CN106492183A - A kind of Chinese medicine compound prescription of preventing and treating livestock and poultry cough and preparation method thereof - Google Patents
A kind of Chinese medicine compound prescription of preventing and treating livestock and poultry cough and preparation method thereof Download PDFInfo
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Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
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Abstract
The present invention relates to a kind of Traditional Chinese medicine compound composition of preventing and treating livestock and poultry cough and preparation method thereof, the Traditional Chinese medicine compound composition is prepared from by the Chinese medicine material medicine of following weight proportion, 150 250 parts of ardisia japonica, 100 200 parts of ginkgo leaf, 100 200 parts of cordate houttuynia, 100 200 parts of coix seed, 50 150 parts of reed rhizome, 50 150 parts of the bark of official magnolia, 20 80 parts of Ligusticum wallichii, 20 80 parts of the Bi roots of grass, 20 80 parts of ginger.Synergy can be produced between its each raw material components, curative effect can be promoted each other, instant effect, without any toxic and side effect, the recurrence after healing can be avoided, and the Chinese medicine compound prescription efficacy stability, not the impact effect because of overlong time.
Description
Technical field
The present invention relates in a kind of field of Chinese medicines for preventing and treating livestock and poultry, more particularly to a kind of preventing and treating livestock and poultry cough
Medicine compound and preparation method thereof.
Background technology
Pig cough illness is a kind of chronic respiratory tract disease for being caused pig by mycoplasma hyopneumoniae, is called pig endemicity lung
Inflammation, is a kind of chronic lung disease of pig, and main clinic symptoms are to cough and pant.The sick initial stage is very brief, dry cough, while flowing out a small amount of
There is asthma phenomenon in serosity nose liquid, stream canescence mucus or purulence nose liquid when seriously ill, mid-term.Body temperature normally, appetite without
Significant change.Sick stage asthma increases, and dehisces to breathe, and lassitude, pig body are become thin, and are reluctant to walk about.
Pig cough illness is most commonly seen with autumn and winter, and different cultivars, the pig at age can infect.Sucking pig is to be easiest to infect
, next to that milking sow, in chronic process or subclinical infection more than Adult Pig.The incidence of disease of pig cough and asthma is higher, expects weight after morbidity
Than increase, poor growth, feed consumption rate also showed increased, feeding cost is caused to increase, economic loss is serious.Therefore, it is badly in need of a kind of
High curative effect, the Chinese medical extract of the preventing and treating piglet cough and asthma of low-residual, can effectively reduce cough and asthma, significantly reduce porcine respiratory disease
The incidence of disease.
Chicken is breathed with cough the extensive generation of disease (the dyspneic disease based on symptom of breathing with cough, be temporarily referred to as disease of breathing with cough), provisions
Chicken production causes larger economic loss.This course of disease is different in size, has several days, Shi Jitian, or even is extended to and delivers for sale, bright
The aobvious economic benefit for reducing colony.Because bacterium, virus, metabolism, raising are not good at causing more than pathogenic factor.The present invention provides a kind of
Traditional Chinese medicine compound composition, its can reduce sucking pig cough and asthma number of times during large scale of pig farm, improve feed intake, strengthen food
It is intended to, can be applicable in large scale of pig farm factory.
Content of the invention
In order to solve the above problems, present invention aim at provide a kind of preventing and treating livestock and poultry cough Traditional Chinese medicine compound composition and
Its preparation method, the medical treatment livestock and poultry cough effect made using the compound are preferable, low cost.
For achieving the above object, the invention discloses a kind of Traditional Chinese medicine compound composition of preventing and treating livestock and poultry cough, the Chinese medicine
Compound is prepared from by the Chinese medicine material medicine of following weight proportion, ardisia japonica 150-250 parts, ginkgo leaf 100-200 parts,
Cordate houttuynia 100-200 parts, coix seed 100-200 parts, reed rhizome 50-150 parts, bark of official magnolia 50-150 part, Ligusticum wallichii 20-80 parts, Bi roots of grass 20-
80 parts, ginger 20-80 parts.
