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CL2008001577A1 - Metodo para tratar una leucemia positiva en un sujeto resistente a imatinib que comprende el uso de un compuesto derivado de 3-ciano-quinolina. - Google Patents

Metodo para tratar una leucemia positiva en un sujeto resistente a imatinib que comprende el uso de un compuesto derivado de 3-ciano-quinolina.

Info

Publication number
CL2008001577A1
CL2008001577A1 CL200801577A CL2008001577A CL2008001577A1 CL 2008001577 A1 CL2008001577 A1 CL 2008001577A1 CL 200801577 A CL200801577 A CL 200801577A CL 2008001577 A CL2008001577 A CL 2008001577A CL 2008001577 A1 CL2008001577 A1 CL 2008001577A1
Authority
CL
Chile
Prior art keywords
quinolina
ciano
imatinib
understands
treat
Prior art date
Application number
CL200801577A
Other languages
English (en)
Inventor
Becker Hewes
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2008001577(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CL2008001577A1 publication Critical patent/CL2008001577A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CL200801577A 2007-06-01 2008-05-30 Metodo para tratar una leucemia positiva en un sujeto resistente a imatinib que comprende el uso de un compuesto derivado de 3-ciano-quinolina. CL2008001577A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93265007P 2007-06-01 2007-06-01

Publications (1)

Publication Number Publication Date
CL2008001577A1 true CL2008001577A1 (es) 2008-07-25

Family

ID=39639071

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200801577A CL2008001577A1 (es) 2007-06-01 2008-05-30 Metodo para tratar una leucemia positiva en un sujeto resistente a imatinib que comprende el uso de un compuesto derivado de 3-ciano-quinolina.

Country Status (24)

Country Link
US (1) US11103497B2 (es)
EP (4) EP3002009B1 (es)
JP (3) JP5888853B2 (es)
KR (1) KR101493543B1 (es)
CN (1) CN101686973B (es)
AU (1) AU2008260070B9 (es)
BR (1) BRPI0812355A2 (es)
CA (3) CA2964162C (es)
CL (1) CL2008001577A1 (es)
CY (2) CY1115251T1 (es)
DK (2) DK3002009T3 (es)
ES (2) ES2881391T3 (es)
HK (1) HK1142812A1 (es)
HU (1) HUE055524T2 (es)
IL (1) IL202407A0 (es)
MX (1) MX2009013069A (es)
PA (1) PA8782301A1 (es)
PL (2) PL2478905T3 (es)
PT (2) PT3002009T (es)
RU (1) RU2464026C2 (es)
SI (2) SI2478905T1 (es)
TW (1) TW200908982A (es)
WO (1) WO2008150957A2 (es)
ZA (1) ZA200908480B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3002009B1 (en) 2007-06-01 2021-07-07 Wyeth LLC Treatment of imatinib resistant chronic myelogenous leukemia having the mutaton 1457t>c in the bcrabl gene using the compound bosutinib
WO2012122011A2 (en) 2011-03-04 2012-09-13 Glaxosmithkline Llc Amino-quinolines as kinase inhibitors
TWI547494B (zh) 2011-08-18 2016-09-01 葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之胺基喹唑啉類
TWI592417B (zh) 2012-09-13 2017-07-21 葛蘭素史克智慧財產發展有限公司 胺基喹唑啉激酶抑制劑之前藥
AR092530A1 (es) 2012-09-13 2015-04-22 Glaxosmithkline Llc Compuesto de amino-quinolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
EP2958911B1 (en) 2013-02-21 2017-10-18 GlaxoSmithKline Intellectual Property Development Limited Quinazolines as kinase inhibitors
KR101733665B1 (ko) * 2015-05-06 2017-05-10 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 진세노사이드 F1 또는 Rg3을 유효성분으로 포함하는 글리벡 내성 백혈병 예방 또는 치료용 약학 조성물
AU2020332367A1 (en) * 2019-08-22 2022-02-17 Biohaven Therapeutics Ltd. Molecules that bind to TDP-43 for the treatment of amyotrophic lateral sclerosis and related disorders
CN115944636A (zh) * 2022-11-01 2023-04-11 华南师范大学 博舒替尼在抑制i-motif结构上的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002008A (en) 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6297258B1 (en) 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
CA2434526C (en) * 2001-01-25 2011-11-01 Bristol Myers Squibb Company Methods of administering epothilone analogs for the treatment of cancer
EP2341133A1 (en) 2001-10-05 2011-07-06 Novartis AG Mutated Abl kinase domains
TWI275390B (en) * 2002-04-30 2007-03-11 Wyeth Corp Process for the preparation of 7-substituted-3- quinolinecarbonitriles
US20050010780A1 (en) * 2003-07-09 2005-01-13 Kane John Richard Method and apparatus for providing access to personal information
US7417148B2 (en) * 2003-11-06 2008-08-26 Wyeth 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML)
KR20080011403A (ko) 2005-04-25 2008-02-04 화이자 인크. 미오스타틴에 대한 항체
PL1896470T3 (pl) * 2005-05-16 2011-03-31 Irm Llc Pochodne pirolopirydynowe jako inhibitory kinazy białkowej
EP1904654A2 (en) 2005-07-15 2008-04-02 Brystol-Myers Squibb Company Methods of identifying and treating individuals exhibiting mutant src kinase polypeptides
ES2533464T3 (es) 2005-10-06 2015-04-10 Eli Lilly And Company Anticuerpos anti-miostatina
EP1948820A2 (en) 2005-11-04 2008-07-30 Bristol-Myers Squibb Pharma Company T315a and f317i mutations of bcr-abl kinase domain
EP3002009B1 (en) * 2007-06-01 2021-07-07 Wyeth LLC Treatment of imatinib resistant chronic myelogenous leukemia having the mutaton 1457t>c in the bcrabl gene using the compound bosutinib

