CN101194836B - Method and device for eliminating interference in bio-electrical impedance measurement - Google Patents
Method and device for eliminating interference in bio-electrical impedance measurement Download PDFInfo
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- CN101194836B CN101194836B CN2006101610861A CN200610161086A CN101194836B CN 101194836 B CN101194836 B CN 101194836B CN 2006101610861 A CN2006101610861 A CN 2006101610861A CN 200610161086 A CN200610161086 A CN 200610161086A CN 101194836 B CN101194836 B CN 101194836B
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Abstract
The invention discloses a method for eliminating inference in the process of biological electrical impedance measurement, which comprises receiving and magnifying the voltage signal on measured parts of a human body and current signal on a sampling resistance of series circuit on the measured part of the human body, carrying out fast Fourier algorithm to the current signal and the voltage signal which are converted by the A/D, and extracting target current signal and target voltage signal which meet the calculation condition of biological electrical impedance. The invention further discloses a device for eliminating inference in the process of biological electrical impedance measurement. Applying the invention, the current signal and the voltage signal of the resistance of the measured part of the human body can be purely reflected, the signal error is reduced, and the inference signal which is generated by self-hardware in the process of measurement can be eliminated at a much greater extent.
Description
Technical field
The present invention relates to the bio-electrical impedance measuring technical field, be specifically related to eliminate in a kind of bio-electrical impedance measuring interferential method and apparatus.
Background technology
Electrical impedance tomography (electrical impedance tomography, EIT) be according to " different tissues has different electrical impedance in the human body " this physical principle, by injecting little safe current to human body, the current potential of measuring body surface is rebuild the electrical impedance distribution image of inside of human body, is a new direction of medical imaging technology.
The EIT technology has a lot of advantages, the physiological function that previously studies show that some tissue changes the variation (as: tissue hyperemia and discharge etc.) that can cause tissue impedance, some histo pathological change also can cause the variation (as canceration etc.) of tissue impedance, and these information will embody in the EIT image.So EIT has the character of functional imaging, this technology is harmless to the human body noinvasive, measures easyly, is being with a wide range of applications for the secular image of patient monitoring this respect, and these are that present most clinical imaging means are difficult to accomplish; These characteristics that technology cost is low, expense is low also are fit to carry out medical treatment generaI investigation widely very much simultaneously.
The electrical impedance tomography system include data measurin system (Data Measurement System, DMS) and image reconstruction software two large divisions.The effect of data measurin system is exactly to demodulate the signal of telecommunication that the antimer internal impedance distributes under the sinusoidal signal excitation that driving source produces from body surface measurement, provides data for the impedance image restructing algorithm behind analogue signal-digital signal conversion (A/D conversion) and date processing.
In EIT, the effect of driving source is to produce to put on the exciting electrode to the sinusoidal excitation of human body safety and with the certain range of excitation pattern; The major function of data measurin system is to obtain body surface electric signals under the sinusoidal signal excitation with certain measurement pattern from measurement electrode, adopts demodulation techniques to extract the distributed intelligence of reflection imageable target internal impedance after amplifying, and uses for algorithm reconstruct impedance image; Control circuit mainly is responsible for the parameter and the pattern setting of driving source and measuring circuit as the interface circuit between computer and driving source and measuring circuit, and functions such as correction and calibration; Functions such as computer is mainly totally controlled, date processing, image reconstruction, pictorial display.
Present stage is carried out the measurement of bio-electrical impedance to human body method mainly comprises step: the constant current sine wave output encourages described tested position by the test electrode that is arranged on tested position; Obtain the current value and the magnitude of voltage at described tested position; Carry out analog-to-digital conversion after described current value and magnitude of voltage amplified, and definite target current value and target voltage values; Utilize described target current value and target voltage values to calculate the bio-electrical impedance at described tested position; Described electrical impedance information carry out legendization, generate legend information.
In the above measuring method, can described legend information reflect correctly that the electrical impedance at the tested position of human body changes, and key is the current signal that obtains and the degree of purity of voltage signal.Above-mentioned measuring method does not relate to eliminates this interfering signal, current signal that is obtained and voltage signal many interfering signals of mixing inevitably; In addition, the hardware components of measuring employing can produce sum of errors and disturb in measuring process, as: the surface potential signal errors that the contact resistance that attachment of electrodes causes produces, the interfering signal that produces when various instruments are worked etc.; Finally causing carrying out electrical impedance, to calculate the current signal and the voltage signal degree of purity that are utilized not enough, also promptly can not accurately reflect the distribution of impedance at the tested position of human body, causes the undesirable of imaging precision, can't be accurately change of illness state in the antimer truly.