Further, the Traditional Chinese medicine compound composition of described a kind of preventing and treating livestock and poultry cough, the Traditional Chinese medicine compound composition by
The Chinese medicine material medicine of following weight proportion is prepared from, ardisia japonica 180-220 parts, ginkgo leaf 130-170 parts, cordate houttuynia 130-
170 parts, coix seed 130-170 parts, reed rhizome 80-120 parts, bark of official magnolia 80-120 part, Ligusticum wallichii 30-70 parts, Bi roots of grass 30-70 parts, ginger
30-70 parts.
Further, the Traditional Chinese medicine compound composition of described a kind of preventing and treating livestock and poultry cough, the Traditional Chinese medicine compound composition
It is prepared from by the Chinese medicine material medicine of following weight proportion, 200 parts of ardisia japonica, 150 parts of ginkgo leaf, 150 parts of cordate houttuynia, coix seed
150 parts, 100 parts of reed rhizome, 100 parts of the bark of official magnolia, 50 parts of Ligusticum wallichii, 50 parts of the Bi roots of grass, 50 parts of ginger.
Further, the Traditional Chinese medicine compound composition of described preventing and treating livestock and poultry cough, the Traditional Chinese medicine compound composition be powder,
Capsule, oral liquid, granule, pill or tablet.
Present invention also offers a kind of preparation method of the Traditional Chinese medicine compound composition of described preventing and treating livestock and poultry cough, step is such as
Under：
1) bark of official magnolia of recipe quantity, Ligusticum wallichii, 3 taste medicinal material of ginger is weighed, plus 6-12 times is measured water, distills 2-8 hours, extracts volatilization
Oil, the another device of volatile oil are collected, and volatile oil and beta-schardinger dextrin are with 1：10 inclusions, standby；The dregs of a decoction after extraction and ardisia japonica, ginkgo
Leaf, cordate houttuynia, coix seed, reed rhizome, 6 taste medicinal material of the Bi roots of grass add 8-12 times to measure decocting to boil 1-3 time, each 1-3 hours, merge and decoct
Liquid, filtration, stands overnight, leaching supernatant, is evaporated to relative density 1.15-1.27 (50 DEG C), is dried to dry cream.
2) dry cream is ground into fine powder, crosses 100 mesh sieves, dried cream powder is mixed with volatile oil beta cyclodextrin inclusion complex, added suitable
Amount auxiliary material, mixes, prepares capsule, powder, granule or tablet.
Present invention also offers described Traditional Chinese medicine compound composition is used for treating or preventing the medicine that livestock and poultry cough in preparation
In application.
Medicine composition and analysis：
In the Chinese medicine compound prescription of the present invention, ardisia japonica is monarch drug in a prescription, and ginkgo leaf, cordate houttuynia are ministerial drug, coix seed, reed rhizome, the bark of official magnolia,
Ligusticum wallichii, the Bi roots of grass are adjutant, and ginger is to make medicine.
Ardisia japonica：Pungent, slight bitter, puts down.Return lung, Liver Channel.Function with cure mainly：Preventing phlegm from forming and stopping coughing, eliminating dampness and heat are promoting blood circulation and removing blood stasis.With
Cough in new chronic cough, breathe heavily full abundant expectoration, damp and hot yellow subcutaneous ulcer, Amenorrhea stasis blocking, arthralgia due to wind-dampness, traumatic injury.《Bencao Tujing》：" disease diaphragm when controlling
Gas, goes wind phlegm.”《A Supplement to the Compendium of Materia Medica》：" haematemesis internal lesion caused by overexertion is controlled, timid disease is critically ill, coughs into labor long.”《Vegetation is just square》：Rheumatism is controlled " stupid
Numbness, consumptive lung disease are coughed long.Apply cold poison to swell and ache.”《Classification is herbal》：" haematemesis is controlled, cough, gas pain.”
