CN106491971A - A kind of for treating Chinese medicine composition of pulpitiss and preparation method thereof - Google Patents
A kind of for treating Chinese medicine composition of pulpitiss and preparation method thereof Download PDFInfo
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- CN106491971A CN106491971A CN201710002659.4A CN201710002659A CN106491971A CN 106491971 A CN106491971 A CN 106491971A CN 201710002659 A CN201710002659 A CN 201710002659A CN 106491971 A CN106491971 A CN 106491971A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract
The invention discloses a kind of Chinese medicine composition for treating pulpitiss, including Flos Chrysanthemi, Maca, Rhizoma Polygonati, Radix Campylotropis Hirtella (Herba Myrsines Africanae), Herb Gynostemmae Pentaphylli, Folium Mori, Radix Puerariae, Semen Cassiae, the Radix Polygoni Multiflori, Fructus Ligustri Lucidi, Radix Astragali, Radix Notoginseng piece, Rhizoma Chuanxiong, Caulis Spatholobi, Fructus Rosae Laevigatae, Herba Taxilli, Radix Codonopsis, Fructus Corni, Herba Ipomoeae Cairicae, Fructus Lycii, Morinda offcinalis How, the Cortex Eucommiae, the Radix Paeoniae Alba, Semen Cuscutae, Fructus Jujubae, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae, Cornu Cervi Pantotrichum and deer tail.The Chinese medicine composition prescription of the present invention is rationally, instant effect, the course for the treatment of is shorter, medication is convenient, have no side effect, can be with effective control and elimination pulpitiss disease；Not only there is good therapeutic effect to acute pulpitiss, also have obvious therapeutical effect to chronic pulpitiss, periodontitis, gingivitiss；Cooperate between Chinese medicine composition each component, synergism, not only increase the respective treatment characteristic of medicine, and by dredge the meridian passage and adjust immunologic function, improve the body constitution of patient, strengthen autoimmunity, preferably reach healing rehabilitation efficacy.
Description
Technical field
The present invention relates to technical field of Chinese medicines.More particularly, to a kind of Chinese medicine composition for treating pulpitiss and
Its preparation method.
Background technology
Dental pulp is mainly comprising neurovascular loose connective tissue, positioned at the dental pulp intracavity of Its pulp.Pulpitiss are
Refer to that antibacterial or toxin invade the inflammation for being located at that the dental pulp of tooth center causes, have bacterium factors, physics the reason for cause pulpitiss
Factor, chemical factor and idiopathic factor, its topmost cause of disease is exactly to infect, and antibacterial is the important paathogenic factor of dental pulp disease,
Once dental pulp is inflamed, inflammatory exudate is difficult drain, and pulp cavity is intrinsic pressure to be increased quickly, and generation has an intense pain.
Pulpitiss are divided into by acute pulpitiss and two class of chronic pulpitiss with the pathological change of dental pulp often clinically.Acute tooth
Marrow inflammation can be developed by pulp hyperemia, also can be by chronic pulpitiss acute attack.Chronic pulpitiss are clinically most common,
Atypical symptom, some cases can be without spontaneous pain.If acutely inflamed exudate obtains drain, but inflammation fails thoroughly to disappear
When removing, chronic inflammatory disease is can also convert into.If conversely, Abwehrkraft des Koepers lower, or local drainage is not smooth, chronic pulpitiss can turn again
Turn to acute pulpitiss, i.e. chronic pulpitiss acute attack.
How to be treated using surgical operation at present, not only expensive, and also therapeutic process is very painful, and patient is difficult
Stand.From for traditional Chinese medical science angle, the pathogenesis of various pulpitiss disease mainly has wind-fire to violate tooth, wind and cold criminal's tooth, stomach-fire criminal's tooth, asthenic fire
Violate the reasons such as tooth and cause.And Chinese medicine is because having low price, curative effect substantially and the advantage such as have no side effect, by increasing patient
Received, but the medicine of the treatment pulpitiss for occurring in the market, rear slowly effect is taken, is easily recurred, is not reached healing
Effect.
Therefore, the invention provides a kind of Chinese medicine composition for treating pulpitiss, its prescription rationally, instant effect, treatment
Journey is shorter, medication is convenient, have no side effect, and with effective control and can eliminate pulpitiss disease.
Content of the invention
It is an object of the present invention to provide a kind of Chinese medicine composition for treating pulpitiss.In proposed by the present invention
Drug composition can conveniently and efficiently be alleviated, release pulpitiss patient suffering, and can effective control and elimination pulpitiss disease.
Further object is that providing a kind of preparation method for treating the Chinese medicine composition of pulpitiss.
For reaching above-mentioned purpose, the present invention adopts following technical proposals：
A kind of Chinese medicine composition for treating pulpitiss, including the crude drug of following parts by weight：15～30 parts of Flos Chrysanthemi,
8～12 parts of Maca, 12～14 parts of Rhizoma Polygonati, 2～4 parts of Radix Campylotropis Hirtella (Herba Myrsines Africanae), 15～20 parts of Herb Gynostemmae Pentaphylli, 12～24 parts of Folium Mori, Radix Puerariae 20～25
Part, 30～45 parts of Semen Cassiae, 10～25 parts of the Radix Polygoni Multiflori, 8～12 parts of Fructus Ligustri Lucidi, 10～25 parts of Radix Astragali, 6～10 parts of Radix Notoginseng piece, Rhizoma Chuanxiong 2
～5 parts, 8～12 parts of Caulis Spatholobi, 8～12 parts of Fructus Rosae Laevigatae, 10～15 parts of Herba Taxilli, 2～5 parts of Radix Codonopsis, 10～15 parts of Fructus Corni, five
10～15 parts of pawl dragon, 8～12 parts of Fructus Lycii, 8～12 parts of Morinda offcinalis How, 8～12 parts of the Cortex Eucommiae, 8～12 parts of the Radix Paeoniae Alba, Semen Cuscutae 20～25
Part, 8～12 parts of Fructus Jujubae, 8～12 parts of Radix Rehmanniae Preparata, 8～12 parts of the Rhizoma Atractylodis Macrocephalae, 8～12 parts of the Radix Rehmanniae, 2～5 parts of Cornu Cervi Pantotrichum, 2～5 parts of deer tail.