Summary of the invention
In view of this, the purpose of this invention is to provide a kind of effective elimination interfering signal, bioelectric impedance data measuring method and system that precision is high.
A kind of bioelectric impedance data measuring method provided by the invention is achieved in that
Eliminate interferential method in a kind of bio-electrical impedance measuring, described method comprises step:
Obtain and amplify current signal on the sample resistance on the polyphone circuit at the voltage signal at the tested position of human body and the tested position of described human body;
Current signal and voltage signal through analog-to-digital conversion are carried out fast fourier transform, described current signal and voltage signal are generated harmonic spectrum, according to the threshold value that is provided with by exciting signal frequency scope and signal energy spectrum described current signal and voltage signal are carried out filtering screening, extract the target current signal and the target voltage signal that satisfy the bio-electrical impedance design conditions.
The step of obtaining and amplifying the current signal on the sample resistance on the polyphone circuit at the voltage signal at the tested position of human body and the tested position of described human body comprises:
Standard sample resistance on the series circuit at the first high impedance amplifier and described tested position is arranged in parallel, obtaining the current signal on the series circuit of described tested position, the impedance of described high impedance amplifier be at least described sample resistance impedance 10
6Doubly;
The second high impedance amplifier is linked to each other with second test electrode with first test electrode that is arranged on both sides, described tested position, to obtain the voltage signal at described tested position.
To before carrying out fast fourier transform through the current signal of analog-to-digital conversion and voltage signal, further comprise: when described numerical value through current signal after the analog-to-digital conversion and voltage signal is not within preset range, adjust the described first high impedance amplifier and the second high resistant Amplifier Gain.
Before obtaining and amplifying current signal on the sample resistance on the polyphone circuit at the voltage signal at the tested position of human body and the tested position of described human body, further comprise: described current signal and voltage signal are carried out the pressure-limit current-limit pretreatment.
The pretreated method of described pressure-limit current-limit is specially:
Detect the current value and the magnitude of voltage of described current signal and voltage signal respectively, when detecting described current value or magnitude of voltage and exceed predetermined threshold value, disconnect and connecting.
The invention also discloses in a kind of biologic resistance measurement and eliminate interferential device, described device comprises:
High impedance amplifier, the sample resistance current signal on the polyphone circuit that is used to obtain the voltage signal at the tested position of human body and be arranged on the tested position of human body;
The fast Flourier processing unit, link to each other with described high impedance amplifier, utilize fast fourier algorithm that described current signal and voltage signal are handled, described current signal and voltage signal are generated harmonic spectrum, according to the threshold value that is provided with by exciting signal frequency scope and signal energy spectrum described current signal and voltage signal are carried out filtering screening, extract the target current signal and the target voltage signal that satisfy the bio-electrical impedance design conditions.
Described high impedance amplifier comprises:
The first high impedance amplifier comprises two inputs and an outfan, and described two inputs link to each other with the two ends of described sample resistance respectively, is used to obtain and amplify the current signal of the described standard sample resistance of process;
The second high impedance amplifier, comprise two inputs and an outfan, described two inputs link to each other with second test electrode with first test electrode that is arranged on both sides, the tested position of human body respectively, are used to obtain and amplify the voltage signal of both sides, the tested position of described human body.
The input impedance of the described first high impedance amplifier and the second high impedance amplifier is 10 of standard sample resistance impedance
6Doubly.
The described first high impedance amplifier and the second high impedance amplifier are high impedance amplifier able to programme.
Described device further comprises:
Gain adjustment unit links to each other with described high impedance amplifier, is used for adjusting the described first high impedance amplifier and the second high resistant Amplifier Gain when described numerical value through current signal after the analog-to-digital conversion and voltage signal is not within preset range.
Pretreatment unit is used for carrying out power-off protection when the numerical value that detects described current signal and voltage signal during greater than predetermined threshold value.
