CN108992559A

CN108992559A - For preventing and treating the veterinary Chinese medicinal composition and preparation method thereof of anemopyretic cold and viral influenza

Info

Publication number: CN108992559A
Application number: CN201811279664.0A
Authority: CN
Inventors: 卜昌超; 陈冯硕; 徐进
Original assignee: Henan Hou Yi Industry Group Co Ltd
Current assignee: Henan Hou Yi Industry Group Co Ltd
Priority date: 2018-10-30
Filing date: 2018-10-30
Publication date: 2018-12-14

Abstract

The invention discloses a kind of for preventing and treating the veterinary Chinese medicinal composition and preparation method thereof of anemopyretic cold and viral influenza, belongs to technical field of Chinese medicine for animals.Its dosage form is Chinese herbal granules or soluble powder.Chinese medicine composition of the invention is made of the bulk pharmaceutical chemicals of following parts by weight: 150 ~ 300 parts of gypsum, 60 ~ 150 parts of rhizoma anemarrhenae, 60 ~ 150 parts of the root of Dahurain angelica, 100 ~ 200 parts of honeysuckle, 100 ~ 200 parts of wild chrysanthemum, 60 ~ 150 parts of Fructus Forsythiae, 20 ~ 40 parts of Baical Skullcap root P.E, 60 ~ 150 parts of cape jasmine, 60 ~ 150 parts of Radix Isatidis, 120 ~ 300 parts of folium isatidis, 100 ~ 200 parts of oriental wormwood, 100 ~ 200 parts of thick wood-fern rhizome, 100 ~ 200 parts of blackberry lily, 60 ~ 150 parts of dandelion, 60 ~ 150 parts of viola mandshurica, 60 ~ 150 parts of campanulaceae, 2 ~ 6 parts of borneol, 2 ~ 6 parts of menthol.The present invention has effects that clearing heat and detoxicating, cool blood detumescence according to monarch principle composition of prescription, all medicines share, is mainly used for influenza caused by treating livestock and poultry anemopyretic cold and virus, significant in efficacy, effect is rapid, and easy to use, and clinical value is high.

Description

For preventing and treating veterinary Chinese medicinal composition and its preparation of anemopyretic cold and viral influenza Method

Technical field

Present invention relates particularly to for preventing and treating anemopyretic cold and viral influenza veterinary Chinese medicinal composition and its preparation side Method belongs to technical field of Chinese medicine for animals.

Background technique

Winter, the disease incidence of influenza was high, and morbidity frequently, and has the tendency that evolving into chronic type due to the exception of weather, Cause a disease is influenza virus, parainfluenza virus, adenovirus and Respiratory Syncytial Virus(RSV) etc. originally.Currently, being adopted for viral disease more With chemotherapy, have a certain curative effect, but can be remained in body after drug use, directly affect the growth or life of livestock and poultry Produce performance.Though and biological products such as interferon, transfer factor, animal blood serum etc. are significant in efficacy, do not generate resistant strain, its valence Lattice are expensive, higher operating costs.Synthetic drug such as amantadine, moroxydine, virazole etc. has teratogenesis, mutagenic toxicity, It is disabled by epizootic disease office of the United Nations and WHO.Therefore, this field is badly in need of a kind of for treating the Chinese medicine of animal viral disease.

Clinically lack the apparent therapeutic agent of curative effect, the phenomenon that generally existing abuse of antibiotics.Brainstrust points out, in It is high and without side-effects to cure Chinese medicine curative effect in terms for the treatment of influenza, it is economical and practical.We have developed the present invention thus, try out in facing Bed, in the past few years we are treated, curative effect is clearly for flu, fever, the infection of the upper respiratory tract and virus infection with this medicine.

Summary of the invention

To solve the above problems, the present invention provides the veterinary Chinese medicine combinations for preventing and treating anemopyretic cold and viral influenza Object and preparation method thereof, specific as follows:

For preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza, it is made of the bulk pharmaceutical chemicals of following parts by weight: stone 150 ~ 300 parts of cream, 60 ~ 150 parts of rhizoma anemarrhenae, 60 ~ 150 parts of the root of Dahurain angelica, 100 ~ 200 parts of honeysuckle, 100 ~ 200 parts of wild chrysanthemum, Fructus Forsythiae 60 ~ 150 parts, 20 ~ 40 parts of Baical Skullcap root P.E, 60 ~ 150 parts of cape jasmine, 60 ~ 150 parts of Radix Isatidis, 120 ~ 300 parts of folium isatidis, oriental wormwood 100 ~ 200 parts, 100 ~ 200 parts of thick wood-fern rhizome, 100 ~ 200 parts of blackberry lily, 60 ~ 150 parts of dandelion, 60 ~ 150 parts of viola mandshurica, campanulaceae 60 ~ 150 parts, 2 ~ 6 parts of borneol, 2 ~ 6 parts of menthol.

It is made of the bulk pharmaceutical chemicals of following parts by weight: 160 parts of gypsum, 80 parts of rhizoma anemarrhenae, 100 parts of the root of Dahurain angelica, 150 parts of honeysuckle, open country 150 parts of chrysanthemum, 100 parts of Fructus Forsythiae, 20 parts of Baical Skullcap root P.E, 100 parts of cape jasmine, 100 parts of Radix Isatidis, 300 parts of folium isatidis, oriental wormwood 150 Part, 150 parts of thick wood-fern rhizome, 150 parts of blackberry lily, 100 parts of dandelion, 100 parts of viola mandshurica, 100 parts of campanulaceae, 5 parts of borneol, menthol 5 parts.

The Baical Skullcap root P.E is commercially available or artificial extraction.

The Baical Skullcap root P.E manually extracted is made by following Advanced methods: radix scutellariae slice adds water to cook three times, the One time 2 hours, each 1 hour of second and third time, collecting decoction, filtration, filtrate concentration, and addition 2mol/L hydrochloric acid is molten at 80 DEG C Liquid adjusts pH value to 1.0~2.0, keeps the temperature 1 hour, stands 12 hours, filtration, precipitating plus 6~8 times of amount water, with 40% hydroxide Sodium solution adjusts pH value to 7.0, then plus equivalent ethyl alcohol, be stirred to dissolve, filter, filtrate adjusts pH value with 2mol/L hydrochloric acid solution 30 minutes are kept the temperature to 2.0,60 DEG C, stands 12 hours, filtration, precipitating is washed till pH value 7.0 with ethyl alcohol, it is spare to wave most ethyl alcohol.