Ginkgo leaf：Sweet, bitter, excessive, put down.The thoughts of returning home, lung channel.Function with cure mainly：Promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain, astringe the lung and relieving asthma, change
Turbid lipid-loweringing.For obstruction of collaterals by blood stasis, chest impediment and cardialgia, hemiplegia, deficiency syndrome of the lung cough and asthma, hyperlipidemia.Ginkgo leaf can promote blood to follow
Ring, prevention of cardiovascular disease.
Cordate houttuynia：Pungent, it is slightly cold.Return lung is passed through.Function with cure mainly：Clearing heat and detoxicating, the carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia.For lung carbuncle
Pyemesis, phlegm heat panting are coughed, hot dysentery, heat gonorrhea, carbuncle sore tumefacting virus.《Compendium of Materia Medica》：The malicious carbuncle swells of radiating, sore hemorrhoid prolapse of the anus, shop disease of breaking solve Nao
Poison.Modern pharmacology experiment shows that this product has the effects such as antibacterial, antiviral, raising immunity of organisms, diuresis.
Coix seed：Sweet, light, cool.Returns spleen, stomach, lung channel.Function with cure mainly：Clearing damp and promoting diuresis, invigorating the spleen to arrest diarrhea, except numbness, apocenosis,
Detoxicating and resolving a mass.For oedema, tinea pedis, difficult urination, splenasthenic diarrhea, arthritis with fixed pain caused by dampness contraction, lung carbuncle, acute appendicitis, wart, cancerous swelling.《Herbal guiding principle
Mesh》：The bright medicine of coix seed sun, energy invigorating the spleen, beneficial stomach.Reinforcing the mother-organ to treat deficiency, therefore consumptive lung disease lung carbuncle uses it.The disease of muscles and bones, with Zhi Yangming be
Sheet, therefore contraction muscular contracture, wandering arthritis person use it.Native energy unboiled water dehumidifying, therefore let out dysentery oedema and use it.
Reed rhizome：Sweet, tremble with fear.Attach to the lung and stomach meridians.Function with cure mainly：Clearing heat-fire, promotes the production of body fluid to quench thirst, relieving restlessness, preventing or arresting vomiting, diuresis.For
Pyreticosis polydipsia, cough with lung heat, lung carbuncle pyemesis, stomach energy is vomitted the sound of vomiting, puckery pain of heat gonorrhea.《Mingyi Bielu》：The main visitor that quenches one's thirst is hot, only little facility.
《Haigoushen》：Big heat, appetizing can be solved.Control the choke sound of vomiting more than.《Tang materia medica》：Treatment is vomitted more good against not lower food, pathogenic heat in the stomach, typhoid patients.
The bark of official magnolia：Bitter, pungent, temperature.Returns spleen, stomach, lung, large intestine channel.Function with cure mainly：Eliminating dampness dissolving phlegm, lower gas removes full.For humidity hysteresis
In wound, gastral cavity ruffian is vomited and diarrhoea, stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm and retained fluid is breathed with cough.Pharmaceutical research shows, the bark of official magnolia have anti-oxidant, antibacterial,
The effect of antiviral, antitumor, anti-inflammatory and antalgic.
Ligusticum wallichii：Taste is pungent, temperature..Return liver, courage, pericardium channel.Function with cure mainly：Blood-activating and qi-promoting, wind-expelling pain-stopping.For the obstruction of qi in the chest heart
Bitterly, chest side of body shouting pain, tumbling and swelling, irregular menstruation, closed dysmenorrhea, lump in the abdomen are suffered from abdominal pain, headache, arthralgia due to wind-dampness.There is significantly calm work
With and analgesic activity.Ligusticum wallichii has inhibitory action to large intestine, deformation, green pus, typhoid bacillus etc..In addition Ligusticum wallichii also has antivitamin E
The effect of deficiency disease.
The Bi roots of grass：Pungent, heat.Return stomach, large intestine channel.Function with cure mainly：Warming spleen and stomach for dispelling cold, lower gas pain relieving.For coldness and pain in the epigastrium, vomit
Tell, have loose bowels, cold obstruction causing qi stagnation, chest impediment and cardialgia, headache, toothache.《Compendium of Materia Medica》：Vim and vigour pain, through uncomfortable, takes with cat-tail pollen pill.《Book on Chinese herbal medicine
Detailed outline》：The hot taste is pungent of gas, sun are floated.Start with Foot yangming Channel.So hot dissipation, the fire of active spleen and lung.Multiplex make us blurred vision, food
Material should not it especially.