As seen through the above technical solutions, the present invention has following advantage and characteristics:
1, according to preset threshold value, adopt fft algorithm that current signal and voltage signal are carried out filtration treatment, effectively shielded DC component, high-frequency/low-frequency noise and other interfering signals, for the calculating of last bio-electrical impedance provides purified signal;
2, two inputs of a high impedance amplifier are linked to each other with low-impedance standard sample resistance on the series circuit that is arranged on the tested position of human body respectively, to obtain and to amplify current signal through described sample resistance; And with two inputs of another high impedance amplifier respectively with first test electrode and second test electrode of the both sides that are arranged on the tested position of human body, to obtain and to amplify voltage signal between described first test electrode and second test electrode; Because the impedance of described high impedance amplifier is 10
9More than ohm, and the impedance of the contact resistance that described sample resistance and test electrode produce is generally in ohm level, makes the current signal that described high impedance amplifier obtained and the actual current signal and the error between the voltage signal at voltage signal and the tested position of human body reduce greatly;
3, when the current value in current signal and the voltage signal and magnitude of voltage are not within preset range, can adjust Amplifier Gain automatically, guarantee the current value of each sampling and magnitude of voltage all in preset range, and then the sampling of different frequent points is carried out in optimum range all when guaranteeing the multifrequency point sampling.
Description of drawings
Fig. 1 is for eliminating the realization flow figure of interferential method in a kind of bio-electrical impedance measuring of the present invention;
Fig. 2 is for eliminating the flow chart of the embodiment one of interferential method in a kind of bio-electrical impedance measuring of the present invention;
Fig. 3 is for obtaining the structural representation of current signal and voltage signal in the embodiment of the invention one;
Fig. 4 is for eliminating the structured flowchart of the embodiment one of interferential device in a kind of bio-electrical impedance measuring of the present invention;
Fig. 5 is for eliminating the structured flowchart of the embodiment two of interferential device in a kind of bio-electrical impedance measuring of the present invention;
Fig. 6 is for eliminating the structured flowchart of the embodiment three of interferential device in a kind of bio-electrical impedance measuring of the present invention.
The specific embodiment
Core concept of the present invention is: obtain and amplify current signal on the sample resistance on the polyphone circuit at the voltage signal at the tested position of human body and the tested position of described human body; Current signal and voltage signal through analog-to-digital conversion are carried out fast fourier transform, extract the target current signal and the target voltage signal that satisfy the bio-electrical impedance design conditions.
The acquisition methods of described voltage signal and current signal comprises step: the standard sample resistance on the series circuit at the first high impedance amplifier and described tested position is arranged in parallel, obtaining the current signal on the series circuit of described tested position, the impedance of described high impedance amplifier be at least described sample resistance impedance 10
6Doubly; The second high impedance amplifier is linked to each other with second test electrode with first test electrode that is arranged on both sides, described tested position, to obtain the voltage signal at described tested position.
In order to make those skilled in the art person understand the present invention program better, the present invention is described in further detail below in conjunction with drawings and embodiments.
Please refer to Fig. 1,, may further comprise the steps for eliminating the realization flow figure of interferential method in a kind of bio-electrical impedance measuring of the present invention:
Step S101: obtain and amplify current signal on the sample resistance on the polyphone circuit at the voltage signal at the tested position of human body and the tested position of described human body.
Step S102: current signal and voltage signal through analog-to-digital conversion are carried out fast fourier transform, extract the target current signal and the target voltage signal that satisfy the bio-electrical impedance design conditions.
Please refer to Fig. 2,, may further comprise the steps for eliminating the flow chart of the embodiment one of interferential method in a kind of bio-electrical impedance measuring of the present invention:
Step S201: utilize the first high impedance amplifier to obtain and amplify current signal on the standard sample resistance on the series circuit that is arranged on the tested position of human body.
Step S202: utilize the second high impedance amplifier to obtain and amplify first test electrode of the both sides that are arranged on the tested position of human body and the voltage signal of second test electrode.
Please refer to Fig. 3, be the structural representation that obtains current signal and voltage signal of the embodiment of the invention one.
