CN105267884A

CN105267884A - Medicine for mitral valve combined aortic lesion heart disease

Info

Publication number: CN105267884A
Application number: CN201510836248.6A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-11-26
Filing date: 2015-11-26
Publication date: 2016-01-27

Abstract

The invention discloses a medicine for mitral valve combined aortic lesion heart disease. The medicine is prepared from the following components by virtue of scientific and reasonable compatibility according to the principles of monarch, minister, assistant and guide drugs: semen allii tuberose, liquorice, ginseng, astragalus, rhizoma curculiginis, radix curcumae, frankincense, cinnamon, the root of red-rooted salvia, codonopsis pilosula, cassia twig, radix ophiopogonis, Angelica sinensis, schisandra chinensis, Rehmannia Glutinosa, ephedra, semen brassicae, oriental wormwood, Scutellaria baicalensis, hawthorn, Pinellia ternata, ligusticum wallichii, tuber fleeceflower stem, semen boitae, Panax pseudoginseng, white paeony root, root of rehmannia, glossy privet fruit, fructus forsythiae, honeysuckle, rhizoma anemarrhenae, radix polygonati officinalis, bighead atractylodes rhizome, white poria, Chinese yam, phaseolus calcaratus, endothelium corneum gigeriae galli, dried tangerine or orange peel, akebiaquinata, the seed of cowherb, rhizoma atractylodis, concha arcae, Artemisia anomala, corydalis tuber, cassia twig, asarum, chuan safflower and lignum dalbergiae odoriferae. The medicine has the advantages of repairing chronic cardiac valve lesion and inhibiting palpitation and expiratory dyspnea, so that the disease symptoms are relieved in a short period, and the curative effect is obvious.

Description

A kind of Bicuspid valve that is used for merges the cardiopathic medicine of aortic disease

Technical field

The present invention relates to a kind of medicine, particularly relate to a kind of for the cardiopathic medicine of Bicuspid valve merging aortic disease.

Background technology

Heart disease is the general name of heart disease, comprises the various heart diseases such as rheumatic heart disease, congenital heart disease, hypertensive heart disease, coronary heart disease, myocarditis.The traditional Chinese medical science is thought: " the main blood of the heart, the lung main force " says that H&L is two organs adjacent in thoracic cavity, and the heart is at front lung rear, and heart is responsible for the motion advancing blood, the main breathing of lung.In prior art, have and use the massage method in the traditional Chinese medical science to carry out auxiliary treatment, custom of keeping on a diet in addition in addition, all use the mode of surgical incision and treat by having Western medicine mostly, the danger of ophthalmic surgical is very high, and Western medicine impels the health regulatory mechanism of patient to degenerate at a high speed, easily causes human body to the dependence of medicine, want to break away from medicine, the function of human body regulating system will be recovered.

Summary of the invention

In view of above-mentioned the deficiencies in the prior art, the one that the object of the present invention is to provide merges the cardiopathic medicine of aortic disease for Bicuspid valve.

For solving the problems of the technologies described above, technical solution of the present invention comprises:

A kind of Bicuspid valve that is used for merges the cardiopathic medicine of aortic disease, and it comprises following component according to weight ratio:

