CN105124578A - Health-care food - Google Patents
Health-care food Download PDFInfo
- Publication number
- CN105124578A CN105124578A CN201510558745.4A CN201510558745A CN105124578A CN 105124578 A CN105124578 A CN 105124578A CN 201510558745 A CN201510558745 A CN 201510558745A CN 105124578 A CN105124578 A CN 105124578A
- Authority
- CN
- China
- Prior art keywords
- health
- ginseng
- care food
- test
- root
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000013305 food Nutrition 0.000 title abstract description 6
- 239000000843 powder Substances 0.000 claims abstract description 22
- 241000222336 Ganoderma Species 0.000 claims abstract description 11
- 241000026010 Dendrobium candidum Species 0.000 claims abstract description 10
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 10
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 10
- 240000005373 Panax quinquefolius Species 0.000 claims abstract description 10
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 10
- 244000197580 Poria cocos Species 0.000 claims abstract description 10
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 10
- 239000002994 raw material Substances 0.000 claims abstract description 5
- 238000000034 method Methods 0.000 claims description 20
- 235000013402 health food Nutrition 0.000 claims description 15
- 241000894006 Bacteria Species 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 10
- 241000427159 Achyranthes Species 0.000 claims description 9
- 244000068988 Glycine max Species 0.000 claims description 9
- 235000010469 Glycine max Nutrition 0.000 claims description 9
- 239000009636 Huang Qi Substances 0.000 claims description 9
- 240000007164 Salvia officinalis Species 0.000 claims description 9
- 235000005412 red sage Nutrition 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 4
- 238000003809 water extraction Methods 0.000 claims description 4
- 239000007902 hard capsule Substances 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 2
- 239000007901 soft capsule Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 238000012360 testing method Methods 0.000 abstract description 42
- 210000004369 blood Anatomy 0.000 abstract description 14
- 239000008280 blood Substances 0.000 abstract description 14
- 230000036039 immunity Effects 0.000 abstract description 7
- 235000013557 nattō Nutrition 0.000 abstract description 3
- 150000002632 lipids Chemical class 0.000 abstract description 2
- 238000005728 strengthening Methods 0.000 abstract description 2
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 241001236817 Paecilomyces <Clavicipitaceae> Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 238000013329 compounding Methods 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 33
- 230000006870 function Effects 0.000 description 20
- 230000036737 immune function Effects 0.000 description 12
- 230000000694 effects Effects 0.000 description 11
- 210000002540 macrophage Anatomy 0.000 description 9
- 241001465754 Metazoa Species 0.000 description 8
- 230000036541 health Effects 0.000 description 8
- 210000001616 monocyte Anatomy 0.000 description 8
- 230000000242 pagocytic effect Effects 0.000 description 8
- 230000000052 comparative effect Effects 0.000 description 7
- 230000001939 inductive effect Effects 0.000 description 7
- 238000001543 one-way ANOVA Methods 0.000 description 7
- LOTKRQAVGJMPNV-UHFFFAOYSA-N 1-fluoro-2,4-dinitrobenzene Chemical compound [O-][N+](=O)C1=CC=C(F)C([N+]([O-])=O)=C1 LOTKRQAVGJMPNV-UHFFFAOYSA-N 0.000 description 6
- 230000001413 cellular effect Effects 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 238000001514 detection method Methods 0.000 description 6
- 210000004698 lymphocyte Anatomy 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- 241000287828 Gallus gallus Species 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 5
- 210000003743 erythrocyte Anatomy 0.000 description 5
- 239000000796 flavoring agent Substances 0.000 description 5
- 235000019634 flavors Nutrition 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 210000003024 peritoneal macrophage Anatomy 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 230000006698 induction Effects 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 230000007306 turnover Effects 0.000 description 4
- 241000190633 Cordyceps Species 0.000 description 3
- 206010013935 Dysmenorrhoea Diseases 0.000 description 3
- 108010006464 Hemolysin Proteins Proteins 0.000 description 3
- 208000032843 Hemorrhage Diseases 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 239000003228 hemolysin Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 231100000862 numbness Toxicity 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- 206010018910 Haemolysis Diseases 0.000 description 2
