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CN106727870A - It is a kind of to treat compound probiotic washing lotion of yeast infection and preparation method thereof - Google Patents

It is a kind of to treat compound probiotic washing lotion of yeast infection and preparation method thereof Download PDF

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CN106727870A
CN106727870A CN201611090541.3A CN201611090541A CN106727870A CN 106727870 A CN106727870 A CN 106727870A CN 201611090541 A CN201611090541 A CN 201611090541A CN 106727870 A CN106727870 A CN 106727870A
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yeast infection
parts
lactobacillus
washing lotion
compound probiotic
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薛松晓
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Beijing Yike Ecological Science And Technology Research Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
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Abstract

Compound probiotic washing lotion of yeast infection and preparation method thereof is treated the invention provides a kind of.The compound probiotic washing lotion of the treatment yeast infection is made up of following raw material:Mixed bacteria liquid (lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus), mossberry extract (purity 60~80%), glucose, salt and softened water;Its preparation method is:Mixed bacteria liquid, mossberry extract (purity 60~80%), glucose, salt, the softened water of the proportioning are sequentially added in fermentation tank;Fermented 24~72 hours at a temperature of 18~25 degree, be then cooled to 18~24 degree, then fermented 10~12 hours, release bacterium solution, you can packed products.Due to this invention takes above-mentioned technical proposal, compared with prior art, the present invention has the advantages that high activity, high stability, action effect are fast, has no side effect, low cost to treatment yeast infection.

Description

It is a kind of to treat compound probiotic washing lotion of yeast infection and preparation method thereof
Technical field
The invention belongs to compound probiotic biological medicine health product technology field, and in particular to one kind treats yeast infection Compound probiotic washing lotion and preparation method thereof.
Background technology
Saccharomycete is some kinds of fungi (fungi is naturally present within body).But fungi excessively also can in vivo Throw into question.In fact, harmful bacteria can control overall situation, beneficial bacteria is squeezed away.The environment that this can change body is (or raw State), cause infection in the place of harmful bacteria invasion.
Yeast infection it may happen that at any position of body, no matter generating object sex.Female between 16-35 Sui Property be easier vaginal yeast infection occur, but it is it can also happen that in the women of the girl of 10 years old or so or age more than 35 years old With.Vaginal yeast infection is not necessarily what is caused by sexual behaviour.
The cardinal symptom of vaginal yeast infection is exactly lower body sufferings.Other symptoms include that a kind of white of vaginal secretion is tasteless Mucus, more with the scorching hot pain of extra-labia, particularly urination when.It is not that each women above-mentioned symptom can occur, but Generally, if occurring without sufferings, then be just unlikely to be yeast infection.Some women occur secretion in the menstrual period Thing, usual this does not imply that she occurs in that yeast infection phenomenon, especially in the case where there is not sufferings symptom.
Although sufferings are the cardinal symptom of yeast infection, but if never occurring infection before, you may be difficult to do It is clearly what causes your discomfort.This is accomplished by the diagnosis of doctor.After, if occurring similar symptom again, you are with regard to energy The place got to the heart of the problem, or can at least distinguish yeast infection and other illnesss.
The topmost cause of Candida type yeast infection is:Physical fatigue, the not enough or sick body for causing of resting Immunocompetence declines.Recurrent yeast infection is probably to be caused by the diseases such as diabetes or body, spiritual pressure. In addition, the use of the change of antibiotics (including contraceptive), malnutritive and food is also likely to be reason for that. In some rare cases, recurrent yeast infection is the sign of women aids infection virus.If by appropriate Treatment, can't fully recover, and that possibility is just bigger.
Some women the menstrual period end slight yeast infection phenomenon occurs, this be probably by body hormone and PH value change causes.Typically without treatment, it can automatically disappear after the menstrual period terminates for this infection.Pregnant woman is more easy to ferment occur Female bacterium infection.
Weather conditions can also influence the probability of yeast infection.In the weather of hot humid, it is easier to infect.In the winter time, Clothes is blocked up or indoor temperature is too high can all increase the possibility for suffering from yeast infection.
