addition height, drug effect is slow, waste is serious and problems such as palatability difference, thereby cause pig to produce few food or food refusal behavior, do not reach desirable effect.
We are when having accepted multinomial provinces and cities ground scientific research project; For how utilizing Chinese herbal medicine to carry out a large amount of practical technique researchs; Comprise for lixiviate, the cell grade micro mist is broken and common pulverizing etc. is compared, and finds to adopt suitable cell grade micro mist broken, and is poor unlike extracting effect; Not only having reduced addition but also the definite effect simultaneously that reduces cost, is the means of utilizing Chinese herbal medicine preferably.
Broken being meant with the biological cell broken wall of cell grade micro mist is the comminution process of purpose, and it is not purpose with the smashing fineness, but pursues the sporoderm-broken rate of cell.Broken through the cell grade micro mist, can the medium particle diameter of former green material be brought up to more than 300 orders from 40～80 orders of traditional handicraft, for general medicinal material, the breaking-wall cell rate under this fineness condition is greater than 95%.Cell intracellular active ingredient behind broken wall fully comes out, the rate of release and the burst size of medicine can significantly improve.The medicinal material particle is after the cell grade micro mist is broken, and microscopically is observed only has the minute quantity intact cell to exist.The cell grade micro mist is broken to mainly contain following advantage aborning: (1) increases the drug absorption rate, improves the Chinese traditional medicine biology utilization rate: after Chinese medicine cell grade micro mist was broken, the main pharmacodynamics composition of medicine was distributed in the cell and cytoplasm usually, and being main in the cell.Active ingredient comes out in its cell behind the breaking-wall cell, so drug effect increases substantially, and onset speed is fast; (2) help the retains biological activity composition, improve drug effect: in the broken process of cell grade micro mist, can not produce superheating phenomenon through control; Even can under low-temperature condition, carry out; And pulverizing speed is fast, helps keeping the bioactive ingredients and the various nutritional labeling of non-refractory, thereby improves drug effect; (3) conservation, be convenient to use: Chinese medicine is after the cell grade micro mist is broken, and available smaller dose obtains former prescription curative effect.General medicine can no longer pass through processing such as lixiviate, decoction after the cell grade micro mist is broken, reduced loss of active ingredients in the production link, has maximally utilised raw material, so this technology is suitable for the pulverizing of rare Chinese medicine, and owing to the increase of fineness.Can improve mouthfeel, be convenient to take.On the other hand, be in totally-enclosed dustless system, to carry out because of the cell grade micro mist is broken, can effectively avoid outside contamination, make the content of microorganisms of product and dust be able to control.
And vitamin A, E, folic acid etc. all are important nutrient required in the pregnant process.When wherein sow is deficient in vitamin A; Conception rate can occur descends; Performance oestrus undesired, difficult labour, miscarriage, stillborn foetus, weak tire, monster and retention of afterbirth etc. suitably improve the addition of diet vitamin A, can improve sow nest litter size and number pigs weaned; Vitamin E and reproductive capability are closely related, can promote the generation of thyroid-stimulating hormone and corticotropin and promoting sexual gland hormone, strengthen the ovary function; Make ovarian follicle increase lutein cell, replenishing vitamins E in the sow daily ration can not only improve conception rate; Reduce foetal death, increase the nest litter size, and can strengthen the anti-stress ability of piglet; Piglet is dead before reducing wean, shortens sow and weans to inter oestrual period.Research shows, the sow nest litter size of the high-level vitamin E of feeding, to produce the young number of living all higher, and mammitis-hysteritis-agalactia syndrome (MMA) incidence of disease is lower.The ovary function descends when sow is deficient in vitamin E, and sexual cycle is unusual, can not be fertilized the unusual or appearance of embryonic development; Folic acid has important effect to the reproductive performance of keeping sow with promotion fetus early development.Its major function is the coenzyme in various different enzyme systems, participates in the synthetic of purine, so quite important to synthesizing of DNA, RNA.Keeping aspect the Steady breed function of sow, can improve the nest litter size, keep good lactation power, prevent that lactation is disorderly.The sow daily ration adds folic acid can improve embryo survival, the stable nest litter size that improves.When lacking folic acid, stillborn foetus can appear.