Among Fig. 3, signal source 01 is used to produce the sinusoidal wave swept frequency excitation signal that frequency is 1Hz-300KHz, and encourage the human test position at the described pumping signal the pure man of constant output body examination examination position; In this process, pumping signal arrives the 3rd test electrode 03 through the standard sample resistance; First test electrode 04, second test electrode 05 are arranged at the both sides at human test position; The input 071 of the first high impedance amplifier 07, input 072 link to each other with the two ends of described standard sample resistance respectively, and the input 081 of the second high impedance amplifier 08, input 082 link to each other with second test electrode 05 with first test electrode 04 respectively; Described first test electrode 04, second test electrode 05, the 3rd test electrode 03 and the power ground utmost point 06 contact with the human test position and produce contact resistance 031, contact resistance 041, contact resistance 051 and contact resistance 061.
The input impedance of the described first high impedance amplifier, the second high impedance amplifier is all 10
9More than ohm, and the impedance order of magnitude of standard sample resistance 02, contact resistance 041, contact resistance 051 and contact resistance 061 all is ohm level, is 10～10
3Ohm, and described standard sample resistance 02 is arranged on the polyphone circuit at human test position; Therefore, signal source 01 constant current carries the sine-wave current signal of coming all by all entering the human test position by contact resistance 031 behind the described standard sample resistance 02, there is electric current hardly on contact resistance 041 and the contact resistance 051, promptly produces pressure drop hardly; And then, the first high impedance amplifier 07 can accurately obtain current signal on the standard sample resistance 02 and that is to say the current value on the tested position 10 of people's body examination and it is amplified according to default amplification that the second high impedance amplifier 08 can accurately obtain the magnitude of voltage at the tested position 10 of described human body and it is amplified according to default amplification.
Step S203: the current value and the magnitude of voltage of the described processing and amplifying of described process are carried out analog-to-digital conversion, are digital signal by analog signal conversion.
With the current value of described each Frequency point through processing and amplifying with magnitude of voltage is parallel carries out analog-to-digital conversion, be digital signal by analog signal conversion.The frequency of described analog-to-digital conversion is 2 times more than or equal to the frequency of described Frequency point, is the current value and the magnitude of voltage of the process processing and amplifying of 10Hz for frequency, and the frequency of described analog-to-digital conversion is at least 20Hz.Form the multiple row signal thus, the corresponding Frequency point of every column signal.
Step S204: judge that whether the current value through analog-to-digital conversion is in the default scope (0.5 * range～0.8 * range), if not, enters step S208; Otherwise, enter step S205.
Step S205: adjust the described first high resistant amplifier magnification ratio gear.
As required the amplification (gain) of the described first high impedance amplifier is divided into 8 amplification gears such as 1,2,4,8,10,20,40,80, described range promptly is described amplification gear.
In order to ensure the current value that obtains at every turn all in default scope (0.5 * range～0.8 * range), described scope is to draw through test of many times according to the staff, be to carry out the best numerical range of analog-to-digital conversion, in the time of in current value is not in this scope, automatically adjust the gear of the amplification of the described first high impedance amplifier, make through the current value after its amplification to be in this scope.
Step S206: judge that whether the magnitude of voltage through analog-to-digital conversion is in the default scope (0.5 * range～0.8 * range), if not, enters step S208; Otherwise, enter step S207.
Step S207: adjust the described second high resistant amplifier magnification ratio gear.
As required the amplification (gain) of the described second high impedance amplifier is divided into 8 amplification gears such as 1,2,4,8,10,20,40,80, described range promptly is described amplification gear.
In order to ensure the magnitude of voltage that obtains at every turn all in default scope (0.5 * range～0.8 * range), described scope is to draw through test of many times according to the staff, be to carry out the best numerical range of analog-to-digital conversion, in the time of in magnitude of voltage is not in this scope, automatically adjust the gear of the amplification of the described second high impedance amplifier, make through the magnitude of voltage after its amplification to be in this scope.
Step S208: utilize the fast Flourier processing unit that the current value and the magnitude of voltage of a plurality of frequencies of process analog-to-digital conversion are handled.
In measurement in the past, the general virtual value that adopts detects voltage and current, inevitably the voltage and current of other frequencies is introduced virtual value, and in the voltage and current value that inevitably can produce other frequency ranges because of the hardware device in measuring process, because the current value of other frequencies of these generations and the doping of magnitude of voltage, finally offer the unitary signal of the impedance computation signal of more than 1Hz-300KHz frequency range certainly, must cause the inaccurate of final calculation result.
