CN105123699A - Miticide and insecticide composite containing thymol and pyriproxyfen - Google Patents
Miticide and insecticide composite containing thymol and pyriproxyfen Download PDFInfo
- Publication number
- CN105123699A CN105123699A CN201510688204.3A CN201510688204A CN105123699A CN 105123699 A CN105123699 A CN 105123699A CN 201510688204 A CN201510688204 A CN 201510688204A CN 105123699 A CN105123699 A CN 105123699A
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- CN
- China
- Prior art keywords
- thymol
- nylar
- composite
- pyriproxyfen
- insecticide
- Prior art date
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- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 title claims abstract description 111
- 239000005844 Thymol Substances 0.000 title claims abstract description 56
- 229960000790 thymol Drugs 0.000 title claims abstract description 56
- NHDHVHZZCFYRSB-UHFFFAOYSA-N pyriproxyfen Chemical compound C=1C=CC=NC=1OC(C)COC(C=C1)=CC=C1OC1=CC=CC=C1 NHDHVHZZCFYRSB-UHFFFAOYSA-N 0.000 title claims abstract description 53
- 239000002917 insecticide Substances 0.000 title claims abstract description 14
- 239000000642 acaricide Substances 0.000 title claims abstract description 10
- 239000002131 composite material Substances 0.000 title abstract description 9
- 239000005927 Pyriproxyfen Substances 0.000 title abstract description 6
- 241000500437 Plutella xylostella Species 0.000 claims abstract description 17
- 241000526200 Cacopsylla pyri Species 0.000 claims abstract description 5
- 241000256247 Spodoptera exigua Species 0.000 claims abstract description 5
- 241000344252 Tetranychus piercei Species 0.000 claims abstract description 5
- 241001414989 Thysanoptera Species 0.000 claims abstract description 5
- 239000000203 mixture Substances 0.000 claims description 20
- 241000238631 Hexapoda Species 0.000 claims description 15
- 239000004480 active ingredient Substances 0.000 claims description 11
- 230000000895 acaricidal effect Effects 0.000 claims description 8
- 241000344246 Tetranychus cinnabarinus Species 0.000 claims description 4
- 241000819999 Nymphes Species 0.000 claims description 3
- 239000002671 adjuvant Substances 0.000 claims 1
- 125000003639 thymyl group Chemical group C1(=CC(C)=CC=C1C(C)C)* 0.000 claims 1
- 241000607479 Yersinia pestis Species 0.000 abstract description 12
- 239000000575 pesticide Substances 0.000 abstract description 9
- 230000002195 synergetic effect Effects 0.000 abstract description 6
- 238000012360 testing method Methods 0.000 abstract description 6
- 238000011161 development Methods 0.000 abstract description 5
- 230000000853 biopesticidal effect Effects 0.000 abstract description 4
- 230000000749 insecticidal effect Effects 0.000 abstract description 4
- 238000001228 spectrum Methods 0.000 abstract description 3
- 230000003111 delayed effect Effects 0.000 abstract description 2
- 239000000447 pesticide residue Substances 0.000 abstract description 2
- 239000000470 constituent Substances 0.000 abstract 3
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 230000003129 miticidal effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000004321 preservation Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 18
- 238000000034 method Methods 0.000 description 13
- 239000003795 chemical substances by application Substances 0.000 description 8
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 8
- 230000008569 process Effects 0.000 description 7
- 231100000419 toxicity Toxicity 0.000 description 7
- 230000001988 toxicity Effects 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 239000003905 agrochemical Substances 0.000 description 5
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- 239000002270 dispersing agent Substances 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- -1 synergist Substances 0.000 description 5
- 239000000080 wetting agent Substances 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 238000011835 investigation Methods 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 239000003381 stabilizer Substances 0.000 description 4
- 235000006008 Brassica napus var napus Nutrition 0.000 description 3
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 3
- 241001674939 Caulanthus Species 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical group OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000013530 defoamer Substances 0.000 description 3
- 239000007884 disintegrant Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000003995 emulsifying agent Substances 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 231100000225 lethality Toxicity 0.000 description 3
- 239000004530 micro-emulsion Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
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- 238000009736 wetting Methods 0.000 description 3
- 239000005995 Aluminium silicate Substances 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 235000012211 aluminium silicate Nutrition 0.000 description 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- 239000000440 bentonite Substances 0.000 description 2
- 229910000278 bentonite Inorganic materials 0.000 description 2
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical group O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 2
