CN109135680A - One kind keeping the temperature 12 ~ 18 DEG C of phase change cold accumulating agents for insulin - Google Patents
One kind keeping the temperature 12 ~ 18 DEG C of phase change cold accumulating agents for insulin Download PDFInfo
- Publication number
- CN109135680A CN109135680A CN201710506781.5A CN201710506781A CN109135680A CN 109135680 A CN109135680 A CN 109135680A CN 201710506781 A CN201710506781 A CN 201710506781A CN 109135680 A CN109135680 A CN 109135680A
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- Prior art keywords
- phase change
- cold
- insulin
- temperature
- phase
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Classifications
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K5/00—Heat-transfer, heat-exchange or heat-storage materials, e.g. refrigerants; Materials for the production of heat or cold by chemical reactions other than by combustion
- C09K5/02—Materials undergoing a change of physical state when used
- C09K5/06—Materials undergoing a change of physical state when used the change of state being from liquid to solid or vice versa
- C09K5/066—Cooling mixtures; De-icing compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
- Y02E60/14—Thermal energy storage
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Physics & Mathematics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Combustion & Propulsion (AREA)
- Thermal Sciences (AREA)
- Materials Engineering (AREA)
Abstract
The present invention relates to one kind to keep the temperature 12 ~ 18 DEG C of phase change cold accumulating agents for insulin, belongs to biologics field of thermal insulation.The present invention is made after adding hexadecane and expanded graphite mixing homogeneous using phase change paraffin as raw material.Phase change cold-storage agent material prepared by the present invention can be improved ice storage, and phase transition temperature is at 12 ~ 18 DEG C, and for latent heat of phase change up to 260 ~ 290kJ/kg, latent heat of phase change is high, and cold accumulation effects are good；For phase-change material for cold storage prepared by the present invention in flowing shape, viscosity is smaller, is easy to implement industrialized production.
Description
Technical field
The present invention relates to one kind to keep the temperature 12~18 DEG C of phase change cold accumulating agents for insulin, belongs to biologics field of thermal insulation.
Background technique
With the improvement of people ' s living standards, the change of the accelerating rhythm of life and living habit, diabetic's number are in
The trend now risen year by year, while tending to rejuvenation.Especially suffer fromThe patient of patients with type Ⅰ DM, it is necessary to rely on hormone pancreas
Island element carries out blood glucose-control.Insulin belongs to a kind of biological agent, and storage and preservation have stringent environmental condition, do not break a seal
Insulin long-term preservation, the insulin after not breaking a seal or breaking a seal need to can be housed in 2~25 DEG C of temperature under 2~8 DEG C of temperature environments
Spend short-term preservation under environment.The holding conditions of insulin seriously limitThe trip of the patient of patients with type Ⅰ DM.
The refrigerating box for insulin heat preservation occurred currently on the market is by active refrigeration, and soaking time is short, box body
It is heavier, bring trip inconvenient to patient.Therefore, right if can be realized passive refrigeration, long-time cold insulationThe patient of patients with type Ⅰ DM
Trip bring great convenience, for insulin heat preservation cold-storage material will have more vast market prospect.
Summary of the invention
The object of the present invention is to provide a kind of 12~18 DEG C of phase change cold accumulating agents, the phase change cold-storage for insulin heat preservation
Agent.
The present invention is a kind of for insulin 12~18 DEG C of phase change cold accumulating agents of heat preservation, it is characterised in that: by phase change paraffin, just
Hexadecane, expanded graphite are constituted, and mass fraction is as follows: phase change paraffin mass fraction is 8% ~ 30%, and hexadecane mass fraction is
50%~90%, expanded graphite mass fraction is 5%~15%.
Preferably, the phase transition temperature of the phase change paraffin is 12~18 DEG C.
Preferably, the addition of the hexadecane can further improve cold-storage material latent heat of phase change.
Preferably, the expanded graphite is expanded 30s in 700 DEG C of high temperature Muffle furnaces by expansible graphite, is in vermiform.
Preferably, the thermal conductivity of cold-storage material can be improved in the addition of the expanded graphite, realizes the quick cold-storage of cold-storage material.
Provided by the present invention for insulin keep the temperature 12~18 DEG C of phase change cold accumulating agents, compared with prior art, have compared with
High latent heat of phase change about 260~290kJ/kg, good cycling stability, processability is good, and cold-storage material phase alternating temperature provided by the invention
Degree is 12 DEG C~18 DEG C, meets the demand of the biologics storage environment temperature such as insulin, can be matched with ice bag, ice packet, ice chest etc.
It closes and uses.
Compared with prior art, of the invention to have the beneficial effect that:
1. rationally, simply, latent heat of phase change is big for cold-storage agent prescription of the invention；
2. cold-storage material of the invention uses organic material, the phase point that inorganic cold-storage material occurs in use is effectively prevented
From and surfusion；
3. cold-storage material safety of the invention, non-corrosive, mobility is strong, and processing difficulty is low.
Specific embodiment
The performance parameter of several example combination phase-change materials of the invention is described in detail below, so that of the invention
Advantages and features can be easier to be readily appreciated by one skilled in the art, to make to protection scope of the present invention apparent clear
Define.
Embodiment 1:
It is a kind of to keep the temperature the ingredient that 12~18 DEG C of phase change cold accumulating agents include following weight percents for insulin:
Phase change paraffin 10%
Hexadecane 80%
Expanded graphite 10%
For cold-storage material preparation process simple possible of the present invention, it can be achieved that industrialized production, stability is good, using DSC (differential scanning amount
Thermal method) measure the composition proportion cold-storage material phase transition temperature be 15.1 DEG C, latent heat of phase change 263.1kJ/kg.
