CN109663216A - Optical dynamic therapy light-source system and optical dynamic therapy irradiator - Google Patents
Optical dynamic therapy light-source system and optical dynamic therapy irradiator Download PDFInfo
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- CN109663216A CN109663216A CN201811568421.9A CN201811568421A CN109663216A CN 109663216 A CN109663216 A CN 109663216A CN 201811568421 A CN201811568421 A CN 201811568421A CN 109663216 A CN109663216 A CN 109663216A
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- optical lens
- lens array
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0664—Details
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Abstract
The present invention provides a kind of optical dynamic therapy light-source system and optical dynamic therapy irradiator, the optical dynamic therapy includes successively multispectral irradiation mould group, the first optical lens array and the second optical lens array disposed in parallel with light-source system, multispectral irradiation mould group includes wiring board and at least one multispectral Sony ericsson mobile comm ab, and each lenslet on the second optical lens array is overlapped with the center of each lenslet on the first optical lens array and each side corresponds；Multispectral irradiation mould group is 3~5mm at a distance from the first optical lens array, and the first optical lens array is 0.85~1.15 times of the focal length of lenslet at a distance from the second optical lens array.The present invention can provide enough illumination power densities for optical dynamic therapy, it can also be achieved the Uniform Irradiation to patient's treatment zone, illumination power density distribution curved surface height of the light beam of each different wave length in patient's treatment zone is similar, can effectively enhance therapeutic effect.
Description
Technical field
The present invention relates to optical dynamic therapy technical fields, and in particular to a kind of optical dynamic therapy light-source system and light power
Treat irradiator.
Background technique
Optical dynamic therapy with light source be optical dynamic therapy core and crucial, the wavelength of light source, illumination power density, illumination
It is dynamic that the technical indicators such as the illumination power density distribution curved surface of the uniformity, different wavelengths of light in effective irradiation area directly affect light
The effect of power treatment.In the prior art, multispectral Sony ericsson mobile comm ab is generallyd use as optical dynamic therapy light source.
However, the luminous flux of single led chip is limited at present, light irradiation power is wanted far from optical dynamic therapy is met
It asks.To realize high-power illumination output, usually several LED chips are arranged in array in the prior art after constituting area source
As optical dynamic therapy light source.Since the typical emission pattern of LED chip is to dissipate, in the light source be made of LED chip
It will form light interference phenomenon since the light that single led chip issues can generate repeatedly crosslinking, can finally make to reach patient in this way
Treatment region light energy reduce, uniform illumination degree it is not high, formed treatment region surface different location luminous intensity size it is poor
It is different, to affect optical dynamic therapy effect.
In addition, optimal spectrum requirement required when to adapt to different photosensitizing agents, it is usually necessary to use light for clinical application
The multispectral combination therapy mode of power.It is arranged in array in the LED chip of multiple and different wavelength and constitutes optical dynamic therapy light source
When, since the light angle of scattering that the LED chip of each different wave length issues is different, so that different wave length light is in effective irradiated region
Illumination power density distribution curve form in domain is widely different, to cause using the LED chip of multiple and different wavelength as light
The multispectral combination therapy mode of the light power in source it is ineffective.
Summary of the invention
The embodiment of the present invention provides a kind of optical dynamic therapy light-source system and optical dynamic therapy irradiator, existing to solve
For the efficiency of light energy utilization to be low, uneven illumination is even, treatment region surface different wave length existing for the light source of optical dynamic therapy in technology
Illumination power density distribution curve form differ greatly etc. a series of influence optical dynamic therapy effects the problem of.
In a first aspect, the embodiment of the present invention provides a kind of optical dynamic therapy light-source system, including successively disposed in parallel
Multispectral irradiation mould group, the first optical lens array and the second optical lens array；
The multispectral irradiation mould group includes wiring board and at least one can generate the parallel standard of more different wave lengths
Straight and the uniform light pencil of hot spot multispectral Sony ericsson mobile comm ab, each multispectral orthogonal thereto array row of Sony ericsson mobile comm ab
Cloth is on the wiring board；
The side direction of refractive lenslet on first optical lens array with multiple orthogonal thereto array arrangements
The multispectral irradiation mould group, with the refractive lenslet of multiple orthogonal thereto array arrangements on second optical lens array
Each lenslet of the side in the multispectral irradiation mould group, second optical lens array and first optical lens
The center of each lenslet on lens array is overlapped and each side corresponds；The multispectral irradiation mould group and first optical lens
The distance of lens array is 3~5mm, and first optical lens array is described small at a distance from second optical lens array
0.85~1.15 times of the focal length of lens.
As the preferred embodiment of first aspect present invention, the multispectral Sony ericsson mobile comm ab includes package substrate, described
It is provided with reflector on the loading end of package substrate, at least two different wave lengths are provided in the accommodation space of the reflector
Solid-state light emitting element；The package substrate two sides are provided at least two pairs of electrodes, the electrode and the solid-state light emitting element
Positive and negative anodes are connected；
It is also closed off at the light-emitting window of the reflector and is provided with microlens array, the microlens array and the encapsulation base
Plate is parallel, and the side of the refractive hemispherical microlenses on the microlens array with multiple orthogonal thereto array arrangements is backwards
The solid-state light emitting element.
As the preferred embodiment of first aspect present invention, the solid-state light emitting element is included in 620~630nm wave-length coverage
The interior red LED chip with peak wavelength, in 520~530nm wave-length coverage with peak wavelength green LED chip with
And with the blue-light LED chip of peak wavelength in 460~470nm wave-length coverage.
As the preferred embodiment of first aspect present invention, the red LED chip, the green LED chip and the indigo plant
The arrangement in equilateral triangle of light LED chip, the red LED chip, the green LED chip and the blue-light LED chip phase
The distance between mutual is 0.1~0.2mm.
As the preferred embodiment of first aspect present invention, the radius of the lenticule is 0.05~0.25mm, described micro-
The focal length of mirror is 0.8mm, and the distance between rounded bottom surface of the adjacent lenticule is 0mm.
As the preferred embodiment of first aspect present invention, the radius of the lenticule is 0.15mm.
As the preferred embodiment of first aspect present invention, the height of the reflector is identical as the focal length of the lenticule.
As the preferred embodiment of first aspect present invention, first optical lens array and the second optical lens battle array
Lenslet close-packed arrays on column, the lenslet are regular hexagon or rectangle.
As the preferred embodiment of first aspect present invention, first optical lens array and the second optical lens battle array
The distance of column is identical as the focal length of the lenslet.
