CN107569778B - Neutron therapeutic device - Google Patents
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- CN107569778B CN107569778B CN201610517977.XA CN201610517977A CN107569778B CN 107569778 B CN107569778 B CN 107569778B CN 201610517977 A CN201610517977 A CN 201610517977A CN 107569778 B CN107569778 B CN 107569778B
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- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 18
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- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
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Abstract
The invention discloses a neutron treatment device, which comprises a beam shaping body, a neutron generating part arranged in the beam shaping body, a tube bundle for transmitting an ion beam to the neutron generating part, a deflection electromagnet for changing the transmission direction of the ion beam and a collimator, wherein the beam shaping body comprises a retarder and a reflector which is wrapped on the periphery of the retarder, the neutron generating part generates neutrons after being irradiated by the ion beam, the retarder decelerates neutrons generated by the neutron generating part to an epithermal neutron energy region, the reflector guides the deviated neutrons back to improve the neutron intensity in the epithermal neutron energy region, the tube bundle is provided with an axis, and the beam shaping body can rotate around the axis of the tube bundle to irradiate an irradiated body at different angles. The whole neutron treatment device can irradiate at different angles only by rotating the structure of the whole neutron treatment device through the arrangement of the supporting frame, the beam shaping body and the deflection magnet, and the device has the advantages of simple structure, light operation and easy realization.
Description
Technical Field
The invention relates to a radioactive ray irradiation device, in particular to a neutron treatment device.
Background
In general, a neutron treatment device used in a boron neutron capture treatment device requires irradiation of an irradiation subject at a plurality of angles, and conventionally, in order to achieve such multi-angle irradiation, the neutron treatment device is usually fixed to a rotating device having a large structure, and the neutron treatment device is rotated by rotation of the rotating device. Obviously, the neutron treatment device has very huge structure, the rotation of the neutron treatment device is driven by an external rotating device, the neutron treatment device can be realized by the rotating device which is necessarily huge than the neutron treatment device, and the rotation of the neutron treatment device and the rotating device is simultaneously satisfied, so that a very large space is required, the whole device is heavy, has low applicability and is unfavorable for the miniaturization design of the neutron treatment device.
Disclosure of Invention
In order to provide a neutron therapeutic apparatus capable of performing multi-angle neutron irradiation, one aspect of the present invention provides a neutron therapeutic apparatus comprising a beam shaping body, a neutron generating section provided in the beam shaping body, a tube bundle for transmitting an ion beam to the neutron generating section, a deflection electromagnet for changing a transmission direction of the ion beam, and a collimator, wherein the beam shaping body comprises a retarder for decelerating neutrons generated from the neutron generating section to an epithermal neutron energy region after the neutron generating section is irradiated with the ion beam, and a reflector provided around the retarder for guiding off-set neutrons back to increase neutron intensity in the epithermal neutron energy region, the collimator concentrates the neutrons generated from the neutron generating section, the neutron therapeutic apparatus has an irradiation space for irradiating the irradiated body, and the beam shaping body is connected with a shielding body for shielding radiation leaking from the beam shaping body, and the shielding body is capable of shielding the irradiation space with the movement of the beam shaping body.
Further, the neutron therapeutic device further comprises a support frame, the beam shaping body is fixed on the support frame, the surface of the support frame is concavely provided with a containing space communicated with the irradiation space, a gap is formed among the beam shaping body, the containing space and the irradiation space, and the shielding body covers the gap.
Further, the shielding body comprises at least two shielding pieces, the shielding pieces are positioned on two sides of the beam shaping body, one end of each shielding piece is connected with the other end of the supporting frame and is fixedly held on the beam shaping body, when the beam shaping body moves, the shielding piece positioned on one side of the beam shaping body stretches, and the shielding piece positioned on the other side of the beam shaping body contracts.
Further, the shielding piece is composed of a plurality of shielding parts which are buckled end to end, and when the shielding piece stretches, the shielding parts stretch one by one to be buckled with each other; when the shield is contracted, the shield portions are stacked one by one.
Further, the end parts of the shielding parts, which are mutually buckled, are provided with clamping parts, and the clamping parts can move on the surface of the shielding parts and are mutually buckled and positioned with the adjacent clamping parts.
Further, the shielding parts are arranged in an arc shape, and the shielding parts are in an arc shape after the shielding parts are stretched one by one.
