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CN106176511B - A kind of propolis pore cleanser nose film and its preparation method and application - Google Patents

A kind of propolis pore cleanser nose film and its preparation method and application Download PDF

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Publication number
CN106176511B
CN106176511B CN201610553492.6A CN201610553492A CN106176511B CN 106176511 B CN106176511 B CN 106176511B CN 201610553492 A CN201610553492 A CN 201610553492A CN 106176511 B CN106176511 B CN 106176511B
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extract
propolis
pore
nose film
blackhead
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CN106176511A (en
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冯小虎
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Guangzhou Dzeko Biological Science And Technology Co Ltd
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Guangzhou Dzeko Biological Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/982Reproductive organs; Embryos, Eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to cosmetic technical field, a kind of propolis pore cleanser nose film and its preparation method and application is disclosed.The nose film includes the following components of weight percent: water 50%~60%, polyvinyl alcohol 15%~22%, ethyl alcohol 15%~22%, bentonite 5%~10%, acrylic acid (ester) analog copolymer 1%~3%, propolis extract 0.3%-0.6%, fructus arctii (ARCTIUM LAPPA) extract 0.3%~0.7%, gean (PRUNUS AVIUM) berry extract 0.3%~0.7%, hay flower extract 0.3%~0.7%, egg white extract 0.3%~0.7%, carbon black 2%~5%, triethanolamine 0.1%~0.5%, Phenoxyethanol 0.5%~0.9%, essence 0.1%~0.3%.The present invention extracts natural plant formula, does not stimulate mildly, extracts with root blackhead, and skin zero damages;Grease is improved, moment restrains pore, keeps skin clearly fine and smooth.The present invention can deep clean be damaged pore, solve inflammation;Mild export cutin, bacterium;Injured pore pothole is repaired simultaneously, blackhead is avoided to regenerate.

Description

A kind of propolis pore cleanser nose film and its preparation method and application
Technical field
The present invention relates to cosmetic technical field, specifically a kind of propolis pore cleanser nose film and preparation method thereof and answer With.
Background technique
Blackhead, one kind " bolt " the sample object being mainly made of sebum, cell bits and bacterium, is blocked at hair follicle opening and shape At, in addition dust, dirt and oxidation in air, make a gradually blackening of its ingress of air, form blackhead.Blackhead Appearance be personal skin quality in conjunction with outside environmental elements caused by, the people at any age does not nurse skin well, has out The possibility of existing blackhead.According to famous Derma Clinic investigation show: Ren Qunzhong, 97% adult's nose be easier to it is fuel-displaced, Wherein 90% there are blackhead puzzlements, 68% people's blackhead is than more serious!If except cleaning factor, male and female occurs black The ratio of head is almost identical!The appearance of obvious blackhead, directly affects the beauty of personal image, also as being often accompanied with Cuo The appearance of sore makes skin seem greasy and pain of itching, and people is allowed to feel to feel bad very much!
Currently, people remove the method for blackhead mainly include the following types: (1) pulls out method, by viscous force by blackhead from pore Middle extraction, but this method pulls skin, will lead to pore relaxation and becomes larger, if restrained not in time, blackhead can faster go out Existing, pore can become larger;(2) dissolution method, by smear plus it is stifling allow blackhead emulsification to soften to be easy pore discharge, but this method makes It with more troublesome, needs to spend the long time, being finished skin can be dry;(3) extrusion, will be black by the method for physical impact Head squeezes out, but this method takes a long time, and be easy to cause inflammation, or leaves red seal.
For above situation, need to develop a kind of propolis pore cleanser nose film, can deep clean be damaged pore, solve scorching Disease;Mild export cutin, bacterium;Injured pore pothole is repaired simultaneously, blackhead is avoided to regenerate.
Summary of the invention
In view of the above problems, the object of the present invention is to provide a kind of propolis pore cleanser nose films.
Another object of the present invention is to provide the preparation methods of above-mentioned propolis pore cleanser nose film.
Another object of the present invention is to provide the application of above-mentioned propolis pore cleanser nose film.