- 230000008859 change Effects 0.000 description 2
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- 238000001990 intravenous administration Methods 0.000 description 2
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 2
- 231100000053 low toxicity Toxicity 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000010534 mechanism of action Effects 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 231100000572 poisoning Toxicity 0.000 description 2
- 230000000607 poisoning effect Effects 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 description 2
- 239000004576 sand Substances 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 229920002545 silicone oil Polymers 0.000 description 2
- 239000001509 sodium citrate Substances 0.000 description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- GLGNXYJARSMNGJ-VKTIVEEGSA-N (1s,2s,3r,4r)-3-[[5-chloro-2-[(1-ethyl-6-methoxy-2-oxo-4,5-dihydro-3h-1-benzazepin-7-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide Chemical compound CCN1C(=O)CCCC2=C(OC)C(NC=3N=C(C(=CN=3)Cl)N[C@H]3[C@H]([C@@]4([H])C[C@@]3(C=C4)[H])C(N)=O)=CC=C21 GLGNXYJARSMNGJ-VKTIVEEGSA-N 0.000 description 1
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 description 1
- IJALWSVNUBBQRA-UHFFFAOYSA-N 4-Isopropyl-3-methylphenol Chemical compound CC(C)C1=CC=C(O)C=C1C IJALWSVNUBBQRA-UHFFFAOYSA-N 0.000 description 1
- RNMDNPCBIKJCQP-UHFFFAOYSA-N 5-nonyl-7-oxabicyclo[4.1.0]hepta-1,3,5-trien-2-ol Chemical compound C(CCCCCCCC)C1=C2C(=C(C=C1)O)O2 RNMDNPCBIKJCQP-UHFFFAOYSA-N 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 241000254127 Bemisia tabaci Species 0.000 description 1
- 208000019300 CLIPPERS Diseases 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000258937 Hemiptera Species 0.000 description 1
- 102000003960 Ligases Human genes 0.000 description 1
- 108090000364 Ligases Proteins 0.000 description 1
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical group OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 1
- 241001634931 Oligonychus biharensis Species 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000004283 Sodium sorbate Substances 0.000 description 1
- 241000985245 Spodoptera litura Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 125000002877 alkyl aryl group Chemical group 0.000 description 1
- 150000008051 alkyl sulfates Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001857 anti-mycotic effect Effects 0.000 description 1
- 239000002543 antimycotic Substances 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 230000009910 autonomic response Effects 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 229920003064 carboxyethyl cellulose Polymers 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 208000021930 chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids Diseases 0.000 description 1
- 229940125758 compound 15 Drugs 0.000 description 1
- 238000000205 computational method Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000037123 dental health Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 239000003063 flame retardant Substances 0.000 description 1
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 239000002950 juvenile hormone derivative Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000000361 pesticidal effect Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- LROWVYNUWKVTCU-STWYSWDKSA-M sodium sorbate Chemical compound [Na+].C\C=C\C=C\C([O-])=O LROWVYNUWKVTCU-STWYSWDKSA-M 0.000 description 1
- 235000019250 sodium sorbate Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
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- 239000008107 starch Substances 0.000 description 1
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- 238000003756 stirring Methods 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
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- 238000010998 test method Methods 0.000 description 1
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- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
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- 230000001018 virulence Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a miticide and insecticide composite containing thymol and pyriproxyfen. The composite comprises the first effective constituent thymol, the second effective constituent pyriproxyfen and common auxiliary constituents, wherein the weight ratio of thymol to pyriproxyfen is 50:1-1:50. A large number of indoor and outdoor tests show that the composite has a remarkable synergistic effect, the miticidal and insecticidal spectrum is enlarged, and the composite can be used for controlling multiple agricultural pests including tetrangychus cinnabarinus, tetranychus piercei, nymphs, thrips, plutella xylostella, beet armyworms and pear psyllid and can also achieve preservation, freshness keeping and oxidation resistance; meanwhile, due to the reduction of pesticide application, the number of pesticide residues on crops is reduced, environment pollution is relieved, the generation of drug resistance of pests is delayed, the properties meet the development requirement of biopesticides, and the composite has broad application prospects in biopesticide development.