Second aspect, the embodiment of the present invention provide a kind of optical dynamic therapy irradiator, including drive end bearing bracket, rear end cap and set
Set the optical dynamic therapy light source as described in any one of above-mentioned first aspect between the drive end bearing bracket and the rear end cap
System.
Optical dynamic therapy light-source system provided in an embodiment of the present invention, it is multiple orthogonal thereto using integrating in the circuit board
The structure of the multispectral Sony ericsson mobile comm ab of array arrangement, since the multispectral Sony ericsson mobile comm ab is by going out light in reflector
Closing setting microlens array can produce more parallel collimations and the uniform light pencil of hot spot at mouthful, so as to be optical dynamic therapy
Enough illumination power densities are provided；The parallel collimation and hot spot for the different wave length that multiple multispectral Sony ericsson mobile comm abs generate are equal
Even light beam successively passes through two optical lens arrays and exports the Uniform Irradiation, it can be achieved that patient's treatment zone, each difference
Illumination power density distribution curved surface height of the light beam of wavelength in patient's treatment zone is similar, can effectively enhance treatment effect
Fruit.
Further, using the optical dynamic therapy irradiator of the optical dynamic therapy light-source system, installation is simple, square
Just, and optical dynamic therapy effect is preferable.
Detailed description of the invention
To describe the technical solutions in the embodiments of the present invention more clearly, make required in being described below to embodiment
Attached drawing is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the invention, for
For those of ordinary skill in the art, without creative efforts, it can also be obtained according to these attached drawings other
Attached drawing.
Fig. 1 is a kind of structural schematic diagram of optical dynamic therapy light-source system provided in an embodiment of the present invention；
Fig. 2 is the structure of multispectral irradiation mould group in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention
Schematic diagram；
Fig. 3 is that multispectral irradiation mould group uses in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention
The structural schematic diagram of multispectral Sony ericsson mobile comm ab；
Fig. 4 is that multispectral irradiation mould group uses in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention
The three dimensional structure diagram of multispectral Sony ericsson mobile comm ab；
Fig. 5 is multiple lenticules on microlens array in a kind of multispectral Sony ericsson mobile comm ab provided in an embodiment of the present invention
Arrangement schematic diagram；
Fig. 6 (a) is to be used as light after a kind of multispectral Sony ericsson mobile comm ab in the prior art forms multispectral irradiation mould group
The structural schematic diagram of dynamic therapy light source；
Fig. 6 (b) is the structural schematic diagram of the multispectral Sony ericsson mobile comm ab in Fig. 6 (a)；
Fig. 7 (a) is that the multispectral Sony ericsson mobile comm ab of another kind in the prior art forms conduct after multispectral irradiation mould group
The structural schematic diagram of optical dynamic therapy light source；
Fig. 7 (b) is the structural schematic diagram of the multispectral Sony ericsson mobile comm ab in Fig. 7 (a)；
Fig. 8 is that multispectral irradiation mould group uses in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention
The arrangement schematic diagram of solid-state light emitting element in multispectral Sony ericsson mobile comm ab；
Fig. 9 is that multispectral irradiation mould group uses in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention
Three kinds of different wave length light are in the uniform light spots region that target target surface is formed in multispectral Sony ericsson mobile comm ab；
Figure 10 be in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention first optical lens array with
The simulation result diagram that the distance change of second optical lens array influences hot spot even results；
Figure 11 (a) is the first optical lens array in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention
Hot spot even results are influenced in X-direction location dislocation in the X-Y plane perpendicular to optical axis with the second optical lens array
Simulation result diagram；
Figure 11 (b) is the first optical lens array in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention
Location dislocation influences hot spot even results in the Y direction in the X-Y plane perpendicular to optical axis with the second optical lens array
Simulation result diagram；
Figure 12 is that three kinds of different wave length light exist in a kind of optical dynamic therapy light-source system provided in an embodiment of the present invention
The illumination power density distribution curved surface on target target surface surface；
Figure 13 is a kind of decomposition texture schematic diagram of optical dynamic therapy irradiator provided in an embodiment of the present invention.
Wherein, the 1, first optical lens array, the 2, second optical lens array, 3, wiring board, 4, multispectral solid luminescent
Device, 401, package substrate, 402, reflector, 403, solid-state light emitting element, 404, electrode, 405, microlens array, 4051, micro-
Lens, 406, plane packaging structure, 407, hemispherical lens structure, 5, light transmission protective plate, 6, target target surface, 7, drive end bearing bracket, 8,
Rear end cap.
Specific embodiment
In order to enable those skilled in the art to better understand the solution of the present invention, below in conjunction in the embodiment of the present invention
Attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is only
The embodiment of a part of the invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill people
The model that the present invention protects all should belong in member's every other embodiment obtained without making creative work
It encloses.
It should also be noted that similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi
It is defined in a attached drawing, does not then need that it is further defined and explained in subsequent attached drawing.
Shown in referring to Figures 1 and 2, the embodiment of the invention discloses a kind of optical dynamic therapy light-source systems, including successively
Multispectral irradiation mould group, the first optical lens array 1 and the second optical lens array 2 disposed in parallel；Multispectral irradiation mould group
Including wiring board 3 and at least one can generate the parallel collimation of more different wave lengths and the mostly light of the uniform light pencil of hot spot
Sony ericsson mobile comm ab 4 is composed, in the orthogonal thereto array arrangement assist side 3 of each multispectral Sony ericsson mobile comm ab 4；First optical lens battle array
Have the side of the refractive lenslet of multiple orthogonal thereto array arrangements towards multispectral irradiation mould group, the second optical lens on column 1
The side of refractive lenslet on lens array 2 with multiple orthogonal thereto array arrangements is backwards to multispectral irradiation mould group, the second light
Each lenslet on lens array 2 is overlapped with the center of each lenslet on the first optical lens array 1 and each side one is a pair of
It answers；Multispectral irradiation mould group is 3~5mm, the first optical lens array 1 and the second light at a distance from the first optical lens array 1
The distance of lens array 2 is 0.85~1.15 times of the focal length of lenslet.
In the present embodiment, in the multispectral irradiation mould group for generating optical dynamic therapy illumination beam, it is on wiring board
Orthogonal array, which has been arranged, can generate the hair of the multispectral solid-state of collimation and the uniform light pencil of hot spot in parallel of more different wave lengths
Optical device.After being arranged in this way, multiple multispectral Sony ericsson mobile comm abs form an area source, each multispectral Sony ericsson mobile comm ab
Generate the parallel collimation and the uniform light pencil of hot spot of more different wave lengths, thus entire multispectral irradiation mould group can produce and
The identical respective independent parallel beamlet of the quantity of multispectral Sony ericsson mobile comm ab, wherein each beamlet is by more thin light
Beam is constituted, and there are gap between each beamlet, more beamlets constitute an angle pencil of ray again, so as to control for light power
It treats and enough illumination power densities is provided.
