CN108378958B

CN108378958B - Artificial blood vessel

Info

Publication number: CN108378958B
Application number: CN201710775473.2A
Authority: CN
Inventors: 李潮
Original assignee: Beijing Yuhengjia Technology Co ltd
Current assignee: Beijing Yuhengjia Technology Co ltd
Priority date: 2017-08-31
Filing date: 2017-08-31
Publication date: 2024-02-02
Anticipated expiration: 2037-08-31
Also published as: CN108378958A

Abstract

The invention discloses an artificial blood vessel, which comprises a body and at least one group of grid sheets; the body is provided with at least one porous part, and the porous part is formed by arranging a plurality of through holes on part of the surface of the body; the grid sheets are arranged on the outer surface of the body, and each group of grid sheets corresponds to each porous part respectively; each group of grid plates comprises at least one grid plate, and each grid plate is provided with a base edge so as to be connected to the position of the body close to the porous part, so that the grid plates can cover the porous part in an openable and closable manner. According to the invention, the opening part is formed on the body, and the grid sheet is arranged on the outer surface of the body to cover the opening part in an openable and closable manner, so that the controllable use of the artificial blood vessel windowing structure is realized. Compared with the existing artificial blood vessel, the invention can overcome the problem of deviation of windowing, and simultaneously, the effectiveness of the artificial blood vessel closure is ensured.

Description

Artificial blood vessel

Technical Field

The invention relates to the technical field of artificial blood vessels, in particular to an artificial blood vessel with a porous structure.

Background

At present, in the treatment of arterial diseases, especially for lesions such as aneurysms, arterial interlayers and the like, an arterial cavity interventional method is often adopted for treatment, and the isolation of the artificial blood vessel to the arterial lesion part is realized by sending the artificial blood vessel into and covering the arterial lesion part, so that the non-physiological blood flow caused by the lesions is eliminated.

However, for lesions that occur, for example, in the vicinity of arterial branches, the vascular prosthesis may cause occlusion of the blood flow of the occluded branch artery while isolating the lesion, which in turn causes ischemia of the supply area of the branch arterial vessel. In order to solve the technical problems, a person skilled in the art adopts a windowed structural design for the artificial blood vessel. The window-opening design of the existing artificial blood vessel mainly comprises a pre-opening window type and a flood hole window type.

In the case of a pre-fenestration type vascular prosthesis, the pre-fenestration of the same size as the target artery opening is pre-made before the vascular prosthesis is used, and there is a risk of misalignment of the fenestration. Arterial ischemia will inevitably result when a fenestration that deviates from the branch arterial opening occurs.

Furthermore, for the artificial blood vessel with the open window and the wide holes, the holes are widely distributed in the artificial blood vessel so as to achieve the purpose of not needing to be accurately positioned in use, but the problem of poor sealing effect still exists, and the holes distributed in the lesion part of the artificial blood vessel can cause the sealing failure of the lesion part.

Disclosure of Invention

It is a primary object of the present invention to overcome at least one of the above-mentioned drawbacks of the prior art and to provide an artificial blood vessel with improved sealing effect, avoiding deviation of the fenestration.

In order to achieve the above purpose, the invention adopts the following technical scheme:

according to one aspect of the present invention, there is provided an artificial blood vessel, wherein the artificial blood vessel comprises a body and at least one set of grating sheets; the body is provided with at least one porous part, and the porous part is formed by arranging a plurality of through holes on part of the surface of the body; the grid sheets are arranged on the outer surface of the body, and each group of grid sheets corresponds to each porous part; wherein each group of grid plates comprises at least one grid plate, each grid plate has a base edge, the grid sheet can cover the porous part in an openable and closable manner by being connected to the position, close to the porous part, of the body.

According to one embodiment of the invention, at least one of the grid sheets in each group comprises a plurality of grid sheets, the base edges of the grid sheets are wound around the porous part, so that when the grid sheets in the same group are closed, the porous part is completely covered, and the coverage area of each grid sheet in the same group is smaller than the area of the porous part.