The present invention to achieve the above object, takes following technical scheme to be achieved:
A kind of propolis pore cleanser nose film, the following components including weight percent:
One of as a preferred solution of the present invention, which includes the following components of weight percent:
As a preferred solution of the present invention two, which includes the following components of weight percent:
As a preferred solution of the present invention three, which includes the following components of weight percent:
Another object of the present invention is to disclose the preparation method of above-mentioned propolis pore cleanser nose film, comprising the following steps:
(1) polyvinyl alcohol is added in main cooker with the water for accounting for formula total Water mass percent 80%~90%, side stirring While being heated to 85-90 DEG C, when polyvinyl alcohol is completely dissolved, heat preservation starts to cool down after ten minutes;
(2) when being cooled to 45 DEG C, ethyl alcohol is added in main cooker, is vacuumized, after stirring 15 minutes, continue to cool down;
(3) when being cooled to 40 DEG C, acrylic acid (ester) analog copolymer and the water of surplus are uniformly mixed, master is added after filtering In pot, it is separately added into bentonite, propolis extract, fructus arctii (ARCTIUM LAPPA) extract, gean after mixing evenly (PRUNUS AVIUM) berry extract, hay flower extract, egg white extract, carbon black, triethanolamine, Phenoxyethanol and essence, It stirs evenly up to propolis pore cleanser nose film.
Preferably, vacuum degree is -0.05Pa.s in the step (2), and speed of agitator is 60 revs/min.
Propolis pore cleanser nose film produced by the present invention is lotion, bubble-free.
Another object of the present invention is to disclose the application of above-mentioned propolis pore cleanser nose film, comprising the following steps:
(1) with face cleaning product that the area T is clean, covering the area T with hot towel expands pore;
(2) it where taking appropriate propolis pore cleanser nose film to be applied to blackhead at skin, was parched to 10~15 minutes, from top to bottom Nose film is removed, it is clean with clear water.
Preferably, following steps are added before with step (2) after the step (1): is applied at skin where blackhead Blacken the name of head export liquid, 3~after five minutes by its wiped clean.
Preferably, the blackhead export liquid includes the following components of weight percent: water 56.95%, butanediol 19%, hydroxyl Ethyl carbamide 15%, lactic acid 2%, malic acid 2%, propolis extract 0.5%, apricot (PRUNUS ARMENIACA) benevolence extract 0.5%, pawpaw (CHAENOMELES SINENSIS) extract 0.6%, hamamelis (HAMAMELIS VIRGINIANA) Extract 0.6%, peppermint (MENTHA ARVENSIS) extract 0.5%, Sodium Hyaluronate 0.6%, allantoin 0.3%, benzene oxygen Ethyl alcohol 0.7%, rilanit special (PEG-40) 0.5%, essence 0.25%.
Propolis is a kind of extremely rare natural resources, is known as the title of " purple gold ", chemically at subangle from the point of view of, bee Glue chemical component is more complicated, and with trees and the season difference of acquisition, product is also variant.Its main component has flavones Class, terpenes, organic acid, armaticity aldehyde, alcohols, lipid, a variety of amino acid, enzyme, vitamin, mineral money etc..There is research table Bright: take propolis not only can be purified pigmentation, be improved microcirculation with toxin-expelling and face nourishing, moreover it is possible to be prevented lipid peroxidation, be reduced color Plain calm, antibacterial anti-inflammatory excludes virus;Anti-oxidant, enhancement of SOD activity prevents lipid peroxidation;Reinforced immunological improves self-healing Power.Blood vessel is purified, blood vessel is softened, improves microcirculation.
Multivitamin and minerals of the fructus arctii containing needed by human body such as synanthrin, cellulose, protein, calcium, phosphorus, iron, wherein Carotene carotene content is 150 times higher than carrot, and the content of protein and calcium is first of tubers.Radix bardanae contains synanthrin and volatilization Oil, arctic acid, a variety of polyphenol substances and aldehydes, and it is rich in cellulose and amino acid, antibacterial action, anti-aging effects are anti-oxidant Effect.
Cherry is 35 times of lemon containing VC, is 17 times of strawberry, is that guava is 11 times high, is known as " king of vitamin ", together Shi Hanyou VitAVitE, citrin, vitamin B complex, carotenoid, anthocyanidin, flavonoids, protein, iron, calcium Deng, be a kind of compound anti-oxidation object, have potent inoxidizability.15. hay flower extract: anti-inflammatory, dissolution cutin effect.Have It is apparent to inhibit melanin formation, antiallergy, antibacterial, antibacterial, anti-oxidant, anti-fading, anti-acne and other effects.
