CN105343450A

CN105343450A - Emulsion for treating keratosis pilaris and preparation method of emulsion

Info

Publication number: CN105343450A
Application number: CN201510726494.6A
Authority: CN
Inventors: 孙淑萍; 李胜利; 孟宏武; 宋奥琪; 鲍堃; 王雅兰; 叶萍
Original assignee: Wannan Medical College
Current assignee: Wannan Medical College
Priority date: 2015-10-28
Filing date: 2015-10-28
Publication date: 2016-02-24

Abstract

The invention discloses an emulsion for treating keratosis pilaris and a preparation method of the emulsion. The emulsion consists of the following materials: aloe oil, avocado oil, chamomile, Arabic gum, tragacanth, sodium alginate, a centella asiatica extracting solution, a liquorice extracting solution, a loofah extracting solution, a cortex moutan extracting solution, an angelica sinensis extracting solution, tretinoin, vitamin A, urine, salicylic acid, glycerol, an ethylparaben alcohol solution and distilled water. Most raw materials in the finished product are extracted from traditional Chinese medicinal raw materials; the emulsion, which is subject to a method combining natural ingredient extracts and plant essential oil, has the characteristics of being gentle in nature and high in safety, and the emulsion is low in irritation to skin, free from toxic and side effects and is suitable for people of various sensitive skin. The emulsion, on the basis of a synergistic effect fully developed from the various traditional Chinese medicines which are combined in use, can be used for effectively improving the symptoms of the keratosis pilaris. In addition, the emulsion also has effects of moisturizing and nourishing, and promoting absorption, and the emulsion is capable of keeping skin tight, tender and elastic.

Description

A kind of emulsion for the treatment of dyskeratosis follicularis and preparation method thereof

Technical field

The present invention relates to a kind of emulsion, particularly a kind of emulsion for the treatment of dyskeratosis follicularis and preparation method thereof, belong to face beautifying medicine field.

Background technology

Dyskeratosis follicularis, keratosis pilaris, be commonly called as Corium Gallus domesticus skin, is the genetic dermatosis of the keratinization process exception that a kind of autosomal dominant inheritance, AD causes.Someone thinks that Vitamin A Metabolism obstacle and sun exposure are important paathogenic factors.Have the people of this body constitution, parafollicular cutin can thicken, and causes follicular orifice to be blocked by blocked up cutin, forms the small embossment of a grain.Show as xerosis cutis, pimple, coarse, fine hair roll up in hair follicle, affect very much attractive in appearance.

It is then fast that dyskeratosis follicularis can allow people want to remove, but squeeze with hands, grab, scratch, and can make the tissue edema around pore, such pore opening becomes less, more easily blocks, and can produce acne, folliculitis; If scratched, more inflammation and pigementation can be caused.So must not go to grab, go to scratch.So not only skin is easily injured, also easily by hair follicle inflammation, can cause cicatrix and pigementation by chafe.Painting retinoic acid or carry out fruit acid and change skin under specialist instructs, can allow skin improve at several days.But this is " emergent method " just, cures the symptoms, not the disease, if often process like this, the barrier function of skin also can be made to become more weak, make skin drier, more responsive.

Chinese medicine theory is thought, dyskeratosis follicularis is many by retention of damp-heat in the interior, outward by pathogenic heat, and then stifling lung system, pent up skin and send out.The strongly fragrant heat-transformation of a specified duration of evil poison, the corruption of intenseness of heat meat then becomes pus, and septicopyemia is fled, mutually through, sends out as folliculitis.Or because of ferritic weakness, weakened defensive QI, diseases caused by exogenous pathogenic factor pyretic toxicity; Or because of skin unclean, attacked by pathogenic wind toxic, fight outside wind knot and cause.According to the pathology congenital defect of dyskeratosis follicularis, blood-deficiency and wind-dry, so that skin battalion defends and becomes estranged and send out, adopting has the oral medicinal herb of Glycerin, active dissipating blood stasis, wind dispelling itching-relieving efficacies and outer wiping to treat this disease, curative effect is very remarkable, so now a lot of patients can take the traditional Chinese medical science, treatment by Chinese herbs dyskeratosis follicularis.