Semen Allii Tuberosi 10 parts-25 parts, 5 parts-10 parts, Radix Glycyrrhizae, Radix Ginseng 1 part-5 parts, the Radix Astragali 2 parts-14 parts, Rhizoma Curculiginis 10 parts-20 parts, Radix Curcumae 10 parts-20 parts, Olibanum 6 parts-10 parts, Cortex Cinnamomi 5 parts-20 parts, Radix Salviae Miltiorrhizae 10 parts-25 parts, Radix Codonopsis 1 part-5 parts, Ramulus Cinnamomi 6 parts-10 parts, Radix Ophiopogonis 10 parts-25 parts, Radix Angelicae Sinensis 5 parts-10 parts, Fructus Schisandrae Chinensis 5 parts-20 parts, 10 parts-20 parts, Radix Rehmanniae Preparata, 1 part-5 parts, Herba Ephedrae, Semen Sinapis Albae 1 part-5 parts, Herba Artemisiae Scopariae 5 parts-10 parts, Radix Scutellariae 10 parts-25 parts, Fructus Crataegi 5 parts-10 parts, the Rhizoma Pinelliae 6 parts-10 parts, Rhizoma Chuanxiong 5 parts-20 parts, Caulis Polygoni Multiflori 10 parts-20 parts, Semen Platycladi 10 parts-25 parts, Radix Notoginseng 5 parts-10 parts, the Radix Paeoniae Alba 6 parts-10 parts, 6 parts-10 parts, the Radix Rehmanniae, Fructus Ligustri Lucidi 10 parts-20 parts, Fructus Forsythiae 10 parts-20 parts, Flos Lonicerae 2 parts-14 parts, the Rhizoma Anemarrhenae 6 parts-10 parts, Rhizoma Polygonati Odorati 6 parts-10 parts, the Rhizoma Atractylodis Macrocephalae 1 part-5 parts, Poria 10 parts-25 parts, Rhizoma Dioscoreae 5 parts-10 parts, Semen Phaseoli 5 parts-10 parts, Endothelium Corneum Gigeriae Galli 1 part-5 parts, Pericarpium Citri Reticulatae 5 parts-10 parts, Caulis Akebiae 2 parts-14 parts, Semen Vaccariae 6 parts-10 parts, Rhizoma Atractylodis 10 parts-25 parts, Concha Arcae 5 parts-10 parts, Herba Artemisiae Anomalae 5 parts-20 parts, Rhizoma Corydalis 5 parts-10 parts, Herba Asari 2 parts-14 parts, Flos Carthami 1 part-5 parts and Lignum Dalbergiae Odoriferae 10 parts-20 parts.

Described medicine, wherein, it comprises following component according to weight ratio:

Semen Allii Tuberosi 15 parts, 8 parts, Radix Glycyrrhizae, Radix Ginseng 3 parts, the Radix Astragali 9 parts, Rhizoma Curculiginis 15 parts, Radix Curcumae 15 parts, Olibanum 8 parts, Cortex Cinnamomi 16 parts, Radix Salviae Miltiorrhizae 17 parts, Radix Codonopsis 4 parts, Ramulus Cinnamomi 8 parts, Radix Ophiopogonis 16 parts, Radix Angelicae Sinensis 7 parts, Fructus Schisandrae Chinensis 13 parts, 15 parts, Radix Rehmanniae Preparata, 3 parts, Herba Ephedrae, Semen Sinapis Albae 4 parts, Herba Artemisiae Scopariae 7 parts, Radix Scutellariae 15 parts, Fructus Crataegi 8 parts, the Rhizoma Pinelliae 7 parts, Rhizoma Chuanxiong 14 parts, Caulis Polygoni Multiflori 15 parts, Semen Platycladi 20 parts, Radix Notoginseng 8 parts, the Radix Paeoniae Alba 8 parts, 8 parts, the Radix Rehmanniae, Fructus Ligustri Lucidi 15 parts, Fructus Forsythiae 15 parts, Flos Lonicerae 10 parts, the Rhizoma Anemarrhenae 8 parts, Rhizoma Polygonati Odorati 8 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Poria 17 parts, Rhizoma Dioscoreae 7 parts, Semen Phaseoli 7 parts, Endothelium Corneum Gigeriae Galli 3 parts, Pericarpium Citri Reticulatae 8 parts, Caulis Akebiae 11 parts, Semen Vaccariae 8 parts, Rhizoma Atractylodis 18 parts, Concha Arcae 8 parts, Herba Artemisiae Anomalae 15 parts, Rhizoma Corydalis 7 parts, Herba Asari 9 parts, Flos Carthami 4 parts and Lignum Dalbergiae Odoriferae 15 parts.

One provided by the invention is used for Bicuspid valve and merges the cardiopathic medicine of aortic disease, the kinds of traditional Chinese medicines such as Fructus Crataegi, the Rhizoma Pinelliae, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Semen Platycladi, Radix Notoginseng are carried out scientific and reasonable compatibility according to the principle of " monarch ", repair chronic cardiac valve lesion, suppress cardiopalmus, dyspneic advantage, within short-term, make disease symptoms be eased, evident in efficacy.Its pharmacological effect is as follows:

Semen Allii Tuberosi, property is pungent, sweet, and temperature, has temperature compensation Liver and kidney, tonifying YANG controlling nocturnal emission with astringent drugs, effect of warm waist knee joint;

Radix Glycyrrhizae, feeble QI, taste is sweet and special, and function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough;

Radix Ginseng, sweet in the mouth, micro-hardship, warm in nature, flat, QI invigorating, Gu de-, promote the production of body fluid, calms the nerves, Fructus Alpiniae Oxyphyllae;