Summary of the invention
Technical problem to be solved by this invention is: overcome the deficiency of prior art, a kind of feed addictive that is used to improve pregnancy rate of sows and preparation method thereof is provided.
The present invention solves the technical scheme that its technical problem takes: this feed addictive that is used to improve pregnancy rate of sows is composed of the following components, and the total weight parts of said each component is 100 parts, wherein,
All the other are zeolite powder;
Said parasitic loranthus, the seed of Chinese dodder, the Radix Astragali and Psoralea corylifolia mix after the cell grade micro mist is broken to particle diameter is 25～40 microns.
Further, by weight: the Radix Astragali according to the invention is that 5 parts, Psoralea corylifolia are 5 parts.
Further, by weight: parasitic loranthus according to the invention is that 30 parts, the seed of Chinese dodder are 20 parts.
The preparation method that the present invention is used to improve the feed addictive of pregnancy rate of sows is: with weight portion is that 30～40 parts parasitic loranthus, 20～30 parts the seed of Chinese dodder, 5～8 parts the Radix Astragali, 5～8 parts Psoralea corylifolia are mixed; After the cell grade micro mist is broken to particle diameter is 25～40 microns; Adding weight portion again is 0.5 part vitamin A, 2 parts vitamin E, 0.8 part folic acid and zeolite powder; Mix, the total amount of said parasitic loranthus, the seed of Chinese dodder, the Radix Astragali, Psoralea corylifolia, vitamin A, vitamin E, folic acid and zeolite powder is 100 parts.
Further, the weight portion of the Radix Astragali according to the invention is 5 parts, and the weight portion of Psoralea corylifolia is 5 parts.
Further, the weight portion of parasitic loranthus according to the invention is 30 parts, and the weight portion of the seed of Chinese dodder is 20 parts.
The present invention is on the basis with reference to traditional Chinese veterinary medicine and modern nutriology principle; Formulated Chinese herbal medicine composite feed additive; Basic metabolism and physiological function through the adjustment sow; Safeguard the health of sow body, the endocrine level of adjustment sow increases the zygote implantation, reduces still birth rate, increases and produce live young number and strong young number.Positive beneficial effect of the present invention is:
(1) theoretical according to Chinese medicine, reproductive performance and the renal function of animal are closely related.The kidney negative and positive are in harmonious proportion, and essence and blood is full, and reproductive capacity is then strong; If imbalance of yin and yang, the essence and blood loss, reproductive capacity is then low or useless exhausted.The drug effect coordination linkage of each component in the feed addictive of the present invention can be safeguarded the health of sow body after the application, increase the zygote implantation, reduce still birth rate, increase and produce live young number and strong young number, obviously improves the pregnancy rate of sow.
In prescription of the present invention:
Parasitic loranthus: property is flat, and bitter, sweet is returned liver, kidney channel, has filling liver kidney, strengthening the bones and muscles, an effect wet, antiabortive unit of dispeling the wind, and is used to treat that arthralgia due to wind-dampness, soreness and weakness of waist and knees, muscles and bones are unable, uterine bleeding is through many, blood leaking in gestation, fetal irritability;
The seed of Chinese dodder: warm in nature; It is sweet to distinguish the flavor of; Return liver, kidney channel, have nourishing liver and kidney, controlling nocturnal emission with astringent drugs contract urine, antiabortive, make eye bright, the effect of antidiarrheal, cure mainly impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen and suffer from a deficiency of the kidney and rush down;
The Radix Astragali: warm in nature, it is sweet to distinguish the flavor of, and returns lung, the spleen channel, has the effect of benefiting qi and raising yang, strengthening exterior and reducing sweat, inducing diuresis for removing edema, detoxification myogenic, can treat the disease of all Qi and blood deficiencies, like diseases such as splenasthenic diarrhea, cough due to deficiency of the lung, metroptosis, spontaneous perspiration, night sweat, oedema;
Psoralea corylifolia: warm in nature; Flavor is hot, bitter; Return kidney, pericardium, spleen, stomach warp; Lung channel, have tonify the kidney and support yang, promoting inspiration to relieve asthma, warming spleen and stopping diarrha effect, cure mainly that the insufficiency of the kidney yang, below element deficiency and cold, waist knee crymodynia, impotence essence, frequent micturition, the enuresis, the failure of the kidney in receiving air, void are breathed heavily incessantly, disease such as speen-kidney dificiency, stool are rushed down for a long time; And vitamin A, E, folic acid etc. all are important nutrient required in the pregnant process.
