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CN106178155A - Infusion container interface multi-pharmaceutics the most directly can joined and infusion vessel - Google Patents

Infusion container interface multi-pharmaceutics the most directly can joined and infusion vessel Download PDF

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Publication number
CN106178155A
CN106178155A CN201610563759.XA CN201610563759A CN106178155A CN 106178155 A CN106178155 A CN 106178155A CN 201610563759 A CN201610563759 A CN 201610563759A CN 106178155 A CN106178155 A CN 106178155A
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CN
China
Prior art keywords
nozzle
prescription
injectable powder
raised line
make
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Granted
Application number
CN201610563759.XA
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Chinese (zh)
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CN106178155B (en
Inventor
文兰兰
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HUNAN YIKE MEDICINAL PACKAGING MATERIAL TECHNOLOGY Co Ltd
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HUNAN YIKE MEDICINAL PACKAGING MATERIAL TECHNOLOGY Co Ltd
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Priority to CN201610563759.XA priority Critical patent/CN106178155B/en
Publication of CN106178155A publication Critical patent/CN106178155A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1406Septums, pierceable membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1412Containers with closing means, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1475Inlet or outlet ports

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The invention discloses a kind of infusion container interface can the most directly joined multi-pharmaceutics, it includes that make up a prescription nozzle (22), aqueous injection of substrate (21), injectable powder makes up a prescription nozzle (23), transfusion nozzle (24) and puncture needle (25);Substrate (21) is that injectable powder makes up a prescription nozzle (22) and the connecting plate of nozzle (24) of infusing, and aqueous injection makes up a prescription nozzle (23) and is connected with nozzle (24) of infusing;The make up a prescription bottom of nozzle (22) of injectable powder is provided with union joint (221);The top of union joint (221) is provided with every liquid sheet (228);Puncture needle (25) be arranged on injectable powder make up a prescription nozzle (22) dispensing cavity in;Injectable powder nozzle (22) inwall that makes up a prescription is provided with the first location structure and the second location structure.It can be saved medical worker, save sterilizing article, realizes " transparent consumption " and " understand treatment ", realizes multi-pharmaceutics and repeatedly make up a prescription, reduce pollutions, be suitable for product line production, effectively seal.

Description

Infusion container interface multi-pharmaceutics the most directly can joined and infusion vessel
Technical field
The present invention relates to a kind of medical supplies, a kind of infusion container interface multi-pharmaceutics the most directly can joined And infusion vessel.
Background technology
As Figure 1-5, when current people transfusion needs the injectable powder that use cillin bottle 3 is filled, it is usually and first uses pin Cylinder 4 from infusion vessel body 1(Fig. 1, shown in 5 for transfusion bag, it is of course also possible to be infusion bottle) in extract out some liquid (as Shown in Fig. 1, liquid is generally normal saline, G/W etc.), then inject liquid into equipped with in the cillin bottle 3 of injectable powder (as Shown in Fig. 2, it is also possible to be powder pin bottle), then shake the injectable powder in equal cillin bottle 3 so that injectable powder medicine and the liquid in cillin bottle 3 Body mix homogeneously (as shown in Figure 3), then through syringe 4, by medicinal liquid, (injectable powder medicine is formed with the liquid in cillin bottle 3 Mixing liquid) extract (as shown in Figure 4) out, finally the medicinal liquid in syringe 4 is injected in infusion vessel body 1, thus can be by defeated Medicinal liquid in liquid container body 1 carries out infusion (injection system of medicinal liquid automatic transport) to human body.It addition, for cillin bottle 3 institute The lyophilized injectable powder of dress or aqueous injection etc. are also substantially the above-mentioned first extraction of employing (directly extracting out or by extracting out after liquid mixing) Medicine, reinject the method for infusion vessel body 1 and carry out mixed medicine.Although this mode can be by medicine and infusion vessel body 1 Liquid mixing, is then conveyed into human body, but uses this dispensing method, there is problems in that
1. needing repeatedly to mix medicine, in general, extracting liquid from infusion vessel body 1 out often needs to medicine mixed in cillin bottle 3 It is repeated several times by just can being mixed in infusion vessel body 1 by whole injectable powder.
First, above-mentioned mixed medicine operating process is relatively time-consuming, laborious, take consumptive material, such as syringe, ethanol, absorbent cotton etc..
3. there is potential safety hazard.During above-mentioned mixed medicine, whole medicinal liquid does not completes under a closed environment, non- Much more very the air of outside is injected in cillin bottle 3 and infusion vessel body 1 by Chang Rongyi, exist under generic condition in air Various dust, pathogenic bacteria, enter back into human body after being mixed into liquid medicine injection, can bring the most serious malpractice.
