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CN107347998A - A kind of baby milk powder for strengthening nutrient absorption and immunity of organisms and preparation method thereof - Google Patents

A kind of baby milk powder for strengthening nutrient absorption and immunity of organisms and preparation method thereof Download PDF

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Publication number
CN107347998A
CN107347998A CN201710687015.3A CN201710687015A CN107347998A CN 107347998 A CN107347998 A CN 107347998A CN 201710687015 A CN201710687015 A CN 201710687015A CN 107347998 A CN107347998 A CN 107347998A
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China
Prior art keywords
lactose
base
milk
parts
sugared
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CN201710687015.3A
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Chinese (zh)
Inventor
张岩春
潘丽娜
欧阳琰桦
戴智勇
莫红卫
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AUSNUTRIA DAIRY (CHINA) Co Ltd
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AUSNUTRIA DAIRY (CHINA) Co Ltd
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Priority to CN201710687015.3A priority Critical patent/CN107347998A/en
Publication of CN107347998A publication Critical patent/CN107347998A/en
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C21/00—Whey; Whey preparations
    • A23C21/04—Whey; Whey preparations containing non-milk components as source of fats or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C21/00—Whey; Whey preparations
    • A23C21/06—Mixtures of whey with milk products or milk components
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C21/00—Whey; Whey preparations
    • A23C21/08—Whey; Whey preparations containing other organic additives, e.g. vegetable or animal products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C21/00—Whey; Whey preparations
    • A23C21/10—Whey; Whey preparations containing inorganic additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1522—Inorganic additives, e.g. minerals, trace elements; Chlorination or fluoridation of milk; Organic salts or complexes of metals other than natrium or kalium; Calcium enrichment of milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1526—Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1528—Fatty acids; Mono- or diglycerides; Petroleum jelly; Paraffine; Phospholipids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/156—Flavoured milk preparations ; Addition of fruits, vegetables, sugars, sugar alcohols or sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/158—Milk preparations; Milk powder or milk powder preparations containing additives containing vitamins or antibiotics

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses a kind of baby milk powder for strengthening nutrient absorption and immunity of organisms, raw material includes following components：Lactose, desalted whey powder, skimmed milk power, composite plant oil, the ester of 1,3 2 oleic acid, 2 palmitic acid three, WPC, milk albumin peptide or sheep whey protein peptide, mineral substance premix, arachidonic acid, human milk oligosaccharides, soybean lecithin, docosahexaenoic acid, water soluble vitamin premix, nucleotides, liposoluble vitamin premix etc..Using milk powder obtained by the present invention, effect is：Added while the ester of 1,3 two oleic acid, 2 palmitic acid three, human milk oligosaccharides and milk albumin peptide or sheep whey protein peptide, play synergy, can promote to digest and assimilate nutriment, healthy intestinal health, while improve immunity.Invention additionally discloses a kind of preparation method of above-mentioned milk powder, using the method disclosed in the present, effect is：Processing step is simplified, and technological parameter is easily controlled, and is adapted to large-scale production.

Description

A kind of baby milk powder for strengthening nutrient absorption and immunity of organisms and preparation method thereof
Technical field
The present invention relates to field of food, and in particular to a kind of baby milk powder for strengthening nutrient absorption and immunity of organisms and Its preparation method.
Background technology
Breast milk is the food for being best suitable for infant nutrient demand, but because a variety of causes, many mothers cannot be guaranteed breast milk Abundance is fed, it is necessary to be fed using baby formula milk powder.
Although the existing dispensed food for baby of in the market is the milk after adding nutrient again as base-material using ox, sheep breast more Powder, can be that the nutrition for providing abundance of the infant of different phase ensures.But contain abundant albumen in ripe breast milk Matter, structuring fatty (containing a high proportion of Sn-2 palmitic acids Structure grease), mineral matter, vitamin, carbohydrate (mainly contain Lactose and abundant oligosaccharide) etc..
Modern nutriology is relatively generally acknowledged, and breast milk is the optimal food of infant, and baby humanized milk powder Golden standard.Can be with digestive some enzymes and immune protein and peptides in breast milk but can not cover in baby milk powder Etc. the beneficiating ingredient for being beneficial to intestinal beneficial bacterium.Found by research：Human milk oligosaccharides (HMO) in human milk contain in people's colostrum Measure and be：22-23g/L, during maturation is newborn：12-13g/L, the addition of human milk oligosaccharides, makes baby formula milk powder be more nearly mother Breast.
The ester (structured lipid OPO) of 1,3 two oleic acid 2- palmitic acids three is actually a kind of structuring fat, passes through enzyme process Ester-exchange technology simulates breast milk lipid molecular structure, 2 palmitate ratios is up to 40-50%, horizontal closer to breast milk, addition Structured lipid OPO, lipid nutrition ingredient draws can be promoted, improve energy utilization and reduce constipation.And in mammal Anatomical research during find that its distal small intestine has substantial amounts of small peptide aggregation, the experiment of continuation shows, mammal absorbs The form of protein is mainly to be absorbed with small peptide.Small intestine is exactly the main absorption place of small peptide, turning for peptide on intestinal mucosa be present Carrier, have transhipment fast, power consumption is low, the characteristics of being not easy saturation.The milk albumin peptide or sheep whey protein peptide of addition, can promote Enter the absorption of protein.
Therefore, a kind of baby that constipation and the beneficiating ingredient that nutrient absorption can be strengthened can be reduced to antibacterium, and can is designed Baby formulas milk powder is significant.