- 208000037093 Menstruation Disturbances Diseases 0.000 description 2
- 206010027339 Menstruation irregular Diseases 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 206010046788 Uterine haemorrhage Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 230000002402 anti-lipaemic effect Effects 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- -1 by high Substances 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000011207 functional examination Methods 0.000 description 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 239000007887 hard shell capsule Substances 0.000 description 2
- 230000008588 hemolysis Effects 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 206010033675 panniculitis Diseases 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 210000000697 sensory organ Anatomy 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 230000001131 transforming effect Effects 0.000 description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- PFRQBZFETXBLTP-RCIYGOBDSA-N 2-[(2e,6e,10e,14e,18e)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3-methyl-1,4-dihydronaphthalene-1,4-dione Chemical compound C1=CC=C2C(=O)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)=C(C)C(=O)C2=C1 PFRQBZFETXBLTP-RCIYGOBDSA-N 0.000 description 1
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 102000040350 B family Human genes 0.000 description 1
- 108091072128 B family Proteins 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 206010013789 Dry throat Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 206010014025 Ear swelling Diseases 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 108010024636 Glutathione Proteins 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 102000003855 L-lactate dehydrogenase Human genes 0.000 description 1
- 108700023483 L-lactate dehydrogenases Proteins 0.000 description 1
- 102000016943 Muramidase Human genes 0.000 description 1
- 108010014251 Muramidase Proteins 0.000 description 1
- 101000981253 Mus musculus GPI-linked NAD(P)(+)-arginine ADP-ribosyltransferase 1 Proteins 0.000 description 1
- 240000001307 Myosotis scorpioides Species 0.000 description 1
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 description 1
- 241001248610 Ophiocordyceps sinensis Species 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 206010057249 Phagocytosis Diseases 0.000 description 1
- 241000222341 Polyporaceae Species 0.000 description 1
- 208000037062 Polyps Diseases 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 239000012980 RPMI-1640 medium Substances 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 241000238370 Sepia Species 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 102000019197 Superoxide Dismutase Human genes 0.000 description 1
- 108010012715 Superoxide dismutase Proteins 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 229960003180 glutathione Drugs 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- LVPMIMZXDYBCDF-UHFFFAOYSA-N isocinchomeronic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)N=C1 LVPMIMZXDYBCDF-UHFFFAOYSA-N 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 150000002515 isoflavone derivatives Chemical class 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 206010025135 lupus erythematosus Diseases 0.000 description 1
- 229960000274 lysozyme Drugs 0.000 description 1
- 235000010335 lysozyme Nutrition 0.000 description 1
- 239000004325 lysozyme Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229940086319 nattokinase Drugs 0.000 description 1
- 108010073682 nattokinase Proteins 0.000 description 1
- 210000000822 natural killer cell Anatomy 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000008782 phagocytosis Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 235000019419 proteases Nutrition 0.000 description 1
- GJAWHXHKYYXBSV-UHFFFAOYSA-N pyridinedicarboxylic acid Natural products OC(=O)C1=CC=CN=C1C(O)=O GJAWHXHKYYXBSV-UHFFFAOYSA-N 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a health-care food. The health-care food contains the following raw materials of paecilomyces hepialid powder, glossy ganoderma, freeze-dried natto powder, poria cocos, astragalus membranaceus, radix achyranthis bidentatae, Chinese angelica, dendrobium candidum, American ginseng, radix salviae miltiorrhizae and pseudo-ginseng. According to the health-care food, the selected raw materials are scientific and reasonable in compounding ratio, foretaste tests on human bodies prove that the health-care food has favorable effects of improving immunity, strengthening constitutions and assisting in reducing blood lipid.
Description
Technical field
The present invention relates to a kind of health food, especially a kind of there is good raising immunity, build up health, the health food of auxiliary antilipemic effect.