4. repeatedly interted by syringe needle on infusion vessel body 1 interface, during mixed medicine and transfusion, all there may exist and let out Leakage, the risk infected.
Currently also there is the structure of making up a prescription being provided with mixed medicine glass in transfusion bag, such as please CN 105232329 A in Chinese patent (patent name: medicine mixer, hard double nip and transfusion flexible bag), but it is primarily present following problem.
1., after cillin bottle 3 card gets on, it is stuck, can not take, it is impossible in infusion vessel body 1, allocate more than the second into again Medicine, needing to inject (infusion) two or more medicine for prescription can not use simultaneously.
2. diaphragm seal seals mixed medicine glass so that the sealing structure non insurance of mixed medicine glass, at present without detection diaphragm seal and mixed medicine Whether cup has been truly realized sealing, there is serious potential safety hazard.
3. can only carry out a kind of dosage form to make up a prescription, it is difficult to carry out injectable powder and the multiple dosage form of aqueous injection is made up a prescription.
Sealing uses easily tore film, and at present the whole world welding PP material and film, there is no reliable detection equipment, it is impossible to guarantee The encapsulant of 100% in expiration date of drug.
In addition to above-mentioned interpolation injectable powder medicine is infused, sometimes also need to add aqueous injection medicine is infused. When at present aqueous injection medicine (the liquid liquid medicine that ampoule bottle is contained) is carried out transfusion injection, the most directly extract peace out with syringe The liquid liquid medicine that small jar bottle is contained, mouth identical with powder for injecta entrance in infusion vessel injects in infusion vessel, so can There is leakage, need the problems such as sterilization, and also liquid medicine can not be added at any time in midway, i.e. can only deposit in front injection of first infusing In deficiencies such as limited, dangerous, troubles.
Summary of the invention
It is an object of the invention to overcome the above-mentioned deficiency of prior art to provide one can multi-pharmaceutics the most directly be joined Infusion container interface and infusion vessel, its can save medical worker, save a large amount of sterilizing article, realization " transparent consumption " and " understand treatment ", realize multi-pharmaceutics and repeatedly make up a prescription, reduce secondary pollution and improve and use the safety of medicine personnel, can be suitable for Pharmaceutical factory production line produces, can ensure the medicine sealing in effect duration.
The technical scheme is that a kind of infusion container interface can the most directly joined multi-pharmaceutics, it includes base Make up a prescription nozzle, aqueous injection of plate, injectable powder makes up a prescription nozzle, transfusion nozzle and puncture needle;Substrate is that injectable powder makes up a prescription nozzle and the connection of nozzle of infusing Plate, aqueous injection makes up a prescription nozzle (23) and is connected with nozzle (24) of infusing;
The make up a prescription inner chamber of nozzle of injectable powder is injectable powder medicine dispensing cavity, is used for assigning cillin bottle, injectable powder to make up a prescription the dispensing cavity of nozzle Adapt with the head configuration of cillin bottle;The make up a prescription bottom of nozzle of injectable powder is provided with union joint, and union joint is hollow tubular, injectable powder The nozzle that makes up a prescription is connected through head and is connected with substrate, and substrate is provided with the injectable powder through hole that the hollow with union joint is connected;Even The top of joint is provided with every liquid sheet, injectable powder makes up a prescription nozzle and union joint is isolated every liquid sheet;Injectable powder makes up a prescription the other end of nozzle For opening;The inner chamber of union joint is medicine liquid channel;
Puncture needle be arranged on injectable powder make up a prescription nozzle dispensing cavity in;Injectable powder nozzle upper inside wall position of making up a prescription is provided with and puncture needle The first location structure that demarcation strip matches, puncture needle can be blocked and the most locked make up a prescription nozzle at injectable powder by the first location structure The position in interior top portion;The injectable powder nozzle inwall that makes up a prescription is additionally provided with the second location structure, the first location structure near the position of pad Puncture needle can be stuck in injectable powder make up a prescription in nozzle the position in portion on the lower.
The further technical scheme of the present invention is: described puncture needle includes needle tubing and demarcation strip;Needle tubing includes winding the needle tube With lower needle tubing;Winding the needle tube is connected with lower needle tubing, and its interior medicament channel is connected;Demarcation strip is plate shape, and it is arranged on pin Pipe and lower needle tubing connection;Demarcation strip is provided with more than one clean-out opening;The head of winding the needle tube is pointed puncturing head, wears The top of tartar is real core, and described puncturing head is cone;The side of winding the needle tube is provided with more than one at puncturing head Ditch through hole;Winding the needle tube is or/and lower needle interior wall is circumferentially equipped with two to four reinforcements.