The quality accounting of scutelloside is not less than 85% in the Baical Skullcap root P.E manually extracted.

The dosage form of the Chinese medicine composition is Chinese medicine soluble powder or granule.

For preventing and treating the preparation method of the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza, preparation method is such as Under:

First by gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, oriental wormwood, thick wood-fern rhizome, Blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 30-60 minutes, and then heating boils extraction at least three times, are then combined with Decocting liquid, filtrate are concentrated into relative density 1.20 ~ 1.24, and 95% ethyl alcohol of equivalent is added, and stir, and stand, filtration, and recycling ethyl alcohol is dense Cream is received in contracting, and Baical Skullcap root P.E and sucrose is added or Baical Skullcap root P.E, sucrose and cyclodextrin mixt are pelletized, dry, sprays into borneol With the ethanol of menthol, 1000 parts of particles are made.

Preferably, first by gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, mattress Old, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 45 minutes, are then heated and are boiled extraction 3 times, and first Secondary 1 hour, second and third each 45 minutes collecting decoction was then combined with decocting liquid, filtrate is concentrated into relative density 1.20 ~ 1.24, adds Enter 95% ethyl alcohol of equivalent, stir, stand 12 hours, cream is received in filtration, recycling ethyl alcohol concentration, be added Baical Skullcap root P.E and sucrose or Baical Skullcap root P.E, sucrose and cyclodextrin mixt are pelletized, dry, are sprayed into the ethanol of borneol and menthol, are made 1000 parts Grain.

For preventing and treating the preparation method of the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza, by gypsum, rhizoma anemarrhenae, gold Honeysuckle flower, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, Campanulaceae is soaked in water 30-60 minutes, heating boil extraction at least three times, collecting decoction, filtrate be concentrated into relative density 1.20 ~ 1.24,95% ethyl alcohol of equivalent is added, stirs, stands, ethyl alcohol concentration is recycled in filtration, and spray drying crushes spare；Menthol is added With borneol, ethyl alcohol, Tween-80 heating dissolution is added, the stirring of cyclodextrin constant temperature is added, low-temperature reduced-pressure dry, pulverize spare；Then Baical Skullcap root P.E and sucrose is added or Baical Skullcap root P.E, sucrose and cyclodextrin are mixed and made into 1000 parts of soluble powders, dispenses, i.e., ?.

Preferably, by gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, oriental wormwood, silk floss Horse rhizome of cyrtomium, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 45 minutes, and extraction 3 times is boiled in heating, and 1 hour for the first time, the Two, each 45 minutes collecting decoctions, filtrate are concentrated into relative density 1.20 ~ 1.24 three times, and 95% ethyl alcohol of equivalent is added, and stir, and stand 12 hours, filtration, recycling ethyl alcohol concentration was spray-dried, crushes spare；Menthol and borneol is added, ethyl alcohol, Tween-80 is added The stirring of cyclodextrin constant temperature is added in heating dissolution, and low-temperature reduced-pressure dry, pulverize spare；Then be added Baical Skullcap root P.E and sucrose or Baical Skullcap root P.E, sucrose and cyclodextrin are mixed and made into 1000 parts of soluble powders, packing to get.

The effect of each bulk pharmaceutical chemicals of Chinese medicine composition of the invention, is summarized as follows:

Radix Isatidis: for the root of Cruciferae woaded blue platymiscium woaded blue；Containing indigo, indigo red and a variety of amino acid, as arginine, Glutamic acid etc., also containing plurality of active ingredients such as sinigrin, indigo glycosides, couroupitine As；Radix Isatidis is bitter in taste, trembles with fear, return heart, lung.Liver, Stomach meridian；Energy heat-clearing, removing toxic substances, cool blood, relieving sore-throat；Cure mainly anemopyretic cold, influenza, epidemic meningitis, encephalitis, major part pestilence, scarlet fever, individually Equal diseases；The modern pharmacology proves that Radix Isatidis has antibacterium, antiviral, antiendotoxin, anticancer and other effects, while to siberian crabapple System has adjustment effect.

Folium isatidis: for the leaf of Cruciferae woaded blue platymiscium woaded blue；Contain indigo, woaded blue glycosides, indigo red, rosasterol etc. Plurality of active ingredients；It is bitter in taste, it trembles with fear；Return heart, stomach, liver, lung channel；It can clearing heat and detoxicating, blood cooling and ecchymoses removing；It is tired to cure mainly warm heat disease high fever Yearningly, coma, macula are spitted blood, bleeding from five sense organs or subcutaneous tissue, jaundice, dysentery, erysipelas, sore throat, aphtha, mumps etc.；The modern pharmacology proves that folium isatidis Has the effects that resisting pathogenic microbes, antiendotoxin, anti-oxidant.

Honeysuckle: for Caprifoliaceae woodbine honeysuckle, Lonicera confusa, wild rice gland honeysuckle, fulvoushair honeysuckle flower bud；Contain Phenolic acid class such as chlorogenic acid, isochlorogenic acid, sterols such as cupreol, volatile oil such as linalool, ethyl palmitate, linolenic acid second Ester etc., the plurality of active ingredients such as flavonoids such as galuteolin, lonicerin, Hyperoside；Honeysuckle nature and flavor are sweet, tremble with fear；Return lung, stomach Through；It can be clearing heat and detoxicating；Cure mainly affection of exogenous wind-heat or warm disease heating, heatstroke, toxic-heat and blood stasis, carbuncle swells furunculosis, sore throat, multi-infection disease Disease etc.；The modern pharmacology proves that honeysuckle has resisting pathogenic microbes, antitoxin, anti-inflammatory, reducing blood lipid and other effects.

Fructus Forsythiae: for the fruit of Oleaceae forsythia Fructus Forsythiae；Contain lignin compound such as forsythin, forsythin Member, dextrorotation rosin powder etc., flavone compound such as rutin sophorin, vinylbenzene analog derivative such as Fructus Forsythiae rouge glycosides A, C, D, E, Fructus Forsythiae kind glycosides Deng, for example bright wooden glycosides of cyclohexyl alcohol derivatives, Fructus Forsythiae cyclohexanol etc., triterpene compound such as betulic acid, oleanolic acid etc., Also containing plurality of active ingredients such as furans list lactone compounds；Fructus Forsythiae is bitter in taste, slightly cold, return lung, the heart, gallbladder channel；Can it is clearing heat and detoxicating, Dispersing swelling and dissipating binds；Cure mainly anemopyretic cold, warm disease, heat gonorrhea renal shutdown, ulcer, pyogenic infections, scrofula, goiter, sore throat etc.；Modern pharmacology card It is bright, Fructus Forsythiae is spat with antimicrobial, anti-liver injury, inhibition phosphodiesterase and lipoxygenase and town and other effects.