Background technology
According to the World Health Organization's statistics display in recent years, the people in the whole world nearly more than 70% is in the third state and sub-health state, and is multiplely born in professional population, and thus inferior health is otherwise known as " new century is sick ".Data analysis according to " the large investigation of Chinese city health status " shows, " White Bone Demon " (white collar, backbone, elite) crowd's sub-health state ratio in China's main flow city reaches 76%, be in overwork state close to sixty percent, " Healthy People " ratio extremely low (less than 3%) truly.In the salt of the earth of 35 to 50 years old and middle booming income crowd, " biological age " overage trend was obviously accelerated, average more than " physiological age " about 10 years.
Summary of the invention
The invention provides a kind of health food, good raising immunity can be played, build up health, auxiliary antilipemic effect.
The present invention realizes with following technical scheme: health food of the present invention is made up of the common hybrid process of the raw material of following portions by weight: peacilomyce hepiahi bacterium powder 2-6 part, glossy ganoderma 1-3 part, freeze dry powder of fermented soybean 8-16 part, Poria cocos 0.2-0.5 part, Radix Astragali 0.4-1 part, root of bidentate achyranthes 0.3-0.6 part, Radix Angelicae Sinensis 1-3 part, dendrobium candidum 0.2-0.4 part, American Ginseng 3-8 part, red sage root 0.5-1 part, pseudo-ginseng 1-2 part.
Preparation method of the present invention, comprise the following steps: glossy ganoderma, Poria cocos, the Radix Astragali, the root of bidentate achyranthes, Radix Angelicae Sinensis, dendrobium candidum, American Ginseng, the red sage root, pseudo-ginseng are mixed by weight proportion, then conveniently water extraction mode extracts twice, after merging extracted twice liquid, concentrated spray is dry, mix with the peacilomyce hepiahi bacterium powder of formula ratio, freeze dry powder of fermented soybean again, add auxiliary material and can obtain granule, tablet, hard capsule, soft capsule through corresponding technique.
Peacilomyce hepiahi bacterium powder is the substitute of natural cordyceps in pharmacy industry and food industry.Be separated from natural cordyceps and obtain Chinese caterpillar fungus hypha, through fermented and cultured, the mycelial effect of gained is substantially identical with natural cordyceps, and effect is stronger.It is rich in adenosine, polysaccharide isoreactivity material, and not only rich content and ratio are suitable, effectively strengthen human body constitution, improve immunity function and anti-fatigue ability comprehensively.Peacilomyce hepiahi bacterium powder can impel the antibody-secreting amount of human body to increase, and can activate the immunocompetent cell of body, especially have obvious facilitation to lymphocyte transformation and abdominal cavity macrophage phagocytosis.
Glossy ganoderma, profile is umbrella, cap kidney shape, semicircle or subcircular, is the fructification of On Polyporaceae glossy ganoderma.There is invigorating qi for tranquilization, relieving cough and asthma effect, cough breathe heavily for dizzy egersis, palpitation, consumptive disease.
Freeze dry powder of fermented soybean contains Bacillus natto, natto polypeptide, natto polysaccharide, mucoitin, superoxide dismutase, glutathione, Nattokinase, pyridinedicarboxylic acid, lysozyme, high resiliency protease, lecithin, saponin, isoflavones, farnoquinone, vitamin E, B family vitamin, several mineral materials etc., has the physiological activator of more than 150 kinds.Can immune system be improved, improve the disease of immune system such as rheumatoid disease, lupus erythematosus, psoriasis; Impel cancer cell-apoptosis, improve polyp, hyperplasia, tumour, myomata, tumour etc.
Compendium of Material Medica: Poria cocos smell is light and ooze, and its property is up, born fluid, loosing the interspaces of skin and muscles, grows water source and declines, diuresis, therefore Zhang Jiegu calls its genus sun, floats and rises, saying its property also; Dong Yuan calls it for the YIN aspect of YANG, fall and under, Yan Qigong is also.
The Radix Astragali, nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel.Its history in medicinal existing more than 2000 year so far, it has enhanced machine body immunity function, protects the liver, diuresis, anti-ageing, resisting stress, step-down and antibacterial action more widely.