According to one embodiment of the present invention, an included angle between a linear direction in which the base edge of each grid sheet is located and a long axis direction of the body is 45 ° to 90 °.

According to one embodiment of the present invention, the plurality of through holes of each of the porous portions are uniformly distributed; and/or the pore diameters of the plurality of through holes of each porous part are the same; and/or the aperture ratio of each porous part is the same.

According to one embodiment of the invention, the aperture of the through hole is 1.2 mm-3.2 mm; and/or, the porosity of each porous portion is 20% -75%.

According to one embodiment of the present invention, the body is formed with a plurality of porous portions, respectively a first porous portion and at least one second porous portion; the first porous portion is formed circumferentially at the proximal end of the body; the second porous portion is formed at a position other than both end portions of the body.

According to one embodiment of the present invention, at least one of the second porous portions is connected to the first porous portion.

According to one embodiment of the invention, the vascular prosthesis further comprises a plurality of stents; the brackets are arranged on the body, and the brackets are sequentially arranged on the axial direction of the body.

According to one of the embodiments of the present invention, the bracket is of a continuous W-shaped bent structure; and/or the number of the groups of groups, the bracket is made of titanium-nickel alloy.

According to one embodiment of the invention, a plurality of the brackets are uniformly distributed at intervals; and/or the spacing distance between the adjacent brackets is 3 mm-30 mm.

According to the technical scheme, the artificial blood vessel provided by the invention has the advantages and positive effects that:

according to the artificial blood vessel, the opening part is formed on the body, and the grid sheets are arranged on the outer surface of the body to cover the opening part in an openable and closable manner, so that the controllable use of the artificial blood vessel windowing structure is realized. Compared with the existing pre-windowing artificial blood vessel, the invention can open the grating sheet of the opening part corresponding to the position of the lesion part and close the grating sheets of the opening parts at other positions, thereby overcoming the problem of windowing deviation. Meanwhile, compared with the existing wide-hole windowing type artificial blood vessel, the invention does not need to open the grid sheets of all the pore opening parts, thereby ensuring the effectiveness of the closure of the artificial blood vessel.

Drawings

Various objects, features and advantages of the present invention will become more apparent from the following detailed description of the preferred embodiments of the invention, when taken in conjunction with the accompanying drawings. The drawings are merely exemplary illustrations of the invention and are not necessarily drawn to scale. In the drawings, like reference numerals refer to the same or similar parts throughout. Wherein:

FIG. 1 is a schematic illustration of an artificial blood vessel according to an exemplary embodiment;

fig. 2 is another schematic structural view of the artificial blood vessel shown in fig. 1.

Wherein reference numerals are as follows:

100. a body; 101. a proximal end; 1101. a through hole; 111. a first porous portion; 112. a second porous portion; 200. a grid sheet; 210. a base edge; 300. and (3) a bracket.

Detailed Description

Exemplary embodiments that embody features and advantages of the present invention are described in detail in the following description. It will be appreciated that the invention is capable of numerous modifications, all of which are possible in various embodiments, without departing from the scope of the invention, and the description and drawings are illustrative in nature and not intended to limit the invention.

In the following description of various exemplary embodiments of the invention, reference is made to the accompanying drawings, which form a part hereof, and in which are shown by way of illustration various exemplary structures, systems, and steps in which aspects of the invention may be practiced. It is to be understood that other specific arrangements of parts, structures, example devices, systems, and steps may be utilized and structural and functional modifications may be made without departing from the scope of the present invention. Moreover, although the terms "upper end," "lower end," "between," "side," and the like may be used herein to describe various example features and elements of the present invention, these terms are used herein for convenience only, e.g., in terms of the orientation of the examples depicted in the figures. Nothing in this specification should be construed as requiring a particular three-dimensional orientation of the structure in order to fall within the scope of the invention.