Blackberry lily: for the rhizome of Iridaceae blackberry lily platymiscium blackberry lily；Root and rhizome contains osajin such as iris aglycone, iris Flavones, Tectoridin, Isoflavones Extracted from Belamcanda Chinensis etc., triterpenes components such as sheganone, Apocynin, belamcandal etc., also contain carrot The a variety of active ingredients such as glycosides, resveratrol, P-hydroxybenzoic acid, cupreol, dichotomitin；Nature and flavor bitter, acrid, cold, it is toxic, return Lung, Liver Channel；Energy clearing heat and detoxicating, dispelling phlegm and relieving sore-throat, dispersing blood stasis dissipating bind cure mainly abscess of throat, phlegm stops up cough and asthma, scrofula tuberculosis, carbuncle sore tumefacting virus Deng；The modern pharmacology proves that blackberry lily has the effects that anti-inflammatory, antiallergy, antimicrobial, eliminating the phlegm.

Wild chrysanthemum: bitter, pungent, cold nature, return lung, Liver Channel.Has the function of clearing heat and detoxicating, dispelling wind calming the liver.Cure mainly wind-heat Flu, furunculosis carbuncle swells, abscess of throat, wind-fire red eye, headache and dizziness etc..Containing volatile oil, robinin, flavonoids, sesquialter terpene lactone Class etc..

Oriental wormwood: removing dampness through diuresis and removing jaundice is used for jaundice；Modern times are usually used in acute and chronic viral icteric hepatitis, cirrhosis etc..

Cape jasmine: clearing heat and promoting diuresis, cooling blood and hemostasis.

Borneol (MEIHUA BINGPIAN): the native crystal being precipitated in the resin for Dipterocarpaceae Dipterocarpus plant borneo camphor tree Compound, ingredient are d-Bomeol；Nature and flavor are pungent, bitter, cool, enter the heart, lung channel；It can inducing resuscitation of having one's ideas straightened out, heat dissipation pain, shade removing；It is main Control apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm confusing heart, deafness with qi stagnation, conjunctivitis, sore throat, aphtha, carbuncle swells, hemorrhoid etc.；Modern pharmacology Learning proves that borneol has the effects that anti-inflammatory, antibacterial, antifertility.

Campanulaceae: for the root of Campanulaceae Platycodon grandiflouorum Platycodon grandiflouorum；Contain saponin(e such as platycodin A, C, D, D2, D3 etc., saponin(e First such as platycodigenin, polygalic acid, prosapogenin, a variety of active ingredients such as sterols such as hitodesterol；It is bitter in taste, pungent, flat, It attaches to the lung and stomach meridians；It can clearing lung and eliminating the phlegm, relieving sore throat and evacuating pus；Cure mainly coughing with a lot of sputum, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery abdomen Pain etc.；The modern pharmacology proves that campanulaceae have eliminating the phlegm, antibechic, anti-inflammatory, antiulcer, hypoglycemic and other effects, to cardiovascular system, in Pivot nervous system has adjustment effect.

Radix scutellariae: cold in nature, bitter, return lung, gallbladder, spleen, large intestine, small intestinl channel；With heat-clearing and damp-drying drug, purging fire for removing toxin, arresting bleeding and miscarriage prevention The effect of.This product have broad-spectrum antibacterial action, to alpha streptococcus, pneumococcus, diplococcus meningitidis, staphylococcus aureus, Corynebacterium diphtheriae, comma bacillus, shigella dysenteriae, three type brucella of cattle and sheep pig, Pseudomonas aeruginosa, white scour of chicken bacillus etc. have antibacterial Effect, it is especially stronger to staphylococcus and Pseudomonas aeruginosa inhibiting effect.Also there is inhibiting effect to certain pathogenic fungus, virus, Also there is inhibitory or killing effect to Leptospira, protozoon etc..For enteritis, pneumonia, brucellosis, influenza, endometritis, conjunctiva Scorching, ophthalmia and inflammation are swollen etc..Also the prevention that can make the white scour of chicken is medicinal

Dandelion: clearing heat and detoxicating, dampness removing.Cure mainly heat toxin sore carbuncle, acute mastitis, acute appendicitis etc..Clinic is mostly used its compound prescription decoctum, antiviral work With antibacterial action that is definite, and having certain.Boil carbuncle swells are treated, are applied alone i.e. effectively.There is clinical road, dandelion is treating chronic gallbladder When capsulitis, acute icterohepatitis, effect is remarkably promoted for the recovery of liver function and icterus index, and can treat stomach Scorching, ecphyaditis and digestive tract ulcer.

Gypsum: clearing heat-fire promotes the production of body fluid to quench thirst.Cure mainly fever caused by exogenous pathogenic factors, lung heat syndrome characterized by dyspnea, the greedy drink of stomach energy, high fever coma, it is manic not Peace.

Rhizoma anemarrhenae: nourishing yin and lessening fire, moisturizing dryness and lubricating intestine.It controls dysphoria with smothery sensation to quench one's thirst, hectic fever due to yin labor heat, cough with lung heat, dry feces, urine is not Benefit.For warm heat disease, the lungs stomach excess heat symptom-complex such as the high Sheng of heat symptoms caused by an exopathgen, high fever, polydipsia, large and bounding pulse.Rhizoma anemarrhenae plays the role of clearing heat-fire relieving restlessness. For cough with lung heat or dry cough due to yin deficiency, the phlegm card such as thick.This product has the benefits of clear purte the white, nourishing Yin and moistening lung.For fire excess from yin deficiency, lung kidney Joint caused by thanks to steams the diseases such as hectic fever, night sweat, vexed.Rhizoma anemarrhenae plays the role of nourishing yin and lessening fire.It can be used for the deficiency of Yin to quench one's thirst symptoms include mouth Yearningly, more, the more persons of urine are drunk.This product has enriching yin to moisten, and bath, promote the production of body fluid to quench thirst effect.Clearing heat-fire: being used for hyperpyrexia polydipsia, often matches gypsum； For cough with lung heat, often match fritillaria.Nourishing yin and lessening fire: Cortex Phellodendri, glutinous rehmannia are often matched in fever, night sweat for the deficiency of Yin.