Yeast infection can also be propagated by sexual behaviour.Male is less susceptible to discovery oneself and suffers from yeast infection, because For they any symptom may not occur.If male occurs in that infection symptoms really, then symptom is potentially included:Genitals Upper the occurrence of wetness and the white fash for constantly coming off, while erubescence swell and itch under foreskin.However, immunity degradation the same with women The main cause for causing male's yeast infection is only, rather than sexual behaviour.
The best method for avoiding yeast infection is to avoid sexual behaviour.If cannot avoid, sheath can be provided for you Best protection, it is to avoid yeast infection and other diseases propagated by sexual behaviour, including HlV viruses.There is no unicity The people of object, sheath must be used when there is sexual behaviour, i.e., practised contraception using other method same.If a side is true Yeast infection is examined, the opposing party should also receive treatment.
The drawbacks of medicinal treatment
The non-prescribed medicine for treating yeast infection contains one of following four active component:
(1) butoconazole (Butoconazole Nitrate 3);
(2) clotrimazole (Lotrimin of Gyne mono- etc.);
(3) Miconazole (double chlorobenzene Miconazoles 7);
(4) tioconazole (Vagistat).
These medicines belong to same antibacterial family, and action principle is also identical -- break the cell membrane of candidiasis, Until cell is finally decomposed.United States drug was ratified nitric acid respectively with food control office in December, 1996 and 2 months 1997 Butoconazole 3 and Vagistat become non-prescribed medicine from prescription medicine.Other drugs are then listed in non-prescribed medicine very early.
Although these medicines are all effective, the recurrence rate for treating postoperative infection is very high, there are about half patient 4 weeks after healing Inside just it is reoccurred.And, these medicines also have various side effects.Common but less serious side effect have headache, vagina it is scorching hot, Infection, sufferings, inflammation.And less common side effect have fash, have a sore throat, suffer from abdominal pain, rhinitis, odynuria, night pollakiuria, outer swelling of vulva There is pain when swollen, vaginal dryness, inflammation, pain and sexual behaviour.
Expect there are so many sequelae, perhaps you can query these antibacterials.If a kind of side effects of pharmaceutical drugs and disease Disease is equally fearful in itself, or more fearful, and a quick cost/benefit analysis can definitely provide clear and definite answer:This is not It is worth.
Probiotic therapy
Scientific research has confirmed that, the microorganism energy imbalance occurred in yeast infection be infection pathogenic factor it One.And, it has also been realised that being that microorganism imbalance causes yeast infection, micro- life is caused rather than yeast infection Thing is uneven.It is the quantity for adjusting probiotics in Genitourinary (UGS) to solve this unbalanced unique method.This can be with Realized by several method.
First, the common effect of probiotics in Genitourinary is control harmful microorganism.They body other The work that position is done is also similar:Some compounds are generated, some of which is to retain those probiotics and directly attack harmful The antibacterial material of microorganism.
Secondly, probiotics can also reduce the pH value of Genitourinary.This is critically important, because causing a disease (harmful) microorganism not The environment for liking pH value low as probiotics.Probiotics automatically generates the acidic materials such as lactic acid, so the lactic acid bacteria that is otherwise known as. The presence of which can inherently suppress the generation of pathogen.In fact, harmful bacteria will realize oneself by acidic materials bag Enclose, lose protection, they most die at last.
Again, probiotics can also generate hydrogen peroxide.In Genitourinary, hydrogen peroxide can play cleaning action. Pathogenetic bacteria is very fragile, and probiotics has stronger resistance.As discussed above, this be number it Strive.Which kind of bacterium it is more, it just can win.Here it is wanting probiotic supplemented, their quantity is set to exceed enemy ---- The reason for harmful bacteria.
There is the above, probiotics just can be by Successful utilization in treatment yeast infection.The method of probiotic supplemented it One is exactly the edible Yoghourt containing active microorganism.All the time, this is all a kind of traditional remedies, and we can beg in detail later By.Yoghourt is also used as suppository to use.In fact, can just buy the Lactobacillus acidophilus containing lyophilized in Europe Yoghourt suppository.A large amount of lactic acid bacterias are loaded by lyophilized technology by capsule, target location (such as vagina) is then placed in, at that In capsule can decompose and discharge probiotics.Then, probiotics just constantly grows in body.