Ginger：Pungent, tepor.Return lung, spleen, stomach.Function with cure mainly：Relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, preventing phlegm from forming and stopping coughing solve fish
Crab poison.For anemofrigid cold, gastrofrigid vomiting, cold productive cough are coughed, fish and crab poisoning.Pharmacological research show ginger also have anti-oxidant, change
Kind lipid-metabolism, improve cardio-cerebrovascular function, radiation proof, anti-inflammatory, the effect such as antimicrobial, antitumor, hypoglycemic.
The invention has the advantages that：
The Chinese medicine compound prescription of the present invention have selected the medicine mutually made with mutual reinforcement between, can produce synergy, can increase each other
Enter curative effect, instant effect, without any toxic and side effect, the recurrence after healing can be avoided, and the Chinese medicine compound prescription efficacy stability, not because of overlong time
And impact effect.
Specific embodiment
Following examples are used for the present invention to be described, but are not limited to the scope of the present invention.
Embodiment 1
A kind of Chinese medicine compound prescription of preventing and treating livestock and poultry cough, which is made up of the Chinese medicine material of following weight portion：Ardisia japonica 200g,
Ginkgo leaf 150g, cordate houttuynia 150g, coix seed 150g, reed rhizome 100g, bark of official magnolia 100g, Ligusticum wallichii 50g, Bi roots of grass 50g, ginger 50g.Its
Concrete preparation method is as follows：
1) bark of official magnolia of recipe quantity, Ligusticum wallichii, 3 taste medicinal material of ginger is weighed, plus 6-12 times is measured water, distills 2-8 hours, extracts volatilization
Oil, the another device of volatile oil are collected, and volatile oil and beta-schardinger dextrin are with 1：10 inclusions, standby；The dregs of a decoction after extraction and ardisia japonica, ginkgo
Leaf, cordate houttuynia, coix seed, reed rhizome, 6 taste medicinal material of the Bi roots of grass add 10 times of amount decoctings to boil 3 times, 2 hours every time, merge decoction liquor, filter,
Stand overnight, leaching supernatant, be evaporated to relative density 1.15-1.27 (50 DEG C), be dried to dry cream.
2) dry cream is ground into fine powder, crosses 100 mesh sieves, dried cream powder is mixed with volatile oil beta cyclodextrin inclusion complex, added suitable
Amount auxiliary material, mixes, prepares capsule, powder, granule or tablet.
Embodiment 2
A kind of Chinese medicine compound prescription of preventing and treating livestock and poultry cough, which is made up of the Chinese medicine material of following weight portion：Ardisia japonica 250g,
Ginkgo leaf 120g, cordate houttuynia 120g, coix seed 120g, reed rhizome 80g, bark of official magnolia 80g, Ligusticum wallichii 80g, Bi roots of grass 80g, ginger 70g.Which has
Preparation is as follows：
1) bark of official magnolia of recipe quantity, Ligusticum wallichii, 3 taste medicinal material of ginger is weighed, plus 6-12 times is measured water, distills 2-8 hours, extracts volatilization
Oil, the another device of volatile oil are collected, and volatile oil and beta-schardinger dextrin are with 1：10 inclusions, standby；The dregs of a decoction after extraction and ardisia japonica, ginkgo
Leaf, cordate houttuynia, coix seed, reed rhizome, 6 taste medicinal material of the Bi roots of grass add 10 times of amount decoctings to boil 3 times, 2 hours every time, merge decoction liquor, filter,
Stand overnight, leaching supernatant, be evaporated to relative density 1.15-1.27 (50 DEG C), be dried to dry cream.
2) dry cream is ground into fine powder, crosses 100 mesh sieves, dried cream powder is mixed with volatile oil beta cyclodextrin inclusion complex, added suitable
Amount auxiliary material, mixes, prepares capsule, powder, granule or tablet.
Embodiment 3
A kind of Chinese medicine compound prescription of preventing and treating livestock and poultry cough, including：Ardisia japonica 200g, ginkgo leaf 150g, cordate houttuynia 150g, Job's tears
Benevolence 150g, reed rhizome 100g, bark of official magnolia 100g, Ligusticum wallichii 50g, Bi roots of grass 50g, ginger 50g.Its concrete preparation method is as follows：
The bark of official magnolia of recipe quantity, Ligusticum wallichii, 3 taste medicinal material of ginger is weighed, plus 6-12 times is measured water, distills 2-8 hours, extracts volatilization
Oil, the another device of volatile oil are collected, and volatile oil and Tween-80 are with 1：3 ratios mix, standby；Liquid after extraction, another device storage；Carry
The dregs of a decoction after taking add 10 times of amount decoctings to boil 3 times with ardisia japonica, ginkgo leaf, cordate houttuynia, coix seed, reed rhizome, 6 taste medicinal material of the Bi roots of grass, per
Secondary 2 hours, merge decoction liquor, filtration is stood overnight, leaching supernatant, merged with above-mentioned liquid, be evaporated to relative density
The clear cream of 1.05-1.15 (50 DEG C), plus ethanol makes alcohol content to 60%～70%, stands 24～48 hours, filters, filtrate is reclaimed
Ethanol is extremely without alcohol taste, plus the preservative of 1-3 ‰, is well mixed with the mixture of volatile oil Tween-80, adds water to 1000ml, makes
Into oral liquid.
Embodiment 4
A kind of Chinese medicine compound prescription of preventing and treating livestock and poultry cough, which is made up of the Chinese medicine material of following weight portion：Ardisia japonica 200g,
Ginkgo leaf 150g, cordate houttuynia 150g, coix seed 150g, reed rhizome 100g, bark of official magnolia 100g, Ligusticum wallichii 50g, Bi roots of grass 50g, ginger 50g
The flavour of a drug of above-mentioned recipe quantity are weighed, be dry, pulverize, crossed 100 mesh sieves, make powder.
Test example 1
The therapeutic effect coughed by pig
Clinical trial animal selects Beijing pig farm 100-120 ages in days, body weight in the DLY three way cross of 40kg-50kg
Pig 240, clinical symptoms occur breathing, cough, generate heat, losing the appetite or without appetite for pig.The isolation of ill pig is individually raised,
Feeding complete feed, and 6 groups are randomly divided into, 40 per group, 6 groups of feeding environments are identical, and experimental period is carried out 7 days altogether；Empty
White control group is left intact, and drug control group is used according to an instruction treatment with institute's control drug " datura flower asthma relieving powder "；Real
1 group is tested for 1 group of embodiment, 2 groups of experiment lacks monarch drug in a prescription group for embodiment 1, and 3 groups of experiment lacks ministerial drug group for embodiment 1, and 4 groups of experiment is
2 groups of embodiment, day dose be：The compound spice 1kg feedings of the present invention per 100g, 2 times a day.Pass through gastrointestinal absorption after oral
Reach the purpose for the treatment of disease.
Efficacy assessment standard：
Recovery from illness：Through treatment, clinical symptoms are wholly absent, and spirit, appetite recover normal
Effectively：Through treatment, clinical symptom remission, spirit, appetite gradually recover.
Invalid：Through treatment, without alleviation, spirit, appetite are without improvement or even dead for clinical symptoms.