Referring to fig. 1, a schematic diagram of an artificial blood vessel capable of embodying the principles of the present invention is representatively illustrated in fig. 1. In this exemplary embodiment, the artificial blood vessel proposed by the present invention is described by taking an artificial blood vessel suitable for a position near an arterial branch or the like as an example. Those skilled in the art will readily appreciate that various modifications, additions, substitutions, deletions, or other changes may be made to the embodiments described below for use of the prosthetic blood vessel in other vascular locations or environments, and such changes are still within the principles of the prosthetic stent 300 vessel presented herein.

As shown in fig. 1, in the present embodiment, the artificial blood vessel according to the present invention mainly includes a body 100, at least one set of grid sheets, and a plurality of stents 300. Accordingly, fig. 1 specifically illustrates a state in which one of the barrier 200 of the artificial blood vessel is opened, and the illustrated opened state of the barrier 200 is intended to facilitate understanding, and is not intended to limit the true opened state of the artificial stent 300 when the blood vessel is in a working environment such as in the vicinity of an arterial branch. Meanwhile, referring to fig. 2 in conjunction, another schematic structure of the artificial blood vessel is representatively illustrated in fig. 2, which specifically illustrates a state in which one of the grating sheets 200 of the artificial blood vessel is closed. The structure, connection manner and functional relationship of each part of the blood vessel of the artificial stent 300 according to the present invention will be described in detail with reference to the above drawings.

As shown in fig. 1 and 2, in the present embodiment, the body 100 of the artificial blood vessel is formed with two porous portions, and the porous portions may be formed by forming a plurality of through holes 1101 on a part of the surface of the body 100. Specifically, only two porous portions are shown in the drawings, and it is easily understood that when the body 100 is formed with a plurality of porous portions, the positions of other porous portions may be located at various places of the body 100, for example, both end portions, a middle portion, or a rear surface of the view shown in the drawings, etc., without being limited to the present embodiment. The range of each porous portion defined on the body 100 may be various shapes such as rectangular, circular, etc., and may be flexibly adjusted according to the vascular structure and the lesion position and shape near the arterial branch, and is not limited to this embodiment.

Further, as shown in fig. 1, in the present embodiment, the plurality of through holes 1101 of each porous portion are preferably arranged in a uniformly distributed manner.

Further, in the present embodiment, the hole diameters of the plurality of through holes 1101 of each porous portion are the same.

Further, in the present embodiment, the aperture ratio of each porous portion is the same.

In this embodiment, the porous portion and the plurality of through holes 1101 are preferably designed so that the uniformity of blood passing through the porous portion can be improved, and the trafficability of the porous portions at different positions can be substantially uniform, without restricting the selection of the porous portions at different positions due to the difference in trafficability.

Further, in the present embodiment, the aperture of the through hole 1101 may be preferably 1.2mm to 3.2mm. The porosity of each porous portion may preferably be 20% to 75%. The design of the aperture of the through hole 1101 and the porosity of the porous portion can be flexibly adjusted according to the application environment of the artificial blood vessel and the requirement on the blood passing property, and is not limited to the present embodiment.

As shown in fig. 1 and 2, in the present embodiment, two porous portions formed on the body 100 are a first porous portion 111 and a second porous portion 112, respectively. Specifically, the first porous portion 111 is formed circumferentially at the proximal end 101 (port position) of the body 100. The second porous portions 112 are formed at positions other than the both end portions of the body 100. As shown in fig. 1 and 2, among others, in the present embodiment, the first porous portion 111 serves as a transition region, between the artificial blood vessel free region and the second porous portion. The second porous portion 112 is located as a functional region having selectivity at an opening portion of the target blood vessel, and can selectively open the target blood vessel. There is no medium caliber branch artery opening at the distal end of the body 100, so no porous region is required.

