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CN104644298A - Direct valve loader - Google Patents

Direct valve loader Download PDF

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Publication number
CN104644298A
CN104644298A CN201310597593.XA CN201310597593A CN104644298A CN 104644298 A CN104644298 A CN 104644298A CN 201310597593 A CN201310597593 A CN 201310597593A CN 104644298 A CN104644298 A CN 104644298A
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CN
China
Prior art keywords
valve
guide member
far
compression shell
plunger
Prior art date
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Granted
Application number
CN201310597593.XA
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Chinese (zh)
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CN104644298B (en
Inventor
D·迪拉德
C·菲格
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Jieruishi Co., Ltd
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Spiration Inc
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Priority to CN201310597593.XA priority Critical patent/CN104644298B/en
Publication of CN104644298A publication Critical patent/CN104644298A/en
Application granted granted Critical
Publication of CN104644298B publication Critical patent/CN104644298B/en
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Abstract

The invention provides a valve loading system. The valve loading system uses a valve loader to transfer a valve or other medical facility from the valve loader to a deployed device. The valve can be compressed in the valve loader, so that the valve can be adapted and configured in the working channel or other cavities of the deployed device. In some embodiments, the additional valve can be loaded in the valve loader after the first valve is transferred to the deployed device.

Description

Direct valve loader
Technical field
Embodiment of the present invention relate in general to field of medical device, particularly, relate to method, system and the equipment that will load for implantation into the valve in health or support (stent) or be incorporated in endoscope or other transmission equipments.
Background technology
Transmission equipment can be to be inserted into the pipe in health, body cavity, conduit or blood vessel.Such as, transmission equipment can comprise the endoscope with a service aisle or other chambeies, and described endoscope is configured to the lung coming close to patient via the throat of patient or other air flues.Endoscope also can comprise a camera or other visual device, and endoscope is positioned in the health of patient by the user for auxiliary endoscope.Described endoscope can be commercially available bronchoscope, the BR-P180 such as manufactured by Olympus (Olympus).Bronchoscope can be used for allowing to be come close in health by surgical unit and/or implantable devices.Endoscope except bronchoscope can be used for the operation in other field, and such endoscope can be provided with a service aisle for implantable devices or other chambeies.There is provided the path entering health to allow endoscope, implantable devices must be inserted in endoscope.
Summary of the invention
Embodiment of the present invention relate in general to loader equipment, the system and method that will load for implantation into the valve in health or other armarium and/or be incorporated in transmission equipment.
In some embodiments, valve loader comprises a plunger.Described plunger can have a near-end and a far-end, and the described far-end of described plunger comprises a bonding part.In some embodiments, described valve loader comprises a guide member, and described guide member has a near-end and a far-end.Described guide member can comprise a guiding tube chamber between the described far-end of described guide member and described near-end, and described guiding tube chamber is configured to receive described plunger and allows described plunger to be advanced through described guiding tube chamber from the described near-end of described guide member through the described far-end of described guide member.Described valve loader can comprise a compression shell, and described compression shell has a near-end and a far-end, and the described near-end of described compression shell is configured to the described far-end being attached to described guide member removedly.Described compression shell can comprise a pressure channel between the described near-end of described compression shell and described far-end, and described pressure channel is configured to receive described plunger and allows described plunger to enter described pressure channel from the described near-end of described compression shell.When described compression shell is attached to described guide member removedly, described pressure channel can with described guiding tube chamber coaxial communication.Described compression shell can comprise a conical section, and the diameter of described pressure channel is reduced with the described far-end of a taper angle (convergence angle) from the described near-end of described conical section to described conical section.Described conical section can have sidewall, and described sidewall has one or more groove.Described one or more groove can extend to the distal part of described sidewall from the portions of proximal of described sidewall, described one or more groove is configured to engage with a compressible medical valve.
In some embodiments, the described plunger of described valve loader also can comprise a piston cap and a plunger rod, and described piston cap connects with the described near-end of described plunger rod.Described piston cap can have the diameter larger than the diameter of described plunger rod.In some embodiments, described equipment can comprise an elastic component, and described elastic component is between the described near-end and the described far-end of described piston cap of described guide member.Described elastic component can be configured to engage with described plunger rod.In some embodiments, described elastic component is a spring.In some embodiments, described valve loader can comprise a stopper element, and described stopper element is between the described near-end and the described far-end of described piston cap of described guide member.Described stopper element can be configured to engage releasedly with described plunger rod, and when engaging with described plunger rod, described stopper element can be prevented described plunger and move along distal direction.Described stopper element can comprise a stop release component, and described stop release component is configured to described stopper element to depart from from described plunger rod.
In some embodiments, described guide member comprises locking (locking) component, and described locking component is configured to allow described guide member to connect releasedly with described compression shell.In some embodiments, described compression shell comprises a lock fit part.Described locking component on described guide member can comprise at least one tab member, and at least one tab member described is configured to engage releasedly with the described lock fit part of described compression shell.
In some embodiments, described valve loader also comprises one or more stable (stabilizing) component, described one or more stabilizing member is configured to frictionally be combined with described stopper member, thus limits the movement at least one direction of described stopper member.At least one in described stabilizing member can be O type ring.In some embodiments, described compression shell and/or described guide member can comprise a haptic (tactile portion), and described haptic is configured to contribute to user and grasps described compression shell and/or guide member.In some embodiments, described guide member comprises at least one alternate channel (secondary channel) be separated with described guiding tube chamber.In some embodiments, described guide member comprises the screw thread (threading) on the described far-end of described guide member.Described compression shell can comprise the threaded section on the described near-end of described compression shell, and described threaded section can be configured to and being threadedly engaged on the described far-end of described guide member.In some embodiments, the taper angle at some place of described conical section is greater than the taper angle at another some place of described conical section.
One uses the described valve loader method be loaded into by valve in deployment devices (deploymentapparatus) to comprise and is loaded in described pressure channel by compressible medical valve.Described method also can comprise and being inserted in the service aisle of deployment devices by the described far-end of described valve loader.In some configurations, described method comprises the described conical section using described plunger described compressible medical valve to be forced through described pressure channel, and releases the described far-end of described valve loader.Described method also can comprise and being removed by the described service aisle of the described far-end of described valve loader from described deployment devices.
