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CL2016000882A1 - Composiciones de arni contra el componente c5 del complemento y métodos para su uso (divisional de sol. n°2710-15). - Google Patents

Composiciones de arni contra el componente c5 del complemento y métodos para su uso (divisional de sol. n°2710-15).

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Publication number
CL2016000882A1
CL2016000882A1 CL2016000882A CL2016000882A CL2016000882A1 CL 2016000882 A1 CL2016000882 A1 CL 2016000882A1 CL 2016000882 A CL2016000882 A CL 2016000882A CL 2016000882 A CL2016000882 A CL 2016000882A CL 2016000882 A1 CL2016000882 A1 CL 2016000882A1
Authority
CL
Chile
Prior art keywords
complement
methods
arni
compositions
against component
Prior art date
Application number
CL2016000882A
Other languages
English (en)
Inventor
Muthiah Manoharan
Martin Maier
Satyanarayana Kuchimanchi
Klaus Charisse
Brian Bettencourt
Kevin Fitzgerald
Donald Foster
Anna Borodovsky
James Butler
Kallanthottathil Rajeev
Original Assignee
Alnylam Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alnylam Pharmaceuticals Inc filed Critical Alnylam Pharmaceuticals Inc
Publication of CL2016000882A1 publication Critical patent/CL2016000882A1/es

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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Abstract

ÁCIDO RIBONUCLEICO DE HEBRA DOBLE (ARNhd) PARA INHBIR LA EXPRESIÓN DEL COMPONENTE C5 DEL COMPLEMENTO; CÉLULA; VECTOR; COMPOSICIÓN FARMACÉUTICA Y MÉTODOS PARA SU USO (DIVISIONAL DE SOL. N°2710-15).
CL2016000882A 2013-03-14 2016-04-14 Composiciones de arni contra el componente c5 del complemento y métodos para su uso (divisional de sol. n°2710-15). CL2016000882A1 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361782531P 2013-03-14 2013-03-14
US201361837399P 2013-06-20 2013-06-20
US201361904579P 2013-11-15 2013-11-15
US201361912777P 2013-12-06 2013-12-06
US201461942367P 2014-02-20 2014-02-20

Publications (1)

Publication Number Publication Date
CL2016000882A1 true CL2016000882A1 (es) 2016-12-09

Family

ID=50678278

Family Applications (4)

Application Number Title Priority Date Filing Date
CL2015002710A CL2015002710A1 (es) 2013-03-14 2015-09-14 Composiciones de arni contra el componente c5 del complemento y métodos para su uso.
CL2016000882A CL2016000882A1 (es) 2013-03-14 2016-04-14 Composiciones de arni contra el componente c5 del complemento y métodos para su uso (divisional de sol. n°2710-15).
CL2017002014A CL2017002014A1 (es) 2013-03-14 2017-08-07 Composiciones de arni contra el componente c5 del complemento y métodos para su uso. (divisional solicitud 2710-2015)
CL2019000107A CL2019000107A1 (es) 2013-03-14 2019-01-14 Composiciones de arni contra el componente c5 del complemento y métodos para su uso.(divisional solicitud 201702014)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2015002710A CL2015002710A1 (es) 2013-03-14 2015-09-14 Composiciones de arni contra el componente c5 del complemento y métodos para su uso.

Family Applications After (2)

Application Number Title Priority Date Filing Date
CL2017002014A CL2017002014A1 (es) 2013-03-14 2017-08-07 Composiciones de arni contra el componente c5 del complemento y métodos para su uso. (divisional solicitud 2710-2015)
CL2019000107A CL2019000107A1 (es) 2013-03-14 2019-01-14 Composiciones de arni contra el componente c5 del complemento y métodos para su uso.(divisional solicitud 201702014)

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EP (2) EP2970974B1 (es)
JP (4) JP6524060B2 (es)
KR (4) KR102605775B1 (es)
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AU (3) AU2014244116B9 (es)
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CA (2) CA3216595A1 (es)
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CR (1) CR20150493A (es)
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DK (1) DK2970974T3 (es)
DO (1) DOP2015000234A (es)
EA (1) EA201591707A1 (es)
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