Here it is the nature in healthy human body.Probiotics grows in vagina or other Genitourinary positions, supports Imperial harmful microorganism.All profitable probliotics on our internal mucous membranes, they are gathered in the pipeline of body or chamber, directly contact Air (such as the probiotics in vagina) or the food (probiotics such as in colon) that we are eaten.Balance is for some reason And after being broken, the quantity of probiotics is reduced, so as to cause the attachment point in pH value rising, cell to open, pathogenic microorganisms is opened Beginning apposition growth.
It is most common yeast infection phenomenon by the microbial infection of Candida albicans, present let us specially discusses one Descend it.Lactic acid can suppress the growth of Candida albicans mattress as you know, but but Nobody Knows for detailed process.Seemingly three trips Play person --- certain balancing activity is carried out between-lactic acid bacteria, Candida albicans and carbohydrate.We oneself through discussing Above two, then what role carbohydrate plays the part of herein
Carbohydrate has different forms, but their basic chemical component is identical.Their appearance is not It is important, but in order that explanation is simple, it will be assumed that they are all sugar.Sugar is by two kinds of material compositions:Glucose and fructose.Portugal Grape sugar is commonly referred to blood sugar.Most sugars can be decomposed or change into glucose, then be used effectively.To soma, It is not always the case for bacterial cell and yeast cell.Almost all of life entity all likes sugar.The composition of sugar is simpler, more Easily decompose, it is also faster to be eaten and utilized.
How many sugar is strictly controlled at what time for certain part of body because microorganism be likely to will be big Amount sugar misuses in promotion own growth.Here it is the reason for causing yeast infection.In laboratory culture saccharomycete or prebiotic During bacterium, sugar can be usually added to accelerate the growth of bacterium.During to being directly added into pure glucose in bacterium, they are just as placing oneself in the midst of Paradise is the same.But when adding probiotics, the sugar (being referred to as prebiotics) in probiotics will not promote the life of pathogenic microorganisms It is long.And glucose is not prebiotics, even so harmful bacteria can also utilize it.
Having several reasons can cause internal sugar excessive, so as to easily make human body suffer from yeast infection.For example, containing big The diet of amount sugar or carbohydrate can promote the growth of saccharomycete and similar microorganism.People cannot make full use of in vivo for some The illness (such as diabetes) of sugar, can cause internal sugared content severe overweight.Diabetic would generally be big with urine discharge Amount sugar.This creates good living environment, i.e., warm, moist, polysaccharide environment to bacterium and saccharomycete again.
Oneself is through mentioning above, Yoghourt be used to treatment yeast infection oneself through there is many year history.Clinical effectiveness is but very It is complicated:When it is good when it is bad.Investigation is confirmed:Not all dairy produce all containing Bacillus acidi lactici this The microorganism for treating yeast infection most critical is planted, and those active probiotics contained contained by the commodity of Bacillus acidi lactici may Seldom.Make the success of Yoghourt therapy, find one it is in good standing and know how that the manufacturer for selling and processing these products is It is highly important.Specifically, it is exactly manufacturer it is to be understood that how not go to destroy active microorganism.
Processing procedure to probiotics is called " fermentation ".It is even inherently more more important than cultivating probiotics.Probiotics is very Easily influenceed by a series of variable factors:Temperature, moisture, food etc..If there there is no these variable factors in fermentation process It is well controlled, great changes will take place for the property meeting of probiotics, and typically to bad direction change.Therefore, exist In production process, make probiotics growing environment reach it is optimal also it is critical that.
Emphasize again that, it is most important that to contain lactobacillus and Bifidobacterium in probiotics because in Yoghourt two kinds it is main Microorganism ----streptococcus thermophilus and lactobacillus bulgaricus are of short duration organic matters.That is, they will not be implanted into intestines and stomach. Yeast infection is effectively treated, just the Bifidobacteriums such as sum LA-5 intestines and stomach must be together largely constantly input into.
