CN108048303B - A kind of pharmaceuticals industry enzyme Preparation equipment - Google Patents
A kind of pharmaceuticals industry enzyme Preparation equipment Download PDFInfo
- Publication number
- CN108048303B CN108048303B CN201810141626.2A CN201810141626A CN108048303B CN 108048303 B CN108048303 B CN 108048303B CN 201810141626 A CN201810141626 A CN 201810141626A CN 108048303 B CN108048303 B CN 108048303B
- Authority
- CN
- China
- Prior art keywords
- sliding
- gear
- sliding groove
- sliding shoe
- motor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 102000004190 Enzymes Human genes 0.000 title claims abstract description 15
- 108090000790 Enzymes Proteins 0.000 title claims abstract description 15
- 239000003814 drug Substances 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 230000001681 protective effect Effects 0.000 claims description 57
- 230000017525 heat dissipation Effects 0.000 claims description 7
- 238000001816 cooling Methods 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 6
- 239000007787 solid Substances 0.000 claims 2
- 238000009434 installation Methods 0.000 claims 1
- 239000007788 liquid Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000006555 catalytic reaction Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229940126534 drug product Drugs 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/14—Bioreactors or fermenters specially adapted for specific uses for producing enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Centrifugal Separators (AREA)
Abstract
The invention discloses a kind of pharmaceuticals industry enzyme Preparation equipments,Including Rack Body and concentrator bowl,Opening is provided in the Rack Body towards left operating cavity,It is provided with rotation slot in the operating cavity bottom wall,The movable chamber being additionally provided in the Rack Body below the rotation slot,The rotation axis extended up and down is rotatably mounted between the rotation slot and the movable chamber by bearing,The rotor plate being fixedly connected with the rotation axis upper end is rotatably mounted in the rotation slot,The rotation axis lower end extend into the movable chamber and is installed with first gear,The first sliding groove that left and right extends is provided in the movable chamber bottom wall,The first sliding shoe that can be horizontally slipped is installed in first sliding groove,Opening is provided in first sliding shoe towards right thread groove,Screw-thread fit is equipped with the first threaded rod in the thread groove,The first threaded rod right end and the first motor be connected by power being fixedly mounted in the first sliding groove right end wall.
Description
Technical field
The present invention relates to pharmaceutical technology field, specifically a kind of pharmaceuticals industry enzyme Preparation equipment.
Background technology
Enzyme is the large biological molecule with living things catalysis ability extracted from biological (including animal, plant, microorganism),
It is aided with other compositions, for accelerating pharmaceutical processing process and improve drug product quality, multiple working procedure can be passed through when extraction, and its
Middle centrifugation purification is essential one of important procedure, and centrifugation purification carries out point of cell by running at high speed for centrifuge
From, once but traditional centrifuge maloperation, can operating personnel be caused with larger injury, therefore, traditional centrifuge is deposited
In prodigious security risk.
Invention content
Deficiency in view of the above technology, the present invention propose a kind of pharmaceuticals industry enzyme Preparation equipment.
A kind of pharmaceuticals industry enzyme Preparation equipment of apparatus of the present invention, including Rack Body and concentrator bowl, in the Rack Body
It is provided with the operating cavity being open towards a left side, rotation slot is provided in the operating cavity bottom wall, is additionally provided with and is located in the Rack Body
Movable chamber below the rotation slot is rotatably mounted between the rotation slot and the movable chamber by bearing upper downward
The rotation axis stretched, is rotatably mounted with the rotor plate being fixedly connected with the rotation axis upper end in the rotation slot, described turn
Moving axis lower end extend into the movable chamber and is installed with first gear, and left and right is provided in the movable chamber bottom wall and is extended
The first sliding groove, the first sliding shoe that can be horizontally slipped is installed in first sliding groove, is set in first sliding shoe
It is equipped with the thread groove being open towards the right side, screw-thread fit is equipped with the first threaded rod, the first threaded rod right end in the thread groove