Find after deliberation, the A that is deficient in vitamin can cause the drying of general, and drying will aggravate the symptom of follicular keratosis.Salicylic acid, originally as fat-soluble, just along hair follicle opening, can arrive keratinization position along skin oil and fat, and then dissolve cutin, improve symptom.Carbamide, tretinoin can horny layer softenings, moisturizing skin.The raw materials such as Herba Centellae, Radix Glycyrrhizae, Radix Angelicae Sinensis, natural Flos Matricariae chamomillae, Fructus Luffae are the effective for the treatment of folliculitis and the composition of safety, the stimulation of pharmaceutical through skin can be reduced, antimicrobial antiphlogistic, antipyretic and itching-stopping, strengthen body immunity, reduce anaphylaxis, improve the super quick skin such as dry moss eczema, produce effect of purifying skin simultaneously, also the improvement of effective and safe ground even can eliminate folliculitis.If add corresponding both effectiveness composition in emulsion, just can while cutin be dissolved in mitigation, Glycerin, nutrition skin, makes skin obtain abundant moisturizing, and dyskeratosis follicularis problem just can be made progressively to improve.

Summary of the invention

In order to solve problems of the prior art, the invention provides a kind of emulsion for the treatment of dyskeratosis follicularis, and adopting the preparation method of science, can effectively improve and treat dyskeratosis follicularis.

To achieve these goals, the technical scheme that the present invention takes is:

Treat an emulsion for dyskeratosis follicularis, include following material:

Described aloe, American Avocado Tree oil, arabic gum, tragakanta, sodium alginate, tretinoin, vitamin A, carbamide, salicylic acid, glycerol is commercially available.

2% described ethyl hydroxybenzoate alcoholic solution ethyl hydroxybenzoate and 75% (volume ratio) alcoholic solution are 2% formulated by volume.

Treat a preparation method for the emulsion of dyskeratosis follicularis, comprise the following steps:

Step one: take salicylic acid, is dissolved in 1-10ml distilled water, as solution 1, stand-by;

Step 2: take tretinoin, vitamin A, carbamide, is dissolved in 5-15ml distilled water, as solution 2, stand-by;

Step 3: take sodium alginate, is scattered in 30-60ml distilled water, stirring and dissolving, as gel solution 3, stand-by;

Step 4: measure aloe, American Avocado Tree oil, Flos Matricariae chamomillae soaks oil, is placed in mortar, then takes arabic gum, tragakanta, be placed in mortar, add 2-10ml distilled water, after grinding evenly, obtains colostrum 1;

Step 5: add solution 1, solution 2, gel solution 3 and 2-10ml distilled water in step 4 colostrum 1, grinding evenly, obtains substrate 1;

Step 6: add Herba Centellae extracting solution in step 5 substrate 1, Radix Glycyrrhizae extract, Fructus Luffae extracting solution, Cortex Moutan extracting solution, Radix Angelicae Sinensis extracting solution, glycerol, and 2% ethyl hydroxybenzoate alcoholic solution, be uniformly mixed and use high-speed tissue mashing machine's mix homogeneously afterwards, the emulsion of dyskeratosis follicularis must be treated.

Described Flos Matricariae chamomillae soaks oil to be prepared by the following method:

Take natural Flos Matricariae chamomillae 20-40g, after soaking 1-5 days with the olive oil of 6-15 times of Flos Matricariae chamomillae weight, put in ultrasonic extractor, be heated to 30-60 DEG C, ultrasonic extraction 0.5-1.5h, power is 240W, frequency is 40kHz, filters and obtains Flos Matricariae chamomillae soak oil with double gauze.

Described Radix Glycyrrhizae extract is prepared by the following method:

Take Radix Glycyrrhizae 30-50g, be ground into coarse powder, add the water soaking 0.25-0.80h of 10-15 times of Radix Glycyrrhizae weight, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 1; In filtering residue, add the water of 8-10 times of filtering residue weight, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 2; In filtering residue, add the water of 6-8 times of filtering residue weight again, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 3; Filtrate 1, filtrate 2, filtrate 3 are merged, the 5-8 being concentrated into Radix Glycyrrhizae weight under temperature is 80-100 DEG C of condition doubly, obtains Radix Glycyrrhizae extract.