(2) Chinese herbal medicine composite feed additive of the present invention, required addition few (generally 0.08～0.12% interpolation by weight percentage gets final product in feed), effective.Problems such as have adding proportion high (the general percentage by weight that adds is more than 0.5%) in the traditional Chinese medicine interpolation process, cost is high, drug effect is slow, waste is serious and process technology is improper; And the present invention adopts the broken technology of cell grade micro mist (particle diameter of additive is 25～40 microns) that effective ingredient is directly come out; The absorption and the bioavilability of medicine have been improved greatly; Shorten the drug effect time, not only reduce addition but also reduce cost, simultaneously definite effect.
(3) feed addictive of the present invention, has no side effect at noresidue.The antibiotic that mostly contains chemical synthesis in the conventional feed, even hormone etc., thereby these compositions very easily cause the secondary residual human health that jeopardizes of poison, have also polluted ecological environment.And in feed, add feed addictive of the present invention; All adopt non-harmful natural Chinese medicinal herb; Do not add any chemical synthesis antiseptic and poisonous and harmful substance, do not produce the cross-resistance of people and animals' concomitant medication, thoroughly avoided the secondary residual drawback of conventional feed poisoning.
The specific embodiment
In following examples, feed addictive herbal raw material of the present invention is purchased in Anhui Province Bozhou City letter Li De pharmaceutcal corporation, Ltd.
Embodiment 1
With parasitic loranthus, the seed of Chinese dodder, the Radix Astragali, Psoralea corylifolia oven dry, weighing parasitic loranthus 300 grams, the seed of Chinese dodder 200 restrain respectively then, the Radix Astragali 50 restrains, Psoralea corylifolia 50 grams, section arrangement then respectively; Mix, mixed mixture is at first carried out 60 order coarse crushings, it is broken to adopt QYF type fluidized bed air flow crusher to carry out the cell grade micro mist then; It is 25～40 microns (approximately fineness is 350～500 orders) that mixture is crushed to average grain diameter; And the vitamin A micro-capsule 5 that adds 500,000 IU/ gram again restrains 50% vitamin E powder, 20 grams, 99% folic acid 8 grams; Add carrier zeolite powder 367 grams (fineness is 100 orders) again; Total amount reaches 1000 grams, mixes once more, promptly obtains feed addictive of the present invention.
Embodiment 2
The raw material and the weight thereof that add in the present embodiment are respectively: vitamin A micro-capsule 5 grams of parasitic loranthus 400 grams, the seed of Chinese dodder 300 grams, the Radix Astragali 80 grams, Psoralea corylifolia 80 grams, 500,000 IU/ gram; 50% vitamin E powder, 20 grams; 99% folic acid 8 grams and carrier zeolite powder 107 grams (100 order fineness); Make total amount reach 1000 grams, according to preparing feed addictive of the present invention with embodiment 1 identical preparation method.
Embodiment 3
The raw material and the weight thereof that add in the present embodiment are respectively: vitamin A micro-capsule 5 grams of parasitic loranthus 350 grams, the seed of Chinese dodder 250 grams, the Radix Astragali 70 grams, Psoralea corylifolia 60 grams, 500,000 IU/ gram; 50% vitamin E powder, 20 grams; 99% folic acid 8 grams and carrier zeolite powder 237 grams (100 order fineness); Make total amount reach 1000 grams, according to preparing feed addictive of the present invention with embodiment 1 identical preparation method.
Application examples 1
Test period: test was since on June 10th, 2004; October 12 in 2004 end of day; 124 days test periods are (because surplus the pig farm scale sow 500, the test pig sample size is many, so can not once obtain testing farrowing sow required the time; Therefore we select conceived fate is close in the stage sow as sample, and 104 days of more single sow experimental period 124 days test periods are long).