The content of the invention
The first object of the present invention, which is to provide one kind, to be included human milk oligosaccharides, structuring fat OPO and peptides etc. and has The enhancing nutrient absorption of beneficial composition and the baby milk powder of immunity of organisms, concrete technical scheme are as follows：
A kind of baby milk powder for strengthening nutrient absorption and immunity of organisms, raw material is included with the following group in terms of parts by weight Point：Lactose 25-33 parts, desalted whey powder 15-20 parts, skimmed milk power 12-37 parts, composite plant oil 16-27 parts, 1,3 2 oleic acid The ester 2.4-9.6 parts of 2- palmitic acids three, WPC 5-9 parts, galactooligosaccharide 0-6 parts, FOS 0-6 parts, ox Whey protein peptide or sheep whey protein peptide 0.01-0.3 parts, mineral substance premix 0.8-1.5 parts, arachidonic acid 0.3-1.8 parts, Human milk oligosaccharides 0.1-2.5 parts, soybean lecithin 0.2-1.2 parts, docosahexaenoic acid 0.2-1.0 parts, water soluble vitamin are pre- Batch mixing 0.1-0.4 parts, nucleotides 0.018-0.05 parts, liposoluble vitamin premix 0.01-0.06 parts, taurine 0.01- 0.04 part and l-cn 0.01-0.02 parts；
Each component parts by weight sum is 100 parts.
Preferable in above technical scheme, the human milk oligosaccharides are 2'- rock algae bases lactose, 3- rock algae bases lactose, 3'- salivas Liquid lactose, 3'- saliva base-N- acetyl lactosamines, 6'- salivas lactose, 6'- saliva base-N- acetylation lactose amine, 3'- salivas base- 3- rock algae bases lactose, two sialyllactoses, single rock algae base, single saliva base lactose, lactose-N- trisaccharides, lacto-N-tetraose, lactose- The new tetroses of N-, saliva base lacto-N-tetraose a, saliva base lacto-N-tetraose b, saliva base lacto-N-tetraose c, saliva base lactose- N- tetroses d, double saliva base lacto-N-tetraoses, lactose-bis- rocks algae tetrose, single saliva base, single rock algae base lacto-N-tetraose, single saliva Liquid-based, single rock algae base lacto-N-neotetraose, three rock algae base lacto-N-neotetraose I, lactose-N- rock algae pentasaccharides I, lactose-N- rocks Algae pentasaccharides II, lactose-N- rock algae pentasaccharides III, lactose-N- rock algae pentasaccharides VI, lactose-N- rock algae pentasaccharides V, saliva base-lactose-N- Rock algae pentasaccharides V, the new rock algae pentasaccharides I of lactose-N-, lactose-N- six be sugared, the sugar of p- lactose-N- six, new six sugar of lactose-N-, rock algae base- P- lactose-N- six is sugared, double rock algae base-p- lactose-N- six are sugared, single sugared, single rock algae base lactose-N- of saliva base-lactose-N- new six Six sugared, single six sugared I of rock algae base lactose-N-, single six sugared III of rock algae base lactose-N-, double six sugared a of rock algae base lactose-N-, double rock algaes Six sugared b of base lactose-N-, double six sugared c of rock algae base lactose-N-, sugared, the double rock algae base lactose-N- new six of double rock algae base lactose-N- new six Sugared b, double rock algae base-p- lactose-N- six be sugared, single saliva base, and double new six sugared, double rock algae base-p- lactose of rock algae base lactose-N-- New six sugar of N-, the sugar of three rock algae base lactose-N- six, the sugar of three rock algae bases-p- lactose-N- six, two rock algaes of lactose-N-, six sugared I, lactose- The new new double rock algae bases six of the sugar of double rock algae bases six, lactose-N- of bis- rock algaes of N-, six sugared II, two rock algaes of lactose-N-, six sugared IV, lactose-N- At least one of new six sugar of sugared II, p- lactose-N-, new ten sugar of lactose-N- and three rock algae bases-sugar of iso- lactose-N- ten.
Preferable in above technical scheme, content of the human milk oligosaccharides in milk powder is 1g/Kg-25g/Kg.
Preferable in above technical scheme, content of the OPO in milk powder is 24g/Kg-96g/Kg。
It is preferable in above technical scheme, in the milk albumin peptide or sheep whey protein peptide：Molecular weight is less than 1000 It is 75%-85% that the component of dalton, which accounts for total mass fraction,；The preparation method of the milk albumin peptide or sheep whey protein peptide It is：It is raw material by bovine whey protein concentrate or sheep WPC, through enzyme hydrolysis, separates the lactalbumin peptide composition of acquisition, Wherein：It is 75%-85% that molecular weight accounts for total mass fraction less than the peptide of 1000 dalton；By spray drying, bovine whey is produced Protein peptides or sheep whey protein peptide.
It is preferable in above technical scheme, the water soluble vitamin premix, liposoluble vitamin premix and mineral Within the scope of the content of matter premix meets national standard, and according to formula requirement addition.
It is as follows using the enhancing nutrient absorption of the present invention and the baby milk powder of immunity of organisms, effect：
(1) present invention is based on breast milk composition is studied, by adding human milk oligosaccharides (HMO), 1,3 two oleic acid 2- palms Acid glycerol three ester (structured lipid OPO) and milk albumin peptide or sheep whey protein peptide, allow baby formula milk powder to be more nearly mother Breast, help infant to maintain intestinal health state, and make nutrition preferably by infant's intestinal absorption.
(2) aliphatic acid plays critically important effect during infant growth, can be as main supply The material of energy, structured lipid OPO are abbreviation of 1, the 3- positions containing the triglycerides of 2 oleic acid, 2- positions containing 1 palmitic acid, and it is more easy to In digesting and assimilating for aliphatic acid and calcium nutriment, constipation is reduced, mitigates enteron aisle burden, health environment is built for enteron aisle.
(3) human milk oligosaccharides can be advantageous to the breeding of beneficial bacterium in enteron aisle, and suppressing harmful bacteria, (including streptococcus pneumonia exists Interior a variety of harmful bacterias), prevent the enteron aisle of pathogen from sticking, so as to reduce stomach inflammation and enterogastritis caused by bacterial infection The incidence of disease of property disease, strengthen immunity.
(4) it is small that molecular weight is made using ox or sheep WPC as raw material in milk albumin peptide or sheep whey protein peptide In the peptide of 1000 dalton, finally it is added in a manner of dry-mixed in formula, effect is：A, milk albumin peptide or sheep lactalbumin Peptide can be directly entered blood circulation as protein source and be utilized by body；B, just enteron aisle can be repaired well in enteron aisle to be damaged Cell, and rise in value beneficial to beneficial bacterium；C, the raising of enzymatic activity in enteron aisle can be induced, and then proposes the development of small intestine digestive function Before, promote digesting and assimilating for nutriment.