Egg white can not only make whiteness of skin, and can make skin delicacy, removal dead skin.This is because it contain it is abundant Protein and a small amount of acetic acid, the lubricating action of skin can be enhanced in protein, and acetic acid can protect the subacidity of skin, to prevent Bacterium infection.In addition, egg, which is checked up and return, has the function of clearing heat and detoxicating and enhancing skin immune function controlling.It releives skin, moment supplement Skin moisture, promoted skin moisturizing ability, strengthen moisture-retaining capacity make skin reproduce gloss with it is beautiful, keep the year light-water of skin It is tender.
Compared with prior art, beneficial effects of the present invention are as follows:
The present invention extracts natural plant formula, does not stimulate mildly, extracts with root blackhead, and skin zero damages;Improve grease, wink Between restrain pore, keep skin clearly fine and smooth.
Natural plant formula of the invention can improve grease, by oil-control, convergence, mitigate pore expansion pressure, repair U-shaped pore, the fine and smooth soft skin of remodeling.
Natural plant formula of the invention is able to ascend skin phylactic power defensive power.Moment reaches pore root, and 3D hauling type is compact Repair pore cell elasticity.
Natural plant formula of the invention, can mild pore cleanser, penetrate into hair follicle root, activate and to loosen pore deep layer black Head and hoary hair, effect are more accurate.
The present invention can deep clean be damaged pore, solve inflammation;Mild export cutin, bacterium;Injured hair is repaired simultaneously Hole pothole, avoids blackhead from regenerating.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is further illustrated.
Embodiment 1
Score meter by weight: water 57.45%, polyvinyl alcohol 19%, ethyl alcohol 15%, bentonite 9%, acrylic acid (ester) class Copolymer 2%, propolis extract 0.5%, fructus arctii (ARCTIUM LAPPA) extract 0.5%, gean (PRUNUS AVIUM) berry extract 0.6%, showy flowers of herbaceous plants extract 0.6%, egg white extract 0.5%, CI 77,266 3.00%, triethanolamine 0.3%, Phenoxyethanol 0.7%, essence 0.25%.It is prepared by the specification of 100ml.
According to above-mentioned formula, prepared according to following steps:
(1) water of polyvinyl alcohol, Zhan Peifang total Water mass percent 80%~90% is added in main cooker, while stirring 85~90 DEG C are heated to, until polyvinyl alcohol is completely dissolved, heat preservation starts to cool down after ten minutes;
(2) when being cooled to 45 DEG C, ethyl alcohol is added in main cooker, (vacuum degree is -0.05Pa.s) is vacuumized, stirs 15 points After clock (revolving speed is 60 revs/min), continue to cool down;
(3) when being cooled to 40 DEG C, acrylic acid (ester) analog copolymer and the water of surplus are uniformly mixed, master is added after filtering In pot, it is separately added into bentonite, propolis extract, fructus arctii (ARCTIUM LAPPA) extract, gean after mixing evenly (PRUNUS AVIUM) berry extract, hay flower extract, egg white extract, CI 77266, triethanolamine, Phenoxyethanol, perfume (or spice) Essence stirs evenly, and keeps lotion bubble-free, this product can be obtained.
In step (3), because acrylic acid (ester) analog copolymer can be agglomerated into film during storage forms few particle, because This, adds in main cooker after filtering.Filtering uses filter-cloth filtering.
Embodiment 2
Score meter by weight: water 55.25%, polyvinyl alcohol 20%, ethyl alcohol 15%, bentonite 8%, acrylic acid (ester) class are total Polymers 2%, propolis extract 0.8%, fructus arctii (ARCTIUM LAPPA) extract 0.7%, gean (PRUNUS AVIUM) berry extract 0.6%, hay flower extract 1%, egg white extract 0.7%, CI 77,266 3.00%, triethanolamine 0.4%, Phenoxyethanol 0.7%, essence 0.25%.It is prepared by the specification of 100ml.
Preparation method such as embodiment 1
Embodiment 3
Score meter by weight: water 64.15%, polyvinyl alcohol 15%, ethyl alcohol 13%, bentonite 7%, acrylic acid (ester) class are total Polymers 2%, propolis extract 0.3%, fructus arctii (ARCTIUM LAPPA) extract 0.4%, gean (PRUNUS AVIUM) berry extract 0.5%, hay flower extract 0.5%, egg white extract 0.4%, CI 77,266 3.00%, three ethyl alcohol Amine 0.2%, Phenoxyethanol 0.5%, essence 0.25%.It is prepared by the specification of 100ml.
