Nothing Special   »   [go: up one dir, main page]

CN104203290A - 消毒涂药器和包装技术 - Google Patents

消毒涂药器和包装技术 Download PDF

Info

Publication number
CN104203290A
CN104203290A CN201380007893.6A CN201380007893A CN104203290A CN 104203290 A CN104203290 A CN 104203290A CN 201380007893 A CN201380007893 A CN 201380007893A CN 104203290 A CN104203290 A CN 104203290A
Authority
CN
China
Prior art keywords
medical
applicator
antibacterial
disinfectant
permeable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380007893.6A
Other languages
English (en)
Inventor
帕特里克·O·滕尼肯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hyprotek Inc
Original Assignee
Hyprotek Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyprotek Inc filed Critical Hyprotek Inc
Publication of CN104203290A publication Critical patent/CN104203290A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B50/33—Trays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/20—Holders specially adapted for surgical or diagnostic appliances or instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0246—Adhesive bandages or dressings characterised by the skin-adhering layer
    • A61F13/0253—Adhesive bandages or dressings characterised by the skin-adhering layer characterized by the adhesive material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F15/00—Auxiliary appliances for wound dressings; Dispensing containers for dressings or bandages
    • A61F15/004—Bandage protectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/002—Packages specially adapted therefor ; catheter kit packages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A61M35/006—Portable hand-held applicators having means for dispensing or spreading integral media using sponges, foams, absorbent pads or swabs as spreading means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M39/16—Tube connectors; Tube couplings having provision for disinfection or sterilisation
    • A61M39/162—Tube connectors; Tube couplings having provision for disinfection or sterilisation with antiseptic agent incorporated within the connector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/20—Closure caps or plugs for connectors or open ends of tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C1/00—Apparatus in which liquid or other fluent material is applied to the surface of the work by contact with a member carrying the liquid or other fluent material, e.g. a porous member loaded with a liquid to be applied as a coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D33/00—Details of, or accessories for, sacks or bags
    • B65D33/16—End- or aperture-closing arrangements or devices
    • B65D33/25—Riveting; Dovetailing; Screwing; using press buttons or slide fasteners
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D33/00—Details of, or accessories for, sacks or bags
    • B65D33/16—End- or aperture-closing arrangements or devices
    • B65D33/28—Strings or strip-like closures, i.e. draw closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/40—Packages formed by enclosing successive articles, or increments of material, in webs, e.g. folded or tubular webs, or by subdividing tubes filled with liquid, semi-liquid, or plastic materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B2050/314—Flexible bags or pouches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00051—Accessories for dressings
    • A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F15/00—Auxiliary appliances for wound dressings; Dispensing containers for dressings or bandages
    • A61F15/005—Bandage applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1586—Holding accessories for holding infusion needles on the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Closures For Containers (AREA)

Abstract

本公开内容描述了示例消毒涂药器，其可以与一种或多种清洁剂、抗菌剂和/或消毒剂组合使用，以减少或消除表面上的污染物。根据一些实施方案，本公开内容描述了所述涂药器可以包含不可渗透层和可渗透层，其中所述不可渗透层防止污染物从使用者的手转移至所述可渗透层和表面。