In practical applications, consider for heat dissipation and installation, adjacent multispectral solid luminescent in multispectral irradiation mould group
It must there are certain gaps between device.Therefore, if these each auto-collimations, uniform light beam are projected directly at target
Face, i.e. patient's treatment zone, uniform hot spot can not adjoin one another in target target surface and join together each other.
To solve the above problems, having set gradually the first optical lens battle array before the light-emitting surface of multispectral irradiation mould group
Column and the second optical lens array, while also making the refractive on the first optical lens array with multiple orthogonal thereto array arrangements
The side of lenslet is towards multispectral irradiation mould group, with the refraction of multiple orthogonal thereto array arrangements on the second optical lens array
Each lenslet and first optical lens battle array of the side of type lenslet in multispectral irradiation mould group, the second optical lens array
The center of each lenslet on column is overlapped and each side corresponds.
Meanwhile multispectral irradiation mould group is set as 3~5mm at a distance from the first optical lens array.First optical lens
The incident light of array is the emergent light of multispectral irradiation mould group, which is the directional light of myopia, theoretically the first optical lens
Lens array is closer at a distance from spectral illumination mould group, and for the first optical lens array, incident light is more parallel.However,
In view of practical application and assembly technology, the two distance controlling can be met into needs in the range of 3~5mm.
For the first optical lens array, incident light is an angle pencil of ray, which is respectively only by more
Stand what parallel beamlet was constituted, and each light pencil is uniformly thin by the parallel collimation and hot spot of more different wave lengths
What light beam was constituted.It is multiple small on the first optical lens array when the angle pencil of ray is incident on the first optical lens array
Above-mentioned angle pencil of ray is split into more small light beams identical with the quantity of lenslet again by mirror, at this time in every small beam range
Uniformity is substantially superior to the uniformity within the scope of angle pencil of ray.
Further, the second optical lens array is set in parallel near the back focal plane of the first optical lens array
Place, i.e. the first optical lens array are 0.85~1.15 times of the focal length of lenslet at a distance from the second optical lens array.The
Each lens on two optical lens arrays reassemble the light that lenslet outgoing is corresponded on the first optical micro lens array
After be emitted on target target surface, on radiation exposed target target surface surface, each hot spot is overlapped mutually and inhomogeneities mutually compensates,
To realize the Uniform Irradiation to target target surface.
In the present embodiment, the light angle of scattering of the different wave length of multispectral Sony ericsson mobile comm ab outgoing is constrained to approximate phase
Together, and collimation is carried out to light and hot spot is uniform, finally generated the parallel of more different wave lengths and collimate and the uniform thin light of hot spot
Beam；Multiple orthogonal thereto array arrangements of multispectral Sony ericsson mobile comm ab form an area source after constituting multispectral irradiation mould group, produce
Raw respective independent parallel beamlet identical with the quantity of multispectral Sony ericsson mobile comm ab, wherein each beamlet is by more
Light pencil is constituted, and more beamlets constitute an angle pencil of ray again, so as to provide enough illumination power for optical dynamic therapy
Density；The angle pencil of ray that multispectral irradiation mould group generates successively passes through the first optical lens array and the second optical lens array is defeated
Out, the Uniform Irradiation to target target surface is realized.
The optical dynamic therapy light-source system provided in the present embodiment, not only increases the efficiency of light energy utilization, greatly improves
Uniform illumination degree also makes illumination power density distribution curved surface height of the light of each different wave length in target target surface similar,
The multispectral combination therapy effect of light power of the multispectral Sony ericsson mobile comm ab as optical dynamic therapy light source when is improved to reach
Fruit.
Specifically, in the present embodiment, by 140 multispectral orthogonal thereto array arrangements of Sony ericsson mobile comm ab in 201 × 65mm
Wiring board on, wherein the horizontal spacing of each multispectral Sony ericsson mobile comm ab is 9mm, longitudinal pitch 9mm, to constitute 20
× 7 arrays, the multispectral irradiation mould group that area is 176 × 59mm.First optical lens array and the second optical lens array
Outer dimension is identical, is 203 × 68mm, slightly larger than the size of wiring board.Meanwhile first optical lens array and the second optics
Lens array is made of compact arranged 35 × 20 refractive lenslets, the two optical parameter having the same.
On the basis of the above embodiments, referring to shown in Fig. 3~Fig. 5, multispectral Sony ericsson mobile comm ab 4 includes package substrate
401, reflector 402 is provided on the loading end of package substrate 401, is provided at least two in the accommodation space of reflector 402
The solid-state light emitting element 403 of different wave length；401 two sides of package substrate are provided at least two pairs of electrodes 404, electrode 404 and solid-state
The positive and negative anodes of light-emitting component 403 are connected；It is also closed off at the light-emitting window of reflector 402 and is provided with microlens array 405, lenticule battle array
Column 405 are parallel with package substrate 404, and with the refractive hemispherical of multiple orthogonal thereto array arrangements on microlens array 405
The side of lenticule 4051 is backwards to solid-state light emitting element 403.
In the present embodiment, the transparent materials such as epoxy resin or silica gel is not used, reflector is filled, but reflecting
Closing is provided with a microlens array, the size of the size of the microlens array than the light-emitting window of reflector at the light-emitting window of cup
It is bigger, so that microlens array can cover all the light-emitting window of reflector, so that microlens array and each solid luminescent member
The distance of part fixes and each solid-state light emitting element is isolated with outside air, also makes the structure of entire device more compact,
Easy to produce and use.
After being arranged in this way, each solid-state light emitting element can be made directly to be exposed in air, so as to reduce etendue.
And the mode for using refractive index to be packaged for the transparent material of n to solid-state light emitting element, etendue can expand n2Times.
Meanwhile the microlens array can collect the light that each solid-state light emitting element is emitted in wide-angle light emitting region
Line, and form the parallel light pencil of identical with the quantity of the lenticule on microlens array more collimations.The result handled in this way
It is, it is different although set up the spatial position of each solid-state light emitting element on same package substrate, but for lenticule battle array
For each lenticule on column, it is on same position that the light of incident different wave length can be seen as by approximation
Point light source.Therefore, the light that each solid-state light emitting element issues is after microlens array collimates, each difference in light pencil
The Space Angle distributional difference of wavelength light is constrained for very little, and the light pencil of each different wave length is formed by light in target target surface
Spot is closely located to identical.Since the lenticule on microlens array is closely arranged, more light pencils are formed on target target surface
Hot spot be connected to each other, formed illumination power density distribution uniformly and position consistency large spot, light power can be effectively improved and controlled
The clinical effectiveness for the treatment of.The emergent ray being made of more light pencils is not ideal directional light, but has certain diverging
Angle, but because of its angle of divergence very little, so can be approximately considered is directional light.