The present invention further technical scheme is: the first described location structure include on first raised line and first time convex Bar, forms draw-in groove between raised line and first time raised line on first, raised line on first is or/and first time raised line is to be laid in injectable powder The annular on nozzle inwall of making up a prescription raised line or discontinuous multiple projection continuously, demarcation strip can be stuck in the first location structure;The Two location structures include that the make up a prescription bottom of nozzle of end raised line, end raised line and injectable powder is spaced a distance, distance size and demarcation strip Thickness adapts;End raised line is to be laid in annular raised line or the scattered multiple projection continuously that injectable powder makes up a prescription on nozzle inwall.
The present invention further technical scheme is: raised line on described first is or/and the internal diameter score of first time raised line Dividing plate external diameter is little;The internal diameter of end raised line is less than demarcation strip external diameter;Upper raised line, first time raised line and end raised line are for make up a prescription with injectable powder Nozzle is the structure that integral type is molded.
The most further technical scheme of the present invention is: described injectable powder make up a prescription nozzle opening on to be also associated with powder pin easy Lid, the powder pin easy-open lid nozzle that makes up a prescription with injectable powder is drawn to be connected by welding.
The further technical scheme of the present invention is: described transfusion nozzle is tubulose, and its lower end is connected with substrate, on substrate It is provided with the liquid through-hole that the hollow with nozzle of infusing is connected;It is additionally provided with transfusion easy-open lid on the free end of transfusion nozzle, infuses easy-to-draw Cover and the free end phase welding of transfusion nozzle;It is additionally provided with sealing gasket B and inner cap B in transfusion easy-open lid.
The further technical scheme of the present invention is: the described aqueous injection nozzle that makes up a prescription is tubulose, and it is located at transfusion nozzle one side, Its in container body prepare aqueous injection medicine, aqueous injection make up a prescription nozzle inner chamber with transfusion nozzle intracavity inter-connection;Aqueous injection makes up a prescription Being additionally provided with aqueous injection easy-open lid on the free end of nozzle, aqueous injection easy-open lid and aqueous injection make up a prescription the free end phase welding of nozzle.
The further technical scheme of the present invention is: described aqueous injection make up a prescription nozzle axis with the horizontal ± degree folder Angle α, i.e. α=± °;Sealing gasket A and inner cap A it is additionally provided with in aqueous injection easy-open lid.
The further technical scheme of the present invention is: make up a prescription nozzle, aqueous injection of described substrate, injectable powder makes up a prescription nozzle and transfusion nozzle The structure being molded for integral type;Winding the needle tube, lower needle tubing and demarcation strip are the structure that integral type is an integrally-molded;Winding the needle tube It is provided with protection set;Every liquid sheet and the structure that union joint is that integral type is molded;The make up a prescription bottom of nozzle of injectable powder equipped with pad, Pad is rubber cushion.
The present invention another solution is that a kind of infusion vessel can the most directly joined multi-pharmaceutics, and it includes container Body and interface;Interface is welded on container body by its substrate;Container body is transfusion bag or infusion bottle.
The present invention compared with prior art has a characteristic that
1. the present invention is truly realized flow of infusate and directly joins, once make up a prescription from existing one within about 3 minutes, be reduced to 20 seconds within; Directly join formula to mix medicine and decrease medical personnel's workload 60%, save medical worker, such as, the doctor of original 30 nurses of needs Institute, may decrease to about 10 people.
2. can save a large amount of sterilizing article, save the resource of preciousness, reduced cost of curing the disease.Such as it is no longer necessary to make The disposable syringe with ethanol, cotton swab infusion vessel carried out disinfection and make up a prescription.
3. patient is it will be clear that oneself have input any medicine, not only realizes " transparent consumption ", it is often more important that Patient is it is known that oneself employ any medicine and treated actually.
4. can realize repeatedly making up a prescription, and an other medicine can be increased in the difference transfusion stage as required.Existing Having technology to use folder bottle cover, powder pin bottle can only once make up a prescription certain limitation, and the present invention by press from both sides bottle cover change into right Puncture needle carries out the clamping of upper and lower two positions, i.e. puncture needle and is respectively at two different settling positions, both before and after puncturing Will not tamper, it is also possible to promote as required;Without by stuck for powder pin bottle (cillin bottle) after puncture, conveniently by powder pin after making up a prescription Bottle takes off, and is used for joining next powder pin bottle medicine, and fundamentally solving can only be by once making up a prescription as the problem repeatedly made up a prescription, from root The quality and speed made up a prescription is solved in basis.
The most whole process of making up a prescription is under sealing, aseptic state and carries out, and the secondary reducing medical personnel's operating process is dirty Dye;Improve medical safety;Stop the sensitization etc. that medical personnel cause because of contact medicinal liquid when making up a prescription simultaneously, improve Use the safety of medicine personnel.