The root of Dahurain angelica: wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving.For having a headache, having a toothache, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, carbuncle Subcutaneous ulcer sore, pruitus.

Thick wood-fern rhizome: clearing heat and detoxicating, hemostasis, desinsection.Epidemic disease flu, headache due to pathogenic wind-heat, febrile virulent maculae, sore swollen toxin, metrorrhagia and metrostaxis Lower blood, abdominal pain due to enterositosis.

Viola mandshurica: taste bitter, acrid, cold.Distributed in heart and lung channels.With clearing heat and detoxicating, cool blood detumescence, the effect of clearing heat and promoting diuresis is main Control furunculosis, carbuncle swells, scrofula, jaundice, dysentery, diarrhea, hot eyes, sore throat, venomous snake bite.

Menthol: wind-dispelling heat-dissipating, head clearing, relieving sore-throat, promoting eruption.Cure mainly affection of exogenous wind-heat, abscess of throat, hot eyes, rubeola.

Beneficial effects of the present invention:

The present invention uses gypsum, rhizoma anemarrhenae, the root of Dahurain angelica, honeysuckle, wild chrysanthemum, Fructus Forsythiae, Baical Skullcap root P.E, cape jasmine, Radix Isatidis, smalt Leaf, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae, borneol, menthol totally 18 taste pure natural Chinese herbal medicine, according to Monarch principle composition of prescription, with " righting, eliminating evil, promoting blood circulation, dysmenorrhea are active " principle cube.

Gypsum compatibility rhizoma anemarrhenae is monarch drug in a prescription in side, follows the example of Baihu Tang heat-clearing and protects saliva relieving restlessness；Honeysuckle, Fructus Forsythiae, Radix Isatidis, smalt Leaf, wild chrysanthemum, dandelion, viola mandshurica, thick wood-fern rhizome are antipyretic and detoxicated, relieving exterior-interior syndrome, imitate altogether it is favourable, be side in ministerial drug；Cape jasmine Son, radix scutellariae, oriental wormwood clearing interior heat, removing pattogenic heat from the blood and toxic material from the body, blackberry lily is clearing heat and detoxicating, relieving sore-throat resolving sputum, heat dissipation detumescence；Campanulaceae promoting the dispersing function of the lung, relieving sore-throat are dispelled Phlegm is altogether adjutant；The pungent perfume of the root of Dahurain angelica, borneol, menthol is sensible, dirty scattered heresy is warded off, to make medicine；It is mainly used for treating livestock and poultry anemopyretic cold And the diseases such as influenza caused by virus have good therapeutic effect, rapidly, easy to use, clinical value is high for effect.

Specific embodiment

Only invention is further described in detail for following embodiments, but does not constitute any limitation of the invention.

Embodiment 1

Preferably, it is made of the bulk pharmaceutical chemicals of following parts by weight: 160 parts of gypsum, 80 parts of rhizoma anemarrhenae, 100 parts of the root of Dahurain angelica, honeysuckle 150 parts, 150 parts of wild chrysanthemum, 100 parts of Fructus Forsythiae, 20 parts of Baical Skullcap root P.E, 100 parts of cape jasmine, 100 parts of Radix Isatidis, 300 parts of folium isatidis, 150 parts of oriental wormwood, 150 parts of thick wood-fern rhizome, 150 parts of blackberry lily, 100 parts of dandelion, 100 parts of viola mandshurica, 100 parts of campanulaceae, borneol 5 Part, 5 parts of menthol.

Further, the Baical Skullcap root P.E is commercially available or artificial extraction.

Further, the Baical Skullcap root P.E manually extracted is made by following Advanced methods: radix scutellariae slice adds decocting It boils three times, 2 hours for the first time, each 1 hour of second and third time, collecting decoction, filtration, filtrate concentration, and is added at 80 DEG C 2mol/L hydrochloric acid solution adjusts pH value to 1.0~2.0, keeps the temperature 1 hour, stands 12 hours, filtration, precipitating plus 6~8 times of amounts Water adjusts pH value to 7.0 with 40% sodium hydroxide solution, then plus equivalent ethyl alcohol, be stirred to dissolve, filter, filtrate 2mol/L salt Acid solution adjusts pH value and keeps the temperature 30 minutes to 2.0,60 DEG C, stands 12 hours, filtration, precipitating is washed till pH value 7.0 with ethyl alcohol, waves to the greatest extent Ethyl alcohol is spare.

Further, the content of scutelloside is not less than 85% in the Baical Skullcap root P.E.

Further, the dosage form of the Chinese medicine composition is Chinese medicine soluble powder or granule.

The preparation method of the above-mentioned veterinary Chinese medicinal composition for being used to prevent and treat anemopyretic cold and viral influenza, preparation method It is as follows:

First by gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, oriental wormwood, thick wood-fern rhizome, Blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 30-60 minutes, and then heating boils extraction at least three times, are then combined with Decocting liquid, filtrate are concentrated into relative density 1.20 ~ 1.24, and 95% ethyl alcohol of equivalent is added, and stir, and stand, filtration, and recycling ethyl alcohol is dense Cream is received in contracting, and Baical Skullcap root P.E and sucrose is added or Baical Skullcap root P.E, sucrose and cyclodextrin mixt are pelletized, dry, sprays into borneol With the ethanol of menthol, 1000 parts of particles are made.The concentration of menthol is 1-10% in the ethanol of menthol in the present invention, Parameter in other pelletizations does not influence effect of the invention, details are not described herein according to conventional parameter.

The preparation method of the above-mentioned veterinary Chinese medicinal composition for being used to prevent and treat anemopyretic cold and viral influenza, by gypsum, knows It is mother, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, pale reddish brown Chinese violet, campanulaceae are soaked in water 30-60 minutes, and heating boils extraction at least three times, and collecting decoction, filtrate is concentrated into relative density 1.20 ~ 1.24,95% ethyl alcohol of equivalent is added, stirs, stands, ethyl alcohol concentration is recycled in filtration, and spray drying crushes spare；It is added Menthol and borneol are added ethyl alcohol, Tween-80 heating dissolution, the stirring of cyclodextrin constant temperature are added, low-temperature reduced-pressure dry, pulverize standby With；Then Baical Skullcap root P.E and sucrose is added or Baical Skullcap root P.E, sucrose and cyclodextrin is mixed and made into 1000 parts of soluble powders, point Dress to get.