It should be noted that the quantity of the lenticule on microlens array and the solid luminescent member being arranged on package substrate
The quantity of part is without direct relation.Under conditions of microlens array shape and size dimension determine, the lenticule that is arranged thereon
Quantity is determined by parameters such as the distance between the radiuses of lenticule, the rounded bottom surface of contiguous microlens.
Preferably, the light-emitting window of reflector be rectangle or circle, the light-emitting window of the shape and reflector of microlens array
Shape matches.In the present embodiment, the light-emitting window of reflector can be set to rectangle or circle, preferably circular, micro- at this time
Lens array is also correspondingly arranged as circle.This is because when the light-emitting window of reflector is round, it is easy to accomplish in technique.
In addition, the bottom surface of reflector is preferably consistent with the shape of its light-emitting window, when the light-emitting window of reflector is circle
When, bottom surface is also round.The size of the bottom surface of reflector and light-emitting window by entire multispectral Sony ericsson mobile comm ab ruler
Very little size determines, as process conditions permit, should select biggish size as far as possible.
Preferably, the height of reflector and the focal length of lenticule are identical.In the present embodiment, the height of reflector is by lenticule
The optical center of lenticule is determined to the distance between solid-state light emitting element surface in array, when preferably identical as the focal length of lenticule,
There can be preferable light-out effect.
Preferably, insulating surface layer is additionally provided on the loading end of package substrate, insulating surface layer is by thermal conductive ceramic material
It is made.In the present embodiment, package substrate setting is square, and is in the circuit board when facilitating the multispectral radiation source of subsequent composition
Orthogonal array arrangement.The ceramic material of insulating surface layer selection is generally the materials such as aluminium oxide or aluminium nitride, and insulation effect is preferable.
However, in the prior art conduct different from the structure of multispectral Sony ericsson mobile comm ab described in above-described embodiment
The multispectral Sony ericsson mobile comm ab of optical dynamic therapy light source generallys use plane packaging structure when packaged, or in the plane
A hemispherical lens structure is further added by the light output surface of encapsulating structure, encapsulating material generally uses epoxy resin or silica gel etc.
Transparent material.Below in conjunction with corresponding attached drawing first to the structure of both multispectral Sony ericsson mobile comm abs in the prior art with
And existing defect is described in detail.
Referring to shown in Fig. 6 (a), Fig. 6 (a) is that a kind of multispectral Sony ericsson mobile comm ab in the prior art forms multispectral photograph
Penetrate the structural schematic diagram after mould group as optical dynamic therapy light source.It is made of the LED chip of three different wave lengths multispectral
Sony ericsson mobile comm ab is arranged in array forms multispectral irradiation mould group in the circuit board, when as optical dynamic therapy light source,
The light beam of the different wave length of sending, by being irradiated to target target surface 6 after being mounted on light transmission protective plate 5 behind.In target
6 surface of face, the interlaced overlapping of hot spot caused by the light beam of each different wave length, connection in flakes, form the hot spot of large area.
Referring to shown in Fig. 6 (b), Fig. 6 (b) is shown in Fig. 6 (a) in the prior art using the more of plane packaging structure
The structural schematic diagram of spectrum Sony ericsson mobile comm ab.In the multispectral Sony ericsson mobile comm ab, including red LED chip, green light LED core
Solid-state light emitting element 403 including piece and blue-light LED chip is integrated on same package substrate 401, while each LED chip
With corresponding electrode 404 connect, then reflector 402 is filled using transparent materials such as epoxy resin or silica gel to be formed it is flat
Face encapsulating structure 406.
From in Fig. 6 (b) as can be seen that the light that is emitted from each LED chip by plane packaging structure surface with
Reflection and refraction occur when the interface of air.When the angle of incidence is larger than a critical angle, it may occur that total reflection, light cannot be emitted to
In air, that is, there is " the evolution cone " of critical angle, to reduce the efficiency of light extraction of multispectral Sony ericsson mobile comm ab entirety.This
Outside, due to the lambertian distribution that the radiation angle of the light of each LED chip outgoing is in 110~120 °, the hair of excessive emergent ray
Scattered angle disperses energy of light source.
Obviously, the multispectral irradiation mould group formed using the multispectral Sony ericsson mobile comm ab of structure shown in Fig. 6 (b), is deposited
In following defect: although reaching target target surface surface by the light beam of each multispectral Sony ericsson mobile comm ab outgoing is formed by hot spot
It can be connected with each other in flakes, but since the efficiency of light extraction of each multispectral Sony ericsson mobile comm ab is lower, and because the angle of divergence is excessive
Energy of light source is caused to be dispersed, although so that the facula area for being radiated at target target surface surface is big, the illumination function of each position
Rate density is but very low, it is difficult to meet requirement of the optical dynamic therapy to effective irradiation area light according to power density, clinical therapeutic efficacy
It is bad.
Referring to shown in Fig. 7 (a), Fig. 7 (a) is that the multispectral Sony ericsson mobile comm ab composition of another kind in the prior art is multispectral
Irradiate the structural schematic diagram after mould group as optical dynamic therapy light source.Similarly, it is made of the LED chip of three different wave lengths
Multispectral Sony ericsson mobile comm ab be arranged in array and form multispectral irradiation mould group in the circuit board, used up as optical dynamic therapy
When source, the light beam of the different wave length issued arrives target target surface 6 by irradiation after being mounted on light transmission protective plate 5 behind.?
The position on 6 surface of target target surface, hot spot caused by the light beam of each different wave length is different, each other independently of each other, cannot
Connection in flakes, does not become the equally distributed spot area of illumination power density.
Referring to shown in Fig. 7 (b), Fig. 7 (b) is to use in the prior art in plane packaging structure shown in Fig. 7 (a)
The structural schematic diagram of the multispectral Sony ericsson mobile comm ab of a hemispherical lens structure is further added by light output surface.This is multispectral solid
On the basis of state luminescent device is only the structure shown in Fig. 6 (b), a hemisphere is increased again on plane packaging structure 406
Shape lens arrangement 407.