Preferably, the Chinese medicine composition includes the crude drug of following parts by weight：15～30 parts of Flos Chrysanthemi, Maca 8～12
Part, 12～14 parts of Rhizoma Polygonati, 15～20 parts of Herb Gynostemmae Pentaphylli, 12～24 parts of Folium Mori, 20～25 parts of Radix Puerariae, 30～45 parts of Semen Cassiae, the Radix Polygoni Multiflori
10～25 parts, 20～25 parts of Semen Cuscutae, 8～12 parts of Morinda offcinalis How, 8～12 parts of the Cortex Eucommiae.
Preferably, the Chinese medicine composition includes the crude drug of following parts by weight：15 parts of Flos Chrysanthemi, 8 parts of Maca, Rhizoma Polygonati 12
Part, 15 parts of Herb Gynostemmae Pentaphylli, 12 parts of Folium Mori, 20 parts of Radix Puerariae, 30 parts of Semen Cassiae, 10 parts of the Radix Polygoni Multiflori, 20 parts of Semen Cuscutae, 8 parts of Morinda offcinalis How, the Cortex Eucommiae 8
Part.
Preferably, the Chinese medicine composition can be made into pill, sublimed preparation, powder, tablet, unguentum or decoction.
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", all medicine compatibilities, the monarch and his subjects pull together, help make auxiliary altogether, with benefit
Gas spleen invigorating, nourishing the liver to improve visual acuity, clearing away lung-heat and moistening for dryness, QI and blood regulating, dispelling wind dredging collateral, strengthening vital QI to eliminate pathogenic factors, regulation immunologic function, promotion warming the meridian dissipate
Cold, effect of blood circulation promoting and blood stasis dispelling, relieving spasm to stop pain.Good synergism is produced between each component, not only increases antiinflammatory, anti-tissue
Amine and the effect of suppression anaerobe, also so that the inflammation of pulp tissue is able to control rapidly and eliminate, and can promote pulp tissue
Quick recovery and early recovery normal physiological function, it is adaptable to the treatment of pulpitiss, have no toxic side effect, and various Chinese medicine preparation are taken
Convenient.
Compatibility of drugs of the present invention is proper, reasonable recipe, and effect of its each herbal medicine is：
Flos Chrysanthemi：Glycoside containing chrysanthemum, aminoacid, flavonoid and multivitamin and trace element, in chrysanthemum containing adenine, choline,
Stachydrine etc., the volatile oil extracting from chrysanthemum, containing Chrysanthemum ketone, Borneolum Syntheticum, borneol acetate etc., with dispelling wind, heat clearing away, bright
The effect of mesh, removing toxic substances.Flos Chrysanthemi has antibacterial, antiviral, antiinflammatory, anti-ageing multiple pharmacologically actives of waiting for a long time.
Maca：Also known as Mai Ka or Lepidinm meyenii Walp, with muscle power, stamina intensifying and resisting fatigue is increased, enhance metabolism,
Renitency simultaneously lifts the sexuality of the mankind and animal, the effects such as fertility and galactopoiesiss.Its chemical composition composition：Protein
Content is more than 10%, 59% carbohydrate；8.5% fiber, include abundant zinc, calcium, ferrum, titanium, rubidium, potassium, sodium,
The mineral such as copper, manganese, magnesium, strontium, phosphorus, iodine, and contain vitamin C, B1, B2, B6, A, E, B12, B5, fat content not high but its
In mostly be unsaturated fatty acid, up to more than 53%, natural activity composition includes alkaloid, Semen Sinapiss to the content of linoleic acid plus linolenic acid
Oily glycosides and its catabolite benzyl isothiocyanate, sterol, polyphenols etc..
Rhizoma Polygonati：Also known as Rhizoma Polygonati Cirrhifolii, Caput Gallus domesticuss ginseng.Containing much starch, sugar, fat, protein, carotene, vitamin and
Other nutritional labelings multiple, with functions such as boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.
Radix Campylotropis Hirtella (Herba Myrsines Africanae)：Profile bar rope tight knot, the green and brown fresh profit of color and luster.Remove and there is with general Folium Camelliae sinensis benefit of refreshing oneself to think, allaying tiredness, life
Tianjin diuresis, antipyretic sunstroke prevention, bactericidal antiphlogistic, removing toxic substances diseases prevention, promoting digestion greasy, outside the health care such as defatting beauty, also have anti-cancer,
Blood fat reducing, anti-ageing special efficacy of waiting for a long time.
Herb Gynostemmae Pentaphylli：Draft a document matter Climbing Plant, main active ingredient is gypenoside, Herb Gynostemmae Pentaphylli glucoside (polysaccharide), water-soluble
Acidic amino acid, flavonoid, multivitamin, trace element, mineral etc., with eliminating inflammation and expelling toxin, eliminating phlegm and stopping cough, strengthening vital QI to eliminate pathogenic factors etc.
Effect, cures mainly weak body void, nephrasthenia emission, leukopenia, hyperlipemia, viral hepatitis, chronic gastroenteritiss, chronic gas
Guan Yan etc..
Folium Mori：It is the dried leaves of moraceae plants mulberry, cold in nature, sweet in the mouth, hardship have dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving
Effect, can treat anemopyretic cold, lung-heat type cough, dizziness headache, the dim-sighted disease of conjunctival congestion.