Test place: Xu Shan plant of Jiaxing City food meat Co., Ltd.
The selection of test pig and grouping: select 36 of parity, body weight, length that conceived fate is close * good binary multiparity sow, be divided into 2 processed group at random, i.e. control group and test group.Each processed group is established 3 repetitions, and each repeats 6.
Basal diet prescription and nutrient content: as shown in table 1.
The test daily ration: the additive that embodiment 1 is prepared is that 0.1% consumption substitutes 0.1% zeolite powder in the basal ration prescription as the test daily ration according to percentage by weight.
Table 1 basal diet prescription and nutrient composition content
Annotate: contain in every kilogram of feed: the rope A 12000IU that supports one's family, vitamin D 1500IU; Below be milligram: vitamin E 45, vitamin K
32, Cobastab
12, Cobastab
26, Cobastab
120.025, biotin 0.2, folic acid 4, pantothenic acid 25, nicotinic acid 50; Cu 5, and Zn 75, and Fe 80, and Mn 10, and Se 0.25, and I 0.3, choline 500,15% aureomycin 300.Wherein DE, Lys, Met+Cys and Thr are calculated value, and all the other are measured value.
Feeding and management: pig house carries out disinfection before the test, promptly gets into after test pig is divided into groups and just tries the phase.The sow of control group is used basal diet feeding, the sow service test daily ration feeding of test group.Stopped using the feed that contains feed addictive of the present invention in preceding 10 days by theoretical date of parturition.Other scheme is carried out according to pig farm Routine Management program.If disease occurs, carry out record and treatment in time.
Performance test: produce the young number of living, nest product stillborn foetus number (the weak tire that gets off not surviving basically is also contained in interior) for the nascent litter weight of unit record nest, litter size, nest with the nest; And calculate average birth weight, average nest product young number alive, average nest product stillborn foetus number, still birth rate, and add up above data.
Data: adopt SPSS (16.0) that data are handled, and carry out one-way analysis of variance and least significant difference method (LSD) check.Data are with average ± standard deviation (X ± SD) expression.
Test result:
(1) interpolation feed addictive of the present invention is as shown in table 2 to the result that the average nest of sow produces stillborn foetus number and still birth rate influence:
Table 2
| Group | Average nest produces stillborn foetus number (head) | Still birth rate (%) |
| Control group | 1.11±0.47 A | 10.15±0.42 A |
| Test group | 0.44±0.51 B | 4.06±0.47 B |
Annotate: same column shoulder motes lowercase difference person significant difference (p＜0.05), capitalization difference person difference is remarkable (p＜0.01) extremely, below each epiphase same.
Visible by table 2, the average nest of test group sow produces the stillborn foetus number and has reduced by 60.36% (p＜0.01) than control group; Still birth rate has reduced by 60% (p＜0.01) than control group.
(2) interpolation feed addictive of the present invention is as shown in table 3 to the result that the average nest of sow produces live young number and the average birth weight influence of piglet:
Table 3
| Group | Average nest produces the young number (head) of living | The average birth weight of piglet (kg) |
| Control group | 9.78±0.81 a | 1.17±0.42 |
| Test group | 10.39±0.92 b | 1.21±0.86 |
Visible by table 3, the average nest of test group sow produces the young number of living and has improved 6.24% (p＜0.05) than control group; The average birth weight of piglet has improved 3.42% than control group, and difference is remarkable (p＞0.05) not.
Can know that by above-mentioned test data behind the interpolation feed addictive of the present invention, the average nest of test group sow produces the stillborn foetus number and reduced by 60.36% (p＜0.01) than control group in the sow daily ration; Still birth rate has reduced by 60% (p＜0.01) than control group; Average nest produces the young number of living and has improved 6.24% (p＜0.05) than control group; The average birth weight control group of piglet has improved 3.42%, and difference is remarkable (p＞0.05) not.In sum, adding feed addictive of the present invention improves significantly to the pregnancy rate of sow.
