CL2024000667A1 - Compuestos clorados de tetralina y composiciones farmacéuticas - Google Patents
Compuestos clorados de tetralina y composiciones farmacéuticasInfo
- Publication number
- CL2024000667A1 CL2024000667A1 CL2024000667A CL2024000667A CL2024000667A1 CL 2024000667 A1 CL2024000667 A1 CL 2024000667A1 CL 2024000667 A CL2024000667 A CL 2024000667A CL 2024000667 A CL2024000667 A CL 2024000667A CL 2024000667 A1 CL2024000667 A1 CL 2024000667A1
- Authority
- CL
- Chile
- Prior art keywords
- chlorinated
- pharmaceutical compositions
- tetralin compounds
- tetralin
- compounds
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- CXWXQJXEFPUFDZ-UHFFFAOYSA-N tetralin Chemical class C1=CC=C2CCCCC2=C1 CXWXQJXEFPUFDZ-UHFFFAOYSA-N 0.000 title abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present disclosures are directed to chlorinated tetralin compounds and pharmaceutical compositions.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163241844P | 2021-09-08 | 2021-09-08 | |
| US202163263635P | 2021-11-05 | 2021-11-05 | |
| US202263365125P | 2022-05-20 | 2022-05-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2024000667A1 true CL2024000667A1 (es) | 2024-09-13 |
Family
ID=83598639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2024000667A CL2024000667A1 (es) | 2021-09-08 | 2024-03-06 | Compuestos clorados de tetralina y composiciones farmacéuticas |
Country Status (13)
| Country | Link |
|---|---|
| US (8) | US11504354B1 (es) |
| EP (1) | EP4399203A1 (es) |
| JP (1) | JP2024531670A (es) |
| KR (1) | KR20240056531A (es) |
| AU (1) | AU2022342176A1 (es) |
| CA (1) | CA3230422A1 (es) |
| CL (1) | CL2024000667A1 (es) |
| CO (1) | CO2024002891A2 (es) |
| IL (1) | IL311284A (es) |
| MX (1) | MX2024002872A (es) |
| PE (1) | PE20241629A1 (es) |
| TW (1) | TW202328075A (es) |
| WO (1) | WO2023039475A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10118242B2 (en) | 2010-06-17 | 2018-11-06 | Illinois Tool Works Inc. | Welding power supply with power take-off shaft |
| TW202328068A (zh) | 2021-09-01 | 2023-07-16 | 美商斯普林渥克斯治療有限公司 | 尼羅司他（ｎｉｒｏｇａｃｅｓｔａｔ）之合成 |
| US11504354B1 (en) * | 2021-09-08 | 2022-11-22 | SpringWorks Therapeutics Inc.. | Chlorinated tetralin compounds and pharmaceutical compositions |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO5160260A1 (es) | 1999-02-19 | 2002-05-30 | Lilly Co Eli | Secretagogos de la hormona del crecimiento derivados de imi- dazol 1,4- substituido |
| GT200100147A (es) | 2000-07-31 | 2002-06-25 | Derivados de imidazol | |
| WO2005092864A1 (en) | 2004-03-23 | 2005-10-06 | Pfizer Products Inc. | Imidazole compounds for the treatment of neurodegenerative disorders |
| US20190185559A1 (en) | 2016-09-02 | 2019-06-20 | The Brigham And Women's Hospital, Inc. | Compositions and methods for treating neoplasias |
| WO2019053727A1 (en) | 2017-09-18 | 2019-03-21 | Ramot At Tel-Aviv University Ltd. | REDIFFERENCING IN VITRO DEVELOPED CELLS FROM HUMAN PANCREATIC ISLAND BEA CELLS ADULPTED BY SMALL MOLECULE INHIBITORS OF THE SIGNALING PATH |
| US10590087B1 (en) | 2019-08-09 | 2020-03-17 | Pfizer Inc. | Solid state forms of (S)-2-(((S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-N-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-yl)pentanamide and uses thereof |
| EP4010322A1 (en) * | 2019-08-09 | 2022-06-15 | Pfizer Inc. | Solid state forms of (s)-2-(((s)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-n-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1h-imidazol-4-yl)pentanamide and uses thereof |
| US11504354B1 (en) * | 2021-09-08 | 2022-11-22 | SpringWorks Therapeutics Inc.. | Chlorinated tetralin compounds and pharmaceutical compositions |
-
2022
- 2022-07-08 US US17/860,682 patent/US11504354B1/en active Active
- 2022-09-08 JP JP2024515641A patent/JP2024531670A/ja active Pending
- 2022-09-08 US US17/995,031 patent/US20240217937A1/en active Pending
- 2022-09-08 WO PCT/US2022/076116 patent/WO2023039475A1/en active Application Filing
- 2022-09-08 CA CA3230422A patent/CA3230422A1/en active Pending
- 2022-09-08 IL IL311284A patent/IL311284A/en unknown