6. existing product is only suitable for pharmaceutical factory hard double nip production line, and by a definite limitation, and product of the present invention can be suitable for medicine Factory's single, double interface soft bag, plastic bottle infusion production line.
The most existing cup sealing of making up a prescription uses easily tore film, and at present the whole world welding PP material and film, there is no and examine reliably Measurement equipment, it is impossible to ensure the sealing of 100% in expiration date of drug, therefore use film material does sealing, has certain sealing Detection lacuna risk, and easy-open lid of the present invention welding (welding) mode, use material and maturation that the nozzle that makes up a prescription with injectable powder is identical Production technology, this sealing means may insure that the memory cycle of medicine, fundamentally ensure that close in effect duration of medicine Feng Xing.
8. multi-pharmaceutics the most directly can be joined, say, that can be before transfusion, by more than one cillin bottle In powder medicine administered by injection thing be formulated in infusion bottle, the aqueous injection medicine in more than one ampoule bottle is formulated in infusion bottle;Also According to the needs for the treatment of, the powder medicine administered by injection thing in more than one cillin bottle can be formulated in infusion bottle in infusion process, Aqueous injection medicine in more than one ampoule bottle is formulated in infusion bottle.
Below in conjunction with the drawings and specific embodiments, the detailed construction of the present invention is further described.
Accompanying drawing explanation
Infusion vessel and syringe when Fig. 1 is to extract liquid in existing infusion mode from infusion vessel (transfusion bag) Structural representation;
Fig. 2 is to extract cillin bottle and syringe when liquid injects cillin bottle in existing infusion model from infusion vessel (transfusion bag) Structural representation;
Fig. 3 is the structural representation in existing infusion mode equipped with medicine Yu the cillin bottle of the mixture of liquid;
Fig. 4 is the structure in existing infusion mode from cillin bottle extraction medicine with cillin bottle during the mixture of liquid with syringe Schematic diagram;
Infusion vessel when Fig. 5 is, in existing infusion mode, the mixture of the medicine in syringe with liquid is injected infusion vessel Structural representation with syringe;
Fig. 6 is the structural representation of the interface of the present invention;
Fig. 7 is that Fig. 6 is along the partial enlarged drawing in the range of A line;
Fig. 8 is that make up a prescription nozzle, aqueous injection of the substrate of the interface of the present invention, injectable powder makes up a prescription nozzle, the structural representation of transfusion nozzle;
Fig. 9 is the structural representation of the protection set of the puncture needle of the present invention;
Figure 10 is the structural representation of the puncture needle of the present invention;
Figure 11 is the structural representation after the interface of the present invention is mounted with cillin bottle;
Figure 12 is that Figure 11 is along the partial enlarged drawing in the range of B line;
Figure 13 is the infusion vessel of present invention structural representation when preparing injectable powder (when cillin bottle is plugged);
Figure 14 is the structural representation during infusion vessel use state of the present invention.
Detailed description of the invention
Embodiment 1
As shown in Fig. 6-14: a kind of infusion vessel can the most directly joined multi-pharmaceutics, it includes container body 1 and interface 2;Hold Body 1 is transfusion bag (such as Figure 13, shown in 14, naturally it is also possible to for infusion bottle), and it is used for containing medicinal liquid.
As shown in figs 6-12, interface 2 includes that make up a prescription nozzle 22, aqueous injection of substrate 21, injectable powder makes up a prescription nozzle 23, transfusion nozzle 24 and Puncture needle 25;Substrate 21 makes up a prescription nozzle 22 and the connecting plate of nozzle 24 of infusing for injectable powder.
Make up a prescription nozzle 22, aqueous injection of substrate 21, injectable powder makes up a prescription nozzle 23 and transfusion nozzle 24 generally uses integral type to be molded.
Interface 2 is welded on container body 1 by its substrate 21.
Injectable powder makes up a prescription nozzle 22 overall cup-shaped (can also weighing bucket shape or tubular), and its inner chamber is that injectable powder medicine makes up a prescription Chamber, is used for assigning cillin bottle 3(as shown in figure 11), the injectable powder dispensing cavity of nozzle 22 that makes up a prescription is fitted mutually with the head configuration of cillin bottle 3 Should;The make up a prescription bottom of nozzle 22 of injectable powder is provided with union joint 221, and union joint 221 is hollow tubular, and injectable powder makes up a prescription nozzle 22 by it Union joint 221 is connected with substrate 21, and substrate 21 is provided with the injectable powder through hole 211 that the hollow with union joint 221 is connected;Powder The make up a prescription bottom of nozzle 22 of injection is rubber cushion equipped with pad 222, pad 222, (makes up a prescription nozzle 22 with injectable powder in the top of union joint 221 Junction) it is provided with every liquid sheet 228, every the structure that liquid sheet 228 is molded with union joint 221 usually integral type, relatively thin, it is possible to To be barrier film, to facilitate puncture, pad 222 and injectable powder made up a prescription nozzle 22 and union joint 221 is isolated, to protect every liquid sheet 228 Medicinal liquid that card communicates with union joint 221 before puncture (medicinal liquid in container body 1, such as Figure 13, shown in 14) can make up a prescription with injectable powder Nozzle 22 is isolated, and forms sealing effectiveness;Injectable powder makes up a prescription the other end (i.e. top, with the angle shown in Fig. 6) of nozzle 22 as opening End;The inner chamber of union joint 221 is medicine liquid channel.