Radix Puerariae：Dry root for legume pueraria lobata.Liver cell regeneration ability is improved, promotes once metabolism, plus
Strong liver detoxification ability, expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, the work(of Shengyang Zhixie, coronary atherosclerosis are had blood circulation it
Effect.It is usually used in fever caused by exogenous pathogens headache, stiffness of the nape pain, thirsty, to quench one's thirst, measles without adequate eruption, hematodiarrhoea are had loose bowels；Hypertension neck pain.
Semen Cassiae：It is the dry mature seed of leguminous plant Semen Cassiae or little Cassia tora, Semen Cassiae bitter in the mouth, sweet, salty, cold nature,
Enter liver, kidney, large intestine channel；Loosening bowel to relieve constipation, lipid-loweringing improving eyesight, treatment constipation and hyperlipidemia, hypertension.Liver heat removing and eyesight improving, diuretic relieving constipation, has
Laxative action, reducing blood pressure and blood fat.
The Radix Polygoni Multiflori：Dried root of this product for polygonum multiflorum thunb, indication nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispels
Wind, removing toxic substances.Main blood deficiency Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine are just
Secret, chronic malaria body void, rubella itch, carbuncle sore, scrofula, hemorrhoid.
Fructus Ligustri Lucidi：For the mature fruit of Oleaceae plants Fructus Ligustri Lucidi, the effects such as with liver and kidney tonifying, improving eyesight, clearind deficient heat, cure mainly
Have a dizzy spell, early whitening of beard and hair, blurring of vision, fever due to yin deficiency etc..
Radix Astragali：For leguminous plant Radix Astagali or the root of Radix Astragali, with granulation promoting inducing diuresis to remove edema, invigorating QI to consolidate the body surface resistance, arresting sweating
Gu the effects such as de-, torr sore myogenic.
Radix Notoginseng piece：Radix Notoginseng is araliaceae ginseng plant, and perennial herb, with hemostasis by removing blood stasis, reducing swelling and alleviating pain, reduction gallbladder
The effects such as sterin, reduction triglyceride.
Rhizoma Chuanxiong：Efficacy effect acrid in the mouth, warm in nature, with promoting flow of QI and blood, wind-expelling pain-stopping, for treating menoxenia, amenorrhea
The diseases such as dysmenorrhea, abdominal mass stomachache, costa sternaless twinge, treating swelling and pain by traumatic injury, headache, rheumatic arthralgia
Caulis Spatholobi：There is relaxing muscles and tendons to promote blood circulation, effect of nourishing blood for regulating menstruation；Cure mainly rheumatic arthralgia, numb hand and foot, quadriplegia, the moon
Through uncomfortable, blockage of menstruation, dysmenorrhea, amenorrhea, leukopenia.
Fructus Rosae Laevigatae：The effect of there is astringent sperm contracting urine, stopping metrorrhagia and leukorrhagia, relieving diarrhea with astringents.It is usually used in emission and spermatorrhea, enuresis frequent micturition,
Bleeding not during menses, protracted dysentery and diarrhea.
Herba Taxilli：Indication invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, beneficial blood are antiabortive.
Radix Codonopsis：There is invigorating the spleen and replenishing QI, effect of strengthening spleen and tonifying lung.There are enhancing immunity, expansion of blood vessels, blood pressure lowering, improve and micro- follow
The effects such as ring, enhancing hemopoietic function.In addition there is castering action to the leukopenia that chemotherapy radiotherapy causes.
Fructus Corni：Have invigorating the liver and kidney, arresting seminal emission gas, admittedly collapse effect.Soreness of waist and knee joint is cured mainly, dizziness, tinnitus, sexual impotence are lost
Essence, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart shake scattered pulse.
Herba Ipomoeae Cairicae：There is heat clearing away, diuretic, removing toxic substances, the effect for silt rheumatism of dispelling.Cure mainly laryngopharynx swelling and pain, furuncle and phyma carbuncle, furuncle,
Dysentery hematuria, blood are turbid, traumatic injury, venom etc..
Fructus Lycii：Medicinal function is cured mainly：Caused by liver and kidney deficiency；Have a dizzy spell；Visually unclear；Soreness of the waist and knees；Impotence and seminal emission；Asthenia
Cough；Quench one's thirst taking fluids profusely.
Morinda offcinalis How：Contain glycoside, monosaccharide, several amino acids and a large amount of potassium magnesium.Function kidney-replenishing, strengthening bone and muscle, enhance immunity.Main
Control kidney deficiency, soreness of the waist and knees cold womb, menoxenia, few abdomen crymodynia, rheumatic arthralgia etc..
The Cortex Eucommiae：There is liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through pacifying amine, enhancing immunity.Have clear
Except internal rubbish, strengthen human body cell metabolism, prevent muscle skeleton aging, balanced human's blood pressure, decomposer inner cholesterol,
Reduce body fat, recover blood vessel elasticity, diuresis heat-clearing, broad-spectrum antiseptic, stimulating central nervous system improve white blood cell pharmacological action.
The Radix Paeoniae Alba：Nourishing blood for regulating menstruation, smooth liver and relieve pain, astringing YIN to stop sweating, this product have Pinggan Yang, nourishing liver-YIN, adjust irritability, relieving spasm to stop pain
Effect.
Semen Cuscutae：There is nourishing the liver and kidney, benefit essence bone, invigorating QI to consolidate the body surface resistance diuretic and maintain drug, nourishing the liver to improve visual acuity, expelling pus and promoting granulation, antidiarrheal
The effect of.
Fructus Jujubae：Fructus Jujubae sweet in the mouth is warm in nature, taste warp, has invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind to relax the function of the property of medicine.
Radix Rehmanniae Preparata：There is YIN nourishing effect of enriching blood, can be used for the diseases such as blood deficiency and yellow complexion, dizziness, palpitation and insomnia, menoxenia, metrorrhagia,
The disease such as also can be used for the hectic fever hectic fever due to YIN-deficiency of deficiency of kidney yin, night sweat, pass out semen, quench one's thirst.
The Rhizoma Atractylodis Macrocephalae：There is invigorating the spleen and benefiting QI, eliminate dampness and have diuretic effect, hidroschesis are antiabortive, hepatic cholagogic, anticoagulant, anti-gastric-ulcer, antioxidation,
Antibacterial, effect of enhance immunity, for spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, edema, spontaneous perspiration, frequent fetal movement.
The Radix Rehmanniae：The effect of there is clearing away heat and cooling blood, joins the army blood for curing mainly warm febrile disease, and high fever coma, dry tongue are deep red；Control epidemic febrile disease
In the later stage, waste heat not to the greatest extent, hinder, night fever abating at dawn, red tongue rapid pulse person by cloudy liquid；Warm febrile disease is joined the army blood, blood-heat and toxin exuberance, hematemesis and epistaxiss,
Atropurpureus macula；YIN nourishing and the production of body fluid promoting, injury thirst, Heat Diabetes control the diseases such as epidemic febrile disease impairment of YIN, dry constipation of intestines.
Cornu Cervi Pantotrichum：Containing phospholipid, glycolipid, glue fat, hormone, fatty acid, aminoacid, protein and calcium, phosphorus, magnesium, sodium in Cornu Cervi Pantotrichum
Deng composition, wherein aminoacid ingredient accounts for more than half of total composition.The cellular immunization and humoral immune function of body can be improved,
Promote the conversion of lymphocyte, the effect with immunopotentiating agent.It can increase body defence capability to external world, adjust in vivo
Immunologic balance, so as to avoid disease occur and promote wound healing, sick body rehabilitation, so as to play strengthening body, opposing aging
Effect.Have kidney-Yang invigorating, fill blood, beneficial marrow, bone and muscle strengthening the effects such as.
Deer tail：Contain abundant protein, colloid calcium lactophosphate, vitamin C, vitamin D, vitamin e, Vitamin B12, magnesium
And the mineral such as zinc.Strengthening waist and nourishing kidney, big tonifying deficiency, physical strength reinforcing, allaying tiredness, energy blood circulation promoting, to treating rheumatism
There is significant curative effect, be the strong health product of good general.
The Chinese medicine each component that the present invention is selected meets the regulation of the Drug Administration Law of People's Republic of China, using each taste Chinese medicine
Comprehensive function treat and prevent pulpitiss, nontoxic to human body.Acute toxicity test and storage through white mice and rat
Product property toxicity test shows that underproof animal has no any toxic reaction, through anatomic observation hemogram, liver function, each organs and tissues
Morphology finding compares zero difference with matched group, it was demonstrated that its safety of medicine reliability.
For reaching above-mentioned second purpose, the present invention adopts following technical proposals：
A kind of preparation method for treating the Chinese medicine composition of pulpitiss, the Chinese medicine composition make pill, including
Following steps：
1) weigh above-mentioned each component according to formula proportion, carry out processing, dry, pulverize after sieve；
2) after sieve above-mentioned processing, medicated powder is sufficiently mixed using ripening sterilization treatment, and first temperature is brought rapidly up to 110
DEG C, 100 DEG C are subsequently slowly dropped to, obtain preparing required pill medicated powder；
3) take high-purity Mel to be put in above-mentioned medicated powder input pot in pot when being brewed into moderate, stirred, stirring is
Cool down after even, pill block, rub ball bar, pill grain with the hands.
Preferably, the Chinese medicine composition makes sublimed preparation, comprises the steps：
1) weigh above-mentioned each component by formula proportion, carry out processing, dry, pulverize after sieve；Medicated powder after sieve is fully mixed
Close, be lyophilized into powder, be then ground to fine powder；
2) a small amount of fine powder is placed in coating pan and is rolled, Auxiliary Liquid Material on a small quantity based on water is sprayed into when rolling, formed
Tiny damp granules, add a small amount of mixed powder, roll, then jetting liquid adjuvant, repeatable operation, make sublimed preparation basic
Grain after, through screening, select spherical pellet mould of uniform size, to ball mould continue jetting liquid adjuvant, upper powder, round as a ball, screening, until
Make the little pill that particle diameter is 1.5～2mm；
3) little pill is placed in drying in oven, is then placed in coating pan, add cured powder on a small quantity, tumbling is until little
Till pellet surface light.
Preferably, the Chinese medicine composition makes powder, comprises the steps：Above-mentioned each component is weighed by formula proportion,
Carry out processing, dry, pulverize after sieve；Medicated powder after sieve is sufficiently mixed, powder is lyophilized into, fine powder is then ground to, is mixed thoroughly.
Preferably, the Chinese medicine composition makes tablet, comprises the steps：
1) weigh above-mentioned each component by formula proportion, carry out processing, dry, pulverize after sieve；Medicated powder after sieve is fully mixed
Close, add after mixing and enter granulation in granulator；
2) gained granule is placed in airpillow-dry agent and is dried process；
3) dried granule is put into pelletizing machine granulate, to granulate after hybrid particles carry out sheeting operation.
Preferably, the Chinese medicine composition makes unguentum, comprises the steps：
1) weigh above-mentioned each component by formula proportion, carry out processing, dry, pulverize after sieve；Medicated powder after sieve is fully mixed
Close, do after spray vinegar on the mixture and fry, the medicine of fried dry is exposed to the sun after 12h, fine powder is ground into and is sieved；
2) in the mixed-powder for sieving according to weight 1:4 ratio adds Oleum sesami and Colophonium to be tuned into pasty ointment.
Preferably, the Chinese medicine composition makes decoction, comprises the steps：Above-mentioned each component is weighed by formula proportion,
The water of 5-10 times of raw material components total amount is added, and with 10-20 minutes being cooked by slow fire after being boiled by fire, filter and remove residue is obtained final product.
