Disclosure of Invention
Based on the above, it is necessary to provide an electrical stimulation device for the lingual nerve, aiming at the technical problem that the traditional lingual nerve stimulator has a complex structure.
An electrical stimulation device for the lingual nerve comprising: the device comprises an electrode array, a wireless communication module, a controller, a pulse generation circuit, a first dielectric substrate, a second dielectric substrate and a third dielectric substrate; the first medium substrate, the second medium substrate and the third medium substrate are identical in size, and all have specific shapes;
the controller is connected with the electrode array through the pulse generating circuit; the controller is connected with the wireless communication module; the electrode array is integrated on the first medium substrate, the controller and the pulse generating circuit are integrated on the second medium substrate, and the wireless communication module is integrated on the third medium substrate; the first dielectric substrate, the second dielectric substrate and the third dielectric substrate are sequentially attached.
In one embodiment, the controller receives a slope parameter sent by the terminal through the wireless communication module, and adjusts a pulse parameter of the pulse generating circuit according to the slope parameter; the slope parameter characterizes the duration change trend of the first user in a specific state in each statistic period of the monitoring period; the monitoring period is a period during which the lingual nerve of the first user receives electrical stimulation.
As one embodiment, the controller adjusts the pulse parameter down when it is identified that the slope parameter is negative and the absolute value of the slope parameter is greater than the first adjustment threshold; and when the slope parameter is identified as positive, and the absolute value of the slope parameter is larger than the second adjustment threshold value, the pulse parameter is adjusted.
As one embodiment, the pulse parameters include pulse amplitude and pulse duty cycle;
the controller reduces the pulse amplitude by a first set proportion; and/or, decreasing the pulse duty cycle by a second set proportion to decrease the pulse parameter;
the controller increases the pulse amplitude by a first set proportion; and/or, the pulse duty ratio is adjusted to be larger by a second set proportion so as to adjust the pulse parameter.
As one embodiment, the controller maintains the pulse parameter unchanged upon identifying an opposite number of the slope parameter being less than or equal to the second adjustment threshold and greater than or equal to the first adjustment threshold.
In one embodiment, the terminal obtains the statistical duration of the first user in the specific state in a plurality of statistical periods, and determines the slope parameter according to the statistical duration of each statistical period. The monitoring period includes a plurality of statistical periods.
In one embodiment, the electrical stimulation device for lingual nerve further comprises a power supply module, wherein the power supply module is respectively connected with the wireless communication module, the controller and the pulse generation circuit; the power supply module is arranged on the second dielectric substrate.
As an embodiment, the power supply module is a rechargeable battery;
the electric stimulation device of the lingual nerve also comprises a charging coil; the charging coil is connected with the rechargeable battery; the charging coil is disposed on the third dielectric substrate.
In one embodiment, the above-mentioned electric stimulation device for lingual nerve further comprises a remote control; the remote controller is communicated with the controller through a wireless communication module;
the remote controller is used for reading a control instruction of a user and sending the control instruction to the controller through the wireless communication module; the controller controls the pulse generating circuit to send out pulse signals according to the control instruction.
In one embodiment, the individual electrodes of the electrode array are uniformly disposed on the first dielectric substrate.
According to the electric stimulation device for the lingual nerve, the electrode array can be integrally arranged on the first medium substrate, the controller and the pulse generation circuit are integrally arranged on the second medium substrate, and the wireless communication module is integrally arranged on the third medium substrate, so that the structure of the electric stimulation device formed by sequentially attaching the first medium substrate, the second medium substrate and the third medium substrate is effectively simplified, the electric stimulation device can be directly attached to the lingual head of a corresponding user, the controller in the electric stimulation device can receive a control instruction of external equipment through the wireless communication module to control the pulse generation circuit to generate a pulse signal, and therefore the electrode array can send a stimulation action to stimulate the lingual nerve of the corresponding user, and the comfort level of the corresponding user in the process of receiving lingual nerve stimulation can be improved.
Detailed Description
The present invention will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present invention more apparent. It should be understood that the detailed description is presented by way of example only and is not intended to limit the scope of the invention.
It should be noted that, the term "first\second\third" related to the embodiment of the present invention is merely to distinguish similar objects, and does not represent a specific order for the objects, it is to be understood that "first\second\third" may interchange a specific order or sequence where allowed. It is to be understood that the "first\second\third" distinguishing aspects may be interchanged where appropriate to enable embodiments of the invention described herein to be implemented in sequences other than those illustrated or described.
