CN104256653A

CN104256653A - Leukemia total-nutrient formula food

Info

Publication number: CN104256653A
Application number: CN201410529118.3A
Authority: CN
Inventors: 胡安然
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-10-10
Filing date: 2014-10-10
Publication date: 2015-01-07

Abstract

The invention provides a total-nutrient formula food or specific total-nutrient formula food or non-total-nutrient formula food for being eaten by a leukemia patient. The total-nutrient formula food is formed by crushing and mixing multiple medicine and food dual-purpose traditional Chinese medicine extract essences extracted by using a pre-hydrolyzed SBE technology and multiple microencapsulated probiotics as well as oligopeptide, prebiotics, amino acid, carbohydrate, multivitamin and mineral extracted by biological enzymolysis in combination with the physical characteristics of the leukemia patient according to the requirements of the General Rules for Special Medical Use Formula Food. The leukemia total-nutrient formula food has the benefit that the leukemia total-nutrient formula food only can be taken as a single source of nutrients to meet the nutritional demands of the leukemia patient, but also can have the efficacies of removing stasis, tonifying qi and enriching the blood, clearing away heat and detoxifying, promoting blood circulation to remove blood stasis, promoting the circulation of qi and removing stasis, cooling blood and stopping bleeding, and nourishing yin.

Description

The full nutritional formulas of leukemia

Technical field

The invention belongs to integration of drinking and medicinal herbs class formula and food technology field, specifically the Traditional Chinese Medicine marrow of " Chinese medicine of integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds the full nutritional formulas of leukemia, specific full nutritional formulas or the non-fully nutritional formulas made for auxiliary material with small peptide, prebiotics, amino acid, carbohydrate, B B-complex, composite mineral matter.

Background technology

Leukaemia is the malignant disease that a kind of reason of hemopoietic system is not yet completely clear and definite, its pathological characteristic is a large amount of leukaemia's extensively and uncontrolledly hyperplasia in body, there are dry marrow and other Organ and tissues many, and enter in peripheral blood, main clinical manifestation has heating in various degree, anaemia, hemorrhage, liver spleen and enlargement of lymph nodes, according to the immature degree of leukaemia and leukemic natural history, mainly be divided into acute leukemia and the large class of chronic leukemia two, the former is mainly ALL (anxious pouring) and acute non lymphocytic leukemia (anxious non-pouring) two classes, acute leukemia is multiple is born in children and youth, chronic leukemia with adult and the elderly common, leukemic prognosis is poor, especially acute leukemia, leukaemia belongs to the traditional Chinese medical science " blood trouble ", " consumptive disease ", the category such as " to gather ", the leukemic cause of disease is the positive unsaturated vapor of body, empty in vital essence, touch the gas emitting pest poison, the evil invasion and attack of poison, injure battalion cloudy, involve in kidney, bone marrow damage and causing a disease, pathological change is by the positive unsaturated vapor of dry body, be subject to the evil invasion and attack of poison, from superficies to interior, weakened body resistance heresy is contained, injure battalion cloudy, involve in kidney, bone marrow damage, green blood is not enough, there is the deficiency of blood, cloudy essence is impaired, interior hot smoking is steamed, heat damaging blood and vessels, compel the absurd row of blood, or prolonged illness wasting QI-blood vapour does not take the photograph blood, causes blood trouble, because weakened body resistance being invaded by exogenous pathogen,invasion of exogenous pathogen or cloudy blood trouble lose, ying blood heat is vehement, and visible high heat is persistent, and with the passing of time, qi and blood more loses the course of disease, qi depression to blood stasis, and train of thought is blocked, and accumulates in the costal region, and forms scar block.If not to the greatest extent, then often repeatedly, heresy declines weakened body resistance malicious heresy, and causes QIYINLIANGXU; " integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science; The traditional Chinese medical science is always emphasized " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet; Allow people dispel slight illness in the process enjoying cuisines, avoid and have an injection, take medicine, even pain of surgery.

For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And the full nutritional formulas of wholefood clear stipulaties: 2.1.1 in China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 specific full nutritional formulas: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition.

Traditional Chinese medical science traditional medicine is thought: " spleen (i.e. digestive system) is the foundation of acquired constitution ", and stomach health is healthy basis, and 99% of human nutrition needs by intestinal absorption, and intestinal bowel disease is also the source of ten thousand diseases; But along with the age is larger, in enteron aisle, profitable strain (probio) ratio reduces gradually; As Bifidobacterium Bifidum accounts for 98% infant period, be down to 10% to during the middle age, within 65 years old, only account for 5% later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies display, normal flora human consumption, immunity and disease-resistant etc. in have many irreplaceable effects; The change of gut flora composition and the generation of various diseases, particularly intestines problem develop closely related, and find from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one intervenes control method safely and effectively.

Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter composition compound prescription, utilize the product that probio is primary raw material in addition, but also do not find the constitutive character in conjunction with patients with blood cancer, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials is the full nutritional formulas that auxiliary material is made, specific full nutritional formulas or similar products.

goal of the invention

The object of the invention is on the theoretical treatment method of succession traditional Chinese medical science marrow, the initiative extract by the probio of multiple raising body immunity and " Chinese medicine of integration of drinking and medicinal herbs " compound combines, add with small peptide, amino acid, carbohydrate, multivitamin, several mineral materials is auxiliary material, patients with blood cancer institute essential nutrients can not only be supplemented, improve body nutrition condition, can also and utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutritional formulas that the acceptable applicable patients with blood cancer of people eat, specific full nutritional formulas or non-fully nutritional formulas.

summary of the invention:

This R&D team is according to the requirement of " special medicine purposes formula food general rule ", in conjunction with the constitutive character of patients with blood cancer, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears benefit ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets patients with blood cancer, also has the broken long-pending stasis of blood of dispelling, blood-enrich, clearing heat and detoxicating, promoting blood circulation and removing blood stasis, promoting QI to circulate and dispersing the agglomeration of the pathogens, cooling blood and hemostasis, the full nutritional formulas of enriching yin effect, specific full nutritional formulas or non-fully nutritional formulas (compound prescription be combined into).

1, the main component of the present invention's formula is:

Chinese medical extract is dirty with being adjusted to main principle from the liver,spleen,kidney three theory of traditional Chinese medical science according to the constitutive character of patients with blood cancer, utilizes the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and chooses following several large class medicine and carry out compatibility; Wherein: Radix Astragali invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic; Radix Codonopsis has tonifying middle-Jiao and Qi, invigorating the spleen benefit lung, anticancer, step-down, anti anoxia, anti-ageing effect, body immunity can also be strengthened, improve the activity of superoxide dismutase, strengthen the ability eliminating free radical, there is the effect of Gastrointestinal motility adjustment, antiulcer, gastric acid secretion inhibiting, reduction pepsin activity; Chinese angelica blood supplementing; Invigorate blood circulation; The dried rhizome of rehmannia has effect of clearing heat and cooling blood, beneficial Yin and promoting production of body liquid; Cultivated land is enriched blood yin-nourishing, life essence-filling, marrow-benefitting; Strengthening spleen and lung mended by radix pseudostellariae; Nourishing generate fluid; The tuber of dwarf lilyturf nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire; Reticulate millettia is enriched blood promoting circulation of blood, clearing and activating the channels and collaterals; Fleece-flower root temperature bitter and puckery flavor, bitter kidney tonifying, temperature compensation liver, can restrain vital essence, so beneficial liver of nourishing blood, controlling nocturnal emission with astringent drugs kidney-nourishing, muscle reinforcing and bone strengthening, Wu Fa is tonic medicine; Bighead atractylodes rhizome strengthening the spleen and replenishing qi, eliminating dampness Li Shui, hidroschesis, antiabortive; Radix Isatidis heat-clearing, removing toxic substances, cool blood, relieve sore throat; Great burdock achene has dispelling wind and heat from the body, a surname's lung promoting eruption, relieve sore throat dissipating bind, effect of removing toxicity for detumescence; Safflower, activating blood to promote menstruation, blood stasis removing analgesic; Root bark of tree peony clearing heat and cooling blood, promoting blood circulation to remove blood stasis; Edible tulip has clearing heat and detoxicating, the effect of the carbuncle that disappears dissipating bind; Radix et Rhizoma Gynurae divaricatae is hypoglycemic, clearing heat and cooling blood; Promoting blood circulation and stopping pain; Hemostasis;

Medicinal and edible Chinese medicine extract of the present invention refers to the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, the dried rhizome of rehmannia, cultivated land, radix pseudostellariae, the tuber of dwarf lilyturf, reticulate millettia, the fleece-flower root, the bighead atractylodes rhizome, Radix Isatidis, the Radix Astragali, great burdock achene, Cordyceps sinensis, lucidum spore powder, the stem of noble dendrobium, safflower, the shell of seaear, the root bark of tree peony, edible tulip, Cordyceps militaris, Radix et Rhizoma Gynurae divaricatae, ginseng, dandelion, cordate houttuynia, peach kernel, cape jasmine, donkey-hide gelatin, Exocarpium Citri Rubrum, matrimony vine, sealwort, sophora flower, dried orange peel, radix polygonati officinalis, Poria cocos, Radix Glycyrrhizae, lophatherum gracile, jujube, longan, Bee Pollen, peanut, dark plum, italian-jobi jen, fructus amomi, Radix Glycyrrhizae, balloonflower root wherein more than 4 kinds or all, biological enzymolysis or prehydrolysis SBE is adopted to extract and microencapsulation, mixture after spray-dried and cryodesiccated extract.

2, multiple probio: make probio major part can arrive enteron aisle by the strong acid environment of stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote the absorption to trace element, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, obviously can reduce the level of intestinal endotoxemia and the generation of preventing liver injury; Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by urease-producing in suppression enteron aisle and the growth of producing ammonium bacteria, builds up resistance;

Multiple probio of the present invention all adopts the probio after microencapsulation, except streptococcus thermophilus, wherein Bifidobacterium: refer to that bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum are wherein a kind of, several or all mix; Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus are wherein a kind of, several or all mix.

3, small peptide: be oligopeptide, refer to the small molecule protein utilizing bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is at below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need directly to absorb through digestion, bioavailability is high, absorbing and utilizing the amino acid and complete protein that are better than dissociating, can be applicable in Protein intake food, especially for the crowd that abilities of digestive and absorption is low, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function improving small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,

Small peptide of the present invention refers to that marine collagen peptide, wheat oligopeptide, maize oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.

4. prebiotics: with short probio intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most enteron aisle spoilage organisms, but beneficial bacteria in human body can be promoted---the growth and breeding of lactobacillus, Bifidobacterium, thus spoilage organisms can be suppressed to grow, contribute to improving and maintaining enteron aisle normal function; Long-term edible can to delay senility, defaecation, raising immunity, the absorptivity that alleviates burden of liver, improve nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, knot intestinal pH is reduced, suppresses the growth of intestinal harmful bacillus; Water-Electrolyte in small intestine is made to be trapped in enteric cavity, produce and highly ooze effect, stimulate enterocinesia to cause laxative, thus promote the discharge of intestinal endotoxin and other toxicants, lactulose also can directly endotoxin in deactivation enteron aisle, reduce gut pH, extensively model is applied to the treatment of enhancing patient resistance;

Prebiotics of the present invention is 2 classes

A. very strong field planting effect prebiotics is had to external source probio: the extract of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, stachyose, yeast wherein several or all mix;

B. common prebiotics: oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix;

Originally oligoisomaltose, stachyose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix is referred to.

5, carbohydrate: carbohydrate is by carbon, hydrogen and oxygen three kinds of element compositions, it is for human body provides nutrient the most cheap in three of heat energy kinds of main nutrients, when taking in sufficient, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,

Carbohydrate of the present invention refers to glucose, fructose, galactolipin, lactose, Arabinose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

6. amino acid: be divided into essential amino acid and nonessential amino acid, is the base unit forming protein, gives protein specific molecular morphosis, make it have biochemical activity; Absorb appropriate methionine and contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances; Leucine can repair muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress cancer growth, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to changing the ammonia in blood into urea and excreting out; For hyperammonemia, hepatic dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses nervous by vegetative nerve and alimentary canal that is that cause festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improving water flood and adjustment mood;

Amino acid of the present invention refers to Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

7. vitamin and mineral matter:

Vitamin and mineral matter are the nutrients of needed by human, the nutrient of the vitamin added in the present invention to be vitamin and mineral matter be needed by human;

The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix;

The mineral matter added in the present invention is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;

In the present invention, the addition of vitamin and minerals is with reference to GB14880 " food enrichment use sanitary standard ", GB2760 " food additives use standard " performs, now for 1000g finished product, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

8. the present invention is with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat leukemia significantly improves compared with the like product of market.

9. adopt above-mentioned integrated innovation technique various batching to be mixed solid beverage, the granule of making powdery, and be distributed into 10g/ bag, with about 150ml, 45 degree of warm waters are directly drunk or are taken in through nasal feeding after dissolving; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

The characteristic of this full nutritional formulas of filling a prescription and the following aspects is mainly manifested in the effect of body:

1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with the constitutive character of patients with blood cancer, the achievement in research developments such as the advanced physiology of comprehensive nowadays American Harvard University, medicine, nutrition and clinical practice, vary with each individual, gold compatibility.

2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is adopted to be primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter for auxiliary material, the organic assembling of various batching, various function is merged, and by the synergy between active ingredient, humidification effect.

3. have effective absorbency, utilize formula of the present invention, various component adopts the food of suitable ratio collocation preparation, in isotonic state after a certain amount of water-soluble solution, small intestine can be arrived quickly through stomach, absorb fast, completely, patients with blood cancer's desired nutritional can be supplemented rapidly.

4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicine, containing several functions active component, not only increase the concentration of function factor, reduce the absorption of various impurity, contribute to alleviating liver kidney burden, have and strengthen the effect of resistance of human body, also have the broken long-pending stasis of blood of dispelling, blood-enrich, clearing heat and detoxicating, promoting blood circulation and removing blood stasis, promoting QI to circulate and dispersing the agglomeration of the pathogens, cooling blood and hemostasis, enriching yin effect.

5. probio contained in the present invention's formula, multiple probio can safeguard enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and raising body are to the absorption of calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve host to the tolerance of radioactive ray, lactobacillus significantly increases intestinal mucosal immune globulin A (SIgA) content, to body intestinal mucosa local immunity, there is regulating action, regulate stomach, intestines Tiny ecosystem, calcium can be improved, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, the absorption of cholesterol can also be reduced.

6. formula food of the present invention with the food source property bioactive short peptide in multiple source for nitrogenous source, because small peptide does not need digestion and Absorbable rod, more be conducive to the utilization of body, can effectively improve patients with blood cancer's negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, improves the absorbability of intestinal mucosa.

7. this prescription have employed this team by over nearly 3 year to the achievement that the key technology of probio field planting mechanism in enteron aisle is studied, improve " Chinese medicine of integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence combining prebiotics can play the key elements such as field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula greatly strengthen the field planting effect to external source probio.

8. prebiotics contained in the present invention's formula; by promoting the growth and breeding of probio in intestines; suppress the growth of spoilage organisms; form one protective barrier at intestinal mucosal surface simultaneously; the damage of enteron aisle spoilage organisms to intestinal mucosa can be resisted; reduce the absorption of intestinal toxic material; intestines peristalsis can also be promoted; accelerate the discharge of residuals in intestines; leukemia can be prevented; and by promoting that the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy.

9, in the present invention's formula, contained carbohydrate is for human body provides three of heat energy kinds of main nutrients, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce.

10, contained in the present invention's formula amino acid, it is the base unit forming protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances, muscle can be repaired, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development.

11, formula food of the present invention is containing multivitamin and mineral matter, can supplement rapidly the micronutrient needed for patients with blood cancer, small peptide by with the chelating of calcium, iron, zinc etc. after, further increase the absorptivity of mineral matter element.

12, not fatty and cholesterol in the present invention's formula, while supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, avoid the adverse effect of the high protein diet such as meat, egg.

Detailed description of the invention

Below by following examples, the invention will be further described, and it will contribute to understanding the present invention.

Embodiment one

Realizing the full nutritional formulas of the object of the invention leukemia is constitutive character in conjunction with patients with blood cancer, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide for primary raw material, the food made for auxiliary material with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;

Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose: Radix Astragali 10g, Radix Codonopsis 10g, Radix Angelicae Sinensis 10g, dried rhizome of rehmannia 10g, cultivated land 10g, radix pseudostellariae 10g, the tuber of dwarf lilyturf 10g, reticulate millettia 8g, fleece-flower root 8g, bighead atractylodes rhizome 8g, Radix Isatidis 8g, Radix Astragali 8g, great burdock achene 8g, Cordyceps sinensis 8g, lucidum spore powder 8g, stem of noble dendrobium 8g, safflower 8g, shell of seaear 8g, root bark of tree peony 8g, edible tulip 6g, Cordyceps militaris 6g, Radix et Rhizoma Gynurae divaricatae 6g, ginseng 6g, dandelion 6g, cordate houttuynia 6g, peach kernel 6g, cape jasmine 6g, donkey-hide gelatin 6g, Exocarpium Citri Rubrum 6g, matrimony vine 6g, sealwort 6g, sophora flower 6g, dried orange peel 6g, radix polygonati officinalis 6g, Poria cocos 4g, lophatherum gracile 4g, jujube 4g, longan 4g, Bee Pollen 4g, peanut 4g, dark plum 4g, italian-jobi jen 4g, fructus amomi 4g, Radix Glycyrrhizae 4g, balloonflower root 4g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 100g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

First will to be the Radix Astragali during making, Radix Codonopsis, Radix Angelicae Sinensis, the dried rhizome of rehmannia, cultivated land, radix pseudostellariae, the tuber of dwarf lilyturf, reticulate millettia, the fleece-flower root, the bighead atractylodes rhizome, Radix Isatidis, the Radix Astragali, great burdock achene, safflower, the shell of seaear, the root bark of tree peony, edible tulip, Cordyceps militaris, Radix et Rhizoma Gynurae divaricatae, ginseng, dandelion, cordate houttuynia, peach kernel, cape jasmine, Exocarpium Citri Rubrum, matrimony vine, sealwort, sophora flower, dried orange peel, radix polygonati officinalis, Poria cocos, Radix Glycyrrhizae, lophatherum gracile, jujube, longan, peanut, dark plum, fructus amomi, balloonflower root, the membrane of a chicken's gizzard, Chinese yam, coix seed, Gorgon fruit soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, lucidum spore powder, Cordyceps sinensis, the stem of noble dendrobium, Bee Pollen, donkey-hide gelatin, prebiotics, amino acid, carbohydrate, carry out pasteurization after multivitamin and mineral matter are pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, with about 150ml, 45 degree of warm waters are directly drunk or are taken in through nasal feeding after dissolving, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

Embodiment two

The full nutritional formulas of above-mentioned leukemia also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 12g, Radix et Rhizoma Gynurae divaricatae 12g, ginseng 12g, dandelion 12g, cordate houttuynia 10g, peach kernel 10g, cape jasmine 10g, donkey-hide gelatin 10g, Exocarpium Citri Rubrum 10g, matrimony vine 8g, sealwort 8g, sophora flower 8g, dried orange peel 8g, radix polygonati officinalis 8g, Poria cocos 8g, Radix Glycyrrhizae 8g, lophatherum gracile 6g, jujube 6g, longan 6g, Bee Pollen 6g, peanut 6g, dark plum 4g, italian-jobi jen 4g, fructus amomi 4g, balloonflower root 4g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

Embodiment three

The full nutritional formulas of above-mentioned leukemia also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 12g, Radix et Rhizoma Gynurae divaricatae 12g, ginseng 12g, dandelion 12g, cordate houttuynia 10g, peach kernel 10g, cape jasmine 10g, donkey-hide gelatin 10g, Exocarpium Citri Rubrum 10g, matrimony vine 8g, sealwort 8g, sophora flower 8g, dried orange peel 8g, radix polygonati officinalis 8g, Poria cocos 8g, Radix Glycyrrhizae 8g, lophatherum gracile 6g, jujube 6g, longan 6g, Bee Pollen 6g, peanut 6g, dark plum 4g, italian-jobi jen 4g, fructus amomi 4g, balloonflower root 4g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 150g, carbohydrate 100g.

The present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat leukemia significantly improves compared with the like product of market.

Claims

1. the full nutritional formulas of leukemia, it is characterized in that the constitutive character in conjunction with patients with blood cancer, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide for primary raw material, the food made for auxiliary material with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;

Its preparation method is first by the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, the dried rhizome of rehmannia, cultivated land, radix pseudostellariae, the tuber of dwarf lilyturf, reticulate millettia, the fleece-flower root, the bighead atractylodes rhizome, Radix Isatidis, the Radix Astragali, great burdock achene, safflower, the shell of seaear, the root bark of tree peony, edible tulip, Cordyceps militaris, Radix et Rhizoma Gynurae divaricatae, ginseng, dandelion, cordate houttuynia, peach kernel, cape jasmine, Exocarpium Citri Rubrum, matrimony vine, sealwort, sophora flower, dried orange peel, radix polygonati officinalis, Poria cocos, Radix Glycyrrhizae, lophatherum gracile, jujube, longan, peanut, dark plum, fructus amomi, balloonflower root, the membrane of a chicken's gizzard, Chinese yam, coix seed, Gorgon fruit soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, lucidum spore powder, Cordyceps sinensis, the stem of noble dendrobium, Bee Pollen, donkey-hide gelatin, prebiotics, amino acid, carbohydrate, carry out pasteurization after multivitamin and mineral matter are pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, with about 150ml, 45 degree of warm waters are directly drunk or are taken in through nasal feeding after dissolving, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

2. the full nutritional formulas formula of leukemia according to claim 1, it is characterized in that described medicine-food two-purpose Chinese herbal medicine extract is: the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, the dried rhizome of rehmannia, cultivated land, radix pseudostellariae, the tuber of dwarf lilyturf, reticulate millettia, the fleece-flower root, the bighead atractylodes rhizome, Radix Isatidis, the Radix Astragali, great burdock achene, Cordyceps sinensis, lucidum spore powder, the stem of noble dendrobium, safflower, the shell of seaear, the root bark of tree peony, edible tulip, Cordyceps militaris, Radix et Rhizoma Gynurae divaricatae, ginseng, dandelion, cordate houttuynia, peach kernel, cape jasmine, donkey-hide gelatin, Exocarpium Citri Rubrum, matrimony vine, sealwort, sophora flower, dried orange peel, radix polygonati officinalis, Poria cocos, Radix Glycyrrhizae, lophatherum gracile, jujube, longan, Bee Pollen, peanut, dark plum, italian-jobi jen, fructus amomi, Radix Glycyrrhizae, balloonflower root wherein more than 4 kinds or all mix.

3. the full nutritional formulas formula of leukemia according to claim 1, is characterised in that and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food according to described formula mixing.

4. the full nutritional formulas formula of leukemia according to claim 1, is characterized in that described prebiotics is. have that very strong field planting effect prebiotics is Chinese yam to external source probio, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, the extract of jerusalem artichoke, stachyose, yeast and common prebiotics wherein several or all mix.

5. according to rightrequire the full nutritional formulas formula of leukemia described in 1, it is characterized in that described amino acid is Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

6. the full nutritional formulas formula of leukemia according to claim 1, is characterized in that described carbohydrate is Arabinose, glucose, fructose, galactolipin, lactose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

7. the full nutritional formulas formula of leukemia according to claim 1, is characterized in that with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, make product prevent and treat leukemia effect and significantly improve compared with the like product of market.

8. the full nutritional formulas formula of leukemia according to claim 1, is characterized in that described vitamin is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix; Described mineral matter is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix.

9. the full nutritional formulas formula of leukemia according to claim 1, is characterized in that described small peptide is marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide is wherein a kind of, several or all mix.