Beneficial effects of the present invention are as follows：
(1) present invention treats and prevents pulpitiss disease, its medicine nontoxic to human body using the comprehensive function of each taste Chinese medicine
Thing is safe and reliable.
(2) Chinese medicine composition prescription of the present invention is rationally, instant effect, the course for the treatment of is shorter, medication is convenient, have no side effect, can
With effective control and elimination pulpitiss disease.
(3) present invention not only has good therapeutic effect to acute pulpitiss, to chronic pulpitiss, periodontitis, gingivitiss
Also there is obvious therapeutical effect.
(4) cooperate between Chinese medicine composition each component proposed by the present invention, synergism, not only increase medicine each
From treatment characteristic, and by dredge the meridian passage and adjust immunologic function, improve the body constitution of patient, strengthen autoimmune
Power, preferably reaches healing rehabilitation efficacy.
Specific embodiment
In order to be illustrated more clearly that the present invention, with reference to preferred embodiment, the present invention is described further.Ability
Field technique personnel should be appreciated that following specifically described content is illustrative and be not restrictive, and should not limit this with this
The protection domain of invention.
Embodiment 1
A kind of Chinese medicine composition for treating pulpitiss, including the crude drug of following parts by weight：
15 parts of Flos Chrysanthemi, 8 parts of Maca, 12 parts of Rhizoma Polygonati, 2 parts of Radix Campylotropis Hirtella (Herba Myrsines Africanae), 15 parts of Herb Gynostemmae Pentaphylli, 12 parts of Folium Mori, 20 parts of Radix Puerariae, Semen Cassiae
30 parts of son, 10 parts of the Radix Polygoni Multiflori, 8 parts of Fructus Ligustri Lucidi, 10 parts of Radix Astragali, 6 parts of Radix Notoginseng piece, 2 parts of Rhizoma Chuanxiong, 8 parts of Caulis Spatholobi, 8 parts of Fructus Rosae Laevigatae, Herba Taxilli
Raw 10 parts, 2 parts of Radix Codonopsis, 10 parts of Fructus Corni, 10 parts of Herba Ipomoeae Cairicae, 8 parts of Fructus Lycii, 8 parts of Morinda offcinalis How, 8 parts of the Cortex Eucommiae, 8 parts of the Radix Paeoniae Alba, Semen Cuscutae
20 parts, 8 parts of Fructus Jujubae, 8 parts of Radix Rehmanniae Preparata, 8 parts of the Rhizoma Atractylodis Macrocephalae, 8 parts of the Radix Rehmanniae, 2 parts of Cornu Cervi Pantotrichum, 2 parts of deer tail.
The Chinese medicine composition makes decoction, weighs above-mentioned each component by formula proportion, adds 5-10 times of raw material components total
The water of amount, with 10-20 minutes are cooked by slow fire after being boiled by fire, filter and remove residue obtains final product decoction.
Embodiment 2
A kind of Chinese medicine composition for treating pulpitiss, including the crude drug of following parts by weight：
30 parts of Flos Chrysanthemi, 12 parts of Maca, 14 parts of Rhizoma Polygonati, 4 parts of Radix Campylotropis Hirtella (Herba Myrsines Africanae), 20 parts of Herb Gynostemmae Pentaphylli, 24 parts of Folium Mori, 25 parts of Radix Puerariae, certainly
45 parts of pine torch, 25 parts of the Radix Polygoni Multiflori, 12 parts of Fructus Ligustri Lucidi, 25 parts of Radix Astragali, 10 parts of Radix Notoginseng piece, 5 parts of Rhizoma Chuanxiong, 12 parts of Caulis Spatholobi, Fructus Rosae Laevigatae 12
Part, 15 parts of Herba Taxilli, 5 parts of Radix Codonopsis, 15 parts of Fructus Corni, 15 parts of Herba Ipomoeae Cairicae, 12 parts of Fructus Lycii, 12 parts of Morinda offcinalis How, 12 parts of the Cortex Eucommiae, the Radix Paeoniae Alba
12 parts, 25 parts of Semen Cuscutae, 12 parts of Fructus Jujubae, 12 parts of Radix Rehmanniae Preparata, 12 parts of the Rhizoma Atractylodis Macrocephalae, 12 parts of the Radix Rehmanniae, 5 parts of Cornu Cervi Pantotrichum, 5 parts of deer tail.
The Chinese medicine composition makes pill, comprises the steps：
1) weigh above-mentioned each component according to formula proportion, carry out processing, dry, pulverize after sieve；
2) after sieve above-mentioned processing, medicated powder is sufficiently mixed using ripening sterilization treatment, and first temperature is brought rapidly up to 110
DEG C, 100 DEG C are subsequently slowly dropped to, obtain preparing required pill medicated powder；
3) take high-purity Mel to be put in above-mentioned medicated powder input pot in pot when being brewed into moderate, stirred, stirring is
Cool down after even, pill block, rub ball bar, pill grain with the hands.
Embodiment 3
A kind of Chinese medicine composition for treating pulpitiss, including the crude drug of following parts by weight：
20 parts of Flos Chrysanthemi, 10 parts of Maca, 13 parts of Rhizoma Polygonati, 3 parts of Radix Campylotropis Hirtella (Herba Myrsines Africanae), 18 parts of Herb Gynostemmae Pentaphylli, 15 parts of Folium Mori, 22 parts of Radix Puerariae, certainly
35 parts of pine torch, 20 parts of the Radix Polygoni Multiflori, 10 parts of Fructus Ligustri Lucidi, 20 parts of Radix Astragali, 8 parts of Radix Notoginseng piece, 4 parts of Rhizoma Chuanxiong, 10 parts of Caulis Spatholobi, Fructus Rosae Laevigatae 10
Part, 10 parts of Herba Taxilli, 5 parts of Radix Codonopsis, 12 parts of Fructus Corni, 12 parts of Herba Ipomoeae Cairicae, 10 parts of Fructus Lycii, 10 parts of Morinda offcinalis How, 10 parts of the Cortex Eucommiae, the Radix Paeoniae Alba
10 parts, 22 parts of Semen Cuscutae, 10 parts of Fructus Jujubae, 10 parts of Radix Rehmanniae Preparata, 10 parts of the Rhizoma Atractylodis Macrocephalae, 10 parts of the Radix Rehmanniae, 3 parts of Cornu Cervi Pantotrichum, 3 parts of deer tail.