In addition, the method that adopts hardware filtering is also arranged, but hardware filtering is difficult to accomplish ideal bandpass filtering in the specific implementation process, and himself also inevitably can produces some noises signal generation interference.
So the present invention adopts the fast Flourier processing unit measured waveform to be divided into the multiple harmonic of standard with the mode of software, form harmonic spectrum, and be greater than or less than the signal of telecommunication of predetermined threshold value according to the electrical signal energy value that output frequency and default energy threshold filter other frequencies of deletion, the tested magnitude of voltage and the current value of real corresponding output frequency are extracted, improve the degree of purity of signal thus.
Current value and magnitude of voltage that for example corresponding output frequency is f0, in theory, the energy value of output frequency signal or range value energy value or the range value than the signal of other frequencies certainly are big, so can being set, a window function obtains the interior signal of [(f0-f010%)-(f0+f010%)] scope, and the signal of other frequencies is deleted, reach the effect of filtering.
The above the first high impedance amplifier and the second high impedance amplifier can be replaced by a high-impedance resistors and base amplifier, and the impedance of described high-impedance resistors can be 10 of the impedance of described standard sample resistance
7Doubly.
In order to prevent in measuring process, the phenomenon that is short-circuited causes electric current excessive and cause human body to receive that injury and each hardware device of participate in measuring are damaged, before described current signal and voltage signal are measured, its current value and magnitude of voltage are detected, when described current value or magnitude of voltage surpass predetermined threshold value, disconnecting circuit.
Described predetermined threshold value can be provided with according to the safe voltage of human body or the ability to bear standard of current standard and each hardware device.
Please refer to Fig. 4, for eliminating embodiment one structured flowchart of interferential device in a kind of bio-electrical impedance measuring of the present invention.
Eliminate interferential device in a kind of bio-electrical impedance measuring, comprising: standard sample resistance 100, first high impedance amplifier 200, second high impedance amplifier 300 and the fast Flourier processing unit 400.
In this binding signal source 01, the operation principle and the structure of AD conversion unit 500, computing controller 600 and first test electrode 04, second test electrode 05, the 3rd test electrode 03, earthing pole 06, contact resistance 041, contact resistance 051, contact resistance 031 and 061 pair of this device of contact resistance be elaborated.
The operation principle of this device is: the sinusoidal wave swept frequency excitation current signal that at signal source 01 constant current output frequency is 1Hz-300KHz encourages the tested position 10 of human body, and the input 211 of the first high impedance amplifier 200 and input 212 link to each other with the two ends of standard sample resistance 100 on the series circuit that is arranged on the tested position 10 of human body respectively; The input 311 of the second high impedance amplifier 300 links to each other with second test electrode 05 with first test electrode 04 that is arranged on 10 both sides, the tested position of human body respectively with input 312; Because the input impedance of the described first high impedance amplifier 200 and the second high impedance amplifier 300 is all 10
9More than ohm, and the described standard sample resistance 100 and first test electrode 04, second test electrode 05, the contact resistance 041 that the 3rd test electrode 03 and earthing pole 06 and the tested position of human body produce, contact resistance 042, the impedance order of magnitude of contact resistance 031 and contact resistance 061 all is ohm level, so from signal source 01 constant current output frequency is that the sinusoidal wave swept frequency excitation current signal of 1Hz-300KHz is almost all by described standard sample resistance 100, there is current signal hardly on contact resistance 041 and the contact resistance 051, so the described first high impedance amplifier 200 and the second high impedance amplifier 300 can obtain the purified current signal and the voltage signal of reflection human body tested position impedance 10, so-called pure, promptly be that interfering signal is less; Reduce the error that contact resistance that test electrode produces causes signal thus, improved the impedance measurement precision.The described first high impedance amplifier 200 and the second high impedance amplifier 300 offer AD conversion unit 500 by outfan 213 and outfan 313 respectively after described current signal and voltage signal are amplified it according to default amplification, current signal and voltage signal after described AD conversion unit 500 will be amplified are digital signal by analog signal conversion, and provide it to fast Flourier processing unit 400; The multiple harmonic that described fast Flourier processing unit 400 utilizes fft algorithm that the current signal and the voltage signal of described 1Hz-300KHz frequency range is divided into standard, form harmonic spectrum, and according to output frequency (1Hz-300KHz) and default energy threshold filter the signal of telecommunication of other frequencies of deletion or energy value greater than or the signal of telecommunication of little predetermined threshold value, the tested magnitude of voltage and the current value of real corresponding output frequency are extracted, provide it to computing controller 600 (current value and magnitude of voltage that for example corresponding output frequency is f0, in theory, the energy value of output frequency signal or range value energy value or the range value than the signal of other frequencies certainly are big, so can being set, a window function obtains the interior signal of [(f0-f010%)-(f0+f010%)] scope, and the signal of other frequencies is deleted, reach the effect of filtering), described computing controller 600 is calculated the electrical impedance at the tested position 10 of human body according to described magnitude of voltage and current value, and with its legend demonstration.