With the first motor be connected by power being fixedly mounted in the first sliding groove right end wall, first sliding shoe upper surface left side
It is installed with the fixed link upwardly extended, the fixed link upper end is installed with the locking level extended to the right, the locking
Bar right side is provided with the locking teeth coordinated with the first gear, and peace is installed on the right side of first sliding shoe upper surface
Block is filled, is provided with opening up fixing groove in the mounting blocks, is installed with the second motor in the fixing groove, described the
It is installed with the second gear engaged with the first gear on the output shaft of two motors, is set in the first sliding groove bottom wall
It is equipped with the second sliding groove, the sliding protrusion being fixedly connected with first sliding shoe is slidably fitted in second sliding groove,
The second sliding groove right end wall is installed with the power supply block being electrically connected with city, and sliding protrusion right side is fixedly installed
With the conductive sheet of the power supply block cooperation, downward opening sliding cavity, the sliding cavity are provided in the operating cavity upper end wall
The third sliding groove extended downwardly is provided in right end wall, the third sliding groove is communicated with the operating cavity and sliding cavity,
The second sliding shoe that can slide up and down is installed, screw-thread fit is equipped in the second sliding shoe in the third sliding groove
Two threaded rods, the second threaded rod upper and lower ends are installed in rotation on respectively in the third sliding groove roof and bottom wall,
And second threaded rod upper end is connect with the third motor power for being fixedly mounted on the Rack Body upper surface, described second slides
Motion block left side upper end is installed with the upper supporting plate extended to the left, is installed with to downward on the left of the upper supporting plate lower face
The protective plate stretched, the second sliding shoe left side lower end is installed with to be extended and is fixedly connected with the protective plate to the left
Lower carrier plate is rotatably mounted with protective cover by bearing in the lower carrier plate, is provided in the protective cover downward opening
Chamber, the protection chamber roof is protected to be installed with elastic sealing gasket, heat dissipation is provided in the Rack Body, the heat dissipation includes
Be arranged the movable chamber left end wall and with the first radiating groove for communicating of outside and be arranged in the movable chamber right end wall and
With the second radiating groove for communicating of outside, cooling fan, described mounting blocks or so end face are installed in second radiating groove
It is installed with the first heat sink, the second heat dissipation being bonded with second outer surface of motor is additionally provided in the mounting blocks
Plate is also symmetrically set with the radiating block for connecting first heat sink and the second heat sink in the mounting blocks, to institute
Generated heat can be dispersed into the movable chamber when stating the second motor operation, and can be dispersed into institute by the cooling fan
It states outside Rack Body, to can avoid heat build-up.
Valuably or illustratively, wherein the conductive sheet is electrically connected with the third motor, in the conductive sheet
When offseting with the power supply block, the third electrical power can be made, thus can control the third motor operating.
Valuably or illustratively, wherein the protective cover is located at right over the rotor plate, and the protection chamber diameter
More than the outer diameter of the concentrator bowl.
Valuably or illustratively, wherein first sliding shoe right side offsets with the first sliding groove right end wall
When, the conductive sheet offsets with the power supply block, and the second gear is disengaged from the first gear, and the locking teeth
Coordinate with the first gear；It is described to lead when first sliding shoe left side and the first sliding groove left end wall offset
Electric piece offsets with power supply block disengaging, and the locking teeth is detached from the first gear to be coordinated, and the second gear and institute
State first gear engagement.
Valuably or illustratively, wherein the diameter of the second gear is more than the diameter of the first gear.
Valuably or illustratively, wherein the rotor plate upper surface is concordant with the operating cavity bottom wall, to facilitate
Concentrator bowl is stated to be loaded on the rotor plate.