1 present invention of table treats the situation contrast of pig cough with other medicines
| Group | Number of cases | Recovery from illness | Effectively | Invalid | Efficient % |
| Blank control group | 40 | 0 | 4 | 36 | 10 |
| Datura flower asthma relieving powder group | 40 | 35 | 2 | 3 | 92.5 |
| Test 1 group | 40 | 36 | 2 | 2 | 95 |
| Test 2 groups | 40 | 2 | 6 | 32 | 20 |
| Test 3 groups | 40 | 25 | 8 | 7 | 82.5 |
| Test 4 groups | 40 | 33 | 3 | 4 | 90 |
Conclusion：The efficient of blank control group is 10%, the efficient of datura flower asthma relieving group is 92.5%, and testing 1 group has
Efficiency is 95%, and the efficient of 2 groups of experiment is 20%, and the efficient of 3 groups of experiment is 82.5%, and the efficient of 4 groups of experiment is
90%.Result of the test shows that the Chinese medicine compound prescription reasonable recipe in the present invention, for treating the cough effect is significant of pig.
Test example 2
The therapeutic effect coughed by chicken
21 age in days chicken 600 of the clinical trial animal from Beijing chicken house, clinical symptoms are decreased obviously for feed intake, essence
Refreshing depressed, unilateral or bilateral nasal sinus, eyelid swelled, cough, sneeze, constantly getting rid of head, have difficulty in breathing.By the isolation of ill chicken individually
Raise, feed complete feed, and be randomly divided into 6 groups, 100 per group, 6 groups of feeding environments are identical, and experimental period carries out 7 altogether
My god；Blank control group is left intact, and drug control group is made by its specification with institute's control drug " Maxingshigan oral liquid "
With treatment；1 group is tested for 1 group of embodiment, 2 groups of experiment lacks monarch drug in a prescription group for embodiment 1, and 3 groups of experiment lacks ministerial drug group for embodiment 1,
4 groups are tested for 2 groups of embodiment, day dose be：Per 100g, compound spice 1kg feedings of the present invention, daily 1-2 time；Logical after oral
Cross the purpose that gastrointestinal absorption reaches treatment disease.
Efficacy assessment standard：
Cure：Spirit, appetite, breathing recover normal, and tracheae does not have mucus, moistening, and lungs, Pathological cut open inspection are without notable
Histopathologic change, is judged to fully recover, and it is cure rate that chicken number of fully recovering accounts for the percentage of this group of chicken number.
At the end of have symptom：Clinical symptoms do not improve or even increase.
2 present invention of table treats the situation contrast of chicken cough with other medicines
| Group | Death rate % | Cure rate % | At the end of have symptom rate % |
| Blank control group | 30 | 0 | 70 |
| Drug control group | 10 | 86 | 4 |
| Test 1 group | 6 | 92 | 2 |
| Test 2 groups | 25 | 8 | 67 |
| Test 3 groups | 12 | 79 | 9 |
| Test 4 groups | 8 | 88 | 4 |
Conclusion：The cure rate of blank control group is 0, and the cure rate of datura flower asthma relieving group is 86%, and the cure rate for testing 1 group is
92%, the cure rate for testing 2 groups is 8%, and the cure rate for testing 3 groups is 79%, and the cure rate for testing 4 groups is 88%.Test knot
Fruit shows that the Chinese medicine compound prescription reasonable recipe in the present invention, for treating the cough illness effect is significant of chicken, with numb apricot stone glucoside oral liquid
Group compares indifference in terms of cure rate.
Test example 3
The prevention coughed by chicken
Clinical trial animal is randomly divided into 5 groups from the 21 age in days chicken 1000 of Beijing chicken house, per group 200,5 groups
Feeding environment is identical, and complete feed is fed in isolation, and experimental period is carried out 7 days altogether；Blank control group is left intact, real
1 group is tested for 1 group of embodiment, 2 groups of experiment lacks monarch drug in a prescription group for embodiment 1, and 3 groups of experiment lacks ministerial drug group for embodiment 1, and 4 groups of experiment is
2 groups of embodiment, day dose be：Per 10g, compound spice 1kg feedings of the present invention, daily 1-2 time；Inhaled by intestines and stomach after oral
Receive the purpose for reaching treatment disease.