It obviously, is in 110~120 ° of lambertian distribution to the radiation angle that each LED chip is emitted by hemispherical lens structure
Light converged, become the light of gaussian distribution with the specific angle of divergence, and the energy for emitting light beam is concentrated on into light
Near axis.In addition, hemispherical lens structure changes the propagation side for the light of each LED chip outgoing being located in " evolution cone "
To plane packaging structure can be escaped, to improve the multispectral solid state illuminator with structure shown in Fig. 7 (b)
The efficiency of light extraction of part.
When the orthogonal thereto array arrangement of multispectral Sony ericsson mobile comm ab shown in Fig. 7 (b) is constituted mostly light in the circuit board
When spectrum irradiation mould group, the considerations of for heat dissipation with installation, need between each multispectral Sony ericsson mobile comm ab there are gap,
As a result it will lead to hot spot that collimation and parallel light beam from the outgoing of multispectral Sony ericsson mobile comm ab are formed in target target surface not
It can be connected to be a piece of, the illumination power density of each position made to form difference.
Certainly, to solve this problem, can be made by increasing the distance between multispectral irradiation mould group and target target surface
Each mutually independent hot spot that target face must be reached is connected with each other.It is each on target target surface but with the increase of the distance
The illumination power density of position will decline therewith, it is difficult to meet optical dynamic therapy and want to effective irradiation area light according to power density
It asks, clinical therapeutic efficacy is bad.
Further, since the refractive index of hemispherical lens structure increases with the reduction of lambda1-wavelength, three LED chips go out
In the light penetrated, the smallest blue light refractive index of wavelength is maximum, and the maximum feux rouges refractive index of wavelength is minimum.When light is from hemispherical
When lens arrangement is traveled in air, the small light of refractive index can be biased to the edge of hemispherical lens structure.
Above-mentioned two factor shines optical dynamic therapy light source shown in Fig. 7 (a) using the light of different wave length
When penetrating target target surface, the light of different wave length is formed by hot spot will be different in the position that target target surface surface occurs, and
This difference will exist always, can't reduce because of multispectral irradiation mould group and the increase of the distance between target target surface, this
Illumination power density distribution curved surface difference in kind effective irradiation region will be unfavorable for realizing multispectral smooth power link treatment
Validity.
In conclusion multispectral Sony ericsson mobile comm ab in the prior art there are efficiency of light extraction low, each different wavelengths of light
Line is applied if will directly form multispectral irradiation mould group after its array arrangement the facula position difference of target target surface the defects of
In optical dynamic therapy, it will lead to and occur that the efficiency of light energy utilization is low, uneven illumination is even, the irradiation hot spot of different wave length is in treatment region table
Face position is inconsistent, treatment region surface Compound eye power density distribution curve form differs greatly etc. a series of asks
Topic constrains the application and development of optical dynamic therapy light source to keep optical dynamic therapy clinical effectiveness bad.
Compared with two kinds of encapsulating structures in the prior art, it is arranged in multispectral Sony ericsson mobile comm ab described in the present embodiment
Microlens array significantly reduce the thickness of lens, thus greatly reduce energy loss of the light in lens.Therefore, lead to
It crosses at the light-emitting window of reflector and encapsulates the microlens array, the efficiency of light extraction for not only solving multispectral Sony ericsson mobile comm ab is asked
Topic, but also the Space Angle of each different wave length light can be constrained to approximately uniform.
On the basis of the above embodiments, solid-state light emitting element 403 includes having peak in 620~630nm wave-length coverage
It is worth the red LED chip of wavelength, the green LED chip in 520~530nm wave-length coverage with peak wavelength and 460
With the blue-light LED chip of peak wavelength in~470nm wave-length coverage.
In the present embodiment, solid-state light emitting element is preferably respectively in above-mentioned wave-length coverage with the feux rouges of peak wavelength
LED chip, green LED chip and blue-light LED chip, due to the peak value of the extinction spectrum of most photosensitizer be 625nm or
525nm or 465nm, so it can satisfy most of optical dynamic therapy to the particular demands of the wavelength of light.
Certainly, for certain photosensitizers, according to its extinction spectrum characteristic, those skilled in the art can be by solid luminescent member
Part is preferably respectively in above-mentioned wave-length coverage with red LED chip, yellow light LED chip and the blue-ray LED core of peak wavelength
Piece or other combinations.
Solid-state light emitting element preferably uses LED chip, can be with due also to LED chip, when lighting, the heat of sending is less
The sense of discomfort generated when the treatment region of patient is illuminated in reduction therapeutic process.
In addition, the two sides of package substrate are provided with three pairs of electrodes, three pairs of electrodes respectively with red LED chip, green light LED core
Piece is connected with the positive and negative anodes of blue-light LED chip, therefore each LED chip is lighted and extinguished and can be independently controlled, convenient to exist
Each LED chip is controlled when optical dynamic therapy.
On the basis of the above embodiments, referring to shown in Fig. 8, red LED chip, green LED chip and blue-light LED chip
Arrangement in equilateral triangle, red LED chip, green LED chip and the mutual distance of blue-light LED chip be 0.1~
0.2mm。
In the present embodiment, red LED chip, green LED chip and blue-light LED chip as solid-state light emitting element are in
Equilateral triangle arrangement, and it is the center of equilateral triangle and the plane of the light-emitting window of reflector is concentric, at this point for being encapsulated in
For microlens array on reflector light-emitting window, the location of these three LED chips are the same.
In addition, the gap between these three LED chips is configured smaller as far as possible, it is possible to reduce etendue.
Certainly, in practical applications, three LED chips are arranged into equilateral triangle is a kind of preferred arrangement side
Formula, other arrangement modes are also possible, and when the quantity of LED chip is not three, those skilled in the art will necessarily
It is arranged into other modes.
It should be noted that the red LED chip, green LED chip and blue-light LED chip in the present embodiment are specifically located
In which position of equilateral triangle be without limitation.
On the basis of the above embodiments, the radius of lenticule 4051 is 0.05~0.25mm, the focal length of lenticule 4051
For 0.8mm, the distance between the rounded bottom surface of contiguous microlens 4051 is 0mm.
In the present embodiment, microlens array is by multiple orthogonal thereto array arrangements backwards to the side of each solid-state light emitting element
What refractive hemispherical microlenses were formed.In Fig. 5, r is the radius of lenticule, and d is between the rounded bottom surface of contiguous microlens
Distance, D=2r+d are the distance between the center of circle of rounded bottom surface of contiguous microlens.
Further, Sony ericsson mobile comm ab multispectral in above-described embodiment is carried out using TracePro optical simulation software
Modeling and trace emulation analyze parameter r, d and D in microlens array to the efficiency of light extraction of the variant wavelength light of outgoing
It influences, to determine preferable lenticule parameter in the embodiment of the present invention.