The Radix Astragali, the sweet temperature of property, returns lung meridian, has tonifying Qi and lifting yang, a function that benefit defends consolidating superficial resistance;

Rhizoma Curculiginis, has the effect that reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening and promoting the circulation of blood are subsided a swelling;

Radix Curcumae, pungent, bitter, cold, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood;

Olibanum, pungent, bitter, temperature, blood-activating and qi-promoting pain relieving, detumescence and promoting granulation;

Cortex Cinnamomi, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation;

Radix Salviae Miltiorrhizae, blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle;

Radix Codonopsis, sweet in the mouth, property is put down.Have invigorating the spleen and replenishing QI, quench the thirst, spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid;

Ramulus Cinnamomi, taste acrid, sweet, warm, have complement sun, promoting blood circulation effect;

Radix Ophiopogonis, sweet, micro-hardship, is slightly cold.Lung moistening clears away heart-fire, purge heat and promote the production of body fluid, the preventing or arresting vomiting that reduces phlegm, control row water of coughing;

Radix Angelicae Sinensis, sweet, pungent, warm, enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving;

Fructus Schisandrae Chinensis, astringes the lung, and nourishing kidney is promoted the production of body fluid, and receives antiperspirant, arresting seminal emission;

Radix Rehmanniae Preparata, blood deficiency and yellow complexion, dizzy, palpitation and insomnia;

Herba Ephedrae, it is warm in nature, and acrid in the mouth, micro-hardship, have effect of diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema;

Semen Sinapis Albae, acrid in the mouth, temperature, nontoxic; Warming spleen and stomach for dispelling cold, promoting the circulation of QI eliminating phlegm, the meridian dredging, detumescence poison;

Herba Artemisiae Scopariae, bitter, pungent, be slightly cold; Clearing away heat-damp and promoting diuresis;

Radix Scutellariae, bitter in the mouth, cold in nature, there is effect of heat clearing and damp drying, eliminating fire and detoxication, hemostasis;

Fructus Crataegi, acid is sweet, and tepor, helps digestion long-pending, dissipating blood stasis blood, expelling tenia;

The Rhizoma Pinelliae, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass;

Rhizoma Chuanxiong, acrid in the mouth, temperature, activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain;

Caulis Polygoni Multiflori, bitter in the mouth, warm in nature, nontoxic, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies;

Semen Platycladi, sweet in the mouth, property is put down, tranquilizing by nourishing the heart, loosening bowel to relieve constipation, hidroschesis;

Radix Notoginseng, sweet, micro-hardship, temperature, dissipating blood stasis stops blooding, subduing swelling and relieving pain;

The Radix Paeoniae Alba, bitter, acid, is slightly cold, enriches blood, yin fluid astringing easing the affected liver, relieving spasm to stop pain;

The Radix Rehmanniae, sweet, cold; Help heart and gallbladder gas, peace soul determines soul, controls palpitation with fear, and the bad cardiopulmonary of labor damage;

Fructus Ligustri Lucidi, sweet, bitter, cold, liver and kidney tonifying, clearind deficient heat

Fructus Forsythiae, bitter, cool, heat clearing away, removing toxic substances, eliminating stagnation, detumescence;

Flos Lonicerae, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing;

The Rhizoma Anemarrhenae, property bitter cold, has nourishing YIN to lower pathogenic fire;

Rhizoma Polygonati Odorati, tool yin nourishing, moisturize, heat clearing away, the effect such as to promote the production of body fluid

The Rhizoma Atractylodis Macrocephalae, bitter in the mouth, sweet, warm in nature, invigorating the spleen and benefiting QI, dampness diuretic;

Poria, sweet, light, flat; Eliminating dampness and diuresis; Invigorating the spleen and regulating the stomach; Mind tranquilizing and the heart calming;

Rhizoma Dioscoreae, aid digestion, hold back sweating due to debility, effect of antidiarrheal;

Semen Phaseoli, property is put down, sweet in the mouth, acid; Can be inducing diuresis and reducing edema, heat clearing away jaundice eliminating, removing toxic substances and promoting pus discharge;

Endothelium Corneum Gigeriae Galli, sweet, flat, arresting seminal emission, treating stranguria fossil;

Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature, regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm;

Caulis Akebiae, bitter in the mouth, cold in nature, have inducing diuresis for treating stranguria syndrome, clear away heart-fire relieving restlessness;