(5) 1,3 two ester of oleic acid 2- palmitic acids three, human milk oligosaccharides and milk albumin peptides or sheep whey protein peptide Add simultaneously, play collaboration facilitation, formula milk of the invention can both promote to digest and assimilate nutriment, beneficial Intestinal health, it is beneficial to improve immunity of organisms again.
(6) present invention also added other nutriments, such as docosahexaenoic acid, arachidonic acid, vitamin premix Expect (including water miscible and fat-soluble), mineral substance premix etc. so that enhancing nutrient absorption of the invention and immunity of organism Nutrition in the baby milk powder of power is formed closer to breast milk, achieves preferable technique effect.
The second object of the present invention is the infant's milk for providing a kind of above-mentioned enhancing nutrient absorption and immunity of organisms The preparation method of powder, comprises the following steps：
Step 1: dispensing：Skimmed milk power, desalted whey powder, lactose, WPC, oligomeric gala are weighed by proportioning Sugar, FOS, human milk oligosaccharides, mineral substance premix, water soluble vitamin premix, taurine and l-cn, it is molten It is in 40 DEG C -55 DEG C of water in 3-4 times of mixed material gross weight and temperature, is well mixed and obtains the first mixed material；
Either, the fresh milk that the skimmed milk power as needed for proportioning is made is subjected to pasteurize, degreasing is obtained after fractionation of fatty Milk；Desalted whey powder, lactose, WPC, galactooligosaccharide, FOS, human milk oligosaccharides, ore deposit are weighed by proportioning It is mixed that material premix, water soluble vitamin premix, taurine and l-cn are well mixed to obtain first with skim milk Compound material；
Step 2: batch mixing homogeneous：Composite plant oil, the ester of 1,3 2 oleic acid 2- palmitic acids three, soybean phosphorus are weighed by proportioning Fat, docosahexaenoic acid, arachidonic acid and liposoluble vitamin premix, put with the first mixed material obtained by step 1 Enter to carry out homogeneous in high pressure homogenizer to obtain the second mixed material；
Step 3: sterilization：Second mixed material obtained by step 2 is sterilized；
Step 4: concentration：The second mixed material after step 3 sterilizes is concentrated, obtains the 3rd mixture Material；
Step 5: spray drying：3rd mixed material is spray-dried to obtain the 4th mixed material；
Step 6: fluidized bed drying：4th mixed material is subjected to fluidized bed drying and cooled down, obtains original washing powder material；
Step 7: batch mixing：Milk albumin peptide or sheep whey protein peptide and nucleotides are weighed by proportioning, adds the base Stirred in powder material, produce the baby formula milk powder of enhancing nutrient absorption and immunity of organisms；
Either, the docosahexaenoic acid adds with arachidonic acid in step 2 without wet method, but in step Formula requirement is pressed with dry-mixed work with the powder form of docosahexaenoic acid grease powder and arachidonic acid oil powder in rapid seven Skill is added, wherein：The mass content of docosahexaenoic acid is 8-10% in docosahexaenoic acid grease powder, arachidonic acid Arachidonic mass content is 8-10% in oil powder.
It is preferable in above technical scheme, in the step 1：The temperature of pasteurize is 70 DEG C -75 DEG C, pasteurize Time be the 18-30 seconds；
In the step 2：Homogenizing temperature is 50 DEG C -72 DEG C, homogenization pressure 10-20MPa；
In the step 3：Sterilization temperature is 85 DEG C -95 DEG C, and sterilizing time is the 15-30 seconds；
In the step 4：Concentrated using double-effect falling film evaporator, the first effect vacuum is 30-42kPa, evaporation temperature Spend for 70 DEG C -75 DEG C；Second effect vacuum is 60-70kPa, and evaporating temperature is 45 DEG C -52 DEG C；3rd mixed material is concentrated into 15-25 ° of B é (Baume degrees)；This step is concentrated using multiple-effect falling film evaporator, to save the energy, is reached heat energy and is fully reclaimed Purpose.
In the step 5：Pressure be 12-20MPa, EAT is 150 DEG C -190 DEG C and temperature of outgoing air is 70 It is spray-dried under the conditions of DEG C -90 DEG C；
In the step 7：Stirring uses three-dimensional dry-mixed machine, and mixing time is 15-20 minutes, reaches mixing intensity and adds up to 700-730 turns/batch, it is therefore an objective to mixes to than more uniform.
Using the preparation method of the present invention, have the following effects that：Processing step is simplified, and technological parameter is easily controlled, and is adapted to The features such as large-scale production.
In addition to objects, features and advantages described above, the present invention also has other objects, features and advantages. Below with reference to embodiment, the present invention is further detailed explanation.
Embodiment
Embodiments of the invention are described in detail below in conjunction with specific embodiment, but the present invention can be according to right It is required that the multitude of different ways for limiting and covering is implemented.
Embodiment 1：
A kind of baby formula milk powder for strengthening nutrient absorption and immunity of organisms, raw material includes lactose in terms of parts by weight 31 parts, 18 parts of desalted whey powder, 19.7 parts of skimmed milk power, composite plant oily 16 parts, the ester of 1,3 2 oleic acid 2- palmitic acids three 2.4 parts, 5 parts of WPC, 2 parts of galactooligosaccharide, 3 parts of FOS, 0.01 part of milk albumin peptide, mineral matter premix 0.9 part of material, 1.0 parts of arachidonic acid, 0.1 part of human milk oligosaccharides, 0.3 part of soybean lecithin, 0.3 part of docosahexaenoic acid, water 0.2 part of soluble vitamin premix, 0.02 part of nucleotides, 0.03 part of liposoluble vitamin premix, 0.03 part of taurine and 0.01 part of l-cn.
The human milk oligosaccharides are by saliva base lacto-N-tetraose c, three rock algae base lacto-N-neotetraose I, single rock algae base breast Six sugared I of sugar-N- and double six sugared b of rock algae base lactose-N- are according to 1：1：1：1 quality proportioning mixes.