Described Herba Centellae extracting solution is prepared by the following method:

Take Herba Centellae 20-50g, add the water soaking 0.25-0.80h of 15-20 times of Herba Centellae weight, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 1; In filtering residue, add the water of 10-15 times of filtering residue weight, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 2; In filtering residue, add the water of 10-12 times of filtering residue weight again, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 3; Filtrate 1, filtrate 2, filtrate 3 are merged, the 5-8 being concentrated into Herba Centellae weight under temperature is 80-100 DEG C of condition doubly, obtains Herba Centellae extracting solution.

Described Fructus Luffae extracting solution is prepared by the following method:

Take fresh Fructus Luffae 100-200g, be cut into lamellar, add the water of 10-15 times of Fructus Luffae weight, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 1; In filtering residue, add the water of 10-15 times of filtering residue weight, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 2; In filtering residue, add the water of 10-12 times of filtering residue weight again, be heated to 90-100 DEG C, decoct and extract 0.5-1.5h, filter to get filtrate 3; Filtrate 1, filtrate 2, filtrate 3 are merged, the 5-8 being concentrated into Fructus Luffae weight under temperature is 80-100 DEG C of condition doubly, obtains Fructus Luffae extracting solution.

Described Radix Angelicae Sinensis extracting solution is prepared by the following method:

Take Radix Angelicae Sinensis 40-50g, be ground into coarse powder, add 75% (volume ratio) alcoholic solution of 10-16 times of Radix Angelicae Sinensis weight, soak 0.25-0.80h, reflux, extract, 0.5-1.5h, obtain filtrate 1 by 3 layers of filtered through gauze; In filtering residue, add 75% alcoholic solution of 10-15 times of filtering residue weight, reflux, extract, 0.5-1.5h, obtain filtrate 2 by 3 layers of filtered through gauze; In filtering residue, add 75% alcoholic solution of 8-10 times of filtering residue weight again, reflux, extract, 0.5-1.5h, obtain filtrate 3 by 3 layers of filtered through gauze; Filtrate 1, filtrate 2, filtrate 3 are merged, temperature be 40-50 DEG C, vacuum is evaporated to the 5-8 of Radix Angelicae Sinensis weight doubly under being 0.05-0.08Pa condition, obtain Radix Angelicae Sinensis extracting solution.

Described Cortex Moutan extracting solution is prepared by the following method:

Take Cortex Moutan 30-50g, be ground into coarse powder, add 70% (volume ratio) alcoholic solution of 10-16 times of Cortex Moutan weight, soak 0.25-0.80h, reflux, extract, 0.5-1.5h, obtain filtrate 1 by 3 layers of filtered through gauze; In filtering residue, add 70% alcoholic solution of 10-15 times of filtering residue weight, reflux, extract, 0.5-1.5h, obtain filtrate 2 by 3 layers of filtered through gauze; In filtering residue, add 70% alcoholic solution of 8-10 times of filtering residue weight again, reflux, extract, 0.5-1.5h, obtain filtrate 3 by 3 layers of filtered through gauze; Filtrate 1, filtrate 2, filtrate 3 are merged, temperature be 40-50 DEG C, vacuum is evaporated to the 5-8 of Cortex Moutan weight doubly under being 0.05-0.08Pa condition, obtain Cortex Moutan extracting solution.

Aloe, containing natural colloidality material, water conservation lignin, has strong permeate substance, nutrient can be helped to penetrate into skin Fructus Gleditsia.It not only has powerful clean, antimicrbial power effect, also has moist moisturizing, whitening and speckle dispelling, defying age, the directly cosmetic result such as hypo-allergenic.β-carotene contained in aloe can improve the function of detoxification of body, and be conducive to carcinogen fast deactivation, also have inhibitory action to the activation of precarcinogen, it can also be eliminated free radical and stop the generation of free radical, delaying skin aging.Aloe is applicable to various skin quality, especially to oily skin and easily inflammation skin is very helpful.Wherein contained pure oiliness Aloe lime set, the skin burning, abrade and lose after Exposure to Sunlight moisture content more the moistening and nutrient of deep layer, and repair impaired cell tissue rapidly, impel cell regeneration, and your skin is got well.