Please refer to Fig. 5, for eliminating the structured flowchart of the embodiment two of interferential device in a kind of bio-electrical impedance measuring of the present invention.
Because corresponding different frequency, the corresponding different frequency of the impedance at the tested position of human body must be different impedance, at the numerical value of low-frequency range and the numerical value of high band very big difference is arranged on scope, there is very big difference certainly in impedance when being 300KHz as the impedance when frequency is 1Hz and frequency, may hundreds of ohm when high band, then may reach ohms up to ten thousand in low-frequency range, so big mobility scale can cause interference to signal measurement, so the gain (amplification) of the described first high impedance amplifier 200 and the second high impedance amplifier 300 can be divided into 1,2,4,8,10,20,40,8 gain shift such as 80 grades, and the best scope of carrying out analog-to-digital conversion that draws according to test of many times, and empirical value (0.5 * range～0.8 * range) is set in view of the above, described range that is to say gain shift.By being provided with and the modulus dress changes the gain adjusting unit 700 that unit 400, the first high impedance amplifier 200 and the second high impedance amplifier 300 link to each other, when described gain adjusting unit 700 detects when the current value of a certain frequency of analog-to-digital conversion or magnitude of voltage are not in predetermined threshold value, adjust the gain of the described first high impedance amplifier 200 and the second high impedance amplifier 300 current value or magnitude of voltage are carried out processing and amplifying again, and carry out analog-to-digital conversion again by analog-to-digital conversion unit 400.
As shown in Figure 6, for eliminating the structured flowchart of the embodiment three of interferential device in a kind of bio-electrical impedance measuring of the present invention.
For fear of when being short-circuited; human body is received the generation of the situation that injury and each hardware that participates in measuring are damaged; pretreatment unit 800 can further be set in device; be used for before measuring, current value or the magnitude of voltage that obtains being detected; when detecting described current value or magnitude of voltage above predetermined threshold value; automatically outage realizes the self-protection function.
The first high impedance amplifier described in the above embodiment and the second high impedance amplifier can each be replaced by base amplifier of a high-impedance resistors series connection, and the resistance value of described high-impedance resistors is at least 10 of described standard sample resistance resistance value
6Doubly.
More than disclosed only be preferred implementation of the present invention; but the present invention is not limited thereto; any those skilled in the art can think do not have a creationary variation, and, all should drop in protection scope of the present invention not breaking away from some improvements and modifications of being done under the principle of the invention prerequisite.
Claims (9)
1. eliminate interferential method in a bio-electrical impedance measuring, it is characterized in that described method comprises step:
Obtain and amplify current signal on the sample resistance on the polyphone circuit at the voltage signal at the tested position of human body and the tested position of described human body;
Current signal and voltage signal through analog-to-digital conversion are carried out fast fourier transform, described current signal and voltage signal are generated harmonic spectrum, according to the threshold value that is provided with by exciting signal frequency scope and signal energy spectrum described current signal and voltage signal are carried out filtering screening, extract the target current signal and the target voltage signal that satisfy the bio-electrical impedance design conditions.
2. eliminate interferential method in the bio-electrical impedance measuring as claimed in claim 1, it is characterized in that, obtain and the step of amplifying the current signal on the sample resistance on the polyphone circuit at the voltage signal at the tested position of human body and the tested position of described human body comprises:
Sample resistance on the series circuit at the first high impedance amplifier and described tested position is arranged in parallel, obtaining the current signal on the series circuit of described tested position, the impedance of described high impedance amplifier be at least described sample resistance impedance 10
6Doubly;
The second high impedance amplifier is linked to each other with second test electrode with first test electrode that is arranged on both sides, described tested position, to obtain the voltage signal at described tested position.