The composite plant oil is by high oleic sunflower oil 30%, soybean oil 25%, coconut oil 30% and rapeseed oil 15% mixes (in terms of mass fraction)；In the high oleic sunflower oil：The mass fraction that oleic acid accounts for total fatty acids is 80%.
The mineral substance premix is made up of the material mixture of following percentage by weight：Calcium carbonate 30%, potassium chloride 29%, Magnesium sulfate 18%, sodium citrate 10%, tricalcium phosphate 10%, ferrous sulfate 2.2%, zinc sulfate 0.7%, copper sulphate 0.0811%th, manganese sulfate 0.01%, KI 0.007% and sodium selenite 0.0019%.
The water soluble vitamin premix is made up of the material mixture of following percentage by weight：L-AA sodium 50%th, Choline Chloride 24.9%, inositol 18%, niacinamide 3%, D-VB5 calcium 1.1%, Bio 1.1%, cyanocobalamin 0.8%th, thiamine hydrochloride 0.5%, puridoxine hydrochloride 0.3%, riboflavin 0.18% and folic acid 0.12%.
The liposoluble vitamin premix is made up of the material mixture of following percentage by weight：Dl- α-D-α-tocopherol acetate 61%th, axerophtholum aceticum 22%, Vitamin D3 12% and phytondione 5%.
The preparation method of the baby milk powder of above-mentioned enhancing nutrient absorption and immunity of organisms, specifically includes following steps：
Step 1: dispensing：It (is 72 DEG C in temperature that the fresh milk that the skimmed milk power as needed for proportioning is made is carried out into pasteurize Under the conditions of sterilize 20 seconds), obtain skim milk after fractionation of fatty；Desalted whey powder, lactose, condensed whey egg are weighed by proportioning In vain, galactooligosaccharide, FOS, human milk oligosaccharides, mineral substance premix, water soluble vitamin premix, taurine and L-cn is well mixed to obtain the first mixed material with skim milk；
Step 2: batch mixing homogeneous：Composite plant oil, the ester of 1,3 2 oleic acid 2- palmitic acids three, 22 are weighed by proportioning Carbon acid, arachidonic acid, soybean lecithin and liposoluble vitamin premix, put with the first mixed material obtained by step 1 Enter to carry out homogeneous in high pressure homogenizer to obtain the second mixed material；Wherein：Homogenizing temperature is 65 DEG C, homogenization pressure 15MPa；
Step 3: sterilization：Second mixed material obtained by step 2 is sterilized, wherein：Sterilization temperature is 85 DEG C, sterilization Time is 15 seconds；
Step 4: concentration：The second mixed material after step 3 sterilizes is concentrated, obtains the 3rd mixture Material；Wherein：Concentrated using double-effect falling film evaporator, the first effect vacuum is 39kPa, and evaporating temperature is 72 DEG C；Second effect Vacuum is 68kPa, and evaporating temperature is 50 DEG C；3rd mixed material is concentrated into 18 ° of B é；
Step 5: spray drying：3rd mixed material is spray-dried to obtain the 4th spray drying powdery material, tool Body is：Pressure is 16MPa, EAT is 170 DEG C and temperature of outgoing air be 85 DEG C under the conditions of be spray-dried；
Step 6: fluidized bed drying：4th spray drying powdery material is subjected to fluidized bed drying and cools down (control material Middle water content is 3.0wt%), obtain original washing powder material；
Step 7: batch mixing：Milk albumin peptide and nucleotides are weighed by proportioning, adds in the original washing powder material and stirs (stirring uses three-dimensional dry-mixed machine, and mixing time is 20 minutes), produce infant's milk of enhancing nutrient absorption and immunity of organisms Powder.
The baby milk powder of above-mentioned enhancing nutrient absorption and immunity of organisms can also be packed, be specifically：Using Vacuum nitrogen or carbon dioxide controlled atmospheric packing, form minimum sales unit product (such as canned or packed or other monomers packaging shape The product of formula).
Above-mentioned enhancing nutrient absorption should meet national related to the testing result of the baby formula milk powder of immunity of organisms Product standard requirement.
Embodiment 2：
A kind of baby milk powder for strengthening nutrient absorption and immunity of organisms, its difference from Example 1 are：Baby children Youngster's milk powder raw material in terms of parts by weight includes following components：It is 25 parts of lactose, 18 parts of desalted whey powder, 25.59 parts of skimmed milk power, multiple Close 16 parts of vegetable oil, 3.86 parts of 1,3 2 oleic acid 2- palmitic acids, three ester, 5 parts of WPC, galactooligosaccharide 0.05 Part, 0.05 part of FOS, 0.8 part of mineral substance premix, arachidonic acid oil powder (arachidonic acid ARA mass content For 10%) 3 parts, 0.1 part of human milk oligosaccharides, 0.2 part of soybean lecithin, docosahexaenoic acid grease powder (docosahexaenoic acid DHA mass content for 10%) 2 parts, 0.1 part of water soluble vitamin premix, milk albumin peptide 0.2,0.02 part of nucleotides, 0.01 part of 0.01 part of liposoluble vitamin premix, 0.01 part of taurine and l-cn.
2nd, the skimmed milk power in the present embodiment is finished product, without being made using fresh milk；The human milk oligosaccharides are lactose-N- Newly the sugared, p- lactose-N- of double rock algae bases six new six is sugared by two rock algaes, six sugared IV, lactose-N-, lactose-N- new ten is sugared and three rock algaes The sugar of base-iso- lactose-N- ten is according to 1：1：2：1：3 quality proportioning mixes.
3rd, the present embodiment vitamin, mineral matter proportioning are as follows：
The mineral substance premix is made up of the material mixture of following percentage by weight：Calcium carbonate 25%, potassium chloride 25%, Magnesium sulfate 17%, sodium citrate 12%, tricalcium phosphate 18%, ferrous sulfate 2.2%, zinc sulfate 0.7%, copper sulphate 0.082%, Manganese sulfate 0.01%, KI 0.007% and sodium selenite 0.001%.