Embodiment 2

For preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza in the present embodiment, by the raw material of following parts by weight Medicine composition: 150 parts of gypsum, 60 parts of rhizoma anemarrhenae, 60 parts of the root of Dahurain angelica, 100 parts of honeysuckle, 100 parts of wild chrysanthemum, 60 parts of Fructus Forsythiae, radix scutellariae extract 20 parts of object, 60 parts of cape jasmine, 60 parts of Radix Isatidis, 120 parts of folium isatidis, 100 parts of oriental wormwood, 100 parts of thick wood-fern rhizome, 100 parts of blackberry lily, Pu Gong 60 parts of English, 60 parts of viola mandshurica, 60 parts of campanulaceae, 2 parts of borneol, 2 parts of menthol.

The Baical Skullcap root P.E is commercial product, and producer is Xi'an Rayleigh Biotechnology Co., Ltd, and the present invention is with this factory The product of family is tested, naturally it is also possible to be the product of other producers.

It is prepared the following steps are included: gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, smalt Leaf, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 60 minutes, are heated and are boiled extraction 3 times, and first Secondary 1 hour, second and third each 45 minutes collecting decoction, filtrate was concentrated into relative density 1.20 ~ 1.24, and 95% second of equivalent is added Alcohol, stirring stand 12 hours, filtration, and recycling ethyl alcohol concentration, spray drying crushes spare.Menthol and borneol, be added ethyl alcohol, Tween-80 heating dissolution, is added the stirring of cyclodextrin constant temperature, and low-temperature reduced-pressure is dry.It crushes spare.Baical Skullcap root P.E and sucrose is added 1000 parts of soluble powders are made, are dispensed with 200g/ bags.

Usage and dosage: usage and dosage: every 1L water, chicken, 2g are used in conjunction 3 ~ 5.

Embodiment 3

For preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza in the present embodiment, by the raw material of following parts by weight Medicine composition: 160 parts of gypsum, 80 parts of rhizoma anemarrhenae, 100 parts of the root of Dahurain angelica, 150 parts of honeysuckle, 150 parts of wild chrysanthemum, 100 parts of Fructus Forsythiae, radix scutellariae mention Take 20 parts of object, 100 parts of cape jasmine, 100 parts of Radix Isatidis, 300 parts of folium isatidis, 150 parts of oriental wormwood, 150 parts of thick wood-fern rhizome, 150 parts of blackberry lily, 100 parts of dandelion, 100 parts of viola mandshurica, 100 parts of campanulaceae, 5 parts of borneol, 5 parts of menthol.

The Baical Skullcap root P.E is artificial extraction, extracting method are as follows: radix scutellariae slice adds water to cook three times, and 2 is small for the first time When, each 1 hour of second and third time, collecting decoction, filtration, filtrate concentration, and 2mol/L hydrochloric acid solution is added to adjust at 80 DEG C PH value keeps the temperature 1 hour, stands 12 hours, filtration, precipitating adds 6~8 times of amount water, with 40% sodium hydroxide solution tune to 1.0~2.0 PH value is saved to 7.0, then plus equivalent ethyl alcohol, be stirred to dissolve, filter, filtrate adjusts pH value to 2.0,60 with 2mol/L hydrochloric acid solution DEG C heat preservation 30 minutes, 12 hours are stood, filtration, precipitating is washed till pH value 7.0 with ethyl alcohol, it is spare to wave most ethyl alcohol.

The content of scutelloside is not less than 85% in the Baical Skullcap root P.E manually extracted.

It is prepared the following steps are included: gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, smalt Leaf, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica are soaked in water 45 minutes, and extraction 3 times is boiled in heating, and 1 is small for the first time When, second and third each 45 minutes collecting decoction, filtrate is concentrated into relative density 1.20 ~ 1.24, and 95% ethyl alcohol of equivalent is added, stirs It mixes, stands 12 hours, filtration, recycling ethyl alcohol concentration is spray-dried, crushes spare.Ethyl alcohol, tween-is added in menthol and borneol 80 heating dissolutions, are added the stirring of cyclodextrin constant temperature, and low-temperature reduced-pressure is dry.It crushes spare.Baical Skullcap root P.E, sucrose and ring is added to paste Essence is mixed and made into 1000 parts of soluble powders, is dispensed with 200g/ bags.

Embodiment 4

For preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza in the present embodiment, by the raw material of following parts by weight Medicine composition: 300 parts of gypsum, 150 parts of rhizoma anemarrhenae, 150 parts of the root of Dahurain angelica, 180 parts of honeysuckle, 180 parts of wild chrysanthemum, 80 parts of Fructus Forsythiae, radix scutellariae mention Take 40 parts of object, 70 parts of cape jasmine, 130 parts of Radix Isatidis, 180 parts of folium isatidis, 120 parts of oriental wormwood, 200 parts of thick wood-fern rhizome, 200 parts of blackberry lily, 150 parts of dandelion, 80 parts of viola mandshurica, 150 parts of campanulaceae, 4 parts of borneol, 4 parts of menthol.

The Baical Skullcap root P.E is product, and producer is Xi'an Rayleigh Biotechnology Co., Ltd.

It is prepared the following steps are included: gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, smalt Leaf, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica are soaked in water 30 minutes, and extraction 3 times is boiled in heating, and 1 is small for the first time When, second and third each 45 minutes collecting decoction, filtrate is concentrated into relative density 1.20 ~ 1.24, and 95% ethyl alcohol of equivalent is added, stirs It mixes, stands 12 hours, filtration, recycling ethyl alcohol concentration is spray-dried, crushes spare.Ethyl alcohol, tween-is added in menthol and borneol 80 heating dissolutions, are added the stirring of cyclodextrin constant temperature, and low-temperature reduced-pressure is dry.It crushes spare.Baical Skullcap root P.E and sucrose or Huang is added A kind of reed mentioned in ancient books extract, sucrose and cyclodextrin are mixed and made into 1000 parts of soluble powders, are dispensed with 200g/ bags.