The preventive effect that 3 Chinese medicine compound prescription of the present invention of table is coughed to chicken
| Group | Total (only) | Morbidity number (only) | Do not fall ill number (only) | Effective prevention rate (%) |
| Blank control group | 200 | 78 | 122 | 61 |
| Test 1 group | 200 | 15 | 185 | 92.5 |
| Test 2 groups | 200 | 65 | 135 | 67.5 |
| Test 3 groups | 200 | 26 | 174 | 87 |
| Test 4 groups | 200 | 19 | 181 | 90.5 |
Conclusion：Effective prevention rate of blank control group is 61%, and the effective prevention rate for testing 1 group is 92.5%, tests 2 groups
Effective prevention rate be 67.5%, test 3 groups effective prevention rate be 87%, test 4 groups effective prevention rate be 90.5%, examination
Test result to show, the Chinese medicine composition reasonable recipe in the present invention has preferable preventive effect to the cough of chicken.
The present invention is found surprisingly that the collocation of each component of the present invention has synergistic function.
Although, the present invention is described in detail above to have used general explanation and specific embodiment, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (6)
1. the Traditional Chinese medicine compound composition that a kind of preventing and treating livestock and poultry cough, it is characterised in that：The Traditional Chinese medicine compound composition is by following heavy
The Chinese medicine material medicine of amount proportioning is prepared from, ardisia japonica 150-250 parts, ginkgo leaf 100-200 parts, cordate houttuynia 100-200 parts, the heart of a lotus seed
Seed of jog's tears 100-200 parts, reed rhizome 50-150 parts, bark of official magnolia 50-150 part, Ligusticum wallichii 20-80 parts, Bi roots of grass 20-80 parts, ginger 20-80 parts.
2. Traditional Chinese medicine compound composition as claimed in claim 1, it is characterised in that：The Traditional Chinese medicine compound composition is by following weight
The Chinese medicine material medicine of proportioning is prepared from, ardisia japonica 180-220 parts, ginkgo leaf 130-170 parts, cordate houttuynia 130-170 parts, Job's tears
Benevolence 130-170 part, reed rhizome 80-120 parts, bark of official magnolia 80-120 part, Ligusticum wallichii 30-70 parts, Bi roots of grass 30-70 parts, ginger 30-70 parts.
3. Traditional Chinese medicine compound composition as claimed in claim 1, it is characterised in that：The Traditional Chinese medicine compound composition is by following weight
The Chinese medicine material medicine of proportioning is prepared from, 200 parts of ardisia japonica, 150 parts of ginkgo leaf, 150 parts of cordate houttuynia, 150 parts of coix seed, reed rhizome
100 parts, 100 parts of the bark of official magnolia, 50 parts of Ligusticum wallichii, 50 parts of the Bi roots of grass, 50 parts of ginger.
4. Traditional Chinese medicine compound composition according to claim 1, it is characterised in that：The composition is any pharmaceutically useful dose
Type.
5. Traditional Chinese medicine compound composition according to claim 4, it is characterised in that：The formulation is selected from：Tablet, capsule,
Granule, pill, powder, paste, sublimed preparation, pulvis, solution, injection, suppository, spray, drops, patch.
6. the preparation method of the Traditional Chinese medicine compound composition described in claim 1, it is characterised in that：The step of preparation method, is such as
Under：The bark of official magnolia, Ligusticum wallichii, 3 taste medicinal material of ginger is taken, plus 6-12 times is measured water, distills 2-8 hours, extract volatile oil, the another device of volatile oil is received
Collection, volatile oil and beta-schardinger dextrin are with 1：10 inclusions, standby；The dregs of a decoction after extraction and ardisia japonica, ginkgo leaf, cordate houttuynia, coix seed,
Reed rhizome, 6 taste medicinal material of the Bi roots of grass add 8-12 times to measure decocting to boil 1-3 time, each 1-3 hours, merge decoction liquor, and filtration stands overnight, filters
Supernatant is taken, relative density 1.15-1.27 (50 DEG C) is evaporated to, is dried to dry cream, dry cream is ground into fine powder, cross 100
Mesh sieve, dried cream powder are mixed with volatile oil beta cyclodextrin inclusion complex, add appropriate amount of auxiliary materials, are mixed, are prepared capsule, powder, particle
Agent or tablet.
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