Further, the second porous portion 112 may be preferably connected to the first porous portion 111, and the grid 200 is not provided on the first porous portion 111. In addition, the number of the second porous portions 112 may be plural, and the positions of the plural second porous portions 112 may be flexibly selected at any position other than the two ends of the body 100, and are not limited to being connected to the first porous portion 111.

As shown in fig. 1 and 2, in the present embodiment, the grid sheets 200 are disposed in groups on the outer surface of the body 100, and each group of grid sheets corresponds to each porous portion formed by the body 100, respectively. Specifically, taking a group of grid sheets corresponding to one of the porous portions formed in the body 100 as an example, when the porous portion has a rectangular shape, the set of grid sheets corresponding thereto may include four grid sheets 200, and each grid sheet 200 has a base edge 210. The base edges 210 of the four grid sheets 200 are respectively connected to the positions of the body 100 near the four edges of the porous portion, and each grid sheet 200 can be turned around the base edge 210 relative to the body 100, so that the group of grid sheets can cover the porous portion of the body 100 in an openable and closable manner.

As shown in fig. 1 and 2, in the present embodiment, the second porous portion 112 is substantially rectangular, and the corresponding set of grid sheets includes four grid sheets 200, and each of the four grid sheets 200 is adjacent to two opposite sides of the second porous portion 112 in the axial direction of the body 100. Wherein, when the four grid sheets 200 are closed, the second porous portion 112 can be completely covered, and the coverage area of each grid sheet 200 in the same group is preferably smaller than the area of the second porous portion 112.

In other embodiments, the gate 200 is not limited to the above-described design of the present embodiment. For example, a group of the grid sheets corresponding to one porous portion may be one sheet, and the area of the grid sheet is preferably slightly larger than that of the porous portion so as to entirely cover the porous portion by the grid sheet 200.

As another example, the arrangement of the base edge 210 of the grid 200 is not limited to being perpendicular to the long axis direction of the body 100, and the grid 200 is not limited to corresponding to a part of the side edges of the porous portion. The grid 200 may also be disposed obliquely to the side of the porous portion at a position adjacent to the body 100 of the porous portion, and the included angle between the linear direction of the base edge 210 of each grid 200 and the long axis direction of the main body 100 is 45 ° -90 ° (in this embodiment).

In the present embodiment, as shown in fig. 1 and 2, a plurality of brackets 300 are provided to the body 100, and are arranged sequentially in the axial direction of the body 100.

Further, as shown in fig. 1 and 2, in the present embodiment, the bracket 300 may preferably have a continuous W-shaped bent structure. In other embodiments, the stent 300 may also be selected from other structures of the existing stent prosthesis, and is not limited to this embodiment.

Further, in the present embodiment, the material of the bracket 300 may be preferably titanium-nickel alloy. In other embodiments, the stent 300 may be made of other materials used in the existing stent prosthesis, and is not limited to this embodiment.

Further, in the present embodiment, the respective holders 300 are preferably uniformly distributed at intervals. Still further, the spacing distance between adjacent stents 300 is preferably 3mm to 30mm. In other embodiments, the spacing between adjacent stents 300 may be selected from the design of existing stent grafts, or non-uniform distribution, and is not limited to this embodiment.

Based on the above detailed description of an embodiment of the artificial blood vessel, the manner of placement of the artificial blood vessel according to the present invention is approximately as follows: in operation, when an artificial blood vessel is placed in the blood vessel lumen, the grid 200 covers the opening portion in an initial state. An operator can directly open the grid sheet 200 at the opening position of the branch artery through the hole, so as to realize the function of selectively opening the window, thereby opening the blood flow of the branch artery, and simultaneously realizing the aims of repairing the lesion and opening the branch artery.

It should be noted herein that the vascular prosthesis shown in the drawings and described in this specification is merely one example of the wide variety of vascular prostheses that can employ the principles of the present invention. It should be clearly understood that the principles of the present invention are in no way limited to any of the details of the vascular prosthesis or any of the components of the vascular prosthesis shown in the drawings or described in the present specification.