Description

消毒涂药器和包装技术
相关申请的交叉引用
本申请要求2013年2月1日提交的标题为“消毒涂药器和包装技术”的美国专利申请第13/757,318号的优先权，该申请要求2012年2月6日提交的标题为“消毒涂药器和保护装置”的美国临时专利申请第61/595,635号的优先权，这两者都在此通过引用而全部并入。
背景技术
医疗保健获得感染(HAI)已被公认为可预防性死亡率和发病率的一个重要原因。在美国，HAI每年失去近99,000条生命并且耗费几十亿美元在额外的治疗和住院治疗中。Klevens等人，2002年美国医院中医疗保健相关感染和死亡评估(Estimating Health Care-AssociatedInfection and Deaths in U.S.Hospitals,2002)，公共健康报告(PublicHealth Report)，2007年第122卷第160页。血管内导管、外科手术部位及侵入性程序部位的污染，往往会导致设备的拆卸和更换、长时间的肠外抗菌治疗以及延长的住院治疗和康复。
多重耐抗菌剂微生物的传播常常是由医疗保健提供者的手或医疗设备传播，从一个被宿主或受感染的患者传播至其他易感性患者。外科手术部位感染可能因皮肤的消毒准备措施不足导致。针对外科手术前部位的例行清洁和擦拭而广泛使用的葡萄糖酸氯己定(CHG)，已经导致在某些医院环境中耐甲氧西林(MRSA)和CHG两者的金黄色葡萄球菌的发病率增加。
附图说明
参照附图给出了详细的描述。在附图中，附图标记的最左边数字标识该附图标记首次出现在其中的附图。在不同的附图中采用相同的附图标记表示相似或相同的项目或特征。
图1示出一种示例消毒涂药器，其可包括不可渗透层和设置有清洁剂、抗菌剂或消毒剂的渗透层。
图2示出一种示例环境，此时使用者可能抓握所述示例消毒涂药器的不可渗透层。
图3A-图3C示出用于所述示例消毒涂药器的多种无菌包装技术。
图4是示出用于操作示例消毒涂药器的示例过程的流程图。
发明内容
概述
本公开内容描述了被设计成减少和/或预防感染的医疗涂药器。在一个实施方案中，本公开内容描述了示例涂药器或擦拭物(wipes)，其具有附着至可渗透吸收层和/或吸收底层的不可渗透层。所述涂药器或擦拭物的无菌包装被设计为当其被打开时使所述不可渗透层暴露于使用者，因此，防止该使用者手上存在的传染性病原体(infectious agents)转移至可渗透底层和患者或表面。在一些实施方案中，涂药器或擦拭物包含一种抗菌组合物，其可以单独使用或与一种或多种清洁剂、抗菌剂或消毒剂组合使用，以对血管内(IV)管道口、其他IV组件(例如，注射器、管腔、阀门等)、注射部位、抽血部位(例如，自静脉、动脉或毛细管)、医疗设备(例如，数字温度计或听诊器)、伤口部位、切口部位、腹膜透析部位、排泄部位或任何其他易受感染的部位或表面进行清洁、消毒和/或杀菌。
在一些实施方案中，本公开内容描述了不含不可渗透层、含有抗菌剂或消毒剂的示例涂药器，所述抗菌剂或消毒剂包括水、低分子量醇、过氧化物或过氧化物生成剂以及由可渗透材料所携带的螯合剂。在该实施方案中，所述可渗透材料可被用作涂药器或擦拭物以清洁、消毒和/或杀菌，这很像使用简单的酒精擦拭物。
下面的详细讨论始于标题为“示例抗菌组合物”的章节，该章节详细描述了可被包括在本文所述的医疗涂药器和装置中的示例抗菌组合物。接下来，本公开内容描述了“示例消毒涂药器”，然后是“消毒涂药器的示例包装”。下一步，本公开内容描述了用于操作示例消毒涂药器的“示例过程”。最后，本公开内容总结出简短的“结论”。
本概述(包括章节标题)被设置成介绍简化形式的概念的选择，所述概念进一步描述于下文中。本概述是为了读者的方便而设置，并不意在限制权利要求的范围，也不意在限制后续章节的范围。
示例抗菌组合物
在一个示例实施方案中，可与本文中所描述的方法结合使用的抗菌组合物可包括描述于，例如Tennican等人于2011年1月21日提交的国际专利申请第PCT/US2011/022150号以及Tennican于2012年11月28日提交的美国非临时专利申请第13/688,078中的那些，其通过引用并入本文。例如，所述抗菌组合物可包括水(H2O)、强性且无毒的螯合剂(如乙二胺四乙酸(EDTA)，例如EDTA二钠、EDTA二钠钙、EDTA镁、EDTA钾、EDTA镓)或柠檬酸钠(或EDTA或柠檬酸钠的酸、盐、衍生物或其他形式)、短链一元醇(例如，分子式为C2H5OH且经验式为C2H60的乙醇)，以及强性小分子氧化剂，如过氧化氢(H2O2)。在一个具体实例中，所述组合物可以基本上由水、EDTA、乙醇和过氧化氢组成。另外的成分可包括增稠剂、胶凝剂、表面活性剂、起泡剂和/或泡沫稳定剂。然而，在其他实例中，其他抗菌组合物可与本公开内容中所描述的涂药器和装置组合使用。
所述抗菌组合物可以是液体形式或凝胶形式，并且可以与一种或多种载体或稀释剂组合，这取决于特定应用的需要。例如，如果该抗菌组合物用作清洁剂，则该抗菌组合物可以是液体形式。在这种情况下，各组分的浓度可能取决于，例如消毒和/或灭菌的期望水平，无论是否将所述组合物直接应用至活体组织或应用至医疗装置，和/或为了避免刺激将被直接或间接地应用至的组织(例如，经由该组合物被应用至的医疗装置)。
除了在施加的时候提供灭菌之外，所述抗菌组合物也可以提供持久的防止污染的屏障。例如，即使在组合物的挥发性成分(例如，水、醇、过氧化氢等)已被蒸发后，所述螯合剂可以保留在处理过的表面上(例如，多用小瓶或端口清洁/保护装置、听诊器、手指、周围组织等)作为屏障从而提供抗菌、抗真菌或杀孢子(如，防止孢子萌发)、抗寄生虫、杀精子或使精子凝固(例如，降低精子的运动性)和抗病毒性质。通过剥夺细菌、孢子、寄生虫、真菌和病毒繁殖所需的组分环境(例如，铁、镁和锰)，所述螯合剂提供了防止污染的持久防御，即使在所述抗菌组合物的其他组分蒸发掉了之后。更进一步地，所述抗菌组合物中的过氧化氢可诱发所述抗菌组合物待被应用至的材料(例如，硅树脂材料)表面上的电荷(charge)，以使该材料更耐细菌或其他微生物。
当被应用至表面或材料时，以上所述的抗菌组合物还可以提供污染的可视指示，这样的指示可以允许使用者标记并清洁表面，以防止感染。
如在描述示例抗菌组合物的上下文中使用的术语“约”或“近似”应被解释为包括将是本领域中可接受的和/或已知的合理的误差区域。
示例涂药器
在本文中描述了多种医疗涂药器。参照图1和图2大致描述了示例医疗涂药器。
图1示出了示例消毒涂药器100的图示。该示例消毒涂药器包括被连接至可渗透吸收层104的不可渗透层102。该示例消毒涂药器100被示为具有正方形形状，但是替代的形状，例如圆形、矩形、椭圆形、多边形等皆被纳入考虑。在一些实施方案中，如图1中所示，不可渗透层102可以比可渗透层104略小。然而，在其他实施方案中，不可渗透层102可以比可渗透层104大或具有与可渗透层104基本相同的尺寸。用于不可渗透层102的组合物的示例材料包括但不限于聚乙烯、氧化硅涂覆的聚合物膜、聚丙烯、聚硅氧烷、聚四氟乙烯、聚氯乙烯、聚酯薄膜(mylar)或它们的混合物。
在一些实施方案中，不可渗透层102可具有有纹理的抓握表面106。不可渗透层102上的有纹理的抓握表面106可包括但不限于脊状的、粗糙的、凹凸不平的、线状的、点状的、网状的纹理等。不可渗透层102的有纹理的抓握表面106可允许使用者抓握并使用所述消毒涂药器，使得使用者的手滑落该涂药器并与待清洁、消毒或灭菌的表面接触的风险降至最小。