Description
Technical field
The present invention relates to composition pesticide and application, specifically with the composition pesticide that Thymol and Nylar are active ingredient, be applicable to the pest such as control Tetranychus cinnabarinus, Tetranychus piercei, nymph, thrips, diamond-back moth, beet armyworm, pear psyllid.
Background technology
Thymol: Thymol is separated at first and obtains and gain the name from grass hundred.The chemical name of Thymol is thymol, chemical formula C10H14O, molecular weight 150.22.Be white to light yellow crystalline powder under normal temperature, boiling point 233 DEG C, fusing point 48 – 51 DEG C.Thymol has anti-corrosive properties, and toxicity is lower than phenol, has medical value, can be used in dental health article; It also has antimycotic and parasite function, can be used to process wound, stores dissec etc.; Because it has phenols smell, be also usually used in pest repellant.Effectively can prevent and treat the various agricultural evil mites such as Tetranychus cinnabarinus, Tetranychus piercei, Oligonychus biharensis, and safety, low toxicity.Thymol is plant resource active component, is used at present making spices, preservative, medical bactericide and pest repellant, and safety is high.This material is easy to obtain, stable chemical nature, and toxicity is low, easily degrades in the environment, the demand for development of these characteristic conforms biopesticides, has broad application prospects as biopesticide exploitation.
Nylar: the novel pesticide belonging to juvenoid, the mechanism of action is the inhibitor of chitin synthetase.Have good control efficiency to Bemisia tabaci, scale insect, diamond-back moth, beet armyworm, prodenia litura, pear psyllid, thrips etc., this product has good control efficiency to the sanitary insect pest such as fly, mosquito simultaneously.
The resistance problems of pest is global problems, is the emphasis problem that agricultural science and technology worker pays close attention to always.Along with the impact on the continuity year in year out of Chemical Control of Harmful Insects, the increase of Pesticide use amount and the not factor such as scientifical use agricultural chemicals, cause pest resistance day by day serious, the pest species producing resistance is on the increase.Meanwhile, due to the use agricultural chemicals of high strength, result in that Practice for Pesticide Residue in Agricultural Products exceeds standard, the series of problems such as contaminated environment and the increase of peasant's drug cost, be unfavorable for the sustainable development of agricultural.
Therefore, development is efficient, low toxicity, low-residual, the different mechanism of action, have again the complex preparation of synergistic function simultaneously, not only contribute to the generation delaying pest resistance to insecticide, but also the service life of pesticide species can be extended, reduce using dosage, cost-saving, reduce the pollution to environment.
Summary of the invention
The compounded formula screening of the present inventor's p-Thymol and Nylar conducts in-depth research, find that Thymol and Nylar carry out composite, within the scope of certain compound proportion, there is obvious synergistic function, in actual use simultaneously, expand insecticidal spectrum, to insect agriculturally, as Tetranychus cinnabarinus, Tetranychus piercei, nymph, thrips, diamond-back moth, beet armyworm, pear psyllid etc. have outstanding control efficiency, after further study, the present invention is completed.
Another object of the present invention is to the insecticide and acaricide containing Thymol and Nylar, the generation that in use can reduce dosage, reduce the residual quantity of agricultural chemicals on crops, delay pest resistance to insecticide, it can also be made to be used alone to compare than single dose to the control efficiency of various insect and to significantly improve, laborsaving, economical, reduce farmer's burdens.