The root of bidentate achyranthes, nature and flavor: bitter, sweet, sour are flat.Gui Jing: return liver, kidney channel.Effect: stimulate the menstrual flow by the stasis of blood, filling liver kidney, strengthening the bones and muscles, inducing diuresis for treating strangurtia, ensurings proper downward flow of the blood.Cure mainly: for through closing, dysmenorrhoea, soreness of waist and knee joint, muscles and bones is unable, stranguria, oedema, headache, dizzy, toothache, day sore, spit blood, bleeding from five sense organs or subcutaneous tissue.
Radix Angelicae Sinensis, function cures mainly: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.The all cards of the main deficiency of blood; Irregular menstruation; Through closing; Dysmenorrhoea; Abdominal mass knot is poly-; Uterine bleeding; Asthenia cold abdominalgia; Impotence numbness; Numbness; Intestines are dry just difficult; Heavy after dysentery characterized by blood in the stool; Ulcer sores; Injury from falling down.
Dendrobium candidum, flavor efficacy: taste is sweet, cold nature.To promote the production of body fluid nourishing the stomach; Nourishing Yin and clearing heat; Moistening lung kidney-nourishing; The strong waist of improving eyesight.
American Ginseng, nature and flavor: cool in nature, sweet, the micro-hardship of taste.Function cures mainly: boosting qi and nourishing yin, clearing heat and promoting fluid.Lose for deficiency of vital energy the moon, interior heat, cough and breathe heavily phlegm blood, abnormal heat is tired of tired, quenches one's thirst, and the dry larynx of mouth is done.Benefit lung yin, the clear fire of deficiency type, promotes the production of body fluid to quench thirst.Control the deficiency syndrome of the lung to cough for a long time, lose blood, dry throat and mouth, abnormal heat is tired of tired.
The red sage root has promoting blood circulation, inducing meastruation to relieve menalgia, and clear away heart-fire relieving restlessness, and cool blood disappears effect of carbuncle.For chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, lump in the abdomen lump in the abdomen is gathered, hot numbness pain, dysphoria and insomnia, and irregular menstruation, dysmenorrhoea is through closing, and sore swells and ache.
Pseudo-ginseng, nature and flavor: sweet, micro-hardship, temperature.Gui Jing: return liver, stomach warp.Effect: loose stasis of blood hemostasis, detumescence ding-tong.Cure mainly: for spitting of blood, spit blood, bleeding from five sense organs or subcutaneous tissue, has blood in stool, uterine bleeding, traumatism and bleeding, chest ventral spine pain, tumbling and swelling.
The invention has the beneficial effects as follows: the present invention utilizes pure natural Chinese herbal medicine and raw-food material to be prepared into health food, this formula studies science in strict accordance with theory of traditional Chinese medical science and modern health to draft, whole reasonable recipe, rigorous, the health food of multiple formulation can be prepared into, the cause of disease of existing inferior health has been decided from human organism's Interior Solutions, fundamentally solve inferior health problem, instead of simply take stopgap measures.
The present invention selects peacilomyce hepiahi bacterium powder to replace the Cordyceps sinensis of traditional Chinese medicine, replaces expensive natural product with artificial fermentate, relaxes natural cs medicine source few, the contradiction that supply falls short of demand.The raw material that the present invention chooses is easy to get, and preparation technology is relatively simple, and cost can be controlled, and is easy to suitability for industrialized production.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described further.
Embodiment 1
A kind of health food, this health food is prepared into hard shell capsules, and its component and parts by weight are: 4 parts, peacilomyce hepiahi bacterium powder, glossy ganoderma 1.5 parts, freeze dry powder of fermented soybean 12 parts, 0.26 part, Poria cocos, the Radix Astragali 0.7 part, the root of bidentate achyranthes 0.38 part, Radix Angelicae Sinensis 1.5 parts, dendrobium candidum 0.33 part, American Ginseng 6 parts, the red sage root 0.8 part, pseudo-ginseng 1.5 parts.Glossy ganoderma, Poria cocos, the Radix Astragali, the root of bidentate achyranthes, Radix Angelicae Sinensis, dendrobium candidum, American Ginseng, the red sage root, pseudo-ginseng are mixed by weight proportion, then conveniently water extraction mode extracts twice, after merging extracted twice liquid, concentrated spray is dry, mix with the peacilomyce hepiahi bacterium powder of formula ratio, freeze dry powder of fermented soybean again, be filled in capsule shells by hard shell capsules automatic filling equipment, make hard capsule.