Semen Vaccariae, bitter, flat, promoting blood circulation to restore menstrual flow, inducing diuresis for treating stranguria syndrome;

Rhizoma Atractylodis, acrid in the mouth; Bitter; Warm in nature, dehumidifying diaphoresis, stomach invigorating peace spleen, controls flaccidity key medicine;

Concha Arcae, salty in the mouth, property is put down; Expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache;

Herba Artemisiae Anomalae, bitter, temperature; Removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling;

Rhizoma Corydalis, acrid in the mouth, bitter, temperature; Promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain;

Herba Asari, pungent, temperature; Induce sweat cold expelling, and wind-expelling pain-stopping is sensible, warming the lung to resolve fluid-retention;

Flos Carthami, acrid in the mouth, warm in nature; There is promoting blood circulation to restore menstrual flow, effect that blood stasis dispelling relieves the pain;

Lignum Dalbergiae Odoriferae, hemorrhage for incised wound, pain, swelling and pain due to blood stasis.

Clinical data:

For showing the therapeutic effect of medicine of the present invention, the present invention merges through 140 routine Bicuspid valve the clinical research that aortic disease heart disease carries out system, and 140 routine cases all derive from development zone in Qingdao hospital.

Treatment group: choose 60 examples by random method, take Drug therapy of the present invention 7 weeks.

Matched group: choose 60 examples by random method, takes FUFANG DANSHEN PIAN treatment 7 weeks.

Two groups in the state of an illness, sex, age, the course of disease etc. through statistical procedures no significant difference.

Instructions of taking: treatment group: the decoction 150 milliliters sooner or later respectively once taking medicine of the present invention every day, treats 7 weeks.Matched group: give FUFANG DANSHEN PIAN, one time 6, every day 3 times, take after the meal, treat 7 weeks.

Observation index and method

With reference to the standard of " new Chinese medicine guideline of clinical investigations ".

Treatment group, cures 50 examples, effective 10 examples, invalid 0 example, total effective rate 100%.Matched group, cures 30 examples, effective 15 examples, invalid 15 examples, total effective rate 80%.Between two groups, difference has very significant, and treatment group is obviously better than matched group.

Detailed description of the invention

The invention provides a kind of for the cardiopathic medicine of Bicuspid valve merging aortic disease, for making object of the present invention, technical scheme and effect clearly, clearly, the present invention is described in more detail below.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.

Embodiment 1

Merge the cardiopathic medicine of aortic disease for Bicuspid valve, it comprises following component according to weight ratio:

Semen Allii Tuberosi 10 parts, 5 parts, Radix Glycyrrhizae, Radix Ginseng 1 part, the Radix Astragali 2 parts, Rhizoma Curculiginis 10 parts, Radix Curcumae 10 parts, Olibanum 6 parts, Cortex Cinnamomi 5 parts, Radix Salviae Miltiorrhizae 10 parts, Radix Codonopsis 1 part, Ramulus Cinnamomi 6 parts, Radix Ophiopogonis 10 parts, Radix Angelicae Sinensis 5 parts, Fructus Schisandrae Chinensis 5 parts, 10 parts, Radix Rehmanniae Preparata, 1 part, Herba Ephedrae, Semen Sinapis Albae 1 part, Herba Artemisiae Scopariae 5 parts, Radix Scutellariae 10 parts, Fructus Crataegi 5 parts, the Rhizoma Pinelliae 6 parts, Rhizoma Chuanxiong 5 parts, Caulis Polygoni Multiflori 10 parts, Semen Platycladi 10 parts, Radix Notoginseng 5 parts, the Radix Paeoniae Alba 6 parts, 6 parts, the Radix Rehmanniae, Fructus Ligustri Lucidi 10 parts, Fructus Forsythiae 10 parts, Flos Lonicerae 2 parts, the Rhizoma Anemarrhenae 6 parts, Rhizoma Polygonati Odorati 6 parts, the Rhizoma Atractylodis Macrocephalae 1 part, Poria 10 parts, Rhizoma Dioscoreae 5 parts, Semen Phaseoli 5 parts, Endothelium Corneum Gigeriae Galli 1 part, Pericarpium Citri Reticulatae 5 parts, Caulis Akebiae 2 parts, Semen Vaccariae 6 parts of parts, Rhizoma Atractylodis 10 parts, Concha Arcae 5 parts, Herba Artemisiae Anomalae 5 parts, Rhizoma Corydalis 5 parts, Herba Asari 2 parts, Flos Carthami 1 part and Lignum Dalbergiae Odoriferae 10 parts.