When malignant bacteria is excessive in vivo, you will quickly remove them.The supplies containing probiotics are taken, it is substantial amounts of prebiotic Bacterium can just be delivered directly to infection site.Even if the food for helping against harmful bacteria with other is used together, supplies It is same effective.Mossberry product is often used in treatment urinary tract (UTI s) infection, whether bacterium infection or saccharomycete sense Dye.
Intestines and stomach are an active systems, and the thing of the inside is all the time in change.One of which change is exactly that the inside has Beneficial bacterium and harmful bacteria adhere to and separate constantly.As a result it is exactly disease if the quantity of harmful bacteria exceedes beneficial bacteria Disease or infection.Because beneficial bacteria cannot seize position, so that homeostasis develops towards the direction favourable to them.
Mossberry plays the role of a kind of anti-agglomeration, can suppress the attachment of bacterium.If adding it in probiotics, it can just be helped Probiotics is helped to seize position.Mossberry can suppress the breeding of harmful bacteria, so as to promote the separation of a large amount of harmful bacterias.This is just Space is vacateed to beneficial bacteria in intestinal tract surface, has allowed them to start working.
Certainly, mossberry is it is also possible to separate some beneficial bacterias.In most cases, have tens billion of beneficial Bacterium can enter intestines and stomach by supplies.Supplementing so many microbial organisms can allow balance beneficial towards being conducive to The direction transformation of bacterium.And, mossberry is not absolutely to play effectiveness.It will not make all of bacteria distribution, and Space is simply cleared out on colon, beneficial bacteria can be adhered to.Have these benefits, some joint products, such as probiotics and Mossberry mixture, can turn into the developing direction of probiotic products in future.
It is more on this field as how researcher is to using deepening continuously that probiotics agents treatment saccharomycete is studied New knowledge can be mined out.In fact, probiotics is not only safe and effective, and there are many pairs unlike other non-prescribed medicines Effect.In Europe and Japan, probiotics be used in the treatment to yeast infection be a very universal thing, this Mean that the U.S. and other countries also occur same trend sooner or later.
Therapeutic action of the probiotics to yeast infection of increasing scientific research and clinical trial certificate.
2001《Infectious disease》Studies have reported that the curative effect of probiotics (lactobacillus) in periodical.This article is pointed out, prebiotic Bacterium makes the growth of pathogen be inhibited by 50%--74%.So, patient can attempt it is oral certain through it is clinical confirm it is prebiotic Bacterium replenishers and improve and prevent and treat yeast infection shape using the method for the Yoghourt lavation vagina before sleeping containing specific lactobacillus Into vaginitis.
The Reed at Canadian University of Western Ontario's microbiology and Department of Immunology and Canadian probio research center is won The scientist such as scholar and Andrew's Bruce has carried out the clinical research of more than 20 years to some different lactobacillus, it was confirmed that a few Plant probiotic strain effective to urinary tract infection and reduction urethra pathogenetic bacteria.
In the research carried out specifically designed for 32 women for suffering from bacterial vaginitis, some people is taken daily 1--2 pieces certain probiotics (lactobacillus acidophilus) tablets, and the others then receives placebo treatment.After two weeks, the piece is used The people of agent there are about 77% and be cured, and is cured using the people only 25% of placebo.
In being tested at other one, certain probiotics is taken to wherein 28 women patients, and other 29 then take Use placebo.Checked after one week, it is found that 16 probiotics users have fully recovered, and the number cured in another group is Zero.
It is compared with prior art, of the invention to treatment yeast infection this invention takes above-mentioned technical proposal, with height Activity, high stability, action effect are fast, have no side effect, the advantage of low cost.
The content of the invention
Compound probiotic washing lotion of yeast infection and preparation method thereof is treated it is an object of the invention to provide a kind of.This is washed Compound probiotic in liquid solves the problems, such as yeast infection by antagonism and occupation time process.
A kind of compound probiotic washing lotion for treating yeast infection is provided according to an aspect of the present invention;The compound benefit Raw bacterium washing lotion is made up of following raw material (by weight):20~25 parts of mixed bacteria liquid, mossberry extract (purity 60~ 80%) 15~25 parts, 20~25 parts of glucose, 1~3 part of salt, 220~250 parts of softened water;Wherein described mixed bacteria liquid be by What lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus were mixed, the proportioning between them is 1~2:5~7:7~ 9。
Wherein, the viable bacteria content of the lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus be 16~1,900,000,000/ Milliliter.