As shown in Figure 10, puncture needle 25 includes needle tubing and demarcation strip 253;Needle tubing includes winding the needle tube 251 and lower needle tubing 252; Winding the needle tube 251 is connected with lower needle tubing 252, and its interior medicament channel is connected (being i.e. monolithically fabricated hollow tubular);Demarcation strip 253 For plate shape, it installs (installing) in winding the needle tube 251 and lower needle tubing 252 connection;Demarcation strip 253 be provided with more than one clearly Hole flushing 2531, is usually and is circumferentially equipped with two to four clean-out openings 2531 on described demarcation strip 253;Winding the needle tube 251 Head is pointed puncturing head 2511, and the top of puncturing head 2511 is real core, described puncturing head 2511 usually cone;On The side of needle tubing 251 is provided with more than one ditch through hole 2512, ditch through hole 2512 generally two to four at puncturing head 2511 Individual;Winding the needle tube 251 is or/and lower needle tubing 252 inwall is circumferentially equipped with two to four reinforcements.Winding the needle tube 251, lower needle tubing 252 Generally use with demarcation strip 253 and be disposably an integrally-molded.
Puncture needle 25 be arranged on injectable powder make up a prescription nozzle 22 dispensing cavity in, its winding the needle tube 251 be provided with protection set 254, protect Sheath 254 can prevent winding the needle tube 251 from deforming and affecting puncture, it is also possible to prevents the head of winding the needle tube 251 from polluting.
The injectable powder demarcation strip that nozzle 22 upper inside wall position (for the orientation of Fig. 6) is provided with puncture needle 25 that makes up a prescription matches The first location structure closed, as shown in Figure 6,7, the first location structure includes raised line 226 and first time raised line 223 on first, the Forming draw-in groove 224 on one between raised line 226 and first time raised line 223, certainly, raised line 226 on first is or/and first time raised line 223 can be to be laid in the annular raised line continuously that injectable powder makes up a prescription on nozzle 22 inwall, it is also possible to be discontinuous (the most circumferentially cloth The scattered multiple projections put, belong to same design, belong to the scope of protection of the invention), raised line 226 on first is or/and Once the height of raised line 223 projection with puncture needle 25 demarcation strip 253 can (medical worker be with hands slightly inwards under a certain pressure Pressure) pass through, it is common that raised line 226 on first is or/and the internal diameter of first time raised line 223 more slightly smaller than demarcation strip external diameter (1-3 millimeter) Ensure that this ferrule structure, make demarcation strip 253 can be stuck in the first location structure (raised line 226 and first on first In draw-in groove 224 between lower raised line 223), puncture needle 25 would not vertically (above-below directions of Fig. 6,13,14) mobile (namely Play up and down), during use, people also will not be stoped to pressing to pad 222 by puncture needle 25, the i.e. first location structure is only to wearing Pricker 25 positions rather than locked puncture needle 25, namely the first location structure is the clamping that can block puncture needle 25 driving Structure.
As depicted in figs. 11-12, injectable powder nozzle 22 inwall that makes up a prescription is additionally provided with the second location structure near the position of pad 222, Second location structure includes that the make up a prescription bottom of nozzle 22 of end raised line 225, end raised line 225 and injectable powder is spaced a distance, distance size Adapt with the thickness of demarcation strip 253, so end raised line 225 and injectable powder make up a prescription nozzle 22 bottom between also formed one card Groove structure;After realizing puncturing, demarcation strip 253 moves and is stuck in end raised line 225, so to the make up a prescription bottom of nozzle 22 of injectable powder Puncture needle 25 would not slip out, it is ensured that the cillin bottle 3 of coupled handstand will not slip out (such as Figure 14 during transfusion Shown in), i.e. the internal diameter of end raised line 225 more slightly smaller than demarcation strip 223 external diameter (1-3 millimeter);The height of end raised line 225 projection to ensure Demarcation strip 253 slightly firmly just can be pressed into inside end raised line 225 and (i.e. cross end raised line 225) by medical worker, and ensures cillin bottle Will not drop out together with puncture needle 25 during transfusion;End raised line 225 is to be laid in injectable powder to make up a prescription the ring on nozzle 22 inwall The continuous raised line of shape or scattered multiple projection.