Further, the height of the accommodating space is not smaller than the thickness of the shielding body, and the width of the shielding body is not smaller than the width of the accommodating space.
Further, the shielding body is connected to two sides of the beam shaping body and is integrally arranged, and when the beam shaping body moves, the shielding body can rotate together with the beam shaping body around the supporting frame and always covers the beam shaping body, the accommodating space and the irradiation space to form a gap.
Further, the width of the shielding body is not smaller than the width of the accommodating space.
Further, the support frame comprises a first support portion, the first support portion is provided with a first track, the beam shaping body is fixedly held on the first track, the first track is concavely arranged on the surface of the first support portion to form the accommodating space communicated with the irradiation space, the first support portion is arranged in an arc shape, and the first track is arranged in an arc shape with the same center of circle as the first support portion.
Compared with the prior art, the application has the following beneficial effects: according to the neutron therapeutic device, the shielding body is arranged in the gap formed among the beam shaping body, the accommodating space and the irradiation space, so that the radiation leaking out of the beam shaping body in the irradiation treatment process of the neutron therapeutic device is shielded, and the overall attractiveness of the neutron therapeutic device is facilitated.
In another aspect of the present invention, there is also disclosed a neutron treatment device capable of rotating irradiation, the neutron treatment device including a beam shaping body, a neutron generating section provided in the beam shaping body, a tube bundle that transmits an ion beam to the neutron generating section, a deflection electromagnet that changes a transmission direction of the ion beam, and a collimator, the beam shaping body including a retarder that generates neutrons after irradiation with the ion beam and a reflector that is wrapped around the retarder, the retarder decelerating neutrons generated from the neutron generating section to a preset energy spectrum, the reflector guiding the deviated neutrons back to increase neutron intensity within the preset energy spectrum, the collimator intensively irradiating neutrons generated from the neutron generating section, the neutron treatment device having an irradiation space that irradiates an irradiated object, the tube bundle having an axis, the beam shaping body being rotatable around the axis of the tube bundle so as to irradiate the irradiated object in the irradiation space at different angles.
Further, the neutron treatment device also comprises a support frame, the beam shaping body is fixed on the support frame, and the beam shaping body rotates around the axis of the tube bundle and moves on the support frame.
Further, the tube bundle includes a first tube bundle and a third tube bundle connected to the first tube bundle, the axis includes a first axis of the first tube bundle and a second axis of the third tube bundle, and the beam shaper is rotatable about the first axis of the first tube bundle or the second axis of the third tube bundle.
Further, a first included angle is formed between the first tube bundle and the third tube bundle, and the size of the first included angle can be changed to adjust the position relation between the beam shaping body and the irradiated body in the irradiation space.
Further, the support frame comprises a first support part, the irradiation space is located below the first support part, the first support part is provided with a first track, the beam shaping body is fixedly held on the first track of the support frame, the first track is concavely arranged on the support frame to form a containing space communicated with the irradiation space, and the collimator extends into the irradiation space from the containing space.
Further, the first supporting portion is arranged in an arc shape, the first track is arranged in an arc shape with the same circle center as the first supporting portion, and the first track is concavely arranged from the arc surface of the first supporting portion.
Further, the tube bundle further comprises a second tube bundle, the second tube bundle is connected to the neutron generating part, a second included angle is formed between the second tube bundle and the third tube bundle, and the size of the second included angle can be changed to adjust the position relation between the beam integral body and the irradiated body in the irradiation space.
Further, the deflection magnet is fixedly held on the support frame, the deflection magnet comprises a first deflection magnet positioned between the first tube bank and the third tube bank and a second deflection magnet positioned between the second tube bank and the third tube bank, the transmission direction of the ion beam in the first tube bank is changed through the first deflection magnet and then is transmitted to the third tube bank, the transmission direction of the ion beam in the third tube bank is changed through the second deflection magnet and then is transmitted to the second tube bank, and the ion beam in the second tube bank irradiates to the neutron generation part to generate a neutron beam for irradiation by the neutron ray device.
Further, the support frame is further provided with a second support portion for supporting the second deflection magnet, the second support portion being provided with a second track in which the second support portion moves when the beam shaping body moves in the first track.
Further, the support frame is further provided with a third support portion, the first deflection magnet is fixedly held on the third support portion, the first tube bundle is fixed between the accelerator and the first deflection magnet, the second tube bundle is connected between the beam shaping body and the second deflection magnet, and the third tube bundle is connected between the first deflection magnet and the second deflection magnet.