The beneficial effects of the invention are as follows：
In the initial state due to apparatus of the present invention, first sliding shoe right side and the first sliding groove right end wall
It offsets, the conductive sheet offsets with the power supply block, and the second gear is disengaged from the first gear, and the locking
Tooth coordinates with the first gear, and the second sliding shoe upper surface offsets with the third sliding groove roof, the protective plate
It is contracted in the sliding cavity with protective cover, to be prevented when loading on the rotor plate or unloading the concentrator bowl
The rotation of the rotor plate, to which processing safety can be improved；
When in use, cell liquid is injected into the concentrator bowl for apparatus of the present invention, and the concentrator bowl is loaded into institute
It states on rotor plate, then starts the third motor, the third motor drives second threaded rod to rotate forward, and described the
Two threaded rods can drive the second sliding shoe slide downward, the second sliding shoe can drive the protective plate and protective cover to
Lower movement during the protective cover moves down, can be such that the concentrator bowl is nested into the protection chamber, when described second
When sliding shoe lower face offsets with third sliding groove bottom wall, the protective plate separates the operating cavity, the protective cover
Bottom face offsets with the rotor plate, and the elastic sealing gasket offsets with the concentrator bowl upper surface, then starts described
One motor, the first motor can drive first sliding shoe to slide to the left by first threaded rod, and described first slides
Motion block can drive the fixed link, mounting blocks and sliding protrusion to slide to the left, so as to make the conductive sheet and the power supply
Block is detached from cooperation, and the locking teeth and the first gear are detached from and coordinate, when first sliding shoe left side and described the
When one sliding groove left end wall offsets, the second gear is engaged with the first gear, then restarts second motor, institute
Stating the second motor drives the second gear rotation, the second gear to drive the first gear rotation, the first gear
The rotor plate high-speed rotation is driven by the rotation axis, since the protective cover can rotate in the lower carrier plate, and institute
It states protective cover to be tightly bonded the concentrator bowl with the rotor plate, to which the concentrator bowl can follow the rotor plate high speed to turn
It moves and centrifugally operated is carried out to cell liquid；
Since in the concentrator bowl high-speed rotation, the concentrator bowl is isolated from the outside by the protective plate, to significantly
Increase safety；
After the completion of cell separation, stop second motor, and first motor described in reverse starting, the first motor can
First sliding shoe is driven to slide to the right by first threaded rod, during first sliding shoe slides to the right,
The second gear can be disengaged from the first gear, and when first sliding shoe right side and first sliding groove
When right end wall offsets, the conductive sheet offsets with the power supply block, and the locking teeth coordinates with the first gear, so as to make
The rotor plate stops operating, and then third motor described in reverse starting, the third motor can pass through second screw thread again
Bar drives the third sliding shoe upward sliding, the third sliding shoe that can drive the protective plate and protective cover upward sliding,
Thus the protective plate and the operating cavity is opened wide, the protective cover can expose the concentrator bowl, at this time can be by concentrator bowl
It is removed from the rotor plate, so as to carry out next step operation；
Apparatus of the present invention are simple in structure, easy to use, stable, safe to use.
Description of the drawings
It, below will be to embodiment or existing in order to illustrate more clearly of inventive embodiments or technical solution in the prior art
Attached drawing is briefly described needed in technology description, it should be apparent that, the accompanying drawings in the following description is only to invent
Some embodiments for those of ordinary skill in the art without creative efforts, can also basis
These attached drawings obtain other attached drawings.
Fig. 1 is a kind of structural schematic diagram of pharmaceuticals industry enzyme Preparation equipment of the present invention.
Fig. 2 is structural schematic diagram when protective plate separates operating cavity in Fig. 1.
Fig. 3 is the structural schematic diagram of arrow direction in Fig. 1.
Specific implementation mode
All features disclosed in this specification or disclosed all methods or in the process the step of, in addition to mutually exclusive
Feature and/or step other than, can combine in any way.
This specification（Including any accessory claim, abstract and attached drawing）Disclosed in any feature, except non-specifically chatting
It states, can be replaced by other alternative features that are equivalent or have similar purpose.That is, unless specifically stated, each feature is only
It is an example in a series of equivalent or similar characteristics.