Embodiment 5

For preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza in the present embodiment, by the raw material of following parts by weight Medicine composition: 180 parts of gypsum, 100 parts of rhizoma anemarrhenae, 150 parts of the root of Dahurain angelica, 200 parts of honeysuckle, 120 parts of wild chrysanthemum, 150 parts of Fructus Forsythiae, radix scutellariae mention Take 30 parts of object, 130 parts of cape jasmine, 150 parts of Radix Isatidis, 200 parts of folium isatidis, 200 parts of oriental wormwood, 180 parts of thick wood-fern rhizome, 180 parts of blackberry lily, 120 parts of dandelion, 130 parts of viola mandshurica, 120 parts of campanulaceae, 3 parts of borneol, 3 parts of menthol.

The Baical Skullcap root P.E is artificial extraction, extracting method are as follows: radix scutellariae slice adds water to cook three times, and 2 is small for the first time When, each 1 hour of second and third time, collecting decoction, filtration, filtrate concentration, and 2mol/L hydrochloric acid solution is added to adjust at 80 DEG C PH value keeps the temperature 1 hour, stands 12 hours, filtration, precipitating adds 6~8 times of amount water, with 40% sodium hydroxide solution tune to 1.0~2.0 PH value is saved to 7.0, then plus equivalent ethyl alcohol, be stirred to dissolve, filter, filtrate adjusts pH value to 2.0,60 with 2mol/L hydrochloric acid solution DEG C heat preservation 45 minutes, 12 hours are stood, filtration, precipitating is washed till pH value 7.0 with ethyl alcohol, it is spare to wave most ethyl alcohol.

Embodiment 6

For preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza in the present embodiment, by the raw material of following parts by weight Medicine composition: 200 parts of gypsum, 120 parts of rhizoma anemarrhenae, 130 parts of the root of Dahurain angelica, 120 parts of honeysuckle, 200 parts of wild chrysanthemum, 120 parts of Fructus Forsythiae, radix scutellariae mention Take 35 parts of object, 150 parts of cape jasmine, 80 parts of Radix Isatidis, 260 parts of folium isatidis, 180 parts of oriental wormwood, 120 parts of thick wood-fern rhizome, 130 parts of blackberry lily, 80 parts of dandelion, 150 parts of viola mandshurica, 70 parts of campanulaceae, 5 parts of borneol, 5 parts of menthol.

It is prepared the following steps are included: first that gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, plate is blue Root, folium isatidis, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 50 minutes, and then heating is boiled It extracts 3 times, 1 hour for the first time, second and third each 45 minutes collecting decoction is then combined with decocting liquid, filtrate is concentrated into relative density 1.20 ~ 1.24,95% ethyl alcohol of equivalent is added, stirs, stands 12 hours, filtration, recycling ethyl alcohol concentration receives cream, radix scutellariae is added and mentions Object and sucrose or Baical Skullcap root P.E, sucrose and cyclodextrin mixt is taken to pelletize, it is dry, the ethanol of borneol and menthol is sprayed into, 1000 parts of particles are made.The concentration of menthol is 5% in the ethanol of menthol in the present embodiment.

Embodiment 7

For preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza in the present embodiment, by the raw material of following parts by weight Medicine composition: 240 parts of gypsum, 140 parts of rhizoma anemarrhenae, 80 parts of the root of Dahurain angelica, 190 parts of honeysuckle, 160 parts of wild chrysanthemum, 130 parts of Fructus Forsythiae, radix scutellariae mention Take 25 parts of object, 85 parts of cape jasmine, 120 parts of Radix Isatidis, 230 parts of folium isatidis, 160 parts of oriental wormwood, 140 parts of thick wood-fern rhizome, 190 parts of blackberry lily, 140 parts of dandelion, 90 parts of viola mandshurica, 90 parts of campanulaceae, 4 parts of borneol, 5 parts of menthol.

The Baical Skullcap root P.E is commercial product, and producer is Xi'an Rayleigh Biotechnology Co., Ltd.

It is prepared the following steps are included: first that gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, plate is blue Root, folium isatidis, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 50 minutes, and then heating is boiled It extracts 3 times, 1 hour for the first time, second and third each 45 minutes collecting decoction is then combined with decocting liquid, filtrate is concentrated into relative density 1.20 ~ 1.24,95% ethyl alcohol of equivalent is added, stirs, stands 12 hours, filtration, recycling ethyl alcohol concentration receives cream, radix scutellariae is added and mentions Object and sucrose or Baical Skullcap root P.E, sucrose and cyclodextrin mixt is taken to pelletize, it is dry, the ethanol of borneol and menthol is sprayed into, 1000 parts of particles are made.The concentration of menthol is 1% in the ethanol of menthol in the present embodiment.

Embodiment 8

It is prepared the following steps are included: first that gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, plate is blue Root, folium isatidis, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 50 minutes, and then heating is boiled It extracts 3 times, 1 hour for the first time, second and third each 45 minutes collecting decoction is then combined with decocting liquid, filtrate is concentrated into relative density 1.20 ~ 1.24,95% ethyl alcohol of equivalent is added, stirs, stands 12 hours, filtration, recycling ethyl alcohol concentration receives cream, radix scutellariae is added and mentions Object and sucrose or Baical Skullcap root P.E, sucrose and cyclodextrin mixt is taken to pelletize, it is dry, the ethanol of borneol and menthol is sprayed into, 1000 parts of particles are made.The concentration of menthol is 3% in the ethanol of menthol in the present embodiment.

Embodiment 9

It is prepared the following steps are included: first that gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, plate is blue Root, folium isatidis, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 50 minutes, and then heating is boiled It extracts 3 times, 1 hour for the first time, second and third each 45 minutes collecting decoction is then combined with decocting liquid, filtrate is concentrated into relative density 1.20 ~ 1.24,95% ethyl alcohol of equivalent is added, stirs, stands 12 hours, filtration, recycling ethyl alcohol concentration receives cream, radix scutellariae is added and mentions Object and sucrose or Baical Skullcap root P.E, sucrose and cyclodextrin mixt is taken to pelletize, it is dry, the ethanol of borneol and menthol is sprayed into, 1000 parts of particles are made.The concentration of menthol is 8% in the ethanol of menthol in the present embodiment.