Compared with the prior art, the application has the following beneficial effects: the setting through support frame, beam integer and deflection magnet makes whole neutron treatment device only need rotatory self structure just can realize that whole neutron treatment device carries out the illumination of different angles, simple structure, and the operation is light, easily realizes.
Drawings
FIG. 1 is a schematic view of the present invention without a support frame;
FIG. 2 is a cross-sectional view of a neutron producing device of the present invention;
FIG. 3 is a schematic view of the present invention after the support frame is installed;
FIG. 4 is a schematic view of a beam shaping body held in a first track according to an embodiment of the present invention;
FIG. 5 is a top view of the beam shaping body held in the support first track;
FIG. 6 is a schematic view of another angle of the present invention;
fig. 7 is a schematic diagram of the present invention when the first included angle a1 is changed;
FIG. 8 is a schematic diagram of the present invention when the second angle a2 is changed
FIG. 9 is a schematic view of another embodiment of a support stand according to the present invention;
FIG. 10 is a cross-sectional view of a shield in one embodiment of the invention;
FIG. 11 is a state diagram of the shielding portion of the beam shaper of the present invention as it moves to a position in a first trajectory;
FIG. 12 is a state diagram of the shielding portion of the beam shaper of the present invention as it moves in a first trajectory to another position;
FIG. 13 is a top view of the shield of FIG. 8 shown extended;
fig. 14 is a cross-sectional view of a shield in another embodiment of the present invention;
fig. 15 is a state diagram of the shield of fig. 14 when the beam shaping body is moved to a certain position;
fig. 16 is a top view of the shield shown in fig. 10.
Detailed Description
The present invention is described in further detail below with reference to the drawings to enable those skilled in the art to practice the invention by referring to the description.
Neutron irradiation has been increasingly used in recent years as an effective means of treating cancer, where it is most common to provide boron neutron capture therapy where neutrons may be supplied by a nuclear reactor or accelerator. Taking accelerator boron neutron capture therapy as an example, the basic components of accelerator boron neutron capture therapy generally comprise an accelerator for accelerating charged particles (such as protons, deuterons and the like), a neutron generating part and a heat removing system and a beam shaping body, wherein the accelerated charged particles react with a metal neutron generating part to generate neutrons, and proper nuclear reactions are selected according to the required neutron yield and energy, available energy and current of the accelerated charged particles, physicochemical properties of the metal neutron generating part and the like, and the nuclear reactions in common discussion are that 7 Li(p,n) 7 Be and Be 9 Be(p,n) 9 And B, performing an endothermic reaction. The energy threshold values of the two nuclear reactions are respectively 1.881MeV and 2.055MeV, because the ideal neutron source for the boron neutron capture treatment is the epithermal neutrons with the keV energy level, if the protons with the energy only slightly higher than the threshold value are used for bombarding the metal lithium neutron generating part in theory, relatively low-energy neutrons can Be generated, the clinical treatment can Be carried out without too much retarding treatment, however, the proton action cross sections of the two neutron generating parts of lithium metal (Li) and beryllium metal (Be) and the threshold energy are not high, and in order to generate enough neutron flux, the protons with higher energy are generally selected to trigger the nuclear reactions.
Boron neutron captureThe obtained treatment (Boron Neutron Capture Therapy, BNCT) uses the characteristic of boron-containing (10B) medicine that has high capture section for thermal neutrons 10 B(n,α) 7 Li neutron capture and nuclear fission reaction generation 4 He (He) 7 Li two heavy charged particles, the average energy of the two charged particles is about 2.33MeV, the particles have high linear transfer (Linear Energy Transfer, LET) and short range characteristics, the linear energy transfer and range of alpha particles are 150 keV/mum and 8 μm respectively 7 The Li heavy charged particles are 175 keV/mum and 5μm, the total range of the two particles is approximately equal to one cell size, so that the radiation injury caused to organisms can be limited at the cell level, and when boron-containing medicaments are selectively gathered in tumor cells, the purpose of killing the tumor cells locally can be achieved on the premise of not causing too great injury to normal tissues by matching with a proper neutron source.