As shown in Figure 1 to Figure 3, a kind of pharmaceuticals industry enzyme Preparation equipment of apparatus of the present invention, including Rack Body 10 and from
Heart cylinder 12 is provided with opening in the Rack Body 10 towards left operating cavity 11, rotation slot is provided in 11 bottom wall of the operating cavity
14, the movable chamber 17 positioned at 14 lower section of the rotation slot, the rotation slot 14 and the work are additionally provided in the Rack Body 10
It is rotatably mounted with the rotation axis 15 extended up and down by bearing between dynamic chamber 17, is rotatably mounted in the rotation slot 14
There are the rotor plate 13 being fixedly connected with 15 upper end of the rotation axis, 15 lower end of the rotation axis to extend into the movable chamber 17 simultaneously
Be installed with first gear 39, be provided in 17 bottom wall of the movable chamber left and right extend the first sliding groove 20, described first
The first sliding shoe 22 that can be horizontally slipped is installed in sliding groove 20, opening is provided in first sliding shoe 22 towards right spiral shell
Groove, screw-thread fit is equipped with the first threaded rod 23 in the thread groove, 23 right end of the first threaded rod be fixedly mounted on
24 be connected by power of first motor in first sliding groove, 20 right end wall, the fixed peace in 22 upper surface of the first sliding shoe left side
Equipped with the fixed link 18 upwardly extended, 18 upper end of the fixed link is installed with the locking level 16 extended to the right, the locking
16 right side of bar is provided with the locking teeth coordinated with the first gear 39, and peace is fixed on the right side of 22 upper surface of the first sliding shoe
Equipped with mounting blocks 25, it is provided with opening up fixing groove in the mounting blocks 25, second is installed in the fixing groove
Motor 26 is installed with the second gear 28 engaged with the first gear 39 on the output shaft 27 of second motor 26,
It is provided with the second sliding groove 19 in first sliding groove, 20 bottom wall, is slidably fitted in second sliding groove 19 and described
Sliding that one sliding shoe 22 is fixedly connected protrusion 191, second sliding groove, 19 right end wall is installed with to be electrically connected with city
Power supply block 20,191 right sides of the sliding protrusion are fixedly installed the conductive sheet 192 coordinated with the power supply block 20, the behaviour
Make to be provided with downward opening sliding cavity 38 in 11 upper end wall of chamber, extended downwardly is provided in 38 right end wall of the sliding cavity
Three sliding grooves 29, the third sliding groove 29 are communicated with the operating cavity 11 and sliding cavity 38, in the third sliding groove 29
The second sliding shoe 32 that can slide up and down is installed, screw-thread fit is equipped with the second threaded rod 30 in the second sliding shoe 32,
Second threaded rod, 30 upper and lower ends are installed in rotation on respectively in 29 roof of third sliding groove and bottom wall, and described
Second threaded rod, 30 upper end and 31 be connected by power of third motor for being fixedly mounted on 10 upper surface of the Rack Body, described second slides
32 left side upper end of motion block is installed with the upper supporting plate 36 extended to the left, is installed on the left of 36 lower face of the upper supporting plate
The protective plate 37 extended downwardly, 32 left side lower end of the second sliding shoe be installed with to the left extend and with the protective plate
37 lower carrier plates 33 being fixedly connected are rotatably mounted with protective cover 35, the protective cover in the lower carrier plate 33 by bearing
Downward opening protection chamber 350 is provided in 35,350 roof of protection chamber is installed with elastic sealing gasket 34, the machine
Heat dissipation is provided in frame body 10, the heat dissipation includes being arranged in 17 left end wall of the movable chamber and radiating with external first communicated
Slot 45 and the second radiating groove 40 for being arranged in 17 right end wall of the movable chamber and being communicated with outside, second radiating groove 40
In be installed with cooling fan 41,25 or so end face of the mounting blocks is installed with the first heat sink 43, the mounting blocks
It is additionally provided with the second heat sink 42 being bonded with 26 outer surface of the second motor in 25, it is also symmetrical in the mounting blocks 25
It is provided with the radiating block 44 for connecting 43 and second heat sink 42 of the first heat sink, to second motor 26 operation when institute
The heat of generation can be dispersed into the movable chamber 17, and can be dispersed into outside the Rack Body 10 by the cooling fan 41
Portion, to can avoid heat build-up.
Valuably or illustratively, wherein the conductive sheet 192 is electrically connected with the third motor 31, to described
When conductive sheet 192 offsets with the power supply block 20, the third motor 31 can be made to be powered, thus can control the third motor 31
Operating.
Valuably or illustratively, wherein the protective cover 35 is located at right over the rotor plate 13, and the protection chamber
350 diameters are more than the outer diameter of the concentrator bowl 12.
Valuably or illustratively, wherein 22 right side of the first sliding shoe and first sliding groove, 20 right end wall
When offseting, the conductive sheet 192 offsets with the power supply block 20, and the second gear 28 is nibbled with the disengaging of the first gear 39
It closes, and the locking teeth coordinates with the first gear 39；When 22 left side of the first sliding shoe and first sliding groove
When 20 left end walls offset, the conductive sheet 192 offsets with the power supply block 20 disengaging, the locking teeth and the first gear 39
It is detached from cooperation, and the second gear 28 is engaged with the first gear 39.
Valuably or illustratively, wherein the diameter of the second gear 28 is more than the diameter of the first gear 39.