Technical solution of the present invention: a kind of insecticide and acaricide containing Thymol and Nylar, with Thymol and Nylar for active ingredient, the weight ratio of Thymol and Nylar is 50:1 ~ 1:50, Thymol and Nylar weight summation percentage by weight are in the composition 1% ~ 55%, and all the other are allow in agricultural chemicals to use and acceptable auxiliary element.
Described auxiliary element is one or more the combination in solvent, emulsifier, wetting agent, dispersant, stabilizing agent, antifreezing agent, thickener, disintegrant, binding agent, defoamer, bleeding agent, synergist, fire retardant and filler, above material is known substance conventional in pesticidal preparations, change to some extent according to being prepared into the different formulations of pesticide, but be not particularly limited.
The present invention can be prepared into any one formulation that applicable agricultural production uses by known method, reasonable formulation has suspending agent, aqueous emulsion, microemulsion, water dispersible granules, wetting powder.
The frequency of administration of the present composition and amount of application change with crops, insect, weather condition and have small variations, can by the object using suitable dosage reach effectively control.
Compared with prior art, the invention has the advantages that:
1, Thymol and pyriproxyfen compound have synergistic function, be used alone the control efficiency significantly improved insect, expand insecticidal spectrum simultaneously than single dose, solve the defect to some insect weak effect when single dose is used alone.
2, Thymol and Nylar two kinds of active ingredients composite, decrease Pesticide use amount, reduce use cost, alleviate pollution to environment, delayed the generation of pest resistance to insecticide, add the service life of agricultural chemicals.
Embodiment
In order to understand essence of the present invention better, below in conjunction with embodiment, content of the present invention is described further, but can not limitation of the present invention be considered as.
Formulation Example
In following each embodiment, active ingredient adopts the former medicine of 95% Thymol and the former medicine of 97% Nylar, and each component percentages is weight percentage.
Embodiment 1:10% Thymol Nylar suspending agent.
Thymol 5%, Nylar 5%, alkylnaphthalene sulfonate 10%, alkylphenol-polyethenoxy base ether phosphate 10%, xanthans 2%, glycerine 2%, silicone oil 0.1%, deionized water supplies 100%.Above-mentioned active ingredient, dispersant, wetting agent, thickener, antifreezing agent, defoamer and deionized water are mixed, sand milling in high speed shear dispersion, sand mill, the high dispersive formed in water-medium, stable suspension system, can obtain 10% Thymol Nylar suspending agent.
Embodiment 2:15% Thymol Nylar aqueous emulsion.
Nylar 6%, Nylar 9%, vegetable oil resin 15%, polyoxyethylene nonylphenol ether 10%, polycarboxylate 10%, sodium sorbate 1%, glycerine 1%, deionized water supplies 100%.Above-mentioned active ingredient, solvent, emulsifier, dispersant and stabilizing agent are mixed to form oil phase, antifreezing agent dissolves and forms aqueous phase in water, slowly oil phase is added in aqueous phase under clipper effect, and continue to shear about 30 minutes, 15% Thymol Nylar aqueous emulsion can be obtained.
Embodiment 3:20% Thymol Nylar microemulsion.
Thymol 10%, Nylar 10%, cyclohexanone 20%, styrylphenol polyoxyethylene ether 15%, sodium citrate 2%, organosilicon 1%, azone 2%, deionized water supplies 100%.Active ingredient solvent is dissolved completely, and then add emulsifier, stabilizing agent, bleeding agent, synergist mix, finally add deionized water, after fully stirring, 20% Thymol Nylar microemulsion can be obtained.
Embodiment 4:40% Thymol Nylar wetting powder.
Thymol 20%, Nylar 20%, alkylaryl APEO 6%, calcium dodecyl benzene sulfonate 8%, diatomite supplies 100%.By above-mentioned, active ingredient, dispersant, wetting agent and filler are mixed, again through air-flow crushing after mechanical crushing, mix, 40% Thymol Nylar 70% wetting powder can be obtained.
Embodiment 5:50% Thymol Nylar water dispersible granules.