The water soluble vitamin premix is made up of the material mixture of following percentage by weight：L-AA sodium 45%th, Choline Chloride 25.7%, inositol 20%, niacinamide 4.8%, D-VB5 calcium 1.8%, Bio 1%, cyanocobalamin 0.5%th, thiamine hydrochloride 0.5%, puridoxine hydrochloride 0.5%, riboflavin 0.05% and folic acid 0.15%.
The liposoluble vitamin premix is made up of the material mixture of following percentage by weight：Dl- α-D-α-tocopherol acetate 70%th, axerophtholum aceticum 15%, Vitamin D3 7% and phytondione 8%.
4th, docosahexaenoic acid and arachidonic acid add in step 2 without wet method, but with two in step 7 Dodecahexaene acid lipid powder (docosahexaenoic acid DHA mass contents are 10%), arachidonic acid oil powder (arachidonic Sour ARA mass contents are added for powder form 10%) by formula requirement with dry mixing process.
The testing result of the above-mentioned enhancing nutrient absorption of detection of the present embodiment milk powder and the baby milk powder of immunity of organisms National products standards requirement should be met, and performance is close with embodiment 1.
Embodiment 3：
A kind of baby milk powder for strengthening nutrient absorption and immunity of organisms, its difference from Example 1 are：
Baby milk powder raw material in terms of parts by weight includes following components：28 parts of lactose, 20 parts of desalted whey powder, defatted milk 14.4 parts of powder, 16 parts of composite plant oil, 9.6 parts of 1,3 2 oleic acid 2- palmitic acids, three ester, 5 parts of WPC, sheep whey 0.1 part of protein peptides, 0.05 part of galactooligosaccharide, 0.98 part of FOS, 1.0 parts of mineral substance premix, arachidonic acid 1.2 Part, 1.7 parts of human milk oligosaccharides, 1.2 parts of soybean lecithin, 0.2 part of docosahexaenoic acid, 0.4 part of water soluble vitamin premix, 0.02 part of 0.05 part of nucleotides, 0.06 part of liposoluble vitamin premix, 0.04 part of taurine and l-cn.
2nd, the human milk oligosaccharides are that 6'- salivas base-N- acetylation lactose amine and three rock algae base lacto-N-neotetraose I are pressed According to 1：4 quality proportioning mixes.
3rd, the present embodiment vitamin, mineral matter proportioning are as follows：
The mineral substance premix is made up of the material mixture of following percentage by weight：Calcium carbonate 28%, potassium chloride 28%, Magnesium sulfate 20%, sodium citrate 12.2%, tricalcium phosphate 9%, ferrous sulfate 1.8%, zinc sulfate 0.8%, copper sulphate 0.135%th, manganese sulfate 0.05%, KI 0.012% and sodium selenite 0.003%.
The water soluble vitamin premix is made up of the material mixture of following percentage by weight：L-AA sodium 49.1%th, Choline Chloride 26%, inositol 18%, niacinamide 3%, D-VB5 calcium 1%, Bio 1%, cyanocobalamin 0.6%, salt Allithiamine element 0.45%, puridoxine hydrochloride 0.45%, riboflavin 0.1% and folic acid 0.3%.
The liposoluble vitamin premix is made up of the material mixture of following percentage by weight：Dl- α-D-α-tocopherol acetate 60%th, axerophtholum aceticum 20%, Vitamin D3 12% and phytondione 8%.
The testing result of humanized milk powder obtained by the present embodiment meets relevant national standard requirement, and performance and embodiment 1 It is close.
Comparative example 1：
The baby formula milk powder difference from Example 1 of this comparative example is：Without human milk oligosaccharides；Degreasing Milk powder dosage is 19.8 parts.
Comparative example 2：
The baby formula milk powder difference from Example 2 of this comparative example is：Without 1,3 2 oleic acid 2- palms Acid glycerol three ester and human milk oligosaccharides；Skimmed milk power dosage is 29.55 parts.
The oleic acid of 1,3- bis- (is free of using embodiment 1-3, comparative example 1-2 and prior art baby formula milk powder The ester of 2- palmitic acids three, human milk oligosaccharides and milk albumin peptide or sheep whey protein peptide) tested：
1st, subjects：SPF level health male SD rat (14 age in days), 29.39 ± 1.89g of average weight.
2nd, test method：The experiment of rat is fed using different formulations milk powder, measures rat production performance and nutriment Digestibility, it is specifically：
2.1st, 14 age in days rats are randomly divided into six groups by body weight, every group 16, feed baby children obtained by embodiment 1-3 respectively Youngster's formula milk (experimental group 1-3), baby formula milk powder obtained by comparative example 1-2 (contrast experiment organizes 1-2) and existing (blank group, it is oligomeric that signified blank group is free from OPO, human milk to the baby milk powder of technology Sugar, the baby milk powder of milk albumin peptide (or sheep whey protein peptide).During experiment, each group animal presses rat nutritional need mark Standard, quantitative bowel lavage, quantitative water compensating early stage (before 21 days), later stage free water (after 21 days), five weeks test periods.
For measuring the mouse of blood calcium, then eye socket takes blood in 3 minutes after last is fed.
2.2nd, Testing index and method, it is specifically：National feed industry mark is respectively adopted in crude protein, crude fat, aliphatic acid The GB/T 6432-1994 of Zhun Hua technical committees customization, GB/T 6433-2006, GB/T 21514-2008 methods；Blood calcium contains Measurement is pressed surveys serum calcium levels with EDTA titrations；Measurement data is represented with average ± standard deviation, soft using SPSS18.00 Part bag carries out data processing.Experimental result is analyzed using single factor test variance.With p≤0.05, mean difference has conspicuousness, has Statistical significance.