Valuably or illustratively, wherein 13 upper surface of the rotor plate is concordant with 11 bottom wall of the operating cavity, to side
Toilet is stated concentrator bowl 12 and is loaded on the rotor plate 1.
Apparatus of the present invention in the initial state, 22 right side of the first sliding shoe and first sliding groove, 20 right end wall
It offseting, the conductive sheet 192 offsets with the power supply block 20, and the second gear 28 is disengaged from the first gear 39,
And the locking teeth coordinates with the first gear 39,32 upper surface of the second sliding shoe and 29 roof of third sliding groove
It offsets, the protective plate 37 and protective cover 35 are contracted in the sliding cavity 38.
In use, cell liquid is injected into the concentrator bowl 12, and the concentrator bowl 12 is loaded into the rotor plate
On 13, then starting the third motor 31, the third motor 31 drives second threaded rod 30 to rotate forward, and described
Two threaded rods 30 can drive 32 slide downward of the second sliding shoe, the second sliding shoe 32 that can drive 37 He of the protective plate
Protective cover 35 moves down, and during the protective cover 35 moves down, the concentrator bowl 12 can be made to be nested into the protection
In chamber 350, when 32 lower face of the second sliding shoe and 29 bottom wall of third sliding groove offset, the protective plate 37 is by institute
State the partition of operating cavity 11,35 bottom face of the protective cover offsets with the rotor plate 13, and the elastic sealing gasket 34 with it is described
12 upper surface of concentrator bowl offsets, and then starts the first motor 24, and the first motor 24 can pass through first threaded rod
23 driving first sliding shoes 22 slide to the left, first sliding shoe 22 can drive the fixed link 18, mounting blocks 25 with
And sliding protrusion 191 slides to the left, coordinates so as to make the conductive sheet 192 be detached from the power supply block 20, and the locking
Tooth is detached from the first gear 39 to be coordinated, when 22 left side of the first sliding shoe and first sliding groove, 20 left end wall phase
To when, the second gear 28 is engaged with the first gear 39, then restarts second motor 26, second motor
The 26 driving second gears 28 rotate, and the second gear 28 drives the first gear 39 to rotate, the first gear 39
13 high-speed rotation of the rotor plate is driven by the rotation axis 15, since the protective cover 35 can be in the lower carrier plate 33
Rotation, and the concentrator bowl 12 is tightly bonded by the protective cover 35 with the rotor plate 13, so that the concentrator bowl 12 can be with
Centrifugally operated is carried out to cell liquid with 13 high-speed rotation of the rotor plate；
After the completion of cell separation, stop second motor 26, and first motor 24 described in reverse starting, first electricity
Machine 26 can drive first sliding shoe 22 to slide to the right by first threaded rod 23, and first sliding shoe 22 is slided to the right
In dynamic process, the second gear 28 can be disengaged from the first gear 39, and work as 22 right end of the first sliding shoe
When face and first sliding groove, 20 right end wall offset, the conductive sheet 192 offsets with the power supply block 20, the locking teeth and
The first gear 39 coordinates, so as to make the rotor plate 13 stop operating, then third motor 31 described in reverse starting again,
The third motor 31 can drive 32 upward sliding of third sliding shoe, the third sliding by second threaded rod 30
Block 31 can drive 35 upward sliding of the protective plate 37 and protective cover, thus the protective plate 37 and open the operating cavity 11
It opens, the protective cover 35 can expose the concentrator bowl 12, at this time can remove concentrator bowl 12 from the rotor plate 13, to
It can carry out next step operation.