- 2022-09-08 EP EP22786237.2A patent/EP4399203A1/en active Pending
- 2022-09-08 MX MX2024002872A patent/MX2024002872A/es unknown
- 2022-09-08 KR KR1020247009567A patent/KR20240056531A/ko unknown
- 2022-09-08 TW TW111134199A patent/TW202328075A/zh unknown
- 2022-09-08 PE PE2024000392A patent/PE20241629A1/es unknown
- 2022-09-08 AU AU2022342176A patent/AU2022342176A1/en active Pending
- 2022-10-04 US US17/937,990 patent/US11612588B1/en active Active
- 2022-10-04 US US17/937,994 patent/US20230088856A1/en not_active Abandoned
- 2022-10-19 US US18/047,932 patent/US20230091097A1/en not_active Abandoned
-
2023
- 2023-04-17 US US18/301,742 patent/US11844780B2/en active Active
- 2023-04-17 US US18/301,754 patent/US11807611B2/en active Active
- 2023-10-20 US US18/490,993 patent/US20240058307A1/en active Pending
-
2024
- 2024-03-06 CL CL2024000667A patent/CL2024000667A1/es unknown
- 2024-03-08 CO CONC2024/0002891A patent/CO2024002891A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4399203A1 (en) | 2024-07-17 |
| US20240058307A1 (en) | 2024-02-22 |
| US20230090557A1 (en) | 2023-03-23 |
| US20230091097A1 (en) | 2023-03-23 |
| AU2022342176A1 (en) | 2024-03-28 |
| PE20241629A1 (es) | 2024-08-09 |
| US11504354B1 (en) | 2022-11-22 |
| TW202328075A (zh) | 2023-07-16 |
| CA3230422A1 (en) | 2023-03-16 |
| US11844780B2 (en) | 2023-12-19 |
| KR20240056531A (ko) | 2024-04-30 |
| JP2024531670A (ja) | 2024-08-29 |
| US20230310379A1 (en) | 2023-10-05 |
| US20240217937A1 (en) | 2024-07-04 |
| US11807611B2 (en) | 2023-11-07 |
| IL311284A (en) | 2024-05-01 |
| CO2024002891A2 (es) | 2024-06-27 |
| WO2023039475A1 (en) | 2023-03-16 |
| US11612588B1 (en) | 2023-03-28 |
| US20230088856A1 (en) | 2023-03-23 |
| MX2024002872A (es) | 2024-03-22 |
| US20230250065A1 (en) | 2023-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CL2024000667A1 (es) | Compuestos clorados de tetralina y composiciones farmacéuticas | |
| ECSP19003773A (es) | Compuestos heterocíclicos como inmunomoduladores | |
| EA201990615A1 (ru) | Пирролобензодиазепиновые конъюгаты | |
| CL2015000942A1 (es) | Compuestos de benceno sustituido. | |
| BR112018012756A2 (pt) | compostos heterocíclicos como imunomoduladores | |
| CL2016002516A1 (es) | “compuestos derivados de espirociclo sustituidos, inhibidores atx; composición farmacéutica que los comprende; y su uso en el tratamiento del cáncer, inflamaciones, dolor neuropático, enfermedades fibróticas, trombosis, entre otros”. pct | |
| MX2019001096A (es) | Antagonistas del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos. | |
| CY1124811T1 (el) | Προφαρμακα φαινολικων αγωνιστων trpv1 | |
| BR112018010271A2 (pt) | material cristalino sintético emm-28, sua preparação e uso | |
| TR201901445T4 (tr) | Il2rbeta/yaygın gamma zinciri antikorları. | |
| CL2016002835A1 (es) | “compuestos derivados de pladienolida con un resto piridinico; composición farmacéutica que los comprende; y su uso en el tratamiento del cáncer”. pct | |
| EP4248968A3 (en) | Tlr7/8 antagonists and uses thereof | |
| EA201890858A1 (ru) | 2,4-дигидроксиникотинамиды как агонисты apj | |
| MX2019015744A (es) | Composiciones farmaceuticas. | |
| EA201991073A1 (ru) | Ингибиторы magl | |
| EA201991074A1 (ru) | Ингибиторы magl | |
| EA200970916A1 (ru) | Соединения 5,6-дигидро-1н-пиридин-2-она | |
| CL2017002856A1 (es) | Compuestos de tioéter como inhibidores de la nitrificación | |
| EA201891586A1 (ru) | Антипролиферативные соединения и их фармацевтические композиции и применения | |
| CL2015002897A1 (es) | Inhibidores de bace1 | |
| EA201892822A1 (ru) | Новые антибактериальные соединения | |
| CL2011000979A1 (es) | Compuestos derivados ftalazina 1,4-disustituida; composicion farmaceutica; y su uso en el tratamiento del cancer. | |
| EA201892500A1 (ru) | Применение фракции лигнина в качестве антифитопатогенного агента и содержащие ее антифитопатогенные композиции | |
| EA201992328A1 (ru) | Фармацевтическая композиция, содержащая ленватиниба мезилат | |
| EA201990158A1 (ru) | Производные бензодиоксана и их фармацевтическое применение |