3rd, result of the test, Details as Follows (X represents average value, behalf amplitude)：
3.1st, to the influence of rat production performance, table 1 is referred to：
Influence statistical form (X ± s) of the 1 each formula milk of table to rat production performance
Group/parameter Average daily gain (g) Feedstuff-meat ratio
Blank group 3.64±0.85 1.45±0.32
Experimental group 1 6.33±0.15 2.25±0.41
Experimental group 2 6.0±0.12 2.85±0.45
Experimental group 3 6.12±0.17 2.55±0.12
Contrast experiment's group 1 5.94±0.15 2.21±0.07
Contrast experiment's group 2 5.93±0.12 2.20±0.96
It can be seen from table 1：
Analysis of variance and multiple comparative test, between blank group and experimental group, between blank group and contrast experiment's group with And having significant difference between experimental group and contrast experiment's group, contrast experiment organizes between 1-2 and equal nothing between experimental group 1-3 Significant difference, illustrate problems with：(1) blank group, experimental group and contrast experiment's group can be sent out for the growth of mouse well Nutrition needed for offer is provided；(2) it is a kind of in addition human milk oligosaccharides, structured lipid OPO and milk albumin peptide or sheep whey protein peptide Or several can mouse growth be promoted to develop；(3) using human milk oligosaccharides, structured lipid OPO and the milk albumin peptide of the present invention Or the technical scheme of sheep whey protein peptide triplicity, positive effect are better than prior art (blank group) and single use scheme (contrast experiment organizes 1-2), it is seen that the combination of three achieves unexpected effect.
3.2nd, to the influence of the nutritive digestibility of rat, table 2 is referred to：
The calculation formula of nutritive digestibility is as follows：Nutrient apparent digestibility %=(is sought in nutrient intake-excrement Foster plain just content)/nutrient intake × 100%.
Influence statistical form (X ± s) of the 2 each formula milk of table to rat nutritive digestibility
Group/parameter Crude protein (%) Crude fat (%) Aliphatic acid (%)
Blank group 82.12±0.88 85.33±0.12 79.22±0.3
Experimental group 1 92.15±0.80 93.45±0.12 93.12±0.51
Experimental group 2 93.27±0.66 94.10±0.1 94.32±0.31
Experimental group 3 91.05±0.03 94.25±0.17 93.2±0.5
Contrast experiment's group 1 85.16±0.44 88.14±0.15 87.14±0.4
Contrast experiment's group 2 84.11±0.12 85.24±0.2 86.3±0.44
It can be seen from table 2：
Analysis of variance and multiple comparative test, between blank group and experimental group, between blank group and contrast experiment's group with And having significant difference between experimental group and contrast experiment's group, contrast experiment organizes between 1-2 and equal nothing between experimental group 1-3 Significant difference, illustrate problems with：The crude protein, crude fat and aliphatic acid apparent digestibility that blank group feeds mouse are substantially low In experimental group and contrast experiment's group, and contrast experiment organizes each nutrient digestibility and is significantly lower than experimental group, it is possible thereby to illustrate, The combination of human milk oligosaccharides, structured lipid OPO and milk albumin peptide or sheep whey protein peptide three are improved and promoted well The digestion and absorption of above nutrient.
3.3rd, to the influence of the blood parameters of rat, Details as Follows：
(1) to the influence of the blood calcium of rat, table 3 is referred to：
Influence statistical form (X ± s) of the 3 each formula milk of table to rat blood calcium
Group/parameter Blood calcium (mmol/L)
Blank group 1.33±0.03
Experimental group 1 2.23±0.34
Experimental group 2 2.10±0.84
Experimental group 3 2.22±0.1
Contrast experiment's group 1 2.0±0.34
Contrast experiment's group 2 1.98±0.34
It can be seen from table 3：
Analysis of variance and multiple comparative test, hence it is evident that blank group feed mouse blood calcium concentration be substantially lower than experimental group and Contrast experiment's group；And contrast experiment's group is less than experimental group.It fact proved that experimental group nursing mouse can preferably play to assimilate food In calcium.
By contrasting blank group, experimental group and contrast experiment's group it is known that blank group Nutrients Absorption is worst, experimental group Most preferably.It is possible thereby to illustrate, the milk powder of this formula can play a part of strengthening Nutrients Absorption.
(2) to the influence of the routine blood indexes of rat, it is specifically：Blood, cellanalyzer zootype are taken through femoral artery Pre-dilution method determines 19 physical signs of rat blood, leucocyte WBC, neutrophil leucocyte Neu, lymphocyte Lym, intermediate value cell Mid, neutrophil leucocyte percentage Neu%, lymphocyte percentage Lym%, intermediate value cell percentages Mid%；Red blood cell RBC, Hemoglobin concentration Hb, packed cell volume HCT, mean corpuscular volume (MCV) MCV, mean corpuscular hemoglobin MCH are average red thin Extracellular hemoglobin concentration MCHC, RDW coefficient of variation RDW-CV, RDW standard deviation RDW-SD；Number of platelets PLT, mean platelet volume MPV, MPW PDW, thrombocytocrit PCT.Refer to table 4th, table 5 and table 6：
Influence statistical form (X ± s) of the 4 each formula milk of table to rat routine blood indexes 1
Influence statistical form (X ± s) spss of 5 each formula milk of table to rat routine blood indexes 2
Influence statistical form (X ± s) of the 6 each formula milk of table to rat routine blood indexes 3
Group/parameter N PLT(×109/L) MPV(fL) PDW (%) PCT (%)
Blank group 10 650.25±120.50 7.68±0.55 15.75±0.21 0.65±0.21
Experimental group 1 10 714.65±155.13 6.89±0.56 16.45±1.32 0.58±0.13
Experimental group 2 10 952.10±152.32 7.85±0.21 15.42±0.10 0.71±0.11
Experimental group 3 10 758.11±163.12 8.41±1.23 16.32±0.15 0.60±0.32
Contrast experiment's group 1 10 749.68±14.65 7.66±1.56 18.65±1.23 0.68±0.21
Contrast experiment's group 2 10 801.56±16.89 7.19±0.29 17.65±1.05 0.67±0.11
(3) to the influence of the trilute (T3), thyroxine (T4) of rat, table 7 is referred to：
Influence statistical form (X ± s) of the 7 each formula milk of table to the T3 and T4 of rat
Group/parameter N T3 T4
Blank group 10 0.55±0.08 40.05±1.63
Experimental group 1 10 1.28±0.12 59.12±5.41
Experimental group 2 10 1.24±0.44 62.47±4.12
Experimental group 3 10 2.01±0.40 60.71±6.73
Contrast experiment's group 1 10 0.81±0.11 41.81±3.47
Contrast experiment's group 2 10 0.97±0.10 44.74±2.14
Analysis of variance and multiple comparative test, experimental group and blank group, contrast experiment organize contrast, RBC in rat blood, Hb, HCT, MCV, MCH significantly increase, and have statistical significance；The horizontal obvious reductions of RDW-CV.On the basis of more than, enter one Step carries out general pathologic examination discovery：
Liver：All murine liver tissue structural integrities, lobuli hepatis fall through substantially, and with being normally no different.