Simulation result shows: when the radius of lenticule is 0.05~0.25mm, the center of circle of the rounded bottom surface of contiguous microlens
The distance between be 0.1~0.5mm when, efficiency of light extraction promoted effect it is obvious.At this point, between the rounded bottom surface of contiguous microlens
Distance d=0mm, effective aperture ratio [the π r of microlens array2/(2r+d)2The value of] × 100% is 78.5%.
Preferably, the radius of lenticule is 0.15mm, and the distance between rounded bottom surface of contiguous microlens is 0mm at this time
When, efficiency of light extraction is best.
According to above-mentioned preferred lenticule parameter, the making material of microlens array selects the wave to visible light to infrared light
The light of long range all has the optical glass of good light permeability.Since the diameter of lenticule is very small, and microlens array
On each lenticule closely arrange, therefore cannot be processed using cold processing technique means.In the present embodiment, using plasma
The production of etching method optics micro-processing technology progress microlens array.Further, since optical glass has compared with PMMA material, PC material
The frangible disadvantages such as material, can be by coating film treatment come the non-friable characteristic of improving optical glass.
Therefore, the distance between the radius of above-mentioned lenticule and the rounded bottom surface of contiguous microlens is the feelings of 0mm
Under condition, the focal length of each lenticule is 0.8mm on the microlens array that made by the material.
On the basis of the focal length and radius of lenticule has been determined, those skilled in the art can calculate according to common knowledge
The height of lenticule out, details are not described herein for the process.
On the basis of multispectral Sony ericsson mobile comm ab structure described in the various embodiments described above, the embodiment of the present invention is provided
Multispectral Sony ericsson mobile comm ab the efficiency of light energy utilization, to different wave length ray space angle constraint and hot spot it is uniform on effect
It is verified, is first defined as follows parameter:
The uniformity: Ai=Ei/Ep；
Coefficient of uniformity: E=Se/S。
In formula, EiThe illumination power density of the certain point for the hot spot that target target surface is formed is irradiated for light；EpFor light irradiation
The illumination power density peak value in hot spot that target target surface is formed；S is the gross area that light irradiates the hot spot that target target surface is formed；
SeIt is irradiated in the hot spot that target target surface is formed for light and meets AiThe area in >=0.85 region.
Wherein, Ai>=0.85 region is defined as uniform light spots region.Coefficient of uniformity E is higher, it is meant that light in hot spot
It is more uniform according to power density distribution.
When specific verifying, in the microlens array 150mm in multispectral luminescent device provided in an embodiment of the present invention
One target target surface is set at position, for simulating patient's treatment zone.Then, 620 are incident upon to target target surface respectively~
Feux rouges in 630nm wave-length coverage with peak wavelength, the green light in 520~530nm wave-length coverage with peak wavelength and
With the blue light of peak wavelength in 460~470nm wave-length coverage, the light of variant wavelength is measured in mesh using light irradiatometer
The illumination power density of the hot spot formed on target face.
Specifically, target target surface is divided into the square measurement subregion of 10 × 10mm, measurement target is each measurement
The illumination power density values for measuring target are denoted as E by the geometric center point in regioni, respectively according to the public affairs of the above-mentioned calculating uniformity
Formula calculates the uniformity A of measurement targeti.The light of three kinds of different wave lengths is formed by hot spot outermost in the same coordinate system
Middle Ai>=0.85 point is connected with broken line, forms three closed regions as shown in Figure 9, which is three kinds of different wave lengths
Each self-forming of light uniform light spots region.
From fig. 9, it can be seen that the area in the uniform light spots region of each self-forming of the light of three kinds of different wave lengths is essentially identical,
And integrated distribution, at the center of hot spot, position of three uniform light spots regions on target target surface substantially overlaps.
Then, using integrating sphere respectively to multispectral Sony ericsson mobile comm ab and the embodiment of the present invention shown in Fig. 6 (a)
Efficiency of light extraction of the multispectral Sony ericsson mobile comm ab provided when being emitted different wave length light measures, and the present invention is implemented
The measurement numerical value for the multispectral Sony ericsson mobile comm ab that example provides is relative to multispectral Sony ericsson mobile comm ab shown in Fig. 6 (a)
Measurement numerical value is normalized, and obtains the variant wavelength light of multispectral Sony ericsson mobile comm ab provided in an embodiment of the present invention
Line normalizes the numerical value of efficiency of light extraction, shown in table specific as follows.
| Light source peak wavelength | 625nm | 525nm | 465nm |
| Normalize efficiency of light extraction | 51.50% | 46.40% | 48.70% |
As can be seen from the above table, etendue can be effectively reduced by the way that solid-state light emitting element to be exposed in air
Amount, while encapsulating microlens array at the light-emitting window of reflector can be such that the efficiency of light extraction of variant wavelength light obtains very
It is apparent to improve.The actual measured value of the normalization efficiency of light extraction of variant wavelength light and it is above-mentioned using optical simulation software into
The result of row analog simulation matches.
In conclusion multispectral Sony ericsson mobile comm ab provided in an embodiment of the present invention, not only has efficiency of light extraction height, encapsulation
The advantages that Space Angle of small in size, variant wavelength light is approximately uniform, light collimation is parallel, hot spot is uniform, and it is variant
Wavelength light is also approximately uniform in the uniform light spots position of target target surface, effectively improves the clinical effectiveness of optical dynamic therapy.
On the basis of the above embodiments, the first optical lens array 1 and the lenslet on the second optical lens array 2 are tight
Solid matter column, lenslet are regular hexagon or rectangle.
In the present embodiment, in order to realize the seamless of the first optical lens array and the lenslet on the second optical lens array
Close arrangement, the bottom surface of lenslet is preferably regular hexagon or rectangle.
Specifically, in the present embodiment, the bottom surface of lenslet is preferably rectangle.The size of each lenslet be 5.8mm ×
3.4mm, lenslet are 2.9mm in the half-breadth of X-direction, and half-breadth in the Y direction is 1.7mm, focal length 15mm.
Compared with the microlens array being arranged in multispectral Sony ericsson mobile comm ab, the first optical lens array and the second optics
The size of lenslet on lens array is larger, thus the first optical lens array can be selected with the second optical lens array it is poly-
The production of methyl methacrylate (PMMA) material, is implemented by mold processing scheme.
On the basis of the above embodiments, the first optical lens array 1 is at a distance from the second optical lens array 2 and small
The focal length of mirror is identical.
In the present embodiment, since in actual installation process, there are the factors such as part and rigging error, above-mentioned to realize
The accurate positioning of the distance between first optical lens array and the second optical lens array, and guarantee the second optical lens battle array
Each lenslet on column is overlapped with each lenslet center on the first optical lens array and each side corresponds, must
It can so take a substantial amount of time and energy, the defect for causing cost performance unexcellent.