According to Example formulations, 1000 people try out, wherein 971 people think the present invention in raising immunity, build up health, there is significant effect in reducing blood lipid, total effective rate is 97.1%.
Embodiment 2
A kind of health food, this health food is prepared into tablet, and its component and parts by weight are: 5.6 parts, peacilomyce hepiahi bacterium powder, glossy ganoderma 2.1 parts, freeze dry powder of fermented soybean 15 parts, 0.36 part, Poria cocos, the Radix Astragali 0.78 part, the root of bidentate achyranthes 0.45 part, Radix Angelicae Sinensis 1.5 parts, dendrobium candidum 0.28 part, American Ginseng 6 parts, the red sage root 0.6 part, pseudo-ginseng 1.8 parts.Glossy ganoderma, Poria cocos, the Radix Astragali, the root of bidentate achyranthes, Radix Angelicae Sinensis, dendrobium candidum, American Ginseng, the red sage root, pseudo-ginseng are mixed by weight proportion, then conveniently water extraction mode extracts twice, after merging extracted twice liquid, concentrated spray is dry, mix with the peacilomyce hepiahi bacterium powder of formula ratio, freeze dry powder of fermented soybean again, add a certain amount of sodium carboxymethyl starch, after granulation, be pressed into plain sheet, dressing, obtains tablet.
According to Example formulations, 1000 people try out, and wherein 969 people think that the present invention has significant effect in improving immunity, building up health, and total effective rate is 96.9%.
Function test
1 materials and methods
1.1 sample copy invention products, specification 0.8g/ sheet × 40 slice/bottle, are provided by the present inventor, sample morphology be yellowish-brown to sepia tablet, sealing is put shady and cool dry place and is preserved.Sample human body RD is 3.2g/ (people d).
200 Healthy female mouse that 1.2 animal origins and point group selection are bred purchased from Shanghai western pul-Bi Kai animal used as test Co., Ltd, body weight is 19.0 ~ 21.9g.Experimental animal room temperature is 21 ~ 25 DEG C, relative humidity is 45% ~ 70%.Experimental animal is divided into 5 large group at random by body weight, often organizes 40 greatly and is divided into 4 dosage groups, each dosage group 10 mouse, and wherein first treated animal measures the mouse spleen lymphocyte conversion of ConA induction and utilizes lactic dehydrogenase enzyme process mensuration NK cytoactive; Second largest treated animal utilizes auricle edema method to carry out the delayed allergy of DNFB inducing mouse; The third-largest treated animal carries out humoral immune function detection (antibody-producting cell detects and serum hemolysin measures); The fourth-largest treated animal carries out the carbonic clearance test of monocytes/macrophages function; The fifth-largest treated animal carry out monocytes/macrophages function utilize half intracorporal method carry out peritoneal macrophage engulf chicken red blood cell test.
The human body RD that 1.3 dosage choice and tested material give mode given the test agent is 3.2 (people d) (with 60kg batheroom scale), if be equivalent to 3 dosage groups of 5 times of given the test agent human body recommended intake, 10 times, 30 times respectively, namely 0.27,0.53,1.60g/ (kgbwd).Control group is separately established to replace tested material with sterilized water, i.e. 0g/ (kgbwd).Adopt sterilized water preparation given the test agent, by high, medium and low dosage respectively compound concentration be 160,53,27mg/ml, per os gives the tested material of animal subject corresponding dosage once a day, and mouse stomach amount is 0.1ml/ (10gbw).Successive administration detects various functions index after one month.
1.4 pertinent instruments and reagent
1.4.1 instrument.Card punch, multi-functional ELIASA, CO2gas incubator, SG-603 Biohazard Safety Equipment, T1000 type electronic balance, JA2003 type electronic balance, JJ-100 type electronic balance.