A kind of preparation side of the compound probiotic washing lotion for treating yeast infection is provided according to another aspect of the present invention Method, the preparation method is:
Softened water, mossberry extract, glucose, salt, the mixed bacteria liquid of the proportioning are sequentially added in fermentation tank; Fermented 24~72 hours at a temperature of 25~35 degree, be then cooled to 18~24 degree, then fermented 10~12 hours, release bacterium solution, Can packed products.
The present invention has advantages below and beneficial effect:
It is provided by the present invention it is a kind of treat compound probiotic washing lotion of yeast infection and preparation method thereof, it passes through to mix Bacterium solution, mossberry extract (purity 60~80%), glucose, salt and softened water is closed to be mixed by a certain percentage;And lead to Cross antagonism and occupation time process is caused in the problem for the treatment of yeast infection, with high activity, high stability, act on fast, effect Hurry up, have no side effect, the advantage of low cost.
Specific embodiment
To make the object, technical solutions and advantages of the present invention of greater clarity, with reference to specific embodiment, to this Invention is further described.It should be understood that these descriptions are merely illustrative, and it is not intended to limit the scope of the present invention.This Outward, in the following description, the description to known features and technology is eliminated, to avoid unnecessarily obscuring idea of the invention.
A kind of compound probiotic washing lotion for treating yeast infection provided by the present invention, is by the raw material of following weight portion It is made:20~25 parts of mixed bacteria liquid, 15~25 parts of mossberry extract (purity 60~80%), 20~25 parts of glucose, salt 1 ~3 parts, 220~250 parts of softened water;Wherein described mixed bacteria liquid is by lactobacillus bulgaricus, Lactobacillus plantarum and acidophilus breast What bacillus was mixed, the proportioning between lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus is 1~2:5~ 7:7~9.Wherein, the viable bacteria content of lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus is 16~1,900,000,000/milliliter.
A kind of preparation method of compound probiotic washing lotion for treating yeast infection provided by the present invention, the preparation method For:220~250 parts of softened water, 15~25 parts of mossberry extract (purity 60~80%), grape are sequentially added in fermentation tank 20~25 parts of sugar, 1~3 part of salt, 20~25 parts of mixed bacteria liquid;Fermented 24~72 hours at a temperature of 25~35 degree, then dropped Temperature is to 18~24 degree, then ferments 10~12 hours, releases bacterium solution, you can packed products.
Embodiment 1:
The compound probiotic washing lotion for the treatment of yeast infection of the present invention is made up of following raw material (by weight):It is mixed Close 20 parts of bacterium solution, 16 parts of mossberry extract (purity 60~80%), 20 parts of glucose, 1 part of salt, 220 parts of softened water;Wherein The mixed bacteria liquid is mixed by lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus, matching somebody with somebody between them Than being 1:5:7, and the viable bacteria content of the lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus is 1,700,000,000/milli Rise.
The preparation method that the present invention takes is:
Softened water, mossberry extract, glucose, salt, the mixed bacteria liquid of the proportioning are sequentially added in fermentation tank; Fermented 24~72 hours at a temperature of 25~35 degree, be then cooled to 18~24 degree, then fermented 10~12 hours, release bacterium solution, Can packed products.
Embodiment 2:It is of the present invention treatment yeast infection compound probiotic washing lotion be by following raw material (by weight Part) be made:23 parts of mixed bacteria liquid, 20 parts of mossberry extract (purity 60~80%), 23 parts of glucose, 2 parts of salt, softened water 230 parts;Wherein described mixed bacteria liquid is mixed by lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus, it Between proportioning be 1.5:6:8, and the lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus viable bacteria content It is 1,800,000,000/milliliter.
Preparation method is same as Example 1.