在另一个实施方案中，不可渗透层可具有围绕其周边或边缘设置的凸脊(未示出)。所述凸脊可另外存在于上述其他的有纹理的实施方案中或代替上述其他的有纹理的实施例存在。此外，所述脊可自不可渗透层的内表面升起，足以使得使用者的手滑落该涂药器并与待清洁、消毒或灭菌的表面接触的风险降至最小。
在又一实施方案中，不可渗透层102可以防止位于涂药器的使用者(例如使用者的手)上的污染物转移至可渗透层104以及潜在地转移至正被清洁、消毒或灭菌的表面。此外或可选地，不可渗透层102可以防止表面上的污染物转移至涂药器的使用者。
如图1和图2所示，示例消毒涂药器100包含可渗透吸收层和/或吸收层104，所述吸收层将允许消毒剂、抗菌剂或清洁剂渗透穿过所述层的全部或一部分。用于可渗透层104的示例材料包括但不限于淀粉聚合物、纤维素凝胶、聚乙烯泡沫、聚氨酯泡沫、硅氧烷开孔泡沫或它们的混合物。可渗透层104的某些实施方案可以包括，但不限于不同的表面处理(例如，狭槽、纵裂等)、表面抛光(surface finishes)(例如，宏观结构、微观结构或纳米结构等)、轮廓(例如，圆形、肋、凸起、指状物等)和/或它们的组合，以提供清洁和/或洗涤效率。
在部分实施方案中，可渗透层104中含有清洁剂，其包括但不限于，表面活性剂、洗涤剂或肥皂。在另一个实施方案中，可渗透层104含有低分子量的醇。在另一个实施方案中，可渗透层104含有过氧化物或过氧化物生成剂。在另一个实施方案中，可渗透层104包含螯合剂。在另一个实施方案中，可渗透层104包含前述部分中描述的示例抗菌组合物。所述示例消毒涂药器的可渗透层104用于与有机组织接触，所述有机组织包括但不限于人或动物组织。在另一实例中，可渗透层104用于与惰性材料接触，所述惰性材料包括但不限于医疗装置(例如温度计、听诊器、超声设备、耳镜、检眼镜、心电图单元、血压计、磅秤(scales)等)、多用途/剂量小瓶(vial)、血管内(IV)管道口或其他IV组件。
在又一实施方案中，示例消毒涂药器可在无不可渗透层102存在下构建。在该实施方案中，可渗透层104可包含前述部分中描述的示例抗菌组合物。
图2示出使用者的手试图抓住示例消毒涂药器100的不可渗透层102的图示200。该示例消毒涂药器100从侧面示出。在一些实施方案中，示例消毒涂药器100的使用者的抓握可通过不可渗透层102的有纹理的表面106变得容易。
一旦使用者抓住示例消毒涂药器100，该使用者可以使用涂药器100擦拭或刷洗被标记的表面，如人体组织或医疗装置。不可渗透层102提供防滑表面106以帮助涂药器的使用者的操作并提供防止污染物从使用者转移至表面或者防止污染物从表面转移至使用者的不可穿过的屏障。在一些实施方案中，使用者可以收到可视指示，该指示表示设置在可渗透层104内的抗菌组合物已经与一种或多种污染物接触，所述一种或多种污染物例如一种或多种细菌、一种或多种孢子、一种或多种寄生虫、一种或多种病毒、一种或多种体液或它们的混合物。所述可视指示可以是在被刷洗或擦拭的表面上的发泡或起泡的指示。
消毒涂药器的示例包装
上述各种涂药器中的任意一种都可被独立地无菌包装或无菌包装成在一系列包装中的多个涂药器的盒(kits)。此外，涂药器本身可以额外地或可替换地被容纳在包含UV防护材料的包装中以抑制清洁剂、抗菌剂或消毒剂的分解。
图3A显示了可以封装示例消毒涂药器100的无菌包装300的一个实施方案的图示。每个示例消毒涂药器可以通过将所述示例消毒涂药器夹在多层热塑性材料之间并通过例如声波焊接、微波焊接、热粘结等使各材料片围绕所述示例消毒涂药器的外周彼此密封而被独立地密封在袋或包中。在一些实施方案中，多个示例消毒涂药器可以如以上所述地密封在袋或包中。
在一些实施方案中，所述无菌包装可以包含穿孔线或刻痕线302和舌片(tab)304，以便于打开无菌包装300。使用者可以拉起无菌包装300上的舌片304，然后拉起穿孔线302以使示例消毒涂药器的不可渗透层暴露至使用者。
在一些实施方案中，无菌包装300包括但不限于箔袋、塑料衬袋、箔衬袋和/或塑料托盘。在一个实施方案中，通过将多个涂药器置于各热塑性材料片之间，然后采用上述密封方法中的任意一种使各层片材围绕每个防护盖(protective caps)的外周彼此密封，可以将多个涂药器包装在一连续的条带(strip)中。如图3B所示，多个涂药器可以连续地存储在通过穿孔306隔开的条带或套装(series)中。在一些实施方案中，所述连续条带中的每个包装可以包含具有相同清洁剂、抗菌剂或消毒剂的消毒涂药器。在其他实施方案中，所述连续条带中的每个包装可以包含具有不同浓度的相同清洁剂、抗菌剂或消毒剂的消毒涂药器。在其他实施方案中，所述连续条带中的每个包装可以包含具有与该条带中的相邻包装中存储的涂药器不同的清洁剂、抗菌剂或消毒剂的消毒涂药器。
图3C示出了另一示例无菌包装，以适应需要不同清洁剂、抗菌剂或消毒剂的特定多步骤医疗程序或适应在该医疗程序中的不同步骤中需要不同浓度的清洁剂、抗菌剂或消毒剂。例如，盒308可包括翼片(flap)或突起(projection)310，用于暴露含有清洁剂的第一涂药器312以清洁所希望的部位、暴露含有高浓度的消毒剂的第二涂药器314以对该部位进行消毒或灭菌、暴露含有低浓度的消毒剂的第三涂药器316以及含有甚至更低浓度的消毒剂的第四涂药器318以减少所述抗菌剂在所希望的部位处的残留浓度。盒308可包括但不限于塑料衬袋、箔衬袋和/或塑料托盘。应当理解的是，被包装在盒308内的涂药器，参照图3B如上所述，可以包含任意数量的涂药器，所述涂药器包含清洁剂、抗菌剂或消毒剂的任何数量的组合，或以适应不同医疗程序的步骤。在某些实施方案中，盒308还可以包括至少一个不含清洁剂、抗菌剂或消毒剂的涂药器。
示例过程
图4示出用于执行如上所述的操作示例消毒涂药器的技术的示例过程400。过程400以逻辑流程图示出。所描述的操作中的顺序不应被解释为限制，并且任何数量的所述操作可以以任意顺序和/或并行地组合以实现该过程。
在操作402中，可以标记待被清洁、消毒或灭菌的表面。例如，使用者可在开始医疗程序之前标记需要被消毒的表面，如人体皮肤。
在操作404中，无菌包装可被打开以暴露医疗涂药器的外表面。在图1和图3A的背景中，所述医疗涂药器可以在所述外表面上具有不可渗透层，并且所述无菌包装被配置成具有打开所述不可渗透层的舌片。
在操作406中，医疗涂药器可从无菌包装中移出。例如，可以通过抓住所述医疗涂药器的外表面上的不可渗透层而移出医疗涂药器。
在操作408中，可以将所述医疗涂药器应用至待被清洁、消毒或灭菌的被标记的表面。例如，所述医疗涂药器的含有清洁剂、抗菌剂或消毒剂的可渗透层可以在人体皮肤的一部分上进行擦拭、涂抹、轻敷或以其他方式移过。
最后，在操作410中，对应于将所述涂药器应用至表面，可以收到表示所述清洁剂、抗菌剂或消毒剂可能已与一种或多种细菌、一种或多种孢子、一种或多种寄生虫、一种或多种病毒、一种或多种体液或它们的混合物接触的可视指示。例如，诸如起泡或发泡的可视指示可存在于该表面上。
结论
虽然本公开内容描述了具有特定的结构特征和/或方法行为的实施方案，但应当理解，权利要求并不一定受限于这些具体特征或所描述的行为。相反，这些具体特征和行为仅是落入本发明的权利要求范围内的说明性的一些实施例。

Claims (20)

1.一种医疗涂药器，其包括：
不可渗透层，所述不可渗透层具有被构造成与使用者交界的外表面；
可渗透吸收层，所述可渗透吸收层具有被连接至所述不可渗透层的顶面和与一表面交界的底面；和
设置在所述可渗透吸收层内并由其携带的清洁剂、抗菌剂或消毒剂。
2.如权利要求1所述的医疗涂药器，其中所述不可渗透层包括聚乙烯、氧化硅涂覆的聚合物膜、聚丙烯、聚硅氧烷、聚四氟乙烯、聚氯乙烯、聚酯薄膜或它们的混合物。
3.如权利要求2所述的医疗涂药器，其中所述不可渗透层的外表面具有脊状纹理、线状纹理、点状纹理、网状纹理或它们的组合。
4.如权利要求1所述的医疗涂药器，其中所述可渗透吸收层包括淀粉聚合物、纤维素凝胶、聚乙烯泡沫、聚氨酯泡沫、硅氧烷开孔泡沫，或者它们的混合物。
5.如权利要求1所述的医疗涂药器，其中所述可渗透吸收层的底面具有被构造成刷洗材料的崎岖纹理、粗糙纹理、光滑纹理、微观纹理、纳米纹理或它们的组合。
6.如权利要求1所述的医疗涂药器，其中所述清洁剂、抗菌剂或消毒剂包括表面活性剂、水、低分子量醇、过氧化物或过氧化物生成剂或螯合剂。
7.如权利要求1所述的医疗涂药器，其中所述抗菌剂或消毒剂包括：
约5-约50mg/ml的乙二胺四乙酸(EDTA)；
按体积计至多约70％的乙醇；
按体积计至多约7.5％的过氧化氢；和
水。
8.根据权利要求1所述的医疗涂药器，其进一步包括存储所述医疗涂药器的无菌包装，所述包装被构造成当打开时露出所述不可渗透层的外表面。
9.如权利要求8所述的医疗涂药器，其中所述无菌包装被构造成将多个医疗涂药器独立并连续地存储于条带中，其中每个医疗涂药器独立地被包含在条带中并且可含有与所述条带中的相邻医疗涂药器相同或不同的清洁剂、抗菌剂或消毒剂。
10.如权利要求8所述的医疗涂药器，其中所述无菌包装被构造成将多个医疗涂药器独立并连续地存储于套装中，其中所述套装的每个医疗涂药器不包含抗菌剂或消毒剂、或适应医疗程序中的特定步骤的特定的清洁剂、抗菌剂或消毒剂，并且所述包装还被构造成基于所述医疗程序中的步骤来打开。
11.一种预防传染性病原体传播的方法，其包括：
标记待被清洁、消毒或灭菌的表面；和
将医疗涂药器应用至所述表面，所述医疗涂药器包括：
不可渗透背衬，所述不可渗透背衬具有与使用者交界的外表面；
可渗透面，所述可渗透面具有被连接至所述不可渗透背衬的第一层和被构造成与所述表面交界的第二层；和
设置在所述可渗透面内的清洁剂、抗菌剂或消毒剂，所述清洁剂、抗菌剂或消毒剂包括表面活性剂、水、低分子量醇、过氧化物或过氧化物生成剂或螯合剂的一种或多种。
12.如权利要求11所述的方法，其中待被清洁、消毒或灭菌的表面是有机组织区域或惰性材料区域。
13.如权利要求11所述的方法，其中将医疗涂药器应用至所述表面进一步包括：
打开被构造成露出所述医疗涂药器的不可渗透背衬的外表面的无菌包装；
通过抓住所述医疗涂药器的不可渗透背衬的外表面而移出所述医疗涂药器；
用含有所述清洁剂、抗菌剂或消毒剂的可渗透面的第二层擦拭被标记的表面；以及
接收至少部分地反映擦拭的可视指示，该指示表示所述清洁剂、抗菌剂或消毒剂已与一种或多种细菌、一种或多种孢子、一种或多种寄生虫、一种或多种病毒、一种或多种体液或它们的混合物接触。
14.如权利要求13所述的方法，其中所述无菌包装被构造成独立地存储多个医疗涂药器，其中每个医疗涂药器被连续地存储在条带中，并且所述条带中的每个医疗涂药器含有不同浓度的清洁剂、抗菌剂或消毒剂。
15.如权利要求13所述的方法，其中所述不可渗透背衬的外表面被构造为具有脊状、线状、点状、粘性或网状纹理。
16.一种医疗涂药器，其包括：
可渗透吸收材料，所述可渗透吸收材料具有被构造成与表面交界的外部基底；
设置在所述可渗透吸收材料内的抗菌剂或消毒剂，所述抗菌剂或消毒剂包含水、过氧化氢、过氧化脲、乙二胺四乙酸(EDTA)、EDTA的盐、柠檬酸钠或其他生物相容的螯合剂或醇中的至少一种或多种；和
存储所述可渗透吸收材料的无菌包装。
17.如权利要求16所述的医疗涂药器，其中所述可渗透吸收材料包括淀粉聚合物、纤维素凝胶、聚乙烯泡沫、和/或硅氧烷开孔泡沫。
18.如权利要求16所述的医疗涂药器，其中所述抗菌剂或消毒剂包括：
约5-约50mg/ml的乙二胺四乙酸(EDTA)；
按体积计至多约70％的乙醇；
按体积计至多约7.5％的过氧化氢；和
水。
19.如权利要求16所述的医疗涂药器，其中所述无菌包装允许多个医疗涂药器独立并连续地存储。
20.如权利要求16所述的医疗涂药器，其进一步包括：
被连接至所述可渗透吸收材料的外顶部的柔性不可渗透材料，当所述无菌包装被打开时所述柔性不可渗透材料被显示给使用者。
CN201380007893.6A 2012-02-06 2013-02-04 消毒涂药器和包装技术 Pending CN104203290A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261595635P 2012-02-06 2012-02-06
US61/595,635 2012-02-06
US13/757,318 2013-02-01
US13/757,318 US9039967B2 (en) 2012-02-06 2013-02-01 Antiseptic applicators and packaging techniques
PCT/US2013/024635 WO2013119504A1 (en) 2012-02-06 2013-02-04 Antiseptic applicators and packaging techniques

Publications (1)

Publication Number Publication Date
CN104203290A true CN104203290A (zh) 2014-12-10

Family

ID=48901941

Family Applications (4)

Application Number Title Priority Date Filing Date
CN201380008084.7A Active CN104185486B (zh) 2012-02-06 2013-02-04 组合式盖涂抹器
CN201380006373.3A Pending CN104168894A (zh) 2012-02-06 2013-02-04 具有抗菌组合物的胶粘贴片
CN201380007894.0A Expired - Fee Related CN104244992B (zh) 2012-02-06 2013-02-04 便携式医疗设备保护器
CN201380007893.6A Pending CN104203290A (zh) 2012-02-06 2013-02-04 消毒涂药器和包装技术

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CN201380008084.7A Active CN104185486B (zh) 2012-02-06 2013-02-04 组合式盖涂抹器
CN201380006373.3A Pending CN104168894A (zh) 2012-02-06 2013-02-04 具有抗菌组合物的胶粘贴片
CN201380007894.0A Expired - Fee Related CN104244992B (zh) 2012-02-06 2013-02-04 便携式医疗设备保护器

Country Status (14)

Country Link
US (5) US20130199946A1 (zh)
EP (4) EP2811988B1 (zh)
JP (5) JP6522947B2 (zh)
KR (4) KR20140130427A (zh)
CN (4) CN104185486B (zh)
AU (4) AU2013217607B2 (zh)
BR (4) BR112014019290B1 (zh)
CA (4) CA2863702C (zh)
HK (4) HK1203422A1 (zh)
IN (2) IN2014DN06505A (zh)
MX (4) MX366560B (zh)
SG (5) SG11201404502WA (zh)
TR (1) TR201815518T4 (zh)
WO (4) WO2013119509A1 (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106674573A (zh) * 2016-12-26 2017-05-17 海宁市佳峰彩印包装有限公司 一种彩印包装复合膜加工方法
CN107380497A (zh) * 2017-07-20 2017-11-24 广州易航电子有限公司 一种涂液包及其制备方法
CN110860040A (zh) * 2019-11-18 2020-03-06 东莞市人民医院 导电膏涂抹装置及导电膏涂抹方法

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8740864B2 (en) 2005-11-17 2014-06-03 Becton, Dickinson And Company Patient fluid line access valve antimicrobial cap/cleaner
US20130199946A1 (en) 2012-02-06 2013-08-08 Hyprotek, Inc. Portable Medical Device Protectors
EP2814538B1 (en) * 2012-02-15 2018-04-18 Np Medical Inc. Multi-purpose protective covering for use on a medical device
US20140319000A1 (en) * 2013-04-26 2014-10-30 Kenneth Irwin Fishberger Disposable stethoscope covers and methods of use
WO2015103727A1 (zh) * 2014-01-07 2015-07-16 富利乐科技（深圳）有限公司 医用设备清洁消毒装置及清洁消毒器
US20160000508A1 (en) * 2014-07-03 2016-01-07 Darren Finn BARRIER KiT FOR EMT MONITORING EQUIPMENT
US10925281B2 (en) 2014-11-26 2021-02-23 Microban Products Company Surface disinfectant with residual biocidal property
US10834922B2 (en) 2014-11-26 2020-11-17 Microban Products Company Surface disinfectant with residual biocidal property
US10842147B2 (en) 2014-11-26 2020-11-24 Microban Products Company Surface disinfectant with residual biocidal property
US11033023B2 (en) 2014-11-26 2021-06-15 Microban Products Company Surface disinfectant with residual biocidal property
US9527660B2 (en) 2014-12-31 2016-12-27 Hyprotek, Inc. Individually sealed antiseptic applicators
US10485892B2 (en) 2015-03-10 2019-11-26 Covalon Technologies Inc. Method for local reduction of microbial skin flora
US10357579B2 (en) 2015-10-05 2019-07-23 Texas Medical Group SOPARFI S.a.r.l. Device port cleaner
CA2999329A1 (en) * 2015-10-16 2017-04-20 Opko Diagnostics, Llc Articles and methods for preparing a surface for obtaining a patient sample
US10576261B2 (en) 2015-12-11 2020-03-03 Turnstone Technologies, LLC Device male port cleaner
CA3010519C (en) 2016-01-18 2024-01-23 Becton, Dickinson And Company Disinfection cap for iv needleless connectors
US11503824B2 (en) 2016-05-23 2022-11-22 Microban Products Company Touch screen cleaning and protectant composition
US10660683B2 (en) * 2016-05-27 2020-05-26 In2Bones Usa, Llc Method for sterile packaging of K-wire and cap
US10918456B2 (en) * 2017-02-03 2021-02-16 Sony Olympus Medical Solutions Inc. Protective cover and medical observation apparatus
US10099048B2 (en) * 2017-03-10 2018-10-16 Turnstone Technologies, LLC Device port cleaner
EP3375472B1 (en) 2017-03-15 2021-01-27 Asset Medikal Tasarim Sanayi ve Ticaret A.S. Pen-like portable device for cleaning needle-free iv-connectors
CA3059090A1 (en) 2017-04-19 2018-10-25 Benjamin S. Paras Disposable antiseptic wipe apparatus
TR201706687A2 (tr) * 2017-05-05 2018-11-21 T C Istanbul Medipol Ueniversitesi Bi̇r gi̇yi̇m eşyasi
US10821481B1 (en) 2017-09-05 2020-11-03 Zoran Lesic Disinfecting wipe
CN111278476B (zh) 2017-09-22 2023-01-17 贝克顿·迪金森公司 用作导管封管液的4％柠檬酸三钠溶液
US20190133573A1 (en) * 2017-11-03 2019-05-09 Dura Tap Llc Suturing kit
AU2018364931B2 (en) * 2017-11-11 2022-10-06 James Bowen Stiehl Irrigation device and system for delivering pressurized fluid to same for wound lavage and biofilm control
CN108553753A (zh) * 2018-01-04 2018-09-21 浙江大学 深静脉留置导管防感染保护帽
US10899510B2 (en) 2018-10-17 2021-01-26 Nicole Thomas Vial assembly with cap with disinfectant and related methods
CN109512524B (zh) * 2018-12-27 2021-06-04 南通市第一老年病医院 腔镜手术放置袋
KR20220044243A (ko) 2019-06-11 2022-04-07 가부시끼가이샤 제이엠에스 의료용 기기
IT202000012190A1 (it) * 2020-05-25 2021-11-25 Deep S R L Contenitore igienico monouso
US20210393890A1 (en) * 2020-06-17 2021-12-23 William Lynders Pain Reducing Anesthetic Cooling Device
KR102265386B1 (ko) * 2020-07-21 2021-06-14 박상균 소독제를 내포한 살균 필름
CN112402099A (zh) * 2020-11-11 2021-02-26 问兰药业(苏州)有限公司 一种轻便高效的烧烫伤敷料
WO2022132639A1 (en) * 2020-12-14 2022-06-23 Icahn School Of Medicine At Mount Sinai Hemostasis valve device
IT202200007733A1 (it) * 2022-04-20 2023-10-20 Vito Francesco Giustiniani Contenitore monouso con funzione interna disinfettante
CN115350320B (zh) * 2022-09-05 2023-09-26 海南一鸿实业发展有限公司 一种外用抗菌泡沫敷料及其制备工艺
CN117735050B (zh) * 2024-02-21 2024-04-30 山东显微智能科技有限公司 一种一次性内窥镜转运装置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696393A (en) * 1981-10-19 1987-09-29 Laipply Thomas C Applicator wipe for inviscid fluids
CN2511272Y (zh) * 2001-10-09 2002-09-18 韩平 伤口促愈贴
CN101279102A (zh) * 2006-09-12 2008-10-08 泰科保健集团有限合伙公司 薄膜敷料
WO2011028965A2 (en) * 2009-09-02 2011-03-10 Hyprotek, Inc. Antimicrobial medical dressings and protecting wounds and catheter sites
CN102133421A (zh) * 2011-03-17 2011-07-27 山东赛克赛斯药业科技有限公司 一种快速止血创伤敷料及其制备方法与应用

Family Cites Families (155)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB350384A (en) 1929-03-04 1931-06-04 John Barnard Kirsch Dressing for wounds ready for use
US4188234A (en) * 1965-08-24 1980-02-12 Plains Chemical Development Co. Chelation
US3607760A (en) 1969-06-09 1971-09-21 Edna M Mcintyre Cleaning composition for pet stains
US3851649A (en) 1973-03-21 1974-12-03 Kendall & Co Catheterization package
US3860348A (en) 1973-06-06 1975-01-14 Schick Inc Applicator package for fluid products
JPS532302U (zh) * 1976-06-24 1978-01-11
SE7607337L (sv) 1976-06-28 1977-12-29 Atlas Copco Ab Sett och anordning for brytning av ett fast material
US4291697A (en) 1980-04-18 1981-09-29 Stephen Georgevich Cleaning and application device for medical purposes
US4412254A (en) 1981-06-24 1983-10-25 Rca Corporation Television receiver high voltage protection circuit
JPS583476U (ja) * 1981-06-27 1983-01-10 末峰　明 ミニパック製治療用品
US5046608A (en) * 1981-10-19 1991-09-10 Laipply Thomas C Combined fluid storage container and applicator device and method
US4446967A (en) 1982-05-07 1984-05-08 Halkyard Douglas R Germicide sleeve for dental and medical instruments
US4440207A (en) * 1982-05-14 1984-04-03 Baxter Travenol Laboratories, Inc. Antibacterial protective cap for connectors
JPS59500801A (ja) 1982-05-14 1984-05-10 バクスタ−、インターナショナル　インコ−ポレイテッド コネクタ−のための抗バクテリア性保護キャップ
US4588400A (en) 1982-12-16 1986-05-13 Johnson & Johnson Products, Inc. Liquid loaded pad for medical applications
EP0169839B1 (en) 1984-01-23 1991-09-25 LAIPPLY, Thomas C. Alcohol wipe and methods
US4564010A (en) 1984-04-18 1986-01-14 Daubert Coated Products Inc. Pressure sensitive adhesive film for medical use
FR2587207B1 (fr) 1985-09-19 1987-12-24 Merck Sharp & Dohme Ensemble pour le conditionnement et l'administration d'une solution ophtalmique
JPS6274364A (ja) 1985-09-27 1987-04-06 株式会社　ニツシヨ− 医療用具
GB8622698D0 (en) 1986-09-20 1986-10-29 Smith & Nephew Ass Dispenser
US4830856A (en) * 1987-01-27 1989-05-16 Peppers James M Chelation product
US5009652A (en) 1987-10-16 1991-04-23 Morgan Cheryle I Medical sponges and wipes with a barrier impermeable to infectious agents
US4811847A (en) * 1988-03-14 1989-03-14 Reif Thomas H Urinary catheter package
US4954239A (en) 1988-04-15 1990-09-04 Mueller Louis H Prefilled catheter tip syringe kit
US5438984A (en) 1988-09-08 1995-08-08 Sudor Partners Apparatus and method for the collection of analytes on a dermal patch
US5171523A (en) 1988-10-03 1992-12-15 Williams Robert M Method and apparatus for disinfecting objects
US5041264A (en) * 1988-10-03 1991-08-20 Williams Robert M Method and apparatus for disinfecting objects
US4893956A (en) 1988-11-18 1990-01-16 Blistex Inc. Packaging for medicaments
JP2563538B2 (ja) 1988-11-30 1996-12-11 松下電器産業株式会社 電気湯沸し器
JPH0610978Y2 (ja) * 1989-05-18 1994-03-23 ニチバン株式会社 消毒用綿球
US5015228A (en) 1989-06-05 1991-05-14 Eastman Kodak Company Sterilizing dressing device and method for skin puncture
EP0544778A1 (en) 1990-09-17 1993-06-09 Medipro Sciences Limited Bilayer wound dressing
JP2978601B2 (ja) 1991-07-30 1999-11-15 山中産業株式会社 抽出バッグ用タッグ糸および抽出用バッグ
AU3057792A (en) 1991-11-06 1993-06-07 Bioderm, Inc. Occlusive wound dressing and applicator
JPH0544111U (ja) * 1991-11-26 1993-06-15 株式会社塚田メデイカル・リサーチ 医療用消毒セツト
JPH0743749U (ja) * 1991-11-29 1995-09-12 イミュ株式会社 化粧料，外用剤等の塗布，除去用の衛生用具
US5222600A (en) 1992-07-28 1993-06-29 Stoddard James T Autoclave pouch
US6063029A (en) * 1992-12-07 2000-05-16 Hisamitsu Pharmaceutical Co., Inc. Diagnostic patch and method for diagnosis using the same
JPH08191855A (ja) 1992-12-09 1996-07-30 Imamura Hideki 注射用消毒綿
WO1994024972A1 (en) 1993-05-04 1994-11-10 Lisa Fernandez Geng Wound dressing
US5454798A (en) * 1993-05-14 1995-10-03 Mentor Corporation Disposable urine bag
WO1995001736A1 (en) 1993-07-06 1995-01-19 Utecht Leo J Personal protection apparatus
JPH0743749A (ja) 1993-07-30 1995-02-14 Sharp Corp ２端子非線形素子及びその製造方法
DE4332093C2 (de) 1993-09-22 1995-07-13 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Acetylsalicylsäure und Verfahren zu seiner Herstellung
US5731275A (en) 1994-04-05 1998-03-24 Universite De Montreal Synergistic detergent and disinfectant combinations for decontaminating biofilm-coated surfaces
GB9411429D0 (en) 1994-06-08 1994-07-27 Seton Healthcare Group Plc Wound dressings
US5556375A (en) 1994-06-16 1996-09-17 Hercules Incorporated Wound dressing having a fenestrated base layer
US5569207A (en) * 1994-10-13 1996-10-29 Quinton Instrument Company Hydrocolloid dressing
US5554135A (en) 1995-02-17 1996-09-10 Menyhay; Steve Z. Sterile medical injection port and cover method and apparatus
WO1996032142A1 (en) 1995-04-12 1996-10-17 Hopp Robert B Skin patch for use in contact immunotherapy
JP3605437B2 (ja) 1995-05-19 2004-12-22 大日本印刷株式会社 貼着体
MX9601936A (es) 1995-07-07 1997-01-31 Becton Dickinson Co Una bandeja mejorada para la preparacion de la piel para uso en procedimientos quirurgicos.
US5772031A (en) 1996-02-15 1998-06-30 Zimmer, Inc. Package for an elongated medical product
US5976117A (en) 1996-09-25 1999-11-02 3M Innovative Properties Company Wound dressing
JPH10110268A (ja) 1996-10-03 1998-04-28 Nissin Electric Co Ltd 医療用被覆材
US5975082A (en) 1997-03-10 1999-11-02 Kimberly-Clark Worldwide, Inc. Tear-away surgical drape
US6071541A (en) 1998-07-31 2000-06-06 Murad; Howard Pharmaceutical compositions and methods for managing skin conditions
US20030007939A1 (en) 1998-07-31 2003-01-09 Howard Murad Pharmaceutical compositions and methods for managing dermatological conditions
US6168800B1 (en) 1998-08-20 2001-01-02 Medwrap Corporation Antimcrobial multi-layer island dressing
WO2000027438A1 (en) 1998-11-06 2000-05-18 Universite De Montreal Improved bactericidal and non-bactericidal solutions for removing biofilms
US6274232B1 (en) 1999-06-18 2001-08-14 The Procter & Gamble Company Absorbent sheet material having cut-resistant layer and method for making the same
FR2804601B1 (fr) 2000-02-04 2002-04-26 3X Engineering Dispositif d'application de principes actifs utilisables dans le domaine pharmaceutique ou cosmetique
US6455066B1 (en) 2000-03-10 2002-09-24 Epicept Corporation Intradermal-penetration agents for topical local anesthetic administration
JP5038576B2 (ja) 2000-06-13 2012-10-03 久光製薬株式会社 貼付剤
CN1511014A (zh) 2001-04-13 2004-07-07 用于医疗的无菌箱
US7482021B1 (en) 2001-05-11 2009-01-27 Tison Kelley H Two-sided wipe for cleaning and drying a skin surface
US8541472B2 (en) 2001-12-05 2013-09-24 Aseptica, Inc. Antiseptic compositions, methods and systems
GB2382775B (en) 2001-12-06 2005-05-25 Johnson & Johnson Medical Ltd Controlled release therapeutic wound dressings
JP4132911B2 (ja) 2002-03-25 2008-08-13 日東電工株式会社 貼付製剤
CN2546003Y (zh) 2002-04-29 2003-04-23 康乐保(中国)有限公司 一种方便护理插引流管伤口的自粘敷料
US6769546B2 (en) 2002-07-03 2004-08-03 L. John Busch Epidural anesthesia kit
JP2004049540A (ja) 2002-07-19 2004-02-19 Chisso Corp 抗菌性粘着フィルム及びそれを用いた救急絆創膏
EP1393710A1 (en) 2002-08-21 2004-03-03 The Procter & Gamble Company A method of applying an oral composition
US9597067B2 (en) 2002-10-04 2017-03-21 Ethicon, Inc. Packaged antimicrobial medical device and method of preparing same
US8112973B2 (en) 2002-10-04 2012-02-14 Ethicon, Inc. Method of making a packaged antimicrobial suture
US8100872B2 (en) 2002-10-23 2012-01-24 Tyco Healthcare Group Lp Medical dressing containing antimicrobial agent
US20040129581A1 (en) 2002-11-22 2004-07-08 Janet Tompkins Barium swallowing kit
AU2003294367B2 (en) 2002-12-31 2009-11-12 Bsn Medical Gmbh Wound dressing
US7762044B2 (en) * 2003-01-27 2010-07-27 Medtronic Vascular, Inc. Packaging for stent delivery systems
US20060142684A1 (en) 2003-04-11 2006-06-29 Shanbrom Technologies, Llc Oxygen releasing material
JP2004351632A (ja) 2003-05-27 2004-12-16 Meisei Sansho Kk 薬液含浸シート
SI1644024T1 (sl) 2003-06-06 2019-11-29 Univ Texas Protimikrobne raztopine za izpiranje
US7179813B2 (en) 2003-06-11 2007-02-20 Wyeth Bicyclic indolyl derivatives and methods for their use as serotonergic agents
US7282186B2 (en) 2003-06-20 2007-10-16 Lake Jr Robert F Decontamination device
US20040261196A1 (en) 2003-06-27 2004-12-30 The Procter & Gamble Company Fabric care compositions for lipophilic fluid systems incorporating an antimicrobial agent
DE10331192A1 (de) * 2003-07-10 2005-02-03 Paul Hartmann Ag Hautfreundliches Einwegprodukt
US20050034731A1 (en) 2003-08-13 2005-02-17 Rousseau Robert A. Surgical wound closure device
AU2004271775A1 (en) 2003-09-13 2005-03-24 Reckitt & Colman Overseas Limited Skincare compositions comprising salicyclic acid
US7118545B2 (en) * 2003-10-14 2006-10-10 Boyde Sandra M Wound dressing retainer and fastening device
JP4476593B2 (ja) 2003-10-16 2010-06-09 日東電工株式会社 医療用粘着性抗菌シート
BRPI0416387A (pt) 2003-11-11 2007-02-21 Veckis Ind Ltd composição desinfetante e métodos de confecção e uso da mesma
GB2408207A (en) 2003-11-24 2005-05-25 Johnson & Johnson Medical Ltd Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme
US20050129897A1 (en) 2003-12-11 2005-06-16 Kimberly-Clark Worldwide, Inc. Disposable scrubbing product
MXPA06007343A (es) 2003-12-23 2007-01-26 Hemcon Inc Equipos, sistemas y metodos para curacion tisular formados a partir de estructuras de esponja polimerica hidrofilica tales como por ejemplo quitosana.
US7204368B2 (en) 2003-12-29 2007-04-17 Cheaure Sarah F Resealable package
JP2005350571A (ja) * 2004-06-10 2005-12-22 Sekisui Chem Co Ltd 熱可塑性樹脂発泡体シート及び熱可塑性樹脂発泡体シートの製造方法
CN2705167Y (zh) 2004-02-20 2005-06-22 佟刚 胶原贴敷料
WO2005089341A2 (en) 2004-03-16 2005-09-29 Bull Brian S Method and device for coronary artery bypass
US20050249791A1 (en) 2004-05-07 2005-11-10 3M Innovative Properties Company Antimicrobial articles
CA2564763C (en) 2004-05-14 2012-08-07 Virox Technologies Inc. Hydrogen peroxide-based skin disinfectant
FR2870828B1 (fr) * 2004-05-26 2006-08-18 Oreal Dispositif de conditionnement et d'application d'un produit
US7478962B2 (en) 2004-05-26 2009-01-20 L'oreal Device for packaging and application of a product
TWI257564B (en) 2004-06-11 2006-07-01 Youeal Electronics Co Ltd Metallic keypad and method for making the same
US20050281890A1 (en) 2004-06-18 2005-12-22 San Chandan K Methods and compositions for wound healing
CN1711845A (zh) 2004-06-25 2005-12-28 殷生章 一种可杀灭非典肺炎冠状病毒的消毒剂
US8017826B2 (en) * 2004-09-16 2011-09-13 Dsu Medical Corporation Injection and hemostasis site
AU2005286771B2 (en) * 2004-09-17 2011-04-21 David M. Dixon Wound care dressing and method using same
US7506760B2 (en) 2005-01-10 2009-03-24 Grossman Victor A Packaging and dispensers for adhesive backed elements
EP1887863A2 (en) * 2005-02-07 2008-02-20 SiShield Technologies Methods and compositions for biocidal treatments
WO2006089139A2 (en) 2005-02-15 2006-08-24 Lab39, Llc Oral care cleaning compositions and methods
JP4756497B2 (ja) 2005-02-25 2011-08-24 株式会社吉野工業所 容器用パッキン
US7749453B2 (en) 2005-05-04 2010-07-06 Bionostics, Inc. Devices, systems, and methods for the containment and use of liquid solutions
US20070014685A1 (en) 2005-07-15 2007-01-18 Halt Gerald B Sr Personal sanitation device
US7320404B2 (en) 2005-08-10 2008-01-22 Zimmer Technology, Inc. Medical packaging
JP2007044258A (ja) 2005-08-10 2007-02-22 Transcutaneous Technologies Inc 注射針挿入孔付き経皮吸収用パッチ
WO2007044624A2 (en) 2005-10-06 2007-04-19 Stickley Robert F Wearable stethoscope sanitizing device
GB0525504D0 (en) 2005-12-14 2006-01-25 Bristol Myers Squibb Co Antimicrobial composition
WO2007075928A2 (en) 2005-12-22 2007-07-05 Provex Technologies, Llc. Integrated patch and assay device with visual detection means
AU2007238826B2 (en) 2006-04-11 2012-09-13 Kpr U.S., Llc Wound dressings with anti-microbial and zinc-containing agents
US8162899B2 (en) 2006-05-18 2012-04-24 Hyprotek, Inc. Intravascular line and port cleaning methods, methods of administering an agent intravascularly, methods of obtaining/testing blood, and devices for performing such methods
EP2023996B1 (en) 2006-06-08 2011-02-02 Hollister Incorporated Catheter product package and method of forming same
US20090324508A1 (en) 2006-07-06 2009-12-31 Centennial Ventures B.V. Broad Spectrum and Skin Friendly Disinfecting Composition
GB0614278D0 (en) 2006-07-19 2006-08-30 Insense Ltd Hydrogen peroxide delivery system
US7780794B2 (en) * 2006-07-21 2010-08-24 Ivera Medical Corporation Medical implement cleaning device
US8403898B2 (en) 2006-11-21 2013-03-26 Mark R. Moore Apparatus and method for deploying a surgical preparation
US8647326B2 (en) 2007-01-16 2014-02-11 Catheter Connections, Inc. System for cleaning luer connectors
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
US8336152B2 (en) 2007-04-02 2012-12-25 C. R. Bard, Inc. Insert for a microbial scrubbing device
US8065773B2 (en) 2007-04-02 2011-11-29 Bard Access Systems, Inc. Microbial scrub brush
US20100240799A1 (en) 2007-06-13 2010-09-23 3M Innovative Properties Company Antimicrobial film-forming composition, antimicrobial film, and method of verifying the presence of an antimicrobial film
US20090010998A1 (en) 2007-07-03 2009-01-08 Marchitto Kevin S Drug-delivery patch comprising a dissolvable layer and uses thereof
US20090028750A1 (en) * 2007-07-23 2009-01-29 Ryan Dana Wm Cleaning and Disinfection Swabbing Device for Needle-Free Intravenous (IV) Connectors
US20090036541A1 (en) 2007-08-02 2009-02-05 Donald David Mardis Applicator and chemical combination for better topical anesthesia
BRPI0819417A2 (pt) 2007-12-17 2015-03-17 Novapharm Res Australia "composição que não mancha que é bactericida, fungicida e viricida"
US8388894B2 (en) * 2008-03-20 2013-03-05 Psi Medical Catheter Care, Llc Apparatus and method for sterilizing a tubular medical line port
WO2009136957A1 (en) 2008-05-06 2009-11-12 Ferlic Michael J Universal sterilizing tool
US8777504B2 (en) * 2008-07-03 2014-07-15 Retractable Technologies, Inc. Cleaning tool
US20100030170A1 (en) 2008-08-01 2010-02-04 Keith Alan Keller Absorptive Pad
WO2010128554A1 (ja) 2009-05-08 2010-11-11 日昭クインズ株式会社 医療具用容器及び医療キット
WO2010131253A2 (en) 2009-05-13 2010-11-18 Hadasit Medical Research Services And Development Ltd. Stethoscope disinfection device
US8486004B1 (en) * 2009-07-02 2013-07-16 Centurion Medical Products Corporation Dressing having integral antimicrobial
CN201481841U (zh) 2009-08-07 2010-05-26 刘书光 一种重症监护室专用消毒箱
WO2011019132A1 (ko) 2009-08-14 2011-02-17 중앙대학교 산학협력단 도전성 접착제, 이를 이용한 반도체의 실장방법 및 웨이퍼 레벨 패키지
CN201481842U (zh) * 2009-08-14 2010-05-26 中国人民解放军第二炮兵装备研究院第二研究所 一种便携式洗消器
US20110184382A1 (en) 2009-08-20 2011-07-28 Cady Timothy B Multi-purpose articles for sanitizing and capping luer access valves
JP2011056183A (ja) 2009-09-14 2011-03-24 Olympus Corp 医療用シート状部材
JP5370844B2 (ja) 2009-09-30 2013-12-18 レンゴー株式会社 アリルイソチオシアネート揮散製剤
CN103108643B (zh) 2010-01-22 2016-10-26 希普罗特克有限公司 包含过氧化物、醇和螯合剂的抗菌剂
US8496625B2 (en) 2010-05-26 2013-07-30 Nxstage Medical, Inc. Safe needle methods, apparatus, and systems
WO2011163124A1 (en) 2010-06-23 2011-12-29 Medical Components, Inc. Cleaner for medical device
ES2530417T3 (es) 2010-07-14 2015-03-02 Bard Access Systems Inc Dispositivo de apósito para su uso con una cánula o un catéter
CN103957955A (zh) * 2011-11-28 2014-07-30 希普罗特克有限公司 包含残留屏障膜的抗菌成分
US20130199946A1 (en) 2012-02-06 2013-08-08 Hyprotek, Inc. Portable Medical Device Protectors
US9522001B2 (en) 2012-04-12 2016-12-20 Operating Room Innovations, Inc. Surgical appliance kit and system for releasably securing a surgical appliance to a surgical field and method of assembling the surgical applicance kit
CA2881361C (en) 2012-08-08 2022-03-08 Board Of Regents, The University Of Texas System Antimicrobial compositions comprising glyceryl nitrates

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696393A (en) * 1981-10-19 1987-09-29 Laipply Thomas C Applicator wipe for inviscid fluids
CN2511272Y (zh) * 2001-10-09 2002-09-18 韩平 伤口促愈贴
CN101279102A (zh) * 2006-09-12 2008-10-08 泰科保健集团有限合伙公司 薄膜敷料
WO2011028965A2 (en) * 2009-09-02 2011-03-10 Hyprotek, Inc. Antimicrobial medical dressings and protecting wounds and catheter sites
WO2011028965A3 (en) * 2009-09-02 2011-07-21 Hyprotek, Inc. Antimicrobial medical dressings and protecting wounds and catheter sites
CN102133421A (zh) * 2011-03-17 2011-07-27 山东赛克赛斯药业科技有限公司 一种快速止血创伤敷料及其制备方法与应用

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106674573A (zh) * 2016-12-26 2017-05-17 海宁市佳峰彩印包装有限公司 一种彩印包装复合膜加工方法
CN107380497A (zh) * 2017-07-20 2017-11-24 广州易航电子有限公司 一种涂液包及其制备方法
CN110860040A (zh) * 2019-11-18 2020-03-06 东莞市人民医院 导电膏涂抹装置及导电膏涂抹方法

Also Published As

Publication number Publication date
WO2013119508A1 (en) 2013-08-15
CA2863855C (en) 2019-12-31
AU2013217602A1 (en) 2014-08-21
CA2863702A1 (en) 2013-08-15
HK1203408A1 (zh) 2015-10-30
KR20140125775A (ko) 2014-10-29
JP2018008096A (ja) 2018-01-18
KR20140120899A (ko) 2014-10-14
EP2812033B1 (en) 2018-08-08
AU2013217603B2 (en) 2016-03-31
BR112014018688B1 (pt) 2019-06-25
CA2863844C (en) 2020-07-14
JP2015507954A (ja) 2015-03-16
JP6671098B2 (ja) 2020-03-25
SG10201605854PA (en) 2016-09-29
US20130202483A1 (en) 2013-08-08
MX349941B (es) 2017-08-21
JP2015508675A (ja) 2015-03-23
JP2015509386A (ja) 2015-03-30
BR112014019290A8 (pt) 2017-07-11
BR112014018667B1 (pt) 2019-06-25
US20130199947A1 (en) 2013-08-08
CN104185486B (zh) 2017-09-15
IN2014DN06503A (zh) 2015-06-12
US10080620B2 (en) 2018-09-25
EP2812033A1 (en) 2014-12-17
US10617472B2 (en) 2020-04-14
MX362284B (es) 2019-01-10
JP6823572B2 (ja) 2021-02-03
BR112014019290B1 (pt) 2021-06-15
CA2863855A1 (en) 2013-08-15
BR112014018667A2 (zh) 2017-06-20
KR20140130427A (ko) 2014-11-10
CN104185486A (zh) 2014-12-03
BR112014018688A8 (pt) 2017-07-11
JP6522947B2 (ja) 2019-05-29
AU2013217603A1 (en) 2014-08-21
CA2863841A1 (en) 2013-08-15
BR112014018688A2 (zh) 2017-06-20
CN104168894A (zh) 2014-11-26
SG11201404504RA (en) 2014-10-30
EP2812048B1 (en) 2018-03-14
AU2013217606B2 (en) 2017-03-02
US9039967B2 (en) 2015-05-26
TR201815518T4 (tr) 2018-11-21
CN104244992B (zh) 2018-03-06
WO2013119505A1 (en) 2013-08-15
AU2013217606A1 (en) 2014-08-21
CA2863702C (en) 2020-06-23
JP6416629B2 (ja) 2018-10-31
US20130204212A1 (en) 2013-08-08
AU2013217602B2 (en) 2016-11-10
MX366560B (es) 2019-07-12
EP2812048A4 (en) 2015-10-21
EP2811988A1 (en) 2014-12-17
KR20140130470A (ko) 2014-11-10
BR112014019233A2 (pt) 2017-06-20
EP2812032A4 (en) 2015-10-14
JP6272783B2 (ja) 2018-01-31
MX2014009432A (es) 2014-11-10
SG11201404359RA (en) 2014-11-27
EP2812033A4 (en) 2015-10-14
US20130199946A1 (en) 2013-08-08
BR112014018667A8 (pt) 2017-07-11
EP2812032B1 (en) 2017-03-29
MX2014009435A (es) 2014-11-10
BR112014019233B1 (pt) 2021-08-24
CA2863841C (en) 2021-02-16
US9192443B2 (en) 2015-11-24
HK1204582A1 (zh) 2015-11-27
CN104244992A (zh) 2014-12-24
MX2014009433A (es) 2014-11-10
EP2812032A1 (en) 2014-12-17
MX366557B (es) 2019-07-12
EP2812048A1 (en) 2014-12-17
HK1203858A1 (zh) 2015-11-06
AU2013217607B2 (en) 2017-05-25
AU2013217607A1 (en) 2014-08-28
HK1203422A1 (zh) 2015-10-30
WO2013119509A1 (en) 2013-08-15
JP2015509485A (ja) 2015-03-30
EP2811988A4 (en) 2015-10-21
WO2013119504A1 (en) 2013-08-15
SG11201404502WA (en) 2014-10-30
MX2014009434A (es) 2014-11-10
IN2014DN06505A (zh) 2015-06-12
SG11201404503TA (en) 2014-10-30
BR112014019290A2 (zh) 2017-06-20
EP2811988B1 (en) 2018-04-04
BR112014019233A8 (pt) 2017-07-11
US20170209229A1 (en) 2017-07-27
CA2863844A1 (en) 2013-08-15

Similar Documents

Publication Publication Date Title
CN104203290A (zh) 消毒涂药器和包装技术
CN107812286B (zh) 端口和表面清洁设备和技术

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1203422

Country of ref document: HK

CB02 Change of applicant information

Inventor after: Tennican Patrick O.

Inventor after: Phipps L. Myles

Inventor before: Tennican Patrick O.

CB03 Change of inventor or designer information
RJ01 Rejection of invention patent application after publication

Application publication date: 20141210

RJ01 Rejection of invention patent application after publication
REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1203422

Country of ref document: HK