Whether the neutron source of the boron neutron capture treatment is from nuclear reaction of charged particles of a nuclear reactor or an accelerator and a target, the generated mixed radiation field is that the beam contains neutrons and photons with low energy to high energy; for boron neutron capture treatment of deep tumors, the more radiation content, except for epithermal neutrons, the greater the proportion of non-selective dose deposition of normal tissue, and therefore the less radiation that will cause unnecessary doses. In addition to the air beam quality factor, in order to better understand the dose distribution of neutrons in the human body, the present invention uses a head mathematical prosthesis model for dose calculation and uses the prosthesis beam quality factor as a design reference for neutron beams, as will be described in detail below.
The international atomic energy organization (IAEA) gives five air beam quality factor suggestions for neutron sources for clinical boron neutron capture treatment, and the five suggestions can be used for comparing the advantages and disadvantages of different neutron sources and serve as reference bases for selecting neutron production paths and designing beam shaping bodies. These five suggestions are as follows:
epithermal neutron beam flux Epithermal neutron flux>1x 10 9 n/cm 2 s
Fast neutron contamination Fast neutron contamination<2x 10 -13 Gy-cm 2 /n
Photon pollution Photon contamination<2x 10 -13 Gy-cm 2 /n
The ratio thermal to epithermal neutron flux ratio of thermal neutron to epithermal neutron flux is less than 0.05
Neutron current to flux ratio epithermal neutron current to flux ratio >0.7
Note that: the epithermal neutron energy region is between 0.5eV and 40keV, the thermal neutron energy region is less than 0.5eV, and the fast neutron energy region is more than 40keV.
Epithermal neutron beam flux:
the neutron beam flux and the boron-containing drug concentration in the tumor together determine the clinical treatment time. If the concentration of the boron-containing medicament in the tumor is high enough, the requirement on the neutron beam flux can be reduced; conversely, if the boron-containing drug concentration in the tumor is low, a high flux epithermal neutron is required to administer a sufficient dose to the tumor. IAEA requires a epithermal neutron beam flux of greater than 10 epithermal neutrons per square centimeter per second 9 The neutron beam at this flux can generally control the treatment time to within one hour for current boron-containing drugs, and short treatment times can more effectively utilize the limited residence time of boron-containing drugs within tumors in addition to advantages for patient positioning and comfort.
Fast neutron contamination:
since fast neutrons cause unnecessary normal tissue doses, which are positively correlated with neutron energy, as a matter of pollution, the fast neutron content should be minimized in the neutron beam design. Fast neutron contamination is defined as the fast neutron dose accompanied by a unit epithermal neutron flux, with IAEA recommended for fast neutron contamination as less than 2x 10 -13 Gy-cm 2 /n。
Photon pollution (gamma ray pollution):
gamma rays belong to strong penetrating radiation and can cause dose deposition of all tissues on a beam path in a non-selective way, so that the reduction of the gamma ray content is also an essential requirement for neutron beam design, the gamma ray pollution is defined as the gamma ray dose accompanied by unit epithermal neutron flux, and the proposal of IAEA on the gamma ray pollution is smallAt 2x 10 -13 Gy-cm 2 /n。
Ratio of thermal neutron to epithermal neutron flux:
because of high thermal neutron attenuation speed and poor penetrating capacity, most of energy is deposited on skin tissues after entering a human body, and thermal neutrons are required to be used as neutron sources for boron neutron capture treatment for superficial tumors such as melanoma and the like, so that the thermal neutron content is required to be reduced for deep tumors such as brain tumors and the like. The IAEA to thermal neutron to epithermal neutron flux ratio is recommended to be less than 0.05.
Neutron beam to flux ratio:
the ratio of the neutron beam current to the flux represents the directionality of the beam, the larger the ratio is, the better the front direction of the neutron beam is, the high front direction neutron beam can reduce the surrounding normal tissue dose caused by neutron divergence, and the treatable depth and the posture setting elasticity are improved. IAEA is recommended to have a neutron beam to flux ratio greater than 0.7.
Fig. 1 shows a neutron therapeutic apparatus 100 according to the present application, wherein the neutron therapeutic apparatus 100 includes a beam shaping body 10, a neutron generating section 11 provided in the beam shaping body 10, a tube bundle 20 for transporting an ion beam P from an accelerator 200 to the neutron generating section 11, and a deflection magnet 30 for changing the direction of transport of the ion beam P in the tube bundle 20. The beam shaping body 10 includes a retarder 12 and a reflector 13 surrounding the retarder 12, and the neutron generating portion 11 is embedded in the retarder 12 (see fig. 2). The beam shaping body 10 has a beam outlet, and a collimator 40 is arranged on the end face where the beam outlet is located.
Referring to fig. 3, the neutron treatment device 100 further includes an irradiation space 50 for irradiating the irradiated body M and a support frame 60 for supporting the beam shaping body 10. The support frame 60 includes a first support portion 61, and the first support portion 61 is provided with a first rail 611, and the first support portion 61 and the first rail 611 are configured as an arc structure with the same center for convenience in manufacturing. In other embodiments, the first support 61 and the first rail 611 may be configured in other shapes to provide more variation in the position of the beam shaper 10 relative to the irradiation space 50, which is not specifically described herein. The beam shaping body 10 is held on the first rail 611 and is movable in the first rail 611, so that the neutron treatment device irradiates the irradiated body M in the irradiation space 50 at different angles.
Referring to fig. 4 to 6, as an example, the first rail 611 is provided on the circular arc outer surface of the first support 61. The irradiation space 50 is located below the first supporting portion 61, and the first track 611 is concavely formed from the circular arc outer surface of the first supporting portion 61 to form a receiving space 612 that is communicated with the irradiation space 50. The outer surface of the reflector 13 extends with holding parts 131 at two sides of the beam shaping body 10, the holding parts 131 are held in the first rail 611 and move along the first rail 611, and the collimator 40 extends from the accommodating space 612 in the irradiation space 50. Of course, for the miniaturization of the entire neutron treatment device, instead of providing a holding portion on the surface of the reflector, the end surface of the beam shaping body provided with the collimator 40 may be engaged with the first rail 611, and the end surface may be directly held on the first rail 611 and the neutron treatment device 100 may irradiate the irradiated body M at different angles by the movement of the end surface in the first rail 611.
As another embodiment, the irradiation space 50 may not be disposed under the first support 61, but on one side of the first support 61, and a holding portion extending from the beam shaping body 10 to be located on one side of the beam shaping body 10, the holding portion being held in the first rail 611 and moving in the first rail 611. At this time, the beam outlet of the beam shaping body 10 faces the irradiation space 50', and when the beam shaping body 10 moves in the first trajectory 611, the neutron treatment device 100 can irradiate the irradiation target (not shown) in the irradiation space 50' at different angles.
The first rail may be further provided at a front end surface of the first support portion. The holder extends from the outer surface of the reflector to one side of the beam shaping body, the holder being held in and moving in a first track. Of course, there are many other embodiments, for example, a fixing portion is not provided, but a part of the reflector is directly fixed in the first track to serve as a fixing portion, so long as the reflector can be moved along the first track to achieve different angles of irradiation of the irradiated object in the irradiation space by the neutron treatment device, which will not be described herein.
The tube bundle 20 has an axis, and the tube bundle 20 includes a first tube bundle 21 fixed to the accelerator 200, a third tube bundle 22 fixed to the neutron production section 11, and a second tube bundle 23 connected between the first tube bundle 21 and the third tube bundle 22. The axes include a first axis I of the first tube bundle 21 and a second axis II of the second tube bundle 23. The deflection magnet 30 includes a first deflection magnet 31 and a second deflection magnet 32. One end of the first tube bundle 21 is connected to the accelerator 200, and the other end is connected to the first deflection magnet 31; one end of the second tube bundle 23 is connected to the first deflection magnet 31, and the other end is connected to the second deflection magnet 32; one end of the third tube bundle 22 is connected to the second deflection magnet 32, and the other end is connected to the neutron generator 11 and between the neutron generator 11 and the second tube bundle 23. The beam shaper 10 is rotatable about a first axis I of the first tube bundle 21 or a second axis II of the second tube bundle 23 to change the angle of illumination of the beam shaper 10 with respect to an illuminated body in the illumination space 50. The direction of the ion beam P in the first tube bundle 21 is deflected by the first deflection magnet 31 and then transferred to the second tube bundle 23, the direction of the ion beam P in the second tube bundle 23 is deflected by the second deflection magnet 32 and then transferred to the third tube bundle 22, and the ion beam P in the third tube bundle 22 is transferred to the neutron generator 11 to generate a neutron beam required for irradiation of the irradiation object by the neutron therapeutic apparatus 100.
The support frame 60 is further provided with a second support 62 above the first support 61, the second deflection magnet 32 being held to the second support 62, the second support 62 being provided with a second track 621 allowing the second deflection magnet 32 to move with the beam shaping body 10. The specific structure of the second rail 621 may refer to the structure of the first rail 611 for holding the beam shaping body 10 and allowing the beam shaping body 10 to move, which is not described in detail herein. The second support portion 62 may be provided behind the first support portion 61 as shown in fig. 9.
The beam shaping body 10 moves in the first track 611 according to different irradiation angles required by the irradiated body, when the beam shaping body 10 rotates around the first axis I, the third tube bundle 22 moves along with the beam shaping body 10, and the second deflection magnet 32 moves in the second track 621 under the driving of the movement of the third tube bundle 22, so that the neutron treatment device 100 irradiates the irradiated body in the irradiation space 50 at different angles. Of course, the beam shaping body 10 may also be arranged to rotate about the second axis II of the second tube bundle 23, so that a multi-angle irradiation of the beam shaping body 10 with the irradiated body in the irradiation space 50 is also possible, which will not be described in detail here.
As shown in fig. 7 and 8, a first included angle a1 is formed between the first tube bundle 21 and the second tube bundle 23, a second included angle a2 is formed between the second tube bundle 23 and the third tube bundle, the sizes of the first included angle a1 and the second included angle a2 can be changed, and any one or two of the first included angle a1 and the second included angle a2 can be provided with a structure with changeable angle according to actual needs, so as to reduce the limitation of the irradiation angle of the beam integral body 10.
The neutron treatment device 100 further includes a third support 63 for fixing the first deflection magnet 31, and the third support 63 may be directly provided on the support frame 60 as shown in fig. 9 or may be directly fixed on the ground as shown in fig. 3.
The following describes the rotation process of the entire neutron treatment device in the embodiments of the present application in detail.
Firstly, determining an irradiation direction according to the specific condition of an irradiated body, moving the beam shaping body 10 to a position capable of performing the angle irradiation in a first track 611 according to the determined irradiation direction, and positioning the third tube bundle 22 after moving to a specific position along with the beam shaping body 10;
then, the deflection directions of the first deflection magnet 31 and the second deflection magnet 32 are determined based on the position of the first tube bundle 21, the position of the third tube bundle 22, and the position of the second tube bundle 23. Since the position of the first tube bundle 21 is fixed and the position of the third tube bundle 22 is determined according to the movement position of the beam shaping body 10, the second tube bundle 23 is located between the first tube bundle 21 and the third tube bundle 22 and the second deflection magnet 32 and the first deflection magnet 31 are both fixed at one end of the tube bundle 20, so that the position of the second tube bundle 23 may be any position that can be obtained in the space after the determination of the positions of the first tube bundle 21 and the third tube bundle 22, and the deflection directions of the first deflection magnet 31 and the second deflection magnet 32 are determined according to the determined positions of the three tube bundles, so that the ion beam P transmitted from the accelerator 200 is transmitted to the neutron generating section 11.
The direction of the ion beam P in the first tube bundle 21 is changed by the first deflection magnet 31 and then transferred to the second tube bundle 23, the direction of the ion beam P in the second tube bundle 23 is changed by the second deflection magnet 32 and then transferred to the third tube bundle 22, and the ion beam P in the third tube bundle 22 is directly irradiated to the neutron generator 11 to generate a neutron beam, which irradiates the irradiated object.
It should be noted that, although the slow beam shaping body itself has a shielding function, a shielding body for shielding the irradiation space may be additionally provided in order to obtain a better shielding effect in the irradiation treatment of the irradiated body. Particularly, in the case where the first rail 611 is recessed from the surface of the first support 61 to form a receiving space 612 in communication with the irradiation space 50 (see fig. 5), a gap is formed between the beam shaping body 10, the receiving space 612, and the irradiation space 50, which on the one hand affects the overall aesthetic appearance of the neutron treatment device, and on the other hand also increases the leakage of radiation during irradiation, so that it is necessary to provide a shielding body 70 (70') that covers the receiving space 612 and shields the irradiation space 50 during irradiation.
The specific structure of the shielding 70 (70 ') is described below in connection with the illustration, said shielding 70 (70') being capable of moving with the movement of the beam shaper 10 and shielding the irradiation space 50.
Referring to fig. 10 and 11, the shield 70 includes two shields 71 that can be extended or retracted in the direction of movement of the beam shaping body 10. The shielding members 71 are respectively located at two sides of the beam shaping body 10, and one end of each shielding member 71 is connected to the supporting frame 60, and the other end is connected to the beam shaping body 10.
The shielding member 71 is composed of a plurality of shielding portions 72 that are fastened end to end, the end portions of the shielding portions 72 fastened to each other are provided with fastening portions 73, and the fastening portions 73 can move on the surface of the shielding portions 72 and fasten to adjacent fastening portions. When the shield 71 is contracted, the shield portions 72 are stacked one by one; when the shield 71 is spread, the shield portions 72 are spread one by one and are held to each other so that the adjacent two shield portions 72 are positioned. The shield 71 is partially unfolded, that is to say the partial shield 72 is unfolded as shown in fig. 10, the partial shields 72 still being stacked together, in any case the shields 72 being stretched or stacked with the movement of the beam shaping body 10.
As shown in fig. 12 and 13, when the beam shaping body 10 moves relative to the first support frame 61, the shielding members 71 on one side of the beam shaping body 10 are gradually stacked by being contracted, and the shielding members 71 on the other side of the beam shaping body 10 are gradually elongated by being expanded. When the shielding parts 72 are stacked together, a portion of the shielding member 71 away from the irradiation space 50 is connected to the beam shaping body 10, and a portion of the shielding member 71 close to the irradiation space 50 is connected to the support frame 60.
As described above, the first rail 611 is provided in an arc shape, and each individual shielding portion 72 is also provided in an arc shape in the present embodiment to achieve a better shielding effect. After the shielding portions 72 are spread one by one, the whole shielding member 71 is arc-shaped.
In order to minimize leakage of radiation during irradiation, the height H1 of the receiving space 612 is set to be not less than the thickness (not numbered) of the shield 70, the thickness of the shield 70 being the total thickness of the plurality of shield portions 72 stacked together. And, the width W2 of the shielding body 70 is not smaller than the width W1 of the accommodating space 612.
Fig. 15 illustrates another embodiment of a shield 70' of the present application. The shield 70' is connected to both sides of the beam shaper 10 and forms the irradiation space 50 as described above. The shielding body 70' is integrally provided and is rotatable about the support 61 (as shown in fig. 16) with the movement of the beam shaping body 10, thereby shielding the irradiation space 50. In the present embodiment, the shielding body 70 'is accommodated in the accommodating space 612, and the width W2' of the shielding body 70 'is not smaller than the width W1 of the accommodating space 612, however, the thickness of the shielding body 70' may be set to be not greater than the height H1 of the accommodating space 612.
The shielding body 70 (70') is provided to shield the radiation leaking from the beam shaping body 10, and to cover the space formed among the irradiation space 50, the accommodation space 612, and the beam shaping body 10, thereby facilitating the overall appearance.
A shield wall (not shown) that can be moved away from the shield or moved close to the shield and can be abutted against the shield may be provided on the outer side of the shield. When the shielding wall is far away from the shielding body, the beam shaping body 10 rotates on the supporting frame 60 according to actual requirements to obtain a proper irradiation position, and the shielding body moves along with the movement of the beam shaping body 10 and always covers the irradiation space 50 to shield the irradiation space 50; when the beam shaper 10 is in the proper irradiation position, the shielding wall approaches and abuts against the shielding body, the beam shaper 10 irradiates the irradiation space 50, and the shielding body shields the irradiation space 50.
The shielding wall provides supporting force for the shielding body on one hand and shares part of supporting force born by the supporting frame; on the other hand, the shielding body can shield the radiation generated in the irradiation process at the same time of shielding, so that the shielding effect is enhanced.
The arc shape described herein includes not only a certain arc shape on a circle, but also an arc-like shape formed by connecting a plurality of straight lines, regular or irregular curves.
It will be understood that terms such as "having," "including," and "comprising," as used herein, do not preclude the presence or addition of one or more other ingredients or combinations thereof.
Although embodiments of the invention have been disclosed above, they are not limited to the use listed in the specification and embodiments. It can be applied to various fields suitable for the present invention. Additional modifications will readily occur to those skilled in the art. Therefore, the invention is not to be limited to the specific details and illustrations shown and described herein, without departing from the general concepts defined in the claims and their equivalents.
Claims (10)
1. The neutron treatment device is characterized by comprising a beam shaping body, a neutron generating part arranged in the beam shaping body, a tube bundle for transmitting an ion beam to the neutron generating part, a deflection electromagnet for changing the transmission direction of the ion beam and a collimator, wherein the beam shaping body comprises a retarder and a reflector wrapped around the retarder, the neutron generating part generates neutrons after being irradiated by the ion beam, the retarder decelerates neutrons generated by the neutron generating part to an epithermal neutron energy region, the reflector guides the deflected neutrons back to improve the neutron intensity in the epithermal neutron energy region, the collimator intensively irradiates neutrons generated by the neutron generating part, the neutron treatment device is provided with an irradiation space for irradiating an irradiated body, the beam shaping body is connected with a shielding body for shielding radiation leaked from the beam shaping body, the shielding body comprises at least two shielding pieces capable of stretching or shrinking along the movement direction of the beam shaping body, the shielding pieces are positioned on two sides of the beam shaping body, and each shielding piece is connected with one end of the beam shaping body along with the irradiation space, and the shielding body is connected with one end of the shielding body along with the irradiation space.
2. The neutron treatment device of claim 1, wherein the surface of the support frame is concavely provided with a containing space communicated with the irradiation space, a gap is formed among the beam shaping body, the containing space and the irradiation space, and the shielding body covers the gap.
3. The neutron treatment device of claim 2, wherein the shield on one side of the beam shaping body expands and the shield on the other side of the beam shaping body contracts as the beam shaping body moves.
4. The neutron treatment device of claim 3, wherein the shielding member is composed of a plurality of shielding portions which are held one by one, and when the shielding member is spread out, the shielding portions are spread out one by one to be held one by one; when the shield is contracted, the shield portions are stacked one by one.
5. The neutron therapeutic device of claim 4, wherein the end portions of the shielding portions which are mutually locked are provided with locking portions which are movable on the surface of the shielding portions and are mutually locked and positioned with the adjacent locking portions.
6. The neutron treatment device of claim 4, wherein the shielding portions are arranged in an arc shape, and the shielding member is in an arc shape when the shielding portions are stretched one by one.
7. The neutron treatment device of claim 3, wherein the height of the containing space is not less than the thickness of the shielding body, and the width of the shielding body is not less than the width of the containing space.
8. The neutron treatment device of claim 2, wherein the shield is connected to both sides of the beam shaping body and is integrally provided, and when the beam shaping body moves, the shield is rotatable together with the beam shaping body around the support frame and always covers the beam shaping body, the accommodation space and the irradiation space to form a gap therebetween.
9. The neutron treatment device of claim 8, wherein the width of the shield is not less than the width of the containment space.
10. The neutron therapeutic device of claim 2, wherein the supporting frame comprises a first supporting portion, the first supporting portion is provided with a first track, the beam shaping body is fixed on the first track, the first track is concavely arranged from the surface of the first supporting portion to form the accommodating space communicated with the irradiation space, the first supporting portion is arranged in an arc shape, and the first track is arranged in an arc shape with the same center as the first supporting portion.
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610517977.XA CN107569778B (en) | 2016-07-04 | 2016-07-04 | Neutron therapeutic device |
| PCT/CN2016/110409 WO2018006551A1 (en) | 2016-07-04 | 2016-12-16 | Neutron therapy device |
| RU2019102398A RU2707651C1 (en) | 2016-07-04 | 2016-12-16 | Apparatus for neutron therapy |
| EP16908055.3A EP3456382B1 (en) | 2016-07-04 | 2016-12-16 | Neutron therapy device |
| JP2018568672A JP6754847B2 (en) | 2016-07-04 | 2016-12-16 | Neutron therapy device |
| TW106207221U TWM549081U (en) | 2016-07-04 | 2017-05-19 | Neutron therapy device |
| TW106207223U TWM558633U (en) | 2016-07-04 | 2017-05-19 | Neutron therapy device |
| US16/213,023 US10744345B2 (en) | 2016-07-04 | 2018-12-07 | Neutron therapy apparatus |
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| CN201610517977.XA CN107569778B (en) | 2016-07-04 | 2016-07-04 | Neutron therapeutic device |
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| CN107569778B true CN107569778B (en) | 2024-03-22 |
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