Thymol 20%, Nylar 30%, naphthalenesulfonate formaldehyde condensation compound 15%, alkyl sulfate 10%, urea 2%, polyvinyl alcohol 2%, kaolin supplies 100%.Above-mentioned active ingredient, dispersant, wetting agent, disintegrant, binding agent and filler are mixed, pulverize with micro jet, through mediating, then adding in fluidized-bed granulation dryer and carrying out granulation, drying, screening, 50% Thymol Nylar water dispersible granules can be obtained.
Described wetting agent is selected from lauryl sodium sulfate, calcium dodecyl benzene sulfonate, alkylbenzenesulfonate polyoxyethylene triphen phosphenylic acid salt dimly, spaonin powder, in one or more.
Described disintegrant is selected from bentonite, aluminium chloride, citric acid, one or more in sodium bicarbonate.
Described thickener is selected from xanthans, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, in polyvinyl alcohol one or more.
Described stabilizing agent is selected from sodium citrate, the one in resorcinol.
Described antifreezing agent is selected from ethylene glycol, one or more in propane diols.
Described defoamer is selected from silicone oil, silicone compound, one or more of C8-10 fatty alcohol.
Described filler is selected from kaolin, diatomite, bentonite, attapulgite, one or more in starch.
The indoor biological determination of activity of insecticide and acaricide of the present invention and field efficacy checking.
1, Thymol and Nylar are to the indoor joint toxicity measuring of diamond-back moth.
For examination worm: select indoor to raise for 5 generations continuously and the third-instar larvae of its Individual Size responsive type diamond-back moth consistent with physiological status.Temperature (25 ± 2) DEG C.Relative moisture 65% ± 5%, periodicity of illumination 12/12h (L/D).
Reagent agent: the former medicine of 97% Nylar and the former medicine of 95% Nylar.
Experimental procedure
Medicament is prepared: first dissolve former medicine with cyclohexanone, appropriate two former medicines are made into several different ratio by the result according to preliminary experiment, then it is stand-by with cyclohexanone, each process to be diluted to several concentration gradients respectively.
The drop method adopting NY/T1154.1-2006 to recommend measures.By micro intravenous drip device solvent clean, regulate dropper to stand-by state.The examination worm CO2 mild paralysis choosing neat and consistent with writing brush is placed in 9cm culture dish, then with micro intravenous drip device, medicament is dripped to the belly of polypide by head, every some drops physic liquor 0.1L, the process of the corresponding cyclohexanone contained with drop 0.1L is contrast, examination worm after drop is moved to (28 ± 2) DEG C, normally cultivates in the culture dish of relative moisture 75%.Often process and repeat for 4 times, often repeat 20 examination worms.
Control time: 24h investigation examination worm death condition (judging that examination worm death standard gently stings without autonomic response with pin) after process, record total borer population and dead borer population.
Data statistics and analysis: according to investigation statistics, calculate the corrected mortality of each process.And adopt the abundant method of Sun Yun to calculate the co-toxicity coefficient (CTC value) of mixture with reference to NY/T1154.1-2006.If contrast lethality, <5%, does not correct, and contrast lethality is between 5%-20%, and by the hardships of formula life, date depressed, the refinement of a good life corrects, and contrast lethality >20%, test need be reformed.
Be independent variable X with the logarithm value of drug concentration (mg/L), with the probability value of corrected mortality for dependent variable y, set up virulence regression equation formula respectively, the EC50 adopting DPS software to calculate single dose and each proportioning mixture calculates co-toxicity coefficient (CTC) according to the abundant method of Sun Yun.Co-toxicity coefficient CTC, computing formula is as follows: (take Thymol as standard agent, its toxicity index is 100):
EC50 × 100 of the EC50/ Nylar of toxicity index (the TI)=Thymol of Nylar
EC50 × 100 of the EC50/M of true toxicity index (the ATI)=Thymol of M
TI × P Nylar of TI × P Thymol+Nylar of theoretical toxicity index (the TTI)=Thymol of M
TTI × 100 of the ATI/M of co-toxicity coefficient (the CTC)=M of M
In formula:
M is the mixture of Thymol and Nylar different ratio
P Thymol is the ratio of Thymol shared by mixture
P Nylar is the ratio of Nylar shared by mixture.