The Chinese medicine composition makes sublimed preparation, comprises the steps：
1) weigh above-mentioned each component by formula proportion, carry out processing, dry, pulverize after sieve；Medicated powder after sieve is fully mixed
Close, be lyophilized into powder, be then ground to fine powder；
2) a small amount of fine powder is placed in coating pan and is rolled, Auxiliary Liquid Material on a small quantity based on water is sprayed into when rolling, formed
Tiny damp granules, add a small amount of mixed powder, roll, then jetting liquid adjuvant, repeatable operation, make sublimed preparation basic
Grain after, through screening, select spherical pellet mould of uniform size, to ball mould continue jetting liquid adjuvant, upper powder, round as a ball, screening, until
Make the little pill that particle diameter is 1.5～2mm；
3) little pill is placed in drying in oven, is then placed in coating pan, add cured powder on a small quantity, tumbling is until little
Till pellet surface light.
Embodiment 4
A kind of Chinese medicine composition for treating pulpitiss, including the crude drug of following parts by weight：
30 parts of Flos Chrysanthemi, 12 parts of Maca, 14 parts of Rhizoma Polygonati, 20 parts of Herb Gynostemmae Pentaphylli, 24 parts of Folium Mori, 25 parts of Radix Puerariae, 45 parts of Semen Cassiae, head
25 parts of crow, 25 parts of Semen Cuscutae, 12 parts of Morinda offcinalis How, 12 parts of the Cortex Eucommiae.
The Chinese medicine composition makes unguentum, comprises the steps：
1) weigh above-mentioned each component by formula proportion, carry out processing, dry, pulverize after sieve；Medicated powder after sieve is fully mixed
Close, do after spray vinegar on the mixture and fry, the medicine of fried dry is exposed to the sun after 12h, fine powder is ground into and is sieved；
2) in the mixed-powder for sieving according to weight 1:4 ratio adds Oleum sesami and Colophonium to be tuned into pasty ointment.
Embodiment 5
A kind of Chinese medicine composition for treating pulpitiss, including the crude drug of following parts by weight：
15 parts of Flos Chrysanthemi, 8 parts of Maca, 12 parts of Rhizoma Polygonati, 15 parts of Herb Gynostemmae Pentaphylli, 12 parts of Folium Mori, 20 parts of Radix Puerariae, 30 parts of Semen Cassiae, head
10 parts of crow, 20 parts of Semen Cuscutae, 8 parts of Morinda offcinalis How, 8 parts of the Cortex Eucommiae.
The Chinese medicine composition makes decoction, comprises the steps：Above-mentioned each component is weighed by formula proportion, 5-10 is added
The water of times raw material components total amount, with 10-20 minutes are cooked by slow fire after being boiled by fire, filter and remove residue is obtained final product.
Embodiment 6
A kind of Chinese medicine composition for treating pulpitiss, including the crude drug of following parts by weight：
25 parts of Flos Chrysanthemi, 10 parts of Maca, 13 parts of Rhizoma Polygonati, 18 parts of Herb Gynostemmae Pentaphylli, 20 parts of Folium Mori, 22 parts of Radix Puerariae, 40 parts of Semen Cassiae, head
10 parts of crow, 22 parts of Semen Cuscutae, 10 parts of Morinda offcinalis How, 10 parts of the Cortex Eucommiae.
The Chinese medicine composition makes powder, comprises the steps：Above-mentioned each component is weighed by formula proportion, big gun is carried out
System, dry, pulverize after sieve；Medicated powder after sieve is sufficiently mixed, powder is lyophilized into, fine powder is then ground to, is mixed thoroughly.
Embodiment 7
Clinical laboratory data：
1st, inventor collects 250 pulpitiss patients, male 130, women altogether between in October, -2016 in October, 2013
120, age 20-60 year, course of disease 1-5.It is randomly divided into：Treatment A groups 100, treatment B groups 100, blank group 50.Three
There was no significant difference for the data such as group age, the state of an illness, with comparability.
2nd, test method
, according to decoction obtained in specific embodiment 1, the morning and evening is each once for the oral present invention for the treatment of A groups.The course for the treatment of 30 days.
, according to decoction obtained in specific embodiment 5, the morning and evening is each once for the oral present invention for the treatment of B groups.The course for the treatment of 30 days.
Blank group oral placebo capsule, sooner or later respectively once.The course for the treatment of 30 days.
3rd, criterion of therapeutical effect and therapeutic outcome
Efficacy determination：Using 4 grades of standards.
Recovery from illness：Symptom all disappears, and diet sleep is normal, and cold and hot, diet stimulates without any pain, 2 years after treatment
Below do not recur；
Effective：Cardinal symptom disappears substantially, and after occasionally having thermostimulation, periodontal is uncomfortable, does not recur within more than 1 year after treatment；
Take a turn for the better：Cardinal symptom disappears substantially, and after occasionally having thermostimulation, periodontal is uncomfortable, slightly recurs within stopping treatment 1 year, but
Treat and voluntarily recover；
Invalid：Though toothache symptom has mitigation, caloric stimulation still to aggravate disease, vexed, insomnia, stop treatment half a year interior still
Multiple relapse, must go treatment again.
Treatment statistics are shown in Table 1.