The terms "comprising" and "having" and any variations thereof, are intended to cover a non-exclusive inclusion. For example, a process, method, system, article, or apparatus that comprises a list of steps or modules is not limited to only those steps or modules but may include other steps or modules not expressly listed or inherent to such process, method, article, or apparatus.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the present application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.
References herein to "a plurality" means two or more. "and/or", describes an association relationship of an association object, and indicates that there may be three relationships, for example, a and/or B, and may indicate: a exists alone, A and B exist together, and B exists alone. The character "/" generally indicates that the context-dependent object is an "or" relationship.
Referring to fig. 3, fig. 3 is a schematic structural diagram of an electrical stimulation device for a lingual nerve according to an embodiment, where the electrical stimulation device for a lingual nerve includes: an electrode array 11, a wireless communication module 13, a controller 15, a pulse generation circuit 17, a first dielectric substrate (not shown in fig. 3), a second dielectric substrate (not shown in fig. 3), and a third dielectric substrate (not shown in fig. 3); the first medium substrate, the second medium substrate and the third medium substrate are identical in size, and all have specific shapes;
the controller 15 is connected with the electrode array 11 through the pulse generating circuit 17; the controller 15 is connected with the wireless communication module 13; the electrode array 11 is integrally arranged on a first medium substrate, the controller 15 and the pulse generating circuit 17 are integrally arranged on a second medium substrate, and the wireless communication module 13 is integrally arranged on a third medium substrate; the first dielectric substrate, the second dielectric substrate and the third dielectric substrate are sequentially attached.
The first, second and third dielectric substrates may be printed circuit boards (PCB circuit boards), respectively. Specifically, after the first dielectric substrate, the second dielectric substrate and the third dielectric substrate are sequentially attached to obtain the device integrated structure, the parts except the electrodes on the device integrated structure, namely the parts except the electrodes on the surfaces of the first dielectric substrate, the second dielectric substrate and the third dielectric substrate after being attached are coated by using insulating materials such as silica gel or plastic films, so that the electrodes which send out the stimulating action are exposed on the basis of ensuring the safety and the comfort level in the use process of a user, and the electrodes are in direct contact with the tongue, thereby providing more effective electric stimulation for the tongue nerves.
The specific shape may be a shape similar to the tongue, such as an oval shape or a pointed circular shape. The first, second and third dielectric substrates may be sized according to the size of the human tongue, e.g., slightly smaller than the tongue size, and the first, second and third dielectric substrates may be sized identically. The first dielectric substrate, the second dielectric substrate and the third dielectric substrate are sequentially attached, the obtained electric stimulation device is a flat sheet with a specific shape, and when the electric stimulation device is used, one surface (the surface where the first dielectric substrate is positioned) provided with the electrode array 11 can be attached to the tongue, so that the electrode array 11 of the electric stimulation device can send out a stimulation action to electrically stimulate the tongue nerve.
The wireless communication module 13 may include a bluetooth communication module, a wifi module, or the like, and may be capable of receiving and transmitting control data and control instructions. Specifically, the controller 15 may receive a control instruction sent by another intelligent terminal through the wireless communication module 13, and control the pulse generating circuit 17 to generate a pulse signal according to the control instruction, and transmit the pulse signal to the electrode array 11, so that the electrode array 11 sends out a stimulating action.
According to the electric stimulation device for the lingual nerve, the electrode array 11 can be integrally arranged on the first medium substrate, the controller 15 and the pulse generation circuit 17 are integrally arranged on the second medium substrate, and the wireless communication module 13 is integrally arranged on the third medium substrate, so that the structure of the electric stimulation device formed by sequentially attaching the first medium substrate, the second medium substrate and the third medium substrate is effectively simplified, the electric stimulation device can be directly attached to the lingual nerve of a corresponding user, the controller 15 in the electric stimulation device can receive a control instruction of external equipment through the wireless communication module 13 to control the pulse generation circuit 17 to generate a pulse signal, and therefore the electrode array 11 can send out a stimulation action to stimulate the lingual nerve of the corresponding user, and the comfort level of the corresponding user in the process of receiving lingual nerve stimulation can be improved.
In one embodiment, the schematic diagrams of the two sides of the above-mentioned electrical stimulation device for lingual nerve may be as shown in fig. 4, where each electrode of the electrode array may be uniformly distributed on one side (the side corresponding to the first dielectric substrate) of the electrical stimulation device, and the other side (the side corresponding to the third dielectric substrate) of the electrical stimulation device may be provided with components such as a wireless communication module. In a specific working process, the controller can receive a control instruction sent by control equipment such as a remote controller or a control end through the wireless communication module, and control the pulse generation circuit to generate a pulse signal according to the control instruction, and the pulse signal is transmitted to the electrode array, so that the electrode array sends out a stimulating action to stimulate the lingual nerve of the first user. The first user is a user who needs to receive the tongue nerve stimulation.
In one embodiment, the controller receives a slope parameter sent by the terminal through the wireless communication module, and adjusts a pulse parameter of the pulse generating circuit according to the slope parameter; the slope parameter characterizes the duration change trend of the first user in a specific state in each statistic period of the monitoring period; the monitoring period is a period during which the lingual nerve of the first user receives electrical stimulation.
The first user may be a user who needs to receive electrical stimulation of the tongue nerve, such as a PD patient. The particular state may be an OFF state or the like that characterizes the state in which the first user's athletic symptom onset is located. The OFF state is the motor symptom onset state of the PD patient. Typically, when a first user gives symptoms of movement that can be indicative of a particular state, such as tremor and/or bradykinesia, the first user may be determined to be in the particular state. The terminal can acquire state parameters such as the time length of the first user in a specific state in each statistic period of the monitoring period through the related state parameter acquisition device, and obtain slope parameters representing the time length change trend of the first user in the specific state in each statistic period of the monitoring period.
The terminal is an intelligent device for collecting the statistical time length of the first user in a specific state in each statistical time period and determining the slope parameter representing the time length change trend according to the statistical time length. The monitoring period includes a plurality of statistical periods. The monitoring period may be set according to a time length feature of the first user receiving the electrical stimulation, for example, the monitoring period may be set to a period of one week or one month. The statistical time period can be set according to the total duration characteristic of the monitoring time period, for example, if the monitoring time period is a week, each statistical time period included in the monitoring time period can be each day in the week, namely, the 1 st day is the 1 st statistical time period, the 2 nd day is the 2 nd statistical time period, … …, and the 7 th day is the 7 th statistical time period; if the monitoring period is one month, each statistical period included in the monitoring period may be each week in the month, that is, 1 st week is 1 st statistical period, 2 nd week is 2 nd statistical period, … …, and 4 th week is 4 th statistical period. Specifically, in the monitoring period, two adjacent statistical periods are continuous in time, that is, the initial time of each statistical period is continuous with the end time of the previous statistical period of the corresponding statistical period, which is beneficial to uninterrupted monitoring of the specific state of the first user and ensuring the validity of the acquired statistical period.
As an example, the above-mentioned electrical stimulation device for lingual nerve may be applied in an application environment as shown in fig. 5. In the application environment, the terminal may be an intelligent Mobile Device (MD), one side of the MD is a Device for collecting a state parameter of the first user, and the other side of the MD is an electrical stimulation Device of the lingual nerve. The state parameter acquisition device can be worn on the first user to acquire various state parameters generated by the first user in a monitoring period; the electrical stimulation device is placed on the tongue of the first user to deliver electrical stimulation to the lingual nerve of the first user. The MD is respectively in communication connection with the state parameter acquisition device and the electric stimulation device. The microcontroller of the state parameter acquisition device is communicated with MD (mobile device) through a communication module, components such as a 3-D acceleration sensor, a heart rate sensor, a microphone and the like in the state parameter acquisition device can be integrally arranged on a bracelet worn by a first user, and a pressure sensor in the state parameter acquisition device can be arranged on a foot pad on the sole of the first user; the 3-D acceleration sensor, the heart rate sensor, the microphone and/or the pressure sensor can acquire the state parameters of the first user in a specific state, the state parameters are sent to the analog-to-digital converter to be subjected to analog-to-digital conversion to be digital signals and then sent to the microcontroller, and the microcontroller sends the state parameters to the MD through the communication module, so that the MD can determine the needed slope parameters according to the state parameters. The MD sends the slope parameter to a microcontroller (controller) of the electric stimulation device through a communication module (wireless communication module) of the electric stimulation device, so that the microcontroller controls a constant current source pulse generating circuit (pulse generating circuit) to generate a pulse signal according to the slope parameter, and the electrode array is controlled to send out electric stimulation to electrically stimulate the lingual nerve of the first user. The MD may be held by a second user, where the second user may include a first user and a doctor of the first user, etc. needs to learn the state of the first user, and the first user may be a PD patient, etc. needs to receive electrical stimulation of the lingual nerve. MD may be, but is not limited to, various notebook computers, smartphones, tablet computers, and portable wearable devices.
As one embodiment, the controller adjusts the pulse parameter down when it is identified that the slope parameter is negative (less than 0) and the absolute value of the slope parameter is greater than the first adjustment threshold; when the slope parameter is identified as positive (a value greater than 0) and the absolute value of the slope parameter is greater than the second adjustment threshold, the pulse parameter is turned up.
The pulse parameters may include parameters such as pulse amplitude and/or pulse duty cycle. The controller may adjust the pulse parameters down by adjusting the pulse amplitude and/or the pulse duty cycle and adjust the pulse parameters up by adjusting the pulse amplitude and/or the pulse duty cycle.
The first adjustment threshold and the second adjustment threshold are positive values respectively. The first adjustment threshold and the second adjustment threshold may be set according to a duration feature of the monitoring period and a specific state of the first user, for example, if the monitoring period is 4 weeks, the first adjustment threshold may be set to 6 hours, and the second adjustment threshold may be set to 4 hours.
In this embodiment, the controller may obtain, from the terminal, a slope parameter corresponding to a specific state of the first user in the monitoring period, adaptively adjust an electrical stimulation device that electrically stimulates the tongue nerve of the first user according to the slope parameter that characterizes a trend of a change in a duration of the first user in the specific state in each statistics period of the monitoring period, so that a stimulation behavior sent by the electrical stimulation device of the tongue nerve may be adjusted according to a specific state characteristic of the first user in the monitoring period, so that the corresponding stimulation behavior is more targeted, a pulse parameter adjustment process of the electrical stimulation device may be simplified, and instantaneity of adjusting pulse parameters may be improved.
As one embodiment, the pulse parameters include pulse amplitude and pulse duty cycle;
the controller reduces the pulse amplitude by a first set proportion; and/or, decreasing the pulse duty cycle by a second set proportion to decrease the pulse parameter;
the controller increases the pulse amplitude by a first set proportion; and/or, the pulse duty ratio is adjusted to be larger by a second set proportion so as to adjust the pulse parameter.
The first setting proportion and the second setting proportion can be set according to the configuration characteristics of the electric stimulation device of the lingual nerve, and the values of the first setting proportion and the second setting proportion can be the same or different, for example, if the pulse amplitude of the electric stimulation device is reduced by the first setting proportion or the pulse duty ratio of the electric stimulation device is reduced by the second setting proportion to realize the reduction of corresponding pulse parameters, the first setting proportion and the second setting proportion can be set to be 5% respectively.
As one embodiment, the controller maintains the pulse parameter unchanged upon identifying an opposite number of the slope parameter being less than or equal to the second adjustment threshold and greater than or equal to the first adjustment threshold.
If the slope parameter is smaller than or equal to the second adjustment threshold value and is larger than or equal to the opposite number of the first adjustment threshold value, the current pulse parameter of the electric stimulation device is the pulse parameter required by the tongue nerve of the first user to receive the corresponding electric stimulation, and the current pulse parameter can be kept unchanged without relevant adjustment.
As an example, if the first setting ratio and the second setting ratio are set to 5% respectively, b OFF Representing a slope parameter, A1 representing a first adjustment threshold, A2 representing a second adjustment threshold, and the symbol "||" representing an absolute value; the above-mentioned pulse parameter adjustment process may be shown in fig. 6, and includes:
if b OFF < 0 and |b OFF The pulse amplitude is reduced by 5% or the pulse duty ratio is reduced by 5% by I > A1;
if b OFF > 0 and |b OFF The pulse amplitude is increased by 5% or the pulse duty ratio is increased by 5% by I > A2;
if none of the above conditions is satisfied (i.e., b OFF < 0 and |b OFF I > A1 and b OFF > 0 and |b OFF Both of i > A2 are not true), keeping the pulse parameters unchanged.
In one embodiment, the terminal obtains the statistical duration of the first user in a specific state in a plurality of statistical periods, and determines the slope parameter according to the statistical duration of each statistical period. The monitoring period includes a plurality of statistical periods.
Specifically, the unit duration of each time the first user is in a specific state in each statistics period can be obtained, and the sum of the unit durations of the statistics periods is determined as the statistics duration of the first user in the corresponding statistics period.
According to the embodiment, a curve can be drawn according to the statistical duration of each statistical period, so that the slope parameter corresponding to the specific state of the first user in the monitoring period can be determined according to the curve. Specifically, the trend parameter corresponding to the curve with the ascending trend is greater than 0, the trend parameter corresponding to the curve with the descending trend is less than 0, and the trend parameter corresponding to the leveled curve is equal to 0.
As an example, if the specific state is an OFF state, the monitoring period is one month, each statistical period is each week in one month, and a curve drawn according to the statistical duration of each statistical period may be shown with reference to fig. 7.
As an embodiment, the process of determining the slope parameter by the terminal according to the statistical duration of each statistical period may include:
substituting the statistical time length and the time sequence number of each statistical time period into a slope determination formula to calculate a slope parameter of the first user in a specific state in the monitoring time period; the slope determination formula includes:
wherein b represents a slope parameter, X i A period number indicating an ith statistical period, Y i The statistical duration of the ith statistical period is represented, and N represents the number of the statistical periods included in the monitoring period; such as coordinates (X) i ,Y i ) Representing a statistical period X i Is Y i 。
The present embodiment can make a more accurate determination of the slope parameter.
In one embodiment, referring to fig. 8, the above-mentioned electrical stimulation device for lingual nerve further includes a power supply module 18, where the power supply module 18 is connected to the wireless communication module 13, the controller 15 and the pulse generation circuit 17, respectively; the power module 18 is disposed on the second dielectric substrate.
The power supply module 18 supplies power to the wireless communication module 13, the controller 15 and the pulse generation circuit 17 respectively, so that smooth work of the corresponding tongue nerve electric stimulation device is ensured.
As an embodiment, the power supply module is a rechargeable battery;
the electric stimulation device of the lingual nerve also comprises a charging coil; the charging coil is connected with the rechargeable battery; the charging coil is disposed on the third dielectric substrate.
The power supply module is a rechargeable battery, and the rechargeable battery is connected with the corresponding charging coil, so that the electric stimulation device of the lingual nerve can be directly placed on the charging base corresponding to the charging coil for charging, and the convenience of the electric stimulation device of the lingual nerve in the reuse process is further ensured.
In one embodiment, the above-mentioned electric stimulation device for lingual nerve further comprises a remote control; the remote controller is communicated with the controller through a wireless communication module;
the remote controller is used for reading a control instruction of a user and sending the control instruction to the controller through the wireless communication module; the controller controls the pulse generating circuit to send out pulse signals according to the control instruction.
The control command may include a pulse generation command, and the controller may control the pulse generation circuit to emit a pulse signal after receiving the control command. The control command may further include a pulse parameter, so that the controller controls the pulse generating circuit to send out a corresponding pulse signal according to the pulse parameter.
According to the embodiment, the pulse parameters can be controlled by inputting the control instruction through the remote controller, so that the convenience of controlling the electric stimulation device of the corresponding lingual nerve is further improved.
In one embodiment, the individual electrodes of the electrode array are uniformly disposed on the first dielectric substrate.
Specifically, a plurality of rows of electrodes can be arranged on the first dielectric substrate, the distances between every two adjacent rows of electrodes are equal, and in each row of electrodes, the intervals between every two adjacent electrodes are equal, so that each electrode of the electrode array is uniformly arranged on the first dielectric substrate, the uniformity of the stimulation action sent by the lingual nerve is ensured, and the corresponding stimulation effect is further ensured.
In one embodiment, a schematic diagram of each dielectric substrate (first, second, and third dielectric substrates) may be shown with reference to fig. 9, in which fig. 9, the electrode layer may represent the first dielectric substrate on which the electrode array may be disposed; the electronic component layer may represent a second dielectric substrate on which related integrated circuits such as a rechargeable battery, a controller, and a pulse generating circuit may be disposed; the communication and charging coil layer may represent a third dielectric substrate on which components such as a charging coil, a wireless communication module, and a communication antenna may be disposed. And sequentially attaching the first medium substrate, the second medium substrate and the third medium substrate to obtain the electric stimulation device for the lingual nerve. In the use process of the tongue nerve electric stimulation device, one surface where the electrode array is located can be attached to the tongue head of the first user so as to perform corresponding electric stimulation on the tongue of the first user.
The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The above examples illustrate only a few embodiments of the invention, which are described in detail and are not to be construed as limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.