1.4.2 reagent.GPS, india ink, isopropyl alcohol, Dou Shi reagent, SA buffer solution, YAC-1 cell, LDH matrix liquid, DNFB, SRBC, RPMI1640, Co-nA, MTT.
1.5 data statistics SPSS10.0 softwares carry out homogeneity test of variance to each test initial data, meet the data information that variance requires together, in use one-way analysis of variance method, between multiple test group and a control group, the comparative approach between two of mean carries out statistical disposition; Suitable variable transitions is carried out to the data information of Non-Gaussian Distribution or heterogeneity of variance, after meeting normal state or variance and requiring together, carries out statistical disposition by the data of conversion gained.
1.6 results judge that in wantonly 2, result is positive in cellular immune function (the mouse spleen lymphocyte conversion of ConA induction, DNFB inducing mouse DTH), humoral immune function (antibody-producting cell detection, serum hemolysin measure), monocytes/macrophages function (mouse carbonic clearance, Turnover of Mouse Peritoneal Macrophages engulf chicken red blood cell), NK cytoactive 4, can judge that this given the test agent has develop immunitypty effect.2 result of the tests wherein in cellular immune function assay, humoral immune function mensuration, each project of monocytes/macrophages functional examination are the positive, or 2 dosage group results of any one test are positive, can judge that this functional examination result is positive.More than one dosage group result of NK cytoactive detection test is positive, can judge that NK cytoactive result is positive.
2 results and analysis
2.1 cellular immune function tests
2.1.1 product of the present invention is on the impact of the mouse spleen lymphocyte conversion that ConA induces.After per os gives the product 30d of the present invention of mouse various dose, carry out the mouse spleen lymphocyte conversion test (mtt assay) of ConA induction, calculate the difference (add ConA hole and do not add ConA hole) of absorbance, and homogeneity test of variance is carried out to it, meet homogeneity of variance requirement, carry out statistical disposition with the comparative approach between two of mean between test group multiple in one-way analysis of variance method and a control group.1.60 (kgbwd) organize the difference (add ConA hole with do not add ConA hole) of absorbance, and, higher than 0g/ (kgbwd) group, difference has statistical significance (P<0.05).
2.1.2 product of the present invention is on the impact of DNFB inducing mouse DTH.Per os gave the product of the present invention of mouse various dose after one month, carry out DNFB inducing mouse DTH by ear swelling method to test, calculating auricular concha increases weight, and carry out homogeneity test of variance, meet after homogeneity of variance requires and carry out statistical disposition with the comparative approach between two of mean between test group multiple in one-way analysis of variance method and a control group.0.53,1.60 (kgbwd) organize auricular concha weightening finish higher than 0g/ (kgbwd) group, and difference has statistical significance (P<0.05).
2.2 ion vitro immunization function tests
2.2.1 product of the present invention is on the impact of mouse antibodies cellulation.After per os gives the product 30d of the present invention of mouse various dose, improve slide method with Jerne and carry out the test of mouse antibodies cellulation, calculate hemolysis plaque number, and carry out homogeneity test of variance, meet after homogeneity of variance requires and carry out statistical disposition with the comparative approach between two of mean between test group multiple in one-way analysis of variance method and a control group.1.60g/ (kgbwd) organizes hemolysis plaque number higher than 0g/ (kgbwd) group, and difference has statistical significance (P<0.05).
2.2.2 product of the present invention is on the impact of mice serum HD50 value.Per os gave the product of the present invention of mouse various dose after one month, measured the half hemolytic dose of mouse, and carried out homogeneity test of variance, do not meet homogeneity of variance requirement, carry out statistical disposition with rank test by HD50 value method.0.27,0.53,1.60g/ (kgbwd) organizes mice serum HD50 value (HC5.) compare with 0g/ (kgbwd) group, no significant difference (P>0.05).