The beneficial effects of the invention are as follows：In the initial state due to apparatus of the present invention, first sliding shoe right side with
The first sliding groove right end wall offsets, and the conductive sheet offsets with the power supply block, the second gear and first tooth
Wheel is disengaged from, and the locking teeth coordinates with the first gear, and the second sliding shoe upper surface is slided with the third
Groove top wall offsets, and the protective plate and protective cover are contracted in the sliding cavity, on the rotor plate load or
The rotation that the rotor plate can be prevented when unloading the concentrator bowl, to which processing safety can be improved；
When in use, cell liquid is injected into the concentrator bowl for apparatus of the present invention, and the concentrator bowl is loaded into institute
It states on rotor plate, then starts the third motor, the third motor drives second threaded rod to rotate forward, and described the
Two threaded rods can drive the second sliding shoe slide downward, the second sliding shoe can drive the protective plate and protective cover to
Lower movement during the protective cover moves down, can be such that the concentrator bowl is nested into the protection chamber, when described second
When sliding shoe lower face offsets with third sliding groove bottom wall, the protective plate separates the operating cavity, the protective cover
Bottom face offsets with the rotor plate, and the elastic sealing gasket offsets with the concentrator bowl upper surface, then starts described
One motor, the first motor can drive first sliding shoe to slide to the left by first threaded rod, and described first slides
Motion block can drive the fixed link, mounting blocks and sliding protrusion to slide to the left, so as to make the conductive sheet and the power supply
Block is detached from cooperation, and the locking teeth and the first gear are detached from and coordinate, when first sliding shoe left side and described the
When one sliding groove left end wall offsets, the second gear is engaged with the first gear, then restarts second motor, institute
Stating the second motor drives the second gear rotation, the second gear to drive the first gear rotation, the first gear
The rotor plate high-speed rotation is driven by the rotation axis, since the protective cover can rotate in the lower carrier plate, and institute
It states protective cover to be tightly bonded the concentrator bowl with the rotor plate, to which the concentrator bowl can follow the rotor plate high speed to turn
It moves and centrifugally operated is carried out to cell liquid；
Since in the concentrator bowl high-speed rotation, the concentrator bowl is isolated from the outside by the protective plate, to significantly
Increase safety；
After the completion of cell separation, stop second motor, and first motor described in reverse starting, the first motor can
First sliding shoe is driven to slide to the right by first threaded rod, during first sliding shoe slides to the right,
The second gear can be disengaged from the first gear, and when first sliding shoe right side and first sliding groove
When right end wall offsets, the conductive sheet offsets with the power supply block, and the locking teeth coordinates with the first gear, so as to make
The rotor plate stops operating, and then third motor described in reverse starting, the third motor can pass through second screw thread again
Bar drives the third sliding shoe upward sliding, the third sliding shoe that can drive the protective plate and protective cover upward sliding,
Thus the protective plate and the operating cavity is opened wide, the protective cover can expose the concentrator bowl, at this time can be by concentrator bowl
It is removed from the rotor plate, so as to carry out next step operation；
Apparatus of the present invention are simple in structure, easy to use, stable, safe to use.
The basic principles, main features and advantages of the present invention have been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and what is described in the above embodiment and the description is only the present invention
Principle, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these variation and
Improvement is both fallen in claimed invention.The claimed scope of the invention is by appended claims and its equivalent circle
It is fixed.
Claims (6)
1. a kind of pharmaceuticals industry enzyme Preparation equipment, including Rack Body and concentrator bowl, it is characterised in that：It is arranged in the Rack Body
There is operating cavity of the opening towards a left side, is provided with rotation slot in the operating cavity bottom wall, is additionally provided in the Rack Body positioned at described
Movable chamber below rotation slot is rotatably mounted between the rotation slot and the movable chamber by bearing and to be extended up and down
Rotation axis is rotatably mounted with the rotor plate being fixedly connected with the rotation axis upper end, the rotation axis in the rotation slot
Lower end extend into the movable chamber and is installed with first gear, and left and right extends the is provided in the movable chamber bottom wall