222, first time raised line 223 of upper raised line and end raised line 225 are generally and injectable powder makes up a prescription nozzle 22 for integral type injection The structure become.
First location structure and the second location structure are substantially to build a kind of cassette knot at injectable powder nozzle 22 inwall that makes up a prescription Structure, it can block puncture needle 25, not allow it tamper up and down, its be also puncture needle 25 can be promoted (medical worker somewhat uses Power) structure.
Injectable powder make up a prescription nozzle 22 opening on be also associated with powder pin easy-open lid 227(as shown in Figure 6), powder pin easy-open lid 227 is a kind of easy-open lid, and powder pin easy-open lid 227 is provided with powder pin easy handle 2271(and includes strip, the pull handle arrangement such as ring-type), Powder pin easy-open lid 227 nozzle 22 that makes up a prescription with injectable powder is connected by welding, it is achieved seal, due to powder pin easy-open lid 227 and powder pin The agent nozzle 22 that makes up a prescription is the thickest, so commaterial can be used to make, such welding can improve sealing effectiveness, and conveniently carries out Sealing detection, more far better than sealing the make up a prescription opening effect of nozzle 22 of injectable powder by diaphragm seal, this also overcomes people's length Take for just sealing (reach dust-proof, fungi-proofing, air-prevention pass through) injectable powder very well by diaphragm seal since phase to make up a prescription and open on nozzle 2 The technology prejudice of mouth end.
Transfusion nozzle 24 is tubulose, and its lower end is connected with substrate 21, and the hollow that substrate 21 is provided with nozzle 24 of infusing is connected Logical liquid through-hole 244;Transfusion nozzle 24 is for being connected with infusion needle;It is additionally provided with transfusion easy-to-draw on the free end of transfusion nozzle 24 Lid 241, the easy-open lid 241 free end phase welding (namely welding) with transfusion nozzle 24 of infusing, transfusion easy-open lid 241 is provided with transfusion Draw ring 2411, can be pulled open the top board of transfusion easy-open lid 241 by transfusion draw ring 2411, be additionally provided with in transfusion easy-open lid 241 Sealing gasket B242 and inner cap B243, pulls open transfusion draw ring 2411 during use, and infusion needle inserts from sealing gasket B242, passes The top of inner cap B243, the whole infusion vessel that then stands upside down gets final product (as shown in figure 14).
Make up a prescription nozzle 23 of aqueous injection is for tubulose, and it is located at transfusion nozzle 24 1 side, its in container body 1 (through transfusion Nozzle 24) preparation (injection) aqueous injection medicine (ampoule bottle institute powder charge thing), aqueous injection make up a prescription nozzle 23 inner chamber and infuse nozzle 24 inner chamber phase Connection;The make up a prescription axis of nozzle 23 of aqueous injection with the horizontal the angle α of 30 ± 5 degree, i.e. α=30 ± 5 °, usually 30 degree, i.e. Aqueous injection make up a prescription nozzle 23 in about 30 degree be inclined and mounted on transfusion nozzle 24 side, when being the most i.e. conducive to making up a prescription medicinal liquid enter Container body 1, is also beneficial to totallyer defeated for medicinal liquid when transfusion, reduces drug residue (as shown in figure 14);Aqueous injection is joined Being additionally provided with aqueous injection easy-open lid 231 on the free end of medicine nozzle 23, aqueous injection easy-open lid 231 is a kind of easy-open lid, and aqueous injection is easy-to-draw Lid 231 makes up a prescription with aqueous injection free end phase welding (namely welding) of nozzle 23, and aqueous injection easy-open lid 231 outer end is provided with aqueous injection and draws Ring 2311, can be easy-to-draw to open aqueous injection by the easy-to-draw parts apart of aqueous injection easy-open lid 231 by aqueous injection draw ring 2311 Lid 231, is additionally provided with sealing gasket A232 and inner cap A233, is pulled open by aqueous injection draw ring 2311 during use in aqueous injection easy-open lid 231, The syringe needle of syringe inserts from sealing gasket A232, through inner cap A233, by aqueous injection infusion of medicine container body 1.