Embodiment 10

It is prepared the following steps are included: first that gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, plate is blue Root, folium isatidis, oriental wormwood, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 50 minutes, and then heating is boiled It extracts 3 times, 1 hour for the first time, second and third each 45 minutes collecting decoction is then combined with decocting liquid, filtrate is concentrated into relative density 1.20 ~ 1.24,95% ethyl alcohol of equivalent is added, stirs, stands 12 hours, filtration, recycling ethyl alcohol concentration receives cream, radix scutellariae is added and mentions Object and sucrose or Baical Skullcap root P.E, sucrose and cyclodextrin mixt is taken to pelletize, it is dry, the ethanol of borneol and menthol is sprayed into, 1000 parts of particles are made.The concentration of menthol is 10% in the ethanol of menthol in the present embodiment.

Test example 1: powder prepared by above-described embodiment 2~4 is used to treat the clinical verification of Bird Flu

Experimental animal: the main feature of Bird Flu disease: dotted to break out, small area is popular, easy to recur, 6~14d of the course of disease, Disease incidence 100%, peak mortality was at the 2nd~4 day after the onset, the death rate 1%~6%, high up to 20% or more, laying rate decline 10%~60%, the complete halt production having, 5%~10% chicken produces lopsided egg and soft-shelled egg, most of eggshell color are thin out.Diseased chicken spirit Depressed, few food or food refusal are closed one's eyes, and hat and wattle black, head swelling, and shin is dry, general red, draw yellow, green, white loose stool, Expiratory dyspnea, mouth, nose flow out volume mucus, shake the head, and some chicken heads are backward or side is reversed.Bleeding concentrates on glandular stomach, muscular stomach angle There is ecchymosis with duodenum, hydropericardium, intracardiac outer membrane under matter layer, differ in size, popularity is congested under scalp.Ovary and defeated Oviduct bleeding or hyperemia, tube wall swelling, yolk rupture, the faint yellow yolk liquid of volume is gathered in abdominal cavity.There are about 1%~10% chickens after being ill It does not lay eggs throughout one's life, some is up to 20%.80%~90% chicken group secondary ehec infection or salmonella etc. after this disease is broken out Disease is adopted pathological material of disease and is chemically examined at me, tested through AGP, HI, Bacteria Culture, virus purification combination clinical symptoms, pathology dissect are made a definite diagnosis For bird flu H9 hypotype.From be diagnosed as in chicken house chicken group according to clinical symptoms and epidemiology in the chicken group of Bird Flu with Machine chooses 500, is divided into 5 groups.

Trial drug: test group 1~3 successively applies the soluble powder of the preparation of embodiment 2~4, and every 1L water, chicken, 2g is used in conjunction 5 days；Positive controls 1 apply commercially available amantadine, and daily every 1kg chicken weight medication 25mg mixes drink, is used in conjunction 5 days；Blank control Group is not administered.

Test method: said medicine is used in conjunction 5 days, observe curative effect and count the healing of application 3 days and 5 days, improvement, it is effective, Invalid and dead number of elements, calculates total effective rate, and test result is detailed in the following table 1.

Curative effect determinate standard:

Cure: after medication, clinical symptoms disappear, and pathology dissect is without obvious lesion；Laying rate of laying hen restores level before illness.Feeding Amount, amount of drinking water, mental restoration are normal；

Improve: after medication, clinical symptoms disappear substantially, feed intake, amount of drinking water, spiritual normal, laying rate of laying hen and egg matter Amount is significantly along liter；

Effective: after medication, clinical symptoms are obviously improved, feed intake and the significant improvement of spirit, and the quality of laying hen egg yield and egg has Improved；

Invalid: clinical symptoms, feed intake, amount of drinking water, spirit and production performance do not improve before and after medication, or even are aggravated to dislike Change or dead.

The therapeutic effect of each test group of table 1

Exercising result of the table 2 to laying rate of laying hen

As shown in Table 1, medication 3 days, the total effective rate of test group 1~3 is up to 89% or more；Medication 5 days, total effective rate up to 92 or more, Statistical analysis shows that the total effective rate of test group 1~3 is significantly higher than positive controls and blank control group (P < 0.01), between group Without significant difference (P > 0.05), but between cure rate test group on have significant difference (P < 0.01).

Harm of the bird flu to laying hen is mainly manifested in being decreased obviously for laying rate in addition to respiratory symptom, egg it is different Normal rate increases, and 3 ~ 5 days egg productions are decreased obviously after illness, and laying rate can drop to 10% from 95%, some almost halt productions.From table 2 In as can be seen that not significant (P > 0.05) with the laying rate difference of test group 1~3 during being administered after illness before illness, but with it is right Compare according to the laying rate of group, difference is extremely significant (P < 0.01), table 2 the result shows that, the present invention resists fowl to diseased chicken of laying eggs Influenza, the good influence for preventing egg production from declining.

Test example 2: powder prepared by embodiment 3 is used to treat the clinical expanding test of Bird Flu

Powder prepared with embodiment 3 is adopted, clinical expanding test, usage and dosage are carried out to certain chicken farm in Zhengzhou, Luohe, Kaifeng Are as follows: mixed feeding, every 100kg feed mix medicine 1kg, are freely eaten, are used in conjunction 3~5 days.Its statistical result is as follows:

The clinical expanding test statistical result of table 3

	Diseased chicken number/only	Cure/only	In vain/only	Total effective rate/%
					Zhengzhou	1000	520	52	94.8
Luohe	1000	560	45	95.5
					Kaifeng	1000	538	48	95.2

By the clinical expanding test of table 3 it is found that of the invention is curative for effect, cure rate is higher.We use 3 times of agent of usual amounts Amount, is added in feed, observes its toxicity, as a result have no that chicken has any exception, illustrate that the safety coefficient of the drug is larger, toxicity Act on very little.

Typical case is reported as follows:

1, Zhengzhou farm, more than 1300 plumage of 27 age in days Sanhuang broiler, from illness to medical more than 60 plumage of dead, according to epidemic disease Learn, clinical symptoms and chicken dissect of dying of illness are as a result, be diagnosed as Bird Flu, prepare powder mixed feeding 3 days of application embodiment 2, Death stops, and feeding, drinking-water, spirit, growth recovery are normal.

2, Luohe farm, more than 1400 plumage of 300 age in days, three yellow race chicken, 210 age in days, three yellow race chicken, 4600 plumage, from illness to Medical, death toll reaches over one hundred, and laying rate is down to 14% by 60%.It adopts pathological material of disease to be chemically examined at me, be tested through AGP, HI, bacterium training It supports, virus purification combination clinical symptoms, pathology dissect are diagnosed as bird flu H9 hypotype Bird Flu.Mixed drink 5 days, death stops Only, 3 days after medication, laying rate rises to 35%, 15 days after medication, diseased chicken whole rehabilitation, before laying rate is restored to disease It is horizontal.