The preparation method that treatment Bicuspid valve merges the cardiopathic medicine of aortic disease is as follows:

(1) according to above-mentioned weight by Semen Allii Tuberosi, Radix Glycyrrhizae, Radix Ginseng, the Radix Astragali, Rhizoma Curculiginis, Radix Curcumae, Olibanum, Cortex Cinnamomi, Radix Salviae Miltiorrhizae, Radix Codonopsis, Ramulus Cinnamomi, Radix Ophiopogonis, Radix Angelicae Sinensis, Fructus Schisandrae Chinensis, Radix Rehmanniae Preparata, Herba Ephedrae, Semen Sinapis Albae, Herba Artemisiae Scopariae, Radix Scutellariae, Fructus Crataegi, the Rhizoma Pinelliae, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Semen Platycladi, Radix Notoginseng, the Radix Paeoniae Alba, the Radix Rehmanniae, Fructus Ligustri Lucidi, Fructus Forsythiae, Flos Lonicerae, the Rhizoma Anemarrhenae, Rhizoma Polygonati Odorati, the Rhizoma Atractylodis Macrocephalae, Poria, Rhizoma Dioscoreae, Semen Phaseoli, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae, Caulis Akebiae, Semen Vaccariae, Rhizoma Atractylodis, Concha Arcae, Herba Artemisiae Anomalae, Rhizoma Corydalis, Ramulus Cinnamomi, Herba Asari, Flos Carthami, Lignum Dalbergiae Odoriferae, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:6, soak 30 minutes in water.

(2) mixture in described step (1) and soak by water, after 40 minutes, are filtered and obtain the first filtrate and filtering residue.

(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:4, then decoct 60 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.

Embodiment 2

Embodiment 3

Semen Allii Tuberosi 25 parts, 10 parts, Radix Glycyrrhizae, Radix Ginseng 5 parts, the Radix Astragali 14 parts, Rhizoma Curculiginis 20 parts, Radix Curcumae 20 parts, Olibanum 10 parts, Cortex Cinnamomi 20 parts, Radix Salviae Miltiorrhizae 25 parts, Radix Codonopsis 5 parts, Ramulus Cinnamomi 10 parts, Radix Ophiopogonis 25 parts, Radix Angelicae Sinensis 10 parts, Fructus Schisandrae Chinensis 20 parts, 20 parts, Radix Rehmanniae Preparata, 5 parts, Herba Ephedrae, Semen Sinapis Albae 5 parts, Herba Artemisiae Scopariae 10 parts, Radix Scutellariae 25 parts, Fructus Crataegi 10 parts, the Rhizoma Pinelliae 10 parts, Rhizoma Chuanxiong 20 parts, Caulis Polygoni Multiflori 20 parts, Semen Platycladi 25 parts, Radix Notoginseng 10 parts, the Radix Paeoniae Alba 10 parts, 10 parts, the Radix Rehmanniae, Fructus Ligustri Lucidi 20 parts, Fructus Forsythiae 20 parts, Flos Lonicerae 14 parts, the Rhizoma Anemarrhenae 10 parts, Rhizoma Polygonati Odorati 10 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Poria 25 parts, Rhizoma Dioscoreae 10 parts, Semen Phaseoli 10 parts, Endothelium Corneum Gigeriae Galli 5 parts, Pericarpium Citri Reticulatae 10 parts, Caulis Akebiae 14 parts, Semen Vaccariae 10 parts, Rhizoma Atractylodis 25 parts, Concha Arcae 10 parts, Herba Artemisiae Anomalae 20 parts, Rhizoma Corydalis 10 parts, Herba Asari 14 parts, Flos Carthami 5 parts and Lignum Dalbergiae Odoriferae 20 parts.

Certainly; more than illustrate and be only preferred embodiment of the present invention; the present invention is not limited to enumerate above-described embodiment; should be noted that; any those of ordinary skill in the art are under the instruction of this description; made all equivalently to substitute, obvious variant, within the essential scope all dropping on this description, protection of the present invention ought to be subject to.

Claims

1. merge the cardiopathic medicine of aortic disease for Bicuspid valve, it comprises following component according to weight ratio:

2. want the medicine described in 1 according to right, it is characterized in that, it comprises following component according to weight ratio: