CN106975026A - The Traditional Chinese medicinal aerosol and kit of a kind of pharynx-clearing throat-benefiting - Google Patents
The Traditional Chinese medicinal aerosol and kit of a kind of pharynx-clearing throat-benefiting Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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Abstract
The invention belongs to the field of Chinese medicines, and in particular to the Traditional Chinese medicinal aerosol and kit of a kind of pharynx-clearing throat-benefiting.The Traditional Chinese medicinal aerosol is made up of the Chinese medicine of following parts by weight:10 20 parts of subprostrate sophora;5 15 parts of Radix Isatidis;5 15 parts of reed rhizome;3 15 parts of honeysuckle;5 15 parts of the capsule of weeping forsythia;5 10 parts of the sterculia seed;58 parts of borneol.The kit is made up of gargle and above-mentioned Traditional Chinese medicinal aerosol, and the gargle is made up of the Chinese medicine of following parts by weight:10 15 parts of emblic;6 10 parts of Exocarpium Citri Rubrum;10 15 parts of honeysuckle;35 parts of Momordica grosvenori;25 parts of peppermint.Beneficial effects of the present invention are that, there is provided a kind of Traditional Chinese medicinal aerosol of new formula, its therapeutic effect preferably, while there is provided the kit being made up of gargle and above-mentioned Alevaire, its therapeutic effect is more preferable than single Alevaire, audio fruit is opened with significant relieving sore-throat.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to the Traditional Chinese medicinal aerosol and kit of a kind of pharynx-clearing throat-benefiting.
Background technology
The Acute and chronic inflammation of bottleneck throat is common clinical, frequently-occurring disease.A pharyngeal part for open airway, normal
In the case of, just with the presence of a variety of viral and bacteriums, simply weaken in the local resistance of internal and external factor effect hypopharynx, it is viral and thin
Bacterium, which is taken advantage of a weak point, causes infection, occurs bacterium largely propagation or the flora imbalance of a certain species in local pathology environment.Even if
Viral pathogenesis also tends to secondary bacterial infection, and the degree of its inflammation can be because of age, immunity, physiological status and viral and bacterium
The difference of virulence and weight differs.For the Acute and chronic inflammation of bottleneck throat, clinical treatment is mostly boiled using antibiotic or Chinese medicine
Clothes.Endo-medicine is systemic administration, its injury to human body is larger and endo-medicine after blood drug concentration is smaller, take effect
Therefore increasing people selection mist is inhaled or treats the Acute and chronic inflammation of bottleneck throat containing the local application's method gargled slowly,.
Fog inhalation therapy is the tension force and inertia on the method destruction decoction surface using ultrasonic wave, produces diameter and is less than 5
The property of medicine droplet of micron, oral, nasal inhalation spreads 3 kinds of forms by inertial collision, gravitational settling and Blang, be deposited on oral cavity,
Throat and air flue at different levels and obtain curative effect (wherein 50% be deposited on mouth and nose pharyngeal).Existing Traditional Chinese medicinal aerosol exist species compared with
The deficiency such as less, function is single and effect is general.It is to reach local application's purpose by sucking the method for gargle containing therapy is gargled,
Therapeutic type gargle includes containing two kinds of Western medicine and Chinese medicine.Wherein the gargle of western medicine composition include Chlorhexidine, borax, chlorohexidene,
Cetylpyridinium Chloride, nitrofurazone, metronidazole and Tinidazole etc., the gargle of these western medicine compositions have significant antibacterial and anti-inflammation functions,
But poor taste, side reaction is more, be also easy to produce drug resistance, particularly easily causes oral cavity and bottleneck throat flora imbalance, should not be used for a long time.
The Chinese medicinal component that the gargle of existing Chinese medicinal ingredients is usually used is more, has certain side effect and does not consider mouthfeel and swallow
Afterwards to the damage of digestive system, at the same existing Chinese medical collutory be substantially it is traditional obtained after adding water to cook, preparation method
It is more complicated.
The content of the invention
The present invention provides the Traditional Chinese medicinal aerosol and kit of a kind of pharynx-clearing throat-benefiting, overcomes Traditional Chinese medicinal aerosol of the prior art
Species is few, function is single and the general deficiency of effect, while the kit provided combines Traditional Chinese medicinal aerosol and gargle,
Overcome the shortcomings of atomization in the prior art with containing gargle be used separately there is provided gargle Chinese medicinal component it is relatively fewer and have medicine food
Homogeneous character, damage is brought containing gargle is swallowed without worry imprudence when gargling to digestive system or body other parts.
The technical scheme that the present invention solves above-mentioned technical problem is as follows:A kind of Traditional Chinese medicinal aerosol of pharynx-clearing throat-benefiting, its by with
The Chinese medicine of lower parts by weight is made:10-20 parts of subprostrate sophora;5-15 parts of Radix Isatidis;5-15 parts of reed rhizome;3-15 parts of honeysuckle;The capsule of weeping forsythia
5-15 parts;5-10 parts of the sterculia seed;5-8 parts of borneol.
As preferred scheme, the Traditional Chinese medicinal aerosol is made up of the traditional Chinese medicinal components of following parts by weight:14 parts of subprostrate sophora;Plate
Blue 8 parts of root;8 parts of reed rhizome;10 parts of honeysuckle;8 parts of the capsule of weeping forsythia;6 parts of the sterculia seed;5 parts of borneol.
Subprostrate sophora is the dry root and rhizome of legume sophora tonkinensis Gapnep, and its is bitter, cold, poisonous, there is clearing heat and detoxicating, detumescence relieving sore-throat
The effect of, be usually used in treatment fiery poison pent up, abscess of throat, it is nonirritant to stomach during general dosage, but as dosage it is excessive, easily cause vomit
Tell, and poisoning can be caused and suffered from diarrhoea, uncomfortable in chest and palpitaition, therefore should not take orally.Radix Isatidis, it is bitter, cold, with clearing heat and detoxicating, cool blood profit
The effect of pharynx, it is usually used in treatment heating pharyngalgia.Reed rhizome, Gan Han can treat cough with lung heat, with clearing heat and eliminating phlegm, promote the production of body fluid to quench thirst
Effect.Honeysuckle is described as clearing heat and detoxicating good medicine from ancient times, and the sweet cold air fragrance of property, clear heat with drugs of sweet flavour and cold nature is fragrant thoroughly up to again without injuring one's stomach
Can eliminating evil, honeysuckle can dispelling wind-heat, be also apt to removing summer-heat blood poison, available for the therapeutic effect to abscess of throat significantly, honeysuckle
It is sweet, do not injure one's stomach and the characteristics of with integration of drinking and medicinal herbs, therefore can be used as the Main Ingredients and Appearance of Traditional Chinese medicinal aerosol, can also be used as Chinese medicine
The composition of gargle.The capsule of weeping forsythia, it is bitter, cool, it is clearing heat and detoxicating, it is usually used in affection of exogenous wind-heat, large carbuncle pyogenic infections, typhoid fever bar can be suppressed in vitro
Bacterium, paratyphosum Bacterium, Escherichia coli, corynebacterium diphtheriae, comma bacillus, streptococcus etc..The sterculia seed, sweet, cold, light weight surname dissipate, above enters
The clear facilitaing lung gas of lung channel, clearing lung and eliminating phlegm, relieving sore-throat opens sound, is larynx section good medicine, but the sterculia seed person's diarrhoea that easily makes deficiency-cold in spleen and stomach, can make blood glucose
Rise and blood pressure reduction, therefore should not take orally.Borneol, pungent hardship, is slightly cold, and the thoughts of returning home, liver, lung channel, Delicate fragrance a surname dissipate are awake with having one's ideas straightened out
God, effect of heat-clearing dissipates poison.
A kind of pharynx-clearing throat-benefiting is provided in order to overcome the shortcomings of independent Chinese herbal aerosol treatment or Chinese medicine containing treatment, the present invention is gargled
Kit, it is made up of Chinese medical collutory and above-mentioned Traditional Chinese medicinal aerosol, and the gargle is made up of the Chinese medicine of following parts by weight:It is remaining
Sweet sub- 10-15 parts;6-10 parts of Exocarpium Citri Rubrum;10-15 parts of honeysuckle;3-5 parts of Momordica grosvenori;2-5 parts of peppermint.The kit both includes Chinese medicine
Alevaire, includes gargle again, can flexibly be selected using nebulae inhalation, made containing gargling treatment or both and combine according to the situation of patient
With the medicine big to digestive system damage as far as possible using poor taste, bitter cold and after swallowing is in the selection for prepare Chinese medicine
The component of medicine Alevaire, and by suitably raw clothes, mouthfeel relatively preferably, be slightly cold and swallow after the medicine small to digestive system damage make
Component is prepared for gargle.
As preferred scheme, above-mentioned gargle is made up of the Chinese medicine of following parts by weight:10 parts of emblic;8 parts of Exocarpium Citri Rubrum;
15 parts of honeysuckle;4 parts of Momordica grosvenori;5 parts of peppermint.
Emblic, sweet, micro-puckery, cool, clearing heat, relieving sore-throat, moistening lung for removing phlegm, promotes the production of body fluid to quench thirst, main cold, fever, cough, pharyngalgia, white
Larynx, dysphoria and thirsty and hypertension etc..Exocarpium Citri Rubrum, pungent, hardship, warm-natured, fragrant odour, the special main many phlegm of lung cold cough.Momordica grosvenori, sweet,
It is cool, made an uproar for lung-fire cough, the disease such as pharyngalgia aphonia.One of peppermint, Chinese conventional Chinese medicine, pungent cool sweating and heat resolving controls influenza, pharynx
Larynx swells and ache.Emblic, Exocarpium Citri Rubrum, honeysuckle, Momordica grosvenori and peppermint are respectively provided with integration of drinking and medicinal herbs feature, therefore prepare gargle with it,
Can be spued after mouth containing certain time can also swallow, without worrying to swallow damage of the gargle to digestive system.
Compared with prior art, the beneficial effects of the invention are as follows:There is provided a kind of new Chinese herbal aerosol agent prescription, it will tool
There are bitter cold or the Chinese medicinal component that should not be taken orally that Alevaire is made, because being nebulae inhalation, belong to external application, therefore taste are protected without compatibility
Chinese medicine, can preferably play the effect that removing summer-heat throat heat toxin, swelling and pain relieving and relieving sore-throat open sound;Present invention also offers a kind of medicament
Box, it combines Alevaire with gargle, by with integration of drinking and medicinal herbs and gargle is made in clearing heat and detoxicating Chinese medicinal component, should
Gargle, containing the also oral administration that can be spued after a period of time is gargled, is hindered in mouth with preferable adjuvant treatment effect and to digestive system
Evil is small, and Alevaire and the gargle of the kit, which are applied in combination, can reach the effect that more preferable pharynx-clearing throat-benefiting opens sound.
Embodiment
Below in conjunction with specific embodiment, the present invention is described in further detail, and example is served only for explaining this hair
It is bright, it is not intended to limit the scope of the present invention.
Embodiment 1
By subprostrate sophora 10g, Radix Isatidis 5g, reed rhizome 5g, honeysuckle 3g, capsule of weeping forsythia 5g;Sterculia seed 5g and borneol 5g mixing and water addings
200mL, decocts 30min, pours out decocting liquid, adds water 200mL, decocts 30min, merges decocting liquid twice and is well mixed, is surpassed
Membrane filtration obtains pharynx-clearing throat-benefiting Alevaire.During treatment, each consumption 10-20mL is daily 1-2 times.
Embodiment 2
By subprostrate sophora 20g, Radix Isatidis 15g, reed rhizome 15g, honeysuckle 15g, capsule of weeping forsythia 15g;Sterculia seed 10g and borneol 8g mixing
Add water 300mL, decocts 30min, pours out decocting liquid, adds water 300mL, decocts 30min, merges decocting liquid twice and is well mixed, enters
Row ultrafiltration membrance filter obtains pharynx-clearing throat-benefiting Alevaire.During treatment, each consumption 10-20mL is daily 1-2 times.
Embodiment 3
By subprostrate sophora 14g, Radix Isatidis 8g, reed rhizome 8g, honeysuckle 10g, capsule of weeping forsythia 8g;Sterculia seed 6g and borneol 5g mixing and water addings
250mL, decocts 30min, pours out decocting liquid, adds water 250mL, decocts 30min, merges decocting liquid twice and is well mixed, is surpassed
Membrane filtration obtains pharynx-clearing throat-benefiting Alevaire.During treatment, each consumption 10-20mL is daily 1-2 times.
Embodiment 4
By subprostrate sophora 10g, Radix Isatidis 8g, reed rhizome 12g, honeysuckle 11g, capsule of weeping forsythia 5g;Sterculia seed 7g and borneol 8g mixing adds
Water 250mL, decocts 30min, pours out decocting liquid, adds water 250mL, decocts 30min, merges decocting liquid twice and is well mixed, carries out
Ultrafiltration membrance filter obtains pharynx-clearing throat-benefiting Alevaire.During treatment, each consumption 10-20mL is daily 1-2 times.
Embodiment 5
Be crushed to after emblic 10g, Exocarpium Citri Rubrum 8g, honeysuckle 15g, Momordica grosvenori 4g and peppermint 5g are mixed in proportion 40 mesh with
On, plus 30-70mL warm water, steep and dissipate, produce gargle, the gargle is combined with the pharynx-clearing throat-benefiting Alevaire that embodiment 3 is obtained,
The as kit of pharynx-clearing throat-benefiting, each kit includes one bottle of gargle and one bottle of Alevaire.The kit is in use, one day
It is interior:Gargle is used 2-3 times, and an osculum, containing 3-5min is gargled, spues or swallow every time;Meanwhile, Alevaire is using 1-2 times, every time
Consumption 10-20mL.
Embodiment 6
Be crushed to after emblic 10g, Exocarpium Citri Rubrum 6g, honeysuckle 10g, Momordica grosvenori 3g and peppermint 2g are mixed in proportion 40 mesh with
On, plus 30-70mL warm water, steep and dissipate, produce gargle, the gargle is combined with the pharynx-clearing throat-benefiting Alevaire that embodiment 3 is obtained,
The as kit of pharynx-clearing throat-benefiting, each kit includes one bottle of gargle and one bottle of Alevaire.The kit is in use, one day
It is interior:Gargle is used 2-3 times, and an osculum, containing 3-5min is gargled, spues or swallow every time;Meanwhile, Alevaire is using 1-2 times, every time
Consumption 10-20mL.
Embodiment 7
40 mesh are crushed to after emblic 10g, Exocarpium Citri Rubrum 10g, honeysuckle 10g, Momordica grosvenori 3g and peppermint 2g are mixed in proportion
More than, plus 30-70mL warm water, steep and dissipate, produce gargle, the pharynx-clearing throat-benefiting Alevaire group that the gargle and embodiment 3 are obtained
Close, as the kit of pharynx-clearing throat-benefiting, each kit includes one bottle of gargle and one bottle of Alevaire.The kit in use,
In one day:Gargle is used 2-3 times, and an osculum, containing 3-5min is gargled, spues or swallow every time;Meanwhile, Alevaire is used 1-2 times,
Each consumption 10-20mL.
Embodiment 8
40 mesh are crushed to after emblic 15g, Exocarpium Citri Rubrum 10g, honeysuckle 15g, Momordica grosvenori 5g and peppermint 5g are mixed in proportion
More than, plus 30-70mL warm water, steep and dissipate, produce gargle, the pharynx-clearing throat-benefiting Alevaire group that the gargle and embodiment 3 are obtained
Close, as the kit of pharynx-clearing throat-benefiting, each kit includes one bottle of gargle and one bottle of Alevaire.The kit in use,
In one day:Gargle is used 2-3 times, and an osculum, containing 3-5min is gargled, spues or swallow every time;Meanwhile, Alevaire is used 1-2 times,
Each consumption 10-20mL.
During in January, 2015 in December, 2016, applicant's tracking have collected the Alevaire for using embodiment 3, embodiment 5
Kit and control group Alevaire to the clinical data of multigroup pharyngitis Case treatment effect, the Alevaire of control group is filled in for ground
The u+ physiological saline 15mL of rice pine 5mg+ gentamicins 80,000, the nebulisation time all same of embodiment 3, embodiment 5 and control group is faced
The specific data of bed treatment are as shown in the table:
In upper table, " recovery from illness " refers to that pharynx is itched, dry throat and general malaise symptom disappear;" effective " refer to pharynx itch, dry throat and complete
Body malaise symptoms are eased;Engineering noise refers to that pharynx is itched, dry throat and general malaise symptom be without improvement.
From upper table data, the pharynx-clearing throat-benefiting Alevaire that the present invention is provided is relative to the conventional use of Alevaire of control group
With more preferable curative effect, cure rate is up to 64.7%, and total effective rate is up to 92.9, the Alevaire of embodiment 3 and control group it is total
Efficient there were significant differences, * P < 0.05;The kit that the present invention is provided, the i.e. corresponding therapeutic effect of embodiment 5 more preferably, are fully recovered
Rate is up to 69.3, and total effectively up to 97.7, compared with the curative effect of control group and the corresponding Alevaire of embodiment 3, there is significance difference
It is different, * P < 0.05.Meanwhile, the clinical data that applicant collects also is shown, using the pharynx-clearing throat-benefiting Alevaire that provides of the present invention and
Kit, takes effect relative comparison group faster, can improve patient quickly the problems such as having a low and deep voice silent caused by pharyngitis, with bright
Aobvious relieving sore-throat opens audio fruit.Do not occur in the case of all use kits substantially because causing stomach using the gargle in it
Intestines are uncomfortable or other uncomfortable situations, and all compositions that the appearance of this effect can give the credit to the gargle in the kit have
There is integration of drinking and medicinal herbs feature, just gentle, similar tea-drinking in the mouthfeel of gargle is reflected using the patient of gargle, nothing is used containing gargling
It is difficult.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and
Within principle, any modification, equivalent substitution and improvements made etc. should be included in the scope of the protection.
Claims (4)
1. a kind of Traditional Chinese medicinal aerosol of pharynx-clearing throat-benefiting, it is characterised in that be made up of the Chinese medicine of following parts by weight:Subprostrate sophora 10-
20 parts;5-15 parts of Radix Isatidis;5-15 parts of reed rhizome;3-15 parts of honeysuckle;5-15 parts of the capsule of weeping forsythia;5-10 parts of the sterculia seed;5-8 parts of borneol.
2. the Traditional Chinese medicinal aerosol of a kind of pharynx-clearing throat-benefiting according to claim 1, it is characterised in that by following parts by weight
Traditional Chinese medicinal components are made:14 parts of subprostrate sophora;8 parts of Radix Isatidis;8 parts of reed rhizome;10 parts of honeysuckle;8 parts of the capsule of weeping forsythia;6 parts of the sterculia seed;Borneol 5
Part.
3. a kind of kit of pharynx-clearing throat-benefiting, it is characterised in that as the Chinese medicine mist described in Chinese medical collutory and claim 1 or 2
Agent is constituted, and the gargle is made up of the Chinese medicine of following parts by weight:10-15 parts of emblic;6-10 parts of Exocarpium Citri Rubrum;Honeysuckle 10-
15 parts;3-5 parts of Momordica grosvenori;2-5 parts of peppermint.
4. the kit of a kind of pharynx-clearing throat-benefiting according to claim 3, it is characterised in that the gargle is by following weight
The Chinese medicine of part is made:10 parts of emblic;8 parts of Exocarpium Citri Rubrum;15 parts of honeysuckle;4 parts of Momordica grosvenori;2-5 parts of peppermint.
Priority Applications (1)
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CN107582903A (en) * | 2017-10-27 | 2018-01-16 | 路望培 | A kind of Traditional Chinese medicinal aerosol for being used to treat pharyngitis |
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