1 three groups of comparitive studies of table
| Group | N | Recovery from illness | Effective | Take a turn for the better | Invalid | Total effective rate | Untoward reaction |
| Treatment A groups | 100 | 90 (90%) | 6 (6%) | 4 (4%) | 0 (0%) | 100% | 0 |
| Treatment B groups | 100 | 95 (95%) | 5 (5%) | 0 (0%) | 0 (0%) | 100% | 0 |
| Blank group | 50 | 0 | 0 | 6 (12%) | 44 (88%) | 12% | 0 |
Can find out from the table, the effective percentage of the present invention is adopted 1 made medicament cure rate of embodiment for 90%, adopted up to 100%
95% is more up to 5 made medicament of embodiment, and without any side effects to patient, three big routine tests and hepatic and renal function detection
No abnormal.
4th, take effect speed
Take effect judgement：Using 3 grades of standards.
I levels：Toothache all disappears；
II levels：Toothache is basic to disappear, and after occasionally having thermostimulation, periodontal is uncomfortable；
III level：Though toothache has mitigation, still pain is endlessly for thermostimulation to the cold.
2 two groups of table take effect speed ratio compared with
| Group | I levels | II levels | III level | |
| Treatment A groups | Averagely take effect duration | 2.5h | 1.5h | 30min |
| Treatment B groups | Averagely take effect duration | 2h | 1h | 20min |
Can be seen that all to disappear using the toothache of 1 made medicament of embodiment from the table and averagely need 2.5 hours, using reality
Applying the toothache of 5 made medicament of example and all disappearing averagely needs 2 hours.Illustrate that Chinese medicine composition proposed by the present invention takes effect speed soon,
Can conveniently and efficiently alleviate, release pulpitiss patient suffering.
Embodiment 8
Model case：
Case 1：Patient Lee so-and-so, man 40 years old, has a toothache 5 days, is diagnosed as acute pulpitiss on inspection, oral medicine of the present invention
Thing is treated, and after three hours, pain all disappears, and after a course for the treatment of, symptom all disappears, and does not recur so far.
Case 2：Patient's week so-and-so, female, 44 years old, gingival swelling and pain 2 days was diagnosed as acute pulpitiss, oral medicine of the present invention
Treatment, after two hours, pain all disappears, and after a course for the treatment of, symptom all disappears, and does not recur so far.
Case 3：Patient Zheng, female 50 years old, have long-term hot and cold stimulation pain medical history, are diagnosed as chronic pulpitiss, mouth
Clothes Drug therapy of the present invention, after two hours, pain all disappears, and after a course for the treatment of, symptom all disappears, and does not recur so far.
Conclusion：Produce between each component of the present invention and cooperate, synergism so that the curative effect of each component reaches most
Excellent, antiinflammatory, antihistaminic and anaerobe can not only be suppressed so that the inflammation of pulp tissue is able to control rapidly and eliminate, also
Pulp tissue's quick recovery can be promoted and recover normal physiological function early.The various preparation taking conveniences of the present invention, nontoxic pair
Effect, by dredge the meridian passage and adjusts immunologic function, improves the body constitution of patient, strengthen autoimmunity, preferably reach
To healing rehabilitation efficacy.
Obviously, the above embodiment of the present invention is only intended to clearly illustrate example of the present invention, and is not right
The restriction of embodiments of the present invention, for those of ordinary skill in the field, may be used also on the basis of the above description
To make other changes in different forms, all of embodiment cannot be exhaustive here, every belong to this
Bright technical scheme extended obvious change or change still in protection scope of the present invention row.
Claims (10)
1. a kind of Chinese medicine composition for treating pulpitiss, it is characterised in that including the crude drug of following parts by weight：Flos Chrysanthemi
15～30 parts, 8～12 parts of Maca, 12～14 parts of Rhizoma Polygonati, 2～4 parts of Radix Campylotropis Hirtella (Herba Myrsines Africanae), 15～20 parts of Herb Gynostemmae Pentaphylli, 12～24 parts of Folium Mori, Pueraria lobota
20～25 parts of root, 30～45 parts of Semen Cassiae, 10～25 parts of the Radix Polygoni Multiflori, 8～12 parts of Fructus Ligustri Lucidi, 10～25 parts of Radix Astragali, Radix Notoginseng piece 6～10
Part, 2～5 parts of Rhizoma Chuanxiong, 8～12 parts of Caulis Spatholobi, 8～12 parts of Fructus Rosae Laevigatae, 10～15 parts of Herba Taxilli, 2～5 parts of Radix Codonopsis, Fructus Corni 10
～15 parts, 10～15 parts of Herba Ipomoeae Cairicae, 8～12 parts of Fructus Lycii, 8～12 parts of Morinda offcinalis How, 8～12 parts of the Cortex Eucommiae, 8～12 parts of the Radix Paeoniae Alba, Herba cuscutae
20～25 parts of son, 8～12 parts of Fructus Jujubae, 8～12 parts of Radix Rehmanniae Preparata, 8～12 parts of the Rhizoma Atractylodis Macrocephalae, 8～12 parts of the Radix Rehmanniae, 2～5 parts of Cornu Cervi Pantotrichum, deer tail 2
～5 parts.
2. a kind of Chinese medicine composition for treating pulpitiss according to claim 1, it is characterised in that the Chinese medicine group
Compound includes the crude drug of following parts by weight：15～30 parts of Flos Chrysanthemi, 8～12 parts of Maca, 12～14 parts of Rhizoma Polygonati, Herb Gynostemmae Pentaphylli 15～
20 parts, 12～24 parts of Folium Mori, 20～25 parts of Radix Puerariae, 30～45 parts of Semen Cassiae, 10～25 parts of the Radix Polygoni Multiflori, 20～25 parts of Semen Cuscutae, bar
8～12 parts of halberd, 8～12 parts of the Cortex Eucommiae.
3. a kind of Chinese medicine composition for treating pulpitiss according to claim 1, it is characterised in that the Chinese medicine group
Compound includes the crude drug of following parts by weight：15 parts of Flos Chrysanthemi, 8 parts of Maca, 12 parts of Rhizoma Polygonati, 15 parts of Herb Gynostemmae Pentaphylli, 12 parts of Folium Mori, Pueraria lobota
20 parts of root, 30 parts of Semen Cassiae, 10 parts of the Radix Polygoni Multiflori, 20 parts of Semen Cuscutae, 8 parts of Morinda offcinalis How, 8 parts of the Cortex Eucommiae.
4. a kind of Chinese medicine composition for treating pulpitiss according to claim 1, it is characterised in that the Chinese medicine group
Compound can be made into pill, sublimed preparation, powder, tablet, unguentum or decoction.
5. a kind of preparation method for treating the Chinese medicine composition of pulpitiss as described in claim 1-4, it is characterised in that
The Chinese medicine composition makes pill, comprises the steps：
1) weigh above-mentioned each component according to formula proportion, carry out processing, dry, pulverize after sieve；
2) after sieve above-mentioned processing, medicated powder is sufficiently mixed using ripening sterilization treatment, and first temperature is brought rapidly up to 110 DEG C, with
After be slowly dropped to 100 DEG C, obtain preparing required pill medicated powder；
3) take high-purity Mel to be put in above-mentioned medicated powder input pot in pot when being brewed into moderate, stirred, after stirring
Ball bar, pill grain are rubbed in cooling, pill block with the hands.
6. a kind of preparation method for treating the Chinese medicine composition of pulpitiss as described in claim 1-4, it is characterised in that
The Chinese medicine composition makes sublimed preparation, comprises the steps：
1) weigh above-mentioned each component by formula proportion, carry out processing, dry, pulverize after sieve；Medicated powder after sieve is sufficiently mixed, is frozen
Powder is done into, fine powder is then ground to；
2) a small amount of fine powder is placed in coating pan and is rolled, Auxiliary Liquid Material on a small quantity based on water is sprayed into when rolling, formed tiny
Damp granules, add a small amount of mixed powder, roll, then jetting liquid adjuvant, repeatable operation make the basic granules of sublimed preparation
Afterwards, through screening, spherical pellet mould of uniform size is selected, continues jetting liquid adjuvant to ball mould, upper powder, round as a ball, screening, until system
Into the little pill that particle diameter is 1.5～2mm；
3) little pill is placed in drying in oven, is then placed in coating pan, add cured powder on a small quantity, tumbling is until little pill
Till surface-brightening.
7. a kind of preparation method for treating the Chinese medicine composition of pulpitiss as described in claim 1-4, it is characterised in that
The Chinese medicine composition makes powder, comprises the steps：Above-mentioned each component is weighed by formula proportion, carried out processing, dried, powder
Sieve after broken；Medicated powder after sieve is sufficiently mixed, powder is lyophilized into, fine powder is then ground to, is mixed thoroughly.
8. a kind of preparation method for treating the Chinese medicine composition of pulpitiss as described in claim 1-4, it is characterised in that
The Chinese medicine composition makes tablet, comprises the steps：
1) weigh above-mentioned each component by formula proportion, carry out processing, dry, pulverize after sieve；Medicated powder after sieve is sufficiently mixed, is mixed
Add after conjunction and enter granulation in granulator；
2) gained granule is placed in airpillow-dry agent and is dried process；
3) dried granule is put into pelletizing machine granulate, to granulate after hybrid particles carry out sheeting operation.
9. a kind of preparation method for treating the Chinese medicine composition of pulpitiss as described in claim 1-4, it is characterised in that
The Chinese medicine composition makes unguentum, comprises the steps：
1) weigh above-mentioned each component by formula proportion, carry out processing, dry, pulverize after sieve；Medicated powder after sieve is sufficiently mixed,
Do after spray vinegar on mixture and fry, the medicine of fried dry is exposed to the sun after 12h, fine powder is ground into and is sieved；
2) in the mixed-powder for sieving according to weight 1:4 ratio adds Oleum sesami and Colophonium to be tuned into pasty ointment.
10. a kind of preparation method for treating the Chinese medicine composition of pulpitiss as described in claim 1-4, its feature exist
In the Chinese medicine composition makes decoction, comprises the steps：Above-mentioned each component is weighed by formula proportion, 5-10 times of original is added
The water of material component total amount, with 10-20 minutes are cooked by slow fire after being boiled by fire, filter and remove residue is obtained final product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107115587A (en) * | 2017-05-15 | 2017-09-01 | 河南省中医院（河南中医学院第二附属医院） | Analgesic therapeutic apparatus for treating cancer pain |
| ES2715014A1 (en) * | 2017-11-30 | 2019-05-31 | Shanghai Jishuai Bio Tech Co Ltd | MEDICAL PRODUCT OF MACA (Machine-translation by Google Translate, not legally binding) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641384A (en) * | 2012-04-20 | 2012-08-22 | 王莲芬 | Chinese patent medicine for treating pulpitis |
| CN104721283A (en) * | 2013-12-18 | 2015-06-24 | 罗启东 | Medicament for treating pulpitis |
-
2017
- 2017-01-03 CN CN201710002659.4A patent/CN106491971A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641384A (en) * | 2012-04-20 | 2012-08-22 | 王莲芬 | Chinese patent medicine for treating pulpitis |
| CN104721283A (en) * | 2013-12-18 | 2015-06-24 | 罗启东 | Medicament for treating pulpitis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107115587A (en) * | 2017-05-15 | 2017-09-01 | 河南省中医院（河南中医学院第二附属医院） | Analgesic therapeutic apparatus for treating cancer pain |
| ES2715014A1 (en) * | 2017-11-30 | 2019-05-31 | Shanghai Jishuai Bio Tech Co Ltd | MEDICAL PRODUCT OF MACA (Machine-translation by Google Translate, not legally binding) |
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Application publication date: 20170315 |