The using method of the present invention and operation principle:
Making of the present invention to be described as a example by powder pin bottle (i.e. cillin bottle 3, lower same), ampoule bottle and infusion bottle (i.e. container body 1, lower same) By method: powder pin easy-open lid 227 is torn, take off puncture needle 25 and protect set 254, cillin bottle 3 in intervention, down press cillin bottle 3, (i.e. demarcation strip 253 snaps at the second location structure, as figs 11-13) puncture needle 25 to lower bayonet socket position;Puncture needle 25 By through the pad (diaphragm seal) of powder pin bottle, injectable powder make up a prescription nozzle 22 cup-shaped bottom equipped with pad 222 and union joint 221 Top be provided with every liquid sheet 228, infusion bottle is connected by puncture needle 25 with powder pin bottle;Shake for several times, allow mixed medicine evenly, mix Medicine enters infusion bottle, completes once to make up a prescription;If needing the most defeated multi-medicament, then need to prepare for the first time according to treatment Powder pin bottle dial down, again join second bottle of injectable powder medicine according to aforesaid operations flow process, as the method can join many bottles of injectable powder Medicine;The aqueous injection medicine prepared the most as required, uses syringe to be extracted out by the aqueous injection medicine in ampoule bottle, then by liquid drugs injection The aqueous injection easy-open lid 231 that agent is made up a prescription on nozzle 23 pulls open, syringe needle pass sealing gasket A232 and inner cap A233, by aqueous injection medicine from Aqueous injection makes up a prescription and injects in infusion bottle in nozzle 23;Transfusion starts, and pulls easy-open lid 241 of infusing on transfusion nozzle 24 to be provided with transfusion and draws Ring 2411, opens transfusion nozzle 24, and infusion needle passes sealing gasket B242 and inner cap B243, again shakes all, the multiple medicine mixed Product enter transfusion bag, and reversal of the natural order of things treatment starts;The make up a prescription axis of nozzle 23 of aqueous injection, with the horizontal the angle α of 30 ± 5 degree, can be protected Noresidue liquid in card infusion bottle, is also convenient for during transfusion again making up a prescription.
The present invention is not limited to above-mentioned concrete structure, as long as have the substrate 21 essentially identical with the present invention, powder pin Make up a prescription nozzle 22, aqueous injection of agent makes up a prescription nozzle 23, transfusion nozzle 24 and the infusion container interface of puncture needle 25 or infusion vessel all falls within this Within the protection domain of invention.

Claims (10)

1. the infusion container interface can the most directly joined multi-pharmaceutics, is characterized in that: it includes substrate (21), injectable powder Make up a prescription nozzle (22), aqueous injection makes up a prescription nozzle (23), transfusion nozzle (24) and puncture needle (25);Substrate (21) is that injectable powder makes up a prescription nozzle (22) With the connecting plate of transfusion nozzle (24), aqueous injection makes up a prescription nozzle (23) and is connected with nozzle (24) of infusing;
The make up a prescription inner chamber of nozzle (22) of injectable powder is injectable powder medicine dispensing cavity, is used for assigning cillin bottle (3), and injectable powder makes up a prescription nozzle (22) dispensing cavity adapts with the head configuration of cillin bottle (3);The make up a prescription bottom of nozzle (22) of injectable powder is provided with union joint (221), union joint (221) is hollow tubular, and the injectable powder nozzle (22) that makes up a prescription is connected through head (221) and is connected with substrate (21) Connecing, substrate (21) is provided with the injectable powder through hole (211) that the hollow with union joint (221) is connected;The top of union joint (221) It is provided with every liquid sheet (228), injectable powder is made up a prescription nozzle (22) and union joint (221) is isolated every liquid sheet (228);Injectable powder makes up a prescription nozzle (22) the other end is opening;The inner chamber of union joint (221) is medicine liquid channel;
Puncture needle (25) be arranged on injectable powder make up a prescription nozzle (22) dispensing cavity in;Injectable powder nozzle (22) upper inside wall position of making up a prescription sets Have the first location structure that the demarcation strip with puncture needle (25) matches, the first location structure puncture needle (25) can be blocked and The most locked position in top portion in injectable powder makes up a prescription nozzle (22);Injectable powder makes up a prescription nozzle (22) inwall position near pad (222) Putting and be additionally provided with the second location structure, puncture needle (25) can be stuck in injectable powder and make up a prescription in nozzle (22) on the lower by the first location structure The position in portion.
The infusion container interface can the most directly joined multi-pharmaceutics the most according to claim 1, is characterized in that: described Puncture needle (25) includes needle tubing and demarcation strip (253);Needle tubing includes winding the needle tube (251) and lower needle tubing (252);Winding the needle tube (251) Being connected with lower needle tubing (252), its interior medicament channel is connected;Demarcation strip (253) is plate shape, and it is arranged on winding the needle tube (251) with lower needle tubing (252) connection;Demarcation strip (253) is provided with more than one clean-out opening (2531);Winding the needle tube (251) head is pointed puncturing head (2511), and the top of puncturing head (2511) is real core, and described puncturing head (2511) is Cone;The side of winding the needle tube (251) is provided with more than one ditch through hole (2512) near puncturing head (2511) place;Winding the needle tube (251) or/and lower needle tubing (252) inwall is circumferentially equipped with two to four reinforcements.