Claims

1. the veterinary Chinese medicinal composition for preventing and treating anemopyretic cold and viral influenza, it is characterised in that: by following parts by weight Bulk pharmaceutical chemicals composition: 150 ~ 300 parts of gypsum, 60 ~ 150 parts of rhizoma anemarrhenae, 60 ~ 150 parts of the root of Dahurain angelica, 100 ~ 200 parts of honeysuckle, wild chrysanthemum 100 ~ 200 parts, 60 ~ 150 parts of Fructus Forsythiae, 20 ~ 40 parts of Baical Skullcap root P.E, 60 ~ 150 parts of cape jasmine, 60 ~ 150 parts of Radix Isatidis, folium isatidis 120 ~ 300 parts, 100 ~ 200 parts of oriental wormwood, 100 ~ 200 parts of thick wood-fern rhizome, 100 ~ 200 parts of blackberry lily, 60 ~ 150 parts of dandelion, viola mandshurica 60 ~ 150 parts, 60 ~ 150 parts of campanulaceae, 2 ~ 6 parts of borneol, 2 ~ 6 parts of menthol.

2. according to claim 1 for preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza, feature It is: is made of the bulk pharmaceutical chemicals of following parts by weight: 160 parts of gypsum, 80 parts of rhizoma anemarrhenae, 100 parts of the root of Dahurain angelica, 150 parts of honeysuckle, wild chrysanthemum 150 parts, 100 parts of Fructus Forsythiae, 20 parts of Baical Skullcap root P.E, 100 parts of cape jasmine, 100 parts of Radix Isatidis, 300 parts of folium isatidis, 150 parts of oriental wormwood, silk floss 150 parts of horse rhizome of cyrtomium, 150 parts of blackberry lily, 100 parts of dandelion, 100 parts of viola mandshurica, 100 parts of campanulaceae, 5 parts of borneol, 5 parts of menthol.

3. according to claim 1 for preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza, feature Be: the Baical Skullcap root P.E is commercially available or artificial extraction.

4. according to claim 3 for preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza, feature Be: the Baical Skullcap root P.E manually extracted is made by following Advanced methods: radix scutellariae slice adds water to cook three times, first Secondary 2 hours, each 1 hour of second and third time, collecting decoction, filtration, filtrate concentration, and 2mol/L hydrochloric acid solution is added at 80 DEG C PH value is adjusted to 1.0~2.0,1 hour is kept the temperature, stands 12 hours, filtration, precipitating plus 6~8 times of amount water, with 40% sodium hydroxide Solution adjusts pH value to 7.0, then plus equivalent ethyl alcohol, be stirred to dissolve, filter, filtrate with 2mol/L hydrochloric acid solution adjust pH value to 2.0,60 DEG C keep the temperature 30 minutes, stand 12 hours, and filtration, precipitating is washed till pH value 7.0 with ethyl alcohol, it is spare to wave most ethyl alcohol.

5. it is according to claim 3 or 4 for preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza, it is special Sign is: the quality accounting of scutelloside is not less than 85% in the Baical Skullcap root P.E manually extracted.

6. the veterinary Chinese medicine combination according to claim 1-4 for preventing and treating anemopyretic cold and viral influenza Object, it is characterised in that: the dosage form of the Chinese medicine composition is Chinese medicine soluble powder or granule.

7. according to claim 1-5 for preventing and treating the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza Preparation method, it is characterised in that: preparation method is as follows:

8. according to claim 7 for preventing and treating the preparation side of the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza Method, it is characterised in that:

First by gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, oriental wormwood, thick wood-fern rhizome, Blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 45 minutes, and then extraction 3 times is boiled in heating, and 1 hour for the first time, second, Each 45 minutes collecting decoctions three times, are then combined with decocting liquid, and filtrate is concentrated into relative density 1.20 ~ 1.24, and 95% second of equivalent is added Alcohol, stirring stand 12 hours, filtration, and recycling ethyl alcohol concentration receives cream, Baical Skullcap root P.E and sucrose or Baical Skullcap root P.E, sugarcane is added Sugar is pelletized with cyclodextrin mixt, dry, sprays into the ethanol of borneol and menthol, 1000 parts of particles are made.

9. according to claim 1 or 4 for preventing and treating the system of the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza Preparation Method, it is characterised in that: by gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, mattress Old, thick wood-fern rhizome, blackberry lily, dandelion, viola mandshurica, campanulaceae are soaked in water 30-60 minutes, and heating boils extraction at least three times, Collecting decoction, filtrate are concentrated into relative density 1.20 ~ 1.24, and 95% ethyl alcohol of equivalent is added, and stir, and stand, and ethyl alcohol is recycled in filtration Concentration, spray drying crush spare；Menthol and borneol is added, ethyl alcohol, Tween-80 heating dissolution is added, it is permanent that cyclodextrin is added Temperature stirring, low-temperature reduced-pressure dry, pulverize spare；Then Baical Skullcap root P.E and sucrose is added or Baical Skullcap root P.E, sucrose and ring are pasted Essence is mixed and made into 1000 parts of soluble powders, packing to get.

10. according to claim 9 for preventing and treating the preparation of the veterinary Chinese medicinal composition of anemopyretic cold and viral influenza Method, it is characterised in that:

By gypsum, rhizoma anemarrhenae, honeysuckle, wild chrysanthemum, Fructus Forsythiae, the root of Dahurain angelica, cape jasmine, Radix Isatidis, folium isatidis, oriental wormwood, thick wood-fern rhizome, penetrate Dry, dandelion, viola mandshurica, campanulaceae are soaked in water 45 minutes, and extraction 3 times is boiled in heating, and 1 hour for the first time, second and third time each 45 minutes collecting decoctions, filtrate are concentrated into relative density 1.20 ~ 1.24, and 95% ethyl alcohol of equivalent is added, and stirring stands 12 hours, filter It crosses, recycling ethyl alcohol concentration, spray drying crushes spare；Menthol and borneol is added, ethyl alcohol, Tween-80 heating dissolution is added, The stirring of cyclodextrin constant temperature is added, low-temperature reduced-pressure dry, pulverize spare；Then Baical Skullcap root P.E and sucrose is added or radix scutellariae extracts Object, sucrose and cyclodextrin are mixed and made into 1000 parts of soluble powders, packing to get.