One sliding groove is equipped with the first sliding shoe that can be horizontally slipped in first sliding groove, is provided in first sliding shoe
Be open towards right thread groove, screw-thread fit is equipped with the first threaded rod in the thread groove, the first threaded rod right end with it is solid
Dingan County is mounted in the first motor be connected by power in the first sliding groove right end wall, is fixed on the left of first sliding shoe upper surface
The fixed link upwardly extended is installed, the fixed link upper end is installed with the locking level extended to the right, and the locking level is right
End face is provided with the locking teeth coordinated with the first gear, and installation is installed on the right side of first sliding shoe upper surface
Block is provided with opening up fixing groove in the mounting blocks, is installed with the second motor in the fixing groove, and described second
It is installed with the second gear engaged with the first gear on the output shaft of motor, is arranged in the first sliding groove bottom wall
There is the second sliding groove, the sliding protrusion being fixedly connected with first sliding shoe, institute are slidably fitted in second sliding groove
State the second sliding groove right end wall and be installed with the power supply block being electrically connected with city, sliding protrusion right side be fixedly installed with
The conductive sheet of the power supply block cooperation, downward opening sliding cavity is provided in the operating cavity upper end wall, and the sliding cavity is right
The third sliding groove extended downwardly is provided in end wall, the third sliding groove is communicated with the operating cavity and sliding cavity, institute
It states and the second sliding shoe that can slide up and down is installed in third sliding groove, screw-thread fit is equipped with second in the second sliding shoe
Threaded rod, the second threaded rod upper and lower ends are installed in rotation on respectively in the third sliding groove roof and bottom wall, and
Second threaded rod upper end is connect with the third motor power for being fixedly mounted on the Rack Body upper surface, second sliding
Block left side upper end is installed with the upper supporting plate extended to the left, is installed with and extends downwardly on the left of the upper supporting plate lower face
Protective plate, the second sliding shoe left side lower end be installed with to the left extend and be fixedly connected down with the protective plate
Support plate is rotatably mounted with protective cover in the lower carrier plate by bearing, is provided in the protective cover downward opening anti-
Chamber is protected, the protection chamber roof is installed with elastic sealing gasket, and heat dissipation is provided in the Rack Body, and the heat dissipation includes setting
Set the movable chamber left end wall and with the first radiating groove for communicating of outside and be arranged in the movable chamber right end wall and with
The second radiating groove that outside communicates, cooling fan is installed in second radiating groove, and described mounting blocks or so end face is solid
Dingan County is equipped with the first heat sink, and the second heat sink being bonded with second outer surface of motor is additionally provided in the mounting blocks,
The radiating block for connecting first heat sink and the second heat sink is also symmetrically set in the mounting blocks, to described the
Generated heat can be dispersed into the movable chamber when two motor operations, and can be dispersed into the machine by the cooling fan
Outside frame body, to can avoid heat build-up.
2. a kind of pharmaceuticals industry enzyme Preparation equipment according to claim 1, it is characterised in that：The conductive sheet with it is described
Third motor is electrically connected, to when the conductive sheet and the power supply block offset, make the third electrical power, thus may be used
Control the third motor operating.
3. a kind of pharmaceuticals industry enzyme Preparation equipment according to claim 1, it is characterised in that：The protective cover is located at institute
It states right over rotor plate, and the protection chamber diameter is more than the outer diameter of the concentrator bowl.
4. a kind of pharmaceuticals industry enzyme Preparation equipment according to claim 1, it is characterised in that：First sliding shoe is right
When end face offsets with the first sliding groove right end wall, the conductive sheet offsets with the power supply block, the second gear and institute
First gear is stated to be disengaged from, and the locking teeth coordinates with the first gear；When first sliding shoe left side and institute
When stating the first sliding groove left end wall and offseting, the conductive sheet offsets with power supply block disengaging, the locking teeth and described first
Gear is detached from cooperation, and the second gear is engaged with the first gear.
5. a kind of pharmaceuticals industry enzyme Preparation equipment according to claim 1, it is characterised in that：The second gear it is straight
Diameter is more than the diameter of the first gear.
6. a kind of pharmaceuticals industry enzyme Preparation equipment according to claim 1, it is characterised in that：The rotor plate upper surface
It is concordant with the operating cavity bottom wall, to facilitate the concentrator bowl to be loaded on the rotor plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810141626.2A CN108048303B (en) | 2018-02-11 | 2018-02-11 | A kind of pharmaceuticals industry enzyme Preparation equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810141626.2A CN108048303B (en) | 2018-02-11 | 2018-02-11 | A kind of pharmaceuticals industry enzyme Preparation equipment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108048303A CN108048303A (en) | 2018-05-18 |
| CN108048303B true CN108048303B (en) | 2018-11-13 |
Family
ID=62126007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810141626.2A Active CN108048303B (en) | 2018-02-11 | 2018-02-11 | A kind of pharmaceuticals industry enzyme Preparation equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108048303B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112322489A (en) * | 2020-11-18 | 2021-02-05 | 周双龙 | Novel textile industry enzyme preparation device |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102564962A (en) * | 2011-12-07 | 2012-07-11 | 北京农业智能装备技术研究中心 | System and method for detecting nutritional components in fruit trees |
| CN202667003U (en) * | 2012-07-06 | 2013-01-16 | 广东顺大食品调料有限公司 | High-speed centrifugal machine |
| CN103789196A (en) * | 2014-01-24 | 2014-05-14 | 海盐县通元弗斯特工艺品厂 | Nut protein extraction device with blowing strip and blowing stirring device |
| CN206276515U (en) * | 2016-12-14 | 2017-06-27 | 沧州渤洋管道集团有限公司 | A kind of centrifuge apparatus |
| CN107314922A (en) * | 2017-06-23 | 2017-11-03 | 中国计量大学 | Extraction element is crushed in food stirring |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10433675B2 (en) * | 2016-02-02 | 2019-10-08 | Conair Corporation | Adjustable slicing mechanism for a food processor |
-
2018
- 2018-02-11 CN CN201810141626.2A patent/CN108048303B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102564962A (en) * | 2011-12-07 | 2012-07-11 | 北京农业智能装备技术研究中心 | System and method for detecting nutritional components in fruit trees |
| CN202667003U (en) * | 2012-07-06 | 2013-01-16 | 广东顺大食品调料有限公司 | High-speed centrifugal machine |
| CN103789196A (en) * | 2014-01-24 | 2014-05-14 | 海盐县通元弗斯特工艺品厂 | Nut protein extraction device with blowing strip and blowing stirring device |
| CN206276515U (en) * | 2016-12-14 | 2017-06-27 | 沧州渤洋管道集团有限公司 | A kind of centrifuge apparatus |
| CN107314922A (en) * | 2017-06-23 | 2017-11-03 | 中国计量大学 | Extraction element is crushed in food stirring |
Non-Patent Citations (1)
| Title |
|---|
| "蛋白质组学中的固定化酶反应器制备的研究进展";张凌怡等;《色谱》;20151108;第33卷(第11期);第1121-1125页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108048303A (en) | 2018-05-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108057374A (en) | Mixing plant dispersion impeller chamber structure for use | |
| CN108048303B (en) | A kind of pharmaceuticals industry enzyme Preparation equipment | |
| CN208130858U (en) | A kind of hybrid reaction tank convenient for cleaning | |
| CN108452959A (en) | A kind of pharmaceuticals industry enzyme preparation facilities | |
| CN209775251U (en) | Polypropylene waste plastic hot melting machine | |
| CN208380249U (en) | A kind of novel electric power construction lifting equipment | |
| CN212658006U (en) | Rake type dryer rake body for preparing olmesartan medoxomil | |
| CN205870924U (en) | Centrifugal thermoplastic mixer | |
| CN108977339A (en) | A kind of pharmaceuticals industry enzyme preparation structure | |
| CN105965522B (en) | A kind of high-altitude changes the bulb robot automatically | |
| CN210425974U (en) | Continuous desiccator of ginkgo leaf | |
| CN213171642U (en) | Biodegradable sewage treatment ware | |
| CN213569309U (en) | Screw rod lifter with stabilizing structure | |
| CN208615992U (en) | A kind of haul cart for Production of bearing | |
| CN212477057U (en) | Finished product storage device for hosiery machine | |
| CN210773230U (en) | Pharmaceutical drying and dehydrating device for pharmacy | |
| CN208190605U (en) | A kind of photovoltaic generating monitoring device | |
| CN109121576A (en) | Digging apparatus is used in a kind of plantation of tree peony | |
| CN207431108U (en) | A kind of dise knife plate shearing machine side silk guider convenient for collection waste material function | |
| CN108544549A (en) | A kind of novel anti-slip sole preparation facilities | |
| CN207847626U (en) | A kind of electric cable for coal mining machine turnover device | |
| CN108330056B (en) | A kind of food enzyme preparation facilities | |
| CN219567995U (en) | Quenching device for roller production | |
| CN211812457U (en) | Discharge apparatus is used in bio-organic fertilizer production | |
| CN213792238U (en) | Medical ultra-speed refrigerated centrifuge |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240903 Address after: No. 10 Longhai Road, Economic and Technological Development Zone, Qinhuangdao City, Hebei Province 066011 Patentee after: Qinhuangdao Zizhu Pharmaceutical Co.,Ltd. Country or region after: China Address before: 322000 No. 81, upper leaf village, fo Tang Town, Yiwu, Jinhua, Zhejiang Patentee before: YIWU LVMEI BIOTECHNOLOGY Co.,Ltd. Country or region before: China |