The infusion container interface can the most directly joined multi-pharmaceutics the most according to claim 2, is characterized in that: described First location structure includes raised line on first (226) and first time raised line (223), raised line (226) and first time raised line on first (223) forming draw-in groove (224) between, raised line (226) on first is or/and first time raised line (223) is to be laid in injectable powder to make up a prescription Annular on nozzle (22) inwall raised line or discontinuous multiple projection continuously, demarcation strip (253) can be stuck in the first location structure In;Second location structure includes that the make up a prescription bottom of nozzle (22) of end raised line (225), end raised line (225) and injectable powder is spaced a distance, Distance size adapts with the thickness of demarcation strip (253);End raised line (225) is laid in injectable powder and makes up a prescription on nozzle (22) inwall Annular raised line or scattered multiple projection continuously.
The infusion container interface can the most directly joined multi-pharmaceutics the most according to claim 3, is characterized in that: described Raised line (226) on first is or/and the internal diameter of first time raised line (223) is less than demarcation strip external diameter;The internal diameter score of end raised line (225) Dividing plate (223) external diameter is little;Upper raised line (222), first time raised line (223) and end raised line (225) are for making up a prescription nozzle (22) with injectable powder The structure being molded for integral type.
5. according to infusion container interface multi-pharmaceutics the most directly can joined described in claim 1 or 2 or 3 or 4, its feature Be: described injectable powder make up a prescription nozzle (22) opening on be also associated with powder pin easy-open lid (227), powder pin easy-open lid (227) with The injectable powder nozzle (22) that makes up a prescription is connected by welding.
6. according to infusion container interface multi-pharmaceutics the most directly can joined described in claim 1 or 2 or 3 or 4, its feature It is: described transfusion nozzle (24) is tubulose, and its lower end is connected with substrate (21) that substrate (21) is provided with and nozzle of infusing (24) The liquid through-hole (244) that hollow is connected;It is additionally provided with transfusion easy-open lid (241) on the free end of transfusion nozzle (24), infuses easy-to-draw Cover the free end phase welding of (241) and transfusion nozzle (24);It is additionally provided with sealing gasket B (242) and inner cap B in transfusion easy-open lid (241) (243)。
7. according to infusion container interface multi-pharmaceutics the most directly can joined described in claim 1 or 2 or 3 or 4, its feature It is: the described aqueous injection nozzle (23) that makes up a prescription is tubulose that it is located at transfusion nozzle (24) side, and it is for joining in container body (1) Controlling the water circulation injection drug, aqueous injection make up a prescription nozzle (23) inner chamber with transfusion nozzle (24) intracavity inter-connection;Aqueous injection make up a prescription nozzle (23) from Being additionally provided with aqueous injection easy-open lid (231) by end, the make up a prescription free end of nozzle (23) of aqueous injection easy-open lid (231) and aqueous injection melts mutually Connect.
The infusion container interface can the most directly joined multi-pharmaceutics the most according to claim 7, is characterized in that: described Aqueous injection makes up a prescription the angle α that the axis of nozzle (23) is spent with the horizontal (30) ± (5), i.e. α=(30) ± (5) °;Aqueous injection is easy Sealing gasket A (232) and inner cap A (233) it is additionally provided with in drawing lid (231).
9., according to infusion container interface multi-pharmaceutics the most directly can joined described in Claims 2 or 3 or 4, it is characterized in that: Make up a prescription nozzle (22), aqueous injection of described substrate (21), injectable powder makes up a prescription nozzle (23) and transfusion nozzle (24) is that integral type is molded Structure;Winding the needle tube (251), lower needle tubing (252) and demarcation strip (253) are the structure that integral type is an integrally-molded;Winding the needle tube (251) it is provided with protection set (254);It is the structure that integral type is molded every liquid sheet (228) with union joint (221);Injectable powder The make up a prescription bottom of nozzle (22) is rubber cushion equipped with pad (222), pad (222).
10. the infusion vessel can the most directly joined multi-pharmaceutics, it includes container body (1);It is characterized in that: it also includes Interface (2);Interface (2) is welded on container body (1) by its substrate (21);Container body (1) is transfusion bag or infusion bottle.
CN201610563759.XA 2016-07-18 2016-07-18 The infusion container interface and infusion vessel repeatedly directly matched can be carried out to multi-form Active CN106178155B (en)

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CN113101212A (en) * 2021-04-02 2021-07-13 上海乐纯生物技术有限公司 Aseptic joint and infusion container for preparing injection liquid medicine

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