Toxicity test result:
Table 1 Thymol and Nylar are to the indoor measurement result of diamond-back moth
As can be seen from Table 1, by active ingredient Thymol and Nylar, its malicious coefficient when 50:1 ~ 1:50 (by weight) dilutes all is greater than 120, show certain synergistic effect, wherein Thymol and Nylar are that the synergistic effect of 1:20 ~ 20:1 is the most obvious.Result of the test shows, Thymol and pyriproxyfen compound all have higher activity to diamond-back moth in room conditions, advises carrying out further field control effectiveness test to suitable proportion about 1:20 ~ 20:1 mixture preparation, to evaluate its field practical application effect.
2, field trial control diamond-back moth
2.1 test method
Test is carried out at old city town, Dengmai County, Hainan Province truck garden.Routine is carried out to water spray by each process design concentration.Spraying equipment is WF-16 type knapsack hand sprayer, and shower nozzle is single fan nozzle, and operating pressure is 0.2-0.4Mpa, and spray amount is 0.36-0.48L/min, carries out routine spraying, makes every effort to evenly thoughtful during spray medicine.During dispenser, field diamond-back moth is 1 ~ 2 instar larvae peak period.
2.2 investigation method
Press diagonal 5 sampling in dispenser Qian Mei community, choose wild cabbage 2 ~ 3 strain having Eggs of Diamondback Moth and larva at often.Diamondback moth larvae head number in probability demarcation strain, in this, as insect population radix before dispenser.Within the 7th day, 14 days, 21 days after dispenser, investigate the diamondback moth larvae number determining residual survival in strain respectively.To correct Revision insect recluced rate as control efficiency.
2.3 drug effect computational methods
Revision insect recluced rate (%)=(after medicine prelarva number-medicine larva number)/medicine prelarva number × 100
Preventive effect (%)=(treatment region Revision insect recluced rate-contrast Revision insect recluced rate)/(100-check plot Revision insect recluced rate) × 100.
2.4 poisoning investigation methods
Within 7 days after medicine, observe wild cabbage growing state, estimate medicament to wild cabbage without poisoning.
2.5 table 2 test of pesticide effectiveness results
As can be seen from Table 2, the Mixed Pharmacy of different proportion, field experiment is carried out by different consumptions, after medicine, it is better than contrasting medicament to the control efficiency of diamond-back moth, diamond-back moth instant effect is prevented and treated so that 10:10 ratio is composite with Thymol and Nylar, efficiency time is long, and control efficiency is good, and insecticidal effect increases progressively along with the increase of consumption.This mixture; effectively can control the harm of diamond-back moth to host; to the raising of quality of vegetable with increase production significant; there is stronger popularizing value; so; produce very large economic worth in research and development of the present invention and promotion conference, the increasing both production and income of the peasant household in vast vegetables, fruit tree producing region and the protection tool of local environment are of great significance.
Claims (4)
1. a kind of insecticide and acaricide containing Thymol and Nylar provided by the present invention, it is characterized in that: active ingredient is Thymol and Nylar, wherein the weight ratio of Thymol and Nylar is 50:1 ~ 1:50, and Thymol and Nylar gross weight percentage composition is in the composition 1 ~ 55%.
2. a kind of insecticide and acaricide containing Thymol and Nylar according to claim 1, is characterized in that: described composition also contains insecticides adjuvant, to make the application forms of applicable agricultural use.
3. a kind of insecticide and acaricide containing Thymol and Nylar according to claim 1, is applicable to the insect prevented and treated agriculturally.
4. a kind of insecticide and acaricide containing Thymol and Nylar according to claim 3, is characterized in that: described insect is Tetranychus cinnabarinus, Tetranychus piercei, nymph, thrips, diamond-back moth, beet armyworm, pear psyllid.
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| CN110037033A (en) * | 2019-05-20 | 2019-07-23 | 海南博士威农用化学有限公司 | A kind of Pesticidal combination and its preparation containing capillary |
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