American Avocado Tree oil contains abundant vitamin B2, permeate well, can infiltrate skin epidermis, has extraordinary moisturizing effect to dry skin, gives skin and moistens fully, and skin and muscles are fair in order, careful glossy.Be applicable to dry, aging and problem skin.

Flos Matricariae chamomillae soaks oil and has aging resistance, moist, moisturizing, releive, calm skin restrain effect of pore; Add have refrigerant, help the effect of skin tissue regeneration, can also play well loosen, the effect of skin of releiving, Gan Xian can be helped improve, the super quick skin such as eczema, while treatment folliculitis, play the effect of purifying skin.

Herba Centellae extracting solution can compact epidermis and corium coupling part, and skin is limbered up, and promotes skin collagen regeneration, strengthen cell based bottom cell viability, keep elasticity of skin and consolidation, thus contribute to solving cutis laxa phenomenon, make skin smooth flexible.While promoting epidermis to be connected with close between corium, the increase of adipose cell can be suppressed again, prevent hydroderma, fat phenomenon.It has antioxidation, can suppress free radical activity, regulates skin immunity, desalination melanin, and increase skin water conservation degree, activation upgrades skin cell.

Radix Glycyrrhizae extract, containing glycyrrhizic acid iridium--glycyrrhizic acid and glycyrrhetate, has the effect of antiinflammatory, antiallergic action, can also suppress capillary permeability.Radix Glycyrrhizae has the sample effect of salt hydrocortisone and the effect of glucocorticosteroid sterol sample.Licoflavone also has restraint of tyrosinase activity, removes oxygen order by base, and its oxidation resistance and vitamin E are relatively.

Fructus Luffae extracting solution contains carbohydrate, plant mucilage, vitamin and mineral etc., can maintain horny layer normal moisture content, and slow down dehydration and prolongation hydration; Can also enhance metabolism, soft absorption is useless cutin always, removes deep layer dirt, check melanin Hemapoiesis, effectively improves coarse skin wrinkly, makes skin properties become soft and moist glossy.In addition Fructus Luffae extracting solution also has promoting blood circulation to remove obstruction in the collateral, the effect of heat clearing away skin moistening, often uses the blackhead, acne etc. that effectively can dispel skin of face.Sucus Luffae is sweet, gentle, and scalable face sebum secretion, has clearly to skin of face, convergence, calm, the function of balance.

Cortex Moutan extracting solution has the effect of anti-inflammatory, antibacterial, effectively can resist inflammation, kill bacteria.Can immunity of organism be increased, the immune system phylactic power defensive power of health is provided, to a certain degree avoid health to be subject to the infection of virus.

Radix Angelicae Sinensis extracting solution can expand peripheral blood vessel, reduces vascular resistance, increases circulating liquid measure etc.Tryrosinase in human body can produce the melanin causing freckle, black speck, senile plaque, and its activity is higher, then the appearance of senile plaque more early, and quantity is also more.The function of the aqueous solution restraint of tyrosinase activity of Radix Angelicae Sinensis is very strong, thus can the formation of check melanin, produces effects well, have defying age and beautification function to pigmented dermatosis such as treatment chloasma, freckle etc.Radix Angelicae Sinensis is added in cosmetic cream, QUBAN SHUANG, in the hope of skin nutrition, prevent pachylosis, prevent and treat the effects such as acne, chloasma, freckle.

Glycerol is wetting agent, penetration enhancer, can effectively promote the Transdermal absorption of the both effectiveness composition in prescription.

Beneficial effect of the present invention is: this product Raw is most to be obtained for Chinese crude drug extracts, adopt the method that natural component extract and botanical oil combine, have the advantages that character gentleness, safety are high, little to the zest of skin, nontoxic, have no side effect, be applicable to the crowd of all kinds of responsive skin quality.Various Chinese medicine with the use of, give full play to its collaborative compatibility effect, can effectively improve follicular keratosis symptom.Also have moisturizing and nourishing, the effect easily absorbed, skin is compacted, and water is tender, high resilience.

