CN104413031B - A kind of compound pesticide composition of fluorine-containing ether bacterium amide - Google Patents
A kind of compound pesticide composition of fluorine-containing ether bacterium amide Download PDFInfo
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Abstract
The invention discloses a kind of compound pesticide composition of fluorine-containing ether bacterium amide, effective active composition is active components A and active constituent B, and active components A is selected from fluorine ether bacterium amide, and active constituent B is selected from any one following compound：Cymoxanil, Propamocarb, propamocarb, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb, and active components A and the weight ratio of active constituent B are 1: 80~60: 1.The present composition has greater activity to the multiple diseases in various crop, and has apparent synergistic effect, expands fungicidal spectrum.And small, resistance of rainwater washing against, the apparent feature of synergy with dosage.
Description
Technical field
The invention belongs to technical field of pesticide, it is related to a kind of compound pesticide composition of fluorine-containing ether bacterium amide in crop disease
On application.
Technical background
Fluorine ether bacterium amide (LH-2010A) selective fungicide fluopicolide more similar than structure has wider array of fungicidal spectrum.
Fluorine ether bacterium amide is to the bacteriostatic activity highest of cotton standing dead rhizoctonia and botrytis cinerea, to Phytophthora capsici and potato late blight
Germ has higher antibacterial work, and fluorine ether bacterium amide is apparent to cotton standing dead rhizoctonia bacteriostasis, can significantly inhibit its sclerotium
Generation and mycelium morphology factor, make mycelia branch increase, shorten, is thicker；Fluorine ether bacterium amide has various plants pathogen higher
Bacteriostatic activity, and can obviously inhibit the multinomial physical signs of cotton standing dead rhizoctonia.
In the real process of agricultural production, the problem of controlling disease most easily produces is the generation of disease drug resistance.No
It is compounded with kind ingredient, is to prevent the very common method of resistance disease.Heterogeneity is compounded, and is imitated according to practical application
Fruit, to judge that certain compounding is synergy, adduction or antagonism.In most cases, the compounding effect of pesticide is all to add
And effect, really have the compounding of synergistic effect seldom, especially synergistic effect clearly, the very high compounding of synergy ratio just more
It is few.Studied by inventor, find by fluorine ether bacterium amide and cymoxanil, Propamocarb, propamocarb, phosethyl-Al,
Fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb mutually compound, and have good synergistic effect in a certain range, and
In relation to fluorine ether bacterium amide and cymoxanil, Propamocarb, phosethyl-Al, pyrimorph, fluorine thiazole pyrrole ethyl ketone, phenyl ether methyl cyclic, activation
The related compounding of ester or iprovalicarb, at present at home and abroad there is not yet relevant report.
Invention content
There is synergistic function, the fluorine-containing ether bacterium acyl that use cost is low, preventive effect is good the purpose of the present invention is to propose to a kind of
The compound pesticide composition of amine.
The present invention is achieved through the following technical solutions：
A kind of compound pesticide composition of fluorine-containing ether bacterium amide, containing active components A and active constituent B, active components A with
Active constituent B weight ratios are 1: 80~60: 1, and the active components A is selected from fluorine ether bacterium amide, and active constituent B is selected from white urea
One in cyanogen, Propamocarb, propamocarb, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb
Kind；The weight ratio of preferably active components A and active constituent B is 1: 60~40: 1；More preferably fluorine ether bacterium amide and cymoxanil
Weight ratio be 1: 20~10: 1, the weight ratio of fluorine ether bacterium amide and Propamocarb is 1: 30~10: 1, fluorine ether bacterium amide and downy mildew
The weight ratio of prestige hydrochloride is 1: 30~10: 1, and the weight ratio of fluorine ether bacterium amide and phosethyl-Al is 1: 30~10: 1, fluorine ether
The weight ratio of bacterium amide and fluorine thiazole pyrrole ethyl ketone is 1: 20~10: 1, the weight ratio of fluorine ether bacterium amide and pyrimorph is 1: 20~
10: 1, the weight ratio of fluorine ether bacterium amide and Acibenzolar is 1: 10~20: 1, and the weight ratio of fluorine ether bacterium amide and iprovalicarb is 1: 20
~10: 1；Most preferably the weight ratio of fluorine ether bacterium amide and cymoxanil is 1: 9~4: 1, the weight of fluorine ether bacterium amide and Propamocarb
Than being 1: 19~1: 1, the weight ratio of fluorine ether bacterium amide and propamocarb is 1: 19~1: 1, fluorine ether bacterium amide and triethylphosphine
The weight ratio of sour aluminium is 1: 19~1: 1, and the weight ratio of fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone is 1: 9~4: 1, fluorine ether bacterium amide
Weight ratio with pyrimorph is 1: 14~4: 1, and the weight ratio of fluorine ether bacterium amide and Acibenzolar is 1: 4~9: 1, fluorine ether bacterium amide
Weight ratio with iprovalicarb is 1: 9~4: 1.
The bactericidal composition of the present invention, can be processed into acceptable dosage form in any sterilization, wherein more preferably on demand
Dosage form be that wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, micro-capsule are outstanding
Floating-suspending agent, can also be made seed coat agent, suspension seed-coating agent, granule, ultra low volume liquids.
The compound pesticide composition of the fluorine-containing ether bacterium amide is used to prevent the disease of crop；The crop is grain
Crop, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop, hobby crop, rhizome
Class crop, oil crops, flower crop, medicinal crop, crop, green manure pasture crop；The disease is downy mildew, frost
Phytophthora root rot, epidemic disease, balck shank, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker.
The amount of application when content of active constituent depends on being used alone in the bactericidal composition of the present invention, also depends on one
The mixed ratio and synergistic effect degree of kind compound and another compound, at the same it is also related with target disease.Usual group
The weight percentage for closing active constituent in object is the 1%~90% of total weight, preferably 5%~80%.According to different
Preparation type, active component content range are different.Liquids in general preparation contains by weight 1%~60% active matter
Matter, preferably 5%~50%；Solid pharmaceutical preparation contains by weight 5%~80% active material, preferably 10%~
80%.
The present invention bactericidal composition at least contain a kind of surfactant, in favor of application when active component in water
Dispersion.Surface-active contents are the 2%~30% of total formulation weight, and surplus is solid or liquid diluent.
The bactericidal composition of the present invention can used before through dilution or directly by user.Its preparation can be by ability
Prepared by the processing method well known to field technique personnel, i.e., after mixing active constituent with liquid flux or solid carrier, add
One or more of surfactant such as dispersant, stabilizer, wetting agent, binder, disintegrant, antifoaming agent etc..According to not
Same dosage form can also contain antifreeze known in those skilled in the art etc. in preparation.
Composition includes following component and content when wettable powder is made：Active components A 0.5%~60%, activity at
Divide B0.5%~80%, dispersant 1%~12%, wetting agent 1%~8%, filler surplus.
Composition includes following component and content when water dispersible granules are made：Active components A 0.5%~60%, activity at
Divide B0.5%~80%, dispersant 1%~12%, wetting agent 1%~8%, disintegrant 1%~10%, binder 0~8%, fill out
Expect surplus.
Composition includes following component and content when suspending agent is made：Active components A 0.5%~50%, active constituent
B0.5%~50%, dispersant 1%~10%, wetting agent 1%~10%, antifoaming agent 0.01%~2%, thickener 0~2%,
Antifreeze 0~8%, deionized water add to 100%.
Composition includes following component and content when aqueous emulsion is made：Active components A 0.5%~50%, active constituent
B0.5%~50%, emulsifier 1%~12%, antifreeze 0~8%, antifoaming agent 0.01%~2%, increases solvent 1%~20%
Thick dose 0~2%, deionized water add to 100%.
Composition includes following component and content when microemulsion is made：Active components A 0.5%~50%, active constituent
B0.5%~50%, solvent 1%~10%, antifreeze 0~8%, antifoaming agent 0.01%~2%, is gone emulsifier 3%~25%
Ionized water adds to 100%.
Composition includes following component and content when suspension emulsion is made：Active components A 0.5%~50%, active constituent
B0.5%~50%, emulsifier 1%~10%, dispersant 1%~10%, solvent 1%~20%, antifoaming agent 0.01%~2%,
Thickener 0~2%, antifreeze 0~8%, deionized water add to 100%.
Composition includes following component and content when microcapsule suspending agent is made：Active components A 0.5%~50%, activity at
Divide B0.5%~50%, macromolecule cyst material 1%~10%, dispersant 2%~10%, solvent 1%~10%, emulsifier
1%~7%, pH adjusting agent 0.01%~5%, antifoaming agent 0.01%~2%, deionized water add to 100%.
Composition includes following component and content when microcapsule suspension-suspendinagent agent is made：Active components A 0.5%~50% is lived
It is property ingredient B0.5%~50%, macromolecule cyst material 1%~12%, dispersant 1%~12%, wetting agent 1%~8%, molten
Agent 1%~15%, emulsifier 1%~8%, antifoaming agent 0.01%~2%, thickener 0~2%, pH adjusting agent 0.01%~
5%, deionized water adds to 100%.
The wettable powder the key technical indexes of the present invention：
The water dispersible granules the key technical indexes of the present invention：
The suspending agent the key technical indexes of the present invention：
The aqueous emulsion the key technical indexes of the present invention：
The microemulsion the key technical indexes of the present invention：
The suspension emulsion the key technical indexes of the present invention：
The microcapsule suspending agent the key technical indexes of the present invention：
The microcapsule suspension-suspendinagent agent the key technical indexes of the present invention：
The advantage of the invention is that：
(1) present composition has good synergy and lasting effect, preventive effect to be higher than single dose in a certain range；(2) agriculture
Medicinal dose is reduced, and is reduced residual quantity of the pesticide on crop, is mitigated environmental pollution；(3) fungicidal spectrum is expanded, to multiple diseases
Such as downy mildew, peronospora tabacina, epidemic disease, balck shank, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker have
Greater activity.
Specific implementation mode
With reference to embodiment to further instruction of the present invention, the percentage in embodiment is weight percentage, but
The present invention is not limited thereto.
Application Example one
1~13 wettable powder of embodiment
Fluorine ether bacterium amide, active constituent B, dispersant, wetting agent, filler are mixed, are uniformly mixed in mixed cylinder, through gas
Stream pulverizer remixes uniformly after crushing, you can wettable powder product of the present invention is made.Specifically it is shown in Table 1.
1 embodiment of table, 1~13 each component and content
14~26 water dispersible granules of embodiment
Fluorine ether bacterium amide, active constituent B, dispersant, wetting agent, disintegrant, filler etc. are obtained through air-flow crushing together
The grain size needed adds other auxiliary agents such as binder (can add can be not added with), obtains granulation materials.Item is quantified into feeding fluidisation
In bed granulating drier after granulation and drying, you can water dispersible granules product of the present invention is made, is specifically shown in Table 2.
2 embodiment of table, 14~26 each component and content
27~39 suspending agent of embodiment
By dispersant, wetting agent, antifoaming agent, thickener (can add can be not added with), antifreeze (can add can be not added with), by high speed
Shear-mixed is uniform, fluorine ether bacterium amide, active constituent B is added, ball milling 2~3 hours, make diameter of particle all exist in the ball mill
5 μm hereinafter, surplus is supplied with deionized water, you can suspending agent product of the present invention is made, is specifically shown in Table 3.
3 embodiment of table, 27~39 each component and content
40~46 aqueous emulsion of embodiment
Fluorine ether bacterium amide, active constituent B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；By deionization
Water, antifreeze (can add can be not added with), thickener (can add can be not added with), antifoaming agent mix, at uniform water phase.In high-speed stirring
It mixes down, oil phase is added in water phase, aqueous emulsion product of the present invention is made.Specifically it is shown in Table 4.
4 embodiment of table, 40~46 each component and content
47~53 microemulsion of embodiment
Fluorine ether bacterium amide, active constituent B are dissolved in the homogenizer equipped with solvent, by emulsifier, antifreeze, (can add can
Be not added with), antifoaming agent, be added in the homogenizer equipped with above-mentioned solution, surplus give after being supplied with deionized water strongly mix simultaneously
It homogenizes, finally obtains the transparent microemulsion product of the present invention of clear appearance.Specifically it is shown in Table 5.
5 embodiment of table, 47~53 each component and content
By cymoxanil, Propamocarb and salt in table 1~5, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or
Iprovalicarb exchanges, and novel formulation can be made.
54~56 suspension emulsion of embodiment
Dispersant, antifoaming agent, thickener (can add can be not added with), antifreeze (can add can be not added with) are mixed by high speed shear
Uniformly, fluorine ether bacterium amide is added, in the ball mill ball milling 2~3 hours, makes diameter of particle all at 5 μm hereinafter, fluorine ether bacterium is made
Then active constituent B, emulsifier, solvent and various auxiliary agents are directly emulsified with high speed agitator and arrive suspending agent by amide suspending agents
In, suspension emulsion product of the present invention is made.Specifically it is shown in Table 6.
6 embodiment of table, 54~56 each component and content
57~59 microcapsule suspending agent of embodiment
Fluorine ether bacterium amide, active constituent B, macromolecule cyst material, solvent are mixed, makes to be dissolved into homogeneous oil phase, cut
Under tangent condition, by oil phase be added to containing emulsifier, pH adjusting agent, dispersant, antifoaming agent aqueous phase solution in, surplus spend from
Sub- water is supplied, and two kinds of materials react in oil-water interfaces, forms high score ascus wall, it is well dispersed that the present composition is made
Microcapsule suspending agent product.Specifically it is shown in Table 7.
7 embodiment of table, 57~59 each component and content
60~62 microcapsule suspension-suspendinagent agent of embodiment
Active constituent B, macromolecule cyst material, solvent are mixed, make to be dissolved into homogeneous oil phase, by oil phase in shearing condition
Under be added to containing emulsifier, pH adjusting agent aqueous phase solution in, well dispersed microcapsule suspending agent is made.By dispersant, wet
Profit agent, antifoaming agent, thickener (can add can be not added with) are uniformly mixed by high speed shear, fluorine ether bacterium amide are added, in the ball mill
Ball milling 2~3 hours makes diameter of particle all at 5 μm hereinafter, suspending agent is made, suspending agent is then added to microcapsules and is suspended
In the aqueous phase solution of agent, deionized water supplies surplus, and the well dispersed microcapsule suspension-suspendinagent agent production of the present composition is made
Product.Specifically it is shown in Table 8.
8 embodiment of table, 60~62 each component and content
The embodiment of the present invention is the method being combined using Toxicity Determination and field trial.First pass through indoor virulence survey
It is fixed, the synergy ratio (SR) after two kinds of medicaments compound by a certain percentage is defined, SR ＜ 0.5 are antagonism, 0.5≤SR≤1.5
For summation action, SR ＞ 1.5 are synergistic effect, on this basis, then carry out field trial.
Test method：After prerun determines the effective inhibition concentration range of each medicament, medicament sets 5 respectively by active constituent content
A dosage processing, if clear water compares.Reference《Farm-chemical indoor determination test rule fungicide》It carries out, speed is grown using mycelia
Rate method measures virulence of the medicament to crop germ.Colony diameter is measured with crossing method after 72h, calculates the net growth of each processing
Amount, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter -5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) is converted into logarithm (x), with minimum
Square law acquires virulence regression equation (y=a+bx), and thus calculates the EC of each medicament50Value.Simultaneously according to Wadley methods
Two medicament different ratio synergy ratios (SR) are calculated, SR ＜ 0.5 are antagonism, and 0.5≤SR≤1.5 are summation action,
SR ＞ 1.5 are synergistic effect.Calculation formula is as follows：
Wherein：A, b is respectively active components A and active constituent B ratio shared in combination；
A is fluorine ether bacterium amide；
It is mould that B is selected from cymoxanil, Propamocarb and salt, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or figured silk fabrics
One of prestige is planted.
Application Example two：
For trying disease：Cucumber downy mildew, test medicine are provided by applicant, experimental design：It is determined by pilot study
Effective inhibition concentration range of both fluorine ether bacterium amide and cymoxanil different ratio mixture.
Toxicity test result
9 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to cucumber downy mildew with cymoxanil
As shown in Table 9, fluorine ether bacterium amide increases with the proportioning of cymoxanil compounding prevention cucumber downy mildew at 1: 80~60: 1
Effect ratio SR is all higher than 1.5, both illustrates that in 1: 80~60: 1 range, mixture shows synergistic effect, fluorine ether bacterium amide with
For the proportioning of cymoxanil 1: 20~10: 1, synergistic effect is more prominent, and synergy ratio is 2.30 or more, wherein 1: 9~4: 1 model
It is the most apparent in enclosing, it is tested through applicant and finds that the proportioning of fluorine ether bacterium amide and cymoxanil is 1: 20,1: 15,1: 10,1: 9,1:
8,1: 7,1: 6,1: 5,1: 4,1: 3,1: 2,1: 1,3: 2,2: 1,3: 1,4: 1,5: 1,6: 1,7: 1,8: 1,9: 1,10: 1, wherein fluorine
Synergy ratio is maximum when ether bacterium amide and cymoxanil weight ratio are 1: 3, and synergistic effect is the most apparent.
Application Example three：
For trying disease：Cucumber Blight, test medicine are provided by applicant, experimental design：Fluorine is determined by pilot study
Ether bacterium amide and Propamocarb active compound and effective inhibition concentration range of the two different ratio mixture.
Toxicity test result
10 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to Cucumber Blight with Propamocarb
As shown in Table 10, fluorine ether bacterium amide increases with the proportioning of Propamocarb compounding cucumber blight disease at 1: 80~60: 1
Effect ratio SR is all higher than 1.5, both illustrates that in 1: 80~60: 1 range, mixture shows synergistic effect, fluorine ether bacterium amide with
For the proportioning of Propamocarb 130~10: 1, synergistic effect is more prominent, and synergy ratio is 2.25 or more, wherein 1: 19~1: 1 model
It is the most apparent in enclosing, it is tested through applicant and finds that the proportioning of fluorine ether bacterium amide and Propamocarb is 1: 30,1: 25,1: 20,1: 19,1:
18、1∶17、1∶16、1∶15、1∶14、1∶13、1∶12、1∶11、1∶10、1∶9、1∶8、1∶7、1∶6、1∶5、1∶4、1∶3、1∶2、1∶
1,5: 1,10: 1, synergy ratio is maximum when wherein fluorine ether bacterium amide and Propamocarb weight ratio are 1: 10, and synergistic effect is the most apparent.
Application Example four：
For trying disease：Cucumber downy mildew, test medicine are provided by applicant, experimental design：It is determined by pilot study
Fluorine ether bacterium amide and technical-grade fosetyl-aluminum and effective inhibition concentration range of the two different ratio mixture.
Toxicity test result
11 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to cucumber downy mildew with phosethyl-Al
As shown in Table 11, fluorine ether bacterium amide prevents the proportioning of cucumber downy mildew 1: 80~60: 1 with phosethyl-Al compounding
When, synergy ratio SR is all higher than 1.5, illustrates that the two mixture in 1: 80~60: 1 range shows synergistic effect, fluorine ether bacterium
For the proportioning of amide and phosethyl-Al 1: 30~10: 1, synergistic effect is more prominent, synergy ratio 2.25 or more, wherein
It is the most apparent in 1: 19~1: 1 range, it is tested through applicant and finds that the proportioning of fluorine ether bacterium amide and phosethyl-Al is 1: 30,1:
25、1∶20、1∶19、1∶18、1∶17、1∶16、1∶15、1∶14、1∶13、1∶12、1∶11、1∶10、1∶9、1∶8、1∶7、1∶6、1∶
5,1: 4,1: 3,1: 2,1: 1,5: 1,10: 1, synergy ratio is most when wherein fluorine ether bacterium amide and phosethyl-Al weight ratio are 1: 14
Greatly, synergistic effect is the most apparent.
Application Example five：
For trying disease：Tomato blight, test medicine are provided by applicant, experimental design：Fluorine is determined by pilot study
Ether bacterium amide and pyrimorph active compound and effective inhibition concentration range of the two different ratio mixture.
Toxicity test result
12 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to tomato blight with pyrimorph
As shown in Table 12, fluorine ether bacterium amide compounds the proportioning for preventing tomato blight at 1: 80~60: 1 with pyrimorph,
Synergy ratio SR is all higher than 1.5, illustrates that the two mixture in 1: 80~60: 1 range shows synergistic effect, fluorine ether bacterium amide
For proportioning with pyrimorph 1: 20~10: 1, synergistic effect is more prominent, synergy ratio 2.25 or more, wherein 1: 14~
It is the most apparent in 4: 1 ranges, tested through applicant find the proportioning of fluorine ether bacterium amide and pyrimorph be 1: 20,1: 15,1: 10,
1: 9,1: 8,1: 7,1: 6,1: 5,1: 4,1: 3,1: 2,1: 1,3: 2,2: 1,3: 1,4: 1,5: 1,6: 1,7: 1,8: 1,9: 1,10: 1,
Synergy ratio is maximum when wherein fluorine ether bacterium amide and pyrimorph weight ratio are 1: 5, and synergistic effect is the most apparent.
Application Example six：
For trying disease：Target, test medicine are provided by applicant, experimental design：It is true by pilot study
Determine fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone active compound and effective inhibition concentration range of the two different ratio mixture.
Toxicity test result
13 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to target with fluorine thiazole pyrrole ethyl ketone
As shown in Table 13, the proportioning of fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone compounding prevention target 1: 80~
When 60: 1, synergy ratio SR is all higher than 1.5, illustrates that the two mixture in 1: 80~60: 1 range shows synergistic effect, fluorine
For the proportioning of ether bacterium amide and fluorine thiazole pyrrole ethyl ketone 1: 20~10: 1, synergistic effect is more prominent, synergy ratio 2.25 with
On, wherein it is the most apparent in 1: 9~4: 1 range, the proportioning for finding fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone is tested through applicant
For 1: 20,1: 15,1: 10,1: 9,1: 8,1: 7,1: 6,1: 5,1: 4,1: 3,1: 2,2: 3,1: 1,3: 2,2: 1,3: 1,4: 1,5: 1,
6: 1,7: 1,8: 1,9: 1,10: 1, synergy ratio is maximum when wherein fluorine ether bacterium amide and fluorine thiazole pyrrole ethyl ketone weight ratio are 2: 3, increases
Effect effect is the most apparent.
Application Example seven：
For trying disease：Cucumber samping off, test medicine are provided by applicant, experimental design：It is determined by pilot study
Fluorine ether bacterium amide and propamocarb active compound and effective inhibition concentration range of the two different ratio mixture.
Toxicity test result
14 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to cucumber samping off with propamocarb
As shown in Table 14, fluorine ether bacterium amide prevents the proportioning of cucumber samping off 1: 80~60 with propamocarb compounding
: when 1, synergy ratio SR is all higher than 1.5, illustrates that the two mixture in 1: 80~60: 1 range shows synergistic effect, fluorine ether
For the proportioning of bacterium amide and propamocarb 1: 30~10: 1, synergistic effect is more prominent, synergy ratio 2.30 or more,
It is the most apparent in wherein 1: 19~1: 1 range, it is tested through applicant and finds that the proportioning of fluorine ether bacterium amide and propamocarb is 1
∶30、1∶25、1∶20、1∶19、1∶18、1∶17、1∶16、1∶15、1∶14、1∶13、1∶12、1∶11、1∶10、1∶9、1∶8、1∶7、1
: 6,1: 5,1: 4,1: 3,1: 2,1: 1,5: 1,10: 1, increase when wherein fluorine ether bacterium amide and propamocarb weight ratio are 1: 10
It is maximum to imitate ratio, synergistic effect is the most apparent.
Application Example eight：
For trying disease：Wheat powdery mildew, test medicine are provided by applicant, experimental design：It is determined by pilot study
Fluorine ether bacterium amide and Acibenzolar active compound and effective inhibition concentration range of the two different ratio mixture.
Toxicity test result
15 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to wheat powdery mildew with Acibenzolar
As shown in Table 15, fluorine ether bacterium amide compounds the proportioning for preventing wheat powdery mildew at 1: 80~60: 1 with Acibenzolar,
Synergy ratio SR is all higher than 1.5, illustrates that the two mixture in 1: 80~60: 1 range shows synergistic effect, fluorine ether bacterium amide
For proportioning with Acibenzolar 1: 10~20: 1, synergistic effect is more prominent, and synergy ratio is 2.25 or more, wherein 1: 4~9: 1
It is the most apparent in range, it is tested through applicant and finds that the proportioning of fluorine ether bacterium amide and Acibenzolar is 1: 10,1: 5,1: 4,1: 3,1:
2,1: 1,2: 1,3: 1,4: 1,5: 1,6: 1,7: 1,8: 1,9: 1,10: 1,15: 1,20: 1, wherein fluorine ether bacterium amide and Acibenzolar weight
Synergy ratio is maximum when amount is than being 2: 1, and synergistic effect is the most apparent.
Application Example nine：
For trying disease：Downy mildew of garpe, test medicine are provided by applicant, experimental design：It is determined by pilot study
Fluorine ether bacterium amide and iprovalicarb active compound and effective inhibition concentration range of the two different ratio mixture.
Toxicity test result
16 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to downy mildew of garpe with iprovalicarb
As shown in Table 16, fluorine ether bacterium amide compounds the proportioning for preventing downy mildew of garpe at 1: 80~60: 1 with iprovalicarb,
Synergy ratio SR is all higher than 1.5, illustrates that the two mixture in 1: 80~60: 1 range shows synergistic effect, fluorine ether bacterium amide
For proportioning with iprovalicarb 1: 20~10: 1, synergistic effect is more prominent, and synergy ratio is 2.30 or more, wherein 1: 9~4: 1
It is the most apparent in range, it is tested through applicant and finds that the proportioning of fluorine ether bacterium amide and iprovalicarb is 1: 20,1: 15,1: 10,1: 9,1
: 8,1: 7,1: 6,1: 5,1: 4,1: 3,1: 2,2: 3,1: 1,3: 2,2: 1,3: 1,4: 1,5: 1,6: 1,7: 1,8: 1,9: 1,10: 1,
Synergy ratio is maximum when wherein fluorine ether bacterium amide and iprovalicarb weight ratio are 2: 3, and synergistic effect is the most apparent.
It is found through experiment that：Fluorine ether bacterium amide with after active constituent B compounding in various crop downy mildew, peronospora tabacina,
The prevention of epidemic disease, balck shank, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker has apparent synergy to make
With synergy ratio is 1.5 or more.
Effect experiment part：Test medicine is researched and developed by applicant, is provided, 10% fluorine ether bacterium amide suspending agents of comparison medicament
(autogamy), 10% cymoxanil suspending agent (autogamy), 30% Propamocarb aqua (purchased in market), 40% phosethyl-Al wettable powder
(purchased in market), 15% pyrimorph suspending agent (autogamy), 10% fluorine thiazole pyrrole ethyl ketone suspending agent (autogamy), 30% propamocarb
Aqua (purchased in market), 10% Acibenzolar suspending agent (autogamy), 15% iprovalicarb wettable powder (autogamy).
Ten fluorine ether bacterium amide of Application Example and active constituent B and its compounding prevention cucumber downy mildew test of pesticide effectiveness
This experiment is arranged in Xi'an City, Shanxi Province, and the cucumber downy mildew state of an illness is investigated before medicine, in state of an illness first time at initial stage dispenser,
Every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows：
17 fluorine ether bacterium amide of table and active constituent B and its compounding prevention cucumber downy mildew test of pesticide effectiveness
As can be seen from Table 17, cucumber downy mildew can be effectively prevented after fluorine ether bacterium amide and active constituent B and its compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.It is right simultaneously
Powdery mildew of cucumber, gray mold also have good preventive effect, drug effect to be up to 96% or more.
Ten monofluoro-ether bacterium amide of Application Example and active constituent B and its compounding prevention rice blast test of pesticide effectiveness
This test arrangement investigates the rice blast state of an illness before Shaanxi Province's Hanzhong City, medicine, in state of an illness first time at initial stage dispenser,
Every dispenser in 7 days is primary, altogether dispenser 2 times.3 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 7 days, 15 days.It is real
It is as follows to test result：
18 fluorine ether bacterium amide of table and active constituent B and its compounding prevention rice blast test of pesticide effectiveness
As can be seen from Table 18, rice blast can be effectively prevented after fluorine ether bacterium amide and active constituent B and its compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long, had no adverse effects to target crop in experiment scope of medication.It is right simultaneously
Rice sheath blight disease, samping off also have good preventive effect, drug effect to be up to 96% or more.
Ten difluoro ether bacterium amide of Application Example and active constituent B and its compounding prevention apple mildew test of pesticide effectiveness
This test arrangement investigates the apple mildew state of an illness before Shaanxi Province's Weinan City, medicine, in state of an illness first time at initial stage dispenser,
Every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows：
19 fluorine ether bacterium amide of table and active constituent B and its compounding prevention apple mildew test of pesticide effectiveness
As can be seen from Table 19, fluorine ether bacterium amide prevents apple mildew, prevention with efficiency after active constituent B and its compounding
Effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.
Ten trifluoro bacterium amide of Application Example and active constituent B and its compounding prevention tomato late blight test of pesticide effectiveness
This test arrangement investigates the tomato late blight state of an illness before Xi'an City, Shanxi Province, medicine, in state of an illness first time at initial stage dispenser,
Every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows：
20 fluorine ether bacterium amide of table and active constituent B and its compounding prevention tomato late blight disease test of pesticide effectiveness
As can be seen from Table 20, tomato late blight can be effectively prevented after fluorine ether bacterium amide and active constituent B and its compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.It is right simultaneously
Graw mold of tomato also has good preventive effect, drug effect to be up to 96% or more.
Ten tetrafluoro ether bacterium amide of Application Example and active constituent B and its compounding prevention downy mildew of garpe test of pesticide effectiveness
This test arrangement investigates the downy mildew of garpe state of an illness before Shaanxi Province's Weinan City, medicine, in state of an illness first time at initial stage dispenser,
Every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after second of dispenser, disease index is investigated respectively and calculates preventive effect within 14 days, 30 days.
Experimental result is as follows：
21 fluorine ether bacterium amide of table and active constituent B and its compounding prevention downy mildew of garpe test of pesticide effectiveness
As can be seen from Table 21, downy mildew of garpe can be effectively prevented after fluorine ether bacterium amide and active constituent B and its compounding, prevented
The preventive effect that effect is superior to single dose is controlled, and preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.It is right simultaneously
Uncinula necator, gray mold also have good preventive effect, drug effect to be up to 96% or more.
15 fluorine ether bacterium amide of Application Example and active constituent B and its compounding prevention target test of pesticide effectiveness
This test arrangement investigates the target state of an illness before Shaanxi Province's Weinan City, medicine, is applied for the first time in state of an illness initial stage
Medicine, every dispenser in 7 days is primary, altogether dispenser 2 times.7 days after second of dispenser, disease index is investigated respectively and is calculated anti-within 14 days, 30 days
Effect.Experimental result is as follows：
22 fluorine ether bacterium amide of table and active constituent B and its compounding prevention target test of pesticide effectiveness
As can be seen from Table 22, target can be effectively prevented after fluorine ether bacterium amide and active constituent B and its compounding,
Control effect is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.
The experiment by different places throughout the country obtains afterwards, fluorine ether bacterium amide and cymoxanil, Propamocarb, Propamocarb salt
To the downy mildew in various crop after hydrochlorate, phosethyl-Al, fluorine thiazole pyrrole ethyl ketone, pyrimorph, Acibenzolar or iprovalicarb compounding
The Common Diseases such as disease, peronospora tabacina, epidemic disease, balck shank, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew, canker
Preventive effect 95% or more, is better than single dose preventive effect, and synergistic effect is apparent.
Claims (6)
1. a kind of compound pesticide composition of fluorine-containing ether bacterium amide, effective active composition is active components A and active constituent B,
It is characterized in that：Active components A and the weight ratio of active constituent B are 1: 80~60: 1, and the active components A is selected from fluorine ether bacterium acyl
Amine, active constituent B are pyrimorph.
2. the compound pesticide composition of fluorine-containing ether bacterium amide according to claim 1, it is characterised in that：Active components A with
The weight ratio of active constituent B is 1: 60~40: 1.
3. the compound pesticide composition of fluorine-containing ether bacterium amide according to claim 2, it is characterised in that：
The weight ratio of fluorine ether bacterium amide and pyrimorph is 1: 20~10: 1.
4. the compound pesticide composition of fluorine-containing ether bacterium amide described in any one of claim 1 to 3, it is characterised in that：
Wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent or micro-capsule is made in composition
Suspension-suspending agent.
5. the compound pesticide composition of fluorine-containing ether bacterium amide according to claim 4 is used to prevent the purposes of crop disease.
6. purposes according to claim 5, it is characterised in that：The disease is downy mildew, peronospora tabacina, epidemic disease, black
Shin disease, samping off, banded sclerotial blight, rice blast, gray mold, powdery mildew or canker.
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| CN102754650A (en) * | 2012-07-24 | 2012-10-31 | 山东省联合农药工业有限公司 | Desflurane bacteria amide compound bactericide |
| CN102792952A (en) * | 2012-09-12 | 2012-11-28 | 山东棉花研究中心 | Bactericide composition for preventing and controlling cotton disease |
| CN102845436A (en) * | 2012-09-19 | 2013-01-02 | 山东省联合农药工业有限公司 | Bactericide composition containing fluoro-ether bacterium amide and dimethomorph |
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| CN103444733B (en) * | 2013-05-31 | 2015-04-15 | 山东省联合农药工业有限公司 | Sterilization composition containing fluoroether bacteria amide and iprovalicarb |
| CN104412988A (en) * | 2013-08-28 | 2015-03-18 | 张通 | Antibacterial composition containing fluoride ether bacteria amide and triazoles |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102754650A (en) * | 2012-07-24 | 2012-10-31 | 山东省联合农药工业有限公司 | Desflurane bacteria amide compound bactericide |
| CN102792952A (en) * | 2012-09-12 | 2012-11-28 | 山东棉花研究中心 | Bactericide composition for preventing and controlling cotton disease |
| CN102845436A (en) * | 2012-09-19 | 2013-01-02 | 山东省联合农药工业有限公司 | Bactericide composition containing fluoro-ether bacterium amide and dimethomorph |
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| Title |
|---|
| 新型杀菌剂氟醚菌酰胺对黄瓜霜霉病的毒力和田间药效评价;张 睿 等;《农药》;20130831;第58卷(第8期);第596-598页 * |
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Effective date of registration: 20191129 Address after: 715500 Pucheng County High-tech Industrial Development Zone, Weinan City, Shaanxi Province Patentee after: SHAANXI MEIBANG PHARMACEUTICAL GROUP Co.,Ltd. Address before: 715500 middle section of North Ring Road, Pucheng County, Shaanxi Patentee before: Zhang Tong |
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