In summary, according to the artificial blood vessel provided by the invention, the opening part is formed on the body, and the grid sheet is arranged on the outer surface of the body to cover the opening part in an openable and closable manner, so that the controllable use of the artificial blood vessel windowing structure is realized. Compared with the existing pre-windowing artificial blood vessel, the invention can open the grating sheet of the opening part corresponding to the position of the lesion part and close the grating sheets of the opening parts at other positions, thereby overcoming the problem of windowing deviation. Meanwhile, compared with the existing wide-hole windowing type artificial blood vessel, the invention does not need to open the grid sheets of all the pore opening parts, thereby ensuring the effectiveness of the closure of the artificial blood vessel.

Exemplary embodiments of the present proposed artificial blood vessel are described and/or illustrated in detail above. Embodiments of the invention are not limited to the specific embodiments described herein, but rather, components and/or steps of each embodiment may be utilized independently and separately from other components and/or steps described herein. Each component and/or each step of an embodiment may also be associated with other components and/or steps of other embodiments are used in combination. When introducing elements/components/etc. that are described and/or illustrated herein, the terms "a," "an," and "the" are intended to mean that there are one or more of the elements/components/etc. The terms "comprising," "including," and "having" are intended to be inclusive and mean that there may be additional elements/components/etc., in addition to the listed elements/components/etc. Furthermore, the terms "first" and "second" and the like in the claims and in the description are used for descriptive purposes only and not for numerical limitation of their subject matter.

While the invention has been described in terms of various specific embodiments, those skilled in the art will recognize that the invention can be practiced with modification within the spirit and scope of the claims.

Claims

1. An artificial blood vessel, comprising:

the device comprises a body, a plurality of holes and a plurality of connecting rods, wherein at least one porous part is formed on the body, and the porous part is formed by opening a plurality of through holes on part of the surface of the body; and

at least one group of grid sheets arranged on the outer surface of the body, wherein each group of grid sheets corresponds to each porous part;

each group of grid plates comprises at least one grid plate, and each grid plate is provided with a base edge so as to be connected to the position, close to the porous part, of the body, so that the grid plates can cover the porous part in an openable and closable manner;

wherein, at least one group of each group of grid sheets comprises a plurality of grid sheets, and the substrate edges of the plurality of grid sheets are wound around the periphery of the porous part, so that when the grid sheets of the same group are closed, the porous part is completely covered, and the coverage area of each grid sheet of the same group is smaller than the area of the porous part.

2. The artificial blood vessel according to claim 1, wherein an angle between a straight line direction in which the base edge of each of the grating sheets is located and a long axis direction of the body is 45 ° to 90 °.

3. The vascular prosthesis of claim 1, wherein a plurality of the through holes of each of the porous portions are uniformly distributed; and/or the pore diameters of the plurality of through holes of each porous part are the same; and/or the aperture ratio of each porous part is the same.

4. The artificial blood vessel according to claim 1, wherein the aperture of the through hole is 1.2 mm-3.2 mm; and/or, the porosity of each porous portion is 20% -75%.

5. The artificial blood vessel according to claim 1, wherein the body is formed with a plurality of porous portions, respectively:

a first porous portion formed circumferentially at a proximal end of the body; and

at least one second porous portion formed at a position other than both end portions of the body.

6. The vascular prosthesis of claim 5, wherein at least one of the second porous portions is connected to the first porous portion.

7. The vascular prosthesis of any of claims 1 to 6, further comprising:

the brackets are arranged on the body and are sequentially arranged on the axial direction of the body.

8. The vascular prosthesis of claim 7, wherein the stent is in a continuous "W" shaped bent configuration; and/or the bracket is made of titanium-nickel alloy.

9. The vascular prosthesis of claim 7, wherein a plurality of the stents are spaced evenly apart; and/or the spacing distance between the adjacent brackets is 3 mm-30 mm.