Detailed description of the invention

Embodiment 1

Treat an emulsion for dyskeratosis follicularis, include following material: aloe 2ml, American Avocado Tree oil 1ml, Flos Matricariae chamomillae soaks oily 2ml, arabic gum 1.5g, tragakanta 0.5g, sodium alginate 0.4g, Herba Centellae extracting solution 2ml, Radix Glycyrrhizae extract 2ml, Fructus Luffae extracting solution 2ml, Cortex Moutan extracting solution 2ml, Radix Angelicae Sinensis extracting solution 2ml, tretinoin 0.09g, vitamin A 0.1g, carbamide 0.5g, salicylic acid 0.6g, glycerol 4ml, 2% ethyl hydroxybenzoate alcoholic solution 1ml, distilled water 81ml.

Step one: take salicylic acid, is dissolved in 3ml distilled water, as solution 1, stand-by;

Step 2: take tretinoin, vitamin A, carbamide, is dissolved in 10ml distilled water, as solution 2, stand-by;

Step 3: take sodium alginate, is scattered in 50ml distilled water, stirring and dissolving, as gel solution 3, stand-by;

Step 4: measure aloe, American Avocado Tree oil, Flos Matricariae chamomillae soaks oil, is placed in mortar, then takes arabic gum, tragakanta, be placed in mortar, add 8ml distilled water, after grinding evenly, obtains colostrum 1;

Step 5: add solution 1, solution 2, gel solution 3 and 10ml distilled water in step 4 colostrum 1, grinding evenly, obtains substrate 1;

Embodiment 2

Treat an emulsion for dyskeratosis follicularis, include following material: aloe 2ml, American Avocado Tree oil 2ml, Flos Matricariae chamomillae soaks oily 2ml, arabic gum 2g, tragakanta 1g, sodium alginate 0.3g, Herba Centellae extracting solution 2ml, Radix Glycyrrhizae extract 3ml, Fructus Luffae extracting solution 3ml, Cortex Moutan extracting solution 2ml, Radix Angelicae Sinensis extracting solution 2ml, tretinoin 0.05g, vitamin A 0.1g, carbamide 0.5g, salicylic acid 0.5g, glycerol 4ml, 2% ethyl hydroxybenzoate alcoholic solution 1ml, distilled water 66ml.

Step 2: take tretinoin, vitamin A, carbamide, is dissolved in 5ml distilled water, as solution 2, stand-by;

Step 3: take sodium alginate, is scattered in 40ml distilled water, stirring and dissolving, as gel solution 3, stand-by;

Embodiment 3

Treat an emulsion for dyskeratosis follicularis, include following material: aloe 2ml, American Avocado Tree oil 2ml, Flos Matricariae chamomillae soaks oily 2ml, arabic gum 2g, tragakanta 1g, sodium alginate 0.5g, Herba Centellae extracting solution 2ml, Radix Glycyrrhizae extract 2ml, Fructus Luffae extracting solution 2ml, Cortex Moutan extracting solution 2ml, Radix Angelicae Sinensis extracting solution 2ml, tretinoin 0.1g, vitamin A 0.1g, carbamide 0.5g, salicylic acid 0.7g, glycerol 4ml, 2% ethyl hydroxybenzoate alcoholic solution 1ml, distilled water 81ml.

Embodiment 4

Treat an emulsion for dyskeratosis follicularis, include following material: aloe 5ml, American Avocado Tree oil 5ml, Flos Matricariae chamomillae soaks oily 5ml, arabic gum 2g, tragakanta 1g, sodium alginate 0.5g, Herba Centellae extracting solution 5ml, Radix Glycyrrhizae extract 5ml, Fructus Luffae extracting solution 5ml, Cortex Moutan extracting solution 5ml, Radix Angelicae Sinensis extracting solution 5ml, tretinoin 0.15g, vitamin A 0.15g, carbamide 1.0g, salicylic acid 1.0g, glycerol 7ml, 2% ethyl hydroxybenzoate alcoholic solution 2ml, distilled water 105ml.