In another embodiment, valve loader comprises a plunger.Described plunger can have a near-end and a far-end, and the described far-end of described plunger comprises a bonding part.In some embodiments, described valve loader comprises a guide member, and described guide member has a near-end and a far-end.Described guide member can comprise a guiding tube chamber between the described far-end of described guide member and described near-end, and described guiding tube chamber is configured to receive described plunger and allows described plunger to be advanced through described guiding tube chamber from the described near-end of described guide member through the described far-end of described guide member.Described guide member also can comprise an external flange of the described proximate distal ends of described guide member.
Described valve loader can comprise the axle collar (collar) component, and described collar member has a near-end and a far-end, and comprises an axle collar tube chamber and an inner flange.Described inner flange can be positioned at the described near proximal ends of described collar member, and can be configured to engage with the described external flange of described guide member.
In some embodiments, described valve loader can comprise a compression shell, and described compression shell has a near-end and a far-end, and the described near-end of described compression shell is configured to the described far-end being attached to described collar member removedly.Described compression shell can comprise a pressure channel between the described near-end of described compression shell and described far-end, and described pressure channel is configured to receive described plunger and allows described plunger to enter described pressure channel from the described near-end of described compression shell.When described compression shell is attached to described guide member removedly, described pressure channel can with described axle collar tube chamber and/or described guiding tube chamber coaxial communication.Described compression shell can comprise a conical section, and the diameter of described pressure channel is reduced with the described far-end of a taper angle from the described near-end of described conical section to described conical section.Described pressure channel can be configured to receive described plunger and allow described plunger to enter described compression shell from the described near-end of described compression shell.
In some embodiments, described collar member also can comprise the screw thread on the described far-end of described collar member.Described compression shell also can comprise the threaded section on the described near-end of described compression shell, and described threaded section is configured to be threadedly engaged described on the described far-end with described collar member.In some embodiments, the described plunger of described valve loader also can comprise a piston cap and a plunger rod, and described piston cap connects with the described near-end of described plunger rod.Described piston cap can have the diameter larger than the diameter of described plunger rod.In some embodiments, described equipment can comprise an elastic component, and described elastic component is between the described near-end and the described far-end of described piston cap of described guide member.Described elastic component can be configured to engage with described plunger rod.In some embodiments, described elastic component is a spring.In some embodiments, described valve loader can comprise a stopper element, and described stopper element is between the described near-end and the described far-end of described piston cap of described guide member.Described stopper element can be configured to engage releasedly with described plunger rod, and when engaging with described plunger rod, described stopper element can be prevented described plunger and move along distal direction.Described stopper element can comprise a stop release component, and described stop release component is configured to described stopper element to depart from from described plunger rod.
In some embodiments, described valve loader also comprises one or more stabilizing member, and described one or more stabilizing member is configured to frictionally engage with described stopper member, to limit the movement of described stopper member along at least one direction.At least one in described stabilizing member can be O type ring.In some embodiments, described compression shell and/or described guide member can comprise a haptic, and described haptic is configured to contribute to user and grasps described compression shell and/or guide member.In some embodiments, described guide member comprises at least one alternate channel be separated with described guiding tube chamber.In some embodiments, the taper angle at some place of described conical section is greater than the taper angle at another some place of described conical section.
A kind ofly use the described valve loader method be loaded into by valve in deployment devices to comprise compressible medical valve is loaded in described pressure channel.Described method also can comprise and being inserted in the service aisle of deployment devices by the described far-end of described valve loader.In some configurations, described method comprises the described conical section using described plunger described compressible medical valve to be forced through described pressure channel, and releases the described far-end of described valve loader.Described method also can comprise and being removed by the described service aisle of the described far-end of described valve loader from described deployment devices.
In another embodiment, a kind ofly can comprise a compressible medical valve for the system be loaded into by medical valve in deployment devices, described compressible medical valve is configured to be inserted in the service aisle of deployment devices.In some embodiments, described system can comprise a valve loader.Described valve loader can comprise a plunger.Described plunger can have a near-end and a far-end, and the described far-end of described plunger comprises a bonding part.In some embodiments, described valve loader comprises a guide member, and described guide member has a near-end and a far-end.Described guide member can comprise a guiding tube chamber between the described far-end of described guide member and described near-end, and described guiding tube chamber is configured to receive described plunger and allows described plunger to be advanced through described guiding tube chamber from the described near-end of described guide member through the described far-end of described guide member.Described valve loader can comprise a compression shell, and described compression shell has a near-end and a far-end, and the described near-end of described compression shell is configured to the described far-end being engaged to described guide member removedly.
In some embodiments, described compression shell can comprise a pressure channel between the described near-end of described compression shell and described far-end, and described pressure channel is configured to receive described plunger and allows described plunger to enter described pressure channel from the described near-end of described compression shell.When described compression shell is attached to described guide member removedly, described pressure channel can with described guiding tube chamber coaxial communication.Described compression shell can comprise a conical section, and the diameter of described pressure channel is reduced with the described far-end of a taper angle from the described near-end of described conical section to described conical section.Described conical section can have sidewall, and described sidewall has one or more groove.Described one or more groove can from the proximal extension of described sidewall to the far-end of described sidewall, and described one or more groove is configured to engage with a compressible medical valve.
In other embodiments, method valve being loaded into deployment devices can comprise in the pressure channel be loaded into by compressible medical valve in the compression shell of valve loader, and described pressure channel has a conical section.Described valve loader can have a near-end and a far-end.Described method can comprise the guide member of described valve loader is attached to described compression shell.In some embodiments, described method comprises in the described pressure channel be inserted into by the plunger of described valve loader in described valve loader, to contact described compressible medical valve.The described far-end of described valve loader can be inserted in the service aisle of deployment devices.Described plunger can be used to the described conical section described compressible medical valve being forced through described pressure channel, and releases the described far-end of described valve loader.Described method can comprise and being removed by the described service aisle of the described far-end of described valve loader from described deployment devices.
In some embodiments, described method also comprises and carrying out disinfection to described valve loader and/or described compressible medical valve.Described method also can comprise and moves described plunger along described proximal direction, to eliminate the contact between described plunger and described compressible medical valve.Described method also comprises and being connected from described compression shell disconnection by described guide member.In some embodiments, described method can comprise and being loaded in described pressure channel by least one additional valve.