Therefore, TracePro optical simulation software is used to carry out wavelength for the light of the feux rouges of 625nm in the present embodiment
Trace simulation, for analyzing the distance between the first optical lens array and the second optical lens array to the shape on target target surface
At uniform light spots area SeWith the influence of coefficient of uniformity E, while also be used to analyze the first optical lens array and the second light
Lens array is in the X-Y plane perpendicular to optical axis to the uniform light spots formed on target target surface when appearance position dislocation
Area SeWith the influence of coefficient of uniformity E.
Parameter described in above-described embodiment etc. is imported in the optical simulation software, to the first optical lens array and the
Area S of the variation of distance to the uniform light spots formed on target target surface between two optical lens arrayseWith coefficient of uniformity E's
Influence is emulated, then carries out data processing to obtained simulation result by Matlab, obtains curve as shown in Figure 10.
Pass through distance between coefficient of uniformity E and the first optical lens array and the second optical lens array shown in Figure 10
Relation curve to can be seen that the distance between two optical lens arrays uniform to the hot spot of entire optical dynamic therapy light source
Effect significantly affects.When distance between the two is the focal length of the lenslet on array, the even results of hot spot are best,
When the focal length 15mm of lenslet described in as above-mentioned the present embodiment, while it is also seen that distance between the two in array
On lenslet focal length before and after the uniformity of hot spot will not be made to occur significant changes when variation in 15% range, but when exceeding this
The uniformity of hot spot can be remarkably decreased after one range.Therefore, the first optical lens array is at a distance from the second optical lens array
It is 0.85~1.15 times of the focal length of lenslet, when the distance is the focal length of lenslet, effect is best.
Meanwhile the area S for passing through uniform light spots shown in Figure 10eWith the first optical lens array and the second optical lens
The relation curve of distance can also be seen that the area Se of hot spot gross area S and uniform light spots with two optical lens between array
The increase of distance between lens array and decline.
Further, the second optical lens array and the first optical lens array go out in the X-Y plane perpendicular to optical axis
When existing location dislocation, the lenslet center coincidence of the first optical lens array and the second optical lens array and each side one can be destroyed
One-to-one correspondence.When offset is smaller, remain to project by the light of each lenslet on the first optical lens array
On to the second optical lens array on corresponding lenslet, hot spot effect is unaffected, and only facula position is lacked
The offset of amount, for the light of different wave length, the offset of facula position is identical.When offset is more than a fixed limit
After degree, other lenslets on the second optical lens array will be entered by the light of lenslet on the first optical lens array
In, the shape of hot spot can be destroyed.When offset continues to increase, the first optical lens array and the second optical lens array energy again
The center for forming new each lenslet is overlapped and the one-to-one relationship in each side, and hot spot effect restores normal.
Using TracePro optical simulation software to the first optical lens array and the second optical lens array perpendicular to
The influence of the area Se and coefficient of uniformity E of the uniform light spots that appearance position dislocation forms target target surface in the X-Y plane of optical axis
It is emulated, then data processing is carried out to obtained simulation result by Matlab, obtained such as institute in Figure 11 (a) and Figure 11 (b)
The curve shown.Wherein, complete in the X-Y plane perpendicular to optical axis with the first optical lens array and the second optical lens array
The position of alignment is coordinate origin.
By being can be seen that in Figure 11 (a) and Figure 11 (b) when the first optical lens array and the second optical lens array exist
The offset of X-direction be no more than 2.5mm, and offset in the Y direction be no more than 1.5mm when, hot spot gross area S, uniform light spots
Area SeIt is varied less with what coefficient of uniformity E occurred.When the offset of the first optical lens array and the second optical lens array
Measure close to lenslet half-breadth size when, i.e., close to lenslet described in above-described embodiment X-direction half-breadth 2.9mm, in Y
When the half-breadth 1.7mm in direction, hot spot effect can just be interfered significantly with.
In conclusion the first optical lens array is the 0.85 of the focal length of lenslet at a distance from the second optical lens array
At~1.15 times or the first optical lens array and second optical lens array are in the X-Y plane perpendicular to optical axis
The offset of appearance is much smaller than the location dislocation of half width values of lenticule, will not to the uniformity for the light being irradiated on target face
Significant changes occur.Since the light uniformity of output is between the first optical micro lens array and the second optical micro lens array
Distance change and installation offset it is insensitive in a certain range so that installing in practical applications simpler, conveniently.
On the basis of optical dynamic therapy light-source system described in the various embodiments described above, further to the embodiment of the present invention
The optical dynamic therapy of offer is tested with the illumination power density that light source carries out three kinds of different wave length light, to obtain variant wavelength
The illumination power density distribution situation of light.
Firstly, in clinical application be usually by photodynamic therapy light source between patient's treatment zone at a distance from be maintained at
Within the scope of 250~350mm, therefore a target is set at the position apart from the second above-mentioned optical lens array 300mm
Face, for simulating patient's treatment zone.Then, being incident upon in 620~630nm wave-length coverage to target target surface respectively has peak value
The feux rouges of wavelength, in 520~530nm wave-length coverage with peak wavelength green light and have in 460~470nm wave-length coverage
There is the blue light of peak wavelength, uses the illumination function for the hot spot that the light that light irradiatometer measures each wavelength is formed on target target surface
Rate density.
Specifically, target target surface is divided into the square measurement subregion of 10 × 10mm, measurement target is each measurement
The illumination power density values for measuring target are denoted as Ei by the geometric center point in region, while using three-dimensional mapping software, with measurement
The illumination power density values E of targetiFor Z axis coordinate value, measurement target be x, y-coordinate value, illumination is constructed in three-dimensional system of coordinate
Power density curved surface.According to the method, the illumination for the hot spot that different wave length light is formed on target target surface in three is respectively obtained
Power density curved surface, and place them in the same coordinate system, referring to Fig.1 shown in 2.
It can be recognized from fig. 12 that the light of three kinds of different wave lengths is collimated successively by the first optical lens array and the
After two optical lens arrays homogenization, the large area hot spot of homogenization is formd on target target surface, and its illumination power is close
It is similar to spend distribution surface height, is moved to reach raising and be applied using multispectral radiation source provided in an embodiment of the present invention in light
The effect of the multispectral combination therapy mode of light power when power is treated.
Referring to Fig.1 shown in 3, the embodiment of the invention also discloses a kind of optical dynamic therapy irradiator, which includes front end
Lid 7, rear end cap 8 and the light power as described in any one of above-described embodiment being arranged between drive end bearing bracket 7 and rear end cap 8 are controlled
Treatment light-source system.