Step one: take salicylic acid, is dissolved in 10ml distilled water, as solution 1, stand-by;

Step 2: take tretinoin, vitamin A, carbamide, is dissolved in 15ml distilled water, as solution 2, stand-by;

Step 3: take sodium alginate, is scattered in 60ml distilled water, stirring and dissolving, as gel solution 3, stand-by;

Step 4: measure aloe, American Avocado Tree oil, Flos Matricariae chamomillae soaks oil, is placed in mortar, then takes arabic gum, tragakanta, be placed in mortar, add 10ml distilled water, after grinding evenly, obtains colostrum 1;

The physical and chemical index of embodiment 1,2,3,4 is as follows:

1, quality composition test

Be extruded on the palm of the hand by emulsion prepared by embodiment 1,2,3,4, fine and smooth through observing this emulsion quality softness, emulsion components is many and fine and smooth.

2, pH value inspection

Dip the emulsion of a small amount of embodiment 1,2,3,4 preparation with pH reagent paper, recording pH is 6-7.

3, caloric test

Emulsion prepared by embodiment 1,2,3,4 is packaged in transparence cosmetic bottle, within one week, observes without lamination in the refrigerator cold-storage of 4 DEG C.In the calorstat of 55 DEG C, preserve 24h, emulsion is without layering, the phenomenon such as spoiled.

4, centrifugal test

Emulsion prepared by embodiment 1,2,3,4 be packaged in tool plug test tube, 3000r/min centrifugal treating 20min, without lamination.

5, irritation test, anaphylaxis experiment

White mice back cuts off hair, emulsion prepared by embodiment 1,2,3,4 is applied in respectively and cuts plucked position, and after spending 30 minutes, and no painting position does not compare, and result does not have zest and anaphylaxis.

Choose 15-65 year volunteer 65 people, emulsion 1 gram prepared by Example 1,2,3,4 is applied in volunteer's gesture and facial expression, observes after spending 30 minutes, does not all occur rubescent, dermexanthesis, foaming phenomena.

6, room temperature places experiment

By embodiment 1,2,3,4 made emulsions are placed in bottle for cosmetics, room temperature leaves standstill investigation 6 months, without lamination, with after feel unchanged, abnormal smells from the patient is unchanged.

7, follicular keratosis effect experimental is improved

Choose 200 15-65 year age bracket have the volunteer of dyskeratosis follicularis as object on probation, be divided into arbitrarily four groups, respectively with embodiment 1,2,3,4, the emulsion of preparation, sooner or later respectively be once applied to follicular keratosis position every day, continuously use one month.Wherein embodiment 1, in 50 examples, man 20 example, female 30 example.Embodiment 2, in 50 examples, man 26 example, female 24 example.Embodiment 3, in 50 examples, man 25 example, female 25 example.Embodiment 4, in 50 examples, man 23 example, female 27 example.

Effect standard: effective: Corium Gallus domesticus skin transference cure, follicular keratosis phenomenon improves significantly; Effective: follicular keratosis phenomenon improves; Invalid: without any change.The results are shown in Table 1:

Table 1 improves follicular keratosis effect expedition

Effect	Effective/people	Effectively/people	Invalid/people	Effective percentage/%
					Embodiment 1	39	5	6	88
Embodiment 2	41	6	3	94
					Embodiment 3	40	5	5	90
Embodiment 4	42	5	3	94

8, resultant effect is investigated

Below utilize effect feeling to come the treatment dyskeratosis follicularis emulsion that Evaluation operation example produces on probation.Adopt public-opinion poll point system, choose 200 15-65 year age bracket the people with dyskeratosis follicularis as object on probation, be divided into arbitrarily four groups, be applied to follicular keratosis position by emulsion prepared by embodiment respectively, twice daily, use one month continuously.Every result of use total score is 10 points: 10 be divided into best result, represents better, very satisfaction; 8 are divided into very well; 5 are divided into and can accept; Less than 5 points is bad, can not accept.Be below every average, the results are shown in Table 2:

Table 2 resultant effect is investigated

Claims

1. treat an emulsion for dyskeratosis follicularis, it is characterized in that, include following material:

2. a kind of emulsion for the treatment of dyskeratosis follicularis according to claim 1, it is characterized in that, include following material: aloe 2ml, American Avocado Tree oil 1ml, Flos Matricariae chamomillae soaks oily 2ml, arabic gum 1.5g, tragakanta 0.5g, sodium alginate 0.4g, Herba Centellae extracting solution 2ml, Radix Glycyrrhizae extract 2ml, Fructus Luffae extracting solution 2ml, Cortex Moutan extracting solution 2ml, Radix Angelicae Sinensis extracting solution 2ml, tretinoin 0.09g, vitamin A 0.1g, carbamide 0.5g, salicylic acid 0.6g, glycerol 4ml, 2% ethyl hydroxybenzoate alcoholic solution 1ml, distilled water 81ml.