Preparation method such as embodiment 1
Embodiment 4
The present embodiment discloses the application method of product made from Examples 1 to 3, specifically includes the following steps:
(1) with face cleaning product that the area T is clean, covering the area T with hot towel expands pore;
(2) it where taking appropriate propolis pore cleanser nose film to be applied to blackhead at skin, was parched to 10~15 minutes, from top to bottom Nose film is removed, it is clean with clear water.
Embodiment 5
Following steps are added before with step (2) after the step of embodiment 4 (1): being blackened the name of applying at skin where blackhead Head export liquid, 3~after five minutes by its wiped clean.Other are the same as embodiment 4.
Blackhead export liquid include weight percent following components: water 56.95%, butanediol 19%, ethoxy urea 15%, Lactic acid 2%, malic acid 2%, propolis extract 0.5%, apricot (PRUNUS ARMENIACA) benevolence extract 0.5%, pawpaw (CHAENOMELES SINENSIS) extract 0.6%, hamamelis (HAMAMELIS VIRGINIANA) extract 0.6%, peppermint (MENTHA ARVENSIS) extract 0.5%, Sodium Hyaluronate 0.6%, allantoin 0.3%, Phenoxyethanol 0.7%, rilanit special (PEG-40) 0.5%, essence 0.25%.
The present embodiment 5 compared with Example 4, pore cleanser better effect.
Comparative example 1
Propolis extract, fructus arctii (ARCTIUM LAPPA) extract are not added in formula, the other the same as in Example 1 is made pair According to product 1.
Comparative example 2
Gean (PRUNUS AVIUM) berry extract, hay flower extract, egg white extract are not added in formula, Reference substance 2 is made in the other the same as in Example 1.
Comparative example 3
Ethyl alcohol, triethanolamine are not added in formula, reference substance 3 is made in the other the same as in Example 1.
For above-described embodiment 1~3, comparative example 1~3 carries out Product Safety evaluation respectively, and (human skin patch is real Test), specific as follows:
One, tested material: propolis pore cleanser nose film (Examples 1 to 3) produced by the present invention, reference substance (comparative example 1~3).
Two, tested crowd
Number: 30 people
Age: between 20~50 years old
Gender: 23 people of female, male 7 people
Health status: subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Three, patch method: qualified spot tester is selected, with closed patch experiment method, by 0.020ml~0.025ml Tested material is dripped in spot tester, is covered on subject back with external application special adhesive tape, tested material is removed after 24 hours, is removed respectively Observation dermoreaction in 0.5,6,12,24,48 hour afterwards, records it according to dermoreaction grade scale in " cosmetics health specification " As a result.
Four, experimental result
Human skin patch test result is shown: propolis pore cleanser nose film obtained is (real through the invention by 30 subjects Apply example 1~3), reference substance (comparative example 1~3) patch test, in observation dermoreaction in 0.5,6,12,24,48 hour, wherein 0 There is skin adverse reaction, it is safe to illustrate that propolis pore cleanser nose film produced by the present invention uses.
For above-described embodiment 1~3, comparative example 1~3 carries out testing using result respectively, specific as follows:
One, tested material: propolis pore cleanser nose film (Examples 1 to 3) produced by the present invention, reference substance (comparative example 1~3).
Two, tested crowd
Tested crowd
Gender number: female, 50 people
Age: between 20~40 years old
Health status: subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Test method: after subject cleans face, respectively by propolis de-black prepared by Examples 1 to 3, comparative example 1~3 Using effect is observed and experienced to head nose film with the area T is smeared.
Three, test assessment result is as shown in the following table 1~3:
1 embodiment 1 of table prepares (8 days) the feedback conclusive tables on probation of product
2 embodiment 2~3 of table prepares (7 days) the feedback conclusive tables on probation of product
3 comparative example 1~3 of table prepares (7 days) the feedback conclusive tables on probation of product
Tester indicates that embodiment 1 prepares product and is better than product prepared by embodiment 2,3 in all respects, and Better than product prepared by comparative example 1~3, penetrating power is extremely strong, draws blackhead and tough stains in pore, fast convergence Pore, the limited low and deep coarse skin quality of improvement improve fat secretion, reduce small pox and generate and repair impaired skin.User simultaneously Questionnaire in non-someone have allergic phenomena.
For above-described embodiment 1~3, commercially available similar propolis pore cleanser nose film carries out testing using result respectively, specifically such as Under:
One, tested material: propolis pore cleanser nose film (Examples 1 to 3) produced by the present invention, commercially available similar propolis pore cleanser nose Film.