Application examples 2
Test period: the test since on June 20th, 2007, October 22 in 2007 end of day, 124 days test periods.
Test place: the just flat plant in Xiaoshan, Hangzhou.
The selection of test pig and grouping: select 18 of parity, body weight, length that conceived fate is close * big binary multiparity sow, be divided into 2 processed group at random, i.e. control group and test group.Each processed group is established 3 repetitions, and each repeats 3.
The test daily ration: the additive that utilizes embodiment 2 to prepare is that 0.1% zeolite powder in the basal ration prescription of 0.1% consumption substitution tables 1 is as the test daily ration according to percentage by weight.
Basal diet, process of the test processing and data acquisition and data processing method are with application examples 1.The sow of control group is used basal diet feeding, the sow service test daily ration feeding of test group.
Test result:
(1) interpolation feed addictive of the present invention is as shown in table 4 to the result that the average nest of sow produces stillborn foetus number and still birth rate influence:
Table 4
| Group | Average nest produces stillborn foetus number (head) | Still birth rate (%) |
| Control group | 1.33±0.50 A | 12.58±0.44 A |
| Test group | 0.33±0.50 B | 3.13±0.47 B |
Visible by table 4, the average nest of test group sow produces the stillborn foetus number and has reduced by 75.19% (p＜0.01) than control group; Still birth rate has reduced by 75.12% (p＜0.01) than control group.
(2) interpolation feed addictive of the present invention is as shown in table 5 to the result that the average nest of sow produces live young number and the average birth weight influence of piglet:
Table 5
Visible by table 5, the average nest of test group sow produces the young number of living and has improved 9.65% (p＜0.05) than control group, and the average birth weight control group of piglet has improved 2.90%, and difference is not significantly (p＞0.05) all.
Can know that by above-mentioned test data behind the interpolation feed addictive of the present invention, the average nest of test group sow produces the stillborn foetus number and reduced by 75.19% (p＜0.01) than control group in the sow daily ration; Still birth rate has reduced by 75.12% (p＜0.01) than control group; Average nest produces the young number of living and has improved 9.65% (p＜0.05) than control group; The average birth weight control group of piglet has improved 2.90%, and difference is remarkable (p＞0.05) not.In sum, adding feed addictive of the present invention improves significantly to the pregnancy rate of sow.
Claims (6)
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| CN103494002B (en) * | 2013-08-27 | 2015-12-09 | 安徽省瑞森生物科技有限责任公司 | One sow feed period of pregnancy and preparation method thereof |
| CN104839477A (en) * | 2015-04-30 | 2015-08-19 | 新昌县大成生物科技有限公司 | Feed additive for pregnant sows |
| CN105325727A (en) * | 2015-11-20 | 2016-02-17 | 衡阳市富矿饲料添加剂有限公司 | Plant feed additive for controlling counterbalanced growth of replacement gilts and preparation method |
| CN106962285A (en) * | 2017-05-12 | 2017-07-21 | 巴马原种香猪农牧实业有限公司 | A kind of feeding and management method of period of pregnancy sow |
| CN114601062B (en) * | 2022-04-26 | 2023-07-18 | 华南农业大学 | Feed for pregnant sows and application thereof |
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| CN1269965A (en) * | 1999-04-09 | 2000-10-18 | 苏伯严 | Method for increasing farrowing amount of sow |
| CN1772117A (en) * | 2005-10-31 | 2006-05-17 | 李顺定 | Nephrosis treating Chinese medicine boneyed bolus and its prepn process |
| CN101690551A (en) * | 2009-09-29 | 2010-04-07 | 上海威奇特畜牧饲料有限公司 | Sow miscarriage prevention feed |
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| CN1269965A (en) * | 1999-04-09 | 2000-10-18 | 苏伯严 | Method for increasing farrowing amount of sow |
| CN1772117A (en) * | 2005-10-31 | 2006-05-17 | 李顺定 | Nephrosis treating Chinese medicine boneyed bolus and its prepn process |
| CN101690551A (en) * | 2009-09-29 | 2010-04-07 | 上海威奇特畜牧饲料有限公司 | Sow miscarriage prevention feed |
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