3. a kind of emulsion for the treatment of dyskeratosis follicularis according to claim 1, it is characterized in that, include following material: aloe 5ml, American Avocado Tree oil 5ml, Flos Matricariae chamomillae soaks oily 5ml, arabic gum 2g, tragakanta 1g, sodium alginate 0.5g, Herba Centellae extracting solution 5ml, Radix Glycyrrhizae extract 5ml, Fructus Luffae extracting solution 5ml, Cortex Moutan extracting solution 5ml, Radix Angelicae Sinensis extracting solution 5ml, tretinoin 0.15g, vitamin A 0.15g, carbamide 1.0g, salicylic acid 1.0g, glycerol 7ml, 2% ethyl hydroxybenzoate alcoholic solution 2ml, distilled water 105ml.

4. treat a preparation method for the emulsion of dyskeratosis follicularis described in any one of claim 1-3, it is characterized in that, comprise the following steps:

5. a kind of preparation method for the treatment of the emulsion of dyskeratosis follicularis according to claim 4, is characterized in that: described Flos Matricariae chamomillae soaks oil to be prepared by the following method:

6. a kind of preparation method for the treatment of the emulsion of dyskeratosis follicularis according to claim 4, is characterized in that: described Radix Glycyrrhizae extract is prepared by the following method:

7. a kind of preparation method for the treatment of the emulsion of dyskeratosis follicularis according to claim 4, is characterized in that: described Herba Centellae extracting solution is prepared by the following method:

8. a kind of preparation method for the treatment of the emulsion of dyskeratosis follicularis according to claim 4, is characterized in that: described Fructus Luffae extracting solution is prepared by the following method:

9. a kind of preparation method for the treatment of the emulsion of dyskeratosis follicularis according to claim 4, is characterized in that: described Radix Angelicae Sinensis extracting solution is prepared by the following method:

Take Radix Angelicae Sinensis 40-50g, be ground into coarse powder, add 75% alcoholic solution of 10-16 times of Radix Angelicae Sinensis weight, soak 0.25-0.80h, reflux, extract, 0.5-1.5h, obtain filtrate 1 by 3 layers of filtered through gauze; In filtering residue, add 75% alcoholic solution of 10-15 times of filtering residue weight, reflux, extract, 0.5-1.5h, obtain filtrate 2 by 3 layers of filtered through gauze; In filtering residue, add 75% alcoholic solution of 8-10 times of filtering residue weight again, reflux, extract, 0.5-1.5h, obtain filtrate 3 by 3 layers of filtered through gauze; Filtrate 1, filtrate 2, filtrate 3 are merged, temperature be 40-50 DEG C, vacuum is evaporated to the 5-8 of Radix Angelicae Sinensis weight doubly under being 0.05-0.08Pa condition, obtain Radix Angelicae Sinensis extracting solution.

10. a kind of preparation method for the treatment of the emulsion of dyskeratosis follicularis according to claim 4, is characterized in that: described Cortex Moutan extracting solution is prepared by the following method:

Take Cortex Moutan 30-50g, be ground into coarse powder, add 70% alcoholic solution of 10-16 times of Cortex Moutan weight, soak 0.25-0.80h, reflux, extract, 0.5-1.5h, obtain filtrate 1 by 3 layers of filtered through gauze; In filtering residue, add 70% alcoholic solution of 10-15 times of filtering residue weight, reflux, extract, 0.5-1.5h, obtain filtrate 2 by 3 layers of filtered through gauze; In filtering residue, add 70% alcoholic solution of 8-10 times of filtering residue weight again, reflux, extract, 0.5-1.5h, obtain filtrate 3 by 3 layers of filtered through gauze; Filtrate 1, filtrate 2, filtrate 3 are merged, temperature be 40-50 DEG C, vacuum is evaporated to the 5-8 of Cortex Moutan weight doubly under being 0.05-0.08Pa condition, obtain Cortex Moutan extracting solution.