Kidney：Envelope is complete, there is dense connective tissue composition；Envelope hypopallium is multiple to be dispersed in glomerulus, clear in structure；Kidney Tubular epithelial aligned orderly, it is uniform in size, show no obvious abnormalities.
Duodenum：Clear in structure, fine hair is complete, marshalling, and lamina propria is without congestion and edema, blank group and contrast experiment Group mouse duodenal section has no obvious cell infiltration.But the visible goblet cell of mouse duodenal of experimental group increases. The mucus of goblet cell secretion has protection and a mucosedative effect, its quantity number reflect the health status of intestinal mucosa, It is the abnormal sensitive instruction of intestinal mucosal, goblet cell increases prompting mucous membrane of small intestine immunologic function and improved.
In summary, compared with blank group and contrast experiment's group, the effect of experimental group is：(1) it can more promote body blood red Albumen increases, and T3 and T4 levels improve, and goblet cell increases, and enhances immunity of organisms；(2) can more increase Nutrients Absorption and raising immunity of organisms.
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, for the skill of this area For art personnel, the present invention can have various modifications and variations.Within the spirit and principles of the invention, that is made any repaiies Change, equivalent substitution, improvement etc., should be included in the scope of the protection.

Claims (8)

  1. A kind of 1. baby milk powder for strengthening nutrient absorption and immunity of organisms, it is characterised in that the raw material bag in terms of parts by weight Include following components：Lactose 25-33 parts, desalted whey powder 15-20 parts, skimmed milk power 12-37 parts, composite plant oil 16-27 parts, 1, The ester 2.4-9.6 parts of 3 two oleic acid 2- palmitic acids three, WPC 5-9 parts, galactooligosaccharide 0-6 parts, FOS 0- 6 parts, milk albumin peptide or sheep whey protein peptide 0.01-0.3 parts, mineral substance premix 0.8-1.5 parts, arachidonic acid 0.3- 1.8 parts, human milk oligosaccharides 0.1-2.5 parts, soybean lecithin 0.2-1.2 parts, docosahexaenoic acid 0.2-1.0 parts, water soluble vitamin Raw plain premix 0.1-0.4 parts, nucleotides 0.018-0.05 parts, liposoluble vitamin premix 0.01-0.06 parts, taurine 0.01-0.04 parts and l-cn 0.01-0.02 parts；
    Each component parts by weight sum is 100 parts.
  2. A kind of 2. baby milk powder for strengthening nutrient absorption and immunity of organisms according to claim 1, it is characterised in that The human milk oligosaccharides are 2'- rock algae bases lactose, 3- rock algae bases lactose, 3'- salivas lactose, 3'- saliva base-N- acetyl lactose Amine, 6'- salivas lactose, 6'- saliva base-N- acetylation lactose amine, 3'- saliva base -3- rock algae bases lactose, two sialyllactoses, Single rock algae base, single saliva base lactose, lactose-N- trisaccharides, lacto-N-tetraose, lacto-N-neotetraose, saliva base lacto-N-tetraose A, saliva base lacto-N-tetraose b, saliva base lacto-N-tetraose c, saliva base lacto-N-tetraose d, double saliva base lactose-N- four Sugar, lactose-bis- rocks algae tetrose, single saliva base, single rock algae base lacto-N-tetraose, single saliva base, single rock algae base lactose-N- new four Sugar, three rock algae base lacto-N-neotetraose I, lactose-N- rock algae pentasaccharides I, lactose-N- rock algae pentasaccharides II, lactose-N- rock algae pentasaccharides III, lactose-N- rock algae pentasaccharides VI, lactose-N- rock algae pentasaccharides V, saliva base-lactose-N- rock algae pentasaccharides V, the new rock algaes of lactose-N- Pentasaccharides I, lactose-N- six are sugared, p- lactose-N- six is sugared, lactose-N- new six is sugared, rock algae base-p- lactose-N- six is sugared, double rock algaes Base-p- lactose-N- six is sugared, sugared, the single rock algae base lactose-N- of single sugared, single rock algae base lactose-N- six of saliva base-lactose-N- new six Six sugared I, single six sugared III of rock algae base lactose-N-, double six sugared a of rock algae base lactose-N-, double six sugared b of rock algae base lactose-N-, double rock algaes Sugared, the double new six sugared b of rock algae base lactose-N- of six sugared c of base lactose-N-, double rock algae base lactose-N- new six, double rock algae base-p- lactose- N- six is sugared, single saliva base, and new six sugar of double new six sugared, double rock algae base-p- lactose-N- of rock algae base lactose-N-, three rock algae base lactose- The sugar of N- six, the sugar of three rock algae bases-p- lactose-N- six, two rock algaes of lactose-N-, six sugared I, two rock algaes of lactose-N-, six sugared II, lactose-N- Two rock algaes, six sugared IV, lactose-N- newly the sugar of double rock algae bases six, lactose-N- newly new six sugar of double six sugared II of rock algae base, p- lactose-N-, At least one of new ten sugar of lactose-N- and three rock algae bases-sugar of iso- lactose-N- ten.
  3. 3. the baby milk powder of a kind of enhancing nutrient absorption and immunity of organisms according to claim 1-2 any one, Characterized in that, content of the human milk oligosaccharides in milk powder is 1g/Kg-25g/Kg.
  4. A kind of 4. baby milk powder for strengthening nutrient absorption and immunity of organisms according to claim 3, it is characterised in that Content of the ester of bis- oleic acid 2- palmitic acids of 1,3- three in milk powder is 24g/Kg-96g/Kg.
  5. A kind of 5. baby milk powder for strengthening nutrient absorption and immunity of organisms according to claim 3, it is characterised in that In the milk albumin peptide or sheep whey protein peptide：Molecular weight accounts for total mass fraction less than the component of 1000 dalton 75%-85%；The preparation method of the milk albumin peptide or sheep whey protein peptide is：By bovine whey protein concentrate or sheep whey Protein concentrate is raw material, through enzyme hydrolysis, separates the lactalbumin peptide composition of acquisition, wherein：Molecular weight is less than 1000 dalton It is 75%-85% that peptide composition, which accounts for total mass fraction,；By spray drying, milk albumin peptide or sheep whey protein peptide are produced.
  6. A kind of 6. baby milk powder for strengthening nutrient absorption and immunity of organisms according to claim 3, it is characterised in that The content of the water soluble vitamin premix, liposoluble vitamin premix and mineral substance premix meet national standard scope it It is interior.
  7. A kind of 7. system of the baby milk powder of enhancing nutrient absorption as claimed in any one of claims 1 to 6 and immunity of organisms Make method, it is characterised in that comprise the following steps：
    Step 1: dispensing：Skimmed milk power, desalted whey powder, lactose, WPC, galactooligosaccharide, low is weighed by proportioning Fructooligosaccharides, human milk oligosaccharides, mineral substance premix, water soluble vitamin premix, taurine and l-cn, are dissolved in mixing 3-4 times of material gross weight and temperature are in 40 DEG C -55 DEG C of water, are well mixed and obtain the first mixed material；
    Either, the fresh milk that the skimmed milk power as needed for proportioning is made is subjected to pasteurize, skim milk is obtained after fractionation of fatty； Desalted whey powder, lactose, WPC, galactooligosaccharide, FOS, human milk oligosaccharides, mineral matter are weighed by proportioning Premix, water soluble vitamin premix, taurine and l-cn are well mixed to obtain the first mixture with skim milk Material；
    Step 2: batch mixing homogeneous：By proportioning weigh composite plant oil, the ester of 1,3 2 oleic acid 2- palmitic acids three, soybean lecithin, Docosahexaenoic acid, arachidonic acid and liposoluble vitamin premix, it is put into the first mixed material obtained by step 1 Homogeneous is carried out in high pressure homogenizer and obtains the second mixed material；
    Step 3: sterilization：Second mixed material obtained by step 2 is sterilized；
    Step 4: concentration：The second mixed material after step 3 sterilizes is concentrated, obtains the 3rd mixed material；
    Step 5: spray drying：3rd mixed material is spray-dried to obtain the 4th mixed material；
    Step 6: fluidized bed drying：4th mixed material is subjected to fluidized bed drying and cooled down, obtains original washing powder material；
    Step 7: batch mixing：Milk albumin peptide or sheep whey protein peptide and nucleotides are weighed by proportioning, adds the original washing powder thing Stirred in material, produce the baby formula milk powder of enhancing nutrient absorption and immunity of organisms；
    Either, the docosahexaenoic acid adds with arachidonic acid in step 2 without wet method, but in step 7 In with the powder form of docosahexaenoic acid grease powder and arachidonic acid oil powder by formula requirement added with dry mixing process Add, wherein：The mass content of docosahexaenoic acid is 8-10% in docosahexaenoic acid grease powder, arachidonic acid oil Arachidonic mass content is 8-10% in powder.
  8. 8. preparation method according to claim 7, it is characterised in that
    In the step 1：The temperature of pasteurize is 70 DEG C -75 DEG C, and the time of pasteurize is the 18-30 seconds；
    In the step 2：Homogenizing temperature is 50 DEG C -72 DEG C, homogenization pressure 10-20MPa；
    In the step 3：Sterilization temperature is 85 DEG C -95 DEG C, and sterilizing time is the 15-30 seconds；
    In the step 4：Concentrated using double-effect falling film evaporator, the first effect vacuum is 30-42kPa, and evaporating temperature is 70℃-75℃；Second effect vacuum is 60-70kPa, and evaporating temperature is 45 DEG C -52 DEG C；3rd mixed material is concentrated into 15-25 Baume degrees；
    In the step 5：Pressure is 12-20MPa, EAT is 150 DEG C -190 DEG C and temperature of outgoing air be 70 DEG C - It is spray-dried under the conditions of 90 DEG C；
    In the step 7：Stirring uses three-dimensional dry-mixed machine, and mixing time is 15-20 minutes, reaches mixing intensity and adds up to 700- 730 turns/batch, it is well mixed.
CN201710687015.3A 2017-08-11 2017-08-11 A kind of baby milk powder for strengthening nutrient absorption and immunity of organisms and preparation method thereof Pending CN107347998A (en)

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CN110074209A (en) * 2019-05-16 2019-08-02 福建农林大学 A kind of baby formula milk powder and preparation method thereof containing human milk oligosaccharides and lactoferrin
CN110122865A (en) * 2019-06-03 2019-08-16 哈尔滨工业大学 A kind of supplementary food for infants and preparation method thereof adding breast milk oligosaccharide
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CN108244249A (en) * 2018-01-16 2018-07-06 广州市美素力营养品有限公司 A kind of babies ' formula milk powder and preparation method
CN110074209A (en) * 2019-05-16 2019-08-02 福建农林大学 A kind of baby formula milk powder and preparation method thereof containing human milk oligosaccharides and lactoferrin
CN110122865A (en) * 2019-06-03 2019-08-16 哈尔滨工业大学 A kind of supplementary food for infants and preparation method thereof adding breast milk oligosaccharide
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CN110651830B (en) * 2019-09-29 2023-03-24 澳优乳业（中国）有限公司 Modified milk powder for improving sleep and preparation method thereof
CN112335889A (en) * 2020-09-30 2021-02-09 营家健康科技(广东)有限公司 Compound protein powder for improving human immunity in multiple levels and preparation method thereof
CN115053928A (en) * 2022-06-27 2022-09-16 北京精培医学研究院 Milk powder replacing milk for newborn and preparation method thereof

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Application publication date: 20171117