Embodiment 3:It is of the present invention treatment yeast infection compound probiotic washing lotion be by following raw material (by weight Part) be made:25 parts of mixed bacteria liquid, 25 parts of mossberry extract (purity 60~80%), 25 parts of glucose, 3 parts of salt, softened water 250 parts;Wherein described mixed bacteria liquid is mixed by lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus, it Between proportioning be 2:7:9, and the viable bacteria content of the lactobacillus bulgaricus, Lactobacillus plantarum and lactobacillus acidophilus is equal It is 1,900,000,000/milliliter.
Preparation method is same as Example 1.
In sum, a kind of compound probiotic washing lotion for treating yeast infection provided by the present invention and its preparation side Method, it passes through mixed bacteria liquid, mossberry extract (purity 60~80%), glucose, salt and softened water and mixes by a certain percentage Conjunction is made;And by antagonism and occupation time process cause treatment yeast infection problem on, with high activity, high stability, Effect is fast, effect is fast, have no side effect, the advantage of low cost.
It should be appreciated that above-mentioned specific embodiment of the invention is used only for exemplary illustration or explains of the invention Principle, without being construed as limiting the invention.Therefore, that is done without departing from the spirit and scope of the present invention is any Modification, equivalent, improvement etc., should be included within the scope of the present invention.Additionally, appended claims purport of the present invention In the whole changes covered in the equivalents for falling into scope and border or this scope and border and repair Change example.

Claims (5)

1. a kind of compound probiotic washing lotion for treating yeast infection, it is characterised in that the treatment yeast infection it is compound Probiotics is made up of the raw material of following weight portion:20~25 parts of mixed bacteria liquid, 15~25 parts of mossberry extract, glucose 20 ~25 parts, 1~3 part of salt, 220~250 parts of softened water;Wherein described mixed bacteria liquid is by lactobacillus bulgaricus, plant breast What bacillus and lactobacillus acidophilus were mixed, the lactobacillus bulgaricus, matching somebody with somebody between Lactobacillus plantarum and lactobacillus acidophilus Than being 1~2:5~7:7~9.
2. a kind of compound probiotic washing lotion for treating yeast infection according to claim 1, it is characterised in that the guarantor Plus the viable bacteria content of Leah lactobacillus, Lactobacillus plantarum and lactobacillus acidophilus is 16~1,900,000,000/milliliter.
3. a kind of compound probiotic washing lotion for treating yeast infection according to claim 1 and 2, it is characterised in that institute The purity for stating mossberry extract is 60~80%.
4. a kind of preparation method of the compound probiotic washing lotion for treating yeast infection, it is characterised in that the preparation method is:
220~250 parts of softened water, 15~25 parts of mossberry extract, 20~25 parts of glucose, food are sequentially added in fermentation tank 1~3 part of salt, 20~25 parts of mixed bacteria liquid;Fermented 24~72 hours at a temperature of 25~35 degree, be then cooled to 18~24 degree, Ferment again 10~12 hours, release bacterium solution, you can packed products.
5. a kind of preparation method of compound probiotic washing lotion for treating yeast infection according to claim 4, its feature It is that the purity of the mossberry extract is 60~80%.
CN201611090541.3A 2016-12-01 2016-12-01 It is a kind of to treat compound probiotic washing lotion of yeast infection and preparation method thereof Pending CN106727870A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1568365A (en) * 2001-10-12 2005-01-19 雷丁大学 Composition comprising a lactobacillus pentosus strain and uses thereof
CN101244091A (en) * 2008-03-14 2008-08-20 中国人民解放军第三军医大学 Application of plants lactobacillus in preparing medicaments for preventing and treating intestinal canal fungus infection
CN103520218A (en) * 2013-10-21 2014-01-22 薛松晓 Composite probiotics for treating yeast infection and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1568365A (en) * 2001-10-12 2005-01-19 雷丁大学 Composition comprising a lactobacillus pentosus strain and uses thereof
CN101244091A (en) * 2008-03-14 2008-08-20 中国人民解放军第三军医大学 Application of plants lactobacillus in preparing medicaments for preventing and treating intestinal canal fungus infection
CN103520218A (en) * 2013-10-21 2014-01-22 薛松晓 Composite probiotics for treating yeast infection and preparation method thereof

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Application publication date: 20170531