Two, tested crowd
Gender number: female, 50 people
Age: between 20~40 years old
Health status: subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.
Test method: after subject cleans face, respectively by Examples 1 to 3 propolis pore cleanser nose film, commercially available similar propolis Pore cleanser nose film smears the area T, observes and experience using effect.
Three, test assessment result is as shown in table 4 below:
The comparison statistical table of 4 pore cleanser ability of table
Tester indicates, in terms of propolis pore cleanser ability, embodiment 1 prepare product be better than in all respects embodiment 2, Product prepared by 3, is superior to commercially available similar propolis pore cleanser nose film, and tester prepares product to embodiment 1 and especially approves.
It is provided for the embodiments of the invention technical solution above to be described in detail, specific case used herein The principle and embodiment of the embodiment of the present invention are expounded, the explanation of above embodiments is only applicable to help to understand this The principle of inventive embodiments;At the same time, for those skilled in the art, according to an embodiment of the present invention, in specific embodiment party There will be changes in formula and application range, in conclusion the contents of this specification are not to be construed as limiting the invention.

Claims (3)

1. a kind of propolis pore cleanser nose film, which is characterized in that the following components including weight percent:
The application of the propolis pore cleanser nose film, comprising the following steps:
(1) with face cleaning product that the area T is clean, covering the area T with hot towel expands pore;
(2) liquid is exported smearing blackhead where blackhead at skin, 3~after five minutes by its wiped clean;
(3) it where taking appropriate propolis pore cleanser nose film to be applied to blackhead at skin, parched to 10~15 minutes, removes from top to bottom Nose film, it is clean with clear water;
Blackhead export liquid includes the following components of weight percent: water 56.95%, butanediol 19%, ethoxy urea 15%, Lactic acid 2%, malic acid 2%, propolis extract 0.5%, apricot (PRUNUS ARMENIACA) benevolence extract 0.5%, pawpaw (CHAENOMELES SINENSIS) extract 0.6%, hamamelis (HAMAMELIS VIRGINIANA) extract 0.6%, peppermint (MENTHA ARVENSIS) extract 0.5%, Sodium Hyaluronate 0.6%, allantoin 0.3%, Phenoxyethanol 0.7%, rilanit special (PEG-40) 0.5%, essence 0.25%.
2. the preparation method of propolis pore cleanser nose film as described in claim 1, which comprises the following steps:
(1) by polyvinyl alcohol and account for formula total Water mass percent 80%~90% water be added main cooker in, while stirring plus Heat is to 85~90 DEG C, and when polyvinyl alcohol is completely dissolved, heat preservation starts to cool down after ten minutes;
(2) when being cooled to 45 DEG C, ethyl alcohol is added in main cooker, is vacuumized, after stirring 15 minutes, continue to cool down;
(3) when being cooled to 40 DEG C, acrylic acid (ester) analog copolymer and the water of surplus is uniformly mixed, main cooker is added after filtering In, it is separately added into bentonite, propolis extract, fructus arctii (ARCTIUM LAPPA) extract, gean after mixing evenly (PRUNUS AVIUM) berry extract, hay flower extract, egg white extract, carbon black, triethanolamine, Phenoxyethanol and essence, It stirs evenly up to propolis pore cleanser nose film.
3. the preparation method of propolis pore cleanser nose film according to claim 2, which is characterized in that true in the step (2) Reciprocal of duty cycle is -0.05Pa.s, and speed of agitator is 60 revs/min.
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CN107823088A (en) * 2017-11-30 2018-03-23 广州市梦采生物科技有限公司 A kind of make-up composition of quick pore cleanser and preparation method thereof
CN110585102B (en) * 2019-10-30 2022-07-15 广州留今科学研究有限公司 Blackhead-derived plant composition, blackhead-derived liquid and preparation method
CN113368021A (en) * 2021-06-09 2021-09-10 谭洪荣 Liquid nasal membrane for removing blackheads and preparation method and application thereof
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黑头导出液能去黑头吗 教你黑头导出液的用法;佚名;《美颜网,网址:http://www.meiyanw.com/meifu/201208/3624.html》;20120830;第1页文章正文 *
鼻尖黑头怎么去除;佚名;《新浪博客,网址:http://blog.sina.com.cn/u/3978753134》;20140509;第1-3页博客正文 *

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