Embodiment 2:
It is a kind of to keep the temperature the ingredient that 12~18 DEG C of phase change cold accumulating agents include following weight percents for insulin:
Phase change paraffin 20%
Hexadecane 72%
Expanded graphite 8%
For cold-storage material preparation process simple possible of the present invention, it can be achieved that industrialized production, stability is good, using DSC (differential scanning amount
Thermal method) measure the composition proportion cold-storage material phase transition temperature be 14.9 DEG C, latent heat of phase change 268.8kJ/kg.
Embodiment 3:
One kind keeping the temperature the ingredient that 12 ~ 18 DEG C of phase change cold accumulating agents include following weight percents for insulin:
Phase change paraffin 25%
Hexadecane 60%
Expanded graphite 15%
For cold-storage material preparation process simple possible of the present invention, it can be achieved that industrialized production, stability is good, using DSC (differential scanning amount
Thermal method) measure the composition proportion cold-storage material phase transition temperature be 15.7 DEG C, latent heat of phase change 270.8kJ/kg.
Above-described embodiment is only present pre-ferred embodiments, not does any type of limitation to the present invention.However,
For those of ordinary skill in the art, other various forms of variations can also be made on the basis of the above description
Or it changes.There is no necessity and possibility to exhaust all the enbodiments.And therefore amplified it is obvious variation or
It changes within still in the protection scope of the invention.
Claims (5)
1. a kind of keep the temperature 12 ~ 18 DEG C of phase change cold accumulating agents in insulin, it is characterised in that: by phase change paraffin, hexadecane, expansion stone
Ink is constituted, and mass fraction is as follows: phase change paraffin mass fraction is 8% ~ 30%, and hexadecane mass fraction is 50%~90%, expansion
Mass content of graphite is 5% ~ 15%.
2. 12 ~ 18 DEG C of phase change cold accumulating agents of a kind of insulin heat preservation described in claim 1, it is characterised in that: the phase change paraffin
Phase transition temperature is 12 ~ 18 DEG C.
3. 12 ~ 18 DEG C of phase change cold accumulating agents of a kind of insulin heat preservation described in claim 1, it is characterised in that: the hexadecane
Addition can further improve cold-storage material latent heat of phase change.
4. a kind of insulin described in claim 1 keeps the temperature 12 ~ 18 DEG C of phase change cold accumulating agents, it is characterised in that: the expanded graphite by
Expansible graphite is expanded 30s in 700 DEG C of high temperature Muffle furnaces, is in vermiform.
5. expanded graphite described in claim 4, it is characterised in that: the thermally conductive of cold-storage material can be improved in the addition of the expanded graphite
Property, realize the quick cold-storage of cold-storage material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710506781.5A CN109135680A (en) | 2017-06-28 | 2017-06-28 | One kind keeping the temperature 12 ~ 18 DEG C of phase change cold accumulating agents for insulin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710506781.5A CN109135680A (en) | 2017-06-28 | 2017-06-28 | One kind keeping the temperature 12 ~ 18 DEG C of phase change cold accumulating agents for insulin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109135680A true CN109135680A (en) | 2019-01-04 |
Family
ID=64805592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710506781.5A Pending CN109135680A (en) | 2017-06-28 | 2017-06-28 | One kind keeping the temperature 12 ~ 18 DEG C of phase change cold accumulating agents for insulin |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109135680A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111647388A (en) * | 2020-05-11 | 2020-09-11 | 广州大学 | Low-temperature composite phase-change coolant and preparation method thereof |
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| US20080010999A1 (en) * | 2004-09-27 | 2008-01-17 | Sgl Carbon Aktiengesellschaft | Device for cooling food |
| CN101429423A (en) * | 2008-12-01 | 2009-05-13 | 广州秀珀化工股份有限公司 | Nano-composite phase-changing material and preparation method |
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| CN102795805A (en) * | 2012-08-02 | 2012-11-28 | 成都新柯力化工科技有限公司 | Energy-saving phase-change constant-temperature building material and preparation method thereof |
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2017
- 2017-06-28 CN CN201710506781.5A patent/CN109135680A/en active Pending
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| US20080010999A1 (en) * | 2004-09-27 | 2008-01-17 | Sgl Carbon Aktiengesellschaft | Device for cooling food |
| CN101429423A (en) * | 2008-12-01 | 2009-05-13 | 广州秀珀化工股份有限公司 | Nano-composite phase-changing material and preparation method |
| CN101724381A (en) * | 2009-12-22 | 2010-06-09 | 中国科学技术大学 | Setting phase change energy storage material with high-thermal conductivity and preparation method thereof |
| CN102795805A (en) * | 2012-08-02 | 2012-11-28 | 成都新柯力化工科技有限公司 | Energy-saving phase-change constant-temperature building material and preparation method thereof |
| CN103804558A (en) * | 2012-11-15 | 2014-05-21 | 上海华明高技术（集团）有限公司 | Nano phase change material emulsion wide in temperature change range and preparation method thereof |
| CN105018038A (en) * | 2014-04-16 | 2015-11-04 | 上海艾尔派克包装材料有限公司 | Organic phase change thermal storage material and preparation method thereof |
| CN104164218A (en) * | 2014-07-09 | 2014-11-26 | 镇江新梦溪能源科技有限公司 | Heat storage material and preparation method thereof |
| CN104388055A (en) * | 2014-11-04 | 2015-03-04 | 镇江新梦溪能源科技有限公司 | Novel composite type organic-substance phase-change heat storage material and preparation method thereof |
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|---|---|---|---|---|
| CN111647388A (en) * | 2020-05-11 | 2020-09-11 | 广州大学 | Low-temperature composite phase-change coolant and preparation method thereof |
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Application publication date: 20190104 |