It include successively multispectral irradiation mould group disposed in parallel, the in the present embodiment, in optical dynamic therapy light-source system
One optical lens array and the second optical lens array, wherein multispectral irradiation mould group is positioned close to the side of rear end cap, the
Two optical lens arrays are positioned close to the side of drive end bearing bracket.
Preferably, optical dynamic therapy is at least one radiator fan is additionally provided between light source and rear end cap, i.e., setting exists
Between multispectral irradiation mould group and rear end cap, for radiating to multispectral irradiation mould group, also it can effectively avoid because multispectral
The heat that irradiation mould group generates makes patient generate sense of discomfort.
In practical applications, the light that multiple multispectral irradiation mould group close-packed arrays form a plane or cambered surface can be moved
Power treatment light source, keeps its effective irradiated area bigger, the first optical lens array and the second optical lens of corresponding setting
Lens array is also a plane or an arc surface.If multiple multispectral irradiation mould group close-packed arrays form a cambered surface, the first optical lens
The cambered surface for the cambered surface that the cambered surface curvature of array and the second optical lens array and multiple multispectral irradiation mould group close-packed arrays are formed
Curvature is identical.
It should be noted that the multispectral shape for irradiating mould group, the first optical lens array and the second optical lens array,
Size etc. can make corresponding change according to light irradiation situation to realize expected technical effect, these changes are
It makes, should all be included in the protection scope of the present invention within the spirit and principles in the present invention.
In the description of the present invention, it should be noted that the orientation or position of the instructions such as term " on ", "lower", "inner", "outside"
Set relationship be based on the orientation or positional relationship shown in the drawings or the invention product using when the orientation or position usually put
Relationship is set, is merely for convenience of description of the present invention and simplification of the description, rather than the device or element of indication or suggestion meaning are necessary
It with specific orientation, is constructed and operated in a specific orientation, therefore is not considered as limiting the invention.
In addition, term " first ", " second ", " third " etc. are only used for distinguishing description, it is not understood to indicate or imply
Relative importance.
In the description of the present invention, it is also necessary to which explanation is unless specifically defined or limited otherwise, term " setting ",
" installation ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally connect
It connects；It can be mechanical connection, be also possible to be electrically connected；It can be directly connected, can also indirectly connected through an intermediary, it can
To be the connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood with concrete condition
Concrete meaning in the present invention.
In the above embodiment of the invention, it all emphasizes particularly on different fields to the description of each embodiment, does not have in some embodiment
The part of detailed description, reference can be made to the related descriptions of other embodiments.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and
Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of optical dynamic therapy light-source system, which is characterized in that including successively multispectral irradiation mould group disposed in parallel,
One optical lens array and the second optical lens array；The multispectral irradiation mould group includes wiring board and at least one can
The parallel collimation of more different wave lengths and the multispectral Sony ericsson mobile comm ab of the uniform light pencil of hot spot are generated, it is each described multispectral
The orthogonal thereto array arrangement of Sony ericsson mobile comm ab is on the wiring board；
The side of refractive lenslet on first optical lens array with multiple orthogonal thereto array arrangements is described in
Multispectral irradiation mould group, one of the refractive lenslet on second optical lens array with multiple orthogonal thereto array arrangements
Each lenslet and the first optical lens battle array of the side back to the multispectral irradiation mould group, on second optical lens array
The center of each lenslet on column is overlapped and each side corresponds；The multispectral irradiation mould group and the first optical lens battle array
The distance of column is 3~5mm, and first optical lens array is the lenslet at a distance from second optical lens array
0.85~1.15 times of focal length.
2. optical dynamic therapy light-source system according to claim 1, which is characterized in that the multispectral solid state illuminator
Part includes package substrate, and reflector, setting in the accommodation space of the reflector are provided on the loading end of the package substrate
There is the solid-state light emitting element of at least two different wave lengths；The package substrate two sides are provided at least two pairs of electrodes, the electrode
It is connected with the positive and negative anodes of the solid-state light emitting element；
It is also closed off at the light-emitting window of the reflector and is provided with microlens array, the microlens array and the package substrate are flat
Row, and the side of the refractive hemispherical microlenses on the microlens array with multiple orthogonal thereto array arrangements is backwards to described
Solid-state light emitting element.
3. optical dynamic therapy light-source system according to claim 2, which is characterized in that the solid-state light emitting element includes
Red LED chip in 620~630nm wave-length coverage with peak wavelength has peak in 520~530nm wave-length coverage
It is worth the green LED chip of wavelength and in 460~470nm wave-length coverage with the blue-light LED chip of peak wavelength.
4. optical dynamic therapy light-source system according to claim 3, which is characterized in that the red LED chip, described
Green LED chip and blue-light LED chip arrangement in equilateral triangle, the red LED chip, the green LED chip
It is 0.1~0.2mm with the mutual distance of the blue-light LED chip.
5. optical dynamic therapy light-source system according to claim 2, which is characterized in that the radius of the lenticule is
0.05~0.25mm, the focal length of the lenticule are 0.8mm, and the distance between rounded bottom surface of the adjacent lenticule is 0mm.
6. optical dynamic therapy light-source system according to claim 5, which is characterized in that the radius of the lenticule is
0.15mm。
7. optical dynamic therapy light-source system according to claim 2, which is characterized in that the height of the reflector and institute
The focal length for stating lenticule is identical.
8. optical dynamic therapy light-source system according to claim 1, which is characterized in that first optical lens array
With the lenslet close-packed arrays on second optical lens array, the lenslet is regular hexagon or rectangle.
9. optical dynamic therapy light-source system according to claim 1, which is characterized in that first optical lens array
And it is identical as the focal length of the lenslet at a distance from second optical lens array.
10. a kind of optical dynamic therapy irradiator, which is characterized in that including drive end bearing bracket, rear end cap and be arranged in the drive end bearing bracket
Between the rear end cap such as optical dynamic therapy light-source system according to any one of claims 1 to 9.
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| CN111659023A (en) * | 2020-07-07 | 2020-09-15 | 深圳厚屹节能技术有限公司 | Multispectral cosmetic lamp |
| ES2928172A1 (en) * | 2021-05-14 | 2022-11-15 | Univ Alcala Henares | LIGHTING DEVICE WITH ORIENTED LED DIODES (Machine-translation by Google Translate, not legally binding) |
| WO2022238609A1 (en) * | 2021-05-14 | 2022-11-17 | Universidad De Málaga | Lighting device with oriented led diodes |
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