3. eliminate interferential method in the bio-electrical impedance measuring as claimed in claim 2, it is characterized in that, to before carrying out fast fourier transform through the current signal of analog-to-digital conversion and voltage signal, further comprise: when described numerical value through current signal after the analog-to-digital conversion and voltage signal is not within preset range, adjust the described first high impedance amplifier and the second high resistant Amplifier Gain.
4. eliminate interferential method in the bio-electrical impedance measuring as claimed in claim 1, it is characterized in that, before obtaining and amplifying current signal on the sample resistance on the polyphone circuit at the voltage signal at the tested position of human body and the tested position of described human body, further comprise: described current signal and voltage signal are carried out the pressure-limit current-limit pretreatment.
5. eliminate interferential method in the bio-electrical impedance measuring as claimed in claim 4, it is characterized in that the pretreated method of described pressure-limit current-limit is specially:
Detect the current value and the magnitude of voltage of described current signal and voltage signal respectively, when detecting described current value or magnitude of voltage and exceed predetermined threshold value, disconnect and connecting.
6. a biologic resistance is eliminated interferential device in measuring, and it is characterized in that described device comprises:
High impedance amplifier, the sample resistance current signal on the polyphone circuit that is used to obtain the voltage signal at the tested position of human body and be arranged on the tested position of human body;
The fast Flourier processing unit, link to each other with described high impedance amplifier, utilize fast fourier algorithm that described current signal and voltage signal are handled, described current signal and voltage signal are generated harmonic spectrum, according to the threshold value that is provided with by exciting signal frequency scope and signal energy spectrum described current signal and voltage signal are carried out filtering screening, extract the target current signal and the target voltage signal that satisfy the bio-electrical impedance design conditions.
7. eliminate interferential device in the bio-electrical impedance measuring as claimed in claim 6, it is characterized in that described high impedance amplifier comprises:
The first high impedance amplifier comprises two inputs and an outfan, and described two inputs link to each other with the two ends of described sample resistance respectively, is used to obtain and amplify the current signal of the described sample resistance of process;
The second high impedance amplifier, comprise two inputs and an outfan, described two inputs link to each other with second test electrode with first test electrode that is arranged on both sides, the tested position of human body respectively, are used to obtain and amplify the voltage signal of both sides, the tested position of described human body.
8. eliminate interferential device during biologic resistance as claimed in claim 7 is measured, it is characterized in that: the input impedance of the described first high impedance amplifier and the second high impedance amplifier is 10 of sample resistance impedance
6Doubly.
9. eliminate interferential device during biologic resistance as claimed in claim 7 is measured, it is characterized in that, further comprise:
Gain adjustment unit links to each other with described high impedance amplifier, is used for adjusting the described first high impedance amplifier and the second high resistant Amplifier Gain when when the numerical value of current signal after the analog-to-digital conversion and voltage signal is not within preset range.
Pretreatment unit is used for carrying out power-off protection when the numerical value that detects described current signal and voltage signal during greater than predetermined threshold value.
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| CN101871974B (en) * | 2010-06-18 | 2013-01-09 | 华南理工大学 | Impedance spectroscopy measurement method |
| CN102955080A (en) * | 2011-08-16 | 2013-03-06 | 重庆融海超声医学工程研究中心有限公司 | Portable measuring instrument and measuring method for electrical parameters |
| US20150196224A1 (en) * | 2014-01-16 | 2015-07-16 | Dermal Therapy (Barbados) Inc. | Implantable Sensor and Method for Such Sensor |
| CN106597068A (en) * | 2015-10-19 | 2017-04-26 | 沈阳新松机器人自动化股份有限公司 | Current sampling circuit and sampling method |
| CN106137192A (en) * | 2016-07-27 | 2016-11-23 | 北京四海华辰科技有限公司 | A kind of body impedance measurement devices and bioelectrical impedance analysis instrument thereof |
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| US5454377A (en) * | 1993-10-08 | 1995-10-03 | The Ohio State University | Method for measuring the myocardial electrical impedance spectrum |
| CN1286400A (en) * | 1999-08-26 | 2001-03-07 | 株式会社百利达 | Apparatus for measuring biologic electric impedance of living body |
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