2.3 monocytes/macrophages function tests
2.3.1 product of the present invention is on the impact of mouse carbonic clearance ability.Per os gave the product of the present invention of mouse various dose after one month, carry out the test of mouse carbonic clearance, calculate phagocytic index a, and carry out homogeneity test of variance, meet homogeneity of variance requirement, carry out statistical disposition with the comparative approach between two of mean between test group multiple in one-way analysis of variance method and a control group.1.60g/ (kgbwd) organizes mouse phagocytic index higher than 0g/ (kgbwd) group, and difference has statistical significance (P<0.05).
2.3.2 product of the present invention engulfs the impact of chicken red blood cell on Turnover of Mouse Peritoneal Macrophages.After per os gives the product 30d of the present invention of mouse various dose, carry out Turnover of Mouse Peritoneal Macrophages with half intracorporal method and engulf chicken red blood cell test, calculate phagocytic index and phagocytic percentage, and by phagocytic percentage through sin
-1p
1/2(P is phagocytic percentage, represents decimally) carries out homogeneity test of variance after transforming, and after meeting homogeneity of variance requirement, carries out statistical disposition with the comparative approach between two of mean between test group multiple in one-way analysis of variance method and a control group.1.60g/ (kgbwd) organizes phagocytic percentage and phagocytic index higher than 0g/ (kgbwd) group, and difference has statistical significance (P<0.05).
2.4NK cytoactive detection per os carries out NK cells in mice determination of activity, by it through sin by determination of lactate dehydrogenase method after giving the product 30d of the present invention of mouse various dose
-1p
1/2(P is NK cytoactive, represents decimally) carries out homogeneity test of variance after transforming, and meets homogeneity of variance requirement, carries out statistical disposition with the comparative approach between two of mean between test group multiple in one-way analysis of variance method and a control group.0.27,0.53,1.60 (kgbwd) organize NK cytoactive and 0 (kgbwd) group and compare, no significant difference (P>0.05).
3 brief summaries
Product of the present invention with 0.27,0.53,1.60g/ (kgbwd) gives sample 30d continuously, by " health food inspection and assessment technical specification " requirement, respectively the mouse of various dose group is carried out to the mensuration of cellular immune function, humoral immune function, monocytes/macrophages function, NK cytoactive.Found that, the cellular immune function test of product develop immunitypty function of the present invention is humoral immune function test that is positive, product develop immunitypty function of the present invention is that monocytes/macrophages function test that is negative, product develop immunitypty function of the present invention is the positive, the NK cytoactive detection test of product develop immunitypty function of the present invention is feminine gender.
Result according to the develop immunitypty function test of " health food inspection and assessment technical specification " judges, in cellular immune function (the mouse spleen lymphocyte conversion of ConA induction, DNFB inducing mouse DTH), humoral immune function (antibody-producting cell detection, serum hemolysin measure), monocytes/macrophages function (mouse carbonic clearance, Turnover of Mouse Peritoneal Macrophages engulf chicken red blood cell), NK cytoactive 4, in wantonly 2, result is positive, can judge that this given the test agent has develop immunitypty effect.Under this experimental condition, product of the present invention has develop immunitypty function.
Above to invention has been detailed introduction, the explanation of above embodiment just understands the present invention for helping.Those of ordinary skill in the art should be appreciated that to change technical scheme of the present invention, retouch or be equal to and replaces, and does not depart from the spirit and scope of technical solution of the present invention, and it all should belong in the middle of claims of the present invention.
Claims (2)
1. a health food, is characterized in that it is made up of the common hybrid process of the raw material of following portions by weight: peacilomyce hepiahi bacterium powder 2-6 part, glossy ganoderma 1-3 part, freeze dry powder of fermented soybean 8-16 part, Poria cocos 0.2-0.5 part, Radix Astragali 0.4-1 part, root of bidentate achyranthes 0.3-0.6 part, Radix Angelicae Sinensis 1-3 part, dendrobium candidum 0.2-0.4 part, American Ginseng 3-8 part, red sage root 0.5-1 part, pseudo-ginseng 1-2 part.