In other embodiments, a kind of method be loaded into by valve in valve loader can comprise in the pressure channel be loaded into by compressible medical valve in the compression shell of valve loader, described compression shell has a conical section, and described valve loader has a near-end and a far-end.Described method can comprise the guide member of described valve loader is attached to described compression shell, and is inserted into by the plunger of described valve loader in the described pressure channel in described valve loader.In some embodiments, described method also can comprise and being loaded in described pressure channel by least one additional valve.Described method also can comprise and carrying out disinfection to described valve loader and/or described compressible medical valve.Described method also can comprise the described valve loader of encapsulation and compressible medical valve.
Accompanying drawing explanation
For illustrative purposes, depict multiple embodiment in the accompanying drawings, these embodiments never should be interpreted as limiting the scope of the invention.In addition, the various features of disclosed different embodiments can be combined using the additional embodiment formed as a part for present disclosure.
Figure 1A diagrammatically illustrates the system for medical valve being transferred to deployment devices.
Figure 1B diagrammatically illustrates the system for medical valve being transferred to deployment devices.
Fig. 2 is the axonometric chart of an embodiment of valve loader.
Fig. 3 A is the front view of the valve loader of Fig. 2.
Fig. 3 B is the rearview of the valve loader of Fig. 2.
Fig. 4 A is the side cross-sectional, view of the valve loader of the Fig. 2 got along cutting planes 4A-4A.
Fig. 4 B is the close up view of a part for the sectional view of Fig. 4 A.
Fig. 5 is the exploded perspective view of the valve loader of Fig. 2.
Fig. 6 is the axonometric chart of an embodiment of compressible medical valve.
Fig. 7 A is the axonometric chart of an embodiment of compression shell.
Fig. 7 B is the vertical optical axis direction view of the compression shell of Fig. 7 A.
Fig. 8 A is the axonometric chart of an embodiment of guide member.
Fig. 8 B is the vertical optical axis direction view of the guide member of Fig. 8 A.
Fig. 9 A is the side elevation view of the valve loader of Fig. 2.
To be that the rear portion of the valve loader of Fig. 2 is vertical look axial view to Fig. 9 B.
To be that the front portion of the valve loader of Fig. 2 is vertical look axial view to Fig. 9 C.
Figure 10 is the axonometric chart of an embodiment of valve loader.
Figure 11 is the side view of the valve loader of Figure 10.
Figure 12 A along cutting planes 12A-12A get, the side cross-sectional, view of the valve loader of Figure 10.
Figure 12 B is the close up view of a part for the sectional view of Figure 12 A.
Figure 13 is the exploded perspective view of the valve loader of Figure 10.
Figure 14 A is used to the view of an embodiment of the valve loader loading transfer device.
Figure 14 B is used to another view of an embodiment of the valve loader loading transfer device.
Figure 14 C is used to another view of an embodiment of the valve loader loading transfer device.
Figure 14 D is used to another view of an embodiment of the valve loader loading transfer device.
Figure 14 E is used to another view of an embodiment of the valve loader loading transfer device.
Figure 15 is the side cross-sectional, view of an embodiment of valve loader, and wherein said valve loader has the medical valve being loaded into described valve loader inside.
Figure 16 is the side cross-sectional, view of an embodiment of valve loader and transfer device, and described valve loader and transfer device have medical valve therein.
Figure 17 is the side cross-sectional, view of an embodiment of valve loader and transfer device, and described transfer device has medical valve therein.
Figure 18 is the axonometric chart of an embodiment of transfer device, and described transfer device has the valve being loaded into its service aisle inside.
Figure 19 is the exploded partial perspective view of an embodiment of valve loader and medical valve.
Detailed description of the invention
Accompanying drawing referring now to one or more embodiment describes valve Load System and relevant parts.The term used in explanation given herein should not explained in any restrictive or binding mode.On the contrary, only these terms are used in combination to the specific descriptions of the embodiment of described system, method and relevant parts.In addition, embodiment can comprise multiple novel feature, any separately one in these novel features not exclusively determines the character wanting to obtain, does not also think that any separately one in these novel features is absolutely necessary for enforcement invention described here.
Term as used herein " valve ", " compressible armarium " and " armarium " are broad sense, interchangeable term; and unless otherwise directed; implication about these terms can include but not limited to: support, valve, lung air relief valve, coil (coil), filter (filter), embolus proterctive equipment, sacculus, increasing device, probe, anchor, sponge, or is configured to load or be incorporated into any other armarium in endoscope or other deployment devices (deployment apparatus), that can dispose or can not dispose.In certain embodiments, described valve and/or armarium are U.S. Patent No.s 7,533,671 or U.S. Patent No. 7,691, and type disclosed in 151, the mode that described United States Patent (USP) is quoted all is in full included in herein.
In certain embodiments, valve Load System can be configured to compress or the valve disposed of flattening bronchoscope or armarium, and the diameter of the service aisle that described bronchoscope comprises is about 1.5mm or larger (such as, about 2.6mm).In certain embodiments, described valve or armarium comprise radiopaque material, and described radiopaque material is visible by endoscope or other deployment devices, bronchoscope or health.
Term as used herein " health " and " patient " are broad sense, interchangeable term, are commonly referred to as mammals (mankind or animal) health, patient, organ, tube chamber (lumen), chamber (cavity), blood vessel, path (passageway), passage (channel) etc.
As discussed above, method described herein, system and equipment can be used valve or other armarium (can dispose or can not dispose) to be incorporated in deployment devices.In some embodiments, provide valve Load System, described valve Load System generally includes but is not limited to deployment devices, valve loader and/or miscellaneous part.After valve or other armarium are loaded in deployment devices by use valve loader, can use deployment devices that valve or other armarium are implanted or be positioned in patient body.Then, in some embodiments by using valve Load System another valve or other armarium are loaded or are incorporated in this deployment devices, this process is repeated.
Figure 1A-Figure 1B is the schematic diagram of valve Load System 3.In some embodiments, valve Load System 3 comprises valve loader 1 and deployment devices 10.Valve loader 1 can be placed as and be communicated with the service aisle fluid of deployment devices 10 or deployment devices 10 and/or be otherwise communicated with, as shown in arrow 4.Valve Load System 3 can comprise a compressible medical valve 2.Compressible medical valve 2 can be inserted in valve loader 1.In some configurations, the connecting portion 4 between valve loader and deployment devices 10 is sealed, and contacts medical valve 2 to prevent pollutant.
In some embodiments, valve loader 1 can comprise a transfer component, and described transfer component is configured to medical valve 2 to move to deployment devices 10 from valve loader 1, as shown in Figure 1B.In some configurations, transfer component comprises a plunger (plunger), and described plunger is inserted in valve loader 1, and for valve 2 being released valve loader 1 and pushing in deployment devices 10.
Fig. 2 shows the embodiment of the valve loader 100 with near-end 100A and far-end 100B.Valve loader 100 generally includes the compression shell 110 with near-end 110A and far-end 110B.In some embodiments, compression shell 110 is made up of the combination of Merlon or other similar materials or these materials.Compression shell 110 can be configured such that near-end 110A can connect removedly with guide member 130.Valve loader 100 also can comprise a plunger 180, and described plunger can be configured to be inserted in guide member 130 and/or compression shell 110.
In some configurations, the far-end 100B of valve loader 100 can have cone shape/frusto-conical, and wherein the diameter of valve loader 100 reduces from the near-end 100A of valve loader 100 to the far-end 100B of valve loader 100.In some embodiments, valve loader 100 is greater than about 1mm at the diameter at far-end 100B place and/or is less than about 3.0mm.The diameter of the reduction on the far-end 100B of valve loader 100 can help to be convenient to far-end 100B to be inserted in the service aisle of transfer device 10.
Fig. 3 A-Fig. 3 B shows an embodiment of valve loader 100, and described valve loader comprises a compression shell 110 on the far-end 100B of valve loader 100.In some embodiments, compression shell 110 comprises a cylindrical part 112 on the near-end 110A of compression shell 110, and comprises a conical portion 114 near the far-end 110B of compression shell.In some embodiments, compression shell 110 can comprise an insertion portion 116 on the far-end 110B of compression shell 110.Insertion portion 116 can have coniform shape, cylinder form or can be convenient to any other shape of being engaged with the service aisle of transfer device 10 by valve loader 100.
In some embodiments, compression shell 110 comprises one or more outside tactile feature.In some embodiments, described tactile feature can comprise flange, ridge, rough surface portion or can auxiliary valve loader 100 user grasp compression shell 110 any other feature in one or more.In the illustrative embodiment of Fig. 2-Fig. 9 C, described tactile feature comprises external flange 124.In some embodiments, external flange 124 is between the cylindrical part 112 and conical portion 114 of compression shell 110.
Fig. 4 A-Fig. 4 B shows the cross section of an embodiment of valve loader 100.As shown in the figure, compression shell 110 can comprise an internal compression passage 128.Pressure channel 128 can extend to the far-end 110B of compression shell 110 from the near-end 110A of compression shell 110.Pressure channel 128 can comprise a sidewall 144.Sidewall 144 can comprise multiple groove 126.Groove 126 can extend in the part or whole length of pressure channel 128 along sidewall 144.In some configurations, groove 126 can be substantially rectilinear, as shown in Figure 7 B.In some embodiments, groove 126 can be rectilinear.In some embodiments, groove 126 can be curved.In some embodiments, groove can be zigzag.Groove 126 can contribute to medical valve 20 to aim in pressure channel 128, as explained in detail below.In some embodiments, pressure channel 128 comprises conical section 142.The conical section 142 of pressure channel 128 can have the diameter that the far-end from the near-end of conical section 142 to conical section 142 reduces.
In some embodiments, the reduction of the diameter of conical section 142 defines a taper angle θ, and described taper angle θ is the angle between the longitudinal axis 127 and the angle of sidewall 144 of the set point place valve loader 100 of the length along pressure channel 110.Show the taper angle θ at some place in external flange distally in figure 4b.In some embodiments, the taper angle θ of the sidewall 144 of the near proximal ends of the conical section 142 of pressure channel 128 is greater than the taper angle θ of the sidewall 144 of the proximate distal ends of the conical section 142 of pressure channel 128.In some embodiments, the taper angle θ of the sidewall 144 of the proximate distal ends of the conical section 142 of pressure channel 128 is greater than the taper angle θ of the sidewall 144 of the near proximal ends of the conical section 142 of pressure channel 128.In some embodiments, the sidewall 144 of conical section 142 has a limited number of discrete taper angle, and in some embodiments, the taper angle of sidewall 144 changes continuously along the length of conical section 142.In some embodiments, the scope along the taper angle of the length of the conical section 142 of pressure channel 128 changes between about 0 ° and about 45 °.In some embodiments, taper angle changes between about 0 ° and 10 °, or changes between about 3 ° and about 20 °.In addition, in some embodiments, compression shell 110 can comprise the aperture, distally 118 on the far-end 110B of compression shell 110.Aperture, distally 118 can have circular shape, and can have the diameter being greater than about 1.0mm and/or being less than about 3.0mm.
As shown in Figure 5, valve loader 100 can comprise a guide member 130.Guide member 130 can comprise a main part 134.In some embodiments, main part 134 is substantially cylindricals.In some embodiments, guide member 130 is made up of Acrylonitrile-butadiene-styrene Copolymer (acrylonitrile butadiene styrene, ABS), but can use other similar materials.Guide member 130 can comprise a grip.In some embodiments, described grip can comprise flange, ridge, rough surface portion or can auxiliary valve loader 100 user grasp guide member 130 any other feature in one or more.In the embodiment illustrated in fig. 5, described grip comprises an external flange 132.Guide member 130 can comprise a guiding tube chamber 138, as shown in Fig. 8 A-Fig. 8 B.Guiding tube chamber 138 can run through guide member 130 from the proximal extension of guide member to the far-end of guide member.In some embodiments, guide tube chamber 138 and there is cylindrical cross-section.The diameter in the cross section of guiding tube chamber 138 can be greater than about 1.0mm and/or be less than about 3.0mm.In addition, in some embodiments, guide member 130 can comprise one or more alternate channel 140.In some configurations, described one or more alternate channel 140 runs through guide member 130 from the proximal extension of guide member 130 to the far-end of guide member 130.In some embodiments, described one or more alternate channel extends only through a part for the length of guide member 130.In some configurations, when guide member 130 is attached to compression shell 110, described one or more alternate channel 140 is configured to be communicated with pressure channel 128 fluid and/or be otherwise communicated with.
In some embodiments, guide member 130 comprises a locking component.Described locking component can be configured to allow guide member 130 for good and all and/or to be removedly attached to compression shell 110.In some embodiments, described locking component can comprise binding agent, screw thread (threading), high friction surface, mechanical latches, magnet, or can be convenient to other features a certain of the connection between compression shell 110 and guide member 130.In some embodiments, described locking component is included in the one or more lock tab 136 on the end of one or more flexible arm 147, and described one or more flexible arm is attached to the main part 134 of guide member 130.In some embodiments, compression shell 110 can comprise a lock fit part, and described lock fit part is configured to engage with the locking component of guide member 130 (such as, lock tab 136).In some embodiments, described lock fit part can comprise binding agent, screw thread, high friction surface, mechanical latches, chamber or hole, magnet, or can be convenient to other features a certain of the connection between compression shell 110 and guide member 130.In some embodiments, lock fit part comprises one or more lock bore 122 and/or one or more locking channel 123.In some embodiments, lock tab 137 is configured to engage with lock bore 122 and/or locking channel 123, thus is convenient to the removable connection between guide member 130 and compression shell 110.In some embodiments, when guide member 130 connects releasedly with compression shell 110, external flange 132 can limit the degree of depth that guide member 130 inserts the pressure channel 128 of compression shell 110.
As shown in Figure 5, an embodiment of valve loader 100 can comprise the plunger 180 with near-end 180A and far-end 180B.Plunger 180 can comprise the cap 184 on the near-end 180B of plunger 180.Cap 184 can be connected to plunger rod 182 at junction point 186 place.In some embodiments, cap 184 and plunger rod 182 are integrated parts.Cap 184 and/or plunger rod can be made up of the combination of ABS or other similar materials or material.Plunger rod 182 can have the substantially cylindrical shape that diameter is greater than about 1.0mm and/or is less than about 3.0mm.
In some embodiments, plunger 180 comprises the bonding part 188 on the far-end 180B of plunger 180.Bonding part 188 can be connected to plunger rod 182 at junction point 190 place.In some embodiments, bonding part 188 and plunger rod 182 are integrated parts.In some embodiments, bonding part 188 is made up of the combination of 304 rustless steels or other similar materials or material.Bonding part 188 can have the substantially cylindrical shape that diameter is greater than about 0.25mm and/or is less than about 3mm.
According to some configurations, valve loader 100 comprises one or more stabilizing member.In some embodiments, described stabilizing member can comprise an O type ring 106, as shown in figs. 4 a and 5.As a supplement or substitute, described stabilizing member can comprise a cylindrical collar 108.As shown in Figure 4 A, the outer dia that O type ring 106 and/or cylindrical collar 108 have can be dimensioned, to fit in the inner chamber of guide member 130 and/or compression shell 110.In some embodiments, one in O type ring 106 and cylindrical collar 108 is dimensioned, and to fit in guide member 130, another in O type ring 106 and cylindrical collar is dimensioned, to fit in compression shell 110.In addition, the inside diameter of O type ring 106 and/or cylindrical collar 108 can be dimensioned, thus engages with plunger rod 182 and/or bonding part 188 when plunger 180 is inserted in guide member 130 and/or compression shell 110.In some embodiments, the inside diameter of O type ring 106 and/or cylindrical collar 108 is greater than about 1.0mm and/or is less than about 3.0mm.In some configurations, guide member 130 comprises stable cover (stabilizingpocket) 139, and described stable cover is configured to receive O type ring 106 and/or cylindrical collar 108.In some embodiments, plunger can comprise one or more surface character that can engage with one or more stabilizing member.Such as, as shown in figs. 4 a and 5, plunger can comprise an annular notch 192, and described annular notch is configured to engage with O type ring 106.In some embodiments, the joint between annular notch 192 and O type ring 106 when the user of valve loader 100 does not input, can be prevented plunger 180 and moves along distal direction or proximal direction.
In some embodiments, valve loader 100 comprises an elastic component 160.Elastic component 160 can be positioned between piston cap 184 and guide member 130, and in some embodiments, can engage with plunger rod 182.In some embodiments, elastic component 160 is configured such that to compress when plunger 180 is pushed within guide member 130 and/or compression shell 110 along distal direction.Elastic component 160 can be configured to make when elastic component 160 is compressed along proximal direction biased piston 180.In some embodiments, elastic component 160 comprises spring (as shown in Figure 5), flexible pipe, magnet, or when biasing member 160 can be formed other suitable features of bias force on plunger 180 along proximal direction during compression.
In some configurations, valve loader 100 can comprise a stopper element 150.Stopper element 150 can be configured to engage removedly with plunger rod 182.Stopper element 150 can be positioned between piston cap 184 and guide member 130.Stopper element 150 can be made up of rigid material or semi-rigid material.When engaging with plunger rod 182, stopper element 150 can be prevented piston cap 184 and move along distal direction.In some embodiments, stopper element 150 comprises a bar bonding part 156, and described bar bonding part is configured to engage with plunger rod 182.Stopper element 150 can comprise expansion (expanded) part 158.In some embodiments, on the expansion 158 of stopper element 150 far-end that can be positioned at stopper element 150 and/or near-end.Described expansion 158 can be configured to engage with elastic component 160, and can prevent elastic component 160 and move by stopper element 150 along the length of plunger rod 182.In some embodiments, stopper element 150 can comprise one or more stop release portion 152.Described one or more stop release portion 152 can be configured such that and be easier to stopper element 150 is departed from from plunger rod 182.Such as, stop release portion 152 can comprise fin (as shown in Figure 5), radial projection, or other will the user of auxiliary valve loader 100 feature that stopper element 150 is removed from plunger rod 182.In some embodiments, on stop release portion 152 far-end that is positioned at stopper element 150 and/or near-end.In some embodiments, stop release portion 152 can be configured to engage with elastic component 160, and can prevent elastic component 160 and move by stopper element 150 along the length of plunger rod 182.
As shown in Fig. 5-Fig. 6, compressible medical valve 20 can be inserted in valve loader 100.In some embodiments, compression shell 110 is configured to receive and/or maintenance medical valve 20.In some configurations, medical valve 20 comprises a valve portion 22, and described valve portion can be connected to hub (hub) 26.Valve 20 can comprise the bar part 28 being connected to hub 26.In some embodiments, medical valve 20 can comprise an anchor portion 24.In some embodiments, anchor portion 24 comprises one or more articulated jib 36, and described one or more articulated jib can be attached to hub 26.In addition, anchor portion 24 can comprise anchoring point (anchortip) 38 on the end of articulated jib 36.Anchoring point 38 can comprise the end (sharpened ends) of sharpening.In some embodiments, articulated jib 36 comprises grappling pad 43(anchor pad).Grappling pad 43 can comprise the end (blunted ends) of passivation.In some embodiments, articulated jib 36 can be biased away from the central axis 127 of pressure channel 128 outwardly, as shown in Figure 5 and Figure 6.
In some embodiments, the valve portion 22 of medical valve 20 can comprise multiple rib 34, and described multiple rib is connected to hub 26 on the side relative with anchor portion 24 of hub 26.In some embodiments, valve portion 22 comprises a umbrella part 32, and described umbrella part is attached to described multiple rib 34.The summit of umbrella part 32 can be connected to hub 26.In some embodiments, umbrella part 32 is attached to the outside (as shown in Figure 6) of described multiple rib 34.In addition, in some embodiments, umbrella part 32 is attached to the inner side of described multiple rib 34.In some embodiments, described multiple rib 34 can be biased outwardly from the central axis of valve 20, makes umbrella part be biased to expanded configuration, as shown in Figure 5 and Figure 6.
The hub 26 of medical valve 20 can comprise a composition surface 27.Composition surface 27 can be configured to engage releasedly with the bonding part 188 of plunger 180.Such as, composition surface 27 can be configured to have identical with the cross sectional shape of the far-end of bonding part 188 or akin shape.
Figure 10-Figure 13 shows another embodiment of valve loader 200, and described valve loader comprises compression shell 210, guide member 230 and plunger 280.Some reference numbers of parts in Figure 10-Figure 13 with those previously for valve loader 100 identical or close with the reference number described by corresponding compression shell 110, guide member 130 and plunger 180 (such as, plunger 280 is relative to plunger 180).Should be understood that these parts can be functionally identical or be functionally similar to previously described parts.The valve loader 200 of Figure 10-Figure 13 shows some modification of the valve loader 100 of Fig. 2-Fig. 9 C.
In some embodiments, valve loader 200 can comprise an axle collar 270, as shown in Figure 10-Figure 13.The axle collar 270 can comprise an axle collar tube chamber 272.The axle collar 270 can comprise a guiding coupling part 276 on the near-end of the axle collar 270.In some embodiments, guide coupling part 276 can comprise inner flange (as illustrated in fig. 12), screw thread, high friction surface, binding agent and/or be suitable for being convenient to other features a certain of the discharged connection between the axle collar 270 and guide member 230.In some embodiments, guide member 230 comprises a locking component.Described locking component can be configured to allow guide member 230 forever and/or to be removedly attached to the axle collar 270 and/or compression shell 210.In some embodiments, locking component can comprise binding agent, screw thread, high friction surface, mechanical latches, magnet, or can be convenient to other features a certain of the connection between guide member 230 and the axle collar 270 and/or compression shell 210.In some embodiments, locking component comprises one or more annular ridge 236.In some embodiments, annular ridge 236 is positioned at the proximate distal ends of guide member 230.Annular ridge 236 can be sized to the inside diameter making its diameter be greater than guiding coupling part 276, and is less than the diameter of axle collar tube chamber 272.In such an arrangement, the far-end can preventing guide member 230 shifts out the axle collar 270 along proximal direction.In some embodiments, guide member 230 comprises a little flange 232 nearby at annular ridge 236.Little flange 232 can be configured to prevent guide member 230 and shift out the axle collar 270 along distal direction.
In some embodiments, the axle collar 270 comprises the compression coupling part 277 on the far-end of the axle collar 270.Compression coupling part 277 can comprise inner flange, screw thread, high friction surface, binding agent, and/or is suitable for other features a certain being convenient to the discharged connection between the axle collar 270 and compression shell 210.In some embodiments, compression shell 210 can comprise a mating part, and described mating part is configured to engage with the compression coupling part 277 of the axle collar 270.In some embodiments, described mating part can comprise binding agent, screw thread, high friction surface, mechanical latches, chamber or hole, magnet, or can be convenient to other features a certain of the connection between compression shell 210 and the axle collar 270.In some embodiments, the near-end 210A that the connection between compression shell 210 and the axle collar 270 can be convenient to compression shell 210 moves in axle collar tube chamber 272.In some embodiments, when compression shell 210 connects with the axle collar 270, the near-end 210A of compression shell 210 can with the distal contact of guide member 230.In some embodiments, annular ridge 236 can be fixed between the near-end 210A of compression shell 210 and guiding coupling part 276.In some embodiments, the near-end 210A of compression shell 210 is configured to connect with the far-end of the axle collar 270 and guide member 230.
Compression shell 210 can comprise the pressure channel 228 that has conical section 242.Pressure channel 228 can limit the sidewall 244 on the inside of compression shell 210.In some embodiments, sidewall 244 can have one or more taper angle θ 1, θ 2, and the diameter of the conical section 242 of pressure channel is reduced from the near-end of conical section 242 to the far-end of conical section 242.
Valve 20 to be loaded into method in deployment devices 10 exemplified with using valve loader 300 by Figure 14 A-Figure 14 E.Some reference numbers of parts in Figure 14 A-Figure 14 E with those previously for the reference number described by valve loader 100 identical or close (such as, compression shell 310 is relative to compression shell 110).Should be understood that these parts and previously described parts are functionally identical or be functionally similar to.The valve loader 300 of Figure 14 A-Figure 14 E shows some modification of the valve loader of Fig. 2-Fig. 9 C.
In some embodiments, deployment devices 10 can comprise endoscope, bronchoscope, or has other equipment a certain in inner passage or the chamber wherein can inserting medical valve.In some embodiments, valve 20 method be loaded in transfer device 10 is comprised the far-end 310B of compression shell 310 is positioned in the service aisle of deployment devices 10.The method also can comprise use thumb 7 or plunger 380 promotes along distal direction towards guide member 330, as shown in Figure 14 A-Figure 14 B by other modes.Plunger 380 can cause the bonding part 388 of plunger 380 to promote the far-end 310B of valve 20 towards compression shell 310 along distal direction towards the movement of guide member 330, and valve 20 is released compression shell 310 enters deployment devices 10.After valve 20 is inserted into deployment devices 10, piston cap 384 can pull away from guide member 330 by user, causes plunger 380 to move along proximal direction, as shown in Figure 14 C-Figure 14 D.The bonding part 388 that can contribute to plunger 380 away from guide member 330 piston cap 384 is pulled to depart from from valve 20.In some embodiments, valve loader 300 comprises an elastic component 360(such as, spring), when plunger 380 moves along distal direction, described elastic component can be compressed.Elastic component 360 can along proximal direction biased piston 380, and person capable of reducing using manually pulls piston cap 384 away from the needs of guide member 330.The method makes valve loader 300 move away from deployment devices 10, as shown in fig. 14e after also can being included in and being loaded in deployment devices 10 by valve 20.
Figure 15-Figure 17 shows the method be loaded into by medical valve 20 in the service aisle 12 of transfer device 10.As shown in figure 15, valve 20 can be loaded directly in the compression shell 110 of valve loader 100.In some embodiments, when not using sleeve (cartridge) or other preloaded devices, valve can be loaded directly in valve loader 100.The taper angle θ of the conical section 142 of pressure channel 128 can cause the some parts of valve 20 (such as, valve portion 22) to compress towards the central axis 127 of pressure channel 128, as shown in Figure 15 and Figure 16.In some embodiments, pressure channel 128 can comprise one or more groove 126 as discussed above.In some embodiments, when valve 20 is compressed in pressure channel 128, the groove 126 in the conical section 142 of pressure channel 128 can contribute to aiming at valve 20.In some embodiments, when valve portion 22 in the conical section 142 of pressure channel 128 by compression time, groove 126 can contribute to reducing the rib 34 of valve portion 22 and to overlap each other the probability of (such as, intersecting).Such as, one or more groove 126 can engage with one or more rib 34.Such joint can contribute to reducing one or more rib 34 and move towards the probability of another in rib 34 around the central axis 127 of compression shell 110.The advantage reducing the overlapping of rib 34 or intersection between compression period is that this can allow valve 20 spread during disposing, and contributes to the probability reducing damage threshold 20 and/or umbrella part 32 when valve 20 is expanded and/or disposed.In some embodiments, the overlapping or intersection of minimizing rib 34 can reduce the probability of the winding between the far-end of rib 34.
As shown in figure 16, when valve 20 is loaded onto in valve loader 100, plunger 180 can move along distal direction.Along with plunger 180 moves along distal direction, the bonding part 188 of plunger can engage with the hub 26 of medical valve 20, and can promote valve 20 along distal direction.Along with medical valve 20 is pushed along distal direction, the taper angle θ of the conical section 142 of pressure channel 128 can cause valve anchor portion 24 and/or valve portion 22 to compress.Along with valve anchor portion 24 compresses, the articulated jib 36 of anchor portion 24 is aimed at the central axis 127 of pressure channel 128, as shown in figure 16.The compression of valve portion 22 and the compression of articulated jib 26 are to reducing the area of section of valve 20 in the plane of the axis 127 perpendicular to pressure channel 128.The compression of valve 20 can allow valve 20 to fit within the service aisle 12 of deployment devices 10, as shown in figure 17.In the aperture, distally 118 valve 20 being forced through valve loader 110 and after entering deployment devices 10, the bonding part 188 of plunger 180 can be recalled from the hub 26 of valve 20.Bonding part 188 can be dimensioned, and makes it enough thick thus valve 20 is forced through pressure channel 128, and it is enough thin thus when bonding part 188 is pulled away from preventing during valve 20 by joint between the articulated jib 36 that compresses and bonding part 188 simultaneously.
Figure 18 shows in the service aisle 12 of transfer device 10 by the valve 20 compressed.In some embodiments, transfer device can comprise a camera 14 and/or one or more align member 16.When in service aisle 12 by compression time, the direction of the axis of anchoring point 38 can be configured to " point to (point) " passage, valve 20 is compressed in described passage.In some embodiments, grappling pad 40 can be configured to outside the orientation of its axis of passage, and valve 20 is compressed in described passage.In some configurations, the above-described orientation by the valve 20 compressed can contribute to when valve is prevented the wall that anchoring point 38 damages service aisle 12 in service aisle 12 during compression.
In some embodiments, valve loader 100 can be loaded with valve 20 by prepackage, afterwards valve loader 100 is passed to the other-end user of doctor or valve loader 100, as shown in figure 15.In some configurations, the valve loader 100 of preloaded can be configured to, for loading single valve 20, be abandoned by valve loader 100 afterwards.The above-mentioned configuration of the preloaded valve loader 100 that single uses can use ethylene oxide gas or other sterilization methods a certain to sterilize, then packed for passing to doctor or other-end user.
In some embodiments, valve loader 200 can be pre-installed and be loaded with valve 20, afterwards valve loader 200 is passed to the other-end user of doctor or valve loader 200, as illustrated in fig. 12.In some embodiments, valve loader 200 can be passed to the other-end user of doctor or valve loader 200 with unassembled state.In some configurations, valve loader 200 can be arranged to and dispose multiple valve 20.Such as, a valve can be loaded within compression shell 210 by the user of valve loader 200, and disposes valve 20 in deployment devices 10.Then, compression shell 210 can disconnect with the axle collar 270 and connecting by user, and within the compression shell 210 another valve 20 being loaded into valve loader, as shown in figure 19.Need user to use the task how many times of valve loader 200, just this process of disposing valve 20 and valve loader 200 of reloading is repeated how many times.
Otherwise understand unless specifically stated otherwise or in used context, conditional language such as comprises " can (can) ", " may (could) ", " may (might) " or " can (may) " be intended to pass on usually: some embodiment comprises some feature, element and/or step, and other embodiments do not comprise some feature, element and/or step.Therefore, such conditional language does not mean that following meaning in secret usually: in any case one or more embodiment all needs these features, element and/or step, or one or more embodiment must comprise logic for determining (when having or do not have user's input or prompting) and whether these features, element and/or step to be included in any specific embodiments or whether being performed in what specific embodiments in office.Title used herein, only for helping reader, is not intended to the scope of restriction the present invention or claim.
Although there have been described herein some embodiment and embodiment, but those of ordinary skill in the art should understand, many aspects of the shown method and apparatus with describing of present disclosure differentially can be combined and/or are revised, to form other embodiments.In addition, the disclosure of any specific features, aspect, method, character, characteristic, quality, attribute, element etc. that are associated with an embodiment of this paper can be used in the every other embodiment stated herein.In addition, will recognize, any equipment being suitable for performing the step quoted can be used to carry out method described herein.The use of such alternate embodiment and/or said method and equipment and their obvious amendment and equivalent are intended in the scope of present disclosure.

Claims (21)

1., for medical valve being loaded into the equipment in deployment devices, described equipment comprises:
A plunger, has a near-end and a far-end, and the described far-end of described plunger comprises a bonding part;
A guide member, there is a near-end and a far-end, described guide member comprises a guiding tube chamber between the described far-end and described near-end of described guide member, and described guiding tube chamber is configured to receive described plunger and allows described plunger to be advanced through described guiding tube chamber from the described near-end of described guide member through the described far-end of described guide member; And
A compression shell, there is a near-end and a far-end, the described near-end of described compression shell is configured to the described far-end being attached to described guide member removedly, described compression shell has a pressure channel between the described near-end and described far-end of described compression shell, described pressure channel is configured to receive described plunger and allows described plunger to enter described pressure channel from the described near-end of described compression shell, described pressure channel and described guiding tube chamber coaxial communication when described compression shell is attached to described guide member removedly, described pressure channel has a conical section for compressing described medical valve, the diameter of described pressure channel is reduced from the near-end of described conical section to the far-end of described conical section with a taper angle, described conical section has sidewall, described sidewall has one or more groove, described one or more groove extends to the distal part of described sidewall from the portions of proximal of described sidewall, described one or more groove is configured to engage with medical valve.
2. equipment according to claim 1, wherein said one or more groove is configured to engage with one or more ribs of described medical valve, thus prevents described one or more rib from intersecting.
3. equipment according to claim 1, wherein said compression shell is configured to not use sleeve or other preloaded equipment and directly receives medical valve from user.
4. equipment according to claim 1, wherein said equipment also comprises an axle collar, the described axle collar has one or more bonding part, described one or more bonding part is configured to engage with the described distal engagement of described guide member and/or with the described near-end of described compression shell, the described axle collar has an interior lumen, when the described axle collar engages with described compression shell and/or described guide member, described interior lumen is communicated with described compression shell and/or described guide member coaxial flow.
5. equipment according to claim 1, wherein said plunger also comprises a piston cap and a plunger rod, and described piston cap connects with the described near-end of described plunger rod, and described piston cap also has the diameter larger than the diameter of described plunger rod.
6. equipment according to claim 5, wherein said equipment also comprises an elastic component, described elastic component is between the described near-end and the described far-end of described piston cap of described guide member, and described elastic component is configured to engage with described plunger rod.
7. equipment according to claim 5, wherein said equipment also comprises a stopper element, described stopper element is between the described near-end and the described far-end of described piston cap of described guide member, described stopper element is configured to engage releasedly with described plunger rod, and is configured to prevent described plunger when engaging with described plunger rod and moves along distal direction.
8. equipment according to claim 1, wherein said guide member also comprises a locking component, and described locking component is configured to allow described guide member to connect removedly with the lock fit part of described compression shell.
9. equipment according to claim 1, wherein said equipment also comprises one or more stabilizing member, described one or more stabilizing member is configured to frictionally engage with described stopper member, to limit the movement of described stopper member along at least one direction, at least one in wherein said one or more stabilizing member is O type ring.
10. equipment according to claim 1, wherein said compression shell also comprises a haptic, and described haptic is configured to auxiliary user and grasps described compression shell.
11. equipment according to claim 1, at least one in wherein said guide member and described compression shell also comprises a haptic, and described haptic is configured at least one that auxiliary user grasps in described guide member and described compression shell.
12. equipment according to claim 1, wherein said guide member also comprises the screw thread on the described far-end of described guide member.
13. equipment according to claim 12, wherein said compression shell also comprises the threaded section on the described near-end of described compression shell, and described threaded section is configured to and being threadedly engaged on the described far-end of described guide member.
14. equipment according to claim 1, the taper angle at some place of wherein said conical section is greater than the taper angle at another some place of described conical section.
Valve to be loaded into the method in deployment devices by 15. 1 kinds, and described method comprises:
A medical valve is loaded in the pressure channel of the equipment of claim 1;
The described far-end of described valve loader is inserted in the service aisle of deployment devices;
Use described plunger described medical valve to be forced through the described conical section of described pressure channel, and release the described far-end of described valve loader; And
The described service aisle of the described far-end of described valve loader from described deployment devices is removed.
16. 1 kinds for medical valve being loaded into the system in deployment devices, described system comprises:
A medical valve, is configured to be inserted in the service aisle of deployment devices; And
A valve loader, has
A plunger, has a near-end and a far-end, and the described far-end of described plunger comprises a bonding part;
A guide member, there is a near-end and a far-end, described guide member comprises a guiding tube chamber between the described far-end and described near-end of described guide member, and described guiding tube chamber is configured to receive described plunger and allows described plunger to be advanced through described guiding tube chamber from the described near-end of described guide member through the described far-end of described guide member; And
A compression shell, there is a near-end and a far-end, the described near-end of described compression shell is configured to the described far-end being attached to described guide member removedly, described compression shell has a pressure channel between the described near-end and described far-end of described compression shell, described pressure channel is configured to receive described plunger and allows described plunger to enter described pressure channel from the described near-end of described compression shell, described pressure channel has a conical section, the described far-end of the diameter of described pressure channel from the described near-end of described conical section to described conical section is reduced, described pressure channel and described guiding tube chamber coaxial communication when described compression shell is attached to described guide member removedly, described conical section has sidewall, described sidewall has one or more groove, described one or more groove extends to the distal part of described conduit wall from the portions of proximal of described tapered wall, described one or more groove is configured to engage with a medical valve.
Valve to be loaded into the method in deployment devices by 17. 1 kinds, and described method comprises:
Be loaded into by medical valve in the pressure channel in the compression shell of valve loader, described pressure channel has a conical section, and described conical section has sidewall, and described sidewall has at least one groove, and described valve loader has a near-end and a far-end;
The guide member of described valve loader is attached to described compression shell;
The plunger of described valve loader is inserted in the described pressure channel in described valve loader, to contact described medical valve;
The described far-end of described valve loader is inserted in the service aisle of deployment devices;
Use described plunger described medical valve to be forced through the described conical section of described pressure channel, and release the described far-end of described valve loader; And
The described service aisle of the described far-end of described valve loader from described deployment devices is removed.
18. methods according to claim 17, wherein said method also comprises and moves described plunger along described proximal direction, to eliminate the contact between described plunger and described medical valve.
19. methods according to claim 17, wherein said method also comprises and being connected from described compression shell disconnection by described guide member.
20. methods according to claim 17, wherein said method also comprises and being loaded in described pressure channel by least one additional medical valve.
21. methods according to claim 17, wherein said method also comprises at least one sterilization in described valve loader and described medical valve.
CN201310597593.XA 2013-11-22 2013-11-22 Direct valve loader Active CN104644298B (en)

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