Also Published As

Publication number Publication date
SI3002009T1 (sl) 2021-09-30
CA2688467A1 (en) 2008-12-11
AU2008260070A1 (en) 2008-12-11
DK2478905T3 (da) 2014-06-30
RU2009144128A (ru) 2011-07-20
PL2478905T3 (pl) 2014-10-31
EP2478905A2 (en) 2012-07-25
PA8782301A1 (es) 2009-01-23
EP2152267A2 (en) 2010-02-17
CN101686973A (zh) 2010-03-31
EP3002009B1 (en) 2021-07-07
CN101686973B (zh) 2013-06-19
RU2464026C2 (ru) 2012-10-20
WO2008150957A2 (en) 2008-12-11
US20080318971A1 (en) 2008-12-25
MX2009013069A (es) 2010-03-17
KR101493543B1 (ko) 2015-02-13
EP2478905B1 (en) 2014-05-14
IL202407A0 (en) 2010-06-30
JP2016074700A (ja) 2016-05-12
CA2964162A1 (en) 2008-12-11
HK1142812A1 (en) 2010-12-17
ZA200908480B (en) 2010-08-25
HUE055524T2 (hu) 2021-11-29
EP2777704A2 (en) 2014-09-17
WO2008150957A3 (en) 2009-08-06
CY1115251T1 (el) 2017-01-04
PT3002009T (pt) 2021-08-02
AU2008260070B9 (en) 2012-01-19
ES2477567T3 (es) 2014-07-17
DK3002009T3 (da) 2021-08-02
ES2881391T3 (es) 2021-11-29
CY1124391T1 (el) 2022-07-22
AU2008260070B2 (en) 2011-08-18
EP3002009A2 (en) 2016-04-06
BRPI0812355A2 (pt) 2015-01-27
SI2478905T1 (sl) 2014-07-31
KR20100017983A (ko) 2010-02-16
JP2010529038A (ja) 2010-08-26
TW200908982A (en) 2009-03-01
PT2478905E (pt) 2014-07-16
CA2868899A1 (en) 2008-12-11
JP2014111629A (ja) 2014-06-19
PL3002009T3 (pl) 2021-12-13
CA2688467C (en) 2015-05-12
CA2868899C (en) 2017-06-13
EP2777704A3 (en) 2015-01-21
EP2478905A3 (en) 2013-01-16
JP5888853B2 (ja) 2016-03-22
CA2964162C (en) 2019-12-31
US11103497B2 (en) 2021-08-31
EP3002009A3 (en) 2016-07-06

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