2. the preparation method of a health food, comprise the following steps: glossy ganoderma, Poria cocos, the Radix Astragali, the root of bidentate achyranthes, Radix Angelicae Sinensis, dendrobium candidum, American Ginseng, the red sage root, pseudo-ginseng are mixed by weight proportion, then conveniently water extraction mode extracts twice, after merging extracted twice liquid, concentrated spray is dry, mix with the peacilomyce hepiahi bacterium powder of formula ratio, freeze dry powder of fermented soybean again, add auxiliary material and obtain granule, tablet, hard capsule, soft capsule through corresponding technique.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510558745.4A CN105124578A (en) | 2015-09-06 | 2015-09-06 | Health-care food |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510558745.4A CN105124578A (en) | 2015-09-06 | 2015-09-06 | Health-care food |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105124578A true CN105124578A (en) | 2015-12-09 |
Family
ID=54710455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510558745.4A Pending CN105124578A (en) | 2015-09-06 | 2015-09-06 | Health-care food |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105124578A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110663948A (en) * | 2019-11-20 | 2020-01-10 | 江西普正制药股份有限公司 | Health product with immunity enhancing effect and preparation method thereof |
-
2015
- 2015-09-06 CN CN201510558745.4A patent/CN105124578A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110663948A (en) * | 2019-11-20 | 2020-01-10 | 江西普正制药股份有限公司 | Health product with immunity enhancing effect and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102613555B (en) | Maca powder and ginseng composition and preparation method thereof | |
CN103039668B (en) | Pueraria breast enlargement tea and preparation method thereof | |
CN101940740B (en) | Chinese medicinal preparation for treating anemia | |
CN103520368B (en) | A kind of Traditional Chinese medicine health-preserving preparation with qi and blood tonifying, enhancing immunity function | |
CN106072578A (en) | There is the enhancing enzyme composition of immune function of human body, effervescent tablet and preparation method | |
CN113318201A (en) | Health food for reducing uric acid and preparation method thereof | |
CN103099966A (en) | Stomach-invigorating and spleen-benefiting potion | |
CN102579803B (en) | Medicine for treating post-chemotherapy leucopenia and preparation method thereof | |
CN103585479A (en) | Blood-replenishing pill and blood-replenishing capsule for treating iron-deficiency anemia | |
CN105055849A (en) | Traditional Chinese medicine extract capable of nourishing Yin and tonifying kidney as well as preparation method and application of traditional Chinese medicine extract | |
CN103768434B (en) | A kind of Chinese medicine improving laying rate of laying hen and preparation method thereof | |
CN105124578A (en) | Health-care food | |
CN105920269A (en) | Health-care medicinal liquor for females | |
CN102935111B (en) | Traditional Chinese medicinal composition for enhancing human body immunity and technology for preparing traditional Chinese medicinal composition | |
CN102274346B (en) | Medicament or health food composition for preventing hypertension and preparation method and purpose thereof | |
CN102743579B (en) | Qi tonifying and blood replenishing Chinese medicinal pills and preparation process thereof | |
CN109966427A (en) | A kind of fermentation living bacterial liquid and preparation method thereof treated tumour and improve immunity of organisms | |
CN109453355A (en) | It is a kind of to prevent the high composition of pregnancy period three, drinks and preparation method thereof | |
CN104800771A (en) | Traditional Chinese medicine preparation for treating children sleep terror disorder and preparation method thereof | |
CN104189231A (en) | Traditional Chinese medicine preparation for resisting virus and enhancing immunity and preparation method thereof | |
CN114947127A (en) | Health food composition for improving immunity of tumor patients and preparation method and application thereof | |
CN107998366A (en) | It is a kind of suitable for Chinese medicine composition of puerpera's lactagogue at initial stage in postpartum and preparation method thereof | |
CN107913357B (en) | New use of a Chinese medicinal composition in preparing medicine/health product for treating asthenospermia | |
CN103055036A (en) | Method for preparing medicament for treating leucopenia | |
CN114949114B (en) | Agilawood-containing traditional Chinese medicine composition for enhancing immunity as well as preparation method, preparation and application thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
WD01 